Michael J. Caplan - Publications

Affiliations: 
Cellular and Molecular Physiology Yale University, New Haven, CT 

135 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 He M, Wu B, Ye W, Le DD, Sinclair AW, Padovano V, Chen Y, Li KX, Sit R, Tan M, Caplan MJ, Neff N, Jan YN, Darmanis S, Jan LY. Chloride channels regulate differentiation and barrier functions of the mammalian airway. Elife. 9. PMID 32286221 DOI: 10.7554/Elife.53085  0.3
2020 Padovano V, Mistry K, Merrick D, Gresko N, Caplan MJ. A cut above (and below): Protein cleavage in the regulation of polycystin trafficking and signaling. Cellular Signalling. 72: 109634. PMID 32283256 DOI: 10.1016/J.Cellsig.2020.109634  0.799
2020 Wu J, Rowart P, Jouret F, Gassaway BM, Rajendran V, Rinehart J, Caplan MJ. Mechanisms involved in AMPK-mediated deposition of tight junction components to the plasma membrane. American Journal of Physiology. Cell Physiology. PMID 31913699 DOI: 10.1152/Ajpcell.00422.2019  0.39
2019 Caplan MJ. Holding open the door reveals a new view of polycystin channel function. Embo Reports. e49156. PMID 31556469 DOI: 10.15252/Embr.201949156  0.301
2018 Merrick D, Mistry K, Wu J, Gresko N, Baggs JE, Hogenesch JB, Sun Z, Caplan MJ. Polycystin-1 regulates bone development through an interaction with the transcriptional co-activator taz. Human Molecular Genetics. PMID 30215740 DOI: 10.1093/Hmg/Ddy322  0.782
2018 Gilder AL, Chapin HC, Padovano V, Hueschen CL, Rajendran V, Caplan MJ. Newly Synthesized Polycystin 1 Takes Different Trafficking Pathways to the Apical and Ciliary Membranes. Traffic (Copenhagen, Denmark). PMID 30125442 DOI: 10.1111/Tra.12612  0.818
2018 Padovano V, Podrini C, Boletta A, Caplan MJ. Metabolism and mitochondria in polycystic kidney disease research and therapy. Nature Reviews. Nephrology. PMID 30120380 DOI: 10.1038/S41581-018-0051-1  0.358
2018 Rowart P, Wu J, Caplan MJ, Jouret F. Implications of AMPK in the Formation of Epithelial Tight Junctions. International Journal of Molecular Sciences. 19. PMID 30011834 DOI: 10.3390/Ijms19072040  0.416
2017 Matlin KS, Caplan MJ. The secretory pathway at 50: a golden anniversary for some momentous grains of silver. Molecular Biology of the Cell. 28: 229-232. PMID 28082520 DOI: 10.1091/Mbc.E16-07-0508  0.375
2016 Padovano V, Kuo IY, Stavola LK, Aerni HR, Flaherty BJ, Chapin HC, Ma M, Somlo S, Boletta A, Ehrlich BE, Rinehart J, Caplan MJ. The polycystins are modulated by cellular oxygen sensing pathways and regulate mitochondrial function. Molecular Biology of the Cell. PMID 27881662 DOI: 10.1091/Mbc.E16-08-0597  0.786
2016 Stoops EH, Hull M, Caplan MJ. Newly synthesized and recycling pools of the apical protein gp135 do not occupy the same compartments. Traffic (Copenhagen, Denmark). PMID 27649479 DOI: 10.1111/Tra.12449  0.804
2016 Caplan MJ. The Tail of Polycystin-1 Pays the Kidney a Complement. American Journal of Physiology. Renal Physiology. ajprenal.00141.2016. PMID 27009337 DOI: 10.1152/Ajprenal.00141.2016  0.303
2015 Stoops EH, Hull M, Olesen C, Mistry K, Harder JL, Rivera-Molina F, Toomre D, Caplan MJ. The periciliary ring in polarized epithelial cells is a hot spot for delivery of the apical protein gp135. The Journal of Cell Biology. 211: 287-94. PMID 26504168 DOI: 10.1083/Jcb.201502045  0.807
2015 Farr GA, Hull M, Stoops EH, Bateson R, Caplan MJ. Dual Pulse Chase Microscopy Reveals Early Divergence in the Biosynthetic Trafficking of the Na, K-ATPase and E-cadherin. Molecular Biology of the Cell. PMID 26424804 DOI: 10.1091/Mbc.E14-09-1385  0.822
2015 Alves DS, Thulin G, Loffing J, Kashgarian M, Caplan MJ. Akt Substrate of 160 kD Regulates Na+,K+-ATPase Trafficking in Response to Energy Depletion and Renal Ischemia. Journal of the American Society of Nephrology : Jasn. 26: 2765-76. PMID 25788531 DOI: 10.1681/Asn.2013101040  0.444
2015 Hatano R, Akiyama K, Tamura A, Hosogi S, Marunaka Y, Caplan MJ, Ueno Y, Tsukita S, Asano S. Knockdown of ezrin causes intrahepatic cholestasis by the dysregulation of bile fluidity in the bile duct epithelium in mice. Hepatology (Baltimore, Md.). 61: 1660-71. PMID 25311759 DOI: 10.1002/Hep.27565  0.414
2015 Stoops EH, Hull M, Olesen C, Mistry K, Harder JL, Rivera-Molina F, Toomre D, Caplan MJ. The periciliary ring in polarized epithelial cells is a hot spot for delivery of the apical protein gp135 The Journal of General Physiology. 146. DOI: 10.1085/Jgp.1466Oia69  0.796
2014 Stoops EH, Farr GA, Hull M, Caplan MJ. SNAP-tag to monitor trafficking of membrane proteins in polarized epithelial cells. Methods in Molecular Biology (Clifton, N.J.). 1174: 171-82. PMID 24947381 DOI: 10.1007/978-1-4939-0944-5_11  0.806
2014 Stoops EH, Caplan MJ. Trafficking to the apical and basolateral membranes in polarized epithelial cells. Journal of the American Society of Nephrology : Jasn. 25: 1375-86. PMID 24652803 DOI: 10.1681/Asn.2013080883  0.835
2014 Merrick D, Bertuccio CA, Chapin HC, Lal M, Chauvet V, Caplan MJ. Polycystin-1 cleavage and the regulation of transcriptional pathways. Pediatric Nephrology (Berlin, Germany). 29: 505-11. PMID 23824180 DOI: 10.1007/S00467-013-2548-Y  0.779
2013 Jouret F, Wu J, Hull M, Rajendran V, Mayr B, Schöfl C, Geibel J, Caplan MJ. Activation of the Ca²+-sensing receptor induces deposition of tight junction components to the epithelial cell plasma membrane. Journal of Cell Science. 126: 5132-42. PMID 24013548 DOI: 10.1242/Jcs.127555  0.416
2013 Caplan MJ. An inversin convergence. Focus on "Inversin modulates the cortical actin network during mitosis". American Journal of Physiology. Cell Physiology. 305: C22-3. PMID 23677797 DOI: 10.1152/Ajpcell.00126.2013  0.324
2013 Wells EK, Yarborough O, Lifton RP, Cantley LG, Caplan MJ. Epithelial morphogenesis of MDCK cells in three-dimensional collagen culture is modulated by interleukin-8. American Journal of Physiology. Cell Physiology. 304: C966-75. PMID 23485708 DOI: 10.1152/Ajpcell.00261.2012  0.773
2012 Takiar V, Mistry K, Carmosino M, Schaeren-Wiemers N, Caplan MJ. VIP17/MAL expression modulates epithelial cyst formation and ciliogenesis. American Journal of Physiology. Cell Physiology. 303: C862-71. PMID 22895261 DOI: 10.1152/Ajpcell.00338.2011  0.653
2012 Merrick D, Chapin H, Baggs JE, Yu Z, Somlo S, Sun Z, Hogenesch JB, Caplan MJ. The γ-secretase cleavage product of polycystin-1 regulates TCF and CHOP-mediated transcriptional activation through a p300-dependent mechanism. Developmental Cell. 22: 197-210. PMID 22178500 DOI: 10.1016/J.Devcel.2011.10.028  0.782
2011 Kimura T, Han W, Pagel P, Nairn AC, Caplan MJ. Protein phosphatase 2A interacts with the Na,K-ATPase and modulates its trafficking by inhibition of its association with arrestin. Plos One. 6: e29269. PMID 22242112 DOI: 10.1371/Journal.Pone.0029269  0.425
2011 Bian S, Bai JP, Chapin H, Le Moellic C, Dong H, Caplan M, Sigworth FJ, Navaratnam DS. Interactions between β-catenin and the HSlo potassium channel regulates HSlo surface expression. Plos One. 6: e28264. PMID 22194818 DOI: 10.1371/Journal.Pone.0028264  0.787
2011 Karihaloo A, Koraishy F, Huen SC, Lee Y, Merrick D, Caplan MJ, Somlo S, Cantley LG. Macrophages promote cyst growth in polycystic kidney disease. Journal of the American Society of Nephrology : Jasn. 22: 1809-14. PMID 21921140 DOI: 10.1681/Asn.2011010084  0.787
2011 Seo-Mayer PW, Thulin G, Zhang L, Alves DS, Ardito T, Kashgarian M, Caplan MJ. Preactivation of AMPK by metformin may ameliorate the epithelial cell damage caused by renal ischemia. American Journal of Physiology. Renal Physiology. 301: F1346-57. PMID 21849490 DOI: 10.1152/Ajprenal.00420.2010  0.444
2011 Choi YH, Suzuki A, Hajarnis S, Ma Z, Chapin HC, Caplan MJ, Pontoglio M, Somlo S, Igarashi P. Polycystin-2 and phosphodiesterase 4C are components of a ciliary A-kinase anchoring protein complex that is disrupted in cystic kidney diseases. Proceedings of the National Academy of Sciences of the United States of America. 108: 10679-84. PMID 21670265 DOI: 10.1073/Pnas.1016214108  0.804
2011 Pluznick JL, Rodriguez-Gil DJ, Hull M, Mistry K, Gattone V, Johnson CA, Weatherbee S, Greer CA, Caplan MJ. Renal cystic disease proteins play critical roles in the organization of the olfactory epithelium. Plos One. 6: e19694. PMID 21614130 DOI: 10.1371/Journal.Pone.0019694  0.367
2011 Zhang L, Jouret F, Rinehart J, Sfakianos J, Mellman I, Lifton RP, Young LH, Caplan MJ. AMP-activated protein kinase (AMPK) activation and glycogen synthase kinase-3β (GSK-3β) inhibition induce Ca2+-independent deposition of tight junction components at the plasma membrane. The Journal of Biological Chemistry. 286: 16879-90. PMID 21383016 DOI: 10.1074/Jbc.M110.186932  0.33
2011 Lal M, Caplan M. Regulated intramembrane proteolysis: signaling pathways and biological functions. Physiology (Bethesda, Md.). 26: 34-44. PMID 21357901 DOI: 10.1152/Physiol.00028.2010  0.32
2011 Takiar V, Nishio S, Seo-Mayer P, King JD, Li H, Zhang L, Karihaloo A, Hallows KR, Somlo S, Caplan MJ. Activating AMP-activated protein kinase (AMPK) slows renal cystogenesis. Proceedings of the National Academy of Sciences of the United States of America. 108: 2462-7. PMID 21262823 DOI: 10.1073/Pnas.1011498108  0.637
2011 Takiar V, Caplan MJ. Polycystic kidney disease: pathogenesis and potential therapies. Biochimica Et Biophysica Acta. 1812: 1337-43. PMID 21146605 DOI: 10.1016/J.Bbadis.2010.11.014  0.601
2011 Caplan MJ, Rodriguez‐Boulan E. Epithelial Cell Polarity: Challenges and Methodologies Comprehensive Physiology. 665-688. DOI: 10.1002/Cphy.Cp140117  0.398
2010 Chapin HC, Caplan MJ. The cell biology of polycystic kidney disease. The Journal of Cell Biology. 191: 701-10. PMID 21079243 DOI: 10.1083/Jcb.201006173  0.79
2010 Chapin HC, Rajendran V, Caplan MJ. Polycystin-1 surface localization is stimulated by polycystin-2 and cleavage at the G protein-coupled receptor proteolytic site. Molecular Biology of the Cell. 21: 4338-48. PMID 20980620 DOI: 10.1091/Mbc.E10-05-0407  0.799
2010 Alves DS, Farr GA, Seo-Mayer P, Caplan MJ. AS160 associates with the Na+,K+-ATPase and mediates the adenosine monophosphate-stimulated protein kinase-dependent regulation of sodium pump surface expression. Molecular Biology of the Cell. 21: 4400-8. PMID 20943949 DOI: 10.1091/Mbc.E10-06-0507  0.461
2010 Carmosino M, Rizzo F, Procino G, Basco D, Valenti G, Forbush B, Schaeren-Wiemers N, Caplan MJ, Svelto M. MAL/VIP17, a new player in the regulation of NKCC2 in the kidney. Molecular Biology of the Cell. 21: 3985-97. PMID 20861303 DOI: 10.1091/Mbc.E10-05-0456  0.478
2010 Tang XX, Chen H, Yu S, Zhang L, Caplan MJ, Chan HC. Lymphocytes accelerate epithelial tight junction assembly: role of AMP-activated protein kinase (AMPK). Plos One. 5: e12343. PMID 20808811 DOI: 10.1371/Journal.Pone.0012343  0.393
2010 Morton MJ, Farr GA, Hull M, Capendeguy O, Horisberger JD, Caplan MJ. Association with {beta}-COP regulates the trafficking of the newly synthesized Na,K-ATPase. The Journal of Biological Chemistry. 285: 33737-46. PMID 20801885 DOI: 10.1074/Jbc.M110.141119  0.362
2010 Takiar V, Caplan MJ. Telling kidneys to cease and decyst. Nature Medicine. 16: 751-2. PMID 20613749 DOI: 10.1038/Nm0710-751  0.576
2010 Farr G, Santana Alves D, Stoops E, Hull M, Caplan M. Visualizing Protein Trafficking: Membrane Proteins Follow Multiple Trafficking Pathways to the Basolateral Cell Surface in Polarized Epithelial Cells Microscopy and Microanalysis. 16: 958-959. DOI: 10.1017/S1431927610053560  0.811
2009 Chapin HC, Rajendran V, Capasso A, Caplan MJ. Detecting the surface localization and cytoplasmic cleavage of membrane-bound proteins. Methods in Cell Biology. 94: 223-39. PMID 20362093 DOI: 10.1016/S0091-679X(08)94011-5  0.807
2009 Lin DH, Yue P, Pan CY, Sun P, Zhang X, Han Z, Roos M, Caplan M, Giebisch G, Wang WH. POSH stimulates the ubiquitination and the clathrin-independent endocytosis of ROMK1 channels. The Journal of Biological Chemistry. 284: 29614-24. PMID 19710010 DOI: 10.1074/Jbc.M109.041582  0.349
2009 Farr GA, Hull M, Mellman I, Caplan MJ. Membrane proteins follow multiple pathways to the basolateral cell surface in polarized epithelial cells. The Journal of Cell Biology. 186: 269-82. PMID 19620635 DOI: 10.1083/Jcb.200901021  0.489
2009 Bertuccio CA, Chapin HC, Cai Y, Mistry K, Chauvet V, Somlo S, Caplan MJ. Polycystin-1 C-terminal cleavage is modulated by polycystin-2 expression. The Journal of Biological Chemistry. 284: 21011-26. PMID 19491093 DOI: 10.1074/Jbc.M109.017756  0.788
2009 Cartiera MS, Johnson KM, Rajendran V, Caplan MJ, Saltzman WM. The uptake and intracellular fate of PLGA nanoparticles in epithelial cells. Biomaterials. 30: 2790-8. PMID 19232712 DOI: 10.1016/J.Biomaterials.2009.01.057  0.343
2009 Pluznick JL, Zou DJ, Zhang X, Yan Q, Rodriguez-Gil DJ, Eisner C, Wells E, Greer CA, Wang T, Firestein S, Schnermann J, Caplan MJ. Functional expression of the olfactory signaling system in the kidney. Proceedings of the National Academy of Sciences of the United States of America. 106: 2059-64. PMID 19174512 DOI: 10.1073/Pnas.0812859106  0.784
2008 Duffield A, Caplan MJ, Muth TR. Protein trafficking in polarized cells. International Review of Cell and Molecular Biology. 270: 145-79. PMID 19081536 DOI: 10.1016/S1937-6448(08)01404-4  0.814
2008 Caplan MJ, Seo-Mayer P, Zhang L. Epithelial junctions and polarity: complexes and kinases. Current Opinion in Nephrology and Hypertension. 17: 506-12. PMID 18695392 DOI: 10.1097/Mnh.0B013E32830Baaae  0.402
2008 Carmosino M, Giménez I, Caplan M, Forbush B. Exon loss accounts for differential sorting of Na-K-Cl cotransporters in polarized epithelial cells. Molecular Biology of the Cell. 19: 4341-51. PMID 18667527 DOI: 10.1091/mbc.E08-05-0478  0.3
2008 Lal M, Song X, Pluznick JL, Di Giovanni V, Merrick DM, Rosenblum ND, Chauvet V, Gottardi CJ, Pei Y, Caplan MJ. Polycystin-1 C-terminal tail associates with beta-catenin and inhibits canonical Wnt signaling. Human Molecular Genetics. 17: 3105-17. PMID 18632682 DOI: 10.1093/Hmg/Ddn208  0.779
2008 Lin D, Kamsteeg EJ, Zhang Y, Jin Y, Sterling H, Yue P, Roos M, Duffield A, Spencer J, Caplan M, Wang WH. Expression of tetraspan protein CD63 activates protein-tyrosine kinase (PTK) and enhances the PTK-induced inhibition of ROMK channels. The Journal of Biological Chemistry. 283: 7674-81. PMID 18211905 DOI: 10.1074/Jbc.M705574200  0.564
2007 Kamsteeg EJ, Duffield AS, Konings IB, Spencer J, Pagel P, Deen PM, Caplan MJ. MAL decreases the internalization of the aquaporin-2 water channel. Proceedings of the National Academy of Sciences of the United States of America. 104: 16696-701. PMID 17940053 DOI: 10.1073/Pnas.0708023104  0.695
2007 Kimura T, Allen PB, Nairn AC, Caplan MJ. Arrestins and spinophilin competitively regulate Na+,K+-ATPase trafficking through association with a large cytoplasmic loop of the Na+,K+-ATPase. Molecular Biology of the Cell. 18: 4508-18. PMID 17804821 DOI: 10.1091/Mbc.E06-08-0711  0.427
2007 Zhang L, Caplan MJ. Transport protein sorting in polarized epithelial cells. Sheng Li Xue Bao : [Acta Physiologica Sinica]. 59: 505-11. PMID 17700970  0.376
2007 Caplan MJ. The future of the pump. Journal of Clinical Gastroenterology. 41: S217-22. PMID 17575526 DOI: 10.1097/Mcg.0B013E31803233Da  0.396
2007 Caplan MJ, Kamsteeg EJ, Duffield A. Tetraspan proteins: regulators of renal structure and function. Current Opinion in Nephrology and Hypertension. 16: 353-8. PMID 17565278 DOI: 10.1097/Mnh.0B013E328177B1Fa  0.67
2007 Pluznick JL, Zhang X, Zou D, Yan Q, Wells E, Wang T, Firestein S, Caplan MJ. Functional Expression of Key Components of the Olfactory Receptor Signaling Pathway in the Distal Nephron The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A500  0.765
2006 Zhang L, Li J, Young LH, Caplan MJ. AMP-activated protein kinase regulates the assembly of epithelial tight junctions. Proceedings of the National Academy of Sciences of the United States of America. 103: 17272-7. PMID 17088526 DOI: 10.1073/Pnas.0608531103  0.364
2006 Lerner M, Lemke D, Bertram H, Schillers H, Oberleithner H, Caplan MJ, Reinhardt J. An extracellular loop of the human non-gastric H,K-ATPase alpha-subunit is involved in apical plasma membrane polarization. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 18: 75-84. PMID 16914892 DOI: 10.1159/000095169  0.439
2006 Lu M, Leng Q, Egan ME, Caplan MJ, Boulpaep EL, Giebisch GH, Hebert SC. CFTR is required for PKA-regulated ATP sensitivity of Kir1.1 potassium channels in mouse kidney. The Journal of Clinical Investigation. 116: 797-807. PMID 16470247 DOI: 10.1172/Jci26961  0.406
2006 Grimm DH, Karihaloo A, Cai Y, Somlo S, Cantley LG, Caplan MJ. Polycystin-2 regulates proliferation and branching morphogenesis in kidney epithelial cells. The Journal of Biological Chemistry. 281: 137-44. PMID 16278216 DOI: 10.1074/Jbc.M507845200  0.677
2005 Zatti A, Chauvet V, Rajendran V, Kimura T, Pagel P, Caplan MJ. The C-terminal tail of the polycystin-1 protein interacts with the Na,K-ATPase alpha-subunit. Molecular Biology of the Cell. 16: 5087-93. PMID 16107561 DOI: 10.1091/Mbc.E05-03-0200  0.461
2005 Chauvet V, Tian X, Husson H, Grimm DH, Wang T, Hieseberger T, Igarashi P, Bennett AM, Ibraghimov-Beskrovnaya O, Somlo S, Caplan MJ. Erratum: Mechanical stimuli induce cleavage and nuclear translocation of the polycystin-1 C terminus (Journal of Clinical Investigation (2004) 114 (1433-1443) DOI: 10.1172/JCI200421753) Journal of Clinical Investigation. 115. DOI: 10.1172/Jci200521753C1  0.563
2004 Chauvet V, Tian X, Husson H, Grimm DH, Wang T, Hieseberger T, Igarashi P, Bennett AM, Ibraghimov-Beskrovnaya O, Somlo S, Caplan MJ. Mechanical stimuli induce cleavage and nuclear translocation of the polycystin-1 C terminus Journal of Clinical Investigation. 114: 1433-1443. PMID 15545994 DOI: 10.1172/Jci21753  0.617
2004 Nguyen NV, Gleeson PA, Courtois-Coutry N, Caplan MJ, Van Driel IR. Gastric parietal cell acid secretion in mice can be regulated independently of H/K ATPase endocytosis. Gastroenterology. 127: 145-54. PMID 15236181 DOI: 10.1053/J.Gastro.2004.04.016  0.419
2004 Duffield A, Fölsch H, Mellman I, Caplan MJ. Sorting of H,K-ATPase beta-subunit in MDCK and LLC-PK cells is independent of mu 1B adaptin expression. Traffic (Copenhagen, Denmark). 5: 449-61. PMID 15117319 DOI: 10.1111/J.1398-9219.2004.00192.X  0.646
2004 Egan ME, Pearson M, Weiner SA, Rajendran V, Rubin D, Glöckner-Pagel J, Canny S, Du K, Lukacs GL, Caplan MJ. Curcumin, a major constituent of turmeric, corrects cystic fibrosis defects. Science (New York, N.Y.). 304: 600-2. PMID 15105504 DOI: 10.1126/Science.1093941  0.349
2003 Brown A, Muth T, Caplan M. The COOH-terminal tail of the GAT-2 GABA transporter contains a novel motif that plays a role in basolateral targeting. American Journal of Physiology. Cell Physiology. 286: C1071-7. PMID 15075206 DOI: 10.1152/Ajpcell.00291.2003  0.738
2003 Duffield A, Kamsteeg EJ, Brown AN, Pagel P, Caplan MJ. The tetraspanin CD63 enhances the internalization of the H,K-ATPase beta-subunit. Proceedings of the National Academy of Sciences of the United States of America. 100: 15560-5. PMID 14660791 DOI: 10.1073/Pnas.2536699100  0.625
2003 Muth TR, Caplan MJ. Transport protein trafficking in polarized cells. Annual Review of Cell and Developmental Biology. 19: 333-66. PMID 14570573 DOI: 10.1146/Annurev.Cellbio.19.110701.161425  0.768
2003 Grimm DH, Cai Y, Chauvet V, Rajendran V, Zeltner R, Geng L, Avner ED, Sweeney W, Somlo S, Caplan MJ. Polycystin-1 distribution is modulated by polycystin-2 expression in mammalian cells. The Journal of Biological Chemistry. 278: 36786-93. PMID 12840011 DOI: 10.1074/Jbc.M306536200  0.66
2003 Pagel P, Zatti A, Kimura T, Duffield A, Chauvet V, Rajendran V, Caplan MJ. Ion pump-interacting proteins: promising new partners. Annals of the New York Academy of Sciences. 986: 360-8. PMID 12763851 DOI: 10.1111/J.1749-6632.2003.Tb07215.X  0.672
2002 Mense M, Rajendran V, Blostein R, Caplan MJ. Extracellular domains, transmembrane segments, and intracellular domains interact to determine the cation selectivity of Na,K- and gastric H,K-ATPase. Biochemistry. 41: 9803-12. PMID 12146946 DOI: 10.1021/Bi025819Z  0.759
2002 Egan ME, Glöckner-Pagel J, Ambrose C, Cahill PA, Pappoe L, Balamuth N, Cho E, Canny S, Wagner CA, Geibel J, Caplan MJ. Calcium-pump inhibitors induce functional surface expression of Delta F508-CFTR protein in cystic fibrosis epithelial cells. Nature Medicine. 8: 485-92. PMID 11984593 DOI: 10.1038/Nm0502-485  0.333
2002 Deen PM, Van Balkom BW, Savelkoul PJ, Kamsteeg EJ, Van Raak M, Jennings ML, Muth TR, Rajendran V, Caplan MJ. Aquaporin-2: COOH terminus is necessary but not sufficient for routing to the apical membrane. American Journal of Physiology. Renal Physiology. 282: F330-40. PMID 11788448 DOI: 10.1152/Ajprenal.0168.2001  0.742
2001 Gu HH, Wu X, Giros B, Caron MG, Caplan MJ, Rudnick G. The NH(2)-terminus of norepinephrine transporter contains a basolateral localization signal for epithelial cells. Molecular Biology of the Cell. 12: 3797-807. PMID 11739781 DOI: 10.1091/Mbc.12.12.3797  0.392
2001 Caplan MJ. Ion pump sorting in polarized renal epithelial cells Kidney International. 60: 427-430. PMID 11473621 DOI: 10.1046/J.1523-1755.2001.060002427.X  0.437
2001 Dunbar LA, Caplan MJ. Ion pumps in polarized cells: sorting and regulation of the Na+, K+- and H+, K+-ATPases. The Journal of Biological Chemistry. 276: 29617-20. PMID 11404365 DOI: 10.1074/Jbc.R100023200  0.801
2001 McCarthy JB, Lim ST, Elkind NB, Trimmer JS, Duvoisin RM, Rodriguez-Boulan E, Caplan MJ. The C-terminal tail of the metabotropic glutamate receptor subtype 7 is necessary but not sufficient for cell surface delivery and polarized targeting in neurons and epithelia. The Journal of Biological Chemistry. 276: 9133-40. PMID 11106656 DOI: 10.1074/Jbc.M008290200  0.378
2000 Dunbar LA, Caplan MJ. The cell biology of ion pumps: sorting and regulation. European Journal of Cell Biology. 79: 557-63. PMID 11001492 DOI: 10.1078/0171-9335-00079  0.794
2000 Reinhardt J, Grishin AV, Oberleithner H, Caplan MJ. Differential localization of human nongastric H(+)-K(+)-ATPase ATP1AL1 in polarized renal epithelial cells. American Journal of Physiology. Renal Physiology. 279: F417-25. PMID 10966921 DOI: 10.1152/Ajprenal.2000.279.3.F417  0.478
2000 Dunbar LA, Aronson P, Caplan MJ. A transmembrane segment determines the steady-state localization of an ion-transporting adenosine triphosphatase. The Journal of Cell Biology. 148: 769-78. PMID 10684257 DOI: 10.1083/Jcb.148.4.769  0.796
2000 Mense M, Dunbar LA, Blostein R, Caplan MJ. Residues of the fourth transmembrane segments of the Na,K-ATPase and the gastric H,K-ATPase contribute to cation selectivity. The Journal of Biological Chemistry. 275: 1749-56. PMID 10636871 DOI: 10.1074/Jbc.275.3.1749  0.8
1999 Grishin AV, Reinhard J, Dunbar LA, Courtois-Coutry N, Wang T, Giebisch G, Caplan MJ. Nongastric H+,K+-ATPase: cell biologic and functional properties. Seminars in Nephrology. 19: 421-30. PMID 10511382  0.773
1999 Blostein R, Dunbar L, Mense M, Scanzano R, Wilczynska A, Caplan MJ. Cation selectivity of gastric H,K-ATPase and Na,K-ATPase chimeras. The Journal of Biological Chemistry. 274: 18374-81. PMID 10373442 DOI: 10.1074/Jbc.274.26.18374  0.795
1998 Wang T, Courtois-Coutry N, Giebisch G, Caplan MJ. A tyrosine-based signal regulates H-K-ATPase-mediated potassium reabsorption in the kidney. American Journal of Physiology. Renal Physiology. 275: F818-F826. PMID 29586390 DOI: 10.1152/Ajprenal.1998.275.5.F818  0.401
1998 Li D, Cheng SXJ, Fisone G, Caplan MJ, Ohtomo Y, Aperia A. Effects of okadaic acid, calyculin A, and PDBu on state of phosphorylation of rat renal Na-K-ATPase. American Journal of Physiology. Renal Physiology. 275: F863-F869. PMID 29585365 DOI: 10.1152/Ajprenal.1998.275.6.F863  0.387
1998 Dunbar LA, Courtois-Coutry N, Roush DL, Muth TR, Gottardi CJ, Rajendran V, Geibel J, Kashgarian M, Caplan MJ. Sorting of P-type ATPases in polarized epithelial cells Acta Physiologica Scandinavica, Supplement. 163: 289-295. PMID 9789572  0.818
1998 Ahn J, Pietrini G, Muth TR, Caplan MJ. Expression of neurotransmitter transport systems in polarized cells. Methods in Enzymology. 296: 370-88. PMID 9779461 DOI: 10.1016/S0076-6879(98)96027-X  0.756
1998 Grishin AV, Caplan MJ. ATP1AL1, a member of the non-gastric H,K-ATPase family, functions as a sodium pump. The Journal of Biological Chemistry. 273: 27772-8. PMID 9774385 DOI: 10.1074/Jbc.273.43.27772  0.428
1998 Roush DL, Gottardi CJ, Naim HY, Roth MG, Caplan MJ. Tyrosine-based membrane protein sorting signals are differentially interpreted by polarized Madin-Darby canine kidney and LLC-PK1 epithelial cells Journal of Biological Chemistry. 273: 26862-26869. PMID 9756932 DOI: 10.1074/Jbc.273.41.26862  0.709
1998 Muth TR, Ahn J, Caplan MJ. Identification of sorting determinants in the C-terminal cytoplasmic tails of the gamma-aminobutyric acid transporters GAT-2 and GAT-3. The Journal of Biological Chemistry. 273: 25616-27. PMID 9748227 DOI: 10.1074/Jbc.273.40.25616  0.765
1998 Caplan MJ. Gastric H+/K(+)-ATPase: targeting signals in the regulation of physiologic function. Current Opinion in Cell Biology. 10: 468-73. PMID 9719867 DOI: 10.1016/S0955-0674(98)80060-4  0.424
1998 Muth TR, Gottardi CJ, Roush DL, Caplan MJ. A basolateral sorting signal is encoded in the α-subunit of Na-K- ATPase American Journal of Physiology - Cell Physiology. 274: C688-C696. PMID 9530100 DOI: 10.1152/Ajpcell.1998.274.3.C688  0.814
1998 Gottardi CJ, Caplan MJ. Signals and Mechanisms of Sorting in Epithelial Polarity Advances in Molecular and Cell Biology. 26: 95-131. DOI: 10.1016/S1569-2558(08)60020-X  0.672
1997 Dunbar LA, Roush DL, Courtois-Coutry N, Muth TR, Gottardi CJ, Rajendran V, Geibel J, Kashgarian M, Caplan MJ. Sorting of ion pumps in polarized epithelial cells Annals of the New York Academy of Sciences. 834: 514-523. PMID 9405853 DOI: 10.1111/J.1749-6632.1997.Tb52309.X  0.78
1997 Muth TR, Dunbar LA, Cortois-Coutry N, Roush DL, Caplan MJ. Sorting and trafficking of ion transport proteins in polarized epithelial cells Current Opinion in Nephrology and Hypertension. 6: 455-459. PMID 9327204 DOI: 10.1097/00041552-199709000-00008  0.812
1997 Courtois-Coutry N, Roush D, Rajendran V, McCarthy JB, Geibel J, Kashgarian M, Caplan MJ. A tyrosine-based signal targets H/K-ATPase to a regulated compartment and is required for the cessation of gastric acid secretion. Cell. 90: 501-10. PMID 9267030 DOI: 10.1016/S0092-8674(00)80510-3  0.393
1997 Caplan MJ. Ion pumps in epithelial cells: Sorting, stabilization, and polarity American Journal of Physiology - Gastrointestinal and Liver Physiology. 272. PMID 9227464 DOI: 10.1152/ajpgi.1997.272.6.G1304  0.343
1997 Caplan MJ. Membrane polarity in epithelial cells: protein sorting and establishment of polarized domains. The American Journal of Physiology. 272: F425-9. PMID 9140041 DOI: 10.1152/Ajprenal.1997.272.4.F425  0.476
1997 Perego C, Bulbarelli A, Longhi R, Caimi M, Villa A, Caplan MJ, Pietrini G. Sorting of two polytopic proteins, the gamma-aminobutyric acid and betaine transporters, in polarized epithelial cells. The Journal of Biological Chemistry. 272: 6584-92. PMID 9045687 DOI: 10.1074/Jbc.272.10.6584  0.428
1996 Caplan MJ. Sorting of GABA transporter proteins in polarized cells Neurochemistry International. 29: 357-360. PMID 8939443 DOI: 10.1016/0197-0186(95)00159-X  0.354
1996 Grishin AV, Bevensee MO, Modyanov NN, Rajendran V, Boron WF, Caplan MJ. Functional expression of the cDNA encoded by the human ATP1AL1 gene American Journal of Physiology. 271: F539-F551. PMID 8853415 DOI: 10.1152/Ajprenal.1996.271.3.F539  0.449
1996 Brill SR, Ross KE, Davidow CJ, Ye M, Grantham JJ, Caplan MJ. Immunolocalization of ion transport proteins in human autosomal dominant polycystic kidney epithelial cells. Proceedings of the National Academy of Sciences of the United States of America. 93: 10206-11. PMID 8816777 DOI: 10.1073/pnas.93.19.10206  0.394
1996 Andreose JS, Fumagalli G, Sigworth FJ, Caplan MJ. Real-time detection of the surface delivery of newly synthesized membrane proteins. Proceedings of the National Academy of Sciences of the United States of America. 93: 7661-6. PMID 8755532 DOI: 10.1073/Pnas.93.15.7661  0.405
1996 Gu HH, Ahn J, Caplan MJ, Blakely RD, Levey AI, Rudnick G. Cell-specific sorting of biogenic amine transporters expressed in epithelial cells. The Journal of Biological Chemistry. 271: 18100-6. PMID 8663573 DOI: 10.1074/Jbc.271.30.18100  0.423
1996 Ahn J, Mundigl O, Muth TR, Rudnick G, Caplan MJ. Polarized expression of GABA transporters in Madin-Darby canine kidney cells and cultured hippocampal neurons. The Journal of Biological Chemistry. 271: 6917-24. PMID 8636119 DOI: 10.1074/Jbc.271.12.6917  0.746
1995 Gottardi CJ, Dunbar LA, Caplan MJ. Biotinylation and assessment of membrane polarity: caveats and methodological concerns. The American Journal of Physiology. 268: F285-95. PMID 7864168 DOI: 10.1152/Ajprenal.1995.268.2.F285  0.798
1995 Fisone G, Snyder GL, Fryckstedt J, Caplan MJ, Aperia A, Greengard P. Na+,K(+)-ATPase in the choroid plexus. Regulation by serotonin/protein kinase C pathway. The Journal of Biological Chemistry. 270: 2427-30. PMID 7852300 DOI: 10.1074/Jbc.270.6.2427  0.396
1995 Shiel MJ, Caplan MJ. Developmental regulation of membrane protein sorting in Drosophila embryos. The American Journal of Physiology. 269: C207-16. PMID 7631747 DOI: 10.1152/Ajpcell.1995.269.1.C207  0.446
1995 Shiel MJ, Caplan MJ. The generation of epithelial polarity in mammalian and Drosophila embryos Seminars in Developmental Biology. 6: 39-46. DOI: 10.1016/S1044-5781(06)80083-6  0.364
1994 Roush DL, Gottardi CJ, Caplan MJ. Sorting of the gastric H,K-ATPase in endocrine and epithelial cells Annals of the New York Academy of Sciences. 733: 212-222. PMID 7978870 DOI: 10.1111/J.1749-6632.1994.Tb17271.X  0.642
1994 Gottardi CJ, Pietrini G, Shiel MJ, Caplan MJ. Synthesis and sorting of ion pumps in polarized cells Current Topics in Membranes. 41: 143-168. DOI: 10.1016/S0070-2161(08)60458-X  0.672
1993 Gottardi CJ, Caplan MJ. Molecular requirements for the cell-surface expression of multisubunit ion-transporting ATPases. Identification of protein domains that participate in Na,K-ATPase and H,K-ATPase subunit assembly. The Journal of Biological Chemistry. 268: 14342-7. PMID 8390991  0.619
1993 Blostein R, Zhang R, Gottardi CJ, Caplan MJ. Functional properties of an H,K-ATPase/Na,K-ATPase chimera. The Journal of Biological Chemistry. 268: 10654-8. PMID 8387526  0.63
1993 Gottardi CJ, Caplan MJ. Delivery of Na+,K(+)-ATPase in polarized epithelial cells. Science (New York, N.Y.). 260: 552-4; author reply . PMID 8386395  0.643
1993 Zurzolo C, Rodriguez-Boulan E, Gottardi CJ, Caplan MJ, Siemers KA, Wilson R, Mays RW, Ryan TA, Wollner DA, Nelson WJ. Delivery of Na+,K+-ATPase in polarized epithelial cells Science. 260: 550-556. PMID 8386394 DOI: 10.1126/Science.8386394  0.675
1993 Gottardi CJ, Caplan MJ. An ion-transporting ATPase encodes multiple apical localization signals. The Journal of Cell Biology. 121: 283-93. PMID 8385670 DOI: 10.1083/Jcb.121.2.283  0.711
1993 Gottardi CJ, Pietrini G, Roush DL, Caplan MJ. Sorting of ion transport proteins in polarized cells Journal of Cell Science. Supplement. 17: 13-20. PMID 8144688 DOI: 10.1242/Jcs.1993.Supplement_17.3  0.708
1992 Pietrini G, Matteoli M, Banker G, Caplan MJ. Isoforms of the Na,K-ATPase are present in both axons and dendrites of hippocampal neurons in culture. Proceedings of the National Academy of Sciences of the United States of America. 89: 8414-18. PMID 1326755 DOI: 10.1073/Pnas.89.18.8414  0.376
1992 Gottardi CJ, Caplan MJ. Cell surface biotinylation in the determination of epithelial membrane polarity Journal of Tissue Culture Methods. 14: 173-180. DOI: 10.1007/Bf01409008  0.659
1991 Boll W, Partin JS, Katz AI, Caplan MJ, Jamieson JD. Distinct pathways for basolateral targeting of membrane and secretory proteins in polarized epithelial cells. Proceedings of the National Academy of Sciences of the United States of America. 88: 8592-6. PMID 1656451 DOI: 10.1073/Pnas.88.19.8592  0.762
1991 Caplan MJ. Biogenesis and sorting of plasma membrane proteins Current Topics in Membranes. 39: 37-86. DOI: 10.1016/S0070-2161(08)60800-X  0.427
1990 Caplan MJ, Forbush B, Palade GE, Jamieson JD. Biosynthesis of the Na,K-ATPase in Madin-Darby canine kidney cells. Activation and cell surface delivery. The Journal of Biological Chemistry. 265: 3528-34. PMID 2154482  0.812
1988 Caplan MJ, Anderson HC, Palade GE, Jamieson JD. Sorting of newly synthesized Na,K-ATPase in polarized epithelial cells. Progress in Clinical and Biological Research. 268: 51-8. PMID 2851829  0.811
1988 Smith ZD, Caplan MJ, Jamieson JD. Immunocytochemical localization of plasmalemmal proteins in semi-thin sections of epithelial monolayers. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 36: 311-6. PMID 2449492 DOI: 10.1177/36.3.2449492  0.753
1987 Sztul ES, Biemesderfer D, Caplan MJ, Kashgarian M, Boyer JL. Localization of Na+,K+-ATPase alpha-subunit to the sinusoidal and lateral but not canalicular membranes of rat hepatocytes. The Journal of Cell Biology. 104: 1239-48. PMID 3032985 DOI: 10.1083/Jcb.104.5.1239  0.655
1987 Caplan MJ, Stow JL, Newman AP, Madri J, Anderson HC, Farquhar MG, Palade GE, Jamieson JD. Dependence on pH of polarized sorting of secreted proteins. Nature. 329: 632-5. PMID 2821405 DOI: 10.1038/329632a0  0.824
1987 Smith ZD, Caplan MJ, Forbush B, Jamieson JD. Monoclonal antibody localization of Na+-K+-ATPase in the exocrine pancreas and parotid of the dog. The American Journal of Physiology. 253: G99-109. PMID 2441610 DOI: 10.1152/Ajpgi.1987.253.2.G99  0.734
1986 Caplan MJ, Anderson HC, Palade GE, Jamieson JD. Intracellular sorting and polarized cell surface delivery of (Na+,K+)ATPase, an endogenous component of MDCK cell basolateral plasma membranes. Cell. 46: 623-31. PMID 3015421 DOI: 10.1016/0092-8674(86)90888-3  0.828
1986 Caplan MJ, Palade GE, Jamieson JD. Newly synthesized Na,K-ATPase alpha-subunit has no cytosolic intermediate in MDCK cells. The Journal of Biological Chemistry. 261: 2860-5. PMID 3005269  0.785
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