Dalibor Sames - Publications

Affiliations: 
Chemistry Columbia University, New York, NY 
Area:
organic synthesis
Website:
http://www.columbia.edu/cu/chemistry/groups/sames/dali.html

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Year Citation  Score
2022 Cunningham MJ, Bock HA, Serrano IC, Bechand B, Vidyadhara DJ, Bonniwell EM, Lankri D, Duggan P, Nazarova AL, Cao AB, Calkins MM, Khirsariya P, Hwu C, Katritch V, Chandra SS, ... ... Sames D, et al. Pharmacological Mechanism of the Non-hallucinogenic 5-HT Agonist Ariadne and Analogs. Acs Chemical Neuroscience. PMID 36521179 DOI: 10.1021/acschemneuro.2c00597  0.761
2022 Pazos M, Dibello E, Mesa JM, Sames D, Comini MA, Seoane G, Carrera I. Iboga Inspired -Indolylethyl-Substituted Isoquinuclidines as a Bioactive Scaffold: Chemoenzymatic Synthesis and Characterization as GDNF Releasers and Antitrypanosoma Agents. Molecules (Basel, Switzerland). 27. PMID 35164094 DOI: 10.3390/molecules27030829  0.783
2021 Bhowmik S, Galeta J, Havel V, Nelson M, Faouzi A, Bechand B, Ansonoff M, Fiala T, Hunkele A, Kruegel AC, Pintar JE, Majumdar S, Javitch JA, Sames D. Site selective C-H functionalization of Mitragyna alkaloids reveals a molecular switch for tuning opioid receptor signaling efficacy. Nature Communications. 12: 3858. PMID 34158473 DOI: 10.1038/s41467-021-23736-2  0.766
2020 Rodríguez P, Urbanavicius J, Prieto JP, Fabius S, Reyes AL, Havel V, Sames D, Scorza C, Carrera I. A Single Administration of the Atypical Psychedelic Ibogaine or its Metabolite Noribogaine Induces an Antidepressant-like Effect in Rats. Acs Chemical Neuroscience. PMID 32330007 DOI: 10.1021/Acschemneuro.0C00152  0.671
2019 Marton S, González B, Rodríguez-Bottero S, Miquel E, Martínez-Palma L, Pazos M, Prieto JP, Rodríguez P, Sames D, Seoane G, Scorza C, Cassina P, Carrera I. Ibogaine Administration Modifies GDNF and BDNF Expression in Brain Regions Involved in Mesocorticolimbic and Nigral Dopaminergic Circuits. Frontiers in Pharmacology. 10: 193. PMID 30890941 DOI: 10.3389/Fphar.2019.00193  0.762
2017 Henke A, Kovalyova Y, Dunn M, Dreier D, Gubernator NG, Dincheva I, Hwu C, Sebej P, Ansorge MS, Sulzer D, Sames D. Toward Serotonin Fluorescent False Neurotransmitters: Development of Fluorescent Dual Serotonin and Vesicular Monoamine Transporter Substrates for Visualizing Serotonin Neurons. Acs Chemical Neuroscience. PMID 29281252 DOI: 10.1021/Acschemneuro.7B00320  0.309
2017 Boltaev U, Meyer Y, Tolibzoda F, Jacques T, Gassaway M, Xu Q, Wagner F, Zhang YL, Palmer M, Holson E, Sames D. Multiplex quantitative assays indicate a need for reevaluating reported small-molecule TrkB agonists. Science Signaling. 10. PMID 28831019 DOI: 10.1126/Scisignal.Aal1670  0.768
2016 Genovino J, Sames D, Hamann LG, Touré BB. Accessing Drug Metabolites via Transition-Metal Catalyzed C-H Oxidation: Liver as Synthetic Inspiration. Angewandte Chemie (International Ed. in English). PMID 27723189 DOI: 10.1002/Anie.201602644  0.308
2016 Pereira DB, Schmitz Y, Mészáros J, Merchant P, Hu G, Li S, Henke A, Lizardi-Ortiz JE, Karpowicz RJ, Morgenstern TJ, Sonders MS, Kanter E, Rodriguez PC, Mosharov EV, Sames D, et al. Fluorescent false neurotransmitter reveals functionally silent dopamine vesicle clusters in the striatum. Nature Neuroscience. PMID 26900925 DOI: 10.1038/Nn.4252  0.635
2016 Genovino J, Sames D, Hamann LG, Touré BB. Die Erschließung von Wirkstoffmetaboliten durch übergangsmetallkatalysierte C-H-Oxidation: die Leber als Inspiration für die Synthese Angewandte Chemie. 128: 14430-14451. DOI: 10.1002/Ange.201602644  0.318
2015 Gassaway MM, Jacques TL, Kruegel AC, Karpowicz RJ, Li X, Li S, Myer Y, Sames D. Deconstructing the Iboga Alkaloid Skeleton: Potentiation of FGF2-induced Glial Cell Line-Derived Neurotrophic Factor Release by a Novel Compound. Acs Chemical Biology. PMID 26517751 DOI: 10.1021/Acschembio.5B00678  0.771
2015 Kruegel AC, Rakshit S, Li X, Sames D. Constructing Iboga alkaloids via C-H bond functionalization: examination of the direct and catalytic union of heteroarenes and isoquinuclidine alkenes. The Journal of Organic Chemistry. 80: 2062-71. PMID 25633249 DOI: 10.1021/Jo5018102  0.409
2014 Genovino J, Sames D, Touré BB. Access to drug metabolites via C-H functionalization: Copper-catalyzed aerobic oxidation of N,N-dimethylalkylamines in complex pharmaceuticals Tetrahedron Letters. DOI: 10.1016/J.Tetlet.2014.11.037  0.309
2013 Genovino J, Lütz S, Sames D, Touré BB. Complementation of biotransformations with chemical C-H oxidation: copper-catalyzed oxidation of tertiary amines in complex pharmaceuticals. Journal of the American Chemical Society. 135: 12346-52. PMID 23875728 DOI: 10.1021/Ja405471H  0.342
2013 Hu G, Henke A, Karpowicz RJ, Sonders MS, Farrimond F, Edwards R, Sulzer D, Sames D. New fluorescent substrate enables quantitative and high-throughput examination of vesicular monoamine transporter 2 (VMAT2). Acs Chemical Biology. 8: 1947-54. PMID 23859623 DOI: 10.1021/Cb400259N  0.351
2013 Karpowicz RJ, Dunn M, Sulzer D, Sames D. APP+, a fluorescent analogue of the neurotoxin MPP+, is a marker of catecholamine neurons in brain tissue, but not a fluorescent false neurotransmitter. Acs Chemical Neuroscience. 4: 858-69. PMID 23647019 DOI: 10.1021/Cn400038U  0.311
2013 Rodriguez PC, Pereira DB, Borgkvist A, Wong MY, Barnard C, Sonders MS, Zhang H, Sames D, Sulzer D. Fluorescent dopamine tracer resolves individual dopaminergic synapses and their activity in the brain. Proceedings of the National Academy of Sciences of the United States of America. 110: 870-5. PMID 23277566 DOI: 10.1073/Pnas.1213569110  0.647
2013 Joo JM, Guo P, Sames D. C-H bonds as ubiquitous functionality: preparation of multiple regioisomers of arylated 1,2,4-triazoles via C-H arylation. The Journal of Organic Chemistry. 78: 738-43. PMID 23276283 DOI: 10.1021/Jo3021677  0.415
2012 Vadola PA, Sames D. Catalytic coupling of arene C-H bonds and alkynes for the synthesis of coumarins: substrate scope and application to the development of neuroimaging agents. The Journal of Organic Chemistry. 77: 7804-14. PMID 22768913 DOI: 10.1021/Jo3006842  0.807
2012 Vadola PA, Carrera I, Sames D. C-H bond functionalization via hydride transfer: formation of α-arylated piperidines and 1,2,3,4-tetrahydroisoquinolines via stereoselective intramolecular amination of benzylic C-H bonds. The Journal of Organic Chemistry. 77: 6689-702. PMID 22672002 DOI: 10.1021/Jo300635M  0.787
2011 Guo P, Joo JM, Rakshit S, Sames D. C-H arylation of pyridines: high regioselectivity as a consequence of the electronic character of C-H bonds and heteroarene ring. Journal of the American Chemical Society. 133: 16338-41. PMID 21939181 DOI: 10.1021/Ja206022P  0.415
2011 Lee M, Tremblay MS, Jockusch S, Turro NJ, Sames D. Intermolecular energy transfer from Tb3+ to Eu3+ in aqueous aggregates and on the surface of human cells. Organic Letters. 13: 2802-5. PMID 21563789 DOI: 10.1021/Ol200328P  0.598
2010 Rodriguez PC, Yee DJ, Sames D. Expanding the use of fluorogenic enzyme reporter substrates to imaging metabolic flux changes: the activity measurement of 5α-steroid reductase in intact mammalian cells. Acs Chemical Biology. 5: 1045-52. PMID 20863068 DOI: 10.1021/Cb100196N  0.777
2010 Muirhead KE, Froemming M, Li X, Musilek K, Conway SJ, Sames D, Gunn-Moore FJ. (-)-CHANA, a fluorogenic probe for detecting amyloid binding alcohol dehydrogenase HSD10 activity in living cells. Acs Chemical Biology. 5: 1105-14. PMID 20836522 DOI: 10.1021/Cb100199M  0.765
2010 Joo JM, Touré BB, Sames D. C-H bonds as ubiquitous functionality: a general approach to complex arylated imidazoles via regioselective sequential arylation of all three C-H bonds and regioselective N-alkylation enabled by SEM-group transposition. The Journal of Organic Chemistry. 75: 4911-20. PMID 20608749 DOI: 10.1021/Jo100727J  0.425
2010 Lee M, Gubernator NG, Sulzer D, Sames D. Development of pH-responsive fluorescent false neurotransmitters. Journal of the American Chemical Society. 132: 8828-30. PMID 20540519 DOI: 10.1021/Ja101740K  0.447
2010 SAMES D, POLT R. ChemInform Abstract: Piperidine Triols via Enantioselective Alkylation and Osmylation of Alanine Schiff Base Esters. Cheminform. 26: no-no. DOI: 10.1002/CHIN.199540222  0.57
2009 Vadola PA, Sames D. C-H bond functionalization via hydride transfer: direct coupling of unactivated alkynes and sp(3) C-H bonds catalyzed by platinum tetraiodide. Journal of the American Chemical Society. 131: 16525-8. PMID 19852462 DOI: 10.1021/Ja906480W  0.804
2009 Zhang H, Gubernator NG, Yue M, Staal RG, Mosharov EV, Pereira D, Balsanek V, Vadola PA, Mukherjee B, Edwards RH, Sulzer D, Sames D. Dopamine release at individual presynaptic terminals visualized with FFNs. Journal of Visualized Experiments : Jove. PMID 19721412 DOI: 10.3791/1562  0.75
2009 McQuaid KM, Long JZ, Sames D. C-H bond functionalization via hydride transfer: synthesis of dihydrobenzopyrans from ortho-vinylaryl akyl ethers. Organic Letters. 11: 2972-5. PMID 19548698 DOI: 10.1021/Ol900915P  0.729
2009 Gubernator NG, Zhang H, Staal RG, Mosharov EV, Pereira DB, Yue M, Balsanek V, Vadola PA, Mukherjee B, Edwards RH, Sulzer D, Sames D. Fluorescent false neurotransmitters visualize dopamine release from individual presynaptic terminals. Science (New York, N.Y.). 324: 1441-4. PMID 19423778 DOI: 10.1126/Science.1172278  0.751
2009 Goikhman R, Jacques TL, Sames D. C-H bonds as ubiquitous functionality: a general approach to complex arylated pyrazoles via sequential regioselective C-arylation and N-alkylation enabled by SEM-group transposition. Journal of the American Chemical Society. 131: 3042-8. PMID 19206533 DOI: 10.1021/Ja8096114  0.801
2009 McQuaid KM, Sames D. C-H bond functionalization via hydride transfer: Lewis acid catalyzed alkylation reactions by direct intramolecular coupling of sp3 C-H bonds and reactive alkenyl oxocarbenium intermediates. Journal of the American Chemical Society. 131: 402-3. PMID 19099474 DOI: 10.1021/Ja806068H  0.743
2008 Halim M, Yee DJ, Sames D. Imaging induction of cytoprotective enzymes in intact human cells: coumberone, a metabolic reporter for human AKR1C enzymes reveals activation by panaxytriol, an active component of red ginseng. Journal of the American Chemical Society. 130: 14123-8. PMID 18826220 DOI: 10.1021/Ja801245Y  0.785
2008 Tremblay MS, Lee M, Sames D. A luminescent sensor for tyrosine phosphorylation. Organic Letters. 10: 5-8. PMID 18069839 DOI: 10.1021/Ol701920X  0.597
2007 Froemming MK, Sames D. Harnessing functional plasticity of enzymes: a fluorogenic probe for imaging 17beta-HSD10 dehydrogenase, an enzyme involved in Alzheimer's and Parkinson's diseases. Journal of the American Chemical Society. 129: 14518-22. PMID 17958419 DOI: 10.1021/Ja072601X  0.768
2007 Gribkov DV, Pastine SJ, Schnürch M, Sames D. Ruthenium catalyzed decarbonylative arylation at sp3 carbon centers in pyrrolidine and piperidine heterocycles. Journal of the American Chemical Society. 129: 11750-5. PMID 17803274 DOI: 10.1021/Ja072577N  0.754
2007 Halim M, Tremblay MS, Jockusch S, Turro NJ, Sames D. Transposing molecular fluorescent switches into the near-IR: development of luminogenic reporter substrates for redox metabolism. Journal of the American Chemical Society. 129: 7704-5. PMID 17542585 DOI: 10.1021/Ja071311D  0.585
2007 Tremblay MS, Halim M, Sames D. Cocktails of Tb(3+) and Eu(3+) complexes: a general platform for the design of ratiometric optical probes. Journal of the American Chemical Society. 129: 7570-7. PMID 17518468 DOI: 10.1021/Ja070867Y  0.537
2007 Wang X, Gribkov DV, Sames D. Phosphine-free palladium-catalyzed C-H bond arylation of free (N-H)-indoles and pyrroles. The Journal of Organic Chemistry. 72: 1476-9. PMID 17288392 DOI: 10.1021/Jo061979V  0.388
2007 Sames D, Pastine S, Gribkov D. trans-Selective sp3 C-H Bond Arylation of Pyrrolidines and Piperidines Synfacts. 2007: 0181-0181. DOI: 10.1055/s-2006-955850  0.709
2007 Jockusch S, Zheng Q, He GS, Pudavar HE, Yee DJ, Balsanek V, Halim M, Sames D, Prasad PN, Turro NJ. Two-photon excitation of fluorogenic probes for redox metabolism: Dramatic enhancement of optical contrast ratio by two-photon excitation Journal of Physical Chemistry C. 111: 8872-8877. DOI: 10.1021/Jp067430H  0.77
2007 Lane BS, Brown aMA, Sames D. Direct Palladium-Catalyzed C-2 and C-3 Arylation of Indoles: A Mechanistic Rationale for Regioselectivity [J. Am. Chem. Soc. 2005, 127, 8050−8057]. Journal of the American Chemical Society. 129: 241-241. DOI: 10.1021/Ja0699790  0.344
2006 Pastine SJ, Gribkov DV, Sames D. sp3 C-H bond arylation directed by amidine protecting group: alpha-arylation of pyrrolidines and piperidines. Journal of the American Chemical Society. 128: 14220-1. PMID 17076471 DOI: 10.1021/Ja064481J  0.745
2006 Tremblay MS, Sames D. Synthesis of luminescent heterometallic bis-lanthanide complexes via selective, sequential metallation. Chemical Communications (Cambridge, England). 4116-8. PMID 17024267 DOI: 10.1039/B607949K  0.531
2006 Yee DJ, Balsanek V, Bauman DR, Penning TM, Sames D. Fluorogenic metabolic probes for direct activity readout of redox enzymes: Selective measurement of human AKR1C2 in living cells. Proceedings of the National Academy of Sciences of the United States of America. 103: 13304-9. PMID 16938874 DOI: 10.1073/Pnas.0604672103  0.794
2006 and BS, Sames D. Diversity Synthesis via C−H Bond Functionalization: Concept-Guided Development of New C-Arylation Methods for Imidazoles [J. Am. Chem. Soc. 2003, 125, 10580−10585]. Journal of the American Chemical Society. 128: 8364-8364. PMID 16787104 DOI: 10.1021/Ja0699642  0.346
2006 and BS, Sames D. Selective C-Arylation of Free (NH)-Heteroarenes via Catalytic C−H Bond Functionalization [J. Am. Chem. Soc. 2003, 125, 5274−5275]. Journal of the American Chemical Society. 128: 8364-8364. PMID 16787103 DOI: 10.1021/Ja069965U  0.356
2006 Tremblay MS, Zhu Q, Martí AA, Dyer J, Halim M, Jockusch S, Turro NJ, Sames D. Phosphorylation state-responsive lanthanide peptide conjugates: a luminescence switch based on reversible complex reorganization. Organic Letters. 8: 2723-6. PMID 16774241 DOI: 10.1021/Ol060614U  0.533
2006 Touré BB, Lane BS, Sames D. Catalytic C-H arylation of SEM-protected azoles with palladium complexes of NHCs and phosphines. Organic Letters. 8: 1979-82. PMID 16671761 DOI: 10.1021/Ol053021C  0.37
2006 Godula K, Sames D. C-H bond functionalization in complex organic synthesis. Science (New York, N.Y.). 312: 67-72. PMID 16601184 DOI: 10.1126/Science.1114731  0.706
2006 Sezen B, Sames D. Oxidative C-arylation of free (NH)-heterocycles via direct sp3 C-H bond functionalization [J. Am. Chem. Soc. 2004, 126, 13244-13246]. Journal of the American Chemical Society. 128: 3102. PMID 16506793 DOI: 10.1021/Ja069957D  0.36
2006 Sezen B, Sames D. Selective and catalytic arylation of N-phenylpyrrolidine: (sp3) C-H bond functionalization in the absence of a directing group [J. Am. Chem. Soc. 2005, 127, 5284-5285]. Journal of the American Chemical Society. 128: 3102. PMID 16506792 DOI: 10.1021/Ja0699586  0.371
2006 Froemming MK, Sames D. Fluoromorphic substrates for fatty acid metabolism: highly sensitive probes for mammalian medium-chain acyl-CoA dehydrogenase. Angewandte Chemie (International Ed. in English). 45: 637-42. PMID 16365837 DOI: 10.1002/Anie.200502675  0.758
2006 Godula K, Sezen aB, Sames D. Site-Specific Phenylation of Pyridine Catalyzed by Phosphido-Bridged Ruthenium Dimer Complexes: A Prototype for C−H Arylation of Electron-Deficient Heteroarenes [J. Am. Chem. Soc. 2005, 127, 3648−3649]. Journal of the American Chemical Society. 128: 3102-3102. DOI: 10.1021/Ja069956L  0.648
2005 Pastine SJ, Sames D. Room temperature intramolecular hydro-O-alkylation of aldehydes: sp3 C-H functionalization via a Lewis acid catalyzed tandem 1,5-hydride transfer/cyclization. Organic Letters. 7: 5429-31. PMID 16288523 DOI: 10.1021/Ol0522283  0.741
2005 Pastine SJ, McQuaid KM, Sames D. Room temperature hydroalkylation of electron-deficient olefins: sp3 C-H functionalization via a lewis acid-catalyzed intramolecular redox event. Journal of the American Chemical Society. 127: 12180-1. PMID 16131169 DOI: 10.1021/Ja053337F  0.799
2005 Tremblay MS, Sames D. A new fluorogenic transformation: development of an optical probe for coenzyme Q. Organic Letters. 7: 2417-20. PMID 15932212 DOI: 10.1021/Ol0507569  0.554
2005 Lane BS, Brown MA, Sames D. Direct palladium-catalyzed C-2 and C-3 arylation of indoles: a mechanistic rationale for regioselectivity. Journal of the American Chemical Society. 127: 8050-7. PMID 15926829 DOI: 10.1021/Ja043273T  0.39
2005 Sezen B, Sames D. Selective and catalytic arylation of N-phenylpyrrolidine: sp3 C-H bond functionalization in the absence of a directing group. Journal of the American Chemical Society. 127: 5284-5. PMID 15826142 DOI: 10.1021/Ja050269O  0.384
2005 Wang X, Lane BS, Sames D. Direct C-arylation of free (NH)-indoles and pyrroles catalyzed by Ar-Rh(III) complexes assembled in situ. Journal of the American Chemical Society. 127: 4996-7. PMID 15810815 DOI: 10.1021/Ja050279P  0.372
2005 Chen G, Yee DJ, Gubernator NG, Sames D. Design of optical switches as metabolic indicators: new fluorogenic probes for monoamine oxidases (MAO A and B). Journal of the American Chemical Society. 127: 4544-5. PMID 15796498 DOI: 10.1021/Ja0428457  0.788
2005 Godula K, Sezen B, Sames D. Site-specific phenylation of pyridine catalyzed by phosphido-bridged ruthenium dimer complexes: a prototype for C-H arylation of electron-deficient heteroarenes. Journal of the American Chemical Society. 127: 3648-9. PMID 15771470 DOI: 10.1021/Ja042510P  0.698
2004 Sezen B, Sames D. Oxidative C-arylation of free (NH)-heterocycles via direct (sp3) C-H bond functionalization. Journal of the American Chemical Society. 126: 13244-6. PMID 15479077 DOI: 10.1021/Ja045402B  0.412
2004 Lane BS, Sames D. Direct C-H bond arylation: selective palladium-catalyzed C2-arylation of N-substituted indoles. Organic Letters. 6: 2897-900. PMID 15330642 DOI: 10.1021/Ol0490072  0.387
2004 DeBoef B, Pastine SJ, Sames D. Cross-coupling of sp(3) C-H bonds and alkenes: catalytic cyclization of alkene-amide substrates. Journal of the American Chemical Society. 126: 6556-7. PMID 15161275 DOI: 10.1021/Ja049111E  0.813
2004 Yee DJ, Balsanek V, Sames D. New tools for molecular imaging of redox metabolism: development of a fluorogenic probe for 3 alpha-hydroxysteroid dehydrogenases. Journal of the American Chemical Society. 126: 2282-3. PMID 14982413 DOI: 10.1021/Ja039799F  0.782
2004 Youn SW, Pastine SJ, Sames D. Ru(III)-catalyzed cyclization of arene-alkene substrates via intramolecular electrophilic hydroarylation. Organic Letters. 6: 581-4. PMID 14961628 DOI: 10.1021/ol036385i  0.698
2003 Slovin SF, Ragupathi G, Musselli C, Olkiewicz K, Verbel D, Kuduk SD, Schwarz JB, Sames D, Danishefsky S, Livingston PO, Scher HI. Fully synthetic carbohydrate-based vaccines in biochemically relapsed prostate cancer: clinical trial results with alpha-N-acetylgalactosamine-O-serine/threonine conjugate vaccine. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 21: 4292-8. PMID 14645418 DOI: 10.1200/JCO.2003.04.112  0.491
2003 Pastine SJ, Sames D. Concise synthesis of the chemopreventitive agent (+/-)-deguelin via a key 6-endo hydroarylation. Organic Letters. 5: 4053-5. PMID 14572247 DOI: 10.1021/Ol035419J  0.704
2003 Sezen B, Sames D. Cobalt-catalyzed arylation of azole heteroarenes via direct C-H bond functionalization. Organic Letters. 5: 3607-10. PMID 14507184 DOI: 10.1021/Ol035313O  0.405
2003 Sezen B, Sames D. Diversity synthesis via C-H bond functionalization: concept-guided development of new C-arylation methods for imidazoles. Journal of the American Chemical Society. 125: 10580-5. PMID 12940740 DOI: 10.1021/Ja036157J  0.399
2003 Chen G, Heim A, Riether D, Yee D, Milgrom Y, Gawinowicz MA, Sames D. Reactivity of functional groups on the protein surface: development of epoxide probes for protein labeling. Journal of the American Chemical Society. 125: 8130-3. PMID 12837082 DOI: 10.1021/Ja034287M  0.774
2003 Sezen B, Sames D. Selective C-arylation of free (NH)-heteroarenes via catalytic C-H bond functionalization. Journal of the American Chemical Society. 125: 5274-5. PMID 12720429 DOI: 10.1021/Ja034848+  0.403
2003 Pastine SJ, Youn SW, Sames D. Pt(IV)-catalyzed cyclization of arene-alkyne substrates via intramolecular electrophilic hydroarylation. Organic Letters. 5: 1055-8. PMID 12659572 DOI: 10.1021/Ol034177K  0.713
2003 Pastine SJ, Youn SW, Sames D. Pt(IV)-catalyzed cyclization of arene-alkyne substrates via C-H bond functionalization Tetrahedron. 59: 8859-8868. DOI: 10.1016/J.Tet.2003.05.003  0.733
2002 Sezen B, Franz R, Sames D. C-C bond formation via C-H bond activation: catalytic arylation and alkenylation of alkane segments. Journal of the American Chemical Society. 124: 13372-3. PMID 12418875 DOI: 10.1021/Ja027891Q  0.387
2002 Dangel BD, Godula K, Youn SW, Sezen B, Sames D. C-C bond formation via C-H bond activation: synthesis of the core of teleocidin B4. Journal of the American Chemical Society. 124: 11856-7. PMID 12358522 DOI: 10.1021/Ja027311P  0.797
2002 Coltart DM, Royyuru AK, Williams LJ, Glunz PW, Sames D, Kuduk SD, Schwarz JB, Chen XT, Danishefsky SJ, Live DH. Principles of mucin architecture: structural studies on synthetic glycopeptides bearing clustered mono-, di-, tri-, and hexasaccharide glycodomains. Journal of the American Chemical Society. 124: 9833-44. PMID 12175243 DOI: 10.1021/Ja020208F  0.721
2002 Johnson JA, Li N, Sames D. Total synthesis of (-)-rhazinilam: asymmetric C[bond]H bond activation via the use of a chiral auxiliary. Journal of the American Chemical Society. 124: 6900-3. PMID 12059212 DOI: 10.1021/Ja026130K  0.39
2001 Dangel BD, Johnson JA, Sames D. Selective functionalization of amino acids in water: a synthetic method via catalytic C-H bond activation. Journal of the American Chemical Society. 123: 8149-50. PMID 11506585 DOI: 10.1021/Ja016280F  0.794
2001 Havranek M, Moreira R, Sames D. New fluorogenic probes for oxygen and carbene transfer: a sensitive assay for single bead-supported catalysts. Journal of the American Chemical Society. 123: 3927-31. PMID 11457142 DOI: 10.1021/Ja003786+  0.688
2000 Moreira RF, Wehn PM, Sames D. Highly Regioselective Oxygenation of C-H Bonds: Diamidomanganese Constructs with Attached Substrates as Catalyst Models Financial support has been provided by Columbia University and the Camille and Henry Dreyfus Foundation. P.M.W. acknowledges the REU-NSF program for summer support. We also thank Dr. J. B. Schwarz (manuscript preparation) and Dr. Y. Itagaki (mass spectrometry). Angewandte Chemie (International Ed. in English). 39: 1618-1621. PMID 10820453 DOI: 10.1002/(Sici)1521-3773(20000502)39:9<1618::Aid-Anie1618>3.0.Co;2-M  0.681
2000 Johnson JA, Sames D. C-H bond activation of hydrocarbon segments in complex organic molecules: Total synthesis of the antimitotic rhazinilam [18] Journal of the American Chemical Society. 122: 6321-6322. DOI: 10.1021/Ja0003223  0.35
2000 Moreira R, Wehn P, Sames D. Hoch regioselektive Oxygenierung von CHBindungen: Diamidmangankomplexe mit angebundenem Substrat als Katalysatormodelle Angewandte Chemie. 112: 1696-1699. DOI: 10.1002/(Sici)1521-3757(20000502)112:9<1696::Aid-Ange1696>3.0.Co;2-3  0.637
1999 Ragupathi G, Slovin SF, Adluri S, Sames D, Kim IJ, Kim HM, Spassova M, Bornmann WG, Lloyd KO, Scher HI, Livingston PO, Danishefsky SJ. A Fully Synthetic Globo H Carbohydrate Vaccine Induces a Focused Humoral Response in Prostate Cancer Patients: A Proof of Principle. Angewandte Chemie (International Ed. in English). 38: 563-566. PMID 29711780 DOI: 10.1002/(Sici)1521-3773(19990215)38:4<563::Aid-Anie563>3.0.Co;2-3  0.469
1999 Live DH, Williams LJ, Kuduk SD, Schwarz JB, Glunz PW, Chen XT, Sames D, Kumar RA, Danishefsky SJ. Probing cell-surface architecture through synthesis: an NMR-determined structural motif for tumor-associated mucins. Proceedings of the National Academy of Sciences of the United States of America. 96: 3489-93. PMID 10097062 DOI: 10.1073/Pnas.96.7.3489  0.531
1999 Polt R, Sames D, Chruma J. Glycosidase inhibitors: Synthesis of enantiomerically pure aza-sugars from Schiff base amino esters via tandem reduction-alkenylation and osmylation Journal of Organic Chemistry. 64: 6147-6158. DOI: 10.1021/Jo9820115  0.619
1999 Glunz PW, Hintermann S, Schwarz JB, Kuduk SD, Chen XT, Williams LJ, Sames D, Danishefsky SJ, Kudryashov V, Lloyd KO. Probing cell surface 'glyco-architecture' through total synthesis. Immunological consequences of a human blood group determinant in a clustered mucin-like context [6] Journal of the American Chemical Society. 121: 10636-10637. DOI: 10.1021/Ja992309S  0.533
1999 Schwarz JB, Kuduk SD, Chen XT, Sames D, Glunz PW, Danishefsky SJ. A broadly applicable method for the efficient synthesis of α-O-linked glycopeptides and clustered sialic acid residues Journal of the American Chemical Society. 121: 2662-2673. DOI: 10.1021/Ja9833265  0.545
1999 Ragupathi G, Slovin SF, Adluri S, Sames D, Kim IJ, Kim HM, Spassova M, Bornmann WG, Lloyd KO, Scher HI, Livingston PO, Danishefsky SJ. Ein totalsynthetischer Globo-H-Kohlenhydrat-Impfstoff verursacht eine gezielte humorale Immunantwort bei Prostatakrebs-Patienten: der Beweis des Prinzips Angewandte Chemie. 111: 590-594. DOI: 10.1002/(Sici)1521-3757(19990215)111:4<590::Aid-Ange590>3.0.Co;2-A  0.481
1998 Kuduk SD, Schwarz JB, Chen X, Glunz PW, Sames D, Ragupathi G, Livingston PO, Danishefsky SJ. Synthetic and Immunological Studies on Clustered Modes of Mucin-Related Tn and TF O-Linked Antigens:  The Preparation of a Glycopeptide-Based Vaccine for Clinical Trials against Prostate Cancer† Journal of the American Chemical Society. 120: 12474-12485. DOI: 10.1021/Ja9825128  0.556
1997 Sames D, Chen XT, Danishefsky SJ. Convergent total synthesis of a tumour-associated mucin motif. Nature. 389: 587-91. PMID 9335496 DOI: 10.1038/39292  0.527
1997 Dangel B, Clarke M, Haley J, Sames D, Polt R. Amino acid-derived ligands for transition metals: Catalysis via a minimalist interpretation of a metalloprotein Journal of the American Chemical Society. 119: 10865-10866. DOI: 10.1021/Ja972135J  0.756
1997 Chruma JJ, Sames D, Polt R. General method for the synthesis of N-methyl amino acids and N-alkyl amino esters from O'Donnell's Schiff bases Tetrahedron Letters. 38: 5085-5086. DOI: 10.1016/S0040-4039(97)01132-5  0.597
1995 Sames D, Polt R. Piperidine Triols via Enantioselective Alkylation and Osmylation of Alanine Schiff Base Esters Synlett. 1995: 552-554. DOI: 10.1055/S-1995-5282  0.615
1995 Sames D, Liu Y, DeYoung L, Polt R. Preparation of monosilyl acetals from esters via iBu2AlH reduction and trapping with N-(trimethylsilyl)imidazole. Addition of allyltrimethylsilane to yield homoallylic alcohols or ethers Journal of Organic Chemistry. 60: 2153-2159. DOI: 10.1021/Jo00112A039  0.54
1994 Sames D, Polt R. An enantioselective synthesis of N-methylfucosamine via tandem C-C/C-O bond formation Journal of Organic Chemistry. 59: 4596-4601. DOI: 10.1021/Jo00095A039  0.641
Low-probability matches (unlikely to be authored by this person)
2020 Fiala T, Wang J, Dunn M, Šebej P, Choi SJ, Nwadibia EC, Fialova E, Martinez DM, Cheetham CE, Fogle KJ, Palladino MJ, Freyberg Z, Sulzer D, Sames D. Chemical Targeting of Voltage Sensitive Dyes to Specific Cells and Molecules in the Brain. Journal of the American Chemical Society. PMID 32395989 DOI: 10.1021/Jacs.0C00861  0.296
1998 Chen XT, Sames D, Danishefsky SJ. Exploration of modalities in building α-O-linked systems through glycal assembly: A total synthesis of the mucin-related F1α antigen Journal of the American Chemical Society. 120: 7760-7769. DOI: 10.1021/Ja980724Z  0.293
2006 Sezen B, Franz aR, Sames D. C−C Bond Formation via C−H Bond Activation: Catalytic Arylation and Alkenylation of Alkane Segments [J. Am. Chem. Soc. 2002, 124, 13372−13373]. Journal of the American Chemical Society. 128: 8364-8364. PMID 16787102 DOI: 10.1021/Ja069966M  0.293
2018 Dunn M, Henke A, Clark S, Kovalyova Y, Kempadoo KA, Karpowicz RJ, Kandel ER, Sulzer D, Sames D. Designing a norepinephrine optical tracer for imaging individual noradrenergic synapses and their activity in vivo. Nature Communications. 9: 2838. PMID 30026491 DOI: 10.1038/S41467-018-05075-X  0.288
2017 Dunn M, Boltaev U, Beskow A, Pampou S, Realubit R, Meira T, Silva JV, Reeb R, Karan C, Jockusch S, Sulzer D, Chang YT, Sames D, Waites C. Identification of fluorescent small molecule compounds for synaptic labeling by image-based, high-content screening. Acs Chemical Neuroscience. PMID 29215865 DOI: 10.1021/Acschemneuro.7B00263  0.283
2015 Merchant P, Sulzer D, Sames D. Synaptic optical imaging platforms: Examining pharmacological modulation of neurotransmitter release at discrete synapses. Neuropharmacology. PMID 25837712 DOI: 10.1016/J.Neuropharm.2015.03.013  0.269
2015 Er JC, Leong C, Teoh CL, Yuan Q, Merchant P, Dunn M, Sulzer D, Sames D, Bhinge A, Kim D, Kim SM, Yoon MH, Stanton LW, Je SH, Yun SW, et al. NeuO: a fluorescent chemical probe for live neuron labeling. Angewandte Chemie (International Ed. in English). 54: 2442-6. PMID 25565332 DOI: 10.1002/Anie.201408614  0.265
2013 Sames D, Dunn M, Karpowicz RJ, Sulzer D. Visualizing neurotransmitter secretion at individual synapses. Acs Chemical Neuroscience. 4: 648-51. PMID 23862751 DOI: 10.1021/Cn4000956  0.261
2018 Meszaros J, Cheung T, Erler MM, Kang UJ, Sames D, Kellendonk C, Sulzer D. Evoked transients of pH-sensitive fluorescent false neurotransmitter reveal dopamine hot spots in the globus pallidus. Elife. 7. PMID 30566076 DOI: 10.7554/Elife.42383  0.261
2016 Freyberg Z, Sonders MS, Aguilar JI, Hiranita T, Karam CS, Flores J, Pizzo AB, Zhang Y, Farino ZJ, Chen A, Martin CA, Kopajtic TA, Fei H, Hu G, Lin YY, ... ... Sames D, et al. Mechanisms of amphetamine action illuminated through optical monitoring of dopamine synaptic vesicles in Drosophila brain. Nature Communications. 7: 10652. PMID 26879809 DOI: 10.1038/Ncomms10652  0.259
2019 Kruegel AC, Uprety R, Grinnell SG, Langreck C, Pekarskaya EA, Le Rouzic V, Ansonoff M, Gassaway MM, Pintar JE, Pasternak GW, Javitch JA, Majumdar S, Sames D. 7-Hydroxymitragynine Is an Active Metabolite of Mitragynine and a Key Mediator of Its Analgesic Effects. Acs Central Science. 5: 992-1001. PMID 31263758 DOI: 10.1021/Acscentsci.9B00141  0.259
2017 Aguilar JI, Dunn M, Mingote S, Karam CS, Farino ZJ, Sonders MS, Choi SJ, Grygoruk A, Zhang Y, Cela C, Choi BJ, Flores J, Freyberg RJ, McCabe BD, Mosharov EV, ... ... Sames D, et al. Neuronal Depolarization Drives Increased Dopamine Synaptic Vesicle Loading via VGLUT. Neuron. PMID 28823729 DOI: 10.1016/J.Neuron.2017.07.038  0.251
2016 Kruegel AC, Gassaway MM, Kapoor A, Váradi A, Majumdar S, Filizola M, Javitch JA, Sames D. Synthetic and Receptor Signaling Explorations of the Mitragyna Alkaloids: Mitragynine as an Atypical Molecular Framework for Opioid Receptor Modulators. Journal of the American Chemical Society. PMID 27192616 DOI: 10.1021/Jacs.6B00360  0.246
1999 Havranek M, Singh A, Sames D. Evolution and study of polymer-supported metal catalysts for oxygen atom transfer: Oxidation of alkanes and alkenes by diamide manganese complexes [13] Journal of the American Chemical Society. 121: 8965-8966. DOI: 10.1021/Ja991336F  0.24
2017 Samuels BA, Nautiyal KM, Kruegel AC, Levinstein MR, Magalong VM, Gassaway MM, Grinnell SG, Han J, Ansonoff MA, Pintar JE, Javitch JA, Sames D, Hen R. The Behavioral Effects of the Antidepressant Tianeptine Require the Mu Opioid Receptor. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28303899 DOI: 10.1038/Npp.2017.60  0.239
2005 Dyer J, Jockusch S, Balsanek V, Sames D, Turro NJ. Two-photon induced uncaging of a reactive intermediate. Multiphoton in situ detection of a potentially valuable label for biological applications. The Journal of Organic Chemistry. 70: 2143-7. PMID 15760198 DOI: 10.1021/Jo048053C  0.239
2000 Singh A, Yao Q, Tong L, Still WC, Sames D. Combinatorial approach to the development of fluorescent sensors for nanomolar aqueous copper Tetrahedron Letters. 41: 9601-9605. DOI: 10.1016/S0040-4039(00)01714-7  0.239
1999 Havranek M, Singh A, Sames D. Evolution and Study of Polymer-Supported Metal Catalysts for Oxygen Atom Transfer:  Oxidation of Alkanes and Alkenes by Diamide Manganese Complexes [J. Am. Chem. Soc.1999,121, 8965−8966]. Journal of the American Chemical Society. 121: 10668-10668. DOI: 10.1021/Ja995534I  0.238
2018 Meszaros J, Cheung T, Erler MM, Kang UJ, Sames D, Kellendonk C, Sulzer D. Author response: Evoked transients of pH-sensitive fluorescent false neurotransmitter reveal dopamine hot spots in the globus pallidus Elife. DOI: 10.7554/Elife.42383.020  0.23
2014 Federici M, Latagliata EC, Ledonne A, Rizzo FR, Feligioni M, Sulzer D, Dunn M, Sames D, Gu H, Nisticò R, Puglisi-Allegra S, Mercuri NB. Paradoxical abatement of striatal dopaminergic transmission by cocaine and methylphenidate. The Journal of Biological Chemistry. 289: 264-74. PMID 24280216 DOI: 10.1074/Jbc.M113.495499  0.227
2008 Sezen B, Sames D. What is C-H Bond Activation? Handbook of C-H Transformations: Applications in Organic Synthesis. 1: 2-10. DOI: 10.1002/9783527619450.ch1  0.224
2008 He GS, Qin HY, Zheng Q, Prasad PN, Jockusch S, Turro NJ, Halim M, Sames D, Ågren H, He S. Dynamic properties and optical phase conjugation of two-photon pumped ultrashort blue stimulated emission in a chromophore solution Physical Review a - Atomic, Molecular, and Optical Physics. 77. DOI: 10.1103/Physreva.77.013824  0.211
1990 Pouzar V, Sameš D, Havel M. Preparation of selectively protected derivatives of 21-nor-5-pregnene-3β,20-diol Collection of Czechoslovak Chemical Communications. 55: 499-511. DOI: 10.1135/CCCC19900499  0.195
2007 Sames D, Wang X, Gribkov D. Pd-Catalyzed C-H Activation Route to Aryl Indoles and Pyrroles Synfacts. 2007: 0475-0475. DOI: 10.1055/s-2007-968467  0.193
2008 Murahashi SI, Yamamoto Y, Bajracharya GB, Nicolau C, Oiarbide M, Hamashima Y, Sodeoka M, Córdova A, Snider BB, Yoshimitsu T, Minisci F, Porta O, Stoltz BM, Ebner DC, Ganesan A, ... ... Sames D, et al. C-H Transformation at Functionalized Alkanes Handbook of C-H Transformations: Applications in Organic Synthesis. 2: 317-496. DOI: 10.1002/9783527619450.ch8  0.178
2015 Genovino J, Sames D, Toure BB. ChemInform Abstract: Access to Drug Metabolites via C-H Functionalization: Copper-Catalyzed Aerobic Oxidation of N,N-Dimethylalkylamines in Complex Pharmaceuticals. Cheminform. 46: no-no. DOI: 10.1002/chin.201539162  0.177
2016 Genovino J, Sames D, Hamann LG, Toure BB. ChemInform Abstract: Accessing Drug Metabolites via Transition-Metal Catalyzed C-H Oxidation: The Liver as Synthetic Inspiration Cheminform. 47. DOI: 10.1002/chin.201651252  0.165
2021 Chakraborty S, DiBerto JF, Faouzi A, Bernhard SM, Gutridge AM, Ramsey S, Zhou Y, Provasi D, Nuthikattu N, Jilakara R, Nelson MNF, Asher WB, Eans SO, Wilson LL, Chintala SM, ... ... Sames D, et al. A Novel Mitragynine Analog with Low-Efficacy Mu Opioid Receptor Agonism Displays Antinociception with Attenuated Adverse Effects. Journal of Medicinal Chemistry. PMID 34505767 DOI: 10.1021/acs.jmedchem.1c01273  0.158
2021 Chakraborty S, Uprety R, Slocum ST, Irie T, Le Rouzic V, Li X, Wilson LL, Scouller B, Alder AF, Kruegel AC, Ansonoff M, Varadi A, Eans SO, Hunkele A, Allaoa A, ... ... Sames D, et al. Oxidative Metabolism as a Modulator of Kratom's Biological Actions. Journal of Medicinal Chemistry. PMID 34783240 DOI: 10.1021/acs.jmedchem.1c01111  0.147
2022 Fiala T, Mosharov EV, Wang J, Mendieta AM, Choi SJ, Fialova E, Hwu C, Sulzer D, Sames D. Chemical Targeting of Rhodol Voltage-Sensitive Dyes to Dopaminergic Neurons. Acs Chemical Neuroscience. 13: 1251-1262. PMID 35400149 DOI: 10.1021/acschemneuro.1c00862  0.141
2021 Post MR, Lee WL, Guo J, Sames D, Sulzer D. Development of a Dual Fluorescent and Magnetic Resonance False Neurotransmitter That Reports Accumulation and Release from Dopaminergic Synaptic Vesicles. Acs Chemical Neuroscience. PMID 34817175 DOI: 10.1021/acschemneuro.1c00580  0.133
1990 Pouzar V, Chodounská H, Sameš D, Drašar P, Havel M. Derivatives of 5α-androstan-3α- and 3β-ol with acrylate side chain Collection of Czechoslovak Chemical Communications. 55: 1243-1256. DOI: 10.1135/CCCC19901243  0.127
1990 POUZAR V, SAMES D, HAVEL M. ChemInform Abstract: Steroids. Part 349. Preparation of Selectively Protected Derivatives of 21-Nor-5-pregnene-3β,20-diol. Cheminform. 21. DOI: 10.1002/CHIN.199024287  0.104
2014 Gassaway MM, Rives ML, Kruegel AC, Javitch JA, Sames D. The atypical antidepressant and neurorestorative agent tianeptine is a μ-opioid receptor agonist. Translational Psychiatry. 4: e411. PMID 25026323 DOI: 10.1038/tp.2014.30  0.095
2023 Vidyadhara DJ, Somayaji M, Wade N, Yücel B, Zhao H, Shashaank N, Ribaudo J, Gupta J, Lam TT, Sames D, Greene LE, Sulzer DL, Chandra SS. Dopamine transporter and synaptic vesicle sorting defects underlie auxilin-associated Parkinson's disease. Cell Reports. 42: 112231. PMID 36920906 DOI: 10.1016/j.celrep.2023.112231  0.085
1999 Ragupathi G, Slovin SF, Adluri S, Sames D, Kim IJ, Kim HM, Spassova M, Bornmann WG, Lloyd KO, Scher HI, Livingston PO, Danishefsky SJ. A fully synthetic globo H carbohydrate vaccine induces a focused humoral response in prostate cancer patients: A proof of principle Angewandte Chemie - International Edition. 38: 563-566.  0.065
2010 Kuduk SD, Schwarz JB, Chen X, Glunz PW, Sames D, Ragupathi G, Livingston PO, Danishefsky SJ. ChemInform Abstract: Synthetic and Immunological Studies on Clustered Modes of Mucin-Related Tn and TF O-Linked Antigens: The Preparation of a Glycopeptide-Based Vaccine for Clinical Trials Against Prostate Cancer. Cheminform. 30: no-no. DOI: 10.1002/CHIN.199917232  0.053
1990 POUZAR V, CHODOUNSKA H, SAMES D, DRASAR P, HAVEL M. ChemInform Abstract: Steroids. Part 350. Derivatives of 5α-Androstan-3α- and -3β-ol with Acrylate Side Chain. Cheminform. 21. DOI: 10.1002/CHIN.199038302  0.052
2002 Sames D, Matt B, Neibuhr B, Tally G, Whitmore B, Bakken D. Developing a heterogeneous intrusion tolerant CORBA system Proceedings of the 2002 International Conference On Dependable Systems and Networks. 239-248. DOI: 10.1109/DSN.2002.1028905  0.05
1996 Ernst WE, Farson DF, Sames DJ. Determination of copper in A533b steel for the assessment of radiation embrittlement using laser-induced breakdown spectroscopy Applied Spectroscopy. 50: 306-309.  0.041
2006 Sames DJ, Lehecka TM, Thomas JG. Multiple applications for the 10 kW fiber laser at the Electro-Optics Center Proceedings of Spie - the International Society For Optical Engineering. 6101. DOI: 10.1117/12.649786  0.041
1996 Behr A, Häfner F, Boy S, Wagner S, Sames D. Hydrodynamic examination of forefields of surface mines by means of parameter identification in numerical flow and transport models | Hydrodynamische erkundung von tagebauvorfeldern durch para-meteridentifikation numerischer strömungs - und transport-modelle Prace Naukowe Instytutu Gornictwa Politechniki Wroclawskiej. 23-30.  0.024
1965 Sames D. Linienform der ESR-Spektren. Einfluß der Verschiebungsmatrix Zeitschrift FüR Physik. 188: 108-123. DOI: 10.1007/BF01339399  0.024
1967 Sames D. ESR-Linienbreite der Ionen der Eisengruppe in Lösungen Zeitschrift FüR Physik. 198: 71-78. DOI: 10.1007/BF01326685  0.023
1982 Both J, Gutt B, Kaden S, Luckner L, Sames D. (Rough draft for the GEOFIM program system for the digital simulation of the geofiltration and geomigration of underground water, East Germany). | Konzeption fur das Programmsystem GEOFIM zur digitalen Simulation der Geofiltration und Geomigration des unterirdischen Wassers Wissenschaftliche Zeitschrift - Technischen Universitat, Dresden. 31: 229-233.  0.02
1997 Rose JL, Hongerholt DD, Sames DJ. Laser based, guided wave experiments for tubing Experimental Mechanics. 37: 165-168.  0.018
1966 Pfeifer H, Michel D, Sames D, Sprinz H. Proton magnetic relaxation in dilute solutions of paramagnetic ions Molecular Physics. 11: 591-595. DOI: 10.1080/00268976600101401  0.013
2003 Tally G, Whitmore B, Sames D, Matt B, Niebuhr B, Bakken D. Intrusion tolerant distributed object systems: Project summary Proceedings - Darpa Information Survivability Conference and Exposition, Discex 2003. 2: 149-151. DOI: 10.1109/DISCEX.2003.1194955  0.01
1967 Sames D. Näherungsverfahren zur Auswertung von ESR-Spektren Zeitschrift FüR Physik. 198: 125-131. DOI: 10.1007/BF01326900  0.01
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