Ze'ev Ronai - Publications

Affiliations: 
Molecular Pathology University of California, San Diego, La Jolla, CA 
Area:
Molecular Biology, Biochemistry, Cell Biology

103 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Claps G, Cheli Y, Zhang T, Scortegagna M, Lau E, Kim H, Qi J, Li JL, James B, Dzung A, Levesque MP, Dummer R, Hayward NK, Bosenberg M, Brown KM, ... Ronai ZA, et al. A Transcriptionally Inactive ATF2 Variant Drives Melanomagenesis. Cell Reports. PMID 27210757 DOI: 10.1016/J.Celrep.2016.04.072  0.56
2016 Merlino G, Herlyn M, Fisher DE, Bastian BC, Flaherty KT, Davies MA, Wargo JA, Curiel-Lewandrowski C, Weber MJ, Leachman SA, Soengas MS, McMahon M, Harbour JW, Swetter SM, Aplin AE, ... ... Ronai ZA, et al. The state of melanoma: challenges and opportunities. Pigment Cell & Melanoma Research. PMID 27087480 DOI: 10.1111/Pcmr.12475  0.56
2015 Lau E, Feng Y, Claps G, Fukuda MN, Perlina A, Donn D, Jilaveanu L, Kluger H, Freeze HH, Ronai ZA. The transcription factor ATF2 promotes melanoma metastasis by suppressing protein fucosylation. Science Signaling. 8: ra124. PMID 26645581 DOI: 10.1126/scisignal.aac6479  0.56
2015 Feng Y, Pinkerton AB, Hulea L, Zhang T, Davies MA, Grotegut S, Cheli Y, Yin H, Lau E, Kim H, De SK, Barile E, Pellecchia M, Bosenberg M, Li JL, ... ... Ronai ZA, et al. SBI-0640756 Attenuates the Growth of Clinically Unresponsive Melanomas by Disrupting the eIF4F Translation Initiation Complex. Cancer Research. PMID 26603897 DOI: 10.1158/0008-5472.Can-15-0885  0.56
2015 Ratnikov B, Jeon YJ, Smith JW, Ronai ZA. Right on TARGET: glutamine metabolism in cancer. Oncoscience. 2: 681-3. PMID 26425657 DOI: 10.18632/oncoscience.205  0.56
2015 Kim H, Frederick DT, Levesque MP, Cooper ZA, Feng Y, Krepler C, Brill L, Samuels Y, Hayward NK, Perlina A, Piris A, Zhang T, Halaban R, Herlyn MM, Brown KM, ... ... Ronai ZA, et al. Downregulation of the Ubiquitin Ligase RNF125 Underlies Resistance of Melanoma Cells to BRAF Inhibitors via JAK1 Deregulation. Cell Reports. 11: 1458-73. PMID 26027934 DOI: 10.1016/J.Celrep.2015.04.049  0.56
2015 Jeon YJ, Khelifa S, Ratnikov B, Scott DA, Feng Y, Parisi F, Ruller C, Lau E, Kim H, Brill LM, Jiang T, Rimm DL, Cardiff RD, Mills GB, Smith JW, ... ... Ronai ZA, et al. Regulation of glutamine carrier proteins by RNF5 determines breast cancer response to ER stress-inducing chemotherapies. Cancer Cell. 27: 354-69. PMID 25759021 DOI: 10.1016/J.Ccell.2015.02.006  0.56
2015 Ratnikov B, Aza-Blanc P, Ronai ZA, Smith JW, Osterman AL, Scott DA. Glutamate and asparagine cataplerosis underlie glutamine addiction in melanoma. Oncotarget. 6: 7379-89. PMID 25749035  0.56
2015 Lau E, Sedy J, Sander C, Shaw MA, Feng Y, Scortegagna M, Claps G, Robinson S, Cheng P, Srivas R, Soonthornvacharin S, Ideker T, Bosenberg M, Gonzalez R, Robinson W, ... ... Ronai ZA, et al. Transcriptional repression of IFNβ1 by ATF2 confers melanoma resistance to therapy. Oncogene. PMID 25728676 DOI: 10.1038/Onc.2015.22  0.56
2015 Scortegagna M, Lau E, Zhang T, Feng Y, Sereduk C, Yin H, De SK, Meeth K, Platt JT, Langdon CG, Halaban R, Pellecchia M, Davies MA, Brown K, Stern DF, ... ... Ronai ZA, et al. PDK1 and SGK3 Contribute to the Growth of BRAF-Mutant Melanomas and Are Potential Therapeutic Targets. Cancer Research. 75: 1399-412. PMID 25712345 DOI: 10.1158/0008-5472.Can-14-2785  0.56
2015 Qi J, Ronai ZA. Dysregulation of ubiquitin ligases in cancer Drug Resistance Updates. 23: 1-11. DOI: 10.1016/j.drup.2015.09.001  0.56
2014 Scortegagna M, Kim H, Li JL, Yao H, Brill LM, Han J, Lau E, Bowtell D, Haddad G, Kaufman RJ, Ronai ZA. Fine tuning of the UPR by the ubiquitin ligases Siah1/2. Plos Genetics. 10: e1004348. PMID 24809345 DOI: 10.1371/Journal.Pgen.1004348  0.56
2014 Maruyama T, Araki T, Kawarazaki Y, Naguro I, Heynen S, Aza-Blanc P, Ronai Z, Matsuzawa A, Ichijo H. Roquin-2 promotes ubiquitin-mediated degradation of ASK1 to regulate stress responses. Science Signaling. 7: ra8. PMID 24448648 DOI: 10.1126/Scisignal.2004822  0.56
2014 Kim H, Claps G, Möller A, Bowtell D, Lu X, Ronai ZA. Siah2 regulates tight junction integrity and cell polarity through control of ASPP2 stability. Oncogene. 33: 2004-10. PMID 23644657 DOI: 10.1038/onc.2013.149  0.56
2013 Grumolato L, Liu G, Haremaki T, Mungamuri SK, Mong P, Akiri G, Lopez-Bergami P, Arita A, Anouar Y, Mlodzik M, Ronai ZA, Brody J, Weinstein DC, Aaronson SA. β-Catenin-independent activation of TCF1/LEF1 in human hematopoietic tumor cells through interaction with ATF2 transcription factors. Plos Genetics. 9: e1003603. PMID 23966864 DOI: 10.1371/Journal.Pgen.1003603  0.56
2013 Stebbins JL, Santelli E, Feng Y, De SK, Purves A, Motamedchaboki K, Wu B, Ronai ZA, Liddington RC, Pellecchia M. Structure-based design of covalent Siah inhibitors. Chemistry & Biology. 20: 973-82. PMID 23891150 DOI: 10.1016/j.chembiol.2013.06.008  0.56
2013 Gandin V, Gutierrez GJ, Brill LM, Varsano T, Feng Y, Aza-Blanc P, Au Q, McLaughlan S, Ferreira TA, Alain T, Sonenberg N, Topisirovic I, Ronai ZA. Degradation of newly synthesized polypeptides by ribosome-associated RACK1/c-Jun N-terminal kinase/eukaryotic elongation factor 1A2 complex. Molecular and Cellular Biology. 33: 2510-26. PMID 23608534 DOI: 10.1128/Mcb.01362-12  0.56
2013 Qi J, Tripathi M, Mishra R, Sahgal N, Fazli L, Fazil L, Ettinger S, Placzek WJ, Claps G, Chung LW, Bowtell D, Gleave M, Bhowmick N, Ronai ZA. The E3 ubiquitin ligase Siah2 contributes to castration-resistant prostate cancer by regulation of androgen receptor transcriptional activity. Cancer Cell. 23: 332-46. PMID 23518348 DOI: 10.1016/J.Ccr.2013.05.018  0.56
2013 Feng Y, Lau E, Scortegagna M, Ruller C, De SK, Barile E, Krajewski S, Aza-Blanc P, Williams R, Pinkerton AB, Jackson M, Chin L, Pellecchia M, Bosenberg M, Ronai ZA. Inhibition of melanoma development in the Nras((Q61K)) ::Ink4a(-/-) mouse model by the small molecule BI-69A11. Pigment Cell & Melanoma Research. 26: 136-42. PMID 23035722 DOI: 10.1111/Pcmr.12033  0.56
2012 Kuang E, Okumura CY, Sheffy-Levin S, Varsano T, Shu VC, Qi J, Niesman IR, Yang HJ, López-Otín C, Yang WY, Reed JC, Broday L, Nizet V, Ronai ZA. Regulation of ATG4B stability by RNF5 limits basal levels of autophagy and influences susceptibility to bacterial infection. Plos Genetics. 8: e1003007. PMID 23093945 DOI: 10.1371/Journal.Pgen.1003007  0.56
2012 De Ingeniis J, Ratnikov B, Richardson AD, Scott DA, Aza-Blanc P, De SK, Kazanov M, Pellecchia M, Ronai Z, Osterman AL, Smith JW. Functional specialization in proline biosynthesis of melanoma. Plos One. 7: e45190. PMID 23024808 DOI: 10.1371/Journal.Pone.0045190  0.56
2012 Lau E, Ronai ZA. ATF2 - at the crossroad of nuclear and cytosolic functions. Journal of Cell Science. 125: 2815-24. PMID 22685333 DOI: 10.1242/jcs.095000  0.56
2012 Yanagiya A, Suyama E, Adachi H, Svitkin YV, Aza-Blanc P, Imataka H, Mikami S, Martineau Y, Ronai ZA, Sonenberg N. Translational homeostasis via the mRNA cap-binding protein, eIF4E. Molecular Cell. 46: 847-58. PMID 22578813 DOI: 10.1016/J.Molcel.2012.04.004  0.56
2012 Chen M, Gutierrez GJ, Ronai ZA. The anaphase-promoting complex or cyclosome supports cell survival in response to endoplasmic reticulum stress. Plos One. 7: e35520. PMID 22539978 DOI: 10.1371/Journal.Pone.0035520  0.56
2012 Filipp FV, Scott DA, Ronai ZA, Osterman AL, Smith JW. Reverse TCA cycle flux through isocitrate dehydrogenases 1 and 2 is required for lipogenesis in hypoxic melanoma cells Pigment Cell and Melanoma Research. 25: 375-383. PMID 22360810 DOI: 10.1111/j.1755-148X.2012.00989.x  0.56
2012 Wong CS, Sceneay J, House CM, Halse HM, Liu MC, George J, Hunnam TC, Parker BS, Haviv I, Ronai Z, Cullinane C, Bowtell DD, Möller A. Vascular normalization by loss of Siah2 results in increased chemotherapeutic efficacy. Cancer Research. 72: 1694-704. PMID 22354750 DOI: 10.1158/0008-5472.Can-11-3310  0.56
2012 Lau E, Kluger H, Varsano T, Lee K, Scheffler I, Rimm DL, Ideker T, Ronai ZA. PKCε promotes oncogenic functions of ATF2 in the nucleus while blocking its apoptotic function at mitochondria. Cell. 148: 543-55. PMID 22304920 DOI: 10.1016/J.Cell.2012.01.016  0.56
2011 Kim H, Scimia MC, Wilkinson D, Trelles RD, Wood MR, Bowtell D, Dillin A, Mercola M, Ronai ZA. Fine-tuning of Drp1/Fis1 availability by AKAP121/Siah2 regulates mitochondrial adaptation to hypoxia. Molecular Cell. 44: 532-44. PMID 22099302 DOI: 10.1016/J.Molcel.2011.08.045  0.56
2011 Scott DA, Richardson AD, Filipp FV, Knutzen CA, Chiang GG, Ronai ZA, Osterman AL, Smith JW. Comparative metabolic flux profiling of melanoma cell lines: beyond the Warburg effect. The Journal of Biological Chemistry. 286: 42626-34. PMID 21998308 DOI: 10.1074/Jbc.M111.282046  0.56
2011 Nagano Y, Fukushima T, Okemoto K, Tanaka K, Bowtell DD, Ronai Z, Reed JC, Matsuzawa S. Siah1/SIP regulates p27(kip1) stability and cell migration under metabolic stress. Cell Cycle (Georgetown, Tex.). 10: 2592-602. PMID 21734459 DOI: 10.4161/cc.10.15.16912  0.56
2011 Feng Y, Barile E, De SK, Stebbins JL, Cortez A, Aza-Blanc P, Villanueva J, Heryln M, Krajewski S, Pellecchia M, Ronai ZA, Chiang GG. Effective inhibition of melanoma by BI-69A11 is mediated by dual targeting of the AKT and NF-κB pathways. Pigment Cell & Melanoma Research. 24: 703-13. PMID 21592316 DOI: 10.1111/J.1755-148X.2011.00867.X  0.56
2011 Chen M, Gutierrez GJ, Ronai ZA. Ubiquitin-recognition protein Ufd1 couples the endoplasmic reticulum (ER) stress response to cell cycle control. Proceedings of the National Academy of Sciences of the United States of America. 108: 9119-24. PMID 21571647 DOI: 10.1073/Pnas.1100028108  0.56
2011 Lau E, Ronai Z. RAF-isotype switching: from B to C through PDE. Nature Structural & Molecular Biology. 18: 517-8. PMID 21540889 DOI: 10.1038/Nsmb.2063  0.56
2010 Li S, Ezhevsky S, Dewing A, Cato MH, Scortegagna M, Bhoumik A, Breitwieser W, Braddock D, Eroshkin A, Qi J, Chen M, Kim JY, Jones S, Jones N, Rickert R, ... Ronai ZA, et al. Radiation Sensitivity and Tumor Susceptibility in ATM Phospho-Mutant ATF2 Mice. Genes & Cancer. 1: 316-330. PMID 20740050 DOI: 10.1177/1947601910370700  0.56
2010 Qi J, Nakayama K, Cardiff RD, Borowsky AD, Kaul K, Williams R, Krajewski S, Mercola D, Carpenter PM, Bowtell D, Ronai ZA. Siah2-dependent concerted activity of HIF and FoxA2 regulates formation of neuroendocrine phenotype and neuroendocrine prostate tumors. Cancer Cell. 18: 23-38. PMID 20609350 DOI: 10.1016/J.Ccr.2010.05.024  0.56
2010 Gutierrez GJ, Tsuji T, Chen M, Jiang W, Ronai ZA. Interplay between Cdh1 and JNK activity during the cell cycle. Nature Cell Biology. 12: 686-95. PMID 20581839 DOI: 10.1038/Ncb2071  0.56
2010 Gutierrez GJ, Tsuji T, Cross JV, Davis RJ, Templeton DJ, Jiang W, Ronai ZA. JNK-mediated phosphorylation of Cdc25C regulates cell cycle entry and G(2)/M DNA damage checkpoint. The Journal of Biological Chemistry. 285: 14217-28. PMID 20220133 DOI: 10.1074/Jbc.M110.121848  0.56
2010 Calonge TM, Eshaghi M, Liu J, Ronai Z, O'Connell MJ. Transformation/transcription domain-associated protein (TRRAP)-mediated regulation of Wee1. Genetics. 185: 81-93. PMID 20194963 DOI: 10.1534/Genetics.110.114769  0.56
2009 Topisirovic I, Gutierrez GJ, Chen M, Appella E, Borden KL, Ronai ZA. Control of p53 multimerization by Ubc13 is JNK-regulated. Proceedings of the National Academy of Sciences of the United States of America. 106: 12676-81. PMID 19651615 DOI: 10.1073/Pnas.0900596106  0.56
2009 Katiyar S, Liu E, Knutzen CA, Lang ES, Lombardo CR, Sankar S, Toth JI, Petroski MD, Ronai Z, Chiang GG. REDD1, an inhibitor of mTOR signalling, is regulated by the CUL4A-DDB1 ubiquitin ligase Embo Reports. 10: 866-872. PMID 19557001 DOI: 10.1038/Embor.2009.93  0.56
2009 Xiong H, Wang D, Chen L, Choo YS, Ma H, Tang C, Xia K, Jiang W, Ronai Z, Zhuang X, Zhang Z. Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation. The Journal of Clinical Investigation. 119: 650-60. PMID 19229105 DOI: 10.1172/Jci37617  0.56
2009 Möller A, House CM, Wong CS, Scanlon DB, Liu MC, Ronai Z, Bowtell DD. Inhibition of Siah ubiquitin ligase function. Oncogene. 28: 289-96. PMID 18850011 DOI: 10.1038/Onc.2008.382  0.56
2008 Qi J, Nakayama K, Gaitonde S, Goydos JS, Krajewski S, Eroshkin A, Bar-Sagi D, Bowtell D, Ronai Z. The ubiquitin ligase Siah2 regulates tumorigenesis and metastasis by HIF-dependent and -independent pathways. Proceedings of the National Academy of Sciences of the United States of America. 105: 16713-8. PMID 18946040 DOI: 10.1073/Pnas.0804063105  0.56
2008 Bhoumik A, Singha N, O'Connell MJ, Ronai ZA. Regulation of TIP60 by ATF2 modulates ATM activation. The Journal of Biological Chemistry. 283: 17605-14. PMID 18397884 DOI: 10.1074/Jbc.M802030200  0.56
2008 Delaunay A, Bromberg KD, Hayashi Y, Mirabella M, Burch D, Kirkwood B, Serra C, Malicdan MC, Mizisin AP, Morosetti R, Broccolini A, Guo LT, Jones SN, Lira SA, Puri PL, ... ... Ronai Z, et al. The ER-bound RING finger protein 5 (RNF5/RMA1) causes degenerative myopathy in transgenic mice and is deregulated in inclusion body myositis. Plos One. 3: e1609. PMID 18270596 DOI: 10.1371/Journal.Pone.0001609  0.56
2007 Pimienta G, Ficarro SB, Gutierrez GJ, Bhoumik A, Peters EC, Ronai Z, Pascual J. Autophosphorylation properties of inactive and active JNK2. Cell Cycle (Georgetown, Tex.). 6: 1762-71. PMID 17637567 DOI: 10.4161/Cc.6.14.4434  0.56
2007 Mikolajczyk J, Drag M, Békés M, Cao JT, Ronai Z, Salvesen GS. Small ubiquitin-related modifier (SUMO)-specific proteases: profiling the specificities and activities of human SENPs. The Journal of Biological Chemistry. 282: 26217-24. PMID 17591783 DOI: 10.1074/Jbc.M702444200  0.56
2007 Fukushima T, Matsuzawa SI, Kress CL, Bruey JM, Krajewska M, Lefebvre S, Zapata JM, Ronai Z, Reed JC. Ubiquitin-conjugating enzyme Ubc13 is a critical component of TNF receptor-associated factor (TRAF)-mediated inflammatory responses Proceedings of the National Academy of Sciences of the United States of America. 104: 6371-6376. PMID 17404240 DOI: 10.1073/Pnas.0700548104  0.56
2007 Nakayama K, Gazdoiu S, Abraham R, Pan ZQ, Ronai Z. Hypoxia-induced assembly of prolyl hydroxylase PHD3 into complexes: implications for its activity and susceptibility for degradation by the E3 ligase Siah2. The Biochemical Journal. 401: 217-26. PMID 16958618 DOI: 10.1042/Bj20061135  0.56
2006 Laine A, Topisirovic I, Zhai D, Reed JC, Borden KLB, Ronai Z. Regulation of p53 localization and activity by Ubc13 Molecular and Cellular Biology. 26: 8901-8913. PMID 17000756 DOI: 10.1128/Mcb.01156-06  0.56
2006 Gutierrez GJ, Vögtlin A, Castro A, Ferby I, Salvagiotto G, Ronai Z, Lorca T, Nebreda AR. Meiotic regulation of the CDK activator RINGO/Speedy by ubiquitin-proteasome-mediated processing and degradation. Nature Cell Biology. 8: 1084-94. PMID 16964245 DOI: 10.1038/Ncb1472  0.56
2006 Gutierrez GJ, Ronai Z. Ubiquitin and SUMO systems in the regulation of mitotic checkpoints. Trends in Biochemical Sciences. 31: 324-32. PMID 16647857 DOI: 10.1016/J.Tibs.2006.04.001  0.56
2006 Fukushima T, Zapata JM, Singha NC, Thomas M, Kress CL, Krajewska M, Krajewski S, Ronai Z, Reed JC, Matsuzawa SI. Critical function for SIP, a ubiquitin E3 ligase component of the β-catenin degradation pathway, for thymocyte development and G1 checkpoint Immunity. 24: 29-39. PMID 16413921 DOI: 10.1016/J.Immuni.2005.12.002  0.56
2006 Ivanov VN, Ronai Z, Hei TK. Opposite roles of FAP-1 and dynamin in the regulation of Fas (CD95) translocation to the cell surface and susceptibility to Fas ligand-mediated apoptosis. The Journal of Biological Chemistry. 281: 1840-52. PMID 16306044 DOI: 10.1074/Jbc.M509866200  0.36
2005 López-Bergami P, Habelhah H, Bhoumik A, Zhang W, Wang LH, Ronai Z. RACK1 mediates activation of JNK by protein kinase C [corrected]. Molecular Cell. 19: 309-20. PMID 16061178 DOI: 10.1016/J.Molcel.2005.06.025  0.36
2005 Elias B, Laine A, Ronai Z. Phosphorylation of MdmX by CDK2/Cdc2p34 is required for nuclear export of Mdm2 Oncogene. 24: 2574-2579. PMID 15735705 DOI: 10.1038/Sj.Onc.1208488  0.56
2004 Habelhah H, Laine A, Erdjument-Bromage H, Tempst P, Gershwin ME, Bowtell DD, Ronai Z. Regulation of 2-oxoglutarate (alpha-ketoglutarate) dehydrogenase stability by the RING finger ubiquitin ligase Siah. The Journal of Biological Chemistry. 279: 53782-8. PMID 15466852 DOI: 10.1074/jbc.M410315200  0.56
2004 Broday L, Kolotuev I, Didier C, Bhoumik A, Gupta BP, Sternberg PW, Podbilewicz B, Ronai Z. The small ubiquitin-like modifier (SUMO) is required for gonadal and uterine-vulval morphogenesis in Caenorhabditis elegans. Genes & Development. 18: 2380-91. PMID 15466489 DOI: 10.1101/Gad.1227104  0.56
2004 Nakayama K, Frew IJ, Hagensen M, Skals M, Habelhah H, Bhoumik A, Kadoya T, Erdjument-Bromage H, Tempst P, Frappell PB, Bowtell DD, Ronai Z. Siah2 regulates stability of prolyl-hydroxylases, controls HIF1α abundance, and modulates physiological responses to hypoxia Cell. 117: 941-952. PMID 15210114 DOI: 10.1016/J.Cell.2004.06.001  0.56
2004 Mujtaba S, He Y, Zeng L, Yan S, Plotnikova O, Sachchidanand, Sanchez R, Zeleznik-Le NJ, Ronai Z, Zhou MM. Structural mechanism of the bromodomain of the coactivator CBP in p53 transcriptional activation. Molecular Cell. 13: 251-63. PMID 14759370 DOI: 10.1016/S1097-2765(03)00528-8  0.56
2004 Pak BJ, Lee J, Thai BL, Fuchs SY, Shaked Y, Ronai Z, Kerbel RS, Ben-David Y. Radiation resistance of human melanoma analysed by retroviral insertional mutagenesis reveals a possible role for dopachrome tautomerase. Oncogene. 23: 30-8. PMID 14712208 DOI: 10.1038/Sj.Onc.1207007  0.56
2003 Krasilnikov M, Ivanov VN, Dong J, Ronai Z. ERK and PI3K negatively regulate STAT-transcriptional activities in human melanoma cells: implications towards sensitization to apoptosis. Oncogene. 22: 4092-101. PMID 12821943 DOI: 10.1038/sj.onc.1206598  0.36
2003 Ivanov VN, Bhoumik A, Ronai Z. Death receptors and melanoma resistance to apoptosis. Oncogene. 22: 3152-61. PMID 12789291 DOI: 10.1038/sj.onc.1206456  0.36
2003 Ivanov VN, Lopez Bergami P, Maulit G, Sato TA, Sassoon D, Ronai Z. FAP-1 association with Fas (Apo-1) inhibits Fas expression on the cell surface. Molecular and Cellular Biology. 23: 3623-35. PMID 12724420 DOI: 10.1128/MCB.23.10.3623-3635.2003  0.56
2002 Habelhah H, Frew IJ, Laine A, Janes PW, Relaix F, Sassoon D, Bowtell DD, Ronai Z. Stress-induced decrease in TRAF2 stability is mediated by Siah2. The Embo Journal. 21: 5756-65. PMID 12411493 DOI: 10.1093/Emboj/Cdf576  0.56
2002 Zacchi P, Gostissa M, Uchida T, Salvagno C, Avolio F, Volinia S, Ronai Z, Blandino G, Schneider C, Del Sal G. The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults. Nature. 419: 853-7. PMID 12397362 DOI: 10.1038/Nature01120  0.56
2002 Ivanov VN, Krasilnikov M, Ronai Z. Regulation of Fas expression by STAT3 and c-Jun is mediated by phosphatidylinositol 3-kinase-AKT signaling. The Journal of Biological Chemistry. 277: 4932-44. PMID 11733515 DOI: 10.1074/Jbc.M108233200  0.36
2001 Ivanov VN, Bhoumik A, Krasilnikov M, Raz R, Owen-Schaub LB, Levy D, Horvath CM, Ronai Z. Cooperation between STAT3 and c-jun suppresses Fas transcription. Molecular Cell. 7: 517-28. PMID 11463377 DOI: 10.1016/S1097-2765(01)00199-X  0.56
2001 Minamoto T, Buschmann T, Habelhah H, Matusevich E, Tahara H, Boerresen-Dale AL, Harris C, Sidransky D, Ronai Z. Distinct pattern of p53 phosphorylation in human tumors. Oncogene. 20: 3341-3347. PMID 11423984 DOI: 10.1038/Sj.Onc.1204458  0.36
2001 Spiegelman VS, Stavropoulos P, Latres E, Pagano M, Ronai Z, Slaga TJ, Fuchs SY. Induction of β-Transducin Repeat-containing Protein by JNK Signaling and Its Role in the Activation of NF-κB Journal of Biological Chemistry. 276: 27152-27158. PMID 11375388 DOI: 10.1074/Jbc.M100031200  0.56
2001 Maya R, Balass M, Kim ST, Shkedy D, Leal JF, Shifman O, Moas M, Buschmann T, Ronai Z, Shiloh Y, Kastan MB, Katzir E, Oren M. ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage. Genes & Development. 15: 1067-77. PMID 11331603 DOI: 10.1101/Gad.886901  0.56
2001 Buschmann T, Potapova O, Bar-Shira A, Ivanov VN, Fuchs SY, Henderson S, Fried VA, Minamoto T, Alarcon-Vargas D, Pincus MR, Gaarde WA, Holbrook NJ, Shiloh Y, Ronai Z. Jun NH2-terminal kinase phosphorylation of p53 on Thr-81 is important for p53 stabilization and transcriptional activities in response to stress. Molecular and Cellular Biology. 21: 2743-54. PMID 11283254 DOI: 10.1128/MCB.21.8.2743-2754.2001  0.36
2001 Habelhah H, Shah K, Huang L, Burlingame AL, Shokat KM, Ronai Z. Identification of new JNK substrate using ATP pocket mutant JNK and a corresponding ATP analogue. The Journal of Biological Chemistry. 276: 18090-5. PMID 11259409 DOI: 10.1074/Jbc.M011396200  0.36
2001 Habelhah H, Shah K, Huang L, Ostareck-Lederer A, Burlingame AL, Shokat KM, Hentze MW, Ronai Z. ERK phosphorylation drives cytoplasmic accumulation of hnRNP-K and inhibition of mRNA translation. Nature Cell Biology. 3: 325-30. PMID 11231586 DOI: 10.1038/35060131  0.36
2000 Buschmann T, Minamoto T, Wagle N, Fuchs SY, Adler V, Mai M, Ronai Z. Analysis of JNK, Mdm2 and p14(ARF) contribution to the regulation of mutant p53 stability. Journal of Molecular Biology. 295: 1009-21. PMID 10656807 DOI: 10.1006/Jmbi.1999.3387  0.56
2000 Yin Z, Ivanov VN, Habelhah H, Tew K, Ronai Z. Glutathione S-Transferase p Elicits Protection against H2O2-induced Cell Death via Coordinated Regulation of Stress Kinases Cancer Research. 60: 4053-4057. DOI: 10.7916/D8571B9J  0.36
1999 Adler V, Yin Z, Tew KD, Ronai Z. Role of redox potential and reactive oxygen species in stress signaling Oncogene. 18: 6104-6111. PMID 10557101 DOI: 10.1038/Sj.Onc.1203128  0.36
1999 Ivanov VN, Ronai Z. Down-regulation of Tumor Necrosis Factor α Expression by Activating Transcription Factor 2 Increases UVC-Induced Apoptosis of Late-stage Melanoma Cells Journal of Biological Chemistry. 274: 14079-14089. PMID 10318823 DOI: 10.1074/Jbc.274.20.14079  0.36
1999 Adler V, Yin Z, Fuchs SY, Benezra M, Rosario L, Tew KD, Pincus MR, Sardana M, Henderson CJ, Wolf CR, Davis RJ, Ronai Z. Regulation of JNK signaling by GSTp. The Embo Journal. 18: 1321-34. PMID 10064598 DOI: 10.1093/Emboj/18.5.1321  0.36
1999 Krasilnikov M, Adler V, Fuchs SY, Dong Z, Haimovitz-Friedman A, Herlyn M, Ronai Z. Contribution of phosphatidylinositol 3-kinase to radiation resistance in human melanoma cells Molecular Carcinogenesis. 24: 64-69. PMID 10029412 DOI: 10.1002/(Sici)1098-2744(199901)24:1<64::Aid-Mc9>3.0.Co;2-2  0.56
1998 Nankova BB, Fuchs SY, Serova LI, Ronai Z, Wld D, Sabban EL. Selective in vivo stimulation of stress-activated protein kinase in different rat tissues by immobilization stress Stress. 2: 289-298. PMID 9876260 DOI: 10.3109/10253899809167293  0.56
1998 Fuchs SY, Adler V, Buschmann T, Wu X, Ronai Z. Mdm2 association with p53 targets its ubiquitination Oncogene. 17: 2543-2547. PMID 9824166 DOI: 10.1038/Sj.Onc.1202200  0.56
1998 Fuchs SY, Adler V, Buschmann T, Yin Z, Wu X, Jones SN, Ronai Z. JNK targets p53 ubiquitination and degradation in nonstressed cells Genes and Development. 12: 2658-2663. PMID 9732264 DOI: 10.1101/Gad.12.17.2658  0.56
1998 Fuchs SY, Adler V, Pincus MR, Ronai Z. MEKK1/JNK signaling stabilizes and activates p53. Proceedings of the National Academy of Sciences of the United States of America. 95: 10541-6. PMID 9724739 DOI: 10.1073/Pnas.95.18.10541  0.56
1998 Ramaswamy NT, Ronai Z, Pelling JC. Rapid activation of JNK1 in UV-B irradiated epidermal keratinocytes. Oncogene. 16: 1501-5. PMID 9525748 DOI: 10.1038/Sj.Onc.1201628  0.56
1998 Ronai Z, Yang YM, Fuchs SY, Adler V, Sardana M, Herlyn M. ATF2 confers radiation resistance to human melanoma cells Oncogene. 16: 523-531. PMID 9484842 DOI: 10.1038/Sj.Onc.1201566  0.56
1997 Fuchs SY, Xie B, Adler V, Fried VA, Davis RJ, Ronai Z. C-jun NH2-terminal kinases target the ubiquitination of their associated transcription factors Journal of Biological Chemistry. 272: 32163-32168. PMID 9405416 DOI: 10.1074/Jbc.272.51.32163  0.56
1997 Xie S, Price JE, Luca M, Jean D, Ronai Z, Bar-Eli M. Dominant-negative CREB inhibits tumor growth and metastasis of human melanoma cells. Oncogene. 15: 2069-75. PMID 9366524 DOI: 10.1038/Sj.Onc.1201358  0.56
1996 Adler V, Dolan LR, Kim J, Pincus M, Carl Barrett J, Ronai Z. Changes in jun N-terminal kinase activation by stress during aging of cultured normal human fibroblasts Molecular Carcinogenesis. 17: 8-12. PMID 8876670 DOI: 10.1002/(Sici)1098-2744(199609)17:1<8::Aid-Mc2>3.0.Co;2-F  0.56
1996 Adler V, Polotskaya A, Kim J, Dolan L, Davis R, Pincus M, Ronai Z. Dose rate and mode of exposure are key factors in JNK activation by UV irradiation Carcinogenesis. 17: 2073-2076. PMID 8824537 DOI: 10.1093/Carcin/17.9.2073  0.56
1996 Adler V, Pincus MR, Posner S, Upadhyaya P, El-Bayoumy K, Ronai Z. Effects of chemopreventive selenium compounds on Jun N-kinase activities. Carcinogenesis. 17: 1849-54. PMID 8824505 DOI: 10.1093/Carcin/17.9.1849  0.56
1996 Adler V, Pincus MR, Polotskaya A, Montano X, Friedman FK, Ronai Z. Activation of c-Jun-NH2-kinase by UV irradiation is dependent on p21(ras) Journal of Biological Chemistry. 271: 23304-23309. PMID 8798530 DOI: 10.1074/Jbc.271.38.23304  0.56
1995 Adler V, Schaffer A, Kim J, Dolan L, Ronai Z. UV irradiation and heat shock mediate JNK activation via alternate pathways Journal of Biological Chemistry. 270: 26071-26077. PMID 7592807 DOI: 10.1074/Jbc.270.44.26071  0.56
1995 Adler V, Pincus MR, Brandt-Rauf PW, Ronai Z. Complexes of p21RAS with JUN N-terminal kinase and JUN proteins Proceedings of the National Academy of Sciences of the United States of America. 92: 10585-10589. PMID 7479845 DOI: 10.1073/Pnas.92.23.10585  0.56
1994 Tillotson JK, Upadhyaya P, Ronai Z. Inhibition of thymidine kinase in cultured mammary tumor cells by the chemopreventive organoselenium compound, 1,4-phenylenebis(methylene)selenocyanate Carcinogenesis. 15: 607-610. PMID 8149469 DOI: 10.1093/Carcin/15.4.607  0.56
1993 Lee G, Delohery TM, Ronai Z, Brandt-Rauf PW, Pincus MR, Murphy RB, Weinstein IB. A comparison of techniques for introducing macromolecules into living cells. Cytometry. 14: 265-70. PMID 7682492 DOI: 10.1002/Cyto.990140305  0.56
1992 Chung DL, Joran A, Friedman F, Robinson R, Brandt-Rauf PW, Weinstein IB, Ronai Z, Baskin L, Dykes DC, Murphy RB. Evidence that oocyte maturation induced by an oncogenic ras-p21 protein and insulin is mediated by overlapping yet distinct mechanisms. Experimental Cell Research. 203: 329-35. PMID 1459198 DOI: 10.1016/0014-4827(92)90006-T  0.56
1992 Foiles PG, Peterson LA, Miglietta LM, Ronai Z. Analysis of mutagenic activity and ability to induce replication of polyoma DNA sequences by different model metabolites of the carcinogenic tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. Mutation Research. 279: 91-101. PMID 1375343 DOI: 10.1016/0165-1218(92)90250-4  0.56
1989 Lee G, Ronai ZA, Pincus MR, Brandt-Rauf PW, Murphy RB, Delohery TM, Nishimura S, Yamaizumi Z, Weinstein IB. Identification of an intracellular protein that specifically interacts with photoaffinity-labeled oncogenic p21 protein. Proceedings of the National Academy of Sciences of the United States of America. 86: 8678-82. PMID 2682656 DOI: 10.1073/Pnas.86.22.8678  0.56
1989 Lambert ME, Ronai ZA, Weinstein IB, Garrels JI. Enhancement of major histocompatibility class I protein synthesis by DNA damage in cultured human fibroblasts and keratinocytes. Molecular and Cellular Biology. 9: 847-50. PMID 2469006 DOI: 10.1128/MCB.9.2.847  0.56
1988 Ronai ZA, Weinstein IB. Identification of a UV-induced trans-acting protein that stimulates polyomavirus DNA replication. Journal of Virology. 62: 1057-60. PMID 2828653 DOI: 10.1128/jvi.62.3.1057-1060.1988  0.56
1988 Yang XY, Ronai ZA, Santella RM, Weinstein IB. Effects of 8-methoxypsoralen and ultraviolet light A on EGF receptor (HER-1) expression. Biochemical and Biophysical Research Communications. 157: 590-6. PMID 2462418 DOI: 10.1016/S0006-291X(88)80291-2  0.56
1986 Ronai Z, Shaham J, Stein J, Sulitzeanu D. Serial circulating immune complex values and development of metastatic disease in breast cancer and malignant melanoma patients Cancer Immunology Immunotherapy. 22: 72-75. PMID 3518930 DOI: 10.1007/Bf00205720  0.56
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