Brent R. Stockwell - Publications

Chemistry Columbia University, New York, NY 
to identify compounds and proteins that act as critical regulators of cancer and neurodegeneration

169 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Chen D, Chu B, Yang X, Liu Z, Jin Y, Kon N, Rabadan R, Jiang X, Stockwell BR, Gu W. iPLA2β-mediated lipid detoxification controls p53-driven ferroptosis independent of GPX4. Nature Communications. 12: 3644. PMID 34131139 DOI: 10.1038/s41467-021-23902-6  0.2
2021 Affo S, Nair A, Brundu F, Ravichandra A, Bhattacharjee S, Matsuda M, Chin L, Filliol A, Wen W, Song X, Decker A, Worley J, Caviglia JM, Yu L, Yin D, ... ... Stockwell BR, et al. Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations. Cancer Cell. 39: 883. PMID 34129825 DOI: 10.1016/j.ccell.2021.05.010  0.12
2021 Iketani S, Forouhar F, Liu H, Hong SJ, Lin FY, Nair MS, Zask A, Huang Y, Xing L, Stockwell BR, Chavez A, Ho DD. Author Correction: Lead compounds for the development of SARS-CoV-2 3CL protease inhibitors. Nature Communications. 12: 2708. PMID 33953192 DOI: 10.1038/s41467-021-23082-3  1
2021 Affo S, Nair A, Brundu F, Ravichandra A, Bhattacharjee S, Matsuda M, Chin L, Filliol A, Wen W, Song X, Decker A, Worley J, Caviglia JM, Yu L, Yin D, ... ... Stockwell BR, et al. Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations. Cancer Cell. PMID 33930309 DOI: 10.1016/j.ccell.2021.03.012  0.08
2021 Resnick SJ, Iketani S, Hong SJ, Zask A, Liu H, Kim S, Melore S, Lin FY, Nair MS, Huang Y, Lee S, Tay NES, Rovis T, Yang HW, Xing L, ... Stockwell BR, et al. Inhibitors of coronavirus 3CL proteases protect cells from protease-mediated cytotoxicity. Journal of Virology. PMID 33910954 DOI: 10.1128/JVI.02374-20  1
2021 Iketani S, Forouhar F, Liu H, Hong SJ, Lin FY, Nair MS, Zask A, Huang Y, Xing L, Stockwell BR, Chavez A, Ho DD. Lead compounds for the development of SARS-CoV-2 3CL protease inhibitors. Nature Communications. 12: 2016. PMID 33795671 DOI: 10.1038/s41467-021-22362-2  1
2021 Zhou H, Lin S, Li X, Guo D, Wang Y, Hu Y. Serum miR-222 is independently associated with atrial fibrillation in patients with degenerative valvular heart disease. Bmc Cardiovascular Disorders. 21: 98. PMID 33593281 DOI: 10.1186/s12872-021-01909-7  0.32
2021 Jiang X, Stockwell BR, Conrad M. Ferroptosis: mechanisms, biology and role in disease. Nature Reviews. Molecular Cell Biology. PMID 33495651 DOI: 10.1038/s41580-020-00324-8  0.2
2020 Anthonymuthu TS, Tyurina YY, Sun WY, Mikulska-Ruminska K, Shrivastava IH, Tyurin VA, Cinemre FB, Dar HH, VanDemark AP, Holman TR, Sadovsky Y, Stockwell BR, He RR, Bahar I, Bayır H, et al. Resolving the paradox of ferroptotic cell death: Ferrostatin-1 binds to 15LOX/PEBP1 complex, suppresses generation of peroxidized ETE-PE, and protects against ferroptosis. Redox Biology. 38: 101744. PMID 33126055 DOI: 10.1016/j.redox.2020.101744  0.08
2020 Venkatesh D, Stockwell BR, Prives C. p21 can be a barrier to ferroptosis independent of p53. Aging. 12: 17800-17814. PMID 32979260 DOI: 10.18632/aging.103961  1
2020 Resnick SJ, Iketani S, Hong SJ, Zask A, Liu H, Kim S, Melore S, Nair MS, Huang Y, Tay NES, Rovis T, Yang HW, Stockwell BR, Ho DD, Chavez A. A simplified cell-based assay to identify coronavirus 3CL protease inhibitors. Biorxiv : the Preprint Server For Biology. PMID 32869020 DOI: 10.1101/2020.08.29.272864  1
2020 Iketani S, Forouhar F, Liu H, Hong SJ, Lin FY, Nair MS, Zask A, Huang Y, Xing L, Stockwell BR, Chavez A, Ho DD. Lead compounds for the development of SARS-CoV-2 3CL protease inhibitors. Biorxiv : the Preprint Server For Biology. PMID 32793898 DOI: 10.1101/2020.08.03.235291  1
2020 Stokes ME, Small JC, Vasciaveo A, Shimada K, Hirschhorn T, Califano A, Stockwell BR. Mesenchymal subtype neuroblastomas are addicted to TGF-βR2/HMGCR-driven protein geranylgeranylation. Scientific Reports. 10: 10748. PMID 32612149 DOI: 10.1038/S41598-020-67310-0  1
2020 Hadian K, Stockwell BR. SnapShot: Ferroptosis. Cell. 181: 1188-1188.e1. PMID 32470402 DOI: 10.1016/j.cell.2020.04.039  0.01
2020 Stockwell BR, Jiang X, Gu W. Emerging Mechanisms and Disease Relevance of Ferroptosis. Trends in Cell Biology. 30: 478-490. PMID 32413317 DOI: 10.1016/J.Tcb.2020.02.009  0.2
2020 Werth EG, Rajbhandari P, Stockwell BR, Brown LM. Time Course of Changes in Sorafenib-Treated Hepatocellular Carcinoma (HCC) Cells Suggests Involvement of Phospho-Regulated Signaling in Ferroptosis Induction. Proteomics. e2000006. PMID 32336023 DOI: 10.1002/Pmic.202000006  1
2020 Stockwell BR, Jiang X. The Chemistry and Biology of Ferroptosis. Cell Chemical Biology. PMID 32294465 DOI: 10.1016/J.Chembiol.2020.03.013  0.24
2020 Badgley MA, Kremer DM, Maurer HC, DelGiorno KE, Lee HJ, Purohit V, Sagalovskiy IR, Ma A, Kapilian J, Firl CEM, Decker AR, Sastra SA, Palermo CF, Andrade LR, Sajjakulnukit P, ... ... Stockwell BR, et al. Cysteine depletion induces pancreatic tumor ferroptosis in mice. Science (New York, N.Y.). 368: 85-89. PMID 32241947 DOI: 10.1126/Science.Aaw9872  1
2020 Feng H, Schorpp K, Jin J, Yozwiak CE, Hoffstrom BG, Decker AM, Rajbhandari P, Stokes ME, Bender HG, Csuka JM, Upadhyayula PS, Canoll P, Uchida K, Soni RK, Hadian K, ... Stockwell BR, et al. Transferrin Receptor Is a Specific Ferroptosis Marker. Cell Reports. 30: 3411-3423.e7. PMID 32160546 DOI: 10.1016/J.Celrep.2020.02.049  1
2020 Venkatesh D, O'Brien NA, Zandkarimi F, Tong DR, Stokes ME, Dunn DE, Kengmana ES, Aron AT, Klein AM, Csuka JM, Moon SH, Conrad M, Chang CJ, Lo DC, D'Alessandro A, ... ... Stockwell BR, et al. MDM2 and MDMX promote ferroptosis by PPARα-mediated lipid remodeling. Genes & Development. PMID 32079652 DOI: 10.1101/Gad.334219.119  1
2020 Ye LF, Reznik E, Korn JM, Lin F, Yang G, Malesky K, Gao H, Loo A, Pagliarini R, Mikkelsen T, Lo DC, deCarvalho AC, Stockwell BR. Patient-derived glioblastoma cultures as a tool for small-molecule drug discovery. Oncotarget. 11: 443-451. PMID 32064048 DOI: 10.18632/Oncotarget.27457  1
2020 Lee H, Zandkarimi F, Zhang Y, Meena JK, Kim J, Zhuang L, Tyagi S, Ma L, Westbrook TF, Steinberg GR, Nakada D, Stockwell BR, Gan B. Energy-stress-mediated AMPK activation inhibits ferroptosis. Nature Cell Biology. 22: 225-234. PMID 32029897 DOI: 10.1038/S41556-020-0461-8  1
2020 Kraft VAN, Bezjian CT, Pfeiffer S, Ringelstetter L, Müller C, Zandkarimi F, Merl-Pham J, Bao X, Anastasov N, Kössl J, Brandner S, Daniels JD, Schmitt-Kopplin P, Hauck SM, Stockwell BR, et al. GTP Cyclohydrolase 1/Tetrahydrobiopterin Counteract Ferroptosis through Lipid Remodeling. Acs Central Science. 6: 41-53. PMID 31989025 DOI: 10.1021/Acscentsci.9B01063  1
2020 Ye LF, Chaudhary KR, Zandkarimi F, Harken AD, Kinslow CJ, Upadhyayula PS, Dovas A, Higgins DM, Tan H, Zhang Y, Buonanno M, Wang TJC, Hei TK, Bruce JN, Canoll PD, ... ... Stockwell BR, et al. Radiation-Induced Lipid Peroxidation Triggers Ferroptosis and Synergizes with Ferroptosis Inducers. Acs Chemical Biology. PMID 31899616 DOI: 10.1021/Acschembio.9B00939  1
2019 Cable J, Finley L, Tu BP, Patti GJ, Oliver TG, Vardhana S, Mana M, Ericksen R, Khare S, DeBerardinis R, Stockwell BR, Edinger A, Haigis M, Kaelin W. Leveraging insights into cancer metabolism-a symposium report. Annals of the New York Academy of Sciences. PMID 31792987 DOI: 10.1111/Nyas.14274  0.01
2019 Stockwell BR. A powerful cell-protection system prevents cell death by ferroptosis. Nature. 575: 597-598. PMID 31768036 DOI: 10.1038/D41586-019-03145-8  0.01
2019 Stockwell BR. Dawn of a New Era of Targeted Antioxidant Therapies. Cell Chemical Biology. 26: 1483-1485. PMID 31756330 DOI: 10.1016/J.Chembiol.2019.11.003  0.01
2019 Bos PH, Lowry ER, Costa J, Thams S, Garcia-Diaz A, Zask A, Wichterle H, Stockwell BR. Development of MAP4 Kinase Inhibitors as Motor Neuron-Protecting Agents. Cell Chemical Biology. PMID 31676236 DOI: 10.1016/J.Chembiol.2019.10.005  1
2019 Wu J, Minikes AM, Gao M, Bian H, Li Y, Stockwell BR, Chen ZN, Jiang X. Publisher Correction: Intercellular interaction dictates cancer cell ferroptosis via NF2-YAP signalling. Nature. PMID 31371811 DOI: 10.1038/S41586-019-1480-0  0.08
2019 Wu J, Minikes AM, Gao M, Bian H, Li Y, Stockwell BR, Chen ZN, Jiang X. Intercellular interaction dictates cancer cell ferroptosis via NF2-YAP signalling. Nature. PMID 31341276 DOI: 10.1038/S41586-019-1426-6  0.16
2019 Stockwell BR, Jiang X. A Physiological Function for Ferroptosis in Tumor Suppression by the Immune System. Cell Metabolism. 30: 14-15. PMID 31269423 DOI: 10.1016/J.Cmet.2019.06.012  0.2
2019 Feng H, Zhang Y, Bos PH, Chambers JM, Dupont MM, Stockwell BR. K-Ras has a potential allosteric small molecule binding site. Biochemistry. PMID 31042025 DOI: 10.1021/Acs.Biochem.8B01300  1
2019 Zhang Y, Tan H, Daniels JD, Zandkarimi F, Liu H, Brown LM, Uchida K, O'Connor OA, Stockwell BR. Imidazole Ketone Erastin Induces Ferroptosis and Slows Tumor Growth in a Mouse Lymphoma Model. Cell Chemical Biology. PMID 30799221 DOI: 10.1016/J.Chembiol.2019.01.008  1
2019 Dieck C, Reglero-Gomez C, Zask A, Stockwell B, Ferrando A. Abstract C005: NT5C2 small molecule inhibitor for the reversal of 6-MP resistance in acute lymphoblastic leukemia Molecular Cancer Therapeutics. 18. DOI: 10.1158/1535-7163.Targ-19-C005  1
2018 Thams S, Lowry ER, Larraufie MH, Spiller KJ, Li H, Williams DJ, Hoang P, Jiang E, Williams LA, Sandoe J, Eggan K, Lieberam I, Kanning KC, Stockwell BR, Henderson CE, et al. A Stem Cell-Based Screening Platform Identifies Compounds that Desensitize Motor Neurons to Endoplasmic Reticulum Stress. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 30446391 DOI: 10.1016/J.Ymthe.2018.10.010  1
2018 Hirschhorn T, Stockwell BR. The Development of the Concept of Ferroptosis. Free Radical Biology & Medicine. PMID 30268886 DOI: 10.1016/J.Freeradbiomed.2018.09.043  0.01
2018 Wang C, Aleksandrov AA, Yang Z, Forouhar F, Proctor EA, Kota P, An J, Kaplan A, Khazanov N, Boël G, Stockwell BR, Senderowitz H, Dokholyan NV, Riordan JR, Brouillette CG, et al. Ligand binding to a remote site thermodynamically corrects the F508del mutation in the human cystic fibrosis transmembrane conductance regulator. The Journal of Biological Chemistry. PMID 29903914 DOI: 10.1074/Jbc.Ra117.000819  1
2018 Conrad M, Kagan VE, Bayir H, Pagnussat GC, Head B, Traber MG, Stockwell BR. Regulation of lipid peroxidation and ferroptosis in diverse species. Genes & Development. 32: 602-619. PMID 29802123 DOI: 10.1101/Gad.314674.118  0.01
2018 Feng H, Stockwell BR. Unsolved mysteries: How does lipid peroxidation cause ferroptosis? Plos Biology. 16: e2006203. PMID 29795546 DOI: 10.1371/Journal.Pbio.2006203  0.12
2018 Youssef LA, Rebbaa A, Pampou S, Weisberg SP, Stockwell BR, Hod EA, Spitalnik SL. Increased erythrophagocytosis induces ferroptosis in red pulp macrophages in a mouse model of transfusion. Blood. PMID 29666112 DOI: 10.1182/Blood-2017-12-822619  0.04
2018 Gaschler MM, Andia AA, Liu H, Csuka JM, Hurlocker B, Vaiana CA, Heindel DW, Zuckerman DS, Bos PH, Reznik E, Ye LF, Tyurina YY, Lin AJ, Shchepinov MS, Chan AY, ... ... Stockwell BR, et al. FINOinitiates ferroptosis through GPX4 inactivation and iron oxidation. Nature Chemical Biology. PMID 29610484 DOI: 10.1038/S41589-018-0031-6  1
2018 Liu H, Schreiber SL, Stockwell BR. Targeting Dependency on the GPX4 Lipid Peroxide Repair Pathway for Cancer Therapy. Biochemistry. PMID 29584411 DOI: 10.1021/Acs.Biochem.8B00307  1
2018 Agmon E, Solon J, Bassereau P, Stockwell BR. Modeling the effects of lipid peroxidation during ferroptosis on membrane properties. Scientific Reports. 8: 5155. PMID 29581451 DOI: 10.1038/S41598-018-23408-0  0.01
2018 Shimada K, Reznik E, Stokes ME, Krishnamoorthy L, Bos PH, Song Y, Quartararo CE, Pagano NC, Carpizo DR, deCarvalho AC, Lo DC, Stockwell BR. Copper-Binding Small Molecule Induces Oxidative Stress and Cell-Cycle Arrest in Glioblastoma-Patient-Derived Cells. Cell Chemical Biology. PMID 29576531 DOI: 10.1016/J.Chembiol.2018.02.010  1
2018 Gaschler MM, Hu F, Feng H, Linkermann A, Min W, Stockwell BR. Determination of the subcellular localization and mechanism of action of ferrostatins in suppressing ferroptosis. Acs Chemical Biology. PMID 29512999 DOI: 10.1021/Acschembio.8B00199  1
2018 Zhou X, Li G, Kaplan A, Gaschler MM, Zhang X, Hou Z, Mali J, Zott R, Cremers S, Stockwell BR, Duan W. Small molecule modulator of protein disulfide isomerase attenuates mutant huntingtin toxicity and inhibits endoplasmic reticulum stress in a mouse model of Huntington's disease. Human Molecular Genetics. PMID 29462355 DOI: 10.1093/Hmg/Ddy061  1
2018 Yozwiak CE, Hirschhorn T, Stockwell BR. Towards a microparticle-based system for pooled assays of small molecules in cellular contexts. Acs Chemical Biology. PMID 29365249 DOI: 10.1021/Acschembio.8B00043  0.01
2018 Galluzzi L, Vitale I, Aaronson SA, Abrams JM, Adam D, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Annicchiarico-Petruzzelli M, Antonov AV, Arama E, Baehrecke EH, Barlev NA, ... ... Stockwell BR, et al. Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. Cell Death and Differentiation. PMID 29362479 DOI: 10.1038/S41418-017-0012-4  1
2018 Zhang Y, Larraufie MH, Musavi L, Akkiraju H, Brown LM, Stockwell BR. Design of small molecules that compete with nucleotide binding to an engineered oncogenic KRAS allele. Biochemistry. PMID 29313669 DOI: 10.1021/Acs.Biochem.7B01113  1
2017 Ye LF, Stockwell BR. Transforming Lipoxygenases: PE-Specific Enzymes in Disguise. Cell. 171: 501-502. PMID 29053966 DOI: 10.1016/J.Cell.2017.10.006  0.4
2017 Stockwell BR, Friedmann Angeli JP, Bayir H, Bush AI, Conrad M, Dixon SJ, Fulda S, Gascón S, Hatzios SK, Kagan VE, Noel K, Jiang X, Linkermann A, Murphy ME, Overholtzer M, et al. Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease. Cell. 171: 273-285. PMID 28985560 DOI: 10.1016/J.Cell.2017.09.021  1
2017 Figuera-Losada M, Thomas AG, Stathis M, Stockwell BR, Rojas C, Slusher BS. Development of a primary microglia screening assay and its use to characterize inhibition of system xc(-) by erastin and its analogs. Biochemistry and Biophysics Reports. 9: 266-272. PMID 28956014 DOI: 10.1016/J.Bbrep.2016.12.009  1
2017 Stockwell BR, Stockwell MS, Jiang E. Group Problem Solving in Class Improves Undergraduate Learning. Acs Central Science. 3: 614-620. PMID 28691073 DOI: 10.1021/Acscentsci.7B00133  1
2017 Viswanathan VS, Ryan MJ, Dhruv HD, Gill S, Eichhoff OM, Seashore-Ludlow B, Kaffenberger SD, Eaton JK, Shimada K, Aguirre AJ, Viswanathan SR, Chattopadhyay S, Tamayo P, Yang WS, Rees MG, ... ... Stockwell BR, et al. Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway. Nature. PMID 28678785 DOI: 10.1038/Nature23007  1
2017 Agmon E, Stockwell BR. Lipid homeostasis and regulated cell death. Current Opinion in Chemical Biology. 39: 83-89. PMID 28645028 DOI: 10.1016/J.Cbpa.2017.06.002  0.01
2017 Linkermann A, Stockwell BR, Vanden Berghe T. Heavy Metal Suicide. American Journal of Physiology. Renal Physiology. ajprenal.00273.2017. PMID 28566503 DOI: 10.1152/Ajprenal.00273.2017  1
2017 Müller T, Dewitz C, Schmitz J, Schröder AS, Bräsen JH, Stockwell BR, Murphy JM, Kunzendorf U, Krautwald S. Necroptosis and ferroptosis are alternative cell death pathways that operate in acute kidney failure. Cellular and Molecular Life Sciences : Cmls. PMID 28551825 DOI: 10.1007/S00018-017-2547-4  1
2017 Li Q, Han X, Lan X, Gao Y, Wan J, Durham F, Cheng T, Yang J, Wang Z, Jiang C, Ying M, Koehler RC, Stockwell BR, Wang J. Inhibition of neuronal ferroptosis protects hemorrhagic brain. Jci Insight. 2: e90777. PMID 28405617 DOI: 10.1172/Jci.Insight.90777  0.4
2017 Welsch ME, Kaplan A, Chambers JM, Stokes ME, Bos PH, Zask A, Zhang Y, Sanchez-Martin M, Badgley MA, Huang CS, Tran TH, Akkiraju H, Brown LM, Nandakumar R, Cremers S, ... ... Stockwell BR, et al. Multivalent Small-Molecule Pan-RAS Inhibitors. Cell. 168: 878-889.e29. PMID 28235199 DOI: 10.1016/J.Cell.2017.02.006  1
2017 Gaschler MM, Stockwell BR. Lipid peroxidation in cell death. Biochemical and Biophysical Research Communications. 482: 419-425. PMID 28212725 DOI: 10.1016/J.Bbrc.2016.10.086  1
2017 Distéfano AM, Martin MV, Córdoba JP, Bellido AM, D'Ippólito S, Colman SL, Soto D, Roldán JA, Bartoli CG, Zabaleta EJ, Fiol DF, Stockwell BR, Dixon SJ, Pagnussat GC. Heat stress induces ferroptosis-like cell death in plants. The Journal of Cell Biology. PMID 28100685 DOI: 10.1083/Jcb.201605110  1
2016 Kagan VE, Mao G, Qu F, Angeli JP, Doll S, Croix CS, Dar HH, Liu B, Tyurin VA, Ritov VB, Kapralov AA, Amoscato AA, Jiang J, Anthonymuthu T, Mohammadyani D, ... ... Stockwell BR, et al. Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis. Nature Chemical Biology. PMID 27842066 DOI: 10.1038/Nchembio.2238  0.01
2016 Kinghorn AD, DE Blanco EJ, Lucas DM, Rakotondraibe HL, Orjala J, Soejarto DD, Oberlies NH, Pearce CJ, Wani MC, Stockwell BR, Burdette JE, Swanson SM, Fuchs JR, Phelps MA, Xu L, et al. Discovery of Anticancer Agents of Diverse Natural Origin. Anticancer Research. 36: 5623-5637. PMID 27793884 DOI: 10.21873/Anticanres.11146  0.12
2016 Krainz T, Gaschler MM, Lim C, Sacher JR, Stockwell BR, Wipf P. A Mitochondrial-Targeted Nitroxide Is a Potent Inhibitor of Ferroptosis. Acs Central Science. 2: 653-659. PMID 27725964 DOI: 10.1021/Acscentsci.6B00199  1
2016 Freyer JL, Brucks SD, Gobieski GS, Russell ST, Yozwiak CE, Sun M, Chen Z, Jiang Y, Bandar JS, Stockwell BR, Lambert TH, Campos LM. Clickable Poly(ionic liquids): A Materials Platform for Transfection. Angewandte Chemie (International Ed. in English). PMID 27578602 DOI: 10.1002/Anie.201605214  0.01
2016 Yang WS, Kim KJ, Gaschler MM, Patel M, Shchepinov MS, Stockwell BR. Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis. Proceedings of the National Academy of Sciences of the United States of America. PMID 27506793 DOI: 10.1073/Pnas.1603244113  1
2016 Gerhard DS, Clemons PA, Shamji AF, Hon C, Wagner BK, Schreiber SL, Krasnitz A, Sordella R, Sander C, Lowe SW, Powers S, Smith K, Aburi M, Iavarone A, Lasorella A, ... ... Stockwell BR, et al. Transforming Big Data into cancer-relevant insight: An initial, multi-tier approach to assess reproducibility and relevance. Molecular Cancer Research : McR. PMID 27401613 DOI: 10.1158/1541-7786.Mcr-16-0090  1
2016 Li H, Kuwajima T, Oakley D, Nikulina E, Hou J, Yang WS, Lowry ER, Lamas NJ, Amoroso MW, Croft GF, Hosur R, Wichterle H, Sebti S, Filbin MT, Stockwell B, et al. Protein Prenylation Constitutes an Endogenous Brake on Axonal Growth. Cell Reports. PMID 27373155 DOI: 10.1016/J.Celrep.2016.06.013  1
2016 Shimada K, Stockwell BR. tRNA synthase suppression activates de novo cysteine synthesis to compensate for cystine and glutathione deprivation during ferroptosis. Molecular & Cellular Oncology. 3: e1091059. PMID 27308611 DOI: 10.1080/23723556.2015.1091059  1
2016 Shimada K, Skouta R, Kaplan A, Yang WS, Hayano M, Dixon SJ, Brown LM, Valenzuela CA, Wolpaw AJ, Stockwell BR. Global survey of cell death mechanisms reveals metabolic regulation of ferroptosis. Nature Chemical Biology. PMID 27159577 DOI: 10.1038/Nchembio.2079  1
2016 Klionsky DJ, Abdelmohsen K, Abe A, Abedin J, Abeliovich H, Arozena AA, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Stockwell BR, et al. Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356 Autophagy. 12: 443-443. PMID 26902590 DOI: 10.1080/15548627.2016.1147886  1
2016 Shimada K, Hayano M, Pagano NC, Stockwell BR. Cell-Line Selectivity Improves the Predictive Power of Pharmacogenomic Analyses and Helps Identify NADPH as Biomarker for Ferroptosis Sensitivity. Cell Chemical Biology. PMID 26853626 DOI: 10.1016/J.Chembiol.2015.11.016  1
2016 Conrad M, Angeli JP, Vandenabeele P, Stockwell BR. Regulated necrosis: disease relevance and therapeutic opportunities. Nature Reviews. Drug Discovery. PMID 26775689 DOI: 10.1038/Nrd.2015.6  1
2016 Badgley MA, Palermo CF, Sastra SA, Stockwell BR, Olive KP. Abstract A41: Leveraging metabolic dependencies in cancer: Cysteine addiction in pancreatic cancer cells Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Metca15-A41  1
2015 Yang WS, Stockwell BR. Ferroptosis: Death by Lipid Peroxidation. Trends in Cell Biology. PMID 26653790 DOI: 10.1016/J.Freeradbiomed.2018.04.034  1
2015 Kaplan A, Stockwell BR. Structural Elucidation of a Small Molecule Inhibitor of Protein Disulfide Isomerase. Acs Medicinal Chemistry Letters. 6: 966-971. PMID 26500720 DOI: 10.1021/Acsmedchemlett.5B00014  1
2015 Stockwell BR, Stockwell MS, Cennamo M, Jiang E. Blended Learning Improves Science Education. Cell. 162: 933-6. PMID 26317458 DOI: 10.1016/J.Cell.2015.08.009  1
2015 Quartararo CE, Reznik E, deCarvalho AC, Mikkelsen T, Stockwell BR. High-Throughput Screening of Patient-Derived Cultures Reveals Potential for Precision Medicine in Glioblastoma. Acs Medicinal Chemistry Letters. 6: 948-52. PMID 26288699 DOI: 10.1021/Acsmedchemlett.5B00128  1
2015 Larraufie MH, Yang WS, Jiang E, Thomas AG, Slusher BS, Stockwell BR. Incorporation of metabolically stable ketones into a small molecule probe to increase potency and water solubility. Bioorganic & Medicinal Chemistry Letters. 25: 4787-92. PMID 26231156 DOI: 10.1016/J.Bmcl.2015.07.018  1
2015 Woo JH, Shimoni Y, Yang WS, Subramaniam P, Iyer A, Nicoletti P, Rodríguez Martínez M, López G, Mattioli M, Realubit R, Karan C, Stockwell BR, Bansal M, Califano A. Elucidating Compound Mechanism of Action by Network Perturbation Analysis. Cell. 162: 441-51. PMID 26186195 DOI: 10.1016/J.Cell.2015.05.056  1
2015 Hayano M, Yang WS, Corn CK, Pagano NC, Stockwell BR. Loss of cysteinyl-tRNA synthetase (CARS) induces the transsulfuration pathway and inhibits ferroptosis induced by cystine deprivation. Cell Death and Differentiation. PMID 26184909 DOI: 10.1038/Cdd.2015.93  1
2015 Bertozzi CR, Stockwell BR, Kubicek S, Dickinson BC, Chang CJ, Schultz C, Silver PA, Gestwicki JE, Chiosis G, Chattopadhyay A, Butcher RA, Park SB, Shoichet BK, Flitsch SL, Zhang J, et al. Voices of chemical biology Nature Chemical Biology. 11: 378-379. PMID 25978987 DOI: 10.1038/Nchembio.1820  0.01
2015 Dixon SJ, Winter GE, Musavi LS, Lee ED, Snijder B, Rebsamen M, Superti-Furga G, Stockwell BR. Human Haploid Cell Genetics Reveals Roles for Lipid Metabolism Genes in Nonapoptotic Cell Death. Acs Chemical Biology. PMID 25965523 DOI: 10.1021/Acschembio.5B00245  1
2015 Kaplan A, Gaschler MM, Dunn DE, Colligan R, Brown LM, Palmer AG, Lo DC, Stockwell BR. Small molecule-induced oxidation of protein disulfide isomerase is neuroprotective. Proceedings of the National Academy of Sciences of the United States of America. 112: E2245-52. PMID 25848045 DOI: 10.1073/Pnas.1500439112  1
2015 Hayano M, Yang WS, Corn CK, Pagano NC, Stockwell BR. Loss of cysteinyl-tRNA synthetase (CARS) induces the transsulfuration pathway and inhibits ferroptosis induced by cystine deprivation Cell Death and Differentiation. DOI: 10.1038/cdd.2015.93  1
2015 Quartararo CE, Reznik E, DeCarvalho AC, Mikkelsen T, Stockwell BR. High-Throughput Screening of Patient-Derived Cultures Reveals Potential for Precision Medicine in Glioblastoma Acs Medicinal Chemistry Letters. 6: 948-952. DOI: 10.1021/acsmedchemlett.5b00128  1
2015 Kaplan A, Stockwell BR. Structural elucidation of a small molecule inhibitor of protein disulfide isomerase Acs Medicinal Chemistry Letters. 6: 966-971. DOI: 10.1021/acsmedchemlett.5b00014  1
2015 Woo JH, Shimoni Y, Yang WS, Subramaniam P, Iyer A, Nicoletti P, Rodríguez Martínez M, López G, Mattioli M, Realubit R, Karan C, Stockwell BR, Bansal M, Califano A. Elucidating Compound Mechanism of Action by Network Perturbation Analysis Cell. 162: 441-451. DOI: 10.1016/j.cell.2015.05.056  1
2014 Friedmann Angeli JP, Schneider M, Proneth B, Tyurina YY, Tyurin VA, Hammond VJ, Herbach N, Aichler M, Walch A, Eggenhofer E, Basavarajappa D, RÃ¥dmark O, Kobayashi S, Seibt T, Beck H, ... ... Stockwell BR, et al. Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice. Nature Cell Biology. 16: 1180-91. PMID 25402683 DOI: 10.1038/Ncb3064  1
2014 Linkermann A, Skouta R, Himmerkus N, Mulay SR, Dewitz C, De Zen F, Prokai A, Zuchtriegel G, Krombach F, Welz PS, Weinlich R, Vanden Berghe T, Vandenabeele P, Pasparakis M, Bleich M, ... ... Stockwell BR, et al. Synchronized renal tubular cell death involves ferroptosis. Proceedings of the National Academy of Sciences of the United States of America. 111: 16836-41. PMID 25385600 DOI: 10.1073/Pnas.1415518111  1
2014 Linkermann A, Stockwell BR, Krautwald S, Anders HJ. Regulated cell death and inflammation: an auto-amplification loop causes organ failure. Nature Reviews. Immunology. 14: 759-67. PMID 25324125 DOI: 10.1038/Nri3743  1
2014 Julien O, Kampmann M, Bassik MC, Zorn JA, Venditto VJ, Shimbo K, Agard NJ, Shimada K, Rheingold AL, Stockwell BR, Weissman JS, Wells JA. Unraveling the mechanism of cell death induced by chemical fibrils. Nature Chemical Biology. 10: 969-76. PMID 25262416 DOI: 10.1038/Nchembio.1639  1
2014 Wolpaw AJ, Stockwell BR. Multidimensional profiling in the investigation of small-molecule-induced cell death. Methods in Enzymology. 545: 265-302. PMID 25065894 DOI: 10.1016/B978-0-12-801430-1.00011-1  1
2014 Cantley AM, Welsch M, Ambesi-Impiombato A, Sanchez-Martin M, Kim MY, Bauer A, Ferrando A, Stockwell BR. Small Molecule that Reverses Dexamethasone Resistance in T-cell Acute Lymphoblastic Leukemia (T-ALL). Acs Medicinal Chemistry Letters. 5: 754-9. PMID 25050160 DOI: 10.1021/Ml500044G  1
2014 Dixon SJ, Patel DN, Welsch M, Skouta R, Lee ED, Hayano M, Thomas AG, Gleason CE, Tatonetti NP, Slusher BS, Stockwell BR. Pharmacological inhibition of cystine-glutamate exchange induces endoplasmic reticulum stress and ferroptosis. Elife. 3: e02523. PMID 24844246 DOI: 10.7554/Elife.02523  1
2014 Skouta R, Dixon SJ, Wang J, Dunn DE, Orman M, Shimada K, Rosenberg PA, Lo DC, Weinberg JM, Linkermann A, Stockwell BR. Ferrostatins inhibit oxidative lipid damage and cell death in diverse disease models. Journal of the American Chemical Society. 136: 4551-6. PMID 24592866 DOI: 10.1021/Ja411006A  1
2014 Yang WS, SriRamaratnam R, Welsch ME, Shimada K, Skouta R, Viswanathan VS, Cheah JH, Clemons PA, Shamji AF, Clish CB, Brown LM, Girotti AW, Cornish VW, Schreiber SL, Stockwell BR. Regulation of ferroptotic cancer cell death by GPX4. Cell. 156: 317-31. PMID 24439385 DOI: 10.1016/J.Cell.2013.12.010  1
2014 Dixon SJ, Stockwell BR. The role of iron and reactive oxygen species in cell death. Nature Chemical Biology. 10: 9-17. PMID 24346035 DOI: 10.1038/Nchembio.1416  1
2014 Dixon SJ, Patel DN, Welsch M, Skouta R, Lee ED, Hayano M, Thomas AG, Gleason CE, Tatonetti NP, Slusher BS, Stockwell BR. Author response: Pharmacological inhibition of cystine–glutamate exchange induces endoplasmic reticulum stress and ferroptosis Elife. DOI: 10.7554/Elife.02523.018  1
2013 Basu A, Bodycombe NE, Cheah JH, Price EV, Liu K, Schaefer GI, Ebright RY, Stewart ML, Ito D, Wang S, Bracha AL, Liefeld T, Wawer M, Gilbert JC, Wilson AJ, ... ... Stockwell BR, et al. An interactive resource to identify cancer genetic and lineage dependencies targeted by small molecules. Cell. 154: 1151-61. PMID 23993102 DOI: 10.1016/J.Cell.2013.08.003  1
2013 Varma H, Gangadhar NM, Letso RR, Wolpaw AJ, Sriramaratnam R, Stockwell BR. Identification of a small molecule that induces ATG5-and-cathepsin-l-dependent cell death and modulates polyglutamine toxicity. Experimental Cell Research. 319: 1759-73. PMID 23588206 DOI: 10.1016/J.Yexcr.2013.03.019  1
2013 Letso RR, Bauer AJ, Lunn MR, Yang WS, Stockwell BR. Small molecule screen reveals regulation of survival motor neuron protein abundance by Ras proteins. Acs Chemical Biology. 8: 914-22. PMID 23496866 DOI: 10.1021/Cb300374H  1
2012 Kosuri P, Alegre-Cebollada J, Feng J, Kaplan A, Inglés-Prieto A, Badilla CL, Stockwell BR, Sanchez-Ruiz JM, Holmgren A, Fernández JM. Protein folding drives disulfide formation. Cell. 151: 794-806. PMID 23141538 DOI: 10.1016/J.Cell.2012.09.036  1
2012 Kaplan A, Stockwell BR. Therapeutic approaches to preventing cell death in Huntington disease. Progress in Neurobiology. 99: 262-80. PMID 22967354 DOI: 10.1016/J.Pneurobio.2012.08.004  1
2012 Skouta R, Hayano M, Shimada K, Stockwell BR. Design and synthesis of Pictet-Spengler condensation products that exhibit oncogenic-RAS synthetic lethality and induce non-apoptotic cell death. Bioorganic & Medicinal Chemistry Letters. 22: 5707-13. PMID 22832321 DOI: 10.1016/J.Bmcl.2012.06.077  1
2012 Dixon SJ, Lemberg KM, Lamprecht MR, Skouta R, Zaitsev EM, Gleason CE, Patel DN, Bauer AJ, Cantley AM, Yang WS, Morrison B, Stockwell BR. Ferroptosis: an iron-dependent form of nonapoptotic cell death. Cell. 149: 1060-72. PMID 22632970 DOI: 10.1016/J.Cell.2012.03.042  1
2012 Weïwer M, Bittker JA, Lewis TA, Shimada K, Yang WS, MacPherson L, Dandapani S, Palmer M, Stockwell BR, Schreiber SL, Munoz B. Development of small-molecule probes that selectively kill cells induced to express mutant RAS. Bioorganic & Medicinal Chemistry Letters. 22: 1822-6. PMID 22297109 DOI: 10.1016/J.Bmcl.2011.09.047  1
2012 Yang WS, Shimada K, Delva D, Patel M, Ode E, Skouta R, Stockwell BR. Identification of Simple Compounds with Microtubule-Binding Activity That Inhibit Cancer Cell Growth with High Potency. Acs Medicinal Chemistry Letters. 3: 35-38. PMID 22247791 DOI: 10.1021/Ml200195S  1
2012 Kanning KC, Li H, Nikulina E, Hou J, Yang WS, Kaplan A, Bermingham JR, Lamas NJ, Amoroso MW, Wichterle H, Filbin MT, Stockwell B, Henderson CE. Making motor axons grow International Journal of Developmental Neuroscience. 30: 613-614. DOI: 10.1016/J.Ijdevneu.2012.10.106  1
2011 Herman AG, Hayano M, Poyurovsky MV, Shimada K, Skouta R, Prives C, Stockwell BR. Discovery of Mdm2-MdmX E3 ligase inhibitors using a cell-based ubiquitination assay. Cancer Discovery. 1: 312-25. PMID 22586610 DOI: 10.1158/2159-8290.Cd-11-0104  1
2011 Wolpaw AJ, Shimada K, Skouta R, Welsch ME, Akavia UD, Pe'er D, Shaik F, Bulinski JC, Stockwell BR. Modulatory profiling identifies mechanisms of small molecule-induced cell death. Proceedings of the National Academy of Sciences of the United States of America. 108: E771-80. PMID 21896738 DOI: 10.1073/Pnas.1106149108  1
2011 Bauer AJ, Gieschler S, Lemberg KM, McDermott AE, Stockwell BR. Functional model of metabolite gating by human voltage-dependent anion channel 2. Biochemistry. 50: 3408-10. PMID 21425834 DOI: 10.1021/Bi2003247  1
2011 Stockwell BR. Understanding the role of disturbance in peri-urban agricultural systems and communities: New concepts and principles to guide strategic intervention International Journal of Innovation and Sustainable Development. 5: 389-402. DOI: 10.1504/IJISD.2011.043337  1
2010 Hoffstrom BG, Kaplan A, Letso R, Schmid RS, Turmel GJ, Lo DC, Stockwell BR. Inhibitors of protein disulfide isomerase suppress apoptosis induced by misfolded proteins. Nature Chemical Biology. 6: 900-6. PMID 21079601 DOI: 10.1038/Nchembio.467  1
2010 Varma H, Yamamoto A, Sarantos MR, Hughes RE, Stockwell BR. Mutant huntingtin alters cell fate in response to microtubule depolymerization via the GEF-H1-RhoA-ERK pathway. The Journal of Biological Chemistry. 285: 37445-57. PMID 20858895 DOI: 10.1074/Jbc.M110.125542  1
2010 Schreiber SL, Shamji AF, Clemons PA, Hon C, Koehler AN, Munoz B, Palmer M, Stern AM, Wagner BK, Powers S, Lowe SW, Guo X, Krasnitz A, Sawey ET, ... ... Stockwell BR, et al. Towards patient-based cancer therapeutics. Nature Biotechnology. 28: 904-6. PMID 20829823 DOI: 10.1038/Nbt0910-904  1
2010 Dixon SJ, Stockwell BR. Drug discovery: engineering drug combinations. Nature Chemical Biology. 6: 318-9. PMID 20404820 DOI: 10.1038/Nchembio.353  1
2010 Welsch ME, Snyder SA, Stockwell BR. Privileged scaffolds for library design and drug discovery. Current Opinion in Chemical Biology. 14: 347-61. PMID 20303320 DOI: 10.1016/J.Cbpa.2010.02.018  1
2009 Dixon SJ, Stockwell BR. Identifying druggable disease-modifying gene products. Current Opinion in Chemical Biology. 13: 549-55. PMID 19740696 DOI: 10.1016/J.Cbpa.2009.08.003  1
2009 Yen L, Stockwell BR, Mulligan RC. A mammalian cell-based assay for screening inhibitors of RNA cleavage. Methods in Molecular Biology (Clifton, N.J.). 540: 335-47. PMID 19381571 DOI: 10.1007/978-1-59745-558-9_24  1
2008 Lehár J, Stockwell BR, Giaever G, Nislow C. Combination chemical genetics. Nature Chemical Biology. 4: 674-81. PMID 18936752 DOI: 10.1038/Nchembio.120  1
2008 Gangadhar NM, Firestein SJ, Stockwell BR. A novel role for jun N-terminal kinase signaling in olfactory sensory neuronal death. Molecular and Cellular Neurosciences. 38: 518-25. PMID 18571430 DOI: 10.1016/J.Mcn.2008.04.013  1
2008 Yang WS, Stockwell BR. Inhibition of casein kinase 1-epsilon induces cancer-cell-selective, PERIOD2-dependent growth arrest. Genome Biology. 9: R92. PMID 18518968 DOI: 10.1186/Gb-2008-9-6-R92  1
2008 Bauer AJ, Stockwell BR. Neurobiological applications of small molecule screening Chemical Reviews. 108: 1774-1786. PMID 18447397 DOI: 10.1021/Cr0782372  1
2008 Yang WS, Stockwell BR. Synthetic lethal screening identifies compounds activating iron-dependent, nonapoptotic cell death in oncogenic-RAS-harboring cancer cells. Chemistry & Biology. 15: 234-45. PMID 18355723 DOI: 10.1016/J.Chembiol.2008.02.010  1
2008 Varma H, Lo DC, Stockwell BR. High throughput screening for neurodegeneration and complex disease phenotypes. Combinatorial Chemistry & High Throughput Screening. 11: 238-48. PMID 18336216 DOI: 10.2174/138620708783877753  1
2008 Antipova AA, Stockwell BR, Golub TR. Gene expression-based screening for inhibitors of PDGFR signaling. Genome Biology. 9: R47. PMID 18312689 DOI: 10.1186/Gb-2008-9-3-R47  1
2007 Varma H, Cheng R, Voisine C, Hart AC, Stockwell BR. Inhibitors of metabolism rescue cell death in Huntington's disease models. Proceedings of the National Academy of Sciences of the United States of America. 104: 14525-30. PMID 17726098 DOI: 10.1073/Pnas.0704482104  1
2007 Yagoda N, von Rechenberg M, Zaganjor E, Bauer AJ, Yang WS, Fridman DJ, Wolpaw AJ, Smukste I, Peltier JM, Boniface JJ, Smith R, Lessnick SL, Sahasrabudhe S, Stockwell BR. RAS-RAF-MEK-dependent oxidative cell death involving voltage-dependent anion channels. Nature. 447: 864-8. PMID 17568748 DOI: 10.1038/Nature05859  1
2007 Voisine C, Varma H, Walker N, Bates EA, Stockwell BR, Hart AC. Identification of potential therapeutic drugs for huntington's disease using Caenorhabditis elegans. Plos One. 2: e504. PMID 17551584 DOI: 10.1371/Journal.Pone.0000504  1
2007 Lehár J, Zimmermann GR, Krueger AS, Molnar RA, Ledell JT, Heilbut AM, Short GF, Giusti LC, Nolan GP, Magid OA, Lee MS, Borisy AA, Stockwell BR, Keith CT. Chemical combination effects predict connectivity in biological systems. Molecular Systems Biology. 3: 80. PMID 17332758 DOI: 10.1038/Msb4100116  1
2007 Varma H, Voisine C, DeMarco CT, Cattaneo E, Lo DC, Hart AC, Stockwell BR. Selective inhibitors of death in mutant huntingtin cells. Nature Chemical Biology. 3: 99-100. PMID 17195849 DOI: 10.1038/Nchembio852  1
2007 Gangadhar NM, Stockwell BR. Chemical genetic approaches to probing cell death. Current Opinion in Chemical Biology. 11: 83-7. PMID 17174591 DOI: 10.1016/J.Cbpa.2006.11.033  1
2006 Letso RR, Stockwell BR. Chemical biology: renewing embryonic stem cells. Nature. 444: 692-3. PMID 17151647 DOI: 10.1038/444692B  1
2006 Herman AG, Stockwell BR. Enzyme annotation with chemical tools. Chemistry & Biology. 13: 1013-4. PMID 17052604 DOI: 10.1016/J.Chembiol.2006.10.002  1
2006 Desai UA, Pallos J, Ma AA, Stockwell BR, Thompson LM, Marsh JL, Diamond MI. Biologically active molecules that reduce polyglutamine aggregation and toxicity. Human Molecular Genetics. 15: 2114-24. PMID 16720620 DOI: 10.1093/Hmg/Ddl135  1
2006 Moffat J, Grueneberg DA, Yang X, Kim SY, Kloepfer AM, Hinkle G, Piqani B, Eisenhaure TM, Luo B, Grenier JK, Carpenter AE, Foo SY, Stewart SA, Stockwell BR, Hacohen N, et al. A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen. Cell. 124: 1283-98. PMID 16564017 DOI: 10.1016/J.Cell.2006.01.040  1
2006 Yen L, Magnier M, Weissleder R, Stockwell BR, Mulligan RC. Identification of inhibitors of ribozyme self-cleavage in mammalian cells via high-throughput screening of chemical libraries. Rna (New York, N.Y.). 12: 797-806. PMID 16556935 DOI: 10.1261/Rna.2300406  1
2006 Smukste I, Bhalala O, Persico M, Stockwell BR. Using small molecules to overcome drug resistance induced by a viral oncogene. Cancer Cell. 9: 133-46. PMID 16473280 DOI: 10.1016/J.Ccr.2006.01.012  1
2006 Stockwell BR. Preventing protein secretion with chemical glue. Nature Chemical Biology. 2: 7-8. PMID 16408080 DOI: 10.1038/Nchembio0106-7  1
2005 Lunn MR, Stockwell BR. Chemical genetics and orphan genetic diseases. Chemistry & Biology. 12: 1063-73. PMID 16242649 DOI: 10.1016/J.Chembiol.2005.09.005  1
2005 Smukste I, Stockwell BR. Advances in chemical genetics. Annual Review of Genomics and Human Genetics. 6: 261-86. PMID 16124862 DOI: 10.1146/Annurev.Genom.6.080604.162136  1
2005 Keith CT, Borisy AA, Stockwell BR. Multicomponent therapeutics for networked systems. Nature Reviews. Drug Discovery. 4: 71-8. PMID 15688074 DOI: 10.1038/Nrd1609  1
2004 Stockwell BR. Exploring biology with small organic molecules. Nature. 432: 846-54. PMID 15602550 DOI: 10.1038/Nature03196  1
2004 Kelley BP, Lunn MR, Root DE, Flaherty SP, Martino AM, Stockwell BR. A flexible data analysis tool for chemical genetic screens. Chemistry & Biology. 11: 1495-503. PMID 15556000 DOI: 10.1016/J.Chembiol.2004.08.026  1
2004 Lunn MR, Root DE, Martino AM, Flaherty SP, Kelley BP, Coovert DD, Burghes AH, Man NT, Morris GE, Zhou J, Androphy EJ, Sumner CJ, Stockwell BR. Indoprofen upregulates the survival motor neuron protein through a cyclooxygenase-independent mechanism. Chemistry & Biology. 11: 1489-93. PMID 15555999 DOI: 10.1016/J.Chembiol.2004.08.024  1
2004 Bailey SN, Sabatini DM, Stockwell BR. Microarrays of small molecules embedded in biodegradable polymers for use in mammalian cell-based screens. Proceedings of the National Academy of Sciences of the United States of America. 101: 16144-9. PMID 15534212 DOI: 10.1073/Pnas.0404425101  1
2004 Kelley BP, Yuan B, Lewitter F, Sharan R, Stockwell BR, Ideker T. PathBLAST: a tool for alignment of protein interaction networks. Nucleic Acids Research. 32: W83-8. PMID 15215356 DOI: 10.1093/Nar/Gkh411  1
2004 Stegmaier K, Ross KN, Colavito SA, O'Malley S, Stockwell BR, Golub TR. Gene expression-based high-throughput screening(GE-HTS) and application to leukemia differentiation. Nature Genetics. 36: 257-63. PMID 14770183 DOI: 10.1038/Ng1305  1
2004 Stockwell BR. The biological magic behind the bullets. Nature Biotechnology. 22: 37-8. PMID 14704700 DOI: 10.1038/Nbt0104-37  1
2003 Smukste I, Stockwell BR. Restoring functions of tumor suppressors with small molecules. Cancer Cell. 4: 419-20. PMID 14706331 DOI: 10.1016/S1535-6108(03)00307-6  1
2003 Root DE, Kelley BP, Stockwell BR. Detecting spatial patterns in biological array experiments. Journal of Biomolecular Screening. 8: 393-8. PMID 14567791 DOI: 10.1177/1087057103254282  1
2003 Root DE, Flaherty SP, Kelley BP, Stockwell BR. Biological mechanism profiling using an annotated compound library. Chemistry & Biology. 10: 881-92. PMID 14522058 DOI: 10.1016/J.Chembiol.2003.08.009  1
2003 Kelley BP, Sharan R, Karp RM, Sittler T, Root DE, Stockwell BR, Ideker T. Conserved pathways within bacteria and yeast as revealed by global protein network alignment. Proceedings of the National Academy of Sciences of the United States of America. 100: 11394-9. PMID 14504397 DOI: 10.1073/Pnas.1534710100  1
2003 Borisy AA, Elliott PJ, Hurst NW, Lee MS, Lehar J, Price ER, Serbedzija G, Zimmermann GR, Foley MA, Stockwell BR, Keith CT. Systematic discovery of multicomponent therapeutics. Proceedings of the National Academy of Sciences of the United States of America. 100: 7977-82. PMID 12799470 DOI: 10.1073/Pnas.1337088100  0.44
2003 Dolma S, Lessnick SL, Hahn WC, Stockwell BR. Identification of genotype-selective antitumor agents using synthetic lethal chemical screening in engineered human tumor cells. Cancer Cell. 3: 285-96. PMID 12676586 DOI: 10.1016/S1535-6108(03)00050-3  1
2002 Stockwell BR. Chemical genetic screening approaches to neurobiology. Neuron. 36: 559-62. PMID 12441046 DOI: 10.1016/S0896-6273(02)01056-5  1
2002 Root DE, Kelley BP, Stockwell BR. Global analysis of large-scale chemical and biological experiments. Current Opinion in Drug Discovery & Development. 5: 355-60. PMID 12058610  1
2002 Blanchard BJ, Stockwell BR, Ingram VM. Eliminating membrane depolarization caused by the Alzheimer peptide Abeta(1-42, aggr.). Biochemical and Biophysical Research Communications. 293: 1204-8. PMID 12054503 DOI: 10.1016/S0006-291X(02)00290-5  1
2000 Stockwell BR. Chemical genetics: ligand-based discovery of gene function. Nature Reviews. Genetics. 1: 116-25. PMID 11253651 DOI: 10.1038/35038557  1
2000 Stockwell BR. Frontiers in chemical genetics. Trends in Biotechnology. 18: 449-55. PMID 11058785 DOI: 10.1016/S0167-7799(00)01499-2  1
2000 Walters MA, Tan DS, Foley MA, Stockwell BR, Shair MD, Schreiber SL. Synthesis and preliminary evaluation of a library of polycyclic small molecules for use in chemical genetic assays Chemtracts. 13: 268-275. DOI: 10.1021/Ja992144N  1
2000 Walters MA, Tan DS, Foley MA, Stockwell BR, Shair MD, Schreiber SL. Synthesis and preliminary evaluation of a library of polycyclic small molecules for use in chemical genetic assays Chemtracts. 13: 268-275.  1
1999 Stockwell BR, Haggarty SJ, Schreiber SL. High-throughput screening of small molecules in miniaturized mammalian cell-based assays involving post-translational modifications. Chemistry & Biology. 6: 71-83. PMID 10021420 DOI: 10.1016/S1074-5521(99)80004-0  1
1999 Stockwell BR, Hardwick JS, Tong JK, Schreiber SL. Chemical genetic and genomic approaches reveal a role for copper in specific gene activation [19] Journal of the American Chemical Society. 121: 10662-10663. DOI: 10.1021/Ja9921221  1
1998 Stockwell BR, Schreiber SL. TGF-beta-signaling with small molecule FKBP12 antagonists that bind myristoylated FKBP12-TGF-beta type I receptor fusion proteins. Chemistry & Biology. 5: 385-95. PMID 9662508 DOI: 10.1016/S1074-5521(98)90072-2  1
1998 Stockwell BR, Schreiber SL. Probing the role of homomeric and heteromeric receptor interactions in TGF-beta signaling using small molecule dimerizers. Current Biology : Cb. 8: 761-70. PMID 9651680 DOI: 10.1016/S0960-9822(98)70299-4  1
1998 Muzio M, Stockwell BR, Stennicke HR, Salvesen GS, Dixit VM. An induced proximity model for caspase-8 activation. The Journal of Biological Chemistry. 273: 2926-30. PMID 9446604 DOI: 10.1074/Jbc.273.5.2926  1
1997 Morgan B, Stockwell BR, Dodds DR, Andrews DR, Sudhakar AR, Nielsen CM, Mergelsberg I, Zumbach A. Chemoenzymatic approaches to SCH 56592, a new azole antifungal Jaocs, Journal of the American Oil Chemists' Society. 74: 1361-1370. DOI: 10.1007/S11746-997-0238-2  1
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