Year |
Citation |
Score |
2024 |
Beverley KM, Barbera N, Levitan I. Dual pattern of cholesterol-induced decoupling of residue-residue interactions of Kir2.2. Journal of Structural Biology. 216: 108091. PMID 38641256 DOI: 10.1016/j.jsb.2024.108091 |
0.39 |
|
2024 |
Beverley KM, Levitan I. Cholesterol regulation of mechanosensitive ion channels. Frontiers in Cell and Developmental Biology. 12: 1352259. PMID 38333595 DOI: 10.3389/fcell.2024.1352259 |
0.465 |
|
2023 |
Fancher IS, Levitan I. Membrane Cholesterol Interactions with Proteins in Hypercholesterolemia-Induced Endothelial Dysfunction. Current Atherosclerosis Reports. 25: 535-541. PMID 37418067 DOI: 10.1007/s11883-023-01127-w |
0.337 |
|
2022 |
Barbera N, Granados ST, Vanoye CG, Abramova TV, Kulbak D, Ahn SJ, George AL, Akpa BS, Levitan I. Cholesterol-induced suppression of Kir2 channels is mediated by decoupling at the inter-subunit interfaces. Iscience. 25: 104329. PMID 35602957 DOI: 10.1016/j.isci.2022.104329 |
0.431 |
|
2022 |
Rezende L, Couto NFD, Fernandes-Braga W, Epshtein Y, Alvarez-Leite JI, Levitan I, Andrade LO. OxLDL induces membrane structure rearrangement leading to biomechanics alteration and migration deficiency in macrophage. Biochimica Et Biophysica Acta. Biomembranes. 1864: 183951. PMID 35504320 DOI: 10.1016/j.bbamem.2022.183951 |
0.331 |
|
2021 |
Levitan I. Evaluating membrane structure by Laurdan imaging: Disruption of lipid packing by oxidized lipids. Current Topics in Membranes. 88: 235-256. PMID 34862028 DOI: 10.1016/bs.ctm.2021.10.003 |
0.327 |
|
2021 |
Ahn SJ, Fancher IS, Granados ST, Do Couto NF, Hwang CL, Phillips SA, Levitan I. Cholesterol-Induced Suppression of Endothelial Kir Channels Is a Driver of Impairment of Arteriolar Flow-Induced Vasodilation in Humans. Hypertension (Dallas, Tex. : 1979). HYPERTENSIONAHA12117. PMID 34784737 DOI: 10.1161/HYPERTENSIONAHA.121.17672 |
0.373 |
|
2021 |
Ayee MAA, Levitan I. Lipoprotein-Induced Increases in Cholesterol and 7-Ketocholesterol Result in Opposite Molecular-Scale Biophysical Effects on Membrane Structure. Frontiers in Cardiovascular Medicine. 8: 715932. PMID 34336964 DOI: 10.3389/fcvm.2021.715932 |
0.33 |
|
2020 |
Srivastava N, Tauseef M, Amin R, Joshi B, Joshi JC, Kini V, Klomp J, Li W, Knezevic N, Barbera N, Siddiqui S, Obukhov A, Karginov A, Levitan I, Komarova Y, et al. Noncanonical function of long myosin light chain kinase in increasing ER-PM junctions and augmentation of SOCE. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32772419 DOI: 10.1096/Fj.201902462Rr |
0.302 |
|
2020 |
Fancher IS, Le Master E, Ahn SJ, Adamos C, Lee JC, Berdyshev E, Dull RO, Phillips SA, Levitan I. Impairment of Flow-Sensitive Inwardly Rectifying K Channels via Disruption of Glycocalyx Mediates Obesity-Induced Endothelial Dysfunction. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA120314935. PMID 32698687 DOI: 10.1161/Atvbaha.120.314935 |
0.309 |
|
2020 |
Fancher IS, Levitan I. Endothelial inwardly-rectifying K+ channels as a key component of shear stress-induced mechanotransduction Current Topics in Membranes. 85: 59-88. PMID 32402645 DOI: 10.1016/Bs.Ctm.2020.02.002 |
0.434 |
|
2020 |
Bogachkov YY, Chen L, Le Master E, Fancher IS, Zhao Y, Oh MJ, Wary KK, DiPietro LA, Levitan I. LDL induces cholesterol loading, inhibits endothelial proliferation, and angiogenesis in Matrigels: Correlation with impaired angiogenesis during wound healing. American Journal of Physiology. Cell Physiology. PMID 31995410 DOI: 10.1152/Ajpcell.00495.2018 |
0.422 |
|
2020 |
Barbera N, Akpa BS, Levitan I. Molecular Simulations of Kir-Cholesterol Interactions Uncover Cholesterol-Mediated De-Coupling of Functional Domains Important for Gating Biophysical Journal. 118. DOI: 10.1016/J.Bpj.2019.11.3037 |
0.386 |
|
2020 |
Ayee MA, Lam K, Levitan I. Impact of Dyslipidemic Levels of Oxidized Cholesterol on Endothelial Membranes Biophysical Journal. 118. DOI: 10.1016/J.Bpj.2019.11.1131 |
0.429 |
|
2019 |
Gutorov R, Peters M, Katz B, Brandwine T, Barbera NA, Levitan I, Minke B. Modulation of Transient Receptor Potential C Channel Activity by Cholesterol. Frontiers in Pharmacology. 10: 1487. PMID 31920669 DOI: 10.3389/Fphar.2019.01487 |
0.563 |
|
2019 |
Fancher IS, Levitan I. Electrophysiological Recordings of Single-cell Ion Currents Under Well-defined Shear Stress. Journal of Visualized Experiments. PMID 31424433 DOI: 10.3791/59776 |
0.413 |
|
2019 |
Boriushkin E, Fancher IS, Levitan I. Shear-Stress Sensitive Inwardly-Rectifying K+ Channels Regulate Developmental Retinal Angiogenesis by Vessel Regression. Cellular Physiology and Biochemistry. 52: 1569-1583. PMID 31145841 DOI: 10.33594/000000109 |
0.376 |
|
2019 |
Barbera NA, Minke B, Levitan I. Comparative docking analysis of cholesterol analogs to ion channels to discriminate between stereospecific binding vs. stereospecific response. Channels. 13: 136-146. PMID 31033379 DOI: 10.1080/19336950.2019.1606670 |
0.472 |
|
2019 |
Barbera N, Levitan I. Chiral Specificity of Cholesterol Orientation Within Cholesterol Binding Sites in Inwardly Rectifying K+ Channels. Advances in Experimental Medicine and Biology. 1115: 77-95. PMID 30649756 DOI: 10.1007/978-3-030-04278-3_4 |
0.541 |
|
2019 |
Ali M, Mahmoud AM, Le Master E, Levitan I, Phillips SA. Role of Matrix Metalloproteinases and Histone Deacetylase in Oxidative Stress-induced Degradation of the Endothelial Glycocalyx. American Journal of Physiology. Heart and Circulatory Physiology. PMID 30632766 DOI: 10.1152/Ajpheart.00090.2018 |
0.314 |
|
2019 |
Ayee MA, Levitan I. Dyslipidemia Induced Endothelial Stiffening is Accompanied by Increased Membrane Tension Biophysical Journal. 116. DOI: 10.1016/J.Bpj.2018.11.919 |
0.39 |
|
2018 |
Ayee MAA, Levitan I. Membrane Stiffening in Osmotic Swelling: Analysis of Membrane Tension and Elastic Modulus Current Topics in Membranes. 81: 97-123. PMID 30243442 DOI: 10.1016/Bs.Ctm.2018.07.003 |
0.349 |
|
2018 |
Barbera N, Ayee MAA, Akpa BS, Levitan I. Molecular Dynamics Simulations of Kir2.2 Interactions with an Ensemble of Cholesterol Molecules Biophysical Journal. 115: 1264-1280. PMID 30205899 DOI: 10.1016/J.Bpj.2018.07.041 |
0.527 |
|
2018 |
Fancher IS, Ahn SJ, Adamos C, Osborn C, Oh MJ, Fang Y, Reardon CA, Getz GS, Phillips SA, Levitan I. Hypercholesterolemia-Induced Loss of Flow-Induced Vasodilation and Lesion Formation in Apolipoprotein E-Deficient Mice Critically Depend on Inwardly Rectifying KChannels. Journal of the American Heart Association. 7. PMID 29502106 DOI: 10.1161/Jaha.117.007430 |
0.368 |
|
2018 |
Ayee MAA, LeMaster E, Teng T, Lee J, Levitan I. Hypotonic Challenge of Endothelial Cells Increases Membrane Stiffness with No Effect on Tether Force. Biophysical Journal. 114: 929-938. PMID 29490252 DOI: 10.1016/J.Bpj.2017.12.032 |
0.389 |
|
2017 |
Le Master E, Huang RT, Zhang C, Bogachkov Y, Coles C, Shentu TP, Sheng Y, Fancher IS, Ng C, Christoforidis T, Subbaiah PV, Berdyshev E, Qain Z, Eddington DT, Lee J, ... ... Levitan I, et al. Proatherogenic Flow Increases Endothelial Stiffness via Enhanced CD36 (Cluster of Differentiation 36)-Mediated OxLDL (Oxidized Low-Density Lipoprotein) Uptake. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 29025707 DOI: 10.1161/Atvbaha.117.309907 |
0.376 |
|
2017 |
Barbera N, Ayee MAA, Akpa BS, Levitan I. Differential Effects of Sterols on Ion Channels: Stereospecific Binding vs Stereospecific Response. Current Topics in Membranes. 80: 25-50. PMID 28863819 DOI: 10.1016/Bs.Ctm.2017.06.001 |
0.512 |
|
2017 |
Zhang C, Adamos C, Oh MJ, Baruah J, Ayee MAA, Mehta D, Wary KK, Levitan I. OxLDL-induced endothelial proliferation via Rho/ROCK/Akt/p27(kip1) signaling: prevention by cholesterol loading. American Journal of Physiology. Cell Physiology. ajpcell.00249.2016. PMID 28701359 DOI: 10.1152/Ajpcell.00249.2016 |
0.37 |
|
2017 |
Ayee MA, LeMaster E, Shentu TP, Singh DK, Barbera N, Soni D, Tiruppathi C, Subbaiah PV, Berdyshev E, Bronova I, Cho M, Akpa BS, Levitan I. Molecular-Scale Biophysical Modulation of an Endothelial Membrane by Oxidized Phospholipids. Biophysical Journal. 112: 325-338. PMID 28122218 DOI: 10.1016/J.Bpj.2016.12.002 |
0.421 |
|
2016 |
Liu SL, Sheng R, Jung JH, Wang L, Stec E, O'Connor MJ, Song S, Bikkavilli RK, Winn RA, Lee D, Baek K, Ueda K, Levitan I, Kim KP, Cho W. Orthogonal lipid sensors identify transbilayer asymmetry of plasma membrane cholesterol. Nature Chemical Biology. PMID 28024150 DOI: 10.1038/Nchembio.2268 |
0.468 |
|
2016 |
Ahn SJ, Fancher IS, Bian JT, Zhang CX, Schwab S, Gaffin R, Phillips SA, Levitan I. Inwardly-rectifying K(+) channels are major contributors to flow-induced vasodilation in resistance arteries. The Journal of Physiology. PMID 27859264 DOI: 10.1113/Jp273255 |
0.399 |
|
2016 |
Ayee MA, Levitan I. Paradoxical impact of cholesterol on lipid packing and cell stiffness. Frontiers in Bioscience (Landmark Edition). 21: 1245-59. PMID 27100504 DOI: 10.2741/4454 |
0.475 |
|
2016 |
Oh MJ, Zhang C, LeMaster E, Adamos C, Berdyshev E, Bogachkov Y, Kohler EE, Baruah J, Fang Y, Schraufnagel DE, Wary KK, Levitan I. Oxidized-LDL Signals through Rho-GTPase to Induce Endothelial Cell Stiffening and Promote Capillary Formation. Journal of Lipid Research. PMID 26989083 DOI: 10.1194/Jlr.M062539 |
0.377 |
|
2016 |
Levitan I. Impact of hypercholesterolemia on cardiac K+ channels Journal of Clinical and Experimental Cardiology. DOI: 10.4172/2155-9880.C1.035 |
0.53 |
|
2016 |
Ayee MA, LeMaster E, Akpa BS, Levitan I. Endothelial Membrane Modulation by OxLDL: Molecular-Scale Effects of Oxidation Products on Model Membranes Biophysical Journal. 110. DOI: 10.1016/J.Bpj.2015.11.498 |
0.392 |
|
2016 |
Han H, Rosenhouse-Dantsker A, Gnanasambandam R, Sachs F, Levitan I. Cross-Talk between Cholesterol, PIP2 and Caveolin in Regulating Kir2 Channels Biophysical Journal. 110: 608a. DOI: 10.1016/J.Bpj.2015.11.3246 |
0.528 |
|
2016 |
Barbera N, Ayee MA, Akpa BS, Levitan I. Molecular Dynamics Simulations of Kir2.2-Cholesterol Interactions Biophysical Journal. 110. DOI: 10.1016/J.Bpj.2015.11.1038 |
0.513 |
|
2015 |
Bukiya AN, Osborn CV, Kuntamallappanavar G, Toth PT, Baki L, Kowalsky G, Oh MJ, Dopico AM, Levitan I, Rosenhouse-Dantsker A. Cholesterol increases the open probability of cardiac KACh currents. Biochimica Et Biophysica Acta. PMID 26196595 DOI: 10.1016/J.Bbamem.2015.07.007 |
0.554 |
|
2014 |
Rosenhouse-Dantsker A, Epshtein Y, Levitan I. Interplay Between Lipid Modulators of Kir2 Channels: Cholesterol and PIP2. Computational and Structural Biotechnology Journal. 11: 131-7. PMID 25408847 DOI: 10.1016/J.Csbj.2014.09.007 |
0.554 |
|
2014 |
Han H, Rosenhouse-Dantsker A, Gnanasambandam R, Epshtein Y, Chen Z, Sachs F, Minshall RD, Levitan I. Silencing of Kir2 channels by caveolin-1: cross-talk with cholesterol. The Journal of Physiology. 592: 4025-38. PMID 25038242 DOI: 10.1113/Jphysiol.2014.273177 |
0.537 |
|
2014 |
Levitan I, Singh DK, Rosenhouse-Dantsker A. Cholesterol binding to ion channels. Frontiers in Physiology. 5: 65. PMID 24616704 DOI: 10.3389/Fphys.2014.00065 |
0.52 |
|
2014 |
Rosenhouse-Dantsker A, Noskov S, Durdagi S, Logothetis DE, Levitan I. Identification of Novel Cholesterol Binding Regions in the Transmembrane Domain of Kir2.1 Biophysical Journal. 106: 747a. DOI: 10.1016/J.Bpj.2013.11.4117 |
0.482 |
|
2014 |
Bukiya AN, Osborn CV, Toth PT, Kowalsky G, Baki L, Oh MJ, Levitan I, Rosenhouse-Dantsker A. Cholesterol Regulation of Atrial GIRk Channels Biophysical Journal. 106: 747. DOI: 10.1016/J.Bpj.2013.11.4116 |
0.542 |
|
2013 |
Gundavaram MS, Shentu TP, Kowalsky GB, Volkov S, Schraufnagel DE, Levitan I. Oxidized low-density lipoprotein alters the effect of matrix stiffness on the formation of endothelial networks and capillary lumens. Pulmonary Circulation. 3: 622-31. PMID 24618546 DOI: 10.1086/674309 |
0.363 |
|
2013 |
Rosenhouse-Dantsker A, Noskov S, Durdagi S, Logothetis DE, Levitan I. Identification of novel cholesterol-binding regions in Kir2 channels. The Journal of Biological Chemistry. 288: 31154-64. PMID 24019518 DOI: 10.1074/Jbc.M113.496117 |
0.528 |
|
2013 |
Rosenhouse-Dantsker A, Noskov S, Logothetis DE, Levitan I. Cholesterol sensitivity of KIR2.1 depends on functional inter-links between the N and C termini. Channels (Austin, Tex.). 7: 303-12. PMID 23807091 DOI: 10.4161/Chan.25437 |
0.496 |
|
2013 |
Hong Z, Ersoy I, Sun M, Bunyak F, Hampel P, Hong Z, Sun Z, Li Z, Levitan I, Meininger GA, Palaniappan K. Influence of membrane cholesterol and substrate elasticity on endothelial cell spreading behavior. Journal of Biomedical Materials Research. Part A. 101: 1994-2004. PMID 23239612 DOI: 10.1002/Jbm.A.34504 |
0.462 |
|
2013 |
Thomas J, Metcalf J, Christman JW, Cook J, Levitan I. Role of K+ Channels in Alveolar Macrophages-Mediated Inflammatory Response upon Anthrax Lethal Toxin Stimulation Biophysical Journal. 104: 1-2. DOI: 10.1016/J.Bpj.2012.11.755 |
0.381 |
|
2013 |
Levitan I. Mechanisms of Cholesterol Regulation of Kir Channels Biophysical Journal. 104. DOI: 10.1016/J.Bpj.2012.11.3012 |
0.565 |
|
2013 |
Han H, Rosenhouse-Dantsker A, Epshtein Y, Chen Z, Kowalsky G, Shinin V, Minshall R, Levitan I. Caveolin-1 Regulates Kir2.1 Channel activity through Interaction with Cholesterol Biophysical Journal. 104: 4-4. DOI: 10.1016/J.Bpj.2012.11.2569 |
0.547 |
|
2013 |
Rosenhouse-Dantsker A, Logothetis DE, Levitan I. Coupling between the N- and C- Termini of Kir2.1 is Critical for Cholesterol Modulation Biophysical Journal. 104: 440a. DOI: 10.1016/J.Bpj.2012.11.2444 |
0.544 |
|
2013 |
Rosenhouse-Dantsker A, Noskov S, Han H, Adney SK, Tang Q, Rodríguez-Menchaca AA, Kowalsky GB, Petrou VI, Osborn CV, Logothetis DE, Levitan I. Distant Cytosolic Residues in Kir Channels Control Channel Gating and Modulation by Cholesterol and PI(4,5)P2 Biophysical Journal. 104: 24a-25a. DOI: 10.1016/J.Bpj.2012.11.169 |
0.535 |
|
2012 |
Rosenhouse-Dantsker A, Mehta D, Levitan I. Regulation of ion channels by membrane lipids. Comprehensive Physiology. 2: 31-68. PMID 23728970 DOI: 10.1002/Cphy.C110001 |
0.517 |
|
2012 |
Hong Z, Staiculescu MC, Hampel P, Levitan I, Forgacs G. How cholesterol regulates endothelial biomechanics. Frontiers in Physiology. 3: 426. PMID 23162471 DOI: 10.3389/Fphys.2012.00426 |
0.51 |
|
2012 |
Rosenhouse-Dantsker A, Noskov S, Han H, Adney SK, Tang QY, Rodríguez-Menchaca AA, Kowalsky GB, Petrou VI, Osborn CV, Logothetis DE, Levitan I. Distant cytosolic residues mediate a two-way molecular switch that controls the modulation of inwardly rectifying potassium (Kir) channels by cholesterol and phosphatidylinositol 4,5-bisphosphate (PI(4,5)P(2)). The Journal of Biological Chemistry. 287: 40266-78. PMID 22995912 DOI: 10.1074/Jbc.M111.336339 |
0.528 |
|
2012 |
Stroka KM, Levitan I, Aranda-Espinoza H. OxLDL and substrate stiffness promote neutrophil transmigration by enhanced endothelial cell contractility and ICAM-1. Journal of Biomechanics. 45: 1828-34. PMID 22560286 DOI: 10.1016/J.Jbiomech.2012.04.011 |
0.328 |
|
2012 |
Shentu TP, Singh DK, Oh MJ, Sun S, Sadaat L, Makino A, Mazzone T, Subbaiah PV, Cho M, Levitan I. The role of oxysterols in control of endothelial stiffness. Journal of Lipid Research. 53: 1348-58. PMID 22496390 DOI: 10.1194/Jlr.M027102 |
0.392 |
|
2012 |
Deng W, Bukiya AN, Rodríguez-Menchaca AA, Zhang Z, Baumgarten CM, Logothetis DE, Levitan I, Rosenhouse-Dantsker A. Hypercholesterolemia induces up-regulation of KACh cardiac currents via a mechanism independent of phosphatidylinositol 4,5-bisphosphate and Gβγ. The Journal of Biological Chemistry. 287: 4925-35. PMID 22174416 DOI: 10.1074/Jbc.M111.306134 |
0.415 |
|
2012 |
Oshikawa J, Kim SJ, Furuta E, Caliceti C, Chen GF, McKinney RD, Kuhr F, Levitan I, Fukai T, Ushio-Fukai M. Novel role of p66Shc in ROS-dependent VEGF signaling and angiogenesis in endothelial cells. American Journal of Physiology. Heart and Circulatory Physiology. 302: H724-32. PMID 22101521 DOI: 10.1152/Ajpheart.00739.2011 |
0.357 |
|
2012 |
Deng W, Bukiya AN, Rodríguez-Menchaca AA, Zhang Z, Baumgarten CM, Logothetis DE, Levitan I, Rosenhouse-Dantsker A. Hypercholesterolemia Induces Upregulation of KACh Cardiac Currents Biophysical Journal. 102: 301a. DOI: 10.1016/J.Bpj.2011.11.1664 |
0.516 |
|
2012 |
Rosenhouse-Dantsker A, Noskov S, Rodríguez-Menchaca AA, Logothetis DE, Levitan I. Modulation of Kir Channels by Cholesterol and PI(4,5)P2 Is Controlled by a Two-Way Molecular Switch Biophysical Journal. 102: 18a. DOI: 10.1016/J.Bpj.2011.11.123 |
0.541 |
|
2011 |
Kowalsky GB, Beam D, Oh MJ, Sachs F, Hua SZ, Levitan I. Cholesterol depletion facilitates recovery from hypotonic cell swelling in CHO cells. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 28: 1247-54. PMID 22179012 DOI: 10.1159/000335856 |
0.442 |
|
2011 |
Singh DK, Shentu TP, Enkvetchakul D, Levitan I. Cholesterol regulates prokaryotic Kir channel by direct binding to channel protein. Biochimica Et Biophysica Acta. 1808: 2527-33. PMID 21798234 DOI: 10.1016/J.Bbamem.2011.07.006 |
0.515 |
|
2011 |
Levitan I, Shentu TP. Impact of oxLDL on Cholesterol-Rich Membrane Rafts. Journal of Lipids. 2011: 730209. PMID 21490811 DOI: 10.1155/2011/730209 |
0.442 |
|
2011 |
Thomas J, Epshtein Y, Chopra A, Ordog B, Ghassemi M, Christman JW, Nattel S, Cook JL, Levitan I. Anthrax lethal factor activates K(+) channels to induce IL-1β secretion in macrophages. Journal of Immunology (Baltimore, Md. : 1950). 186: 5236-43. PMID 21421849 DOI: 10.4049/Jimmunol.1001078 |
0.367 |
|
2011 |
Rosenhouse-Dantsker A, Logothetis DE, Levitan I. Cholesterol sensitivity of KIR2.1 is controlled by a belt of residues around the cytosolic pore. Biophysical Journal. 100: 381-9. PMID 21244834 DOI: 10.1016/J.Bpj.2010.11.086 |
0.517 |
|
2011 |
Rosenhouse-Dantsker A, Logothetis DE, Levitan I. Cholesterol Sensitivity of Kir2.1 is Modulated by a Cytosolic Belt: Implications for Kir Gating Biophysical Journal. 100: 99a. DOI: 10.1016/J.Bpj.2010.12.749 |
0.516 |
|
2011 |
Singh D, Shentu T, Enkvetchakul D, Levitan I. Cholesterol Binding Regulates Prokaryotic Kir Channels Biophysical Journal. 100. DOI: 10.1016/J.Bpj.2010.12.2542 |
0.51 |
|
2011 |
Shentu TP, Singh DK, Subbaiah P, Cho M, Levitan I. Identification of oxLDL Components Affecting Endothelial Stiffness Biophysical Journal. 100: 160a. DOI: 10.1016/J.Bpj.2010.12.1091 |
0.427 |
|
2010 |
Norman LL, Oetama RJ, Dembo M, Byfield F, Hammer DA, Levitan I, Aranda-Espinoza H. Modification of Cellular Cholesterol Content Affects Traction Force, Adhesion and Cell Spreading. Cellular and Molecular Bioengineering. 3: 151-162. PMID 21461187 DOI: 10.1007/S12195-010-0119-X |
0.475 |
|
2010 |
Shentu TP, Titushkin I, Singh DK, Gooch KJ, Subbaiah PV, Cho M, Levitan I. oxLDL-induced decrease in lipid order of membrane domains is inversely correlated with endothelial stiffness and network formation. American Journal of Physiology. Cell Physiology. 299: C218-29. PMID 20410437 DOI: 10.1152/Ajpcell.00383.2009 |
0.469 |
|
2010 |
Levitan I, Fang Y, Rosenhouse-Dantsker A, Romanenko V. Cholesterol and ion channels. Sub-Cellular Biochemistry. 51: 509-49. PMID 20213557 DOI: 10.1007/978-90-481-8622-8_19 |
0.519 |
|
2010 |
Rosenhouse-Dantsker A, Leal-Pinto E, Logothetis DE, Levitan I. Comparative analysis of cholesterol sensitivity of Kir channels: role of the CD loop. Channels (Austin, Tex.). 4: 63-6. PMID 19923917 DOI: 10.4161/Chan.4.1.10366 |
0.533 |
|
2010 |
Levitan I, Volkov S, Subbaiah PV. Oxidized LDL: diversity, patterns of recognition, and pathophysiology. Antioxidants & Redox Signaling. 13: 39-75. PMID 19888833 DOI: 10.1089/Ars.2009.2733 |
0.328 |
|
2010 |
Hong Z, Hampel P, Staiculescu MC, Levitan I, Forgacs G. Cholesterol and Phosphatidylinositol 4,5-Bisphosphate Synergistically Affect Endothelial Biomechanics Biophysical Journal. 98: 426a. DOI: 10.1016/J.Bpj.2009.12.2306 |
0.509 |
|
2010 |
Kowalsky G, Beam D, Sachs F, Hua S, Levitan I. Cholesterol Depletion Facilitates Recovery from Hypotonic Cell Swelling of CHO Biophysical Journal. 98: 318a. DOI: 10.1016/J.Bpj.2009.12.1727 |
0.44 |
|
2010 |
Rosenhouse-Dantsker A, Leal-Pinto E, Logothetis DE, Levitan I. Comparative Analysis of Cholesterol Sensitivity of Kir Channels: Role of the Cytoplasmic Domain Biophysical Journal. 98: 213a. DOI: 10.1016/J.Bpj.2009.12.1147 |
0.547 |
|
2009 |
Singh DK, Rosenhouse-Dantsker A, Nichols CG, Enkvetchakul D, Levitan I. Direct regulation of prokaryotic Kir channel by cholesterol. The Journal of Biological Chemistry. 284: 30727-36. PMID 19740741 DOI: 10.1074/Jbc.M109.011221 |
0.54 |
|
2009 |
Levitan I. Cholesterol and Kir channels. Iubmb Life. 61: 781-90. PMID 19548316 DOI: 10.1002/Iub.192 |
0.538 |
|
2009 |
Epshtein Y, Chopra AP, Rosenhouse-Dantsker A, Kowalsky GB, Logothetis DE, Levitan I. Identification of a C-terminus domain critical for the sensitivity of Kir2.1 to cholesterol. Proceedings of the National Academy of Sciences of the United States of America. 106: 8055-60. PMID 19416905 DOI: 10.1073/Pnas.0809847106 |
0.531 |
|
2009 |
Byfield FJ, Reen RK, Shentu TP, Levitan I, Gooch KJ. Endothelial actin and cell stiffness is modulated by substrate stiffness in 2D and 3D. Journal of Biomechanics. 42: 1114-9. PMID 19356760 DOI: 10.1016/J.Jbiomech.2009.02.012 |
0.319 |
|
2009 |
Epshtein Y, Minshall R, Levitan I. Role of Kir 2-caveolin-1 interactions in the sensitivity of Kir to cholesterol Biophysical Journal. 96. DOI: 10.1016/J.Bpj.2008.12.2380 |
0.544 |
|
2009 |
Hong Z, Staiculescu M, Sun M, Levitan I, Forgacs G. How Phosphatidylinositol 4,5-bisphosphate Regulates Membrane-Cytoskeleton Interaction in Endothelial Cells? Biophysical Journal. 96: 395a. DOI: 10.1016/J.Bpj.2008.12.2009 |
0.399 |
|
2009 |
Levitan I. Structural Determinants of the Regulation of Kir Channels by Cholesterol Biophysical Journal. 96: 2-5. DOI: 10.1016/J.Bpj.2008.12.1827 |
0.556 |
|
2009 |
Shentu T, Titushkin I, Cho M, Levitan I. Impact Of Oxysterols On Endothelial Elastic Properties, Contractility And Morphogenesis Biophysical Journal. 96: 3-6. DOI: 10.1016/J.Bpj.2008.12.1584 |
0.485 |
|
2008 |
Kowalsky GB, Byfield FJ, Levitan I. oxLDL facilitates flow-induced realignment of aortic endothelial cells. American Journal of Physiology. Cell Physiology. 295: C332-40. PMID 18562483 DOI: 10.1152/Ajpcell.00335.2007 |
0.422 |
|
2008 |
Singh DK, Enkvetchakul D, Nichols CG, Levitan I. Kirbac 1.1 activity in liposomes is suppressed by cholesterol The Faseb Journal. 22: 84-84. DOI: 10.1096/Fasebj.22.2_Supplement.84 |
0.479 |
|
2007 |
Levitan I, Gooch KJ. Lipid rafts in membrane-cytoskeleton interactions and control of cellular biomechanics: actions of oxLDL. Antioxidants & Redox Signaling. 9: 1519-34. PMID 17576163 DOI: 10.1089/Ars.2007.1686 |
0.474 |
|
2007 |
Sun M, Northup N, Marga F, Huber T, Byfield FJ, Levitan I, Forgacs G. The effect of cellular cholesterol on membrane-cytoskeleton adhesion. Journal of Cell Science. 120: 2223-31. PMID 17550968 DOI: 10.1242/Jcs.001370 |
0.45 |
|
2007 |
Zidovetzki R, Levitan I. Use of cyclodextrins to manipulate plasma membrane cholesterol content: evidence, misconceptions and control strategies. Biochimica Et Biophysica Acta. 1768: 1311-24. PMID 17493580 DOI: 10.1016/J.Bbamem.2007.03.026 |
0.466 |
|
2007 |
Mohler ER, Fang Y, Shaffer RG, Moore J, Wilensky RL, Parmacek M, Levitan I. Hypercholesterolemia suppresses Kir channels in porcine bone marrow progenitor cells in vivo. Biochemical and Biophysical Research Communications. 358: 317-24. PMID 17482574 DOI: 10.1016/J.Bbrc.2007.04.138 |
0.476 |
|
2007 |
Tikku S, Epshtein Y, Collins H, Travis AJ, Rothblat GH, Levitan I. Relationship between Kir2.1/Kir2.3 activity and their distributions between cholesterol-rich and cholesterol-poor membrane domains. American Journal of Physiology. Cell Physiology. 293: C440-50. PMID 17459945 DOI: 10.1152/Ajpcell.00492.2006 |
0.549 |
|
2006 |
Chatterjee S, Levitan I, Wei Z, Fisher AB. KATP channels are an important component of the shear-sensing mechanism in the pulmonary microvasculature. Microcirculation (New York, N.Y. : 1994). 13: 633-44. PMID 17085424 DOI: 10.1080/10739680600930255 |
0.432 |
|
2006 |
Byfield FJ, Hoffman BD, Romanenko VG, Fang Y, Crocker JC, Levitan I. Evidence for the role of cell stiffness in modulation of volume-regulated anion channels. Acta Physiologica (Oxford, England). 187: 285-94. PMID 16734765 DOI: 10.1111/J.1748-1716.2006.01555.X |
0.414 |
|
2006 |
Fang Y, Mohler ER, Hsieh E, Osman H, Hashemi SM, Davies PF, Rothblat GH, Wilensky RL, Levitan I. Hypercholesterolemia suppresses inwardly rectifying K+ channels in aortic endothelium in vitro and in vivo. Circulation Research. 98: 1064-71. PMID 16556870 DOI: 10.1161/01.Res.0000218776.87842.43 |
0.526 |
|
2006 |
Byfield FJ, Tikku S, Rothblat GH, Gooch KJ, Levitan I. OxLDL increases endothelial stiffness, force generation, and network formation. Journal of Lipid Research. 47: 715-23. PMID 16418538 DOI: 10.1194/Jlr.M500439-Jlr200 |
0.45 |
|
2006 |
Fang Y, Rothblat GH, Davies PF, Levitan I. Hypercholesterolemia impairs shear stress-induced hyperpolarization of endothelial cells Vascular Pharmacology. 45. DOI: 10.1016/J.Vph.2006.08.151 |
0.312 |
|
2006 |
Fang Y, Shaffer RG, Moore J, Mohler E, Levitan I. Hypercholesterolemia alters the functional properties of inwardly-rectifying K channels in side-population endothelial progenitor cells in a pig model Vascular Pharmacology. 45. DOI: 10.1016/J.Vph.2006.08.118 |
0.419 |
|
2005 |
Fang Y, Schram G, Romanenko VG, Shi C, Conti L, Vandenberg CA, Davies PF, Nattel S, Levitan I. Functional expression of Kir2.x in human aortic endothelial cells: the dominant role of Kir2.2. American Journal of Physiology. Cell Physiology. 289: C1134-44. PMID 15958527 DOI: 10.1152/Ajpcell.00077.2005 |
0.418 |
|
2004 |
Romanenko VG, Fang Y, Byfield F, Travis AJ, Vandenberg CA, Rothblat GH, Levitan I. Cholesterol sensitivity and lipid raft targeting of Kir2.1 channels. Biophysical Journal. 87: 3850-61. PMID 15465867 DOI: 10.1529/Biophysj.104.043273 |
0.569 |
|
2004 |
Byfield FJ, Aranda-Espinoza H, Romanenko VG, Rothblat GH, Levitan I. Cholesterol depletion increases membrane stiffness of aortic endothelial cells. Biophysical Journal. 87: 3336-43. PMID 15347591 DOI: 10.1529/Biophysj.104.040634 |
0.492 |
|
2004 |
Romanenko VG, Rothblat GH, Levitan I. Sensitivity of volume-regulated anion current to cholesterol structural analogues. The Journal of General Physiology. 123: 77-87. PMID 14699079 DOI: 10.1085/Jgp.200308882 |
0.504 |
|
2004 |
Fang Y, Romanenko V, Shi C, Schram G, Nattel S, Davies PF, Levitan I. MOLECULAR IDENTIFICATION OF HETEROTETRAMERIC K+ CHANNELS IN HUMAN AORTIC ENDOTHELIAL CELLS: A DOMINANT CONTRIBUTION OF KIR2.1 AND KIR2.2 Cardiovascular Pathology. 13: 195-196. DOI: 10.1016/J.Carpath.2004.03.590 |
0.422 |
|
2003 |
Chatterjee S, Al-Mehdi AB, Levitan I, Stevens T, Fisher AB. Shear stress increases expression of a KATP channel in rat and bovine pulmonary vascular endothelial cells. American Journal of Physiology. Cell Physiology. 285: C959-67. PMID 12826604 DOI: 10.1152/Ajpcell.00511.2002 |
0.48 |
|
2003 |
Sun AC, Levitan I. Osmotic stress alters the intracellular distribution of non-erythroidal spectrin (fodrin) in bovine aortic endothelial cells. The Journal of Membrane Biology. 192: 9-17. PMID 12647030 DOI: 10.1007/S00232-002-1060-2 |
0.367 |
|
2002 |
Romanenko VG, Rothblat GH, Levitan I. Modulation of endothelial inward-rectifier K+ current by optical isomers of cholesterol. Biophysical Journal. 83: 3211-22. PMID 12496090 DOI: 10.1016/S0006-3495(02)75323-X |
0.557 |
|
2002 |
Romanenko VG, Davies PF, Levitan I. Dual effect of fluid shear stress on volume-regulated anion current in bovine aortic endothelial cells. American Journal of Physiology. Cell Physiology. 282: C708-18. PMID 11880259 DOI: 10.1152/Ajpcell.00247.2001 |
0.317 |
|
2000 |
Levitan I, Helmke BP, Davies PF. A chamber to permit invasive manipulation of adherent cells in laminar flow with minimal disturbance of the flow field. Annals of Biomedical Engineering. 28: 1184-93. PMID 11144979 DOI: 10.1114/1.1317529 |
0.318 |
|
2000 |
Levitan I, Christian AE, Tulenko TN, Rothblat GH. Membrane cholesterol content modulates activation of volume-regulated anion current in bovine endothelial cells. The Journal of General Physiology. 115: 405-16. PMID 10736308 DOI: 10.1085/Jgp.115.4.405 |
0.549 |
|
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