| Year |
Citation |
Score |
| 2023 |
Stokes ME, Vasciaveo A, Small JC, Zask A, Reznik E, Smith N, Wang Q, Daniels J, Forouhar F, Rajbhandari P, Califano A, Stockwell BR. Subtype-selective prenylated isoflavonoids disrupt regulatory drivers of MYCN-amplified cancers. Cell Chemical Biology. PMID 38061356 DOI: 10.1016/j.chembiol.2023.11.007 |
0.36 |
|
| 2023 |
Hadian K, Stockwell BR. The therapeutic potential of targeting regulated non-apoptotic cell death. Nature Reviews. Drug Discovery. 22: 723-742. PMID 37550363 DOI: 10.1038/s41573-023-00749-8 |
0.356 |
|
| 2020 |
Stokes ME, Small JC, Vasciaveo A, Shimada K, Hirschhorn T, Califano A, Stockwell BR. Mesenchymal subtype neuroblastomas are addicted to TGF-βR2/HMGCR-driven protein geranylgeranylation. Scientific Reports. 10: 10748. PMID 32612149 DOI: 10.1038/S41598-020-67310-0 |
0.472 |
|
| 2020 |
Stockwell BR, Jiang X, Gu W. Emerging Mechanisms and Disease Relevance of Ferroptosis. Trends in Cell Biology. 30: 478-490. PMID 32413317 DOI: 10.1016/J.Tcb.2020.02.009 |
0.411 |
|
| 2020 |
Stockwell BR, Jiang X. The Chemistry and Biology of Ferroptosis. Cell Chemical Biology. PMID 32294465 DOI: 10.1016/J.Chembiol.2020.03.013 |
0.449 |
|
| 2020 |
Badgley MA, Kremer DM, Maurer HC, DelGiorno KE, Lee HJ, Purohit V, Sagalovskiy IR, Ma A, Kapilian J, Firl CEM, Decker AR, Sastra SA, Palermo CF, Andrade LR, Sajjakulnukit P, ... ... Stockwell BR, et al. Cysteine depletion induces pancreatic tumor ferroptosis in mice. Science (New York, N.Y.). 368: 85-89. PMID 32241947 DOI: 10.1126/Science.Aaw9872 |
0.363 |
|
| 2020 |
Feng H, Schorpp K, Jin J, Yozwiak CE, Hoffstrom BG, Decker AM, Rajbhandari P, Stokes ME, Bender HG, Csuka JM, Upadhyayula PS, Canoll P, Uchida K, Soni RK, Hadian K, ... Stockwell BR, et al. Transferrin Receptor Is a Specific Ferroptosis Marker. Cell Reports. 30: 3411-3423.e7. PMID 32160546 DOI: 10.1016/J.Celrep.2020.02.049 |
0.316 |
|
| 2020 |
Venkatesh D, O'Brien NA, Zandkarimi F, Tong DR, Stokes ME, Dunn DE, Kengmana ES, Aron AT, Klein AM, Csuka JM, Moon SH, Conrad M, Chang CJ, Lo DC, D'Alessandro A, ... ... Stockwell BR, et al. MDM2 and MDMX promote ferroptosis by PPARα-mediated lipid remodeling. Genes & Development. PMID 32079652 DOI: 10.1101/Gad.334219.119 |
0.363 |
|
| 2020 |
Ye LF, Reznik E, Korn JM, Lin F, Yang G, Malesky K, Gao H, Loo A, Pagliarini R, Mikkelsen T, Lo DC, deCarvalho AC, Stockwell BR. Patient-derived glioblastoma cultures as a tool for small-molecule drug discovery. Oncotarget. 11: 443-451. PMID 32064048 DOI: 10.18632/Oncotarget.27457 |
0.37 |
|
| 2020 |
Lee H, Zandkarimi F, Zhang Y, Meena JK, Kim J, Zhuang L, Tyagi S, Ma L, Westbrook TF, Steinberg GR, Nakada D, Stockwell BR, Gan B. Energy-stress-mediated AMPK activation inhibits ferroptosis. Nature Cell Biology. 22: 225-234. PMID 32029897 DOI: 10.1038/S41556-020-0461-8 |
0.332 |
|
| 2020 |
Kraft VAN, Bezjian CT, Pfeiffer S, Ringelstetter L, Müller C, Zandkarimi F, Merl-Pham J, Bao X, Anastasov N, Kössl J, Brandner S, Daniels JD, Schmitt-Kopplin P, Hauck SM, Stockwell BR, et al. GTP Cyclohydrolase 1/Tetrahydrobiopterin Counteract Ferroptosis through Lipid Remodeling. Acs Central Science. 6: 41-53. PMID 31989025 DOI: 10.1021/Acscentsci.9B01063 |
0.419 |
|
| 2020 |
Ye LF, Chaudhary KR, Zandkarimi F, Harken AD, Kinslow CJ, Upadhyayula PS, Dovas A, Higgins DM, Tan H, Zhang Y, Buonanno M, Wang TJC, Hei TK, Bruce JN, Canoll PD, ... ... Stockwell BR, et al. Radiation-Induced Lipid Peroxidation Triggers Ferroptosis and Synergizes with Ferroptosis Inducers. Acs Chemical Biology. PMID 31899616 DOI: 10.1021/Acschembio.9B00939 |
0.371 |
|
| 2019 |
Cable J, Finley L, Tu BP, Patti GJ, Oliver TG, Vardhana S, Mana M, Ericksen R, Khare S, DeBerardinis R, Stockwell BR, Edinger A, Haigis M, Kaelin W. Leveraging insights into cancer metabolism-a symposium report. Annals of the New York Academy of Sciences. PMID 31792987 DOI: 10.1111/Nyas.14274 |
0.356 |
|
| 2019 |
Stockwell BR. A powerful cell-protection system prevents cell death by ferroptosis. Nature. 575: 597-598. PMID 31768036 DOI: 10.1038/D41586-019-03145-8 |
0.406 |
|
| 2019 |
Stockwell BR. Dawn of a New Era of Targeted Antioxidant Therapies. Cell Chemical Biology. 26: 1483-1485. PMID 31756330 DOI: 10.1016/J.Chembiol.2019.11.003 |
0.367 |
|
| 2019 |
Bos PH, Lowry ER, Costa J, Thams S, Garcia-Diaz A, Zask A, Wichterle H, Stockwell BR. Development of MAP4 Kinase Inhibitors as Motor Neuron-Protecting Agents. Cell Chemical Biology. PMID 31676236 DOI: 10.1016/J.Chembiol.2019.10.005 |
0.751 |
|
| 2019 |
Wu J, Minikes AM, Gao M, Bian H, Li Y, Stockwell BR, Chen ZN, Jiang X. Intercellular interaction dictates cancer cell ferroptosis via NF2-YAP signalling. Nature. PMID 31341276 DOI: 10.1038/S41586-019-1426-6 |
0.435 |
|
| 2019 |
Feng H, Zhang Y, Bos PH, Chambers JM, Dupont MM, Stockwell BR. K-Ras has a potential allosteric small molecule binding site. Biochemistry. PMID 31042025 DOI: 10.1021/Acs.Biochem.8B01300 |
0.316 |
|
| 2019 |
Zhang Y, Tan H, Daniels JD, Zandkarimi F, Liu H, Brown LM, Uchida K, O'Connor OA, Stockwell BR. Imidazole Ketone Erastin Induces Ferroptosis and Slows Tumor Growth in a Mouse Lymphoma Model. Cell Chemical Biology. PMID 30799221 DOI: 10.1016/J.Chembiol.2019.01.008 |
0.357 |
|
| 2019 |
Dieck C, Reglero-Gomez C, Zask A, Stockwell B, Ferrando A. Abstract C005: NT5C2 small molecule inhibitor for the reversal of 6-MP resistance in acute lymphoblastic leukemia Molecular Cancer Therapeutics. 18. DOI: 10.1158/1535-7163.Targ-19-C005 |
0.385 |
|
| 2018 |
Thams S, Lowry ER, Larraufie MH, Spiller KJ, Li H, Williams DJ, Hoang P, Jiang E, Williams LA, Sandoe J, Eggan K, Lieberam I, Kanning KC, Stockwell BR, Henderson CE, et al. A Stem Cell-Based Screening Platform Identifies Compounds that Desensitize Motor Neurons to Endoplasmic Reticulum Stress. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 30446391 DOI: 10.1016/J.Ymthe.2018.10.010 |
0.738 |
|
| 2018 |
Hirschhorn T, Stockwell BR. The Development of the Concept of Ferroptosis. Free Radical Biology & Medicine. PMID 30268886 DOI: 10.1016/J.Freeradbiomed.2018.09.043 |
0.404 |
|
| 2018 |
Feng H, Stockwell BR. Unsolved mysteries: How does lipid peroxidation cause ferroptosis? Plos Biology. 16: e2006203. PMID 29795546 DOI: 10.1371/Journal.Pbio.2006203 |
0.396 |
|
| 2018 |
Youssef LA, Rebbaa A, Pampou S, Weisberg SP, Stockwell BR, Hod EA, Spitalnik SL. Increased erythrophagocytosis induces ferroptosis in red pulp macrophages in a mouse model of transfusion. Blood. PMID 29666112 DOI: 10.1182/Blood-2017-12-822619 |
0.311 |
|
| 2018 |
Gaschler MM, Andia AA, Liu H, Csuka JM, Hurlocker B, Vaiana CA, Heindel DW, Zuckerman DS, Bos PH, Reznik E, Ye LF, Tyurina YY, Lin AJ, Shchepinov MS, Chan AY, ... ... Stockwell BR, et al. FINOinitiates ferroptosis through GPX4 inactivation and iron oxidation. Nature Chemical Biology. PMID 29610484 DOI: 10.1038/S41589-018-0031-6 |
0.389 |
|
| 2018 |
Liu H, Schreiber SL, Stockwell BR. Targeting Dependency on the GPX4 Lipid Peroxide Repair Pathway for Cancer Therapy. Biochemistry. PMID 29584411 DOI: 10.1021/Acs.Biochem.8B00307 |
0.481 |
|
| 2018 |
Agmon E, Solon J, Bassereau P, Stockwell BR. Modeling the effects of lipid peroxidation during ferroptosis on membrane properties. Scientific Reports. 8: 5155. PMID 29581451 DOI: 10.1038/S41598-018-23408-0 |
0.341 |
|
| 2018 |
Shimada K, Reznik E, Stokes ME, Krishnamoorthy L, Bos PH, Song Y, Quartararo CE, Pagano NC, Carpizo DR, deCarvalho AC, Lo DC, Stockwell BR. Copper-Binding Small Molecule Induces Oxidative Stress and Cell-Cycle Arrest in Glioblastoma-Patient-Derived Cells. Cell Chemical Biology. PMID 29576531 DOI: 10.1016/J.Chembiol.2018.02.010 |
0.364 |
|
| 2018 |
Gaschler MM, Hu F, Feng H, Linkermann A, Min W, Stockwell BR. Determination of the subcellular localization and mechanism of action of ferrostatins in suppressing ferroptosis. Acs Chemical Biology. PMID 29512999 DOI: 10.1021/Acschembio.8B00199 |
0.367 |
|
| 2018 |
Zhou X, Li G, Kaplan A, Gaschler MM, Zhang X, Hou Z, Mali J, Zott R, Cremers S, Stockwell BR, Duan W. Small molecule modulator of protein disulfide isomerase attenuates mutant huntingtin toxicity and inhibits endoplasmic reticulum stress in a mouse model of Huntington's disease. Human Molecular Genetics. PMID 29462355 DOI: 10.1093/Hmg/Ddy061 |
0.363 |
|
| 2018 |
Yozwiak CE, Hirschhorn T, Stockwell BR. Towards a microparticle-based system for pooled assays of small molecules in cellular contexts. Acs Chemical Biology. PMID 29365249 DOI: 10.1021/Acschembio.8B00043 |
0.36 |
|
| 2018 |
Galluzzi L, Vitale I, Aaronson SA, Abrams JM, Adam D, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Annicchiarico-Petruzzelli M, Antonov AV, Arama E, Baehrecke EH, Barlev NA, ... ... Stockwell BR, et al. Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. Cell Death and Differentiation. PMID 29362479 DOI: 10.1038/S41418-017-0012-4 |
0.406 |
|
| 2017 |
Ye LF, Stockwell BR. Transforming Lipoxygenases: PE-Specific Enzymes in Disguise. Cell. 171: 501-502. PMID 29053966 DOI: 10.1016/J.Cell.2017.10.006 |
0.33 |
|
| 2017 |
Stockwell BR, Friedmann Angeli JP, Bayir H, Bush AI, Conrad M, Dixon SJ, Fulda S, Gascón S, Hatzios SK, Kagan VE, Noel K, Jiang X, Linkermann A, Murphy ME, Overholtzer M, et al. Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease. Cell. 171: 273-285. PMID 28985560 DOI: 10.1016/J.Cell.2017.09.021 |
0.388 |
|
| 2017 |
Figuera-Losada M, Thomas AG, Stathis M, Stockwell BR, Rojas C, Slusher BS. Development of a primary microglia screening assay and its use to characterize inhibition of system xc(-) by erastin and its analogs. Biochemistry and Biophysics Reports. 9: 266-272. PMID 28956014 DOI: 10.1016/J.Bbrep.2016.12.009 |
0.311 |
|
| 2017 |
Viswanathan VS, Ryan MJ, Dhruv HD, Gill S, Eichhoff OM, Seashore-Ludlow B, Kaffenberger SD, Eaton JK, Shimada K, Aguirre AJ, Viswanathan SR, Chattopadhyay S, Tamayo P, Yang WS, Rees MG, ... ... Stockwell BR, et al. Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway. Nature. PMID 28678785 DOI: 10.1038/Nature23007 |
0.77 |
|
| 2017 |
Agmon E, Stockwell BR. Lipid homeostasis and regulated cell death. Current Opinion in Chemical Biology. 39: 83-89. PMID 28645028 DOI: 10.1016/J.Cbpa.2017.06.002 |
0.329 |
|
| 2017 |
Müller T, Dewitz C, Schmitz J, Schröder AS, Bräsen JH, Stockwell BR, Murphy JM, Kunzendorf U, Krautwald S. Necroptosis and ferroptosis are alternative cell death pathways that operate in acute kidney failure. Cellular and Molecular Life Sciences : Cmls. PMID 28551825 DOI: 10.1007/S00018-017-2547-4 |
0.414 |
|
| 2017 |
Li Q, Han X, Lan X, Gao Y, Wan J, Durham F, Cheng T, Yang J, Wang Z, Jiang C, Ying M, Koehler RC, Stockwell BR, Wang J. Inhibition of neuronal ferroptosis protects hemorrhagic brain. Jci Insight. 2: e90777. PMID 28405617 DOI: 10.1172/Jci.Insight.90777 |
0.386 |
|
| 2017 |
Welsch ME, Kaplan A, Chambers JM, Stokes ME, Bos PH, Zask A, Zhang Y, Sanchez-Martin M, Badgley MA, Huang CS, Tran TH, Akkiraju H, Brown LM, Nandakumar R, Cremers S, ... ... Stockwell BR, et al. Multivalent Small-Molecule Pan-RAS Inhibitors. Cell. 168: 878-889.e29. PMID 28235199 DOI: 10.1016/J.Cell.2017.02.006 |
0.346 |
|
| 2017 |
Gaschler MM, Stockwell BR. Lipid peroxidation in cell death. Biochemical and Biophysical Research Communications. 482: 419-425. PMID 28212725 DOI: 10.1016/J.Bbrc.2016.10.086 |
0.359 |
|
| 2017 |
Distéfano AM, Martin MV, Córdoba JP, Bellido AM, D'Ippólito S, Colman SL, Soto D, Roldán JA, Bartoli CG, Zabaleta EJ, Fiol DF, Stockwell BR, Dixon SJ, Pagnussat GC. Heat stress induces ferroptosis-like cell death in plants. The Journal of Cell Biology. PMID 28100685 DOI: 10.1083/Jcb.201605110 |
0.378 |
|
| 2017 |
Stockwell B. FERROPTOSIS: MECHANISMS AND THERAPEUTIC APPLICATIONS Free Radical Biology and Medicine. 112: 7. DOI: 10.1016/J.Freeradbiomed.2017.10.355 |
0.476 |
|
| 2016 |
Kagan VE, Mao G, Qu F, Angeli JP, Doll S, Croix CS, Dar HH, Liu B, Tyurin VA, Ritov VB, Kapralov AA, Amoscato AA, Jiang J, Anthonymuthu T, Mohammadyani D, ... ... Stockwell BR, et al. Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis. Nature Chemical Biology. PMID 27842066 DOI: 10.1038/Nchembio.2238 |
0.357 |
|
| 2016 |
Kinghorn AD, DE Blanco EJ, Lucas DM, Rakotondraibe HL, Orjala J, Soejarto DD, Oberlies NH, Pearce CJ, Wani MC, Stockwell BR, Burdette JE, Swanson SM, Fuchs JR, Phelps MA, Xu L, et al. Discovery of Anticancer Agents of Diverse Natural Origin. Anticancer Research. 36: 5623-5637. PMID 27793884 DOI: 10.21873/Anticanres.11146 |
0.316 |
|
| 2016 |
Krainz T, Gaschler MM, Lim C, Sacher JR, Stockwell BR, Wipf P. A Mitochondrial-Targeted Nitroxide Is a Potent Inhibitor of Ferroptosis. Acs Central Science. 2: 653-659. PMID 27725964 DOI: 10.1021/Acscentsci.6B00199 |
0.408 |
|
| 2016 |
Yang WS, Kim KJ, Gaschler MM, Patel M, Shchepinov MS, Stockwell BR. Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis. Proceedings of the National Academy of Sciences of the United States of America. PMID 27506793 DOI: 10.1073/Pnas.1603244113 |
0.372 |
|
| 2016 |
Gerhard DS, Clemons PA, Shamji AF, Hon C, Wagner BK, Schreiber SL, Krasnitz A, Sordella R, Sander C, Lowe SW, Powers S, Smith K, Aburi M, Iavarone A, Lasorella A, ... ... Stockwell BR, et al. Transforming Big Data into cancer-relevant insight: An initial, multi-tier approach to assess reproducibility and relevance. Molecular Cancer Research : McR. PMID 27401613 DOI: 10.1158/1541-7786.Mcr-16-0090 |
0.767 |
|
| 2016 |
Li H, Kuwajima T, Oakley D, Nikulina E, Hou J, Yang WS, Lowry ER, Lamas NJ, Amoroso MW, Croft GF, Hosur R, Wichterle H, Sebti S, Filbin MT, Stockwell B, et al. Protein Prenylation Constitutes an Endogenous Brake on Axonal Growth. Cell Reports. PMID 27373155 DOI: 10.1016/J.Celrep.2016.06.013 |
0.726 |
|
| 2016 |
Shimada K, Stockwell BR. tRNA synthase suppression activates de novo cysteine synthesis to compensate for cystine and glutathione deprivation during ferroptosis. Molecular & Cellular Oncology. 3: e1091059. PMID 27308611 DOI: 10.1080/23723556.2015.1091059 |
0.395 |
|
| 2016 |
Shimada K, Skouta R, Kaplan A, Yang WS, Hayano M, Dixon SJ, Brown LM, Valenzuela CA, Wolpaw AJ, Stockwell BR. Global survey of cell death mechanisms reveals metabolic regulation of ferroptosis. Nature Chemical Biology. PMID 27159577 DOI: 10.1038/Nchembio.2079 |
0.795 |
|
| 2016 |
Shimada K, Hayano M, Pagano NC, Stockwell BR. Cell-Line Selectivity Improves the Predictive Power of Pharmacogenomic Analyses and Helps Identify NADPH as Biomarker for Ferroptosis Sensitivity. Cell Chemical Biology. PMID 26853626 DOI: 10.1016/J.Chembiol.2015.11.016 |
0.418 |
|
| 2016 |
Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Stockwell BR, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356 |
0.326 |
|
| 2016 |
Conrad M, Angeli JP, Vandenabeele P, Stockwell BR. Regulated necrosis: disease relevance and therapeutic opportunities. Nature Reviews. Drug Discovery. PMID 26775689 DOI: 10.1038/Nrd.2015.6 |
0.438 |
|
| 2016 |
Badgley MA, Palermo CF, Sastra SA, Stockwell BR, Olive KP. Abstract A41: Leveraging metabolic dependencies in cancer: Cysteine addiction in pancreatic cancer cells Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Metca15-A41 |
0.45 |
|
| 2015 |
Yang WS, Stockwell BR. Ferroptosis: Death by Lipid Peroxidation. Trends in Cell Biology. PMID 26653790 DOI: 10.1016/J.Freeradbiomed.2018.04.034 |
0.412 |
|
| 2015 |
Kaplan A, Stockwell BR. Structural Elucidation of a Small Molecule Inhibitor of Protein Disulfide Isomerase. Acs Medicinal Chemistry Letters. 6: 966-971. PMID 26500720 DOI: 10.1021/Acsmedchemlett.5B00014 |
0.381 |
|
| 2015 |
Quartararo CE, Reznik E, deCarvalho AC, Mikkelsen T, Stockwell BR. High-Throughput Screening of Patient-Derived Cultures Reveals Potential for Precision Medicine in Glioblastoma. Acs Medicinal Chemistry Letters. 6: 948-52. PMID 26288699 DOI: 10.1021/Acsmedchemlett.5B00128 |
0.349 |
|
| 2015 |
Larraufie MH, Yang WS, Jiang E, Thomas AG, Slusher BS, Stockwell BR. Incorporation of metabolically stable ketones into a small molecule probe to increase potency and water solubility. Bioorganic & Medicinal Chemistry Letters. 25: 4787-92. PMID 26231156 DOI: 10.1016/J.Bmcl.2015.07.018 |
0.353 |
|
| 2015 |
Woo JH, Shimoni Y, Yang WS, Subramaniam P, Iyer A, Nicoletti P, Rodríguez Martínez M, López G, Mattioli M, Realubit R, Karan C, Stockwell BR, Bansal M, Califano A. Elucidating Compound Mechanism of Action by Network Perturbation Analysis. Cell. 162: 441-51. PMID 26186195 DOI: 10.1016/J.Cell.2015.05.056 |
0.393 |
|
| 2015 |
Hayano M, Yang WS, Corn CK, Pagano NC, Stockwell BR. Loss of cysteinyl-tRNA synthetase (CARS) induces the transsulfuration pathway and inhibits ferroptosis induced by cystine deprivation. Cell Death and Differentiation. PMID 26184909 DOI: 10.1038/Cdd.2015.93 |
0.43 |
|
| 2015 |
Dixon SJ, Winter GE, Musavi LS, Lee ED, Snijder B, Rebsamen M, Superti-Furga G, Stockwell BR. Human Haploid Cell Genetics Reveals Roles for Lipid Metabolism Genes in Nonapoptotic Cell Death. Acs Chemical Biology. PMID 25965523 DOI: 10.1021/Acschembio.5B00245 |
0.445 |
|
| 2015 |
Kaplan A, Gaschler MM, Dunn DE, Colligan R, Brown LM, Palmer AG, Lo DC, Stockwell BR. Small molecule-induced oxidation of protein disulfide isomerase is neuroprotective. Proceedings of the National Academy of Sciences of the United States of America. 112: E2245-52. PMID 25848045 DOI: 10.1073/Pnas.1500439112 |
0.373 |
|
| 2015 |
Galluzzi L, Bravo-San Pedro JM, Vitale I, Aaronson SA, Abrams JM, Adam D, Alnemri ES, Altucci L, Andrews D, Annicchiarico-Petruzzelli M, Baehrecke EH, Bazan NG, Bertrand MJ, Bianchi K, Blagosklonny MV, ... ... Stockwell BR, et al. Essential versus accessory aspects of cell death: recommendations of the NCCD 2015. Cell Death and Differentiation. 22: 58-73. PMID 25236395 DOI: 10.1038/Cdd.2014.137 |
0.432 |
|
| 2014 |
Friedmann Angeli JP, Schneider M, Proneth B, Tyurina YY, Tyurin VA, Hammond VJ, Herbach N, Aichler M, Walch A, Eggenhofer E, Basavarajappa D, RÃ¥dmark O, Kobayashi S, Seibt T, Beck H, ... ... Stockwell BR, et al. Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice. Nature Cell Biology. 16: 1180-91. PMID 25402683 DOI: 10.1038/Ncb3064 |
0.411 |
|
| 2014 |
Linkermann A, Skouta R, Himmerkus N, Mulay SR, Dewitz C, De Zen F, Prokai A, Zuchtriegel G, Krombach F, Welz PS, Weinlich R, Vanden Berghe T, Vandenabeele P, Pasparakis M, Bleich M, ... ... Stockwell BR, et al. Synchronized renal tubular cell death involves ferroptosis. Proceedings of the National Academy of Sciences of the United States of America. 111: 16836-41. PMID 25385600 DOI: 10.1073/Pnas.1415518111 |
0.356 |
|
| 2014 |
Linkermann A, Stockwell BR, Krautwald S, Anders HJ. Regulated cell death and inflammation: an auto-amplification loop causes organ failure. Nature Reviews. Immunology. 14: 759-67. PMID 25324125 DOI: 10.1038/Nri3743 |
0.394 |
|
| 2014 |
Julien O, Kampmann M, Bassik MC, Zorn JA, Venditto VJ, Shimbo K, Agard NJ, Shimada K, Rheingold AL, Stockwell BR, Weissman JS, Wells JA. Unraveling the mechanism of cell death induced by chemical fibrils. Nature Chemical Biology. 10: 969-76. PMID 25262416 DOI: 10.1038/Nchembio.1639 |
0.428 |
|
| 2014 |
Wolpaw AJ, Stockwell BR. Multidimensional profiling in the investigation of small-molecule-induced cell death. Methods in Enzymology. 545: 265-302. PMID 25065894 DOI: 10.1016/B978-0-12-801430-1.00011-1 |
0.801 |
|
| 2014 |
Cantley AM, Welsch M, Ambesi-Impiombato A, Sanchez-Martin M, Kim MY, Bauer A, Ferrando A, Stockwell BR. Small Molecule that Reverses Dexamethasone Resistance in T-cell Acute Lymphoblastic Leukemia (T-ALL). Acs Medicinal Chemistry Letters. 5: 754-9. PMID 25050160 DOI: 10.1021/Ml500044G |
0.341 |
|
| 2014 |
Dixon SJ, Patel DN, Welsch M, Skouta R, Lee ED, Hayano M, Thomas AG, Gleason CE, Tatonetti NP, Slusher BS, Stockwell BR. Pharmacological inhibition of cystine-glutamate exchange induces endoplasmic reticulum stress and ferroptosis. Elife. 3: e02523. PMID 24844246 DOI: 10.7554/Elife.02523 |
0.374 |
|
| 2014 |
Skouta R, Dixon SJ, Wang J, Dunn DE, Orman M, Shimada K, Rosenberg PA, Lo DC, Weinberg JM, Linkermann A, Stockwell BR. Ferrostatins inhibit oxidative lipid damage and cell death in diverse disease models. Journal of the American Chemical Society. 136: 4551-6. PMID 24592866 DOI: 10.1021/Ja411006A |
0.385 |
|
| 2014 |
Yang WS, SriRamaratnam R, Welsch ME, Shimada K, Skouta R, Viswanathan VS, Cheah JH, Clemons PA, Shamji AF, Clish CB, Brown LM, Girotti AW, Cornish VW, Schreiber SL, Stockwell BR. Regulation of ferroptotic cancer cell death by GPX4. Cell. 156: 317-31. PMID 24439385 DOI: 10.1016/J.Cell.2013.12.010 |
0.797 |
|
| 2014 |
Dixon SJ, Stockwell BR. The role of iron and reactive oxygen species in cell death. Nature Chemical Biology. 10: 9-17. PMID 24346035 DOI: 10.1038/Nchembio.1416 |
0.339 |
|
| 2013 |
Basu A, Bodycombe NE, Cheah JH, Price EV, Liu K, Schaefer GI, Ebright RY, Stewart ML, Ito D, Wang S, Bracha AL, Liefeld T, Wawer M, Gilbert JC, Wilson AJ, ... ... Stockwell BR, et al. An interactive resource to identify cancer genetic and lineage dependencies targeted by small molecules. Cell. 154: 1151-61. PMID 23993102 DOI: 10.1016/J.Cell.2013.08.003 |
0.776 |
|
| 2013 |
Varma H, Gangadhar NM, Letso RR, Wolpaw AJ, Sriramaratnam R, Stockwell BR. Identification of a small molecule that induces ATG5-and-cathepsin-l-dependent cell death and modulates polyglutamine toxicity. Experimental Cell Research. 319: 1759-73. PMID 23588206 DOI: 10.1016/J.Yexcr.2013.03.019 |
0.803 |
|
| 2013 |
Letso RR, Bauer AJ, Lunn MR, Yang WS, Stockwell BR. Small molecule screen reveals regulation of survival motor neuron protein abundance by Ras proteins. Acs Chemical Biology. 8: 914-22. PMID 23496866 DOI: 10.1021/Cb300374H |
0.366 |
|
| 2012 |
Kaplan A, Stockwell BR. Therapeutic approaches to preventing cell death in Huntington disease. Progress in Neurobiology. 99: 262-80. PMID 22967354 DOI: 10.1016/J.Pneurobio.2012.08.004 |
0.445 |
|
| 2012 |
Skouta R, Hayano M, Shimada K, Stockwell BR. Design and synthesis of Pictet-Spengler condensation products that exhibit oncogenic-RAS synthetic lethality and induce non-apoptotic cell death. Bioorganic & Medicinal Chemistry Letters. 22: 5707-13. PMID 22832321 DOI: 10.1016/J.Bmcl.2012.06.077 |
0.402 |
|
| 2012 |
Dixon SJ, Lemberg KM, Lamprecht MR, Skouta R, Zaitsev EM, Gleason CE, Patel DN, Bauer AJ, Cantley AM, Yang WS, Morrison B, Stockwell BR. Ferroptosis: an iron-dependent form of nonapoptotic cell death. Cell. 149: 1060-72. PMID 22632970 DOI: 10.1016/J.Cell.2012.03.042 |
0.782 |
|
| 2012 |
Weïwer M, Bittker JA, Lewis TA, Shimada K, Yang WS, MacPherson L, Dandapani S, Palmer M, Stockwell BR, Schreiber SL, Munoz B. Development of small-molecule probes that selectively kill cells induced to express mutant RAS. Bioorganic & Medicinal Chemistry Letters. 22: 1822-6. PMID 22297109 DOI: 10.1016/J.Bmcl.2011.09.047 |
0.583 |
|
| 2012 |
Yang WS, Shimada K, Delva D, Patel M, Ode E, Skouta R, Stockwell BR. Identification of Simple Compounds with Microtubule-Binding Activity That Inhibit Cancer Cell Growth with High Potency. Acs Medicinal Chemistry Letters. 3: 35-38. PMID 22247791 DOI: 10.1021/Ml200195S |
0.363 |
|
| 2012 |
Yang W, Welsch M, Shimada K, Clish C, SriRamaratnam R, Stockwell B. 506 RAS-synthetic-lethal Compounds Induce Lipoxygenase-dependent Cell Death European Journal of Cancer. 48: 156. DOI: 10.1016/S0959-8049(12)72303-1 |
0.375 |
|
| 2011 |
Herman AG, Hayano M, Poyurovsky MV, Shimada K, Skouta R, Prives C, Stockwell BR. Discovery of Mdm2-MdmX E3 ligase inhibitors using a cell-based ubiquitination assay. Cancer Discovery. 1: 312-25. PMID 22586610 DOI: 10.1158/2159-8290.Cd-11-0104 |
0.395 |
|
| 2011 |
Wolpaw AJ, Shimada K, Skouta R, Welsch ME, Akavia UD, Pe'er D, Shaik F, Bulinski JC, Stockwell BR. Modulatory profiling identifies mechanisms of small molecule-induced cell death. Proceedings of the National Academy of Sciences of the United States of America. 108: E771-80. PMID 21896738 DOI: 10.1073/Pnas.1106149108 |
0.793 |
|
| 2011 |
Bauer AJ, Gieschler S, Lemberg KM, McDermott AE, Stockwell BR. Functional model of metabolite gating by human voltage-dependent anion channel 2. Biochemistry. 50: 3408-10. PMID 21425834 DOI: 10.1021/Bi2003247 |
0.759 |
|
| 2010 |
Hoffstrom BG, Kaplan A, Letso R, Schmid RS, Turmel GJ, Lo DC, Stockwell BR. Inhibitors of protein disulfide isomerase suppress apoptosis induced by misfolded proteins. Nature Chemical Biology. 6: 900-6. PMID 21079601 DOI: 10.1038/Nchembio.467 |
0.427 |
|
| 2010 |
Varma H, Yamamoto A, Sarantos MR, Hughes RE, Stockwell BR. Mutant huntingtin alters cell fate in response to microtubule depolymerization via the GEF-H1-RhoA-ERK pathway. The Journal of Biological Chemistry. 285: 37445-57. PMID 20858895 DOI: 10.1074/Jbc.M110.125542 |
0.416 |
|
| 2010 |
Schreiber SL, Shamji AF, Clemons PA, Hon C, Koehler AN, Munoz B, Palmer M, Stern AM, Wagner BK, Powers S, Lowe SW, Guo X, Krasnitz A, Sawey ET, ... ... Stockwell BR, et al. Towards patient-based cancer therapeutics. Nature Biotechnology. 28: 904-6. PMID 20829823 DOI: 10.1038/Nbt0910-904 |
0.767 |
|
| 2010 |
Welsch ME, Snyder SA, Stockwell BR. Privileged scaffolds for library design and drug discovery. Current Opinion in Chemical Biology. 14: 347-61. PMID 20303320 DOI: 10.1016/J.Cbpa.2010.02.018 |
0.332 |
|
| 2009 |
Dixon SJ, Stockwell BR. Identifying druggable disease-modifying gene products. Current Opinion in Chemical Biology. 13: 549-55. PMID 19740696 DOI: 10.1016/J.Cbpa.2009.08.003 |
0.395 |
|
| 2008 |
Lehár J, Stockwell BR, Giaever G, Nislow C. Combination chemical genetics. Nature Chemical Biology. 4: 674-81. PMID 18936752 DOI: 10.1038/Nchembio.120 |
0.347 |
|
| 2008 |
Gangadhar NM, Firestein SJ, Stockwell BR. A novel role for jun N-terminal kinase signaling in olfactory sensory neuronal death. Molecular and Cellular Neurosciences. 38: 518-25. PMID 18571430 DOI: 10.1016/J.Mcn.2008.04.013 |
0.355 |
|
| 2008 |
Yang WS, Stockwell BR. Inhibition of casein kinase 1-epsilon induces cancer-cell-selective, PERIOD2-dependent growth arrest. Genome Biology. 9: R92. PMID 18518968 DOI: 10.1186/Gb-2008-9-6-R92 |
0.414 |
|
| 2008 |
Bauer AJ, Stockwell BR. Neurobiological applications of small molecule screening Chemical Reviews. 108: 1774-1786. PMID 18447397 DOI: 10.1021/Cr0782372 |
0.328 |
|
| 2008 |
Yang WS, Stockwell BR. Synthetic lethal screening identifies compounds activating iron-dependent, nonapoptotic cell death in oncogenic-RAS-harboring cancer cells. Chemistry & Biology. 15: 234-45. PMID 18355723 DOI: 10.1016/J.Chembiol.2008.02.010 |
0.419 |
|
| 2008 |
Varma H, Lo DC, Stockwell BR. High throughput screening for neurodegeneration and complex disease phenotypes. Combinatorial Chemistry & High Throughput Screening. 11: 238-48. PMID 18336216 DOI: 10.2174/138620708783877753 |
0.313 |
|
| 2008 |
Antipova AA, Stockwell BR, Golub TR. Gene expression-based screening for inhibitors of PDGFR signaling. Genome Biology. 9: R47. PMID 18312689 DOI: 10.1186/Gb-2008-9-3-R47 |
0.31 |
|
| 2007 |
Varma H, Cheng R, Voisine C, Hart AC, Stockwell BR. Inhibitors of metabolism rescue cell death in Huntington's disease models. Proceedings of the National Academy of Sciences of the United States of America. 104: 14525-30. PMID 17726098 DOI: 10.1073/Pnas.0704482104 |
0.421 |
|
| 2007 |
Yagoda N, von Rechenberg M, Zaganjor E, Bauer AJ, Yang WS, Fridman DJ, Wolpaw AJ, Smukste I, Peltier JM, Boniface JJ, Smith R, Lessnick SL, Sahasrabudhe S, Stockwell BR. RAS-RAF-MEK-dependent oxidative cell death involving voltage-dependent anion channels. Nature. 447: 864-8. PMID 17568748 DOI: 10.1038/Nature05859 |
0.788 |
|
| 2007 |
Lehár J, Zimmermann GR, Krueger AS, Molnar RA, Ledell JT, Heilbut AM, Short GF, Giusti LC, Nolan GP, Magid OA, Lee MS, Borisy AA, Stockwell BR, Keith CT. Chemical combination effects predict connectivity in biological systems. Molecular Systems Biology. 3: 80. PMID 17332758 DOI: 10.1038/Msb4100116 |
0.751 |
|
| 2007 |
Varma H, Voisine C, DeMarco CT, Cattaneo E, Lo DC, Hart AC, Stockwell BR. Selective inhibitors of death in mutant huntingtin cells. Nature Chemical Biology. 3: 99-100. PMID 17195849 DOI: 10.1038/Nchembio852 |
0.447 |
|
| 2007 |
Gangadhar NM, Stockwell BR. Chemical genetic approaches to probing cell death. Current Opinion in Chemical Biology. 11: 83-7. PMID 17174591 DOI: 10.1016/J.Cbpa.2006.11.033 |
0.496 |
|
| 2006 |
Letso RR, Stockwell BR. Chemical biology: renewing embryonic stem cells. Nature. 444: 692-3. PMID 17151647 DOI: 10.1038/444692B |
0.316 |
|
| 2006 |
Herman AG, Stockwell BR. Enzyme annotation with chemical tools. Chemistry & Biology. 13: 1013-4. PMID 17052604 DOI: 10.1016/J.Chembiol.2006.10.002 |
0.338 |
|
| 2006 |
Desai UA, Pallos J, Ma AA, Stockwell BR, Thompson LM, Marsh JL, Diamond MI. Biologically active molecules that reduce polyglutamine aggregation and toxicity. Human Molecular Genetics. 15: 2114-24. PMID 16720620 DOI: 10.1093/Hmg/Ddl135 |
0.366 |
|
| 2006 |
Moffat J, Grueneberg DA, Yang X, Kim SY, Kloepfer AM, Hinkle G, Piqani B, Eisenhaure TM, Luo B, Grenier JK, Carpenter AE, Foo SY, Stewart SA, Stockwell BR, Hacohen N, et al. A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen. Cell. 124: 1283-98. PMID 16564017 DOI: 10.1016/J.Cell.2006.01.040 |
0.36 |
|
| 2006 |
Yen L, Magnier M, Weissleder R, Stockwell BR, Mulligan RC. Identification of inhibitors of ribozyme self-cleavage in mammalian cells via high-throughput screening of chemical libraries. Rna (New York, N.Y.). 12: 797-806. PMID 16556935 DOI: 10.1261/Rna.2300406 |
0.36 |
|
| 2006 |
Smukste I, Bhalala O, Persico M, Stockwell BR. Using small molecules to overcome drug resistance induced by a viral oncogene. Cancer Cell. 9: 133-46. PMID 16473280 DOI: 10.1016/J.Ccr.2006.01.012 |
0.435 |
|
| 2006 |
Stockwell BR. Preventing protein secretion with chemical glue. Nature Chemical Biology. 2: 7-8. PMID 16408080 DOI: 10.1038/Nchembio0106-7 |
0.351 |
|
| 2005 |
Lunn MR, Stockwell BR. Chemical genetics and orphan genetic diseases. Chemistry & Biology. 12: 1063-73. PMID 16242649 DOI: 10.1016/J.Chembiol.2005.09.005 |
0.319 |
|
| 2005 |
Smukste I, Stockwell BR. Advances in chemical genetics. Annual Review of Genomics and Human Genetics. 6: 261-86. PMID 16124862 DOI: 10.1146/Annurev.Genom.6.080604.162136 |
0.333 |
|
| 2005 |
Keith CT, Borisy AA, Stockwell BR. Multicomponent therapeutics for networked systems. Nature Reviews. Drug Discovery. 4: 71-8. PMID 15688074 DOI: 10.1038/Nrd1609 |
0.731 |
|
| 2004 |
Stockwell BR. Exploring biology with small organic molecules. Nature. 432: 846-54. PMID 15602550 DOI: 10.1038/Nature03196 |
0.313 |
|
| 2004 |
Kelley BP, Lunn MR, Root DE, Flaherty SP, Martino AM, Stockwell BR. A flexible data analysis tool for chemical genetic screens. Chemistry & Biology. 11: 1495-503. PMID 15556000 DOI: 10.1016/J.Chembiol.2004.08.026 |
0.304 |
|
| 2004 |
Lunn MR, Root DE, Martino AM, Flaherty SP, Kelley BP, Coovert DD, Burghes AH, Man NT, Morris GE, Zhou J, Androphy EJ, Sumner CJ, Stockwell BR. Indoprofen upregulates the survival motor neuron protein through a cyclooxygenase-independent mechanism. Chemistry & Biology. 11: 1489-93. PMID 15555999 DOI: 10.1016/J.Chembiol.2004.08.024 |
0.318 |
|
| 2004 |
Bailey SN, Sabatini DM, Stockwell BR. Microarrays of small molecules embedded in biodegradable polymers for use in mammalian cell-based screens. Proceedings of the National Academy of Sciences of the United States of America. 101: 16144-9. PMID 15534212 DOI: 10.1073/Pnas.0404425101 |
0.402 |
|
| 2004 |
Stegmaier K, Ross KN, Colavito SA, O'Malley S, Stockwell BR, Golub TR. Gene expression-based high-throughput screening(GE-HTS) and application to leukemia differentiation. Nature Genetics. 36: 257-63. PMID 14770183 DOI: 10.1038/Ng1305 |
0.352 |
|
| 2004 |
Stockwell BR. The biological magic behind the bullets. Nature Biotechnology. 22: 37-8. PMID 14704700 DOI: 10.1038/Nbt0104-37 |
0.321 |
|
| 2003 |
Smukste I, Stockwell BR. Restoring functions of tumor suppressors with small molecules. Cancer Cell. 4: 419-20. PMID 14706331 DOI: 10.1016/S1535-6108(03)00307-6 |
0.368 |
|
| 2003 |
Root DE, Flaherty SP, Kelley BP, Stockwell BR. Biological mechanism profiling using an annotated compound library. Chemistry & Biology. 10: 881-92. PMID 14522058 DOI: 10.1016/J.Chembiol.2003.08.009 |
0.394 |
|
| 2003 |
Borisy AA, Elliott PJ, Hurst NW, Lee MS, Lehar J, Price ER, Serbedzija G, Zimmermann GR, Foley MA, Stockwell BR, Keith CT. Systematic discovery of multicomponent therapeutics. Proceedings of the National Academy of Sciences of the United States of America. 100: 7977-82. PMID 12799470 DOI: 10.1073/Pnas.1337088100 |
0.764 |
|
| 2003 |
Dolma S, Lessnick SL, Hahn WC, Stockwell BR. Identification of genotype-selective antitumor agents using synthetic lethal chemical screening in engineered human tumor cells. Cancer Cell. 3: 285-96. PMID 12676586 DOI: 10.1016/S1535-6108(03)00050-3 |
0.4 |
|
| 2002 |
Stockwell BR. Chemical genetic screening approaches to neurobiology. Neuron. 36: 559-62. PMID 12441046 DOI: 10.1016/S0896-6273(02)01056-5 |
0.401 |
|
| 2002 |
Blanchard BJ, Stockwell BR, Ingram VM. Eliminating membrane depolarization caused by the Alzheimer peptide Abeta(1-42, aggr.). Biochemical and Biophysical Research Communications. 293: 1204-8. PMID 12054503 DOI: 10.1016/S0006-291X(02)00290-5 |
0.32 |
|
| 2000 |
Stockwell BR. Chemical genetics: ligand-based discovery of gene function. Nature Reviews. Genetics. 1: 116-25. PMID 11253651 DOI: 10.1038/35038557 |
0.33 |
|
| 2000 |
Stockwell BR. Frontiers in chemical genetics. Trends in Biotechnology. 18: 449-55. PMID 11058785 DOI: 10.1016/S0167-7799(00)01499-2 |
0.371 |
|
| 2000 |
Walters MA, Tan DS, Foley MA, Stockwell BR, Shair MD, Schreiber SL. Synthesis and preliminary evaluation of a library of polycyclic small molecules for use in chemical genetic assays Chemtracts. 13: 268-275. DOI: 10.1021/Ja992144N |
0.759 |
|
| 2000 |
Walters MA, Tan DS, Foley MA, Stockwell BR, Shair MD, Schreiber SL. Synthesis and preliminary evaluation of a library of polycyclic small molecules for use in chemical genetic assays Chemtracts. 13: 268-275. |
0.612 |
|
| 1999 |
Stockwell BR, Haggarty SJ, Schreiber SL. High-throughput screening of small molecules in miniaturized mammalian cell-based assays involving post-translational modifications. Chemistry & Biology. 6: 71-83. PMID 10021420 DOI: 10.1016/S1074-5521(99)80004-0 |
0.678 |
|
| 1999 |
Stockwell BR, Hardwick JS, Tong JK, Schreiber SL. Chemical genetic and genomic approaches reveal a role for copper in specific gene activation [19] Journal of the American Chemical Society. 121: 10662-10663. DOI: 10.1021/Ja9921221 |
0.722 |
|
| 1998 |
Stockwell BR, Schreiber SL. TGF-beta-signaling with small molecule FKBP12 antagonists that bind myristoylated FKBP12-TGF-beta type I receptor fusion proteins. Chemistry & Biology. 5: 385-95. PMID 9662508 DOI: 10.1016/S1074-5521(98)90072-2 |
0.414 |
|
| 1998 |
Stockwell BR, Schreiber SL. Probing the role of homomeric and heteromeric receptor interactions in TGF-beta signaling using small molecule dimerizers. Current Biology : Cb. 8: 761-70. PMID 9651680 DOI: 10.1016/S0960-9822(98)70299-4 |
0.401 |
|
| 1998 |
Muzio M, Stockwell BR, Stennicke HR, Salvesen GS, Dixit VM. An induced proximity model for caspase-8 activation. The Journal of Biological Chemistry. 273: 2926-30. PMID 9446604 DOI: 10.1074/Jbc.273.5.2926 |
0.344 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 2020 |
Werth EG, Rajbhandari P, Stockwell BR, Brown LM. Time Course of Changes in Sorafenib-Treated Hepatocellular Carcinoma (HCC) Cells Suggests Involvement of Phospho-Regulated Signaling in Ferroptosis Induction. Proteomics. e2000006. PMID 32336023 DOI: 10.1002/Pmic.202000006 |
0.3 |
|
| 2011 |
Kosuri P, Kaplan A, Inglés-Prieto Á, Badilla CL, Stockwell BR, Sánchez-Ruiz JM, Holmgren A, Fernández JM. Unraveling the Mechanisms of Oxidative Folding using Single Molecule Force Spectroscopy Biophysical Journal. 100: 480a. DOI: 10.1016/J.Bpj.2010.12.2812 |
0.298 |
|
| 2019 |
Stockwell BR, Jiang X. A Physiological Function for Ferroptosis in Tumor Suppression by the Immune System. Cell Metabolism. 30: 14-15. PMID 31269423 DOI: 10.1016/J.Cmet.2019.06.012 |
0.297 |
|
| 2023 |
Maldonado AC, Haughan MA, Khin M, Ekiert J, Zhang Z, Lantvit D, Al Subeh ZY, Pierre HC, Salkovski M, Hirschhorn T, Gao Y, Pearce CJ, Stockwell BR, Aldrich LN, Oberlies NH, et al. Probing the Cytotoxic Signaling Induced by Eupenifeldin in Ovarian Cancer Models. Journal of Natural Products. PMID 37643353 DOI: 10.1021/acs.jnatprod.3c00186 |
0.297 |
|
| 2007 |
Voisine C, Varma H, Walker N, Bates EA, Stockwell BR, Hart AC. Identification of potential therapeutic drugs for huntington's disease using Caenorhabditis elegans. Plos One. 2: e504. PMID 17551584 DOI: 10.1371/Journal.Pone.0000504 |
0.294 |
|
| 2019 |
Wu J, Minikes AM, Gao M, Bian H, Li Y, Stockwell BR, Chen ZN, Jiang X. Publisher Correction: Intercellular interaction dictates cancer cell ferroptosis via NF2-YAP signalling. Nature. PMID 31371811 DOI: 10.1038/S41586-019-1480-0 |
0.294 |
|
| 2017 |
Linkermann A, Stockwell BR, Vanden Berghe T. Heavy Metal Suicide. American Journal of Physiology. Renal Physiology. ajprenal.00273.2017. PMID 28566503 DOI: 10.1152/Ajprenal.00273.2017 |
0.292 |
|
| 2018 |
Conrad M, Kagan VE, Bayir H, Pagnussat GC, Head B, Traber MG, Stockwell BR. Regulation of lipid peroxidation and ferroptosis in diverse species. Genes & Development. 32: 602-619. PMID 29802123 DOI: 10.1101/Gad.314674.118 |
0.289 |
|
| 2023 |
Vitale I, Pietrocola F, Guilbaud E, Aaronson SA, Abrams JM, Adam D, Agostini M, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Aqeilan RI, Arama E, Baehrecke EH, ... ... Stockwell BR, et al. Apoptotic cell death in disease-Current understanding of the NCCD 2023. Cell Death and Differentiation. PMID 37100955 DOI: 10.1038/s41418-023-01153-w |
0.287 |
|
| 2022 |
Stockwell BR. Ferroptosis turns 10: Emerging mechanisms, physiological functions, and therapeutic applications. Cell. 185: 2401-2421. PMID 35803244 DOI: 10.1016/j.cell.2022.06.003 |
0.281 |
|
| 2018 |
Wang C, Aleksandrov AA, Yang Z, Forouhar F, Proctor EA, Kota P, An J, Kaplan A, Khazanov N, Boël G, Stockwell BR, Senderowitz H, Dokholyan NV, Riordan JR, Brouillette CG, et al. Ligand binding to a remote site thermodynamically corrects the F508del mutation in the human cystic fibrosis transmembrane conductance regulator. The Journal of Biological Chemistry. PMID 29903914 DOI: 10.1074/Jbc.Ra117.000819 |
0.281 |
|
| 2003 |
Kelley BP, Sharan R, Karp RM, Sittler T, Root DE, Stockwell BR, Ideker T. Conserved pathways within bacteria and yeast as revealed by global protein network alignment. Proceedings of the National Academy of Sciences of the United States of America. 100: 11394-9. PMID 14504397 DOI: 10.1073/Pnas.1534710100 |
0.281 |
|
| 2018 |
Zhang Y, Larraufie MH, Musavi L, Akkiraju H, Brown LM, Stockwell BR. Design of small molecules that compete with nucleotide binding to an engineered oncogenic KRAS allele. Biochemistry. PMID 29313669 DOI: 10.1021/Acs.Biochem.7B01113 |
0.278 |
|
| 2019 |
Dixon SJ, Stockwell BR. The Hallmarks of Ferroptosis Annual Review of Cancer Biology. 3: 35-54. DOI: 10.1146/annurev-cancerbio-030518-055844 |
0.278 |
|
| 2023 |
Li J, Liu J, Zhou Z, Wu R, Chen X, Yu C, Stockwell B, Kroemer G, Kang R, Tang D. Tumor-specific GPX4 degradation enhances ferroptosis-initiated antitumor immune response in mouse models of pancreatic cancer. Science Translational Medicine. 15: eadg3049. PMID 37910602 DOI: 10.1126/scitranslmed.adg3049 |
0.274 |
|
| 2010 |
Dixon SJ, Stockwell BR. Drug discovery: engineering drug combinations. Nature Chemical Biology. 6: 318-9. PMID 20404820 DOI: 10.1038/Nchembio.353 |
0.272 |
|
| 2021 |
Jiang X, Stockwell BR, Conrad M. Ferroptosis: mechanisms, biology and role in disease. Nature Reviews. Molecular Cell Biology. PMID 33495651 DOI: 10.1038/s41580-020-00324-8 |
0.271 |
|
| 2023 |
Ferrada L, Barahona MJ, Vera M, Stockwell BR, Nualart F. Dehydroascorbic acid sensitizes cancer cells to system x inhibition-induced ferroptosis by promoting lipid droplet peroxidation. Cell Death & Disease. 14: 637. PMID 37752118 DOI: 10.1038/s41419-023-06153-9 |
0.267 |
|
| 2023 |
Anandhan A, Dodson M, Shakya A, Chen J, Liu P, Wei Y, Tan H, Wang Q, Jiang Z, Yang K, Garcia JG, Chambers SK, Chapman E, Ooi A, Yang-Hartwich Y, ... Stockwell BR, et al. NRF2 controls iron homeostasis and ferroptosis through HERC2 and VAMP8. Science Advances. 9: eade9585. PMID 36724221 DOI: 10.1126/sciadv.ade9585 |
0.265 |
|
| 2004 |
Kelley BP, Yuan B, Lewitter F, Sharan R, Stockwell BR, Ideker T. PathBLAST: a tool for alignment of protein interaction networks. Nucleic Acids Research. 32: W83-8. PMID 15215356 DOI: 10.1093/Nar/Gkh411 |
0.264 |
|
| 2020 |
Hadian K, Stockwell BR. SnapShot: Ferroptosis. Cell. 181: 1188-1188.e1. PMID 32470402 DOI: 10.1016/j.cell.2020.04.039 |
0.259 |
|
| 2020 |
Resnick SJ, Iketani S, Hong SJ, Zask A, Liu H, Kim S, Melore S, Nair MS, Huang Y, Tay NES, Rovis T, Yang HW, Stockwell BR, Ho DD, Chavez A. A simplified cell-based assay to identify coronavirus 3CL protease inhibitors. Biorxiv : the Preprint Server For Biology. PMID 32869020 DOI: 10.1101/2020.08.29.272864 |
0.253 |
|
| 2021 |
Liu H, Forouhar F, Seibt T, Saneto R, Wigby K, Friedman J, Xia X, Shchepinov MS, Ramesh SK, Conrad M, Stockwell BR. Characterization of a patient-derived variant of GPX4 for precision therapy. Nature Chemical Biology. PMID 34931062 DOI: 10.1038/s41589-021-00915-2 |
0.253 |
|
| 2022 |
Liu H, Iketani S, Zask A, Khanizeman N, Bednarova E, Forouhar F, Fowler B, Hong SJ, Mohri H, Nair MS, Huang Y, Tay NES, Lee S, Karan C, Resnick SJ, ... ... Stockwell BR, et al. Development of optimized drug-like small molecule inhibitors of the SARS-CoV-2 3CL protease for treatment of COVID-19. Nature Communications. 13: 1891. PMID 35393402 DOI: 10.1038/s41467-022-29413-2 |
0.252 |
|
| 2004 |
Stegmaier K, Ross KN, Colavito SA, O'Malley S, Stockwell BR, Golub TR. Erratum: Corrigendum: Gene expression–based high-throughput screening (GE-HTS) and application to leukemia differentiation Nature Genetics. 36: 427-427. DOI: 10.1038/Ng0404-427B |
0.251 |
|
| 2023 |
Banu MA, Dovas A, Argenziano MG, Zhao W, Grajal HC, Higgins DMO, Sperring CP, Pereira B, Ye LF, Mahajan A, Humala N, Furnari JL, Upadhyayula PS, Zandkarimi F, Nguyen TTT, ... ... Stockwell BR, et al. A cell state specific metabolic vulnerability to GPX4-dependent ferroptosis in glioblastoma. Biorxiv : the Preprint Server For Biology. PMID 36865302 DOI: 10.1101/2023.02.22.529581 |
0.249 |
|
| 2023 |
Song S, Su Z, Kon N, Chu B, Li H, Jiang X, Luo J, Stockwell BR, Gu W. ALOX5-mediated ferroptosis acts as a distinct cell death pathway upon oxidative stress in Huntington's disease. Genes & Development. 37: 204-217. PMID 36921996 DOI: 10.1101/gad.350211.122 |
0.245 |
|
| 2014 |
Dixon SJ, Patel DN, Welsch M, Skouta R, Lee ED, Hayano M, Thomas AG, Gleason CE, Tatonetti NP, Slusher BS, Stockwell BR. Author response: Pharmacological inhibition of cystine–glutamate exchange induces endoplasmic reticulum stress and ferroptosis Elife. DOI: 10.7554/Elife.02523.018 |
0.245 |
|
| 2012 |
Kosuri P, Alegre-Cebollada J, Feng J, Kaplan A, Inglés-Prieto A, Badilla CL, Stockwell BR, Sanchez-Ruiz JM, Holmgren A, Fernández JM. Protein folding drives disulfide formation. Cell. 151: 794-806. PMID 23141538 DOI: 10.1016/J.Cell.2012.09.036 |
0.245 |
|
| 2021 |
Resnick SJ, Iketani S, Hong SJ, Zask A, Liu H, Kim S, Melore S, Lin FY, Nair MS, Huang Y, Lee S, Tay NES, Rovis T, Yang HW, Xing L, ... Stockwell BR, et al. Inhibitors of coronavirus 3CL proteases protect cells from protease-mediated cytotoxicity. Journal of Virology. PMID 33910954 DOI: 10.1128/JVI.02374-20 |
0.244 |
|
| 2003 |
Root DE, Kelley BP, Stockwell BR. Detecting spatial patterns in biological array experiments. Journal of Biomolecular Screening. 8: 393-8. PMID 14567791 DOI: 10.1177/1087057103254282 |
0.242 |
|
| 2016 |
Freyer JL, Brucks SD, Gobieski GS, Russell ST, Yozwiak CE, Sun M, Chen Z, Jiang Y, Bandar JS, Stockwell BR, Lambert TH, Campos LM. Clickable Poly(ionic liquids): A Materials Platform for Transfection. Angewandte Chemie (International Ed. in English). PMID 27578602 DOI: 10.1002/Anie.201605214 |
0.24 |
|
| 2022 |
Aldrich LN, Burdette JE, Carcache de Blanco E, Coss CC, Eustaquio AS, Fuchs JR, Kinghorn AD, MacFarlane A, Mize BK, Oberlies NH, Orjala J, Pearce CJ, Phelps MA, Rakotondraibe LH, Ren Y, ... ... Stockwell BR, et al. Discovery of Anticancer Agents of Diverse Natural Origin. Journal of Natural Products. PMID 35213158 DOI: 10.1021/acs.jnatprod.2c00036 |
0.239 |
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| 2009 |
Yen L, Stockwell BR, Mulligan RC. A mammalian cell-based assay for screening inhibitors of RNA cleavage. Methods in Molecular Biology (Clifton, N.J.). 540: 335-47. PMID 19381571 DOI: 10.1007/978-1-59745-558-9_24 |
0.239 |
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| 2023 |
Upadhyayula PS, Higgins DM, Mela A, Banu M, Dovas A, Zandkarimi F, Patel P, Mahajan A, Humala N, Nguyen TTT, Chaudhary KR, Liao L, Argenziano M, Sudhakar T, Sperring CP, ... ... Stockwell BR, et al. Dietary restriction of cysteine and methionine sensitizes gliomas to ferroptosis and induces alterations in energetic metabolism. Nature Communications. 14: 1187. PMID 36864031 DOI: 10.1038/s41467-023-36630-w |
0.238 |
|
| 2004 |
Ingram VM, Blanchard BJ, Chen A, Kelly C, Stafford KA, Stockwell B. P1-191 Blocking the initial molecular mechanism of Alzheimer's disease Neurobiology of Aging. 25: S150. DOI: 10.1016/S0197-4580(04)80504-9 |
0.236 |
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| 2022 |
Liu H, Forouhar F, Lin AJ, Wang Q, Polychronidou V, Soni RK, Xia X, Stockwell BR. Small-molecule allosteric inhibitors of GPX4. Cell Chemical Biology. PMID 36423641 DOI: 10.1016/j.chembiol.2022.11.003 |
0.234 |
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| 2024 |
Dai E, Chen X, Linkermann A, Jiang X, Kang R, Kagan VE, Bayir H, Yang WS, Garcia-Saez AJ, Ioannou MS, Janowitz T, Ran Q, Gu W, Gan B, Krysko DV, ... ... Stockwell BR, et al. A guideline on the molecular ecosystem regulating ferroptosis. Nature Cell Biology. PMID 38424270 DOI: 10.1038/s41556-024-01360-8 |
0.229 |
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| 1997 |
Morgan B, Stockwell BR, Dodds DR, Andrews DR, Sudhakar AR, Nielsen CM, Mergelsberg I, Zumbach A. Chemoenzymatic approaches to SCH 56592, a new azole antifungal Jaocs, Journal of the American Oil Chemists' Society. 74: 1361-1370. DOI: 10.1007/S11746-997-0238-2 |
0.226 |
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| 2021 |
Chen D, Chu B, Yang X, Liu Z, Jin Y, Kon N, Rabadan R, Jiang X, Stockwell BR, Gu W. iPLA2β-mediated lipid detoxification controls p53-driven ferroptosis independent of GPX4. Nature Communications. 12: 3644. PMID 34131139 DOI: 10.1038/s41467-021-23902-6 |
0.226 |
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| 2024 |
Liu X, Chen Z, Yan Y, Zandkarimi F, Nie L, Li Q, Horbath A, Olszewski K, Kondiparthi L, Mao C, Lee H, Zhuang L, Poyurovsky M, Stockwell BR, Chen J, et al. Proteomic analysis of ferroptosis pathways reveals a role of CEPT1 in suppressing ferroptosis. Protein & Cell. PMID 38430542 DOI: 10.1093/procel/pwae004 |
0.217 |
|
| 2022 |
Jin J, Schorpp K, Samaga D, Unger K, Hadian K, Stockwell BR. Machine Learning Classifies Ferroptosis and Apoptosis Cell Death Modalities with TfR1 Immunostaining. Acs Chemical Biology. 17: 654-660. PMID 35230809 DOI: 10.1021/acschembio.1c00953 |
0.212 |
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| 2021 |
Affo S, Nair A, Brundu F, Ravichandra A, Bhattacharjee S, Matsuda M, Chin L, Filliol A, Wen W, Song X, Decker A, Worley J, Caviglia JM, Yu L, Yin D, ... ... Stockwell BR, et al. Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations. Cancer Cell. PMID 33930309 DOI: 10.1016/j.ccell.2021.03.012 |
0.208 |
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| 2023 |
von Krusenstiern AN, Robson RN, Qian N, Qiu B, Hu F, Reznik E, Smith N, Zandkarimi F, Estes VM, Dupont M, Hirschhorn T, Shchepinov MS, Min W, Woerpel KA, Stockwell BR. Identification of essential sites of lipid peroxidation in ferroptosis. Nature Chemical Biology. PMID 36747055 DOI: 10.1038/s41589-022-01249-3 |
0.205 |
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| 2023 |
Liang D, Feng Y, Zandkarimi F, Wang H, Zhang Z, Kim J, Cai Y, Gu W, Stockwell BR, Jiang X. Ferroptosis surveillance independent of GPX4 and differentially regulated by sex hormones. Cell. PMID 37267948 DOI: 10.1016/j.cell.2023.05.003 |
0.204 |
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| 2011 |
Stockwell B. Outsmarting Cancer. A biologist talks about what makes disease-causing proteins so difficult to target with drugs. Scientific American. 305: 20. PMID 22106796 |
0.203 |
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| 2012 |
Kanning KC, Li H, Nikulina E, Hou J, Yang WS, Kaplan A, Bermingham JR, Lamas NJ, Amoroso MW, Wichterle H, Filbin MT, Stockwell B, Henderson CE. Making motor axons grow International Journal of Developmental Neuroscience. 30: 613-614. DOI: 10.1016/J.Ijdevneu.2012.10.106 |
0.2 |
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| 2024 |
Qiu B, Zandkarimi F, Bezjian CT, Reznik E, Soni RK, Gu W, Jiang X, Stockwell BR. Phospholipids with two polyunsaturated fatty acyl tails promote ferroptosis. Cell. PMID 38366593 DOI: 10.1016/j.cell.2024.01.030 |
0.199 |
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| 2020 |
Anthonymuthu TS, Tyurina YY, Sun WY, Mikulska-Ruminska K, Shrivastava IH, Tyurin VA, Cinemre FB, Dar HH, VanDemark AP, Holman TR, Sadovsky Y, Stockwell BR, He RR, Bahar I, Bayır H, et al. Resolving the paradox of ferroptotic cell death: Ferrostatin-1 binds to 15LOX/PEBP1 complex, suppresses generation of peroxidized ETE-PE, and protects against ferroptosis. Redox Biology. 38: 101744. PMID 33126055 DOI: 10.1016/j.redox.2020.101744 |
0.197 |
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| 2017 |
Stockwell BR, Stockwell MS, Jiang E. Group Problem Solving in Class Improves Undergraduate Learning. Acs Central Science. 3: 614-620. PMID 28691073 DOI: 10.1021/Acscentsci.7B00133 |
0.19 |
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| 2023 |
Michels J, Venkatesh D, Liu C, Budhu S, Zhong H, George MM, Thach D, Yao ZK, Ouerfelli O, Liu H, Stockwell BR, Campesato LF, Zamarin D, Zappasodi R, Wolchok JD, et al. APR-246 increases tumor antigenicity independent of p53. Life Science Alliance. 7. PMID 37891002 DOI: 10.26508/lsa.202301999 |
0.188 |
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| 2023 |
Smith N, Reznik E, Bisikirska B, Polychronidou V, Wang Q, Zask A, Forouhar F, Califano A, Stockwell BR. Kinases Controlling Stability of the Oncogenic MYCN Protein. Acs Medicinal Chemistry Letters. 14: 1664-1672. PMID 38116412 DOI: 10.1021/acsmedchemlett.3c00274 |
0.187 |
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| 2023 |
Yang X, Wang Z, Zandkarimi F, Liu Y, Duan S, Li Z, Kon N, Zhang Z, Jiang X, Stockwell BR, Gu W. Regulation of VKORC1L1 is critical for p53-mediated tumor suppression through vitamin K metabolism. Cell Metabolism. PMID 37467745 DOI: 10.1016/j.cmet.2023.06.014 |
0.186 |
|
| 2002 |
Root DE, Kelley BP, Stockwell BR. Global analysis of large-scale chemical and biological experiments. Current Opinion in Drug Discovery & Development. 5: 355-60. PMID 12058610 |
0.186 |
|
| 2015 |
Stockwell BR, Stockwell MS, Cennamo M, Jiang E. Blended Learning Improves Science Education. Cell. 162: 933-6. PMID 26317458 DOI: 10.1016/J.Cell.2015.08.009 |
0.184 |
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| 2016 |
Klionsky DJ, Abdelmohsen K, Abe A, Abedin J, Abeliovich H, Arozena AA, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Stockwell BR, et al. Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356 Autophagy. 12: 443-443. PMID 26902590 DOI: 10.1080/15548627.2016.1147886 |
0.184 |
|
| 2015 |
Bertozzi CR, Stockwell BR, Kubicek S, Dickinson BC, Chang CJ, Schultz C, Silver PA, Gestwicki JE, Chiosis G, Chattopadhyay A, Butcher RA, Park SB, Shoichet BK, Flitsch SL, Zhang J, et al. Voices of chemical biology Nature Chemical Biology. 11: 378-379. PMID 25978987 DOI: 10.1038/Nchembio.1820 |
0.183 |
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| 2022 |
Prives C, Suzuki S, Venkatesh D, Kanda H, Nakayama A, Hosokawa H, Lee E, Miki T, Stockwell BR, Yokote K, Tanaka T. GLS2 is a tumor suppressor and a regulator of ferroptosis in hepatocellular carcinoma. Cancer Research. PMID 35895807 DOI: 10.1158/0008-5472.CAN-21-3914 |
0.182 |
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| 2022 |
Reglero C, Dieck CL, Zask A, Forouhar F, Laurent AP, Lin WW, Albero R, Miller HI, Ma C, Gastier-Foster JM, Loh ML, Tong L, Stockwell BR, Palomero T, Ferrando AA. Pharmacological inhibition of NT5C2 reverses genetic and non-genetic drivers of 6-MP resistance in acute lymphoblastic leukemia. Cancer Discovery. PMID 35984649 DOI: 10.1158/2159-8290.CD-22-0010 |
0.178 |
|
| 2021 |
Iketani S, Forouhar F, Liu H, Hong SJ, Lin FY, Nair MS, Zask A, Huang Y, Xing L, Stockwell BR, Chavez A, Ho DD. Lead compounds for the development of SARS-CoV-2 3CL protease inhibitors. Nature Communications. 12: 2016. PMID 33795671 DOI: 10.1038/s41467-021-22362-2 |
0.178 |
|
| 2020 |
Iketani S, Forouhar F, Liu H, Hong SJ, Lin FY, Nair MS, Zask A, Huang Y, Xing L, Stockwell BR, Chavez A, Ho DD. Lead compounds for the development of SARS-CoV-2 3CL protease inhibitors. Biorxiv : the Preprint Server For Biology. PMID 32793898 DOI: 10.1101/2020.08.03.235291 |
0.178 |
|
| 2020 |
Venkatesh D, Stockwell BR, Prives C. p21 can be a barrier to ferroptosis independent of p53. Aging. 12: 17800-17814. PMID 32979260 DOI: 10.18632/aging.103961 |
0.173 |
|
| 2021 |
Iketani S, Forouhar F, Liu H, Hong SJ, Lin FY, Nair MS, Zask A, Huang Y, Xing L, Stockwell BR, Chavez A, Ho DD. Author Correction: Lead compounds for the development of SARS-CoV-2 3CL protease inhibitors. Nature Communications. 12: 2708. PMID 33953192 DOI: 10.1038/s41467-021-23082-3 |
0.161 |
|
| 2015 |
Kaplan A, Stockwell BR. Structural elucidation of a small molecule inhibitor of protein disulfide isomerase Acs Medicinal Chemistry Letters. 6: 966-971. DOI: 10.1021/acsmedchemlett.5b00014 |
0.161 |
|
| 2024 |
Kordi N, Saydi A, Karami S, Bagherzadeh-Rahmani B, Marzetti E, Jung F, Stockwell BR. Ferroptosis and aerobic training in ageing: A review. Clinical Hemorheology and Microcirculation. PMID 38306027 DOI: 10.3233/CH-232076 |
0.161 |
|
| 2023 |
Lee AJ, Gangi LR, Zandkarimi F, Stockwell BR, Hung CT. Red Blood Cell Exposure Increases Chondrocyte Susceptibility to Oxidative Stress Following Hemarthrosis. Osteoarthritis and Cartilage. PMID 37364817 DOI: 10.1016/j.joca.2023.06.007 |
0.16 |
|
| 2015 |
Hayano M, Yang WS, Corn CK, Pagano NC, Stockwell BR. Loss of cysteinyl-tRNA synthetase (CARS) induces the transsulfuration pathway and inhibits ferroptosis induced by cystine deprivation Cell Death and Differentiation. DOI: 10.1038/cdd.2015.93 |
0.16 |
|
| 2024 |
Tian H, Rajbhandari P, Tarolli J, Decker AM, Neelakantan TV, Angerer T, Zandkarimi F, Remotti H, Frache G, Winograd N, Stockwell BR. Multimodal mass spectrometry imaging identifies cell-type-specific metabolic and lipidomic variation in the mammalian liver. Developmental Cell. PMID 38359832 DOI: 10.1016/j.devcel.2024.01.025 |
0.157 |
|
| 2024 |
Yang X, Wang Z, Samovich SN, Kapralov AA, Amoscato AA, Tyurin VA, Dar HH, Li Z, Duan S, Kon N, Chen D, Tycko B, Zhang Z, Jiang X, Bayir H, ... Stockwell BR, et al. PHLDA2-mediated phosphatidic acid peroxidation triggers a distinct ferroptotic response during tumor suppression. Cell Metabolism. PMID 38309267 DOI: 10.1016/j.cmet.2024.01.006 |
0.156 |
|
| 2024 |
Wang Z, Yang X, Chen D, Liu Y, Li Z, Duan S, Zhang Z, Jiang X, Stockwell BR, Gu W. GAS41 modulates ferroptosis by anchoring NRF2 on chromatin. Nature Communications. 15: 2531. PMID 38514704 DOI: 10.1038/s41467-024-46857-w |
0.145 |
|
| 2021 |
Cheff DM, Muotri AR, Stockwell BR, Schmidt EE, Ran Q, Kartha RV, Johnson SC, Mittal P, Arnér ESJ, Wigby KM, Hall MD, Ramesh SK. Development of therapies for rare genetic disorders of GPX4: roadmap and opportunities. Orphanet Journal of Rare Diseases. 16: 446. PMID 34688299 DOI: 10.1186/s13023-021-02048-0 |
0.143 |
|
| 2015 |
Woo JH, Shimoni Y, Yang WS, Subramaniam P, Iyer A, Nicoletti P, Rodríguez Martínez M, López G, Mattioli M, Realubit R, Karan C, Stockwell BR, Bansal M, Califano A. Elucidating Compound Mechanism of Action by Network Perturbation Analysis Cell. 162: 441-451. DOI: 10.1016/j.cell.2015.05.056 |
0.142 |
|
| 2023 |
Mann J, Reznik E, Santer M, Fongheiser MA, Smith N, Hirschhorn T, Zandkarimi F, Soni RK, Dafré AL, Miranda-Vizuete A, Farina M, Stockwell BR. Ferroptosis inhibition by oleic acid mitigates iron-overload-induced injury. Cell Chemical Biology. PMID 37944523 DOI: 10.1016/j.chembiol.2023.10.012 |
0.142 |
|
| 2022 |
Hirschhorn T, Stockwell BR. Vitamin K: A new guardian against ferroptosis. Molecular Cell. 82: 3760-3762. PMID 36270246 DOI: 10.1016/j.molcel.2022.10.001 |
0.14 |
|
| 2022 |
Wong Fok Lung T, Charytonowicz D, Beaumont KG, Shah SS, Sridhar SH, Gorrie CL, Mu A, Hofstaedter CE, Varisco D, McConville TH, Drikic M, Fowler B, Urso A, Shi W, Fucich D, ... ... Stockwell BR, et al. Klebsiella pneumoniae induces host metabolic stress that promotes tolerance to pulmonary infection. Cell Metabolism. PMID 35413274 DOI: 10.1016/j.cmet.2022.03.009 |
0.14 |
|
| 2015 |
Quartararo CE, Reznik E, DeCarvalho AC, Mikkelsen T, Stockwell BR. High-Throughput Screening of Patient-Derived Cultures Reveals Potential for Precision Medicine in Glioblastoma Acs Medicinal Chemistry Letters. 6: 948-952. DOI: 10.1021/acsmedchemlett.5b00128 |
0.133 |
|
| 2021 |
Affo S, Nair A, Brundu F, Ravichandra A, Bhattacharjee S, Matsuda M, Chin L, Filliol A, Wen W, Song X, Decker A, Worley J, Caviglia JM, Yu L, Yin D, ... ... Stockwell BR, et al. Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations. Cancer Cell. 39: 883. PMID 34129825 DOI: 10.1016/j.ccell.2021.05.010 |
0.127 |
|
| 2023 |
Rajbhandari P, Neelakantan TV, Hosny N, Stockwell BR. Spatial pharmacology using mass spectrometry imaging. Trends in Pharmacological Sciences. 45: 67-80. PMID 38103980 DOI: 10.1016/j.tips.2023.11.003 |
0.124 |
|
| 2022 |
Yan R, Xie E, Li Y, Li J, Zhang Y, Chi X, Hu X, Xu L, Hou T, Stockwell BR, Min J, Zhou Q, Wang F. The structure of erastin-bound xCT-4F2hc complex reveals molecular mechanisms underlying erastin-induced ferroptosis. Cell Research. PMID 35352032 DOI: 10.1038/s41422-022-00642-w |
0.113 |
|
| 2005 |
Stegmaier K, Ross KN, Colavito SA, O'Malley S, Stockwell BR, Golub TR. Erratum: Corrigendum: Gene expression–based high-throughput screening (GE-HTS) and application to leukemia differentiation Nature Genetics. 37: 328-328. DOI: 10.1038/ng0305-328a |
0.096 |
|
| 2023 |
Jain S, Pei L, Spraggins JM, Angelo M, Carson JP, Gehlenborg N, Ginty F, Gonçalves JP, Hagood JS, Hickey JW, Kelleher NL, Laurent LC, Lin S, Lin Y, Liu H, ... ... Stockwell BR, et al. Advances and prospects for the Human BioMolecular Atlas Program (HuBMAP). Nature Cell Biology. PMID 37468756 DOI: 10.1038/s41556-023-01194-w |
0.085 |
|
| 2023 |
Quardokus EM, Saunders DC, McDonough E, Hickey JW, Werlein C, Surrette C, Rajbhandari P, Casals AM, Tian H, Lowery L, Neumann EK, Björklund F, Neelakantan TV, Croteau J, Wiblin AE, ... ... Stockwell BR, et al. Organ Mapping Antibody Panels: a community resource for standardized multiplexed tissue imaging. Nature Methods. PMID 37468619 DOI: 10.1038/s41592-023-01846-7 |
0.074 |
|
| 2021 |
Hadian K, Stockwell BR. A roadmap to creating ferroptosis-based medicines. Nature Chemical Biology. 17: 1113-1116. PMID 34675413 DOI: 10.1038/s41589-021-00853-z |
0.057 |
|
| 2011 |
Stockwell BR. Understanding the role of disturbance in peri-urban agricultural systems and communities: New concepts and principles to guide strategic intervention International Journal of Innovation and Sustainable Development. 5: 389-402. DOI: 10.1504/IJISD.2011.043337 |
0.046 |
|
| 2024 |
Jain S, Pei L, Spraggins JM, Angelo M, Carson JP, Gehlenborg N, Ginty F, Gonçalves JP, Hagood JS, Hickey JW, Kelleher NL, Laurent LC, Lin S, Lin Y, Liu H, ... ... Stockwell BR, et al. Author Correction: Advances and prospects for the Human BioMolecular Atlas Program (HuBMAP). Nature Cell Biology. PMID 38429479 DOI: 10.1038/s41556-024-01384-0 |
0.038 |
|
| 2010 |
Stockwell BR, Tuma RS. The Immortal Life of Henrietta Lacks by Rebecca Skloot; Review of the Book, and an Interview with the Author Oncology Times. 32: 44-48. DOI: 10.1097/01.COT.0000369686.28587.20 |
0.031 |
|
| 2010 |
Stockwell BR. The Immortal Life of Henrietta Lacks, by Rebecca Skloot Nephrology Times. 3: 12-13. DOI: 10.1097/01.NEP.0000370098.85226.1C |
0.031 |
|
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