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Stephen C. Harrison - Publications

Biological Chemistry and Molecular Pharmacology Harvard University, Cambridge, MA, United States 
structural cell biology

219 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Tomasek D, Rawson S, Lee J, Wzorek JS, Harrison SC, Li Z, Kahne D. Structure of a nascent membrane protein as it folds on the BAM complex. Nature. PMID 32528179 DOI: 10.1038/s41586-020-2370-1  0.6
2020 Fei X, Bell TA, Jenni S, Stinson BM, Baker TA, Harrison SC, Sauer RT. Structures of the ATP-fueled ClpXP proteolytic machine bound to protein substrate. Elife. 9. PMID 32108573 DOI: 10.7554/eLife.52774  0.6
2020 Horwitz JA, Jenni S, Harrison SC, Whelan SPJ. Structure of a rabies virus polymerase complex from electron cryo-microscopy. Proceedings of the National Academy of Sciences of the United States of America. PMID 31953264 DOI: 10.1073/pnas.1918809117  0.6
2020 Pan J, Peng H, Chen B, Harrison SC. Cryo-EM structure of full-length HIV-1 Env bound with the Fab of antibody PG16. Journal of Molecular Biology. PMID 31931014 DOI: 10.1016/j.jmb.2019.11.028  0.76
2020 Jenni S, Bloyet LM, Diaz-Avalos R, Liang B, Whelan SPJ, Grigorieff N, Harrison SC. Structure of the Vesicular Stomatitis Virus L Protein in Complex with Its Phosphoprotein Cofactor. Cell Reports. 30: 53-60.e5. PMID 31914397 DOI: 10.1016/j.celrep.2019.12.024  0.6
2019 McCarthy KR, Raymond DD, Do KT, Schmidt AG, Harrison SC. Affinity maturation in a human humoral response to influenza hemagglutinin. Proceedings of the National Academy of Sciences of the United States of America. PMID 31843892 DOI: 10.1073/pnas.1915620116  0.88
2019 Jenni S, Salgado EN, Herrmann T, Li Z, Grant T, Grigorieff N, Trapani S, Estrozi LF, Harrison SC. In situ Structure of Rotavirus VP1 RNA-Dependent RNA Polymerase. Journal of Molecular Biology. PMID 31233764 DOI: 10.1016/j.jmb.2019.06.016  0.6
2019 Watanabe A, McCarthy KR, Kuraoka M, Schmidt AG, Adachi Y, Onodera T, Tonouchi K, Caradonna TM, Bajic G, Song S, McGee CE, Sempowski GD, Feng F, Urick P, Kepler TB, ... ... Harrison SC, et al. Antibodies to a Conserved Influenza Head Interface Epitope Protect by an IgG Subtype-Dependent Mechanism. Cell. 177: 1124-1135.e16. PMID 31100267 DOI: 10.1016/j.cell.2019.03.048  0.88
2019 Watanabe A, Su KY, Kuraoka M, Yang G, Reynolds AE, Schmidt AG, Harrison SC, Haynes BF, St Clair EW, Kelsoe G. Self-tolerance curtails the B cell repertoire to microbial epitopes. Jci Insight. 4. PMID 31092727 DOI: 10.1172/jci.insight.122551  0.88
2019 Bajic G, van der Poel CE, Kuraoka M, Schmidt AG, Carroll MC, Kelsoe G, Harrison SC. Autoreactivity profiles of influenza hemagglutinin broadly neutralizing antibodies. Scientific Reports. 9: 3492. PMID 30837606 DOI: 10.1038/s41598-019-40175-8  0.88
2019 Schmidt AG, Lee K, Yang PL, Harrison SC. Correction: Small-Molecule Inhibitors of Dengue-Virus Entry. Plos Pathogens. 15: e1007553. PMID 30703168 DOI: 10.1371/journal.ppat.1007553  0.88
2018 Salgado EN, Garcia Rodriguez B, Narayanaswamy N, Krishnan Y, Harrison SC. Visualization of Ca loss from rotavirus during cell entry. Journal of Virology. PMID 30258012 DOI: 10.1128/JVI.01327-18  0.32
2018 Fu Q, Shaik MM, Cai Y, Ghantous F, Piai A, Peng H, Rits-Volloch S, Liu Z, Harrison SC, Seaman MS, Chen B, Chou JJ. Structure of the membrane proximal external region of HIV-1 envelope glycoprotein. Proceedings of the National Academy of Sciences of the United States of America. PMID 30185554 DOI: 10.1073/pnas.1807259115  0.76
2018 Ferdman J, Palladino G, Liao HX, Moody MA, Kepler TB, Del Giudice G, Dormitzer PR, Harrison SC, Settembre EC, Suphaphiphat P. Intra-seasonal antibody repertoire analysis of a subject immunized with an MF59®-adjuvanted pandemic 2009 H1N1 vaccine. Vaccine. PMID 30055967 DOI: 10.1016/j.vaccine.2018.06.054  0.52
2018 Chao LH, Jang J, Johnson A, Nguyen A, Gray N, Yang PL, Harrison SC. How small-molecule inhibitors of dengue-virus infection interfere with viral membrane fusion. Elife. 7. PMID 29999491 DOI: 10.7554/eLife.36461  0.88
2018 Jenni S, Harrison SC. Structure of the DASH/Dam1 complex shows its role at the yeast kinetochore-microtubule interface. Science (New York, N.Y.). 360: 552-558. PMID 29724956 DOI: 10.1126/science.aar6436  0.6
2018 Fera D, Lee MS, Wiehe K, Meyerhoff RR, Piai A, Bonsignori M, Aussedat B, Walkowicz WE, Ton T, Zhou JO, Danishefsky S, Haynes BF, Harrison SC. HIV envelope V3 region mimic embodies key features of a broadly neutralizing antibody lineage epitope. Nature Communications. 9: 1111. PMID 29549260 DOI: 10.1038/s41467-018-03565-6  0.36
2018 McCarthy KR, Watanabe A, Kuraoka M, Do KT, McGee CE, Sempowski GD, Kepler TB, Schmidt AG, Kelsoe G, Harrison SC. Memory B Cells that Cross-React with Group 1 and Group 2 Influenza A Viruses Are Abundant in Adult Human Repertoires. Immunity. 48: 174-184.e9. PMID 29343437 DOI: 10.1016/j.immuni.2017.12.009  0.88
2017 Williams WB, Zhang J, Jiang C, Nicely NI, Fera D, Luo K, Moody MA, Liao HX, Alam SM, Kepler TB, Ramesh A, Wiehe K, Holland JA, Bradley T, Vandergrift N, ... ... Harrison SC, et al. Initiation of HIV neutralizing B cell lineages with sequential envelope immunizations. Nature Communications. 8: 1732. PMID 29170366 DOI: 10.1038/s41467-017-01336-3  0.4
2017 Salgado EN, Upadhyayula S, Harrison SC. Single-particle detection of transcription following rotavirus entry. Journal of Virology. PMID 28701394 DOI: 10.1128/JVI.00651-17  0.32
2017 Liu Y, Pan J, Jenni S, Raymond DD, Caradonna T, Do KT, Schmidt AG, Harrison SC, Grigorieff N. CryoEM structure of an influenza virus receptor-binding site antibody-antigen interface. Journal of Molecular Biology. PMID 28506635 DOI: 10.1016/j.jmb.2017.05.011  0.88
2017 Cai Y, Karaca-Griffin S, Chen J, Tian S, Fredette N, Linton CE, Rits-Volloch S, Lu J, Wagh K, Theiler J, Korber B, Seaman MS, Harrison SC, Carfi A, Chen B. Antigenicity-defined conformations of an extremely neutralization-resistant HIV-1 envelope spike. Proceedings of the National Academy of Sciences of the United States of America. PMID 28396421 DOI: 10.1073/pnas.1700634114  0.76
2017 Bonsignori M, Kreider EF, Fera D, Meyerhoff RR, Bradley T, Wiehe K, Alam SM, Aussedat B, Walkowicz WE, Hwang KK, Saunders KO, Zhang R, Gladden MA, Monroe A, Kumar A, ... ... Harrison SC, et al. Staged induction of HIV-1 glycan-dependent broadly neutralizing antibodies. Science Translational Medicine. 9. PMID 28298420 DOI: 10.1126/scitranslmed.aai7514  0.4
2017 Liu Y, Pan J, Cai Y, Grigorieff N, Harrison SC, Chen B. Conformational states of a soluble, uncleaved HIV-1 envelope trimer. Journal of Virology. PMID 28250125 DOI: 10.1128/JVI.00175-17  0.76
2017 Easterhoff D, Moody MA, Fera D, Cheng H, Ackerman M, Wiehe K, Saunders KO, Pollara J, Vandergrift N, Parks R, Kim J, Michael NL, O'Connell RJ, Excler JL, Robb ML, ... ... Harrison SC, et al. Boosting of HIV envelope CD4 binding site antibodies with long variable heavy third complementarity determining region in the randomized double blind RV305 HIV-1 vaccine trial. Plos Pathogens. 13: e1006182. PMID 28235027 DOI: 10.1371/journal.ppat.1006182  0.4
2016 Kim IS, Jenni S, Stanifer ML, Roth E, Whelan SP, van Oijen AM, Harrison SC. Mechanism of membrane fusion induced by vesicular stomatitis virus G protein. Proceedings of the National Academy of Sciences of the United States of America. PMID 27974607 DOI: 10.1073/pnas.1618883114  0.6
2016 Petrovic A, Keller J, Liu Y, Overlack K, John J, Dimitrova YN, Jenni S, van Gerwen S, Stege P, Wohlgemuth S, Rombaut P, Herzog F, Harrison SC, Vetter IR, Musacchio A. Structure of the MIS12 Complex and Molecular Basis of Its Interaction with CENP-C at Human Kinetochores. Cell. 167: 1028-1040.e15. PMID 27881301 DOI: 10.1016/j.cell.2016.10.005  0.6
2016 Dimitrova YN, Jenni S, Valverde R, Khin Y, Harrison SC. Structure of the MIND Complex Defines a Regulatory Focus for Yeast Kinetochore Assembly. Cell. 167: 1014-1027.e12. PMID 27881300 DOI: 10.1016/j.cell.2016.10.011  0.6
2016 Raymond DD, Stewart SM, Lee J, Ferdman J, Bajic G, Do KT, Ernandes MJ, Suphaphiphat P, Settembre EC, Dormitzer PR, Del Giudice G, Finco O, Kang TH, Ippolito GC, Georgiou G, ... ... Harrison SC, et al. Influenza immunization elicits antibodies specific for an egg-adapted vaccine strain. Nature Medicine. PMID 27820604 DOI: 10.1038/nm.4223  0.88
2016 Corbett KD, Harrison SC. Molecular Architecture of the Yeast Monopolin Complex. Cell Reports. 17: 929. PMID 27732865 DOI: 10.1016/j.celrep.2016.09.070  0.96
2016 Harrison SC. Immunogenic cross-talk between dengue and Zika viruses. Nature Immunology. 17: 1010-2. PMID 27540984 DOI: 10.1038/ni.3539  1
2016 Kuraoka M, Schmidt AG, Nojima T, Feng F, Watanabe A, Kitamura D, Harrison SC, Kepler TB, Kelsoe G. Complex Antigens Drive Permissive Clonal Selection in Germinal Centers. Immunity. PMID 26948373 DOI: 10.1016/j.immuni.2016.02.010  0.88
2016 Meyer PA, Socias S, Key J, Ransey E, Tjon EC, Buschiazzo A, Lei M, Botka C, Withrow J, Neau D, Rajashankar K, Anderson KS, Baxter RH, Blacklow SC, Boggon TJ, ... ... Harrison SC, et al. Data publication with the structural biology data grid supports live analysis. Nature Communications. 7: 10882. PMID 26947396 DOI: 10.1038/ncomms10882  0.32
2015 Bradley T, Fera D, Bhiman J, Eslamizar L, Lu X, Anasti K, Zhang R, Sutherland LL, Scearce RM, Bowman CM, Stolarchuk C, Lloyd KE, Parks R, Eaton A, Foulger A, ... ... Harrison SC, et al. Structural Constraints of Vaccine-Induced Tier-2 Autologous HIV Neutralizing Antibodies Targeting the Receptor-Binding Site. Cell Reports. PMID 26725118 DOI: 10.1016/j.celrep.2015.12.017  0.32
2015 Schmidt AG, Do KT, McCarthy KR, Kepler TB, Liao HX, Moody MA, Haynes BF, Harrison SC. Immunogenic Stimulus for Germline Precursors of Antibodies that Engage the Influenza Hemagglutinin Receptor-Binding Site. Cell Reports. PMID 26711348 DOI: 10.1016/j.celrep.2015.11.063  1
2015 Mahmutovic S, Clark L, Levis SC, Briggiler AM, Enria DA, Harrison SC, Abraham J. Molecular Basis for Antibody-Mediated Neutralization of New World Hemorrhagic Fever Mammarenaviruses. Cell Host & Microbe. 18: 705-713. PMID 26651946 DOI: 10.1016/j.chom.2015.11.005  0.32
2015 Ivanovic T, Harrison SC. Distinct functional determinants of influenza hemagglutinin-mediated membrane fusion. Elife. 4. PMID 26613408 DOI: 10.7554/eLife.11009  0.84
2015 Liang B, Li Z, Jenni S, Rahmeh AA, Morin BM, Grant T, Grigorieff N, Harrison SC, Whelan SP. Structure of the L Protein of Vesicular Stomatitis Virus from Electron Cryomicroscopy. Cell. PMID 26144317 DOI: 10.1016/j.cell.2015.06.018  0.6
2015 Hinshaw SM, Makrantoni V, Kerr A, Marston AL, Harrison SC. Structural evidence for Scc4-dependent localization of cohesin loading. Elife. 4. PMID 26038942 DOI: 10.7554/eLife.06057  1
2015 Chao LH, Klein DE, Schmidt AG, Peña JM, Harrison SC. Correction: Sequential conformational rearrangements in flavivirus membrane fusion. Elife. 4. PMID 25984968 DOI: 10.7554/eLife.08656  0.88
2015 Schmidt AG, Therkelsen MD, Stewart S, Kepler TB, Liao HX, Moody MA, Haynes BF, Harrison SC. Viral receptor-binding site antibodies with diverse germline origins. Cell. 161: 1026-34. PMID 25959776 DOI: 10.1016/j.cell.2015.04.028  1
2015 Harrison SC. Viral membrane fusion. Virology. 479: 498-507. PMID 25866377 DOI: 10.1016/j.virol.2015.03.043  1
2015 Wang Q, Vogan EM, Nocka LM, Rosen CE, Zorn JA, Harrison SC, Kuriyan J. Autoinhibition of Bruton's tyrosine kinase (Btk) and activation by soluble inositol hexakisphosphate. Elife. 4. PMID 25699547 DOI: 10.7554/eLife.06074  1
2015 Xu H, Schmidt AG, O'Donnell T, Therkelsen MD, Kepler TB, Moody MA, Haynes BF, Liao HX, Harrison SC, Shaw DE. Key mutations stabilize antigen-binding conformation during affinity maturation of a broadly neutralizing influenza antibody lineage. Proteins. 83: 771-80. PMID 25524709 DOI: 10.1002/prot.24745  1
2014 Kovacs JM, Noeldeke E, Ha HJ, Peng H, Rits-Volloch S, Harrison SC, Chen B. Stable, uncleaved HIV-1 envelope glycoprotein gp140 forms a tightly folded trimer with a native-like structure. Proceedings of the National Academy of Sciences of the United States of America. 111: 18542-7. PMID 25512514 DOI: 10.1073/pnas.1422269112  0.44
2014 Chao LH, Klein DE, Schmidt AG, Peña JM, Harrison SC. Sequential conformational rearrangements in flavivirus membrane fusion. Elife. 3: e04389. PMID 25479384 DOI: 10.7554/eLife.04389  0.84
2014 Abdelhakim AH, Salgado EN, Fu X, Pasham M, Nicastro D, Kirchhausen T, Harrison SC. Structural correlates of rotavirus cell entry. Plos Pathogens. 10: e1004355. PMID 25211455 DOI: 10.1371/journal.ppat.1004355  1
2014 Fera D, Schmidt AG, Haynes BF, Gao F, Liao HX, Kepler TB, Harrison SC. Affinity maturation in an HIV broadly neutralizing B-cell lineage through reorientation of variable domains. Proceedings of the National Academy of Sciences of the United States of America. 111: 10275-80. PMID 24982157 DOI: 10.1073/pnas.1409954111  1
2014 Kirchhausen T, Owen D, Harrison SC. Molecular structure, function, and dynamics of clathrin-mediated membrane traffic. Cold Spring Harbor Perspectives in Biology. 6: a016725. PMID 24789820 DOI: 10.1101/cshperspect.a016725  1
2013 Hinshaw SM, Harrison SC. An Iml3-Chl4 heterodimer links the core centromere to factors required for accurate chromosome segregation. Cell Reports. 5: 29-36. PMID 24075991 DOI: 10.1016/j.celrep.2013.08.036  1
2013 Bradley DT, Hughes AE, Badger SA, Jones GT, Harrison SC, Wright BJ, Bumpstead S, Baas AF, Grétarsdóttir S, Burnand K, Child AH, Clough RE, Cockerill G, Hafez H, Scott DJ, et al. A variant in LDLR is associated with abdominal aortic aneurysm. Circulation. Cardiovascular Genetics. 6: 498-504. PMID 24046328 DOI: 10.1161/CIRCGENETICS.113.000165  0.4
2013 Patel SD, Ahouidi AD, Bei AK, Dieye TN, Mboup S, Harrison SC, Duraisingh MT. Plasmodium falciparum merozoite surface antigen, PfRH5, elicits detectable levels of invasion-inhibiting antibodies in humans. The Journal of Infectious Diseases. 208: 1679-87. PMID 23904294 DOI: 10.1093/infdis/jit385  1
2013 Earnshaw WC, Allshire RC, Black BE, Bloom K, Brinkley BR, Brown W, Cheeseman IM, Choo KH, Copenhaver GP, Deluca JG, Desai A, Diekmann S, Erhardt S, Fitzgerald-Hayes M, Foltz D, ... ... Harrison SC, et al. Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant. Chromosome Research : An International Journal On the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology. 21: 101-6. PMID 23580138 DOI: 10.1007/s10577-013-9347-y  1
2013 Ivanovic T, Choi JL, Whelan SP, van Oijen AM, Harrison SC. Influenza-virus membrane fusion by cooperative fold-back of stochastically induced hemagglutinin intermediates. Elife. 2: e00333. PMID 23550179 DOI: 10.7554/eLife.00333  1
2013 Klein DE, Choi JL, Harrison SC. Structure of a dengue virus envelope protein late-stage fusion intermediate. Journal of Virology. 87: 2287-93. PMID 23236058 DOI: 10.1128/JVI.02957-12  1
2013 Schmidt AG, Xu H, Khan AR, O'Donnell T, Khurana S, King LR, Manischewitz J, Golding H, Suphaphiphat P, Carfi A, Settembre EC, Dormitzer PR, Kepler TB, Zhang R, Moody MA, ... ... Harrison SC, et al. Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody. Proceedings of the National Academy of Sciences of the United States of America. 110: 264-9. PMID 23175789 DOI: 10.1073/pnas.1218256109  1
2013 Alam SM, Liao HX, Tomaras GD, Bonsignori M, Tsao CY, Hwang KK, Chen H, Lloyd KE, Bowman C, Sutherland L, Jeffries TL, Kozink DM, Stewart S, Anasti K, Jaeger FH, ... ... Harrison SC, et al. Antigenicity and immunogenicity of RV144 vaccine AIDSVAX clade E envelope immunogen is enhanced by a gp120 N-terminal deletion. Journal of Virology. 87: 1554-68. PMID 23175357 DOI: 10.1128/JVI.00718-12  1
2013 Estrozi LF, Settembre EC, Goret G, McClain B, Zhang X, Chen JZ, Grigorieff N, Harrison SC. Location of the dsRNA-dependent polymerase, VP1, in rotavirus particles. Journal of Molecular Biology. 425: 124-32. PMID 23089332 DOI: 10.1016/j.jmb.2012.10.011  1
2012 Campbell MG, Cheng A, Brilot AF, Moeller A, Lyumkis D, Veesler D, Pan J, Harrison SC, Potter CS, Carragher B, Grigorieff N. Movies of ice-embedded particles enhance resolution in electron cryo-microscopy. Structure (London, England : 1993). 20: 1823-8. PMID 23022349 DOI: 10.1016/j.str.2012.08.026  1
2012 Corbett KD, Harrison SC. Molecular architecture of the yeast monopolin complex. Cell Reports. 1: 583-9. PMID 22813733 DOI: 10.1016/j.celrep.2012.05.012  1
2012 Haynes BF, Kelsoe G, Harrison SC, Kepler TB. B-cell-lineage immunogen design in vaccine development with HIV-1 as a case study. Nature Biotechnology. 30: 423-33. PMID 22565972 DOI: 10.1038/nbt.2197  1
2012 Schmidt AG, Lee K, Yang PL, Harrison SC. Small-molecule inhibitors of dengue-virus entry. Plos Pathogens. 8: e1002627. PMID 22496653 DOI: 10.1371/journal.ppat.1002627  1
2012 Ivanovic T, Rozendaal R, Floyd DL, Popovic M, van Oijen AM, Harrison SC. Kinetics of proton transport into influenza virions by the viral M2 channel. Plos One. 7: e31566. PMID 22412838 DOI: 10.1371/journal.pone.0031566  1
2012 Brilot AF, Chen JZ, Cheng A, Pan J, Harrison SC, Potter CS, Carragher B, Henderson R, Grigorieff N. Beam-induced motion of vitrified specimen on holey carbon film. Journal of Structural Biology. 177: 630-7. PMID 22366277 DOI: 10.1016/j.jsb.2012.02.003  1
2012 Schmitzberger F, Harrison SC. RWD domain: a recurring module in kinetochore architecture shown by a Ctf19-Mcm21 complex structure. Embo Reports. 13: 216-22. PMID 22322944 DOI: 10.1038/embor.2012.1  1
2012 Cho US, Harrison SC. Ndc10 is a platform for inner kinetochore assembly in budding yeast. Nature Structural & Molecular Biology. 19: 48-55. PMID 22139014 DOI: 10.1038/nsmb.2178  1
2011 Bown MJ, Jones GT, Harrison SC, Wright BJ, Bumpstead S, Baas AF, Gretarsdottir S, Badger SA, Bradley DT, Burnand K, Child AH, Clough RE, Cockerill G, Hafez H, Scott DJ, et al. Abdominal aortic aneurysm is associated with a variant in low-density lipoprotein receptor-related protein 1. American Journal of Human Genetics. 89: 619-27. PMID 22055160 DOI: 10.1016/j.ajhg.2011.10.002  0.4
2011 Aoki ST, Trask SD, Coulson BS, Greenberg HB, Dormitzer PR, Harrison SC. Cross-linking of rotavirus outer capsid protein VP7 by antibodies or disulfides inhibits viral entry. Journal of Virology. 85: 10509-17. PMID 21849465 DOI: 10.1128/JVI.00234-11  1
2011 Whittle JR, Zhang R, Khurana S, King LR, Manischewitz J, Golding H, Dormitzer PR, Haynes BF, Walter EB, Moody MA, Kepler TB, Liao HX, Harrison SC. Broadly neutralizing human antibody that recognizes the receptor-binding pocket of influenza virus hemagglutinin. Proceedings of the National Academy of Sciences of the United States of America. 108: 14216-21. PMID 21825125 DOI: 10.1073/pnas.1111497108  1
2011 Berardi MJ, Shih WM, Harrison SC, Chou JJ. Mitochondrial uncoupling protein 2 structure determined by NMR molecular fragment searching. Nature. 476: 109-13. PMID 21785437 DOI: 10.1038/nature10257  1
2011 Cho US, Harrison SC. Recognition of the centromere-specific histone Cse4 by the chaperone Scm3. Proceedings of the National Academy of Sciences of the United States of America. 108: 9367-71. PMID 21606327 DOI: 10.1073/pnas.1106389108  1
2011 Grigorieff N, Harrison SC. Near-atomic resolution reconstructions of icosahedral viruses from electron cryo-microscopy. Current Opinion in Structural Biology. 21: 265-73. PMID 21333526 DOI: 10.1016/  1
2011 Böcking T, Aguet F, Harrison SC, Kirchhausen T. Single-molecule analysis of a molecular disassemblase reveals the mechanism of Hsc70-driven clathrin uncoating. Nature Structural & Molecular Biology. 18: 295-301. PMID 21278753 DOI: 10.1038/nsmb.1985  1
2011 Settembre EC, Chen JZ, Dormitzer PR, Grigorieff N, Harrison SC. Atomic model of an infectious rotavirus particle. The Embo Journal. 30: 408-16. PMID 21157433 DOI: 10.1038/emboj.2010.322  1
2011 Cho US, Harrison SC. Reply to Feng et al.: Structures of Scm3-Cse4-H4 complexes Proceedings of the National Academy of Sciences of the United States of America. 108: E597. DOI: 10.1073/pnas.1110503108  1
2010 Cho US, Corbett KD, Al-Bassam J, Bellizzi JJ, De Wulf P, Espelin CW, Miranda JJ, Simons K, Wei RR, Sorger PK, Harrison SC. Molecular structures and interactions in the yeast kinetochore. Cold Spring Harbor Symposia On Quantitative Biology. 75: 395-401. PMID 21467141 DOI: 10.1101/sqb.2010.75.040  1
2010 Harrison SC, Brugge JS. Mechanistic biology in the next quarter century. Molecular Biology of the Cell. 21: 3799-800. PMID 21079017 DOI: 10.1091/mbc.E10-05-0441  0.6
2010 Yu A, Xing Y, Harrison SC, Kirchhausen T. Structural analysis of the interaction between Dishevelled2 and clathrin AP-2 adaptor, a critical step in noncanonical Wnt signaling. Structure (London, England : 1993). 18: 1311-20. PMID 20947020 DOI: 10.1016/j.str.2010.07.010  1
2010 Schmidt AG, Yang PL, Harrison SC. Peptide inhibitors of flavivirus entry derived from the E protein stem. Journal of Virology. 84: 12549-54. PMID 20881042 DOI: 10.1128/JVI.01440-10  1
2010 Guan R, Dai H, Han D, Harrison SC, Kirchhausen T. Structure of the PTEN-like region of auxilin, a detector of clathrin-coated vesicle budding. Structure (London, England : 1993). 18: 1191-8. PMID 20826345 DOI: 10.1016/j.str.2010.06.016  1
2010 Harrison SC. Virology. Looking inside adenovirus. Science (New York, N.Y.). 329: 1026-7. PMID 20798308 DOI: 10.1126/science.1194922  1
2010 Harrison SC, Kirchhausen T. Structural biology: Conservation in vesicle coats. Nature. 466: 1048-9. PMID 20739998 DOI: 10.1038/4661048a  1
2010 Corbett KD, Yip CK, Ee LS, Walz T, Amon A, Harrison SC. The monopolin complex crosslinks kinetochore components to regulate chromosome-microtubule attachments. Cell. 142: 556-67. PMID 20723757 DOI: 10.1016/j.cell.2010.07.017  1
2010 Al-Bassam J, Kim H, Brouhard G, van Oijen A, Harrison SC, Chang F. CLASP promotes microtubule rescue by recruiting tubulin dimers to the microtubule. Developmental Cell. 19: 245-58. PMID 20708587 DOI: 10.1016/j.devcel.2010.07.016  1
2010 Floyd DL, Harrison SC, van Oijen AM. Analysis of kinetic intermediates in single-particle dwell-time distributions. Biophysical Journal. 99: 360-6. PMID 20643053 DOI: 10.1016/j.bpj.2010.04.049  1
2010 Schmidt AG, Yang PL, Harrison SC. Peptide inhibitors of dengue-virus entry target a late-stage fusion intermediate. Plos Pathogens. 6: e1000851. PMID 20386713 DOI: 10.1371/journal.ppat.1000851  1
2010 Kim IS, Trask SD, Babyonyshev M, Dormitzer PR, Harrison SC. Effect of mutations in VP5 hydrophobic loops on rotavirus cell entry. Journal of Virology. 84: 6200-7. PMID 20375171 DOI: 10.1128/JVI.02461-09  1
2010 Wolf M, Garcea RL, Grigorieff N, Harrison SC. Subunit interactions in bovine papillomavirus. Proceedings of the National Academy of Sciences of the United States of America. 107: 6298-303. PMID 20308582 DOI: 10.1073/pnas.0914604107  1
2010 Abraham J, Corbett KD, Farzan M, Choe H, Harrison SC. Structural basis for receptor recognition by New World hemorrhagic fever arenaviruses. Nature Structural & Molecular Biology. 17: 438-44. PMID 20208545 DOI: 10.1038/nsmb.1772  1
2010 McClain B, Settembre E, Temple BR, Bellamy AR, Harrison SC. X-ray crystal structure of the rotavirus inner capsid particle at 3.8 A resolution. Journal of Molecular Biology. 397: 587-99. PMID 20122940 DOI: 10.1016/j.jmb.2010.01.055  1
2010 Xing Y, Böcking T, Wolf M, Grigorieff N, Kirchhausen T, Harrison SC. Structure of clathrin coat with bound Hsc70 and auxilin: mechanism of Hsc70-facilitated disassembly. The Embo Journal. 29: 655-65. PMID 20033059 DOI: 10.1038/emboj.2009.383  1
2010 Trask SD, Kim IS, Harrison SC, Dormitzer PR. A rotavirus spike protein conformational intermediate binds lipid bilayers. Journal of Virology. 84: 1764-70. PMID 20007281 DOI: 10.1128/JVI.01682-09  1
2010 Floyd DL, Otterstrom JJ, Skehel JJ, Harrison SC, Van Oijen AM. Visualizing viral fusion at the single-particle level in microchannels 14th International Conference On Miniaturized Systems For Chemistry and Life Sciences 2010, Microtas 2010. 2: 1412-1414.  1
2010 Schmidt AG, Yang PL, Harrison SC. Peptide inhibitors of dengue-virus entry target a late- stage fusion intermediate Plos Pathogens. 6: 1-11.  1
2009 Alam SM, Morelli M, Dennison SM, Liao HX, Zhang R, Xia SM, Rits-Volloch S, Sun L, Harrison SC, Haynes BF, Chen B. Role of HIV membrane in neutralization by two broadly neutralizing antibodies. Proceedings of the National Academy of Sciences of the United States of America. 106: 20234-9. PMID 19906992 DOI: 10.1073/pnas.0908713106  1
2009 Floyd DL, Harrison SC, van Oijen AM. Method for measurement of viral fusion kinetics at the single particle level. Journal of Visualized Experiments : Jove. PMID 19736545 DOI: 10.3791/1484  1
2009 Yoder JD, Trask SD, Vo TP, Binka M, Feng N, Harrison SC, Greenberg HB, Dormitzer PR. VP5* rearranges when rotavirus uncoats. Journal of Virology. 83: 11372-7. PMID 19692464 DOI: 10.1128/JVI.01228-09  1
2009 Aoki ST, Settembre EC, Trask SD, Greenberg HB, Harrison SC, Dormitzer PR. Structure of rotavirus outer-layer protein VP7 bound with a neutralizing Fab. Science (New York, N.Y.). 324: 1444-7. PMID 19520960 DOI: 10.1126/science.1170481  1
2009 Chen JZ, Settembre EC, Aoki ST, Zhang X, Bellamy AR, Dormitzer PR, Harrison SC, Grigorieff N. Molecular interactions in rotavirus assembly and uncoating seen by high-resolution cryo-EM. Proceedings of the National Academy of Sciences of the United States of America. 106: 10644-8. PMID 19487668 DOI: 10.1073/pnas.0904024106  1
2009 Zhang L, Agosto MA, Ivanovic T, King DS, Nibert ML, Harrison SC. Requirements for the formation of membrane pores by the reovirus myristoylated micro1N peptide. Journal of Virology. 83: 7004-14. PMID 19439475 DOI: 10.1128/JVI.00377-09  1
2008 Lu X, McDonald SM, Tortorici MA, Tao YJ, Vasquez-Del Carpio R, Nibert ML, Patton JT, Harrison SC. Mechanism for coordinated RNA packaging and genome replication by rotavirus polymerase VP1. Structure (London, England : 1993). 16: 1678-88. PMID 19000820 DOI: 10.1016/j.str.2008.09.006  1
2008 Harrison SC. The pH sensor for flavivirus membrane fusion. The Journal of Cell Biology. 183: 177-9. PMID 18936246 DOI: 10.1083/jcb.200809175  1
2008 Floyd DL, Ragains JR, Skehel JJ, Harrison SC, van Oijen AM. Single-particle kinetics of influenza virus membrane fusion. Proceedings of the National Academy of Sciences of the United States of America. 105: 15382-7. PMID 18829437 DOI: 10.1073/pnas.0807771105  1
2008 Cohen RL, Espelin CW, De Wulf P, Sorger PK, Harrison SC, Simons KT. Structural and functional dissection of Mif2p, a conserved DNA-binding kinetochore protein. Molecular Biology of the Cell. 19: 4480-91. PMID 18701705 DOI: 10.1091/mbc.E08-03-0297  1
2008 Harrison SC. Viral membrane fusion. Nature Structural & Molecular Biology. 15: 690-8. PMID 18596815 DOI: 10.1038/nsmb.1456  1
2008 Ivanovic T, Agosto MA, Zhang L, Chandran K, Harrison SC, Nibert ML. Peptides released from reovirus outer capsid form membrane pores that recruit virus particles. The Embo Journal. 27: 1289-98. PMID 18369316 DOI: 10.1038/emboj.2008.60  1
2008 Zhang X, Settembre E, Xu C, Dormitzer PR, Bellamy R, Harrison SC, Grigorieff N. Near-atomic resolution using electron cryomicroscopy and single-particle reconstruction. Proceedings of the National Academy of Sciences of the United States of America. 105: 1867-72. PMID 18238898 DOI: 10.1073/pnas.0711623105  1
2008 Brouhard GJ, Stear JH, Noetzel TL, Al-Bassam J, Kinoshita K, Harrison SC, Howard J, Hyman AA. XMAP215 is a processive microtubule polymerase. Cell. 132: 79-88. PMID 18191222 DOI: 10.1016/j.cell.2007.11.043  1
2008 Hite RK, Gonen T, Harrison SC, Walz T. Interactions of lipids with aquaporin-0 and other membrane proteins. PflüGers Archiv : European Journal of Physiology. 456: 651-61. PMID 17932686 DOI: 10.1007/s00424-007-0353-9  1
2007 Harrison SC. Three-dimensional intricacies in protein-DNA recognition and transcriptional control. Nature Structural & Molecular Biology. 14: 1118-9. PMID 18059448 DOI: 10.1038/nsmb1207-1118  1
2007 Bellizzi JJ, Sorger PK, Harrison SC. Crystal structure of the yeast inner kinetochore subunit Cep3p. Structure (London, England : 1993). 15: 1422-30. PMID 17997968 DOI: 10.1016/j.str.2007.09.008  1
2007 Harrison SC. Comments on the NIGMS PSI. Structure (London, England : 1993). 15: 1344-6. PMID 17997957 DOI: 10.1016/j.str.2007.10.004  1
2007 Kim S, Malinverni JC, Sliz P, Silhavy TJ, Harrison SC, Kahne D. Structure and function of an essential component of the outer membrane protein assembly machine. Science (New York, N.Y.). 317: 961-4. PMID 17702946 DOI: 10.1126/science.1143993  1
2007 Panne D, Maniatis T, Harrison SC. An atomic model of the interferon-beta enhanceosome. Cell. 129: 1111-23. PMID 17574024 DOI: 10.1016/j.cell.2007.05.019  1
2007 Panne D, McWhirter SM, Maniatis T, Harrison SC. Interferon regulatory factor 3 is regulated by a dual phosphorylation-dependent switch. The Journal of Biological Chemistry. 282: 22816-22. PMID 17526488 DOI: 10.1074/jbc.M703019200  1
2007 Li H, Zhang L, Rao A, Harrison SC, Hogan PG. Structure of calcineurin in complex with PVIVIT peptide: portrait of a low-affinity signalling interaction. Journal of Molecular Biology. 369: 1296-306. PMID 17498738 DOI: 10.1016/j.jmb.2007.04.032  1
2007 Miranda JJ, King DS, Harrison SC. Protein arms in the kinetochore-microtubule interface of the yeast DASH complex. Molecular Biology of the Cell. 18: 2503-10. PMID 17460120 DOI: 10.1091/mbc.E07-02-0135  1
2007 Al-Bassam J, Larsen NA, Hyman AA, Harrison SC. Crystal structure of a TOG domain: conserved features of XMAP215/Dis1-family TOG domains and implications for tubulin binding. Structure (London, England : 1993). 15: 355-62. PMID 17355870 DOI: 10.1016/j.str.2007.01.012  1
2007 Larsen NA, Al-Bassam J, Wei RR, Harrison SC. Structural analysis of Bub3 interactions in the mitotic spindle checkpoint. Proceedings of the National Academy of Sciences of the United States of America. 104: 1201-6. PMID 17227844 DOI: 10.1073/pnas.0610358104  1
2007 Wei RR, Al-Bassam J, Harrison SC. The Ndc80/HEC1 complex is a contact point for kinetochore-microtubule attachment. Nature Structural & Molecular Biology. 14: 54-9. PMID 17195848 DOI: 10.1038/nsmb1186  1
2007 Cheng Y, Boll W, Kirchhausen T, Harrison SC, Walz T. Cryo-electron tomography of clathrin-coated vesicles: structural implications for coat assembly. Journal of Molecular Biology. 365: 892-9. PMID 17095010 DOI: 10.1016/j.jmb.2006.10.036  1
2006 Li F, Li W, Farzan M, Harrison SC. Interactions between SARS coronavirus and its receptor. Advances in Experimental Medicine and Biology. 581: 229-34. PMID 17037534 DOI: 10.1007/978-0-387-33012-9_38  1
2006 Rits-Volloch S, Frey G, Harrison SC, Chen B. Restraining the conformation of HIV-1 gp120 by removing a flexible loop. The Embo Journal. 25: 5026-35. PMID 17006538 DOI: 10.1038/sj.emboj.7601358  1
2006 Zhang L, Chandran K, Nibert ML, Harrison SC. Reovirus mu1 structural rearrangements that mediate membrane penetration. Journal of Virology. 80: 12367-76. PMID 17005655 DOI: 10.1128/JVI.01343-06  1
2006 Frey G, Rits-Volloch S, Zhang XQ, Schooley RT, Chen B, Harrison SC. Small molecules that bind the inner core of gp41 and inhibit HIV envelope-mediated fusion. Proceedings of the National Academy of Sciences of the United States of America. 103: 13938-43. PMID 16963566 DOI: 10.1073/pnas.0601036103  1
2006 Fotin A, Kirchhausen T, Grigorieff N, Harrison SC, Walz T, Cheng Y. Structure determination of clathrin coats to subnanometer resolution by single particle cryo-electron microscopy. Journal of Structural Biology. 156: 453-60. PMID 16908193 DOI: 10.1016/j.jsb.2006.07.001  1
2006 Heldwein EE, Lou H, Bender FC, Cohen GH, Eisenberg RJ, Harrison SC. Crystal structure of glycoprotein B from herpes simplex virus 1. Science (New York, N.Y.). 313: 217-20. PMID 16840698 DOI: 10.1126/science.1126548  1
2006 Li F, Berardi M, Li W, Farzan M, Dormitzer PR, Harrison SC. Conformational states of the severe acute respiratory syndrome coronavirus spike protein ectodomain. Journal of Virology. 80: 6794-800. PMID 16809285 DOI: 10.1128/JVI.02744-05  1
2006 Wei RR, Schnell JR, Larsen NA, Sorger PK, Chou JJ, Harrison SC. Structure of a central component of the yeast kinetochore: the Spc24p/Spc25p globular domain. Structure (London, England : 1993). 14: 1003-9. PMID 16765893 DOI: 10.1016/j.str.2006.04.007  1
2006 Al-Bassam J, van Breugel M, Harrison SC, Hyman A. Stu2p binds tubulin and undergoes an open-to-closed conformational change. The Journal of Cell Biology. 172: 1009-22. PMID 16567500 DOI: 10.1083/jcb.200511010  1
2006 Cheng Y, Wolf E, Larvie M, Zak O, Aisen P, Grigorieff N, Harrison SC, Walz T. Single particle reconstructions of the transferrin-transferrin receptor complex obtained with different specimen preparation techniques. Journal of Molecular Biology. 355: 1048-65. PMID 16343539 DOI: 10.1016/j.jmb.2005.11.021  1
2006 Huang IC, Bosch BJ, Li F, Li W, Lee KH, Ghiran S, Vasilieva N, Dermody TS, Harrison SC, Dormitzer PR, Farzan M, Rottier PJ, Choe H. SARS coronavirus, but not human coronavirus NL63, utilizes cathepsin L to infect ACE2-expressing cells. The Journal of Biological Chemistry. 281: 3198-203. PMID 16339146 DOI: 10.1074/jbc.M508381200  1
2005 Cheng Y, Zak O, Aisen P, Harrison SC, Walz T. Single particle reconstruction of the human apo-transferrin-transferrin receptor complex. Journal of Structural Biology. 152: 204-10. PMID 16343946 DOI: 10.1016/j.jsb.2005.10.006  1
2005 Gonen T, Cheng Y, Sliz P, Hiroaki Y, Fujiyoshi Y, Harrison SC, Walz T. Lipid-protein interactions in double-layered two-dimensional AQP0 crystals. Nature. 438: 633-8. PMID 16319884 DOI: 10.1038/nature04321  1
2005 Zhang X, Ji Y, Zhang L, Harrison SC, Marinescu DC, Nibert ML, Baker TS. Features of reovirus outer capsid protein mu1 revealed by electron cryomicroscopy and image reconstruction of the virion at 7.0 Angstrom resolution. Structure (London, England : 1993). 13: 1545-57. PMID 16216585 DOI: 10.1016/j.str.2005.07.012  1
2005 Li F, Li W, Farzan M, Harrison SC. Structure of SARS coronavirus spike receptor-binding domain complexed with receptor. Science (New York, N.Y.). 309: 1864-8. PMID 16166518 DOI: 10.1126/science.1116480  1
2005 Harrison SC. Mechanism of membrane fusion by viral envelope proteins. Advances in Virus Research. 64: 231-61. PMID 16139596 DOI: 10.1016/S0065-3527(05)64007-9  1
2005 Lei M, Robinson MA, Harrison SC. The active conformation of the PAK1 kinase domain. Structure (London, England : 1993). 13: 769-78. PMID 15893667 DOI: 10.1016/j.str.2005.03.007  1
2005 Wei RR, Sorger PK, Harrison SC. Molecular organization of the Ndc80 complex, an essential kinetochore component. Proceedings of the National Academy of Sciences of the United States of America. 102: 5363-7. PMID 15809444 DOI: 10.1073/pnas.0501168102  1
2005 Chen B, Vogan EM, Gong H, Skehel JJ, Wiley DC, Harrison SC. Structure of an unliganded simian immunodeficiency virus gp120 core. Nature. 433: 834-41. PMID 15729334 DOI: 10.1038/nature03327  1
2005 Chen B, Vogan EM, Gong H, Skehel JJ, Wiley DC, Harrison SC. Determining the structure of an unliganded and fully glycosylated SIV gp120 envelope glycoprotein. Structure (London, England : 1993). 13: 197-211. PMID 15698564 DOI: 10.1016/j.str.2004.12.004  1
2005 Miranda JJ, De Wulf P, Sorger PK, Harrison SC. The yeast DASH complex forms closed rings on microtubules. Nature Structural & Molecular Biology. 12: 138-43. PMID 15640796 DOI: 10.1038/nsmb896  1
2005 Modis Y, Ogata S, Clements D, Harrison SC. Variable surface epitopes in the crystal structure of dengue virus type 3 envelope glycoprotein. Journal of Virology. 79: 1223-31. PMID 15613349 DOI: 10.1128/JVI.79.2.1223-1231.2005  1
2004 Larsen NA, Harrison SC. Crystal structure of the spindle assembly checkpoint protein Bub3. Journal of Molecular Biology. 344: 885-92. PMID 15544799 DOI: 10.1016/j.jmb.2004.09.094  1
2004 Arnett KL, Harrison SC, Wiley DC. Crystal structure of a human CD3-epsilon/delta dimer in complex with a UCHT1 single-chain antibody fragment. Proceedings of the National Academy of Sciences of the United States of America. 101: 16268-73. PMID 15534202 DOI: 10.1073/pnas.0407359101  1
2004 Panne D, Maniatis T, Harrison SC. Crystal structure of ATF-2/c-Jun and IRF-3 bound to the interferon-β enhancer Embo Journal. 23: 4384-4393. PMID 15510218 DOI: 10.1038/sj.emboj.7600453  1
2004 Fotin A, Cheng Y, Grigorieff N, Walz T, Harrison SC, Kirchhausen T. Structure of an auxilin-bound clathrin coat and its implications for the mechanism of uncoating. Nature. 432: 649-53. PMID 15502813 DOI: 10.1038/nature03078  1
2004 Fotin A, Cheng Y, Sliz P, Grigorieff N, Harrison SC, Kirchhausen T, Walz T. Molecular model for a complete clathrin lattice from electron cryomicroscopy. Nature. 432: 573-9. PMID 15502812 DOI: 10.1038/nature03079  1
2004 Heldwein EE, Macia E, Wang J, Yin HL, Kirchhausen T, Harrison SC. Crystal structure of the clathrin adaptor protein 1 core. Proceedings of the National Academy of Sciences of the United States of America. 101: 14108-13. PMID 15377783 DOI: 10.1073/pnas.0406102101  1
2004 Dormitzer PR, Nason EB, Prasad BV, Harrison SC. Structural rearrangements in the membrane penetration protein of a non-enveloped virus. Nature. 430: 1053-8. PMID 15329727 DOI: 10.1038/nature02836  1
2004 Lacy DB, Wigelsworth DJ, Melnyk RA, Harrison SC, Collier RJ. Structure of heptameric protective antigen bound to an anthrax toxin receptor: a role for receptor in pH-dependent pore formation. Proceedings of the National Academy of Sciences of the United States of America. 101: 13147-51. PMID 15326297 DOI: 10.1073/pnas.0405405101  1
2004 Harrison SC, Alberts B, Ehrenfeld E, Enquist L, Fineberg H, McKnight SL, Moss B, O'Donnell M, Ploegh H, Schmid SL, Walter KP, Theriot J. Discovery of antivirals against smallpox. Proceedings of the National Academy of Sciences of the United States of America. 101: 11178-92. PMID 15249657 DOI: 10.1073/pnas.0403600101  1
2004 Swalley SE, Baker BM, Calder LJ, Harrison SC, Skehel JJ, Wiley DC. Full-length influenza hemagglutinin HA2 refolds into the trimeric low-pH-induced conformation. Biochemistry. 43: 5902-11. PMID 15134464 DOI: 10.1021/bi049807k  1
2004 Chen B, Cheng Y, Calder L, Harrison SC, Reinherz EL, Skehel JJ, Wiley DC. A chimeric protein of simian immunodeficiency virus envelope glycoprotein gp140 and Escherichia coli aspartate transcarbamoylase. Journal of Virology. 78: 4508-16. PMID 15078931 DOI: 10.1128/JVI.78.9.4508-4516.2004  1
2004 Kim J, Tao Y, Reinisch KM, Harrison SC, Nibert ML. Orthoreovirus and Aquareovirus core proteins: conserved enzymatic surfaces, but not protein-protein interfaces. Virus Research. 101: 15-28. PMID 15010214 DOI: 10.1016/j.virusres.2003.12.003  1
2004 Cheng Y, Zak O, Aisen P, Harrison SC, Walz T. Structure of the human transferrin receptor-transferrin complex. Cell. 116: 565-76. PMID 14980223 DOI: 10.1016/S0092-8674(04)00130-8  1
2004 Modis Y, Ogata S, Clements D, Harrison SC. Structure of the dengue virus envelope protein after membrane fusion. Nature. 427: 313-9. PMID 14737159 DOI: 10.1038/nature02165  1
2004 Harrison SC. Whither structural biology? Nature Structural & Molecular Biology. 11: 12-5. PMID 14718917 DOI: 10.1038/nsmb0104-12  1
2004 Van den Berg B, Clemons WM, Collinson I, Modis Y, Hartmann E, Harrison SC, Rapoport TA. X-ray structure of a protein-conducting channel. Nature. 427: 36-44. PMID 14661030 DOI: 10.1038/nature02218  1
2003 Allison SL, Tao YJ, O'Riordain G, Mandl CW, Harrison SC, Heinz FX. Two distinct size classes of immature and mature subviral particles from tick-borne encephalitis virus. Journal of Virology. 77: 11357-66. PMID 14557621 DOI: 10.1128/JVI.77.21.11357-11366.2003  1
2003 Espelin CW, Simons KT, Harrison SC, Sorger PK. Binding of the essential Saccharomyces cerevisiae kinetochore protein Ndc10p to CDEII. Molecular Biology of the Cell. 14: 4557-68. PMID 13679521 DOI: 10.1091/mbc.E02-08-0533  1
2003 Jin L, Sliz P, Chen L, Macián F, Rao A, Hogan PG, Harrison SC. An asymmetric NFAT1 dimer on a pseudo-palindromic kappa B-like DNA site. Nature Structural Biology. 10: 807-11. PMID 12949491 DOI: 10.1038/nsb975  1
2003 Odegard AL, Chandran K, Liemann S, Harrison SC, Nibert ML. Disulfide bonding among micro 1 trimers in mammalian reovirus outer capsid: a late and reversible step in virion morphogenesis. Journal of Virology. 77: 5389-400. PMID 12692241 DOI: 10.1128/JVI.77.9.5389-5400.2003  1
2003 Sliz P, Harrison SC, Rosenbaum G. How does radiation damage in protein crystals depend on X-ray dose? Structure (London, England : 1993). 11: 13-9. PMID 12517336 DOI: 10.1016/S0969-2126(02)00910-3  1
2002 Tao Y, Farsetta DL, Nibert ML, Harrison SC. RNA synthesis in a cage--structural studies of reovirus polymerase lambda3. Cell. 111: 733-45. PMID 12464184 DOI: 10.1016/S0092-8674(02)01110-8  1
2002 Dormitzer PR, Sun ZY, Blixt O, Paulson JC, Wagner G, Harrison SC. Specificity and affinity of sialic acid binding by the rhesus rotavirus VP8* core. Journal of Virology. 76: 10512-7. PMID 12239329 DOI: 10.1128/JVI.76.20.10512-10517.2002  1
2002 Dormitzer PR, Sun ZY, Wagner G, Harrison SC. The rhesus rotavirus VP4 sialic acid binding domain has a galectin fold with a novel carbohydrate binding site. The Embo Journal. 21: 885-97. PMID 11867517 DOI: 10.1093/emboj/21.5.885  0.52
2002 Liemann S, Chandran K, Baker TS, Nibert ML, Harrison SC. Structure of the reovirus membrane-penetration protein, Mu1, in a complex with is protector protein, Sigma3. Cell. 108: 283-95. PMID 11832217 DOI: 10.1016/S0092-8674(02)00612-8  1
2002 Parrini MC, Lei M, Harrison SC, Mayer BJ. Pak1 kinase homodimers are autoinhibited in trans and dissociated upon activation by Cdc42 and Rac1. Molecular Cell. 9: 73-83. PMID 11804587 DOI: 10.1016/S1097-2765(01)00428-2  1
2001 Olland AM, Jané-Valbuena J, Schiff LA, Nibert ML, Harrison SC. Structure of the reovirus outer capsid and dsRNA-binding protein sigma3 at 1.8 A resolution. The Embo Journal. 20: 979-89. PMID 11230122 DOI: 10.1093/emboj/20.5.979  1
2000 Zhou G, Ferrer M, Chopra R, Kapoor TM, Strassmaier T, Weissenhorn W, Skehel JJ, Oprian D, Schreiber SL, Harrison SC, Wiley DC. The structure of an HIV-1 specific cell entry inhibitor in complex with the HIV-1 gp41 trimeric core. Bioorganic & Medicinal Chemistry. 8: 2219-27. PMID 11026535 DOI: 10.1016/S0968-0896(00)00155-3  1
2000 Lei M, Lu W, Meng W, Parrini MC, Eck MJ, Mayer BJ, Harrison SC. Structure of PAK1 in an autoinhibited conformation reveals a multistage activation switch. Cell. 102: 387-97. PMID 10975528  1
2000 Chen B, Zhou G, Kim M, Chishti Y, Hussey RE, Ely B, Skehel JJ, Reinherz EL, Harrison SC, Wiley DC. Expression, purification, and characterization of gp160e, the soluble, trimeric ectodomain of the simian immunodeficiency virus envelope glycoprotein, gp160. The Journal of Biological Chemistry. 275: 34946-53. PMID 10944528 DOI: 10.1074/jbc.M004905200  1
2000 ter Haar E, Harrison SC, Kirchhausen T. Peptide-in-groove interactions link target proteins to the beta-propeller of clathrin. Proceedings of the National Academy of Sciences of the United States of America. 97: 1096-100. PMID 10655490 DOI: 10.1073/pnas.97.3.1096  1
1999 Ferrer M, Kapoor TM, Strassmaier T, Weissenhorn W, Skehel JJ, Oprian D, Schreiber SL, Wiley DC, Harrison SC. Selection of gp41-mediated HIV-1 cell entry inhibitors from biased combinatorial libraries of non-natural binding elements. Nature Structural Biology. 6: 953-60. PMID 10504731 DOI: 10.1038/13324  1
1999 Musacchio A, Smith CJ, Roseman AM, Harrison SC, Kirchhausen T, Pearse BM. Functional organization of clathrin in coats: combining electron cryomicroscopy and X-ray crystallography. Molecular Cell. 3: 761-70. PMID 10394364 DOI: 10.1016/S1097-2765(01)80008-3  1
1999 Xu W, Doshi A, Lei M, Eck MJ, Harrison SC. Crystal structures of c-Src reveal features of its autoinhibitory mechanism. Molecular Cell. 3: 629-38. PMID 10360179 DOI: 10.1016/S1097-2765(00)80356-1  1
1999 Weissenhorn W, Dessen A, Calder LJ, Harrison SC, Skehel JJ, Wiley DC. Structural basis for membrane fusion by enveloped viruses. Molecular Membrane Biology. 16: 3-9. PMID 10332732  1
1998 ter Haar E, Musacchio A, Harrison SC, Kirchhausen T. Atomic structure of clathrin: a beta propeller terminal domain joins an alpha zigzag linker. Cell. 95: 563-73. PMID 9827808 DOI: 10.1016/S0092-8674(00)81623-2  1
1998 Huse M, Eck MJ, Harrison SC. A Zn2+ ion links the cytoplasmic tail of CD4 and the N-terminal region of Lck. The Journal of Biological Chemistry. 273: 18729-33. PMID 9668045 DOI: 10.1074/jbc.273.30.18729  1
1998 Berger JM, Fass D, Wang JC, Harrison SC. Structural similarities between topoisomerases that cleave one or both DNA strands. Proceedings of the National Academy of Sciences of the United States of America. 95: 7876-81. PMID 9653108 DOI: 10.1073/pnas.95.14.7876  1
1997 Weissenhorn W, Dessen A, Harrison SC, Skehel JJ, Wiley DC. Atomic structure of the ectodomain from HIV-1 gp41. Nature. 387: 426-30. PMID 9163431 DOI: 10.1038/387426a0  1
1997 Xu W, Harrison SC, Eck MJ. Three-dimensional structure of the tyrosine kinase c-Src. Nature. 385: 595-602. PMID 9024657 DOI: 10.1038/385595a0  1
1996 Weissenhorn W, Eck MJ, Harrison SC, Wiley DC. Phosphorylated T cell receptor zeta-chain and ZAP70 tandem SH2 domains form a 1:3 complex in vitro. European Journal of Biochemistry / Febs. 238: 440-5. PMID 8681956  1
1996 Liang SD, Marmorstein R, Harrison SC, Ptashne M. DNA sequence preferences of GAL4 and PPR1: how a subset of Zn2 Cys6 binuclear cluster proteins recognizes DNA. Molecular and Cellular Biology. 16: 3773-80. PMID 8668194  1
1996 Roca J, Berger JM, Harrison SC, Wang JC. DNA transport by a type II topoisomerase: direct evidence for a two-gate mechanism. Proceedings of the National Academy of Sciences of the United States of America. 93: 4057-62. PMID 8633016 DOI: 10.1073/pnas.93.9.4057  1
1996 Nolte RT, Eck MJ, Schlessinger J, Shoelson SE, Harrison SC. Crystal structure of the PI 3-kinase p85 amino-terminal SH2 domain and its phosphopeptide complexes. Nature Structural Biology. 3: 364-74. PMID 8599763  1
1996 Eck MJ, Pluskey S, Trüb T, Harrison SC, Shoelson SE. Spatial constraints on the recognition of phosphoproteins by the tandem SH2 domains of the phosphatase SH-PTP2. Nature. 379: 277-80. PMID 8538796 DOI: 10.1038/379277a0  1
1996 Berger JM, Gamblin SJ, Harrison SC, Wang JC. Structure and mechanism of DNA topoisomerase II. Nature. 379: 225-32. PMID 8538787 DOI: 10.1038/379225a0  1
1995 Songyang Z, Carraway KL, Eck MJ, Harrison SC, Feldman RA, Mohammadi M, Schlessinger J, Hubbard SR, Smith DP, Eng C. Catalytic specificity of protein-tyrosine kinases is critical for selective signalling. Nature. 373: 536-9. PMID 7845468 DOI: 10.1038/373536a0  1
1994 Marmorstein R, Harrison SC. Crystal structure of a PPR1-DNA complex: DNA recognition by proteins containing a Zn2Cys6 binuclear cluster. Genes & Development. 8: 2504-12. PMID 7958913  1
1994 Eck MJ, Atwell SK, Shoelson SE, Harrison SC. Structure of the regulatory domains of the Src-family tyrosine kinase Lck. Nature. 368: 764-9. PMID 7512222 DOI: 10.1038/368764a0  1
1993 Eck MJ, Shoelson SE, Harrison SC. Recognition of a high-affinity phosphotyrosyl peptide by the Src homology-2 domain of p56lck. Nature. 362: 87-91. PMID 7680435 DOI: 10.1038/362087a0  1
1992 Baleja JD, Marmorstein R, Harrison SC, Wagner G. Solution structure of the DNA-binding domain of Cd2-GAL4 from S. cerevisiae. Nature. 356: 450-3. PMID 1557130 DOI: 10.1038/356450a0  1
1992 Marmorstein R, Carey M, Ptashne M, Harrison SC. DNA recognition by GAL4: structure of a protein-DNA complex. Nature. 356: 408-14. PMID 1557122 DOI: 10.1038/356408a0  1
1991 Mondragón A, Harrison SC. The phage 434 Cro/OR1 complex at 2.5 A resolution. Journal of Molecular Biology. 219: 321-34. PMID 2038059 DOI: 10.1016/0022-2836(91)90568-Q  1
1990 Pabo CO, Aggarwal AK, Jordan SR, Beamer LJ, Obeysekare UR, Harrison SC. Conserved residues make similar contacts in two repressor-operator complexes. Science (New York, N.Y.). 247: 1210-3. PMID 2315694 DOI: 10.1126/science.2315694  1
1989 Mondragón A, Subbiah S, Almo SC, Drottar M, Harrison SC. Structure of the amino-terminal domain of phage 434 repressor at 2.0 A resolution. Journal of Molecular Biology. 205: 189-200. PMID 2926803 DOI: 10.1016/0022-2836(89)90375-6  1
1989 Mondragón A, Wolberger C, Harrison SC. Structure of phage 434 Cro protein at 2.35 A resolution. Journal of Molecular Biology. 205: 179-88. PMID 2647998 DOI: 10.1016/0022-2836(89)90374-4  1
1988 Harrison SC, Anderson JE, Koudelka GB, Mondragon A, Subbiah S, Wharton RP, Wolberger C, Ptashne M. Recognition of DNA sequences by the repressor of bacteriophage 434. Biophysical Chemistry. 29: 31-7. PMID 3359001 DOI: 10.1016/0301-4622(88)87022-4  1
1988 Wolberger C, Dong YC, Ptashne M, Harrison SC. Structure of a phage 434 Cro/DNA complex. Nature. 335: 789-95. PMID 3185709 DOI: 10.1038/335789a0  1
1987 Wolberger C, Harrison SC. Crystallization and X-ray diffraction studies of a 434 Cro-DNA complex. Journal of Molecular Biology. 196: 951-4. PMID 3681985 DOI: 10.1016/0022-2836(87)90419-0  1
1987 Kirchhausen T, Scarmato P, Harrison SC, Monroe JJ, Chow EP, Mattaliano RJ, Ramachandran KL, Smart JE, Ahn AH, Brosius J. Clathrin light chains LCA and LCB are similar, polymorphic, and share repeated heptad motifs. Science (New York, N.Y.). 236: 320-4. PMID 3563513 DOI: 10.1126/science.3563513  1
1987 Kirchhausen T, Harrison SC, Chow EP, Mattaliano RJ, Ramachandran KL, Smart J, Brosius J. Clathrin heavy chain: molecular cloning and complete primary structure. Proceedings of the National Academy of Sciences of the United States of America. 84: 8805-9. PMID 3480512  1
1986 Hogle JM, Maeda A, Harrison SC. Structure and assembly of turnip crinkle virus. I. X-ray crystallographic structure analysis at 3.2 A resolution. Journal of Molecular Biology. 191: 625-38. PMID 3806676 DOI: 10.1016/0022-2836(86)90450-X  1
1986 Kirchhausen T, Harrison SC, Heuser J. Configuration of clathrin trimers: evidence from electron microscopy. Journal of Ultrastructure and Molecular Structure Research. 94: 199-208. PMID 3805786 DOI: 10.1016/0889-1605(86)90067-4  1
1986 Durbin RM, Burns R, Moulai J, Metcalf P, Freymann D, Blum M, Anderson JE, Harrison SC, Wiley DC. Protein, DNA, and virus crystallography with a focused imaging proportional counter. Science (New York, N.Y.). 232: 1127-32. PMID 3704639  1
1985 Harrison SC, Winkler FK, Schutt CE, Durbin RM. Diffraction methods for biological macromolecules. Oscillation method with large unit cells. Methods in Enzymology. 114: 211-37. PMID 4079768 DOI: 10.1016/0076-6879(85)14021-8  1
1985 Kirchhausen T, Wang JC, Harrison SC. DNA gyrase and its complexes with DNA: direct observation by electron microscopy. Cell. 41: 933-43. PMID 2988794 DOI: 10.1016/S0092-8674(85)80074-X  1
1984 Kirchhausen T, Harrison SC. Structural domains of clathrin heavy chains. The Journal of Cell Biology. 99: 1725-34. PMID 6386825  1
1983 Olson AJ, Bricogne G, Harrison SC. Structure of tomato busy stunt virus IV. The virus particle at 2.9 A resolution. Journal of Molecular Biology. 171: 61-93. PMID 6644820 DOI: 10.1016/S0022-2836(83)80314-3  1
1983 Hogle J, Kirchhausen T, Harrison SC. Divalent cation sites in tomato bushy stunt virus. Difference maps at 2-9 A resolution. Journal of Molecular Biology. 171: 95-100. PMID 6417343 DOI: 10.1016/S0022-2836(83)80315-5  1
1983 Kirchhausen T, Harrison SC, Parham P, Brodsky FM. Location and distribution of the light chains in clathrin trimers. Proceedings of the National Academy of Sciences of the United States of America. 80: 2481-5. PMID 6189124  1
1983 Harrison SC, Kirchhausen T. Clathrin, cages, and coated vesicles. Cell. 33: 650-2. PMID 6135512  1
1981 Kirchhausen T, Harrison SC. Protein organization in clathrin trimers. Cell. 23: 755-61. PMID 7226229 DOI: 10.1016/0092-8674(81)90439-6  1
1978 Harrison SC, Olson AJ, Schutt CE, Winkler FK, Bricogne G. Tomato bushy stunt virus at 2.9 A resolution. Nature. 276: 368-73. PMID 19711552 DOI: 10.1038/276368a0  1
1977 Winkler FK, Schutt CE, Harrison SC, Bricogne G. Tomato bushy stunt virus at 5.5-A resolution. Nature. 265: 509-13. PMID 834302  1
1974 Harrison SC, Jack A, Goodenough D, Sefton BM. Structural studies of spherical viruses. Journal of Supramolecular Structure. 2: 486-95. PMID 4437182 DOI: 10.1002/jss.400020233  1
1971 Harrison SC, Caspar DL, Camerini-Otero RD, Franklin RM. Lipid and protein arrangement in bacteriophage PM2. Nature: New Biology. 229: 197-201. PMID 5281012  1
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