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Paul H. Weigel - Related publications

Affiliations: 
Biochemistry and Molecular Biology University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States 
Area:
Structure-function of Glycosaminoglycan Receptors and Hyaluronic Acid Synthases and their roles in human diseases
Website:
http://www.oumedicine.com/department-of-biochemistry-and-molecular-biology/faculty/paul-h-weigel-ph-d-
NOTE: We are testing a new system for identifying relevant work based on semantic analysis that identifies similarities between recently published papers and the current author's publications. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches.
50 most relevant papers in past 60 days:
Year Citation  Score
2020 Yeliseev A, van den Berg A, Zoubak L, Hines K, Stepnowski S, Williston K, Yan W, Gawrisch K, Zmuda J. Thermostability of a recombinant G protein-coupled receptor expressed at high level in mammalian cell culture. Scientific Reports. 10: 16805. PMID 33033368 DOI: 10.1038/s41598-020-73813-7   
2020 Reeh K, Summers PA, Gould IR, Woscholski R, Vilar R. Design, synthesis and evaluation of a tripodal receptor for phosphatidylinositol phosphates. Scientific Reports. 10: 18450. PMID 33116198 DOI: 10.1038/s41598-020-75484-w   
2020 Pereira PMR, Mandleywala K, Ragupathi A, Lewis JS. Acute statin treatment improves antibody accumulation in EGFR- and PSMA-expressing tumors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 32998959 DOI: 10.1158/1078-0432.CCR-20-1960   
2020 Fernandes RA, Su L, Nishiga Y, Ren J, Bhuiyan AM, Cheng N, Kuo CJ, Picton LK, Ohtsuki S, Majzner RG, Rietberg SP, Mackall CL, Yin Q, Ali LR, Yang X, et al. Immune receptor inhibition through enforced phosphatase recruitment. Nature. PMID 33087934 DOI: 10.1038/s41586-020-2851-2   
2020 Yang LK, Tao YX. Alanine Scanning Mutagenesis of the DRYxxI Motif and Intracellular Loop 2 of Human Melanocortin-4 Receptor. International Journal of Molecular Sciences. 21. PMID 33076233 DOI: 10.3390/ijms21207611   
2020 Grosicki M, Adami M, Micheloni C, Głuch-Lutwin M, Siwek A, Latacz G, Łażewska D, Więcek M, Reiner D, Stark H, Chlopicki S, Kieć-Kononowicz K. Eosinophils adhesion assay as a tool for phenotypic drug screening - The pharmacology of 1,3,5 - Triazine and 1h-indole like derivatives against the human histamine H receptor. European Journal of Pharmacology. 173611. PMID 33017589 DOI: 10.1016/j.ejphar.2020.173611   
2020 Navarro G, Gonzalez A, Campanacci S, Rivas-Santisteban R, Reyes-Resina I, Casajuana-Martin N, Cordomí A, Pardo L, Franco R. Experimental and computational analysis of biased agonism on full-length and a C-terminally truncated adenosine A receptor. Computational and Structural Biotechnology Journal. 18: 2723-2732. PMID 33101610 DOI: 10.1016/j.csbj.2020.09.028   
2020 Watabe M, Yoshimura H, Arjunan SNV, Kaizu K, Takahashi K. Signaling activations through G-protein-coupled-receptor aggregations. Physical Review. E. 102: 032413. PMID 33076007 DOI: 10.1103/PhysRevE.102.032413   
2020 Kukkonen JP. Allosteric interactions via the orthosteric ligand binding sites in a constitutive G-protein-coupled receptor homodimer. Pharmacological Research. 105116. PMID 32783977 DOI: 10.1016/j.phrs.2020.105116   
2020 da Rocha-Azevedo B, Lee S, Dasgupta A, Vega AR, de Oliveira LR, Kim T, Kittisopikul M, Malik ZA, Jaqaman K. Heterogeneity in VEGF Receptor-2 Mobility and Organization on the Endothelial Cell Surface Leads to Diverse Models of Activation by VEGF. Cell Reports. 32: 108187. PMID 32997988 DOI: 10.1016/j.celrep.2020.108187   
2020 Işbilir A, Möller J, Arimont M, Bobkov V, Perpiñá-Viciano C, Hoffmann C, Inoue A, Heukers R, de Graaf C, Smit MJ, Annibale P, Lohse MJ. Advanced fluorescence microscopy reveals disruption of dynamic CXCR4 dimerization by subpocket-specific inverse agonists. Proceedings of the National Academy of Sciences of the United States of America. PMID 33148803 DOI: 10.1073/pnas.2013319117   
2020 Kopp N, Holtschulte C, Börgel F, Lehmkuhl K, Friedland K, Civenni G, Laurini E, Catapano CV, Pricl S, Humpf HU, Schepmann D, Wünsch B. Novel σ antagonists designed for tumor therapy: Structure - activity relationships of aminoethyl substituted cyclohexanes. European Journal of Medicinal Chemistry. 112950. PMID 33148494 DOI: 10.1016/j.ejmech.2020.112950   
2020 Harms M, Gilg A, Ständker L, Beer AJ, Mayer B, Rasche V, Gruber CW, Münch J. Microtiter plate-based antibody-competition assay to determine binding affinities and plasma/blood stability of CXCR4 ligands. Scientific Reports. 10: 16036. PMID 32994431 DOI: 10.1038/s41598-020-73012-4   
2020 Liu X, Wu Y, Zhou D, Xie Y, Zhou Y, Lu Y, Yang R, Liu S. N‑linoleyltyrosine protects PC12 cells against oxidative damage via autophagy: Possible involvement of CB1 receptor regulation. International Journal of Molecular Medicine. 46: 1827-1837. PMID 33000188 DOI: 10.3892/ijmm.2020.4706   
2020 Symeonidis D, Lazaris A, Zizi Zerbetzoglou A, Christodoulou P, Kavantzas N, Tsavaris N, Thomopoulou GE. Correlation between LGR5 stem cells and location of tumor as well as age, sex and metastasis in colon adenocarcinoma. Journal of B.U.On. : Official Journal of the Balkan Union of Oncology. 25: 1827-1831. PMID 33099920   
2020 Norel X, Sugimoto Y, Ozen G, Abdelazeem H, Amgoud Y, Bouhadoun A, Bassiouni W, Goepp M, Mani S, Manikpurage HD, Senbel A, Longrois D, Heinemann A, Yao C, Clapp LH. International Union of Basic and Clinical Pharmacology. CIX. Differences and Similarities between Human and Rodent Prostaglandin E Receptors (EP1-4) and Prostacyclin Receptor (IP): Specific Roles in Pathophysiologic Conditions. Pharmacological Reviews. 72: 910-968. PMID 32962984 DOI: 10.1124/pr.120.019331   
2020 Bertevello CR, Russo BRA, Tahira AC, Lopes-Junior EH, DeMarco R, Oliveira KC. The evolution of TNF signaling in platyhelminths suggests the cooptation of TNF receptor in the host-parasite interplay. Parasites & Vectors. 13: 491. PMID 32977830 DOI: 10.1186/s13071-020-04370-1   
2020 Yuan C, Ni L, Zhang C, Wu X. The Role of Notch3 Signaling in Kidney Disease. Oxidative Medicine and Cellular Longevity. 2020: 1809408. PMID 33149805 DOI: 10.1155/2020/1809408   
2020 Wu Z, Newstead S, Biggin PC. The KDEL trafficking receptor exploits pH to tune the strength of an unusual short hydrogen bond. Scientific Reports. 10: 16903. PMID 33037300 DOI: 10.1038/s41598-020-73906-3   
2020 Lyons EL, Leone-Kabler S, Kovach AL, Thomas BF, Howlett AC. Cannabinoid receptor subtype influence on neuritogenesis in human SH-SY5Y cells. Molecular and Cellular Neurosciences. 103566. PMID 33049367 DOI: 10.1016/j.mcn.2020.103566   
2020 Holze J, Bermudez M, Pfeil EM, Kauk M, Bödefeld T, Irmen M, Matera C, Dallanoce C, De Amici M, Holzgrabe U, König GM, Tränkle C, Wolber G, Schrage R, Mohr K, et al. Ligand-Specific Allosteric Coupling Controls G-Protein-Coupled Receptor Signaling. Acs Pharmacology & Translational Science. 3: 859-867. PMID 33073186 DOI: 10.1021/acsptsci.0c00069   
2020 Igawa T, Kishikawa S, Abe Y, Tsuda M, Inoue K, Ueda T. Analysis of binding residues in monoclonal antibody with high affinity for the head domain of the rat P2X4 receptor. Journal of Biochemistry. PMID 33169129 DOI: 10.1093/jb/mvaa124   
2020 Karra AG, Tziortziou M, Kylindri P, Georgatza D, Gorgogietas VA, Makiou A, Krokida A, Tsialtas I, Kalousi FD, Papadopoulos GE, Papadopoulou KΚ, Psarra AG. Boswellic acids and their derivatives as potent regulators of glucocorticoid receptor actions. Archives of Biochemistry and Biophysics. 695: 108656. PMID 33127380 DOI: 10.1016/j.abb.2020.108656   
2020 Yang JF, Williams AH, Penthala NR, Prather PL, Crooks PA, Zhan CG. Binding Modes and Selectivity of Cannabinoid 1 (CB1) and Cannabinoid 2 (CB2) Receptor Ligands. Acs Chemical Neuroscience. PMID 32997485 DOI: 10.1021/acschemneuro.0c00551   
2020 Pandey S, Saha S, Shukla AK. Transmitting the Signal: Structure of the β1-Adrenergic Receptor-Gs Protein Complex. Molecular Cell. 80: 3-5. PMID 33007256 DOI: 10.1016/j.molcel.2020.09.016   
2020 Pandey S, Saha S, Shukla AK. Transmitting the Signal: Structure of the β1-Adrenergic Receptor-Gs Protein Complex. Molecular Cell. 80: 3-5. PMID 33007256 DOI: 10.1016/j.molcel.2020.09.016   
2020 Moya B, Tontini C, Santos A. IgE sialylation: unravelling a key anaphylactic mediator. Allergy. PMID 33147354 DOI: 10.1111/all.14649   
2020 Peri SSS, Sabnani MK, Raza MU, Urquhart EL, Ghaffari S, Lee J, Kim M, Weidanz JA, Alexandrakis G. Quantification of Low Affinity Binding Interactions between Natural Killer Cell Inhibitory Receptors and Targeting Ligands with a Self-Induced Back-Action Actuated Nanopore Electrophoresis (SANE) Sensor. Nanotechnology. PMID 33027774 DOI: 10.1088/1361-6528/abbf26   
2020 Velard F, Chatron-Colliet A, Côme D, Ah-Kioon MD, Lin H, Hafsia N, Cohen-Solal M, Ea HK, Lioté F. Adrenomedullin and truncated peptide adrenomedullin(22-52) affect chondrocyte response to apoptotis in vitro: downregulation of FAS protects chondrocyte from cell death. Scientific Reports. 10: 16740. PMID 33028903 DOI: 10.1038/s41598-020-73924-1   
2020 Ramesh S, Park S, Call MJ, Im W, Call ME. Experimentally Guided Computational Methods Yield Highly Accurate Insights into Transmembrane Interactions within the T Cell Receptor Complex. The Journal of Physical Chemistry. B. PMID 33030343 DOI: 10.1021/acs.jpcb.0c06403   
2020 Tapia C, Zamarreño F, Salvador GA, Casali CI, Viso J, Fernandez MDC, White JH, González-Pardo V. Down-regulation of COX-2 activity by 1α,25(OH)D is VDR dependent in endothelial cells transformed by Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor. Heliyon. 6: e05149. PMID 33072916 DOI: 10.1016/j.heliyon.2020.e05149   
2020 Kurtz R, Steinberg LG, Betcher M, Fowler D, Shepard BD. The Sensing Liver: Localization and Ligands for Hepatic Murine Olfactory and Taste Receptors. Frontiers in Physiology. 11: 574082. PMID 33123030 DOI: 10.3389/fphys.2020.574082   
2020 Jakubík J, Randáková A, Chetverikov N, El-Fakahany EE, Doležal V. The operational model of allosteric modulation of pharmacological agonism. Scientific Reports. 10: 14421. PMID 32879329 DOI: 10.1038/s41598-020-71228-y   
2020 Touma AM, Malik RU, Gupte T, Sivaramakrishnan S. Allosteric modulation of adenosine A1 and cannabinoid 1 receptor signaling by G-peptides. Pharmacology Research & Perspectives. 8: e00673. PMID 33124765 DOI: 10.1002/prp2.673   
2020 Lucianò AM, Tata AM. Functional Characterization of Cholinergic Receptors in Melanoma Cells. Cancers. 12. PMID 33120929 DOI: 10.3390/cancers12113141   
2020 Ricart-Ortega M, Berizzi AE, Pereira V, Malhaire F, Catena J, Font J, Gómez-Santacana X, Muñoz L, Zussy C, Serra C, Rovira X, Goudet C, Llebaria A. Mechanistic Insights into Light-Driven Allosteric Control of GPCR Biological Activity. Acs Pharmacology & Translational Science. 3: 883-895. PMID 33073188 DOI: 10.1021/acsptsci.0c00054   
2020 Gasperotti AF, Karina Herrera Seitz M, Balmaceda RS, Prosa LM, Jung K, Studdert CA. Direct binding of benzoate derivatives to two chemoreceptors with Cache sensor domains in Halomonas titanicae KHS3. Molecular Microbiology. PMID 33098326 DOI: 10.1111/mmi.14630   
2020 Goldeman C, Andersen M, Al-Robai A, Buchholtz T, Svane N, Ozgür B, Holst B, Shusta E, Hall V, Saaby L, Hyttel P, Brodin B. Human induced pluripotent stem cells (BIONi010-C) generate tight cell monolayers with blood-brain barrier traits and functional expression of large neutral amino acid transporter 1 (SLC7A5). European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 105577. PMID 33011235 DOI: 10.1016/j.ejps.2020.105577   
2020 Pressly B, Lee RD, Barnych B, Hammock BD, Wulff H. Identification of the Functional Binding Site for the Convulsant Tetramethylenedisulfotetramine in the Pore of the α2β3γ2 GABA-A Receptor. Molecular Pharmacology. PMID 33109687 DOI: 10.1124/molpharm.120.000090   
2020 Xie XY, Li YY, Ma WH, Chen AF, Sun YT, Lee JY, Riad A, Xu DH, Mach RH, Huang YS. Synthesis, binding, and functional properties of tetrahydroisoquinolino-2-alkyl phenones as selective σR/TMEM97 ligands. European Journal of Medicinal Chemistry. 209: 112906. PMID 33049607 DOI: 10.1016/j.ejmech.2020.112906   
2020 Bourdet DL, Yeola S, Hegde SS, Colson PJ, Barnes CN, Borin MT. . Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 32978223 DOI: 10.1124/dmd.120.000103   
2020 Jones EM, Lubock NB, Venkatakrishnan AJ, Wang J, Tseng AM, Paggi JM, Latorraca NR, Cancilla D, Satyadi M, Davis JE, Babu MM, Dror RO, Kosuri S. Structural and functional characterization of G protein-coupled receptors with deep mutational scanning. Elife. 9. PMID 33084570 DOI: 10.7554/eLife.54895   
2020 Kotouza MT, Gemenetzi K, Galigalidou C, Vlachonikola E, Pechlivanis N, Agathangelidis A, Sandaltzopoulos R, Mitkas PA, Stamatopoulos K, Chatzidimitriou A, Psomopoulos FE, . TRIP - T cell receptor/immunoglobulin profiler. Bmc Bioinformatics. 21: 422. PMID 32993478 DOI: 10.1186/s12859-020-03669-1   
2020 Cao J, Li C, Ma P, Ding Y, Gao J, Jia Q, Zhu J, Zhang T. Effect of kaempferol on IgE-mediated anaphylaxis in C57BL/6 mice and LAD2 cells. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 79: 153346. PMID 33002828 DOI: 10.1016/j.phymed.2020.153346   
2020 Bernhard M, Laube B. Thermophoretic analysis of ligand-specific conformational states of the inhibitory glycine receptor embedded in copolymer nanodiscs. Scientific Reports. 10: 16569. PMID 33024136 DOI: 10.1038/s41598-020-73157-2   
2020 Jin Y, Qiu CY, Wei S, Han L, Liu TT, Hu WP. Potentiation of P2X3 receptor mediated currents by endothelin-1 in rat dorsal root ganglion neurons. Neuropharmacology. 108356. PMID 33069757 DOI: 10.1016/j.neuropharm.2020.108356   
2020 Pieterse L, van der Walt MM, Terre'Blanche G. C2-substituted quinazolinone derivatives exhibit A and/or A adenosine receptor affinities in the low micromolar range. Bioorganic & Medicinal Chemistry Letters. 30: 127274. PMID 32631506 DOI: 10.1016/j.bmcl.2020.127274   
2020 Leung SW. The vascular impact of IP-TP receptor interactions. Acta Physiologica (Oxford, England). e13577. PMID 33135294 DOI: 10.1111/apha.13577   
2020 Shehroz M, Zaheer T, Hussain T. Computer-aided drug design against spike glycoprotein of SARS-CoV-2 to aid COVID-19 treatment. Heliyon. 6: e05278. PMID 33083627 DOI: 10.1016/j.heliyon.2020.e05278   
2020 Esteoulle L, Daubeuf F, Collot M, Riché S, Durroux T, Brasse D, Marchand P, Karpenko IA, Klymchenko AS, Bonnet D. A near-infrared fluorogenic dimer enables background-free imaging of endogenous GPCRs in living mice. Chemical Science. 11: 6824-6829. PMID 33033597 DOI: 10.1039/d0sc01018a