Chih-Hao Lee - Publications

Harvard University, Cambridge, MA, United States 
Biochemistry, Public Health, Aging

45 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Dai L, Bhargava P, Stanya KJ, Alexander RK, Liou YH, Jacobi D, Knudsen NH, Hyde A, Gangl MR, Liu S, Lee CH. Macrophage alternative activation confers protection against lipotoxicity-induced cell death. Molecular Metabolism. 6: 1186-1197. PMID 29031719 DOI: 10.1016/j.molmet.2017.08.001  1
2017 Wang DD, Toledo E, Hruby A, Rosner BA, Willett WC, Sun Q, Razquin C, Zheng Y, Ruiz-Canela M, Guasch-Ferré M, Corella D, Gómez-Gracia E, Fiol M, Estruch R, Ros E, ... ... Lee CH, et al. Plasma Ceramides, Mediterranean Diet, and Incident Cardiovascular Disease in the PREDIMED Trial. Circulation. PMID 28280233 DOI: 10.1161/CIRCULATIONAHA.116.024261  0.32
2016 McCarthy RC, Lu DY, Alkhateeb A, Gardeck AM, Lee CH, Wessling-Resnick M. Characterization of a novel adult murine immortalized microglial cell line and its activation by amyloid-beta. Journal of Neuroinflammation. 13: 21. PMID 26819091 DOI: 10.1186/s12974-016-0484-z  1
2015 Zhou Y, Yu X, Chen H, Sjöberg S, Roux J, Zhang L, Ivoulsou AH, Bensaid F, Liu CL, Liu J, Tordjman J, Clement K, Lee CH, Hotamisligil GS, Libby P, et al. Leptin Deficiency Shifts Mast Cells toward Anti-Inflammatory Actions and Protects Mice from Obesity and Diabetes by Polarizing M2 Macrophages. Cell Metabolism. PMID 26481668 DOI: 10.1016/j.cmet.2015.09.013  1
2015 Jacobi D, Liu S, Burkewitz K, Kory N, Knudsen NH, Alexander RK, Unluturk U, Li X, Kong X, Hyde AL, Gangl MR, Mair WB, Lee CH. Hepatic Bmal1 Regulates Rhythmic Mitochondrial Dynamics and Promotes Metabolic Fitness. Cell Metabolism. PMID 26365180 DOI: 10.1016/j.cmet.2015.08.006  1
2015 Qiu YQ, Yang CW, Lee YZ, Yang RB, Lee CH, Hsu HY, Chang CC, Lee SJ. Targeting a ribonucleoprotein complex containing the caprin-1 protein and the c-Myc mRNA suppresses tumor growth in mice: an identification of a novel oncotarget. Oncotarget. 6: 2148-63. PMID 25669982  1
2014 Lee YZ, Yang CW, Chang HY, Hsu HY, Chen IS, Chang HS, Lee CH, Lee JC, Kumar CR, Qiu YQ, Chao YS, Lee SJ. Discovery of selective inhibitors of Glutaminase-2, which inhibit mTORC1, activate autophagy and inhibit proliferation in cancer cells. Oncotarget. 5: 6087-101. PMID 25026281  1
2014 Liu S, Alexander RK, Lee CH. Lipid metabolites as metabolic messengers in inter-organ communication. Trends in Endocrinology and Metabolism: Tem. 25: 356-63. PMID 24895003 DOI: 10.1016/j.tem.2014.05.002  0.32
2014 Huang BR, Chang PC, Yeh WL, Lee CH, Tsai CF, Lin C, Lin HY, Liu YS, Wu CY, Ko PY, Huang SS, Hsu HC, Lu DY. Anti-neuroinflammatory effects of the calcium channel blocker nicardipine on microglial cells: implications for neuroprotection. Plos One. 9: e91167. PMID 24621589 DOI: 10.1371/journal.pone.0091167  1
2014 Lin HY, Huang BR, Yeh WL, Lee CH, Huang SS, Lai CH, Lin H, Lu DY. Antineuroinflammatory effects of lycopene via activation of adenosine monophosphate-activated protein kinase-α1/heme oxygenase-1 pathways. Neurobiology of Aging. 35: 191-202. PMID 23906616 DOI: 10.1016/j.neurobiolaging.2013.06.020  1
2013 Liu S, Brown JD, Stanya KJ, Homan E, Leidl M, Inouye K, Bhargava P, Gangl MR, Dai L, Hatano B, Hotamisligil GS, Saghatelian A, Plutzky J, Lee CH. A diurnal serum lipid integrates hepatic lipogenesis and peripheral fatty acid use. Nature. 502: 550-4. PMID 24153306 DOI: 10.1038/nature12710  1
2013 DeSantis DA, Lee P, Doerner SK, Ko CW, Kawasoe JH, Hill-Baskin AE, Ernest SR, Bhargava P, Hur KY, Cresci GA, Pritchard MT, Lee CH, Nagy LE, Nadeau JH, Croniger CM. Genetic resistance to liver fibrosis on A/J mouse chromosome 17. Alcoholism, Clinical and Experimental Research. 37: 1668-79. PMID 23763294 DOI: 10.1111/acer.12157  1
2013 Jia X, Kim J, Veuthey T, Lee CH, Wessling-Resnick M. Glucose metabolism in the Belgrade rat, a model of iron-loading anemia. American Journal of Physiology. Gastrointestinal and Liver Physiology. 304: G1095-102. PMID 23599042 DOI: 10.1152/ajpgi.00453.2012  1
2013 Stanya KJ, Jacobi D, Liu S, Bhargava P, Dai L, Gangl MR, Inouye K, Barlow JL, Ji Y, Mizgerd JP, Qi L, Shi H, McKenzie AN, Lee CH. Direct control of hepatic glucose production by interleukin-13 in mice. The Journal of Clinical Investigation. 123: 261-71. PMID 23257358 DOI: 10.1172/JCI64941  1
2013 Kim J, Jia X, Buckett PD, Liu S, Lee CH, Wessling-Resnick M. Iron loading impairs lipoprotein lipase activity and promotes hypertriglyceridemia. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 1657-63. PMID 23241313 DOI: 10.1096/fj.12-224386  0.32
2013 Liu S, Reilly SM, Lee CH. Transcriptional repression of mitochondrial function in aging: a novel role for the silencing mediator of retinoid and thyroid hormone receptors co-repressor. Antioxidants & Redox Signaling. 19: 299-309. PMID 22703297 DOI: 10.1089/ars.2011.4413  1
2012 Bhargava P, Li C, Stanya KJ, Jacobi D, Dai L, Liu S, Gangl MR, Harn DA, Lee CH. Immunomodulatory glycan LNFPIII alleviates hepatosteatosis and insulin resistance through direct and indirect control of metabolic pathways. Nature Medicine. 18: 1665-72. PMID 23104131 DOI: 10.1038/nm.2962  1
2012 Ito K, Carracedo A, Weiss D, Arai F, Ala U, Avigan DE, Schafer ZT, Evans RM, Suda T, Lee CH, Pandolfi PP. A PML–PPAR-δ pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance. Nature Medicine. 18: 1350-8. PMID 22902876 DOI: 10.1038/nm.2882  1
2012 Zhang Y, Li Y, Niepel MW, Kawano Y, Han S, Liu S, Marsili A, Larsen PR, Lee CH, Cohen DE. Targeted deletion of thioesterase superfamily member 1 promotes energy expenditure and protects against obesity and insulin resistance. Proceedings of the National Academy of Sciences of the United States of America. 109: 5417-22. PMID 22427358 DOI: 10.1073/pnas.1116011109  1
2012 Ji Y, Sun S, Xu A, Bhargava P, Yang L, Lam KS, Gao B, Lee CH, Kersten S, Qi L. Activation of natural killer T cells promotes M2 Macrophage polarization in adipose tissue and improves systemic glucose tolerance via interleukin-4 (IL-4)/STAT6 protein signaling axis in obesity. The Journal of Biological Chemistry. 287: 13561-71. PMID 22396530 DOI: 10.1074/jbc.M112.350066  1
2012 Bhargava P, Lee CH. Role and function of macrophages in the metabolic syndrome. The Biochemical Journal. 442: 253-62. PMID 22329799 DOI: 10.1042/BJ20111708  1
2011 Cho SH, Ahn AK, Bhargava P, Lee CH, Eischen CM, McGuinness O, Boothby M. Glycolytic rate and lymphomagenesis depend on PARP14, an ADP ribosyltransferase of the B aggressive lymphoma (BAL) family. Proceedings of the National Academy of Sciences of the United States of America. 108: 15972-7. PMID 21911376 DOI: 10.1073/pnas.1017082108  1
2011 Yecies JL, Zhang HH, Menon S, Liu S, Yecies D, Lipovsky AI, Gorgun C, Kwiatkowski DJ, Hotamisligil GS, Lee CH, Manning BD. Akt stimulates hepatic SREBP1c and lipogenesis through parallel mTORC1-dependent and independent pathways. Cell Metabolism. 14: 21-32. PMID 21723501 DOI: 10.1016/j.cmet.2011.06.002  1
2011 Liu S, Hatano B, Zhao M, Yen CC, Kang K, Reilly SM, Gangl MR, Gorgun C, Balschi JA, Ntambi JM, Lee CH. Role of peroxisome proliferator-activated receptor {delta}/{beta} in hepatic metabolic regulation. The Journal of Biological Chemistry. 286: 1237-47. PMID 21059653 DOI: 10.1074/jbc.M110.138115  1
2010 Reilly SM, Bhargava P, Liu S, Gangl MR, Gorgun C, Nofsinger RR, Evans RM, Qi L, Hu FB, Lee CH. Nuclear receptor corepressor SMRT regulates mitochondrial oxidative metabolism and mediates aging-related metabolic deterioration. Cell Metabolism. 12: 643-53. PMID 21109196 DOI: 10.1016/j.cmet.2010.11.007  1
2010 Qi L, Cornelis MC, Kraft P, Stanya KJ, Linda Kao WH, Pankow JS, Dupuis J, Florez JC, Fox CS, Paré G, Sun Q, Girman CJ, Laurie CC, Mirel DB, Manolio TA, ... ... Lee CH, et al. Genetic variants at 2q24 are associated with susceptibility to type 2 diabetes. Human Molecular Genetics. 19: 2706-15. PMID 20418489 DOI: 10.1093/hmg/ddq156  1
2010 Krishnamoorthy S, Recchiuti A, Chiang N, Yacoubian S, Lee CH, Yang R, Petasis NA, Serhan CN. Resolvin D1 binds human phagocytes with evidence for proresolving receptors. Proceedings of the National Academy of Sciences of the United States of America. 107: 1660-5. PMID 20080636 DOI: 10.1073/pnas.0907342107  1
2008 Nofsinger RR, Li P, Hong SH, Jonker JW, Barish GD, Ying H, Cheng SY, Leblanc M, Xu W, Pei L, Kang YJ, Nelson M, Downes M, Yu RT, Olefsky JM, ... Lee CH, et al. SMRT repression of nuclear receptors controls the adipogenic set point and metabolic homeostasis. Proceedings of the National Academy of Sciences of the United States of America. 105: 20021-6. PMID 19066220 DOI: 10.1073/pnas.0811012105  1
2008 Qi L, Kang K, Zhang C, van Dam RM, Kraft P, Hunter D, Lee CH, Hu FB. Fat mass-and obesity-associated (FTO) gene variant is associated with obesity: longitudinal analyses in two cohort studies and functional test. Diabetes. 57: 3145-51. PMID 18647953 DOI: 10.2337/db08-0006  0.4
2008 Kang K, Reilly SM, Karabacak V, Gangl MR, Fitzgerald K, Hatano B, Lee CH. Adipocyte-derived Th2 cytokines and myeloid PPARdelta regulate macrophage polarization and insulin sensitivity. Cell Metabolism. 7: 485-95. PMID 18522830 DOI: 10.1016/j.cmet.2008.04.002  1
2008 Barish GD, Atkins AR, Downes M, Olson P, Chong LW, Nelson M, Zou Y, Hwang H, Kang H, Curtiss L, Evans RM, Lee CH. PPARdelta regulates multiple proinflammatory pathways to suppress atherosclerosis. Proceedings of the National Academy of Sciences of the United States of America. 105: 4271-6. PMID 18337509 DOI: 10.1073/pnas.0711875105  1
2008 Takata Y, Liu J, Yin F, Collins AR, Lyon CJ, Lee CH, Atkins AR, Downes M, Barish GD, Evans RM, Hsueh WA, Tangirala RK. PPARdelta-mediated antiinflammatory mechanisms inhibit angiotensin II-accelerated atherosclerosis. Proceedings of the National Academy of Sciences of the United States of America. 105: 4277-82. PMID 18337495 DOI: 10.1073/pnas.0708647105  1
2008 Reilly SM, Lee CH. PPAR delta as a therapeutic target in metabolic disease. Febs Letters. 582: 26-31. PMID 18036566 DOI: 10.1016/j.febslet.2007.11.040  1
2007 Sonoda J, Laganière J, Mehl IR, Barish GD, Chong LW, Li X, Scheffler IE, Mock DC, Bataille AR, Robert F, Lee CH, Giguère V, Evans RM. Nuclear receptor ERR alpha and coactivator PGC-1 beta are effectors of IFN-gamma-induced host defense. Genes & Development. 21: 1909-20. PMID 17671090 DOI: 10.1101/gad.1553007  1
2007 Kang K, Hatano B, Lee CH. PPAR delta agonists and metabolic diseases. Current Atherosclerosis Reports. 9: 72-7. PMID 17169250  0.4
2006 Lee CH, Olson P, Hevener A, Mehl I, Chong LW, Olefsky JM, Gonzalez FJ, Ham J, Kang H, Peters JM, Evans RM. PPARdelta regulates glucose metabolism and insulin sensitivity. Proceedings of the National Academy of Sciences of the United States of America. 103: 3444-9. PMID 16492734 DOI: 10.1073/pnas.0511253103  0.32
2006 Lee CH, Kang K, Mehl IR, Nofsinger R, Alaynick WA, Chong LW, Rosenfeld JM, Evans RM. Peroxisome proliferator-activated receptor delta promotes very low-density lipoprotein-derived fatty acid catabolism in the macrophage. Proceedings of the National Academy of Sciences of the United States of America. 103: 2434-9. PMID 16467150 DOI: 10.1073/pnas.0510815103  1
2005 Sonoda J, Chong LW, Downes M, Barish GD, Coulter S, Liddle C, Lee CH, Evans RM. Pregnane X receptor prevents hepatorenal toxicity from cholesterol metabolites. Proceedings of the National Academy of Sciences of the United States of America. 102: 2198-203. PMID 15671183 DOI: 10.1073/pnas.0409481102  1
2004 Koo SH, Satoh H, Herzig S, Lee CH, Hedrick S, Kulkarni R, Evans RM, Olefsky J, Montminy M. PGC-1 promotes insulin resistance in liver through PPAR-alpha-dependent induction of TRB-3. Nature Medicine. 10: 530-4. PMID 15107844 DOI: 10.1038/nm1044  0.32
2003 Lee CH, Chawla A, Urbiztondo N, Liao D, Boisvert WA, Evans RM, Curtiss LK. Transcriptional repression of atherogenic inflammation: modulation by PPARdelta. Science (New York, N.Y.). 302: 453-7. PMID 12970571 DOI: 10.1126/science.1087344  0.32
2003 Lee CH, Olson P, Evans RM. Minireview: lipid metabolism, metabolic diseases, and peroxisome proliferator-activated receptors. Endocrinology. 144: 2201-7. PMID 12746275 DOI: 10.1210/en.2003-0288  0.32
2003 Wang YX, Lee CH, Tiep S, Yu RT, Ham J, Kang H, Evans RM. Peroxisome-proliferator-activated receptor delta activates fat metabolism to prevent obesity. Cell. 113: 159-70. PMID 12705865  0.32
2003 Chawla A, Lee CH, Barak Y, He W, Rosenfeld J, Liao D, Han J, Kang H, Evans RM. PPARdelta is a very low-density lipoprotein sensor in macrophages. Proceedings of the National Academy of Sciences of the United States of America. 100: 1268-73. PMID 12540828 DOI: 10.1073/pnas.0337331100  0.32
2002 Lee CH, Evans RM. Peroxisome proliferator-activated receptor-gamma in macrophage lipid homeostasis. Trends in Endocrinology and Metabolism: Tem. 13: 331-5. PMID 12217489  0.32
2002 Kao HY, Lee CH, Komarov A, Han CC, Evans RM. Isolation and characterization of mammalian HDAC10, a novel histone deacetylase. The Journal of Biological Chemistry. 277: 187-93. PMID 11677242 DOI: 10.1074/jbc.M108931200  0.32
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