Cynthia Wolberger - Publications

Johns Hopkins University, Baltimore, MD 
ubiquitination and acetylation, transcription, x-ray crystallography, cryo-EM, biophysical methods

112 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Worden EJ, Zhang X, Wolberger C. Structural basis for COMPASS recognition of an H2B-ubiquitinated nucleosome. Elife. 9. PMID 31922488 DOI: 10.7554/eLife.53199  1
2019 Morgan M, Jbara M, Brik A, Wolberger C. Semisynthesis of ubiquitinated histone H2B with a native or nonhydrolyzable linkage. Methods in Enzymology. 618: 1-27. PMID 30850047 DOI: 10.1016/bs.mie.2019.01.003  1
2019 Nune M, Morgan MT, Connell Z, McCullough L, Jbara M, Sun H, Brik A, Formosa T, Wolberger C. FACT and Ubp10 collaborate to modulate H2B deubiquitination and nucleosome dynamics. Elife. 8. PMID 30681413 DOI: 10.7554/eLife.40988  1
2018 Jbara M, Laps S, Morgan M, Kamnesky G, Mann G, Wolberger C, Brik A. Palladium prompted on-demand cysteine chemistry for the synthesis of challenging and uniquely modified proteins. Nature Communications. 9: 3154. PMID 30089783 DOI: 10.1038/s41467-018-05628-0  1
2018 Bhat S, Hwang Y, Gibson MD, Morgan MT, Taverna SD, Zhao Y, Wolberger C, Poirier MG, Cole PA. Hydrazide Mimics for Protein Lysine Acylation to Assess Nucleosome Dynamics and Deubiquitinase Action. Journal of the American Chemical Society. PMID 29991262 DOI: 10.1021/jacs.8b03572  1
2017 Brickner JR, Soll JM, Lombardi PM, Vågbø CB, Mudge MC, Oyeniran C, Rabe R, Jackson J, Sullender ME, Blazosky E, Byrum AK, Zhao Y, Corbett MA, Gécz J, Field M, ... ... Wolberger C, et al. A ubiquitin-dependent signalling axis specific for ALKBH-mediated DNA dealkylation repair. Nature. 551: 389-393. PMID 29144457 DOI: 10.1038/nature24484  1
2017 Lombardi PM, Matunis MJ, Wolberger C. RAP80, ubiquitin and SUMO in the DNA damage response. Journal of Molecular Medicine (Berlin, Germany). PMID 28681078 DOI: 10.1007/s00109-017-1561-1  0.24
2017 Bondalapati S, Eid E, Mali SM, Wolberger C, Brik A. Total chemical synthesis of SUMO-2-Lys63-linked diubiquitin hybrid chains assisted by removable solubilizing tags. Chemical Science. 8: 4027-4034. PMID 28580118 DOI: 10.1039/c7sc00488e  1
2017 Chen Z, Jiang H, Xu W, Li X, Dempsey DR, Zhang X, Devreotes P, Wolberger C, Amzel LM, Gabelli SB, Cole PA. A Tunable Brake for HECT Ubiquitin Ligases. Molecular Cell. 66: 345-357.e6. PMID 28475870 DOI: 10.1016/j.molcel.2017.03.020  1
2017 Ondracek CR, Frappier V, Ringel AE, Wolberger C, Guarente L. Mutations that Allow SIR2 Orthologs to Function in a NAD(+)-Depleted Environment. Cell Reports. 18: 2310-2319. PMID 28273448 DOI: 10.1016/j.celrep.2017.02.031  1
2016 DiBello A, Datta AB, Zhang X, Wolberger C. Role of E2- RING interactions in governing RNF4-mediated substrate ubiquitination. Journal of Molecular Biology. PMID 27678051 DOI: 10.1016/j.jmb.2016.09.018  1
2016 Ringel AE, Wolberger C. Structural basis for acyl-group discrimination by human Gcn5L2. Acta Crystallographica. Section D, Structural Biology. 72: 841-848. PMID 27377381 DOI: 10.1107/S2059798316007907  1
2016 Chen Z, Thomas SN, Bolduc DM, Jiang X, Zhang X, Wolberger C, Cole PA. Enzymatic Analysis of PTEN Ubiquitylation by WWP2 and NEDD4-1 E3 ligases. Biochemistry. PMID 27295432 DOI: 10.1021/acs.biochem.6b00448  1
2016 Berg JM, Bhalla N, Bourne PE, Chalfie M, Drubin DG, Fraser JS, Greider CW, Hendricks M, Jones C, Kiley R, King S, Kirschner MW, Krumholz HM, Lehmann R, Leptin M, ... ... Wolberger C, et al. Preprints for the life sciences. Science (New York, N.Y.). 352: 899-901. PMID 27199406 DOI: 10.1126/science.aaf9133  1
2016 Bheda P, Jing H, Wolberger C, Lin H. The Substrate Specificity of Sirtuins. Annual Review of Biochemistry. PMID 27088879 DOI: 10.1146/annurev-biochem-060815-014537  1
2016 Jbara M, Maity SK, Morgan M, Wolberger C, Brik A. Chemical Synthesis of Phosphorylated Histone H2A at Tyr57 Reveals Insight into the Inhibition Mode of the SAGA Deubiquitinating Module. Angewandte Chemie (International Ed. in English). PMID 26960207 DOI: 10.1002/anie.201600638  1
2016 Morgan MT, Haj-Yahya M, Ringel AE, Bandi P, Brik A, Wolberger C. Structural basis for histone H2B deubiquitination by the SAGA DUB module. Science (New York, N.Y.). 351: 725-8. PMID 26912860 DOI: 10.1126/science.aac5681  1
2015 Ringel AE, Cieniewicz AM, Taverna SD, Wolberger C. Nucleosome competition reveals processive acetylation by the SAGA HAT module. Proceedings of the National Academy of Sciences of the United States of America. 112: E5461-70. PMID 26401015 DOI: 10.1073/pnas.1508449112  1
2015 Kumar P, Magala P, Geiger-Schuller KR, Majumdar A, Tolman JR, Wolberger C. Role of a non-canonical surface of Rad6 in ubiquitin conjugating activity. Nucleic Acids Research. PMID 26286193 DOI: 10.1093/nar/gkv845  1
2015 Zhao H, Ghirlando R, Alfonso C, Arisaka F, Attali I, Bain DL, Bakhtina MM, Becker DF, Bedwell GJ, Bekdemir A, Besong TM, Birck C, Brautigam CA, Brennerman W, Byron O, ... ... Wolberger C, et al. A multilaboratory comparison of calibration accuracy and the performance of external references in analytical ultracentrifugation. Plos One. 10: e0126420. PMID 25997164 DOI: 10.1371/journal.pone.0126420  0.4
2015 Kumar P, Wolberger C. Structure of the yeast Bre1 RING domain. Proteins. 83: 1185-90. PMID 25864391 DOI: 10.1002/prot.24812  1
2015 Yan M, Wolberger C. Uncovering the role of Sgf73 in maintaining SAGA deubiquitinating module structure and activity. Journal of Molecular Biology. 427: 1765-78. PMID 25526805 DOI: 10.1016/j.jmb.2014.12.004  1
2015 Audrito V, Serra S, Brusa D, Mazzola F, Arruga F, Vaisitti T, Coscia M, Maffei R, Rossi D, Wang T, Inghirami G, Rizzi M, Gaidano G, Garcia JG, Wolberger C, et al. Extracellular nicotinamide phosphoribosyltransferase (NAMPT) promotes M2 macrophage polarization in chronic lymphocytic leukemia. Blood. 125: 111-23. PMID 25368373 DOI: 10.1182/blood-2014-07-589069  1
2014 Ringel AE, Roman C, Wolberger C. Alternate deacylating specificities of the archaeal sirtuins Sir2Af1 and Sir2Af2. Protein Science : a Publication of the Protein Society. 23: 1686-97. PMID 25200501 DOI: 10.1002/pro.2546  1
2014 Guzzo CM, Ringel A, Cox E, Uzoma I, Zhu H, Blackshaw S, Wolberger C, Matunis MJ. Characterization of the SUMO-binding activity of the myeloproliferative and mental retardation (MYM)-type zinc fingers in ZNF261 and ZNF198. Plos One. 9: e105271. PMID 25133527 DOI: 10.1371/journal.pone.0105271  1
2014 Cieniewicz AM, Moreland L, Ringel AE, Mackintosh SG, Raman A, Gilbert TM, Wolberger C, Tackett AJ, Taverna SD. The bromodomain of Gcn5 regulates site specificity of lysine acetylation on histone H3. Molecular & Cellular Proteomics : McP. 13: 2896-910. PMID 25106422 DOI: 10.1074/mcp.M114.038174  1
2014 Berndsen CE, Wolberger C. New insights into ubiquitin E3 ligase mechanism. Nature Structural & Molecular Biology. 21: 301-7. PMID 24699078 DOI: 10.1038/nsmb.2780  1
2014 Wolberger C. Mechanisms for regulating deubiquitinating enzymes. Protein Science : a Publication of the Protein Society. 23: 344-53. PMID 24403057 DOI: 10.1002/pro.2415  1
2013 Taylor MS, Ruch TR, Hsiao PY, Hwang Y, Zhang P, Dai L, Huang CR, Berndsen CE, Kim MS, Pandey A, Wolberger C, Marmorstein R, Machamer C, Boeke JD, Cole PA. Architectural organization of the metabolic regulatory enzyme ghrelin O-acyltransferase. The Journal of Biological Chemistry. 288: 32211-28. PMID 24045953 DOI: 10.1074/jbc.M113.510313  1
2013 Ringel AE, Wolberger C. A new RING tossed into an old HAT. Structure (London, England : 1993). 21: 1479-81. PMID 24010705 DOI: 10.1016/j.str.2013.08.011  1
2013 Wiener R, DiBello AT, Lombardi PM, Guzzo CM, Zhang X, Matunis MJ, Wolberger C. E2 ubiquitin-conjugating enzymes regulate the deubiquitinating activity of OTUB1. Nature Structural & Molecular Biology. 20: 1033-9. PMID 23955022 DOI: 10.1038/nsmb.2655  1
2013 Wiener R, Wolberger C. A new DUB makes linear ubiquitin a party to its own destruction. Cell. 153: 1189-91. PMID 23746836 DOI: 10.1016/j.cell.2013.05.018  1
2013 Fiedler KL, Bheda P, Dai J, Boeke JD, Wolberger C, Cotter RJ. A quantitative analysis of histone methylation and acetylation isoforms from their deuteroacetylated derivatives: application to a series of knockout mutants. Journal of Mass Spectrometry : Jms. 48: 608-15. PMID 23674285 DOI: 10.1002/jms.3198  1
2013 Bheda P, Wolberger C. Biochemistry: Sirtuin on a high-fat diet. Nature. 496: 41-2. PMID 23552941 DOI: 10.1038/496041a  1
2013 Berndsen CE, Wiener R, Yu IW, Ringel AE, Wolberger C. A conserved asparagine has a structural role in ubiquitin-conjugating enzymes. Nature Chemical Biology. 9: 154-6. PMID 23292652 DOI: 10.1038/nchembio.1159  1
2012 Guzzo CM, Berndsen CE, Zhu J, Gupta V, Datta A, Greenberg RA, Wolberger C, Matunis MJ. RNF4-dependent hybrid SUMO-ubiquitin chains are signals for RAP80 and thereby mediate the recruitment of BRCA1 to sites of DNA damage. Science Signaling. 5: ra88. PMID 23211528 DOI: 10.1126/scisignal.2003485  1
2012 Samara NL, Ringel AE, Wolberger C. A role for intersubunit interactions in maintaining SAGA deubiquitinating module structure and activity. Structure (London, England : 1993). 20: 1414-24. PMID 22771212 DOI: 10.1016/j.str.2012.05.015  1
2012 Bheda P, Swatkoski S, Fiedler KL, Boeke JD, Cotter RJ, Wolberger C. Biotinylation of lysine method identifies acetylated histone H3 lysine 79 in Saccharomyces cerevisiae as a substrate for Sir2. Proceedings of the National Academy of Sciences of the United States of America. 109: E916-25. PMID 22474337 DOI: 10.1073/pnas.1121471109  1
2012 Wiener R, Zhang X, Wang T, Wolberger C. The mechanism of OTUB1-mediated inhibition of ubiquitination. Nature. 483: 618-22. PMID 22367539 DOI: 10.1038/nature10911  1
2011 Cramer P, Wolberger C. Proteins: histones and chromatin. Current Opinion in Structural Biology. 21: 695-7. PMID 22079548 DOI: 10.1016/  1
2011 Samara NL, Wolberger C. A new chapter in the transcription SAGA. Current Opinion in Structural Biology. 21: 767-74. PMID 22014650 DOI: 10.1016/  1
2011 Berndsen CE, Wolberger C. A spectrophotometric assay for conjugation of ubiquitin and ubiquitin-like proteins. Analytical Biochemistry. 418: 102-10. PMID 21771579 DOI: 10.1016/j.ab.2011.06.034  1
2011 Bheda P, Wang JT, Escalante-Semerena JC, Wolberger C. Structure of Sir2Tm bound to a propionylated peptide. Protein Science : a Publication of the Protein Society. 20: 131-9. PMID 21080423 DOI: 10.1002/pro.544  1
2010 Samara NL, Datta AB, Berndsen CE, Zhang X, Yao T, Cohen RE, Wolberger C. Structural insights into the assembly and function of the SAGA deubiquitinating module. Science (New York, N.Y.). 328: 1025-9. PMID 20395473 DOI: 10.1126/science.1190049  1
2009 Fahie K, Hu P, Swatkoski S, Cotter RJ, Zhang Y, Wolberger C. Side chain specificity of ADP-ribosylation by a sirtuin. The Febs Journal. 276: 7159-76. PMID 19895577 DOI: 10.1111/j.1742-4658.2009.07427.x  1
2009 Hawse WF, Wolberger C. Structure-based mechanism of ADP-ribosylation by sirtuins. The Journal of Biological Chemistry. 284: 33654-61. PMID 19801667 DOI: 10.1074/jbc.M109.024521  1
2009 Datta AB, Hura GL, Wolberger C. The structure and conformation of Lys63-linked tetraubiquitin. Journal of Molecular Biology. 392: 1117-24. PMID 19664638 DOI: 10.1016/j.jmb.2009.07.090  1
2009 Fitzsimmons D, Lukin K, Lutz R, Garvie CW, Wolberger C, Hagman J. Highly cooperative recruitment of Ets-1 and release of autoinhibition by Pax5. Journal of Molecular Biology. 392: 452-64. PMID 19616560 DOI: 10.1016/j.jmb.2009.07.028  1
2009 Wang T, Yin L, Cooper EM, Lai MY, Dickey S, Pickart CM, Fushman D, Wilkinson KD, Cohen RE, Wolberger C. Evidence for bidentate substrate binding as the basis for the K48 linkage specificity of otubain 1. Journal of Molecular Biology. 386: 1011-23. PMID 19211026 DOI: 10.1016/j.jmb.2008.12.085  1
2008 Li Y, Zhang Y, Dorweiler B, Cui D, Wang T, Woo CW, Brunkan CS, Wolberger C, Imai S, Tabas I. Extracellular Nampt promotes macrophage survival via a nonenzymatic interleukin-6/STAT3 signaling mechanism. The Journal of Biological Chemistry. 283: 34833-43. PMID 18945671 DOI: 10.1074/jbc.M805866200  1
2008 Hawse WF, Hoff KG, Fatkins DG, Daines A, Zubkova OV, Schramm VL, Zheng W, Wolberger C. Structural insights into intermediate steps in the Sir2 deacetylation reaction. Structure (London, England : 1993). 16: 1368-77. PMID 18786399 DOI: 10.1016/j.str.2008.05.015  0.96
2008 Feeser EA, Wolberger C. Structural and functional studies of the Rap1 C-terminus reveal novel separation-of-function mutants. Journal of Molecular Biology. 380: 520-31. PMID 18538788 DOI: 10.1016/j.jmb.2008.04.078  1
2007 Wolberger C. Identification of a new nicotinamide binding site in a sirtuin: a reassessment. Molecular Cell. 28: 1102-3. PMID 18158906 DOI: 10.1016/j.molcel.2007.12.006  1
2007 Revollo JR, Körner A, Mills KF, Satoh A, Wang T, Garten A, Dasgupta B, Sasaki Y, Wolberger C, Townsend RR, Milbrandt J, Kiess W, Imai S. Nampt/PBEF/Visfatin regulates insulin secretion in beta cells as a systemic NAD biosynthetic enzyme. Cell Metabolism. 6: 363-75. PMID 17983582 DOI: 10.1016/j.cmet.2007.09.003  1
2007 Garrity J, Gardner JG, Hawse W, Wolberger C, Escalante-Semerena JC. N-lysine propionylation controls the activity of propionyl-CoA synthetase. The Journal of Biological Chemistry. 282: 30239-45. PMID 17684016 DOI: 10.1074/jbc.M704409200  1
2007 Huyton T, Wolberger C. The crystal structure of the tumor suppressor protein pp32 (Anp32a): structural insights into Anp32 family of proteins. Protein Science : a Publication of the Protein Society. 16: 1308-15. PMID 17567741 DOI: 10.1110/ps.072803507  1
2007 Eddins MJ, Varadan R, Fushman D, Pickart CM, Wolberger C. Crystal structure and solution NMR studies of Lys48-linked tetraubiquitin at neutral pH. Journal of Molecular Biology. 367: 204-11. PMID 17240395 DOI: 10.1016/j.jmb.2006.12.065  1
2006 Eddins MJ, Carlile CM, Gomez KM, Pickart CM, Wolberger C. Mms2-Ubc13 covalently bound to ubiquitin reveals the structural basis of linkage-specific polyubiquitin chain formation. Nature Structural & Molecular Biology. 13: 915-20. PMID 16980971 DOI: 10.1038/nsmb1148  1
2006 Haigis MC, Mostoslavsky R, Haigis KM, Fahie K, Christodoulou DC, Murphy AJ, Valenzuela DM, Yancopoulos GD, Karow M, Blander G, Wolberger C, Prolla TA, Weindruch R, Alt FW, Guarente L. SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells. Cell. 126: 941-54. PMID 16959573 DOI: 10.1016/j.cell.2006.06.057  1
2006 Hoff KG, Avalos JL, Sens K, Wolberger C. Insights into the sirtuin mechanism from ternary complexes containing NAD+ and acetylated peptide. Structure (London, England : 1993). 14: 1231-40. PMID 16905097 DOI: 10.1016/j.str.2006.06.006  0.68
2006 Wang T, Zhang X, Bheda P, Revollo JR, Imai S, Wolberger C. Structure of Nampt/PBEF/visfatin, a mammalian NAD+ biosynthetic enzyme. Nature Structural & Molecular Biology. 13: 661-2. PMID 16783373 DOI: 10.1038/nsmb1114  1
2006 Cosgrove MS, Bever K, Avalos JL, Muhammad S, Zhang X, Wolberger C. The structural basis of sirtuin substrate affinity. Biochemistry. 45: 7511-21. PMID 16768447 DOI: 10.1021/bi0526332  1
2006 Sauve AA, Wolberger C, Schramm VL, Boeke JD. The biochemistry of sirtuins. Annual Review of Biochemistry. 75: 435-65. PMID 16756498 DOI: 10.1146/annurev.biochem.74.082803.133500  1
2005 Cosgrove MS, Wolberger C. How does the histone code work? Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 83: 468-76. PMID 16094450 DOI: 10.1139/o05-137  1
2005 Hoff KG, Wolberger C. Getting a grip on O-acetyl-ADP-ribose. Nature Structural & Molecular Biology. 12: 560-1. PMID 15999106 DOI: 10.1038/nsmb0705-560  0.48
2005 Avalos JL, Bever KM, Wolberger C. Mechanism of sirtuin inhibition by nicotinamide: altering the NAD(+) cosubstrate specificity of a Sir2 enzyme. Molecular Cell. 17: 855-68. PMID 15780941 DOI: 10.1016/j.molcel.2005.02.022  1
2004 Cosgrove MS, Boeke JD, Wolberger C. Regulated nucleosome mobility and the histone code. Nature Structural & Molecular Biology. 11: 1037-43. PMID 15523479 DOI: 10.1038/nsmb851  1
2004 Schleif R, Wolberger C. Arm-domain interactions can provide high binding cooperativity. Protein Science : a Publication of the Protein Society. 13: 2829-31. PMID 15388867 DOI: 10.1110/ps.04908404  1
2004 Avalos JL, Boeke JD, Wolberger C. Structural basis for the mechanism and regulation of Sir2 enzymes. Molecular Cell. 13: 639-48. PMID 15023335 DOI: 10.1016/S1097-2765(04)00082-6  1
2003 Wu PY, Hanlon M, Eddins M, Tsui C, Rogers RS, Jensen JP, Matunis MJ, Weissman AM, Weisman AM, Weissman AM, Wolberger C, Wolberger CP, Pickart CM. A conserved catalytic residue in the ubiquitin-conjugating enzyme family. The Embo Journal. 22: 5241-50. PMID 14517261 DOI: 10.1038/sj.emboj.7601829  1
2003 LaRonde-LeBlanc NA, Wolberger C. Structure of HoxA9 and Pbx1 bound to DNA: Hox hexapeptide and DNA recognition anterior to posterior. Genes & Development. 17: 2060-72. PMID 12923056 DOI: 10.1101/gad.1103303  1
2003 Aishima J, Wolberger C. Insights into nonspecific binding of homeodomains from a structure of MATalpha2 bound to DNA. Proteins. 51: 544-51. PMID 12784213 DOI: 10.1002/prot.10375  1
2003 Ke A, Wolberger C. Insights into binding cooperativity of MATa1/MATalpha2 from the crystal structure of a MATa1 homeodomain-maltose binding protein chimera. Protein Science : a Publication of the Protein Society. 12: 306-12. PMID 12538894 DOI: 10.1110/ps.0219103  1
2002 Aishima J, Gitti RK, Noah JE, Gan HH, Schlick T, Wolberger C. A Hoogsteen base pair embedded in undistorted B-DNA. Nucleic Acids Research. 30: 5244-52. PMID 12466549 DOI: 10.1093/nar/gkf661  1
2002 Avalos JL, Celic I, Muhammad S, Cosgrove MS, Boeke JD, Wolberger C. Structure of a Sir2 enzyme bound to an acetylated p53 peptide. Molecular Cell. 10: 523-35. PMID 12408821 DOI: 10.1016/S1097-2765(02)00628-7  1
2002 Park JH, Cosgrove MS, Youngman E, Wolberger C, Boeke JD. A core nucleosome surface crucial for transcriptional silencing. Nature Genetics. 32: 273-9. PMID 12244315 DOI: 10.1038/ng982  1
2002 Garvie CW, Pufall MA, Graves BJ, Wolberger C. Structural analysis of the autoinhibition of Ets-1 and its role in protein partnerships. The Journal of Biological Chemistry. 277: 45529-36. PMID 12221090 DOI: 10.1074/jbc.M206327200  1
2002 Ke A, Mathias JR, Vershon AK, Wolberger C. Structural and thermodynamic characterization of the DNA binding properties of a triple alanine mutant of MATalpha2. Structure (London, England : 1993). 10: 961-71. PMID 12121651 DOI: 10.1016/S0969-2126(02)00790-6  1
2002 Smith JS, Avalos J, Celic I, Muhammad S, Wolberger C, Boeke JD. SIR2 family of NAD(+)-dependent protein deacetylases. Methods in Enzymology. 353: 282-300. PMID 12078503 DOI: 10.1016/S0076-6879(02)53056-1  1
2002 Müller CW, Wolberger C. Protein-nucleic acid interactions Current Opinion in Structural Biology. 12: 69-71. DOI: 10.1016/S0959-440X(02)00291-9  1
2001 Garvie CW, Hagman J, Wolberger C. Structural studies of Ets-1/Pax5 complex formation on DNA. Molecular Cell. 8: 1267-76. PMID 11779502 DOI: 10.1016/S1097-2765(01)00410-5  1
2001 Garvie CW, Wolberger C. Recognition of specific DNA sequences. Molecular Cell. 8: 937-46. PMID 11741530 DOI: 10.1016/S1097-2765(01)00392-6  1
2001 Olson WK, Bansal M, Burley SK, Dickerson RE, Gerstein M, Harvey SC, Heinemann U, Lu XJ, Neidle S, Shakked Z, Sklenar H, Suzuki M, Tung CS, Westhof E, Wolberger C, et al. A standard reference frame for the description of nucleic acid base-pair geometry. Journal of Molecular Biology. 313: 229-37. PMID 11601858 DOI: 10.1006/jmbi.2001.4987  1
2001 VanDemark AP, Hofmann RM, Tsui C, Pickart CM, Wolberger C. Molecular insights into polyubiquitin chain assembly: crystal structure of the Mms2/Ubc13 heterodimer. Cell. 105: 711-20. PMID 11440714 DOI: 10.1016/S0092-8674(01)00387-7  1
2000 LaRonde-LeBlanc N, Wolberger C. Characterization of the oligomeric states of wild type and mutant AraC. Biochemistry. 39: 11593-601. PMID 10995226 DOI: 10.1021/bi001262g  1
2000 Sprague ER, Redd MJ, Johnson AD, Wolberger C. Structure of the C-terminal domain of Tup1, a corepressor of transcription in yeast. The Embo Journal. 19: 3016-27. PMID 10856245 DOI: 10.1093/emboj/19.12.3016  1
2000 Smith JS, Brachmann CB, Celic I, Kenna MA, Muhammad S, Starai VJ, Avalos JL, Escalante-Semerena JC, Grubmeyer C, Wolberger C, Boeke JD. A phylogenetically conserved NAD+-dependent protein deacetylase activity in the Sir2 protein family. Proceedings of the National Academy of Sciences of the United States of America. 97: 6658-63. PMID 10841563 DOI: 10.1073/pnas.97.12.6658  1
2000 Wolberger C, Campbell R. New perch for the winged helix. Nature Structural Biology. 7: 261-2. PMID 10742162 DOI: 10.1038/74004  1
2000 Jabet C, Sprague ER, VanDemark AP, Wolberger C. Characterization of the N-terminal domain of the yeast transcriptional repressor Tup1. Proposal for an association model of the repressor complex Tup1 x Ssn6. The Journal of Biological Chemistry. 275: 9011-8. PMID 10722750 DOI: 10.1074/jbc.275.12.9011  1
1999 Jabet C, Gitti R, Summers MF, Wolberger C. NMR studies of the pbx1 TALE homeodomain protein free in solution and bound to DNA: proposal for a mechanism of HoxB1-Pbx1-DNA complex assembly. Journal of Molecular Biology. 291: 521-30. PMID 10448033 DOI: 10.1006/jmbi.1999.2983  1
1999 Wolberger C. Multiprotein-DNA complexes in transcriptional regulation. Annual Review of Biophysics and Biomolecular Structure. 28: 29-56. PMID 10410794 DOI: 10.1146/annurev.biophys.28.1.29  1
1999 Piper DE, Batchelor AH, Chang CP, Cleary ML, Wolberger C. Structure of a HoxB1-Pbx1 heterodimer bound to DNA: role of the hexapeptide and a fourth homeodomain helix in complex formation. Cell. 96: 587-97. PMID 10052460 DOI: 10.1016/S0092-8674(00)80662-5  1
1998 Li T, Jin Y, Vershon AK, Wolberger C. Crystal structure of the MATa1/MATalpha2 homeodomain heterodimer in complex with DNA containing an A-tract. Nucleic Acids Research. 26: 5707-18. PMID 9838003  1
1998 Wolberger C. Combinatorial transcription factors. Current Opinion in Genetics & Development. 8: 552-9. PMID 9794820 DOI: 10.1016/S0959-437X(98)80010-5  1
1998 Batchelor AH, Piper DE, de la Brousse FC, McKnight SL, Wolberger C. The structure of GABPalpha/beta: an ETS domain- ankyrin repeat heterodimer bound to DNA. Science (New York, N.Y.). 279: 1037-41. PMID 9461436 DOI: 10.1126/science.279.5353.1037  1
1997 Soisson SM, MacDougall-Shackleton B, Schleif R, Wolberger C. The 1.6 A crystal structure of the AraC sugar-binding and dimerization domain complexed with D-fucose. Journal of Molecular Biology. 273: 226-37. PMID 9367758 DOI: 10.1006/jmbi.1997.1314  1
1997 Soisson SM, MacDougall-Shackleton B, Schleif R, Wolberger C. Structural basis for ligand-regulated oligomerization of AraC. Science (New York, N.Y.). 276: 421-5. PMID 9103202 DOI: 10.1126/science.276.5311.421  1
1996 Wolberger C. Homeodomain interactions. Current Opinion in Structural Biology. 6: 62-8. PMID 8696974 DOI: 10.1016/S0959-440X(96)80096-0  1
1996 Wolberger C, Li T. Structure of the yeast a1/α2 homeodomain heterodimer bound to dna Faseb Journal. 10: A1136.  1
1995 Li T, Stark M, Johnson AD, Wolberger C. Crystallization and preliminary X-ray diffraction studies of an a1/alpha 2/DNA ternary complex. Proteins. 21: 161-4. PMID 7777491 DOI: 10.1002/prot.340210210  1
1995 Jin Y, Mead J, Li T, Wolberger C, Vershon AK. Altered DNA recognition and bending by insertions in the alpha 2 tail of the yeast a1/alpha 2 homeodomain heterodimer. Science (New York, N.Y.). 270: 290-3. PMID 7569977 DOI: 10.1126/science.270.5234.290  1
1995 Li T, Stark MR, Johnson AD, Wolberger C. Crystal structure of the MATa1/MAT alpha 2 homeodomain heterodimer bound to DNA. Science (New York, N.Y.). 270: 262-9. PMID 7569974 DOI: 10.1126/science.270.5234.262  1
1994 Wolberger C. b/HLH without the zip. Nature Structural Biology. 1: 413-6. PMID 7664056  1
1993 Wolberger C. Structure and DNA binding of the yeast MAT alpha 2 homeodomain. Cold Spring Harbor Symposia On Quantitative Biology. 58: 159-66. PMID 7956026 DOI: 10.1101/SQB.1993.058.01.020  1
1993 Wolberger C. Transcription factor structure and DNA binding Current Opinion in Structural Biology. 3: 3-10. DOI: 10.1016/0959-440X(93)90194-P  1
1991 Wolberger C, Pabo CO, Vershon AK, Johnson AD. Crystallization and preliminary X-ray diffraction studies of a MAT alpha 2-DNA complex. Journal of Molecular Biology. 217: 11-3. PMID 1988673 DOI: 10.1016/0022-2836(91)90605-6  1
1991 Wolberger C, Vershon AK, Liu B, Johnson AD, Pabo CO. Crystal structure of a MAT alpha 2 homeodomain-operator complex suggests a general model for homeodomain-DNA interactions. Cell. 67: 517-28. PMID 1682054 DOI: 10.1016/0092-8674(91)90526-5  1
1989 Mondragón A, Wolberger C, Harrison SC. Structure of phage 434 Cro protein at 2.35 A resolution. Journal of Molecular Biology. 205: 179-88. PMID 2647998 DOI: 10.1016/0022-2836(89)90374-4  1
1988 Harrison SC, Anderson JE, Koudelka GB, Mondragon A, Subbiah S, Wharton RP, Wolberger C, Ptashne M. Recognition of DNA sequences by the repressor of bacteriophage 434. Biophysical Chemistry. 29: 31-7. PMID 3359001 DOI: 10.1016/0301-4622(88)87022-4  1
1988 Wolberger C, Dong YC, Ptashne M, Harrison SC. Structure of a phage 434 Cro/DNA complex. Nature. 335: 789-95. PMID 3185709 DOI: 10.1038/335789a0  1
1988 Harrison SC, Ptashne M, Anderson JE, Dong YC, Drottar M, Koudelka GB, Mondragon A, Subbiah S, Wharton RP, Wolberger C. Recognition of DNA sequences by the repressor and Cro proteins of bacteriophage 434 Bulletin De L'Institut Pasteur. 86: 55-64.  1
1987 Wolberger C, Harrison SC. Crystallization and X-ray diffraction studies of a 434 Cro-DNA complex. Journal of Molecular Biology. 196: 951-4. PMID 3681985 DOI: 10.1016/0022-2836(87)90419-0  1
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