Peter Kent Jackson - Publications

Affiliations: 
Cell Regulation Genentech, Inc. 
 Stanford University, Palo Alto, CA 
Website:
https://med.stanford.edu/profiles/peter-jackson

122 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Lin CH, Wang Z, Duque-Afonso J, Wong SH, Demeter J, Loktev AV, Somervaille TCP, Jackson PK, Cleary ML. Oligomeric self-association contributes to E2A-PBX1-mediated oncogenesis. Scientific Reports. 9: 4915. PMID 30894657 DOI: 10.1038/s41598-019-41393-w  0.48
2016 Ding S, Mooney N, Li B, Kelly MR, Feng N, Loktev AV, Sen A, Patton JT, Jackson PK, Greenberg HB. Comparative Proteomics Reveals Strain-Specific β-TrCP Degradation via Rotavirus NSP1 Hijacking a Host Cullin-3-Rbx1 Complex. Plos Pathogens. 12: e1005929. PMID 27706223 DOI: 10.1371/journal.ppat.1005929  0.48
2016 Boudreau A, Purkey HE, Hitz A, Robarge K, Peterson D, Labadie S, Kwong M, Hong R, Gao M, Del Nagro C, Pusapati R, Ma S, Salphati L, Pang J, Zhou A, ... ... Jackson PK, et al. Metabolic plasticity underpins innate and acquired resistance to LDHA inhibition. Nature Chemical Biology. PMID 27479743 DOI: 10.1038/nchembio.2143  1
2016 Toriyama M, Lee C, Taylor SP, Duran I, Cohn DH, Bruel AL, Tabler JM, Drew K, Kelly MR, Kim S, Park TJ, Braun DA, Pierquin G, Biver A, Wagner K, ... ... Jackson PK, et al. Corrigendum: The ciliopathy-associated CPLANE proteins direct basal body recruitment of intraflagellar transport machinery. Nature Genetics. 48: 970. PMID 27463398 DOI: 10.1038/ng0816-970b  0.56
2016 Toriyama M, Lee C, Taylor SP, Duran I, Cohn DH, Bruel AL, Tabler JM, Drew K, Kelly MR, Kim S, Park TJ, Braun D, Pierquin G, Biver A, Wagner K, ... ... Jackson PK, et al. The ciliopathy-associated CPLANE proteins direct basal body recruitment of intraflagellar transport machinery. Nature Genetics. PMID 27158779 DOI: 10.1038/ng.3558  0.56
2016 Hilgendorf KI, Johnson CT, Jackson PK. The primary cilium as a cellular receiver: organizing ciliary GPCR signaling. Current Opinion in Cell Biology. 39: 84-92. PMID 26926036 DOI: 10.1016/j.ceb.2016.02.008  1
2015 Gholkar AA, Senese S, Lo YC, Capri J, Deardorff WJ, Dharmarajan H, Contreras E, Hodara E, Whitelegge JP, Jackson PK, Torres JZ. Tctex1d2 associates with short-rib polydactyly syndrome proteins and is required for ciliogenesis. Cell Cycle (Georgetown, Tex.). 14: 1116-25. PMID 25830415 DOI: 10.4161/15384101.2014.985066  0.64
2014 Giles RH, Ajzenberg H, Jackson PK. 3D spheroid model of mIMCD3 cells for studying ciliopathies and renal epithelial disorders. Nature Protocols. 9: 2725-31. PMID 25356583 DOI: 10.1038/nprot.2014.181  1
2014 Jackson PK. Regulating microtubules and genome stability via the CUL7/3M syndrome complex and CUL9. Molecular Cell. 54: 713-5. PMID 24905004 DOI: 10.1016/j.molcel.2014.05.024  1
2014 Del Nagro CJ, Choi J, Xiao Y, Rangell L, Mohan S, Pandita A, Zha J, Jackson PK, O'Brien T. Chk1 inhibition in p53-deficient cell lines drives rapid chromosome fragmentation followed by caspase-independent cell death. Cell Cycle (Georgetown, Tex.). 13: 303-14. PMID 24247149 DOI: 10.4161/cc.27055  1
2014 Thomas S, Wright KJ, Le Corre S, Micalizzi A, Romani M, Abhyankar A, Saada J, Perrault I, Amiel J, Litzler J, Filhol E, Elkhartoufi N, Kwong M, Casanova JL, Boddaert N, ... ... Jackson PK, et al. A homozygous PDE6D mutation in Joubert syndrome impairs targeting of farnesylated INPP5E protein to the primary cilium. Human Mutation. 35: 137-46. PMID 24166846 DOI: 10.1002/humu.22470  1
2013 O'Brien T, Oeh J, Xiao Y, Liang X, Vanderbilt A, Qin A, Yang L, Lee LB, Ly J, Cosino E, LaCap JA, Ogasawara A, Williams S, Nannini M, Liederer BM, ... Jackson P, et al. Supplementation of nicotinic acid with NAMPT inhibitors results in loss of in vivo efficacy in NAPRT1-deficient tumor models. Neoplasia (New York, N.Y.). 15: 1314-29. PMID 24403854 DOI: 10.1593/neo.131718  1
2013 Loktev AV, Jackson PK. Neuropeptide Y family receptors traffic via the Bardet-Biedl syndrome pathway to signal in neuronal primary cilia. Cell Reports. 5: 1316-29. PMID 24316073 DOI: 10.1016/j.celrep.2013.11.011  0.48
2013 Xiao Y, Elkins K, Durieux JK, Lee L, Oeh J, Yang LX, Liang X, DelNagro C, Tremayne J, Kwong M, Liederer BM, Jackson PK, Belmont LD, Sampath D, O'Brien T. Dependence of tumor cell lines and patient-derived tumors on the NAD salvage pathway renders them sensitive to NAMPT inhibition with GNE-618. Neoplasia (New York, N.Y.). 15: 1151-60. PMID 24204194 DOI: 10.1593/neo.131304  1
2013 Xiao Y, Ramiscal J, Kowanetz K, Del Nagro C, Malek S, Evangelista M, Blackwood E, Jackson PK, O'Brien T. Identification of preferred chemotherapeutics for combining with a CHK1 inhibitor. Molecular Cancer Therapeutics. 12: 2285-95. PMID 24038068 DOI: 10.1158/1535-7163.MCT-13-0404  1
2013 Magnaghi P, D'Alessio R, Valsasina B, Avanzi N, Rizzi S, Asa D, Gasparri F, Cozzi L, Cucchi U, Orrenius C, Polucci P, Ballinari D, Perrera C, Leone A, Cervi G, ... ... Jackson PK, et al. Covalent and allosteric inhibitors of the ATPase VCP/p97 induce cancer cell death. Nature Chemical Biology. 9: 548-56. PMID 23892893 DOI: 10.1038/nchembio.1313  1
2013 Blackwood E, Epler J, Yen I, Flagella M, O'Brien T, Evangelista M, Schmidt S, Xiao Y, Choi J, Kowanetz K, Ramiscal J, Wong K, Jakubiak D, Yee S, Cain G, ... ... Jackson PK, et al. Combination drug scheduling defines a "window of opportunity" for chemopotentiation of gemcitabine by an orally bioavailable, selective ChK1 inhibitor, GNE-900. Molecular Cancer Therapeutics. 12: 1968-80. PMID 23873850 DOI: 10.1158/1535-7163.MCT-12-1218  1
2013 Mukhopadhyay S, Jackson PK. Cilia, tubby mice, and obesity. Cilia. 2: 1. PMID 23351214 DOI: 10.1186/2046-2530-2-1  1
2013 Mukhopadhyay S, Wen X, Ratti N, Loktev A, Rangell L, Scales SJ, Jackson PK. The ciliary G-protein-coupled receptor Gpr161 negatively regulates the Sonic hedgehog pathway via cAMP signaling. Cell. 152: 210-23. PMID 23332756 DOI: 10.1016/j.cell.2012.12.026  1
2013 Lahtela J, Corson LB, Hemmes A, Brauer MJ, Koopal S, Lee J, Hunsaker TL, Jackson PK, Verschuren EW. A high-content cellular senescence screen identifies candidate tumor suppressors, including EPHA3. Cell Cycle (Georgetown, Tex.). 12: 625-34. PMID 23324396 DOI: 10.4161/cc.23515  1
2013 Polucci P, Magnaghi P, Angiolini M, Asa D, Avanzi N, Badari A, Bertrand J, Casale E, Cauteruccio S, Cirla A, Cozzi L, Galvani A, Jackson PK, Liu Y, Magnuson S, et al. Alkylsulfanyl-1,2,4-triazoles, a new class of allosteric valosine containing protein inhibitors. Synthesis and structure-activity relationships. Journal of Medicinal Chemistry. 56: 437-50. PMID 23245311 DOI: 10.1021/jm3013213  1
2012 Beales P, Jackson PK. Cilia - the prodigal organelle. Cilia. 1: 1. PMID 23351984 DOI: 10.1186/2046-2530-1-1  1
2012 Jackson PK. TTBK2 kinase: linking primary cilia and cerebellar ataxias. Cell. 151: 697-9. PMID 23141531 DOI: 10.1016/j.cell.2012.10.027  1
2012 Maurer T, Garrenton LS, Oh A, Pitts K, Anderson DJ, Skelton NJ, Fauber BP, Pan B, Malek S, Stokoe D, Ludlam MJ, Bowman KK, Wu J, Giannetti AM, Starovasnik MA, ... ... Jackson PK, et al. Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity. Proceedings of the National Academy of Sciences of the United States of America. 109: 5299-304. PMID 22431598 DOI: 10.1073/pnas.1116510109  1
2011 Torres JZ, Summers MK, Peterson D, Brauer MJ, Lee J, Senese S, Gholkar AA, Lo YC, Lei X, Jung K, Anderson DC, Davis DP, Belmont L, Jackson PK. The STARD9/Kif16a kinesin associates with mitotic microtubules and regulates spindle pole assembly. Cell. 147: 1309-23. PMID 22153075 DOI: 10.1016/j.cell.2011.11.020  1
2011 Wright KJ, Baye LM, Olivier-Mason A, Mukhopadhyay S, Sang L, Kwong M, Wang W, Pretorius PR, Sheffield VC, Sengupta P, Slusarski DC, Jackson PK. An ARL3-UNC119-RP2 GTPase cycle targets myristoylated NPHP3 to the primary cilium. Genes & Development. 25: 2347-60. PMID 22085962 DOI: 10.1101/gad.173443.111  1
2011 Anderson DJ, Durieux JK, Song K, Alvarado R, Jackson PK, Hatzivassiliou G, Ludlam MJ. Live-cell microscopy reveals small molecule inhibitor effects on MAPK pathway dynamics. Plos One. 6: e22607. PMID 21829637 DOI: 10.1371/journal.pone.0022607  1
2011 Mukhopadhyay S, Jackson PK. The tubby family proteins. Genome Biology. 12: 225. PMID 21722349 DOI: 10.1186/gb-2011-12-6-225  1
2011 Huang X, Summers MK, Pham V, Lill JR, Liu J, Lee G, Kirkpatrick DS, Jackson PK, Fang G, Dixit VM. Deubiquitinase USP37 is activated by CDK2 to antagonize APC(CDH1) and promote S phase entry. Molecular Cell. 42: 511-23. PMID 21596315 DOI: 10.1016/j.molcel.2011.03.027  1
2011 Sang L, Miller JJ, Corbit KC, Giles RH, Brauer MJ, Otto EA, Baye LM, Wen X, Scales SJ, Kwong M, Huntzicker EG, Sfakianos MK, Sandoval W, Bazan JF, Kulkarni P, ... ... Jackson PK, et al. Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways. Cell. 145: 513-28. PMID 21565611 DOI: 10.1016/j.cell.2011.04.019  1
2011 Jackson PK. Do cilia put brakes on the cell cycle? Nature Cell Biology. 13: 340-2. PMID 21460803 DOI: 10.1038/ncb0411-340  1
2011 Wertz IE, Kusam S, Lam C, Okamoto T, Sandoval W, Anderson DJ, Helgason E, Ernst JA, Eby M, Liu J, Belmont LD, Kaminker JS, O'Rourke KM, Pujara K, Kohli PB, ... ... Jackson PK, et al. Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7. Nature. 471: 110-4. PMID 21368834 DOI: 10.1038/nature09779  1
2011 Westlake CJ, Baye LM, Nachury MV, Wright KJ, Ervin KE, Phu L, Chalouni C, Beck JS, Kirkpatrick DS, Slusarski DC, Sheffield VC, Scheller RH, Jackson PK. Primary cilia membrane assembly is initiated by Rab11 and transport protein particle II (TRAPPII) complex-dependent trafficking of Rabin8 to the centrosome. Proceedings of the National Academy of Sciences of the United States of America. 108: 2759-64. PMID 21273506 DOI: 10.1073/pnas.1018823108  1
2011 Chu CW, Hou F, Zhang J, Phu L, Loktev AV, Kirkpatrick DS, Jackson PK, Zhao Y, Zou H. A novel acetylation of β-tubulin by San modulates microtubule polymerization via down-regulating tubulin incorporation. Molecular Biology of the Cell. 22: 448-56. PMID 21177827 DOI: 10.1091/mbc.E10-03-0203  1
2010 Peart MJ, Poyurovsky MV, Kass EM, Urist M, Verschuren EW, Summers MK, Jackson PK, Prives C. APC/C(Cdc20) targets E2F1 for degradation in prometaphase. Cell Cycle (Georgetown, Tex.). 9: 3956-64. PMID 20948288 DOI: 10.4161/cc.9.19.13162  1
2010 Mukhopadhyay S, Wen X, Chih B, Nelson CD, Lane WS, Scales SJ, Jackson PK. TULP3 bridges the IFT-A complex and membrane phosphoinositides to promote trafficking of G protein-coupled receptors into primary cilia. Genes & Development. 24: 2180-93. PMID 20889716 DOI: 10.1101/gad.1966210  1
2010 Otto EA, Hurd TW, Airik R, Chaki M, Zhou W, Stoetzel C, Patil SB, Levy S, Ghosh AK, Murga-Zamalloa CA, van Reeuwijk J, Letteboer SJ, Sang L, Giles RH, Liu Q, ... ... Jackson PK, et al. Candidate exome capture identifies mutation of SDCCAG8 as the cause of a retinal-renal ciliopathy. Nature Genetics. 42: 840-50. PMID 20835237 DOI: 10.1038/ng.662  1
2010 Peterson D, Lee J, Lei XC, Forrest WF, Davis DP, Jackson PK, Belmont LD. A chemosensitization screen identifies TP53RK, a kinase that restrains apoptosis after mitotic stress. Cancer Research. 70: 6325-35. PMID 20647325 DOI: 10.1158/0008-5472.CAN-10-0015  1
2010 O'Toole JF, Liu Y, Davis EE, Westlake CJ, Attanasio M, Otto EA, Seelow D, Nurnberg G, Becker C, Nuutinen M, Kärppä M, Ignatius J, Uusimaa J, Pakanen S, Jaakkola E, ... ... Jackson PK, ... ... Jackson P, et al. Individuals with mutations in XPNPEP3, which encodes a mitochondrial protein, develop a nephronophthisis-like nephropathy. The Journal of Clinical Investigation. 120: 791-802. PMID 20179356 DOI: 10.1172/JCI40076  1
2010 Torres JZ, Ban KH, Jackson PK. A specific form of phospho protein phosphatase 2 regulates anaphase-promoting complex/cyclosome association with spindle poles. Molecular Biology of the Cell. 21: 897-904. PMID 20089842 DOI: 10.1091/mbc.E09-07-0598  1
2010 O'Toole JF, Liu Y, Davis EE, Westlake CJ, Attanasio M, Otto EA, Seelow D, Nurnberg G, Becker C, Nuutinen M, Kärppä M, Ignatius J, Uusimaa J, Pakanen S, Jaakkola E, ... ... Jackson PK, et al. Individuals with mutations in XPNPEP3, which encodes a mitochondrial protein, develop a nephronophthisis-like nephropathy (Journal of Clinical Investigation (2010) 120, 3 (791-802) DOI: 10.1172/JCI40076) Journal of Clinical Investigation. 120: 1362. DOI: 10.1172/JCI40076C1  1
2009 Jackson PK. Navigating the deubiquitinating proteome with a CompPASS. Cell. 138: 222-4. PMID 19632171 DOI: 10.1016/j.cell.2009.07.008  1
2009 Summers MK, Jackson PK. Biochemical analysis of the Anaphase Promoting Complex: activities of E2 enzymes and substrate competitive (pseudosubstrate) inhibitors. Methods in Molecular Biology (Clifton, N.J.). 545: 313-30. PMID 19475398 DOI: 10.1007/978-1-60327-993-2_20  1
2009 Torres JZ, Miller JJ, Jackson PK. High-throughput generation of tagged stable cell lines for proteomic analysis. Proteomics. 9: 2888-91. PMID 19405035 DOI: 10.1002/pmic.200800873  1
2009 Jackson PK. Navigating the Deubiquitinating Proteome with a ComPASS (DOI:10.1016/j.cell.2009.07.008) Cell. 138: 1247. DOI: 10.1016/j.cell.2009.08.029  1
2008 Loktev AV, Zhang Q, Beck JS, Searby CC, Scheetz TE, Bazan JF, Slusarski DC, Sheffield VC, Jackson PK, Nachury MV. A BBSome subunit links ciliogenesis, microtubule stability, and acetylation. Developmental Cell. 15: 854-65. PMID 19081074 DOI: 10.1016/j.devcel.2008.11.001  1
2008 Summers MK, Pan B, Mukhyala K, Jackson PK. The unique N terminus of the UbcH10 E2 enzyme controls the threshold for APC activation and enhances checkpoint regulation of the APC. Molecular Cell. 31: 544-56. PMID 18722180 DOI: 10.1016/j.molcel.2008.07.014  1
2008 Jackson PK. The hunt for cyclin. Cell. 134: 199-202. PMID 18662532 DOI: 10.1016/j.cell.2008.07.011  1
2008 Tang W, Wu JQ, Guo Y, Hansen DV, Perry JA, Freel CD, Nutt L, Jackson PK, Kornbluth S. Cdc2 and Mos regulate Emi2 stability to promote the meiosis I-meiosis II transition. Molecular Biology of the Cell. 19: 3536-43. PMID 18550795 DOI: 10.1091/mbc.E08-04-0417  1
2008 Jackson PK. Stopping replication, at the beginning. Nature Chemical Biology. 4: 331-2. PMID 18488006 DOI: 10.1038/nchembio0608-331  1
2008 Berdougo E, Nachury MV, Jackson PK, Jallepalli PV. The nucleolar phosphatase Cdc14B is dispensable for chromosome segregation and mitotic exit in human cells. Cell Cycle (Georgetown, Tex.). 7: 1184-90. PMID 18418058  1
2008 Gütgemann I, Lehman NL, Jackson PK, Longacre TA. Emi1 protein accumulation implicates misregulation of the anaphase promoting complex/cyclosome pathway in ovarian clear cell carcinoma. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 21: 445-54. PMID 18204430 DOI: 10.1038/modpathol.3801022  1
2008 Jackson PK. The Hunt for Cyclin (DOI:10.1016/j.cell.2008.07.011) Cell. 135: 366. DOI: 10.1016/j.cell.2008.09.047  1
2007 Wu JQ, Hansen DV, Guo Y, Wang MZ, Tang W, Freel CD, Tung JJ, Jackson PK, Kornbluth S. Control of Emi2 activity and stability through Mos-mediated recruitment of PP2A. Proceedings of the National Academy of Sciences of the United States of America. 104: 16564-9. PMID 17881560 DOI: 10.1073/pnas.0707537104  1
2007 Verschuren EW, Ban KH, Masek MA, Lehman NL, Jackson PK. Loss of Emi1-dependent anaphase-promoting complex/cyclosome inhibition deregulates E2F target expression and elicits DNA damage-induced senescence. Molecular and Cellular Biology. 27: 7955-65. PMID 17875940 DOI: 10.1128/MCB.00908-07  1
2007 Iwai H, Kim M, Yoshikawa Y, Ashida H, Ogawa M, Fujita Y, Muller D, Kirikae T, Jackson PK, Kotani S, Sasakawa C. A bacterial effector targets Mad2L2, an APC inhibitor, to modulate host cell cycling. Cell. 130: 611-23. PMID 17719540 DOI: 10.1016/j.cell.2007.06.043  1
2007 Keck JM, Summers MK, Tedesco D, Ekholm-Reed S, Chuang LC, Jackson PK, Reed SI. Cyclin E overexpression impairs progression through mitosis by inhibiting APC(Cdh1). The Journal of Cell Biology. 178: 371-85. PMID 17664332 DOI: 10.1083/jcb.200703202  1
2007 Ban KH, Torres JZ, Miller JJ, Mikhailov A, Nachury MV, Tung JJ, Rieder CL, Jackson PK. The END network couples spindle pole assembly to inhibition of the anaphase-promoting complex/cyclosome in early mitosis. Developmental Cell. 13: 29-42. PMID 17609108 DOI: 10.1016/j.devcel.2007.04.017  1
2007 Nachury MV, Loktev AV, Zhang Q, Westlake CJ, Peränen J, Merdes A, Slusarski DC, Scheller RH, Bazan JF, Sheffield VC, Jackson PK. A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis. Cell. 129: 1201-13. PMID 17574030 DOI: 10.1016/j.cell.2007.03.053  1
2007 Lehman NL, Tibshirani R, Hsu JY, Natkunam Y, Harris BT, West RB, Masek MA, Montgomery K, van de Rijn M, Jackson PK. Oncogenic regulators and substrates of the anaphase promoting complex/cyclosome are frequently overexpressed in malignant tumors. The American Journal of Pathology. 170: 1793-805. PMID 17456782 DOI: 10.2353/ajpath.2007.060767  1
2007 Tung JJ, Padmanabhan K, Hansen DV, Richter JD, Jackson PK. Translational unmasking of Emi2 directs cytostatic factor arrest in meiosis II. Cell Cycle (Georgetown, Tex.). 6: 725-31. PMID 17361107  1
2007 Hansen DV, Pomerening JR, Summers MK, Miller JJ, Ferrell JE, Jackson PK. Emi2 at the crossroads: where CSF meets MPF. Cell Cycle (Georgetown, Tex.). 6: 732-8. PMID 17361104  1
2007 Wu Q, Guo Y, Yamada A, Perry JA, Wang MZ, Araki M, Freel CD, Tung JJ, Tang W, Margolis SS, Jackson PK, Yamano H, Asano M, Kornbluth S. A role for Cdc2- and PP2A-mediated regulation of Emi2 in the maintenance of CSF arrest. Current Biology : Cb. 17: 213-24. PMID 17276914 DOI: 10.1016/j.cub.2006.12.045  1
2007 Verschuren EW, Jackson PK. Putting transcription repression and protein destruction in pRb's pocket. Developmental Cell. 12: 169-70. PMID 17276331 DOI: 10.1016/j.devcel.2007.01.015  1
2007 Westlake CJ, Junutula JR, Simon GC, Pilli M, Prekeris R, Scheller RH, Jackson PK, Eldridge AG. Identification of Rab11 as a small GTPase binding protein for the Evi5 oncogene. Proceedings of the National Academy of Sciences of the United States of America. 104: 1236-41. PMID 17229837 DOI: 10.1073/pnas.0610500104  1
2007 Marangos P, Verschuren EW, Chen R, Jackson PK, Carroll J. Prophase I arrest and progression to metaphase I in mouse oocytes are controlled by Emi1-dependent regulation of APC(Cdh1). The Journal of Cell Biology. 176: 65-75. PMID 17190794 DOI: 10.1083/jcb.200607070  1
2007 Jackson PK, Peters JM. Cell division, growth and death Current Opinion in Cell Biology. 19: 646-648. DOI: 10.1016/j.ceb.2007.11.001  1
2006 Madgwick S, Hansen DV, Levasseur M, Jackson PK, Jones KT. Mouse Emi2 is required to enter meiosis II by reestablishing cyclin B1 during interkinesis. The Journal of Cell Biology. 174: 791-801. PMID 16966421 DOI: 10.1083/jcb.200604140  1
2006 Miller JJ, Summers MK, Hansen DV, Nachury MV, Lehman NL, Loktev A, Jackson PK. Emi1 stably binds and inhibits the anaphase-promoting complex/cyclosome as a pseudosubstrate inhibitor. Genes & Development. 20: 2410-20. PMID 16921029 DOI: 10.1101/gad.1454006  1
2006 Jackson PK. Developmental neurobiology: a destructive switch for neurons. Nature. 442: 365-6. PMID 16871201 DOI: 10.1038/442365a  1
2006 Lehman NL, Verschuren EW, Hsu JY, Cherry AM, Jackson PK. Overexpression of the anaphase promoting complex/cyclosome inhibitor Emi1 leads to tetraploidy and genomic instability of p53-deficient cells. Cell Cycle (Georgetown, Tex.). 5: 1569-73. PMID 16861914  1
2006 Jackson PK. Climbing the Greatwall to mitosis. Molecular Cell. 22: 156-7. PMID 16630886 DOI: 10.1016/j.molcel.2006.04.005  1
2006 Eldridge AG, Loktev AV, Hansen DV, Verschuren EW, Reimann JD, Jackson PK. The evi5 oncogene regulates cyclin accumulation by stabilizing the anaphase-promoting complex inhibitor emi1. Cell. 124: 367-80. PMID 16439210 DOI: 10.1016/j.cell.2005.10.038  1
2006 Huntzicker EG, Estay IS, Zhen H, Lokteva LA, Jackson PK, Oro AE. Dual degradation signals control Gli protein stability and tumor formation. Genes & Development. 20: 276-81. PMID 16421275 DOI: 10.1101/gad.1380906  1
2006 Hansen DV, Tung JJ, Jackson PK. CaMKII and polo-like kinase 1 sequentially phosphorylate the cytostatic factor Emi2/XErp1 to trigger its destruction and meiotic exit. Proceedings of the National Academy of Sciences of the United States of America. 103: 608-13. PMID 16407128 DOI: 10.1073/pnas.0509549102  1
2006 Eldridge AG, Loktev AV, Hansen DV, Verschuren EW, Reimann JDR, Jackson PK. The Evi5 Oncogene Regulates Cyclin Accumulation by Stabilizing the Anaphase-Promoting Complex Inhibitor Emi1 (DOI:10.1016/j.cell.2005.10.038) Cell. 124: 1301-1302. DOI: 10.1016/j.cell.2006.03.014  1
2005 Lehman NL, van de Rijn M, Jackson PK. Screening of tissue microarrays for ubiquitin proteasome system components in tumors. Methods in Enzymology. 399: 334-55. PMID 16338367 DOI: 10.1016/S0076-6879(05)99023-X  1
2005 Casaletto JB, Nutt LK, Wu Q, Moore JD, Etkin LD, Jackson PK, Hunt T, Kornbluth S. Inhibition of the anaphase-promoting complex by the Xnf7 ubiquitin ligase. The Journal of Cell Biology. 169: 61-71. PMID 15824132 DOI: 10.1083/jcb.200411056  1
2005 Tung JJ, Hansen DV, Ban KH, Loktev AV, Summers MK, Adler JR, Jackson PK. A role for the anaphase-promoting complex inhibitor Emi2/XErp1, a homolog of early mitotic inhibitor 1, in cytostatic factor arrest of Xenopus eggs. Proceedings of the National Academy of Sciences of the United States of America. 102: 4318-23. PMID 15753281 DOI: 10.1073/pnas.0501108102  1
2005 Tung JJ, Jackson PK. Emi1 class of proteins regulate entry into meiosis and the meiosis I to meiosis II transition in Xenopus oocytes. Cell Cycle (Georgetown, Tex.). 4: 478-82. PMID 15701974  1
2004 Baumeister W, Bachmair A, Chau V, Cohen R, Coffino P, Demartino G, Deshaies R, Dohmen J, Emr S, Finley D, Hampton R, Hill C, Hochstrasser M, Huber R, Jackson P, et al. Varshavsky's contributions. Science (New York, N.Y.). 306: 1290-2. PMID 15550643 DOI: 10.1126/science.306.5700.1290  1
2004 Hansen DV, Loktev AV, Ban KH, Jackson PK. Plk1 regulates activation of the anaphase promoting complex by phosphorylating and triggering SCFbetaTrCP-dependent destruction of the APC Inhibitor Emi1. Molecular Biology of the Cell. 15: 5623-34. PMID 15469984 DOI: 10.1091/mbc.E04-07-0598  1
2004 Pagano M, Jackson PK. Wagging the dogma; tissue-specific cell cycle control in the mouse embryo. Cell. 118: 535-8. PMID 15339658 DOI: 10.1016/j.cell.2004.08.013  1
2004 Kaiser BK, Nachury MV, Gardner BE, Jackson PK. Xenopus Cdc14 alpha/beta are localized to the nucleolus and centrosome and are required for embryonic cell division. Bmc Cell Biology. 5: 27. PMID 15251038 DOI: 10.1186/1471-2121-5-27  1
2004 Jackson PK. Linking tumor suppression, DNA damage and the anaphase-promoting complex. Trends in Cell Biology. 14: 331-4. PMID 15246424 DOI: 10.1016/j.tcb.2004.05.005  1
2003 Jackson PK. Can Fizzy fly solo? Nature Cell Biology. 5: 864-5. PMID 14523400 DOI: 10.1038/ncb1003-864  1
2003 He L, Eldridge AG, Jackson PK, Gunn TM, Barsh GS. Accessory proteins for melanocortin signaling: attractin and mahogunin. Annals of the New York Academy of Sciences. 994: 288-98. PMID 12851328  1
2003 Margottin-Goguet F, Hsu JY, Loktev A, Hsieh HM, Reimann JD, Jackson PK. Prophase destruction of Emi1 by the SCF(betaTrCP/Slimb) ubiquitin ligase activates the anaphase promoting complex to allow progression beyond prometaphase. Developmental Cell. 4: 813-26. PMID 12791267 DOI: 10.1016/S1534-5807(03)00153-9  1
2003 Guardavaccaro D, Kudo Y, Boulaire J, Barchi M, Busino L, Donzelli M, Margottin-Goguet F, Jackson PK, Yamasaki L, Pagano M. Control of meiotic and mitotic progression by the F box protein beta-Trcp1 in vivo. Developmental Cell. 4: 799-812. PMID 12791266 DOI: 10.1016/S1534-5807(03)00154-0  1
2003 He L, Lu XY, Jolly AF, Eldridge AG, Watson SJ, Jackson PK, Barsh GS, Gunn TM. Spongiform degeneration in mahoganoid mutant mice. Science (New York, N.Y.). 299: 710-2. PMID 12560552 DOI: 10.1126/science.1079694  1
2003 Jackson PK. Ubiquitinating a phosphorylated Cdk inhibitor on the blades of the Cdc4 beta-propeller. Cell. 112: 142-4. PMID 12553901 DOI: 10.1016/S0092-8674(03)00041-2  1
2002 Borchers AG, Hufton AL, Eldridge AG, Jackson PK, Harland RM, Baker JC. The E3 ubiquitin ligase GREUL1 anteriorizes ectoderm during Xenopus development. Developmental Biology. 251: 395-408. PMID 12435366 DOI: 10.1006/dbio.2002.0814  1
2002 Hansen DV, Hsu JY, Kaiser BK, Jackson PK, Eldridge AG. Control of the centriole and centrosome cycles by ubiquitination enzymes. Oncogene. 21: 6209-21. PMID 12214251 DOI: 10.1038/sj.onc.1205824  1
2002 Kaiser BK, Zimmerman ZA, Charbonneau H, Jackson PK. Disruption of centrosome structure, chromosome segregation, and cytokinesis by misexpression of human Cdc14A phosphatase. Molecular Biology of the Cell. 13: 2289-300. PMID 12134069 DOI: 10.1091/mbc.01-11-0535  1
2002 Jackson PK, Eldridge AG. The SCF ubiquitin ligase: an extended look. Molecular Cell. 9: 923-5. PMID 12049727 DOI: 10.1016/S1097-2765(02)00538-5  1
2002 Hsu JY, Reimann JD, Sørensen CS, Lukas J, Jackson PK. E2F-dependent accumulation of hEmi1 regulates S phase entry by inhibiting APC(Cdh1). Nature Cell Biology. 4: 358-66. PMID 11988738 DOI: 10.1038/ncb785  1
2002 Reimann JD, Jackson PK. Emi1 is required for cytostatic factor arrest in vertebrate eggs. Nature. 416: 850-4. PMID 11976684 DOI: 10.1038/416850a  1
2002 Mailand N, Lukas C, Kaiser BK, Jackson PK, Bartek J, Lukas J. Deregulated human Cdc14A phosphatase disrupts centrosome separation and chromosome segregation. Nature Cell Biology. 4: 317-22. PMID 11901424 DOI: 10.1038/ncb777  1
2001 Reimann JD, Gardner BE, Margottin-Goguet F, Jackson PK. Emi1 regulates the anaphase-promoting complex by a different mechanism than Mad2 proteins. Genes & Development. 15: 3278-85. PMID 11751633 DOI: 10.1101/gad.945701  1
2001 Jackson PK. A new RING for SUMO: wrestling transcriptional responses into nuclear bodies with PIAS family E3 SUMO ligases. Genes & Development. 15: 3053-8. PMID 11731472 DOI: 10.1101/gad.955501  1
2001 Furstenthal L, Swanson C, Kaiser BK, Eldridge AG, Jackson PK. Triggering ubiquitination of a CDK inhibitor at origins of DNA replication. Nature Cell Biology. 3: 715-22. PMID 11483956 DOI: 10.1038/35087026  1
2001 Reimann JD, Freed E, Hsu JY, Kramer ER, Peters JM, Jackson PK. Emi1 is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex. Cell. 105: 645-55. PMID 11389834 DOI: 10.1016/S0092-8674(01)00361-0  1
2001 Furstenthal L, Kaiser BK, Swanson C, Jackson PK. Cyclin E uses Cdc6 as a chromatin-associated receptor required for DNA replication. The Journal of Cell Biology. 152: 1267-78. PMID 11257126 DOI: 10.1083/jcb.152.6.1267  1
2000 Jackson PK, Eldridge AG, Freed E, Furstenthal L, Hsu JY, Kaiser BK, Reimann JD. The lore of the RINGs: substrate recognition and catalysis by ubiquitin ligases. Trends in Cell Biology. 10: 429-39. PMID 10998601 DOI: 10.1016/S0962-8924(00)01834-1  1
2000 Swanson C, Ross J, Jackson PK. Nuclear accumulation of cyclin E/Cdk2 triggers a concentration-dependent switch for the destruction of p27Xic1. Proceedings of the National Academy of Sciences of the United States of America. 97: 7796-801. PMID 10884410 DOI: 10.1073/pnas.97.14.7796  1
1999 Wolf DA, McKeon F, Jackson PK. Budding yeast Cdc6p induces re-replication in fission yeast by inhibition of SCF(Pop)-mediated proteolysis. Molecular & General Genetics : Mgg. 262: 473-80. PMID 10589835 DOI: 10.1007/s004380051108  1
1999 Regan-Reimann JD, Duong QV, Jackson PK. Identification of novel F-box proteins in Xenopus laevis. Current Biology : Cb. 9: R762-3. PMID 10531041 DOI: 10.1016/S0960-9822(00)80006-8  1
1999 Freed E, Lacey KR, Huie P, Lyapina SA, Deshaies RJ, Stearns T, Jackson PK. Components of an SCF ubiquitin ligase localize to the centrosome and regulate the centrosome duplication cycle. Genes & Development. 13: 2242-57. PMID 10485847 DOI: 10.1101/gad.13.17.2242  1
1999 Wolf DA, McKeon F, Jackson PK. F-box/WD-repeat proteins pop1p and Sud1p/Pop2p form complexes that bind and direct the proteolysis of cdc18p. Current Biology : Cb. 9: 373-6. PMID 10209119 DOI: 10.1016/S0960-9822(99)80165-1  1
1999 Lacey KR, Jackson PK, Stearns T. Cyclin-dependent kinase control of centrosome duplication. Proceedings of the National Academy of Sciences of the United States of America. 96: 2817-22. PMID 10077594 DOI: 10.1073/pnas.96.6.2817  1
1998 Wolf DA, Jackson PK. Cell cycle: oiling the gears of anaphase. Current Biology : Cb. 8: R636-9. PMID 9740795  1
1996 Jackson PK. Cell cycle: Cull and destroy Current Biology. 6: 1209-1212. PMID 8939566  1
1996 Wen ST, Jackson PK, Van Etten RA. The cytostatic function of c-Abl is controlled by multiple nuclear localization signals and requires the p53 and Rb tumor suppressor gene products Embo Journal. 15: 1583-1595. PMID 8612582  1
1995 Chen J, Jackson PK, Kirschner MW, Dutta A. Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA. Nature. 374: 386-8. PMID 7885482 DOI: 10.1038/374386a0  1
1995 Mattioni T, Jackson PK, Bchini-Hooft van Huijsduijnen O, Picard D. Cell cycle arrest by tyrosine kinase Abl involves altered early mitogenic response Oncogene. 10: 1325-1333. PMID 7731683  1
1995 Jackson PK, Chevalier S, Philippe M, Kirschner MW. Early events in DNA replication require cyclin E and are blocked by p21CIP1. The Journal of Cell Biology. 130: 755-69. PMID 7642695  1
1994 Van Etten RA, Jackson PK, Baltimore D, Sanders MC, Matsudaira PT, Janmey PA. The COOH terminus of the c-Abl tyrosine kinase contains distinct F- and G-actin binding domains with bundling activity. The Journal of Cell Biology. 124: 325-40. PMID 8294516  0.84
1994 King RW, Jackson PK, Kirschner MW. Mitosis in transition. Cell. 79: 563-71. PMID 7954823 DOI: 10.1016/0092-8674(94)90542-8  1
1993 Jackson PK, Paskind M, Baltimore D. Mutation of a phenylalanine conserved in SH3-containing tyrosine kinases activates the transforming ability of c-Abl. Oncogene. 8: 1943-56. PMID 8510937  0.84
1992 Daley GQ, Van Etten RA, Jackson PK, Bernards A, Baltimore D. Nonmyristoylated Abl proteins transform a factor-dependent hematopoietic cell line. Molecular and Cellular Biology. 12: 1864-71. PMID 1549131  0.84
1992 Mayer BJ, Jackson PK, Van Etten RA, Baltimore D. Point mutations in the abl SH2 domain coordinately impair phosphotyrosine binding in vitro and transforming activity in vivo. Molecular and Cellular Biology. 12: 609-18. PMID 1370711  1
1991 Mayer BJ, Jackson PK, Baltimore D. The noncatalytic src homology region 2 segment of abl tyrosine kinase binds to tyrosine-phosphorylated cellular proteins with high affinity. Proceedings of the National Academy of Sciences of the United States of America. 88: 627-31. PMID 1703304  1
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