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John M. Essigmann - Publications

Chemistry and Biological Engineering Massachusetts Institute of Technology, Cambridge, MA, United States 
Mutagenesis, Carcinogenesis, Anticancer Drug Design

165 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Kay JE, Corrigan JJ, Armijo AL, Nazari IS, Kohale IN, Torous DK, Avlasevich SL, Croy RG, Wadduwage DN, Carrasco SE, Dertinger SD, White FM, Essigmann JM, Samson LD, Engelward BP. Excision of mutagenic replication-blocking lesions suppresses cancer but promotes cytotoxicity and lethality in nitrosamine-exposed mice. Cell Reports. 34: 108864. PMID 33730582 DOI: 10.1016/j.celrep.2021.108864  0.8
2021 Tajai P, Suriyo T, Rangkadilok N, Fedeles B, Essigmann JM, Satayavivad J. Andrographolide, an Antioxidant, Counteracts Paraquat- Induced Mutagenesis in Mammalian Cells. Asian Pacific Journal of Cancer Prevention : Apjcp. 22: 3-8. PMID 33576206 DOI: 10.31557/APJCP.2021.22.S1.3  0.52
2019 Thongararm P, Fedeles BI, Khumsubdee S, Armijo AL, Kim L, Thiantanawat A, Promvijit J, Navasumrit P, Ruchirawat M, Croy RG, Essigmann JM. Modulation of N-Methyl-N-nitrosourea Mutagenesis in Mouse Embryo Fibroblasts Derived from the Delta Mouse by an Inhibitor of the O-Methylguanine Methyltransferase, MGMT. Chemical Research in Toxicology. PMID 31841318 DOI: 10.1021/Acs.Chemrestox.9B00444  0.8
2019 He M, Croy RG, Essigmann JM, Swager TM. Chemiresistive Carbon Nanotube Sensors for -Nitrosodialkylamines. Acs Sensors. PMID 31573183 DOI: 10.1021/Acssensors.9B01532  0.8
2019 Ge Z, Feng Y, Sheh A, Muthupalani S, Gong G, Chawanthayatham S, Essigmann JM, Fox JG. Mutagenicity of Helicobacter hepaticus infection in the lower bowel mucosa of 129/SvEv Rag2 Il10 gpt delta mice is influenced by sex. International Journal of Cancer. PMID 30977112 DOI: 10.1002/Ijc.32332  0.64
2018 Fedeles BI, Essigmann JM. Impact of DNA lesion repair, replication and formation on the mutational spectra of environmental carcinogens: Aflatoxin B as a case study. Dna Repair. PMID 30309820 DOI: 10.1016/J.Dnarep.2018.08.008  0.52
2017 Sriwattanapong K, Slocum SL, Chawanthayatham S, Fedeles BI, Egner PA, Groopman JD, Satayavivad J, Croy RG, Essigmann JM. Pregnancy alters aflatoxin B1 metabolism and increases DNA damage in mouse liver. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 28973694 DOI: 10.1093/Toxsci/Kfx171  0.8
2017 Fedeles BI, Chawanthayatham S, Croy RG, Wogan GN, Essigmann JM. Early detection of the aflatoxin B1 mutational fingerprint: A diagnostic tool for liver cancer. Molecular & Cellular Oncology. 4: e1329693. PMID 28868344 DOI: 10.1080/23723556.2017.1329693  0.96
2017 Vartanian V, Minko IG, Chawanthayatham S, Egner PA, Lin YC, Earley LF, Makar R, Eng JR, Camp MT, Li L, Stone MP, Lasarev MR, Groopman JD, Croy RG, Essigmann JM, et al. NEIL1 protects against aflatoxin-induced hepatocellular carcinoma in mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 28373545 DOI: 10.1073/Pnas.1620932114  0.8
2017 Chawanthayatham S, Valentine CC, Fedeles BI, Fox EJ, Loeb LA, Levine SS, Slocum SL, Wogan GN, Croy RG, Essigmann JM. Mutational spectra of aflatoxin B1 in vivo establish biomarkers of exposure for human hepatocellular carcinoma. Proceedings of the National Academy of Sciences of the United States of America. PMID 28351974 DOI: 10.1073/Pnas.1700759114  0.96
2017 Chen F, Bian K, Tang Q, Fedeles BI, Singh V, Humulock ZT, Essigmann JM, Li D. Oncometabolites D- and L-2-hydroxyglutarate Inhibit the AlkB Family DNA Repair Enzymes under Physiological Conditions. Chemical Research in Toxicology. PMID 28269980 DOI: 10.1021/Acs.Chemrestox.7B00009  0.52
2015 Fedeles BI, Freudenthal BD, Yau E, Singh V, Chang SC, Li D, Delaney JC, Wilson SH, Essigmann JM. Intrinsic mutagenic properties of 5-chlorocytosine: A mechanistic connection between chronic inflammation and cancer. Proceedings of the National Academy of Sciences of the United States of America. 112: E4571-80. PMID 26243878 DOI: 10.1073/Pnas.1507709112  1
2015 Fedeles BI, Singh V, Delaney JC, Li D, Essigmann JM. The AlkB Family of Fe(II)/α-Ketoglutarate Dependent Dioxygenases: Repairing Nucleic Acid Alkylation Damage and Beyond. The Journal of Biological Chemistry. PMID 26152727 DOI: 10.1074/Jbc.R115.656462  1
2015 Chang SC, Fedeles BI, Wu J, Delaney JC, Li D, Zhao L, Christov PP, Yau E, Singh V, Jost M, Drennan CL, Marnett LJ, Rizzo CJ, Levine SS, Guengerich FP, ... Essigmann JM, et al. Next-generation sequencing reveals the biological significance of the N2,3-ethenoguanine lesion in vivo. Nucleic Acids Research. 43: 5489-500. PMID 25837992 DOI: 10.1093/Nar/Gkv243  1
2015 Peng CS, Fedeles BI, Singh V, Li D, Amariuta T, Essigmann JM, Tokmakoff A. Two-dimensional IR spectroscopy of the anti-HIV agent KP1212 reveals protonated and neutral tautomers that influence pH-dependent mutagenicity. Proceedings of the National Academy of Sciences of the United States of America. 112: 3229-34. PMID 25733867 DOI: 10.1073/Pnas.1415974112  1
2015 Singh V, Fedeles BI, Essigmann JM. Role of tautomerism in RNA biochemistry. Rna (New York, N.Y.). 21: 1-13. PMID 25516996 DOI: 10.1261/Rna.048371.114  1
2015 Techapiesancharoenkij N, Fiala JL, Navasumrit P, Croy RG, Wogan GN, Groopman JD, Ruchirawat M, Essigmann JM. Sulforaphane, a cancer chemopreventive agent, induces pathways associated with membrane biosynthesis in response to tissue damage by aflatoxin B1. Toxicology and Applied Pharmacology. 282: 52-60. PMID 25450479 DOI: 10.1016/J.Taap.2014.11.004  1
2015 Chawanthayatham S, Thiantanawat A, Egner PA, Groopman JD, Wogan GN, Croy RG, Essigmann JM. Prenatal exposure of mice to the human liver carcinogen aflatoxin B1 reveals a critical window of susceptibility to genetic change. International Journal of Cancer. Journal International Du Cancer. 136: 1254-62. PMID 25070670 DOI: 10.1002/Ijc.29102  1
2014 Singh V, Fedeles BI, Li D, Delaney JC, Kozekov ID, Kozekova A, Marnett LJ, Rizzo CJ, Essigmann JM. Mechanism of repair of acrolein- and malondialdehyde-derived exocyclic guanine adducts by the α-ketoglutarate/Fe(II) dioxygenase AlkB. Chemical Research in Toxicology. 27: 1619-31. PMID 25157679 DOI: 10.1021/Tx5002817  1
2014 Li D, Fedeles BI, Singh V, Peng CS, Silvestre KJ, Simi AK, Simpson JH, Tokmakoff A, Essigmann JM. Tautomerism provides a molecular explanation for the mutagenic properties of the anti-HIV nucleoside 5-aza-5,6-dihydro-2'-deoxycytidine. Proceedings of the National Academy of Sciences of the United States of America. 111: E3252-9. PMID 25071207 DOI: 10.1073/Pnas.1405635111  1
2014 Shrivastav N, Fedeles BI, Li D, Delaney JC, Frick LE, Foti JJ, Walker GC, Essigmann JM. A chemical genetics analysis of the roles of bypass polymerase DinB and DNA repair protein AlkB in processing N2-alkylguanine lesions in vivo. Plos One. 9: e94716. PMID 24733044 DOI: 10.1371/Journal.Pone.0094716  1
2014 Singh V, Peng CS, Li D, Mitra K, Silvestre KJ, Tokmakoff A, Essigmann JM. Direct observation of multiple tautomers of oxythiamine and their recognition by the thiamine pyrophosphate riboswitch. Acs Chemical Biology. 9: 227-36. PMID 24252063 DOI: 10.1021/Cb400581F  1
2013 Li D, Fedeles BI, Shrivastav N, Delaney JC, Yang X, Wong C, Drennan CL, Essigmann JM. Removal of N-alkyl modifications from N(2)-alkylguanine and N(4)-alkylcytosine in DNA by the adaptive response protein AlkB. Chemical Research in Toxicology. 26: 1182-7. PMID 23773213 DOI: 10.1021/Tx400096M  1
2012 Hanson RN, Hua E, Labaree D, Hochberg RB, Proffitt K, Essigmann JM, Croy RG. Convergent synthesis of a steroidal antiestrogen-mitomycin C hybrid using "click" chemistry. Organic & Biomolecular Chemistry. 10: 8501-8. PMID 23007562 DOI: 10.1039/C2Ob25902H  1
2012 Wattanawaraporn R, Kim MY, Adams J, Trudel LJ, Woo LL, Croy RG, Essigmann JM, Wogan GN. AFB(1) -induced mutagenesis of the gpt gene in AS52 cells. Environmental and Molecular Mutagenesis. 53: 567-73. PMID 22733615 DOI: 10.1002/Em.21711  1
2012 Wattanawaraporn R, Woo LL, Belanger C, Chang SC, Adams JE, Trudel LJ, Bouhenguel JT, Egner PA, Groopman JD, Croy RG, Essigmann JM, Wogan GN. A single neonatal exposure to aflatoxin b1 induces prolonged genetic damage in two loci of mouse liver. Toxicological Sciences : An Official Journal of the Society of Toxicology. 128: 326-33. PMID 22539618 DOI: 10.1093/Toxsci/Kfs151  1
2012 Li D, Delaney JC, Page CM, Yang X, Chen AS, Wong C, Drennan CL, Essigmann JM. Exocyclic carbons adjacent to the N6 of adenine are targets for oxidation by the Escherichia coli adaptive response protein AlkB. Journal of the American Chemical Society. 134: 8896-901. PMID 22512456 DOI: 10.1021/Ja3010094  1
2011 Fedeles BI, Zhu AY, Young KS, Hillier SM, Proffitt KD, Essigmann JM, Croy RG. Chemical genetics analysis of an aniline mustard anticancer agent reveals complex I of the electron transport chain as a target. The Journal of Biological Chemistry. 286: 33910-20. PMID 21832047 DOI: 10.1074/Jbc.M111.278390  1
2011 Rechkoblit O, Delaney JC, Essigmann JM, Patel DJ. Implications for damage recognition during Dpo4-mediated mutagenic bypass of m1G and m3C lesions. Structure (London, England : 1993). 19: 821-32. PMID 21645853 DOI: 10.1016/J.Str.2011.03.020  1
2011 Woo LL, Egner PA, Belanger CL, Wattanawaraporn R, Trudel LJ, Croy RG, Groopman JD, Essigmann JM, Wogan GN, Bouhenguel JT. Aflatoxin B1-DNA adduct formation and mutagenicity in livers of neonatal male and female B6C3F1 mice. Toxicological Sciences : An Official Journal of the Society of Toxicology. 122: 38-44. PMID 21507988 DOI: 10.1093/Toxsci/Kfr087  1
2011 Fiala JL, Egner PA, Wiriyachan N, Ruchirawat M, Kensler KH, Wogan GN, Groopman JD, Croy RG, Essigmann JM. Sulforaphane-mediated reduction of aflatoxin B₁-N⁷-guanine in rat liver DNA: impacts of strain and sex. Toxicological Sciences : An Official Journal of the Society of Toxicology. 121: 57-62. PMID 21278056 DOI: 10.1093/Toxsci/Kfr026  1
2011 Mullins JI, Heath L, Hughes JP, Kicha J, Styrchak S, Wong KG, Rao U, Hansen A, Harris KS, Laurent JP, Li D, Simpson JH, Essigmann JM, Loeb LA, Parkins J. Mutation of HIV-1 genomes in a clinical population treated with the mutagenic nucleoside KP1461. Plos One. 6: e15135. PMID 21264288 DOI: 10.1371/Journal.Pone.0015135  1
2010 Li D, Delaney JC, Page CM, Chen AS, Wong C, Drennan CL, Essigmann JM. Repair of DNA Alkylation Damage by the Escherichia coli Adaptive Response Protein AlkB as Studied by ESI-TOF Mass Spectrometry. Journal of Nucleic Acids. 2010: 369434. PMID 21048928 DOI: 10.4061/2010/369434  1
2010 Shrivastav N, Li D, Essigmann JM. Chemical biology of mutagenesis and DNA repair: cellular responses to DNA alkylation. Carcinogenesis. 31: 59-70. PMID 19875697 DOI: 10.1093/Carcin/Bgp262  1
2010 Fox JG, Feng Y, Theve EJ, Raczynski AR, Fiala JL, Doernte AL, Williams M, McFaline JL, Essigmann JM, Schauer DB, Tannenbaum SR, Dedon PC, Weinman SA, Lemon SM, Fry RC, et al. Gut microbes define liver cancer risk in mice exposed to chemical and viral transgenic hepatocarcinogens. Gut. 59: 88-97. PMID 19850960 DOI: 10.1136/Gut.2009.183749  1
2009 Jarosz DF, Cohen SE, Delaney JC, Essigmann JM, Walker GC. A DinB variant reveals diverse physiological consequences of incomplete TLS extension by a Y-family DNA polymerase. Proceedings of the National Academy of Sciences of the United States of America. 106: 21137-42. PMID 19948952 DOI: 10.1073/Pnas.0907257106  1
2009 Delaney JC, Gao J, Liu H, Shrivastav N, Essigmann JM, Kool ET. Efficient replication bypass of size-expanded DNA base pairs in bacterial cells. Angewandte Chemie (International Ed. in English). 48: 4524-7. PMID 19444841 DOI: 10.1002/Anie.200805683  1
2009 Lee CY, Delaney JC, Kartalou M, Lingaraju GM, Maor-Shoshani A, Essigmann JM, Samson LD. Recognition and processing of a new repertoire of DNA substrates by human 3-methyladenine DNA glycosylase (AAG). Biochemistry. 48: 1850-61. PMID 19219989 DOI: 10.1021/Bi8018898  1
2009 Mundle ST, Delaney JC, Essigmann JM, Strauss PR. Enzymatic mechanism of human apurinic/apyrimidinic endonuclease against a THF AP site model substrate. Biochemistry. 48: 19-26. PMID 19123919 DOI: 10.1021/Bi8016137  1
2009 Kim E, Rye PT, Essigmann JM, Croy RG. A bifunctional platinum(II) antitumor agent that forms DNA adducts with affinity for the estrogen receptor. Journal of Inorganic Biochemistry. 103: 256-61. PMID 19054566 DOI: 10.1016/J.Jinorgbio.2008.10.013  1
2008 Delaney JC, Essigmann JM. Biological properties of single chemical-DNA adducts: a twenty year perspective. Chemical Research in Toxicology. 21: 232-52. PMID 18072751 DOI: 10.1021/Tx700292A  1
2008 Rye PT, Delaney JC, Netirojjanakul C, Sun DX, Liu JZ, Essigmann JM. Mismatch repair proteins collaborate with methyltransferases in the repair of O(6)-methylguanine. Dna Repair. 7: 170-6. PMID 17951114 DOI: 10.1016/J.Dnarep.2007.09.003  1
2007 Delaney S, Delaney JC, Essigmann JM. Chemical-biological fingerprinting: probing the properties of DNA lesions formed by peroxynitrite. Chemical Research in Toxicology. 20: 1718-29. PMID 17941698 DOI: 10.1021/Tx700273U  1
2007 Patro JN, Wiederholt CJ, Jiang YL, Delaney JC, Essigmann JM, Greenberg MM. Studies on the replication of the ring opened formamidopyrimidine, Fapy.dG in Escherichia coli. Biochemistry. 46: 10202-12. PMID 17691820 DOI: 10.1021/Bi700628C  1
2007 Kim MY, Zhou X, Delaney JC, Taghizadeh K, Dedon PC, Essigmann JM, Wogan GN. AlkB influences the chloroacetaldehyde-induced mutation spectra and toxicity in the pSP189 supF shuttle vector. Chemical Research in Toxicology. 20: 1075-83. PMID 17658757 DOI: 10.1021/Tx700167V  1
2007 Neeley WL, Delaney S, Alekseyev YO, Jarosz DF, Delaney JC, Walker GC, Essigmann JM. DNA polymerase V allows bypass of toxic guanine oxidation products in vivo. The Journal of Biological Chemistry. 282: 12741-8. PMID 17322566 DOI: 10.1074/Jbc.M700575200  1
2007 Delaney S, Neeley WL, Delaney JC, Essigmann JM. The substrate specificity of MutY for hyperoxidized guanine lesions in vivo. Biochemistry. 46: 1448-55. PMID 17260974 DOI: 10.1021/Bi061174H  1
2007 Frick LE, Delaney JC, Wong C, Drennan CL, Essigmann JM. Alleviation of 1,N6-ethanoadenine genotoxicity by the Escherichia coli adaptive response protein AlkB. Proceedings of the National Academy of Sciences of the United States of America. 104: 755-60. PMID 17213319 DOI: 10.1073/Pnas.0607377104  1
2006 Delaney JC, Essigmann JM. Assays for determining lesion bypass efficiency and mutagenicity of site-specific DNA lesions in vivo. Methods in Enzymology. 408: 1-15. PMID 16793359 DOI: 10.1016/S0076-6879(06)08001-3  1
2006 Hillier SM, Marquis JC, Zayas B, Wishnok JS, Liberman RG, Skipper PL, Tannenbaum SR, Essigmann JM, Croy RG. DNA adducts formed by a novel antitumor agent 11beta-dichloro in vitro and in vivo. Molecular Cancer Therapeutics. 5: 977-84. PMID 16648569 DOI: 10.1158/1535-7163.Mct-05-0464  1
2006 Neeley WL, Essigmann JM. Mechanisms of formation, genotoxicity, and mutation of guanine oxidation products. Chemical Research in Toxicology. 19: 491-505. PMID 16608160 DOI: 10.1021/Tx0600043  1
2006 Jarosz DF, Godoy VG, Delaney JC, Essigmann JM, Walker GC. A single amino acid governs enhanced activity of DinB DNA polymerases on damaged templates. Nature. 439: 225-8. PMID 16407906 DOI: 10.1038/Nature04318  1
2005 Kim TW, Delaney JC, Essigmann JM, Kool ET. Probing the active site tightness of DNA polymerase in subangstrom increments. Proceedings of the National Academy of Sciences of the United States of America. 102: 15803-8. PMID 16249340 DOI: 10.1073/Pnas.0505113102  1
2005 Delaney JC, Smeester L, Wong C, Frick LE, Taghizadeh K, Wishnok JS, Drennan CL, Samson LD, Essigmann JM. AlkB reverses etheno DNA lesions caused by lipid oxidation in vitro and in vivo. Nature Structural & Molecular Biology. 12: 855-60. PMID 16200073 DOI: 10.1038/Nsmb996  1
2005 Robbins-Manke JL, Zdraveski ZZ, Marinus M, Essigmann JM. Analysis of global gene expression and double-strand-break formation in DNA adenine methyltransferase- and mismatch repair-deficient Escherichia coli. Journal of Bacteriology. 187: 7027-37. PMID 16199573 DOI: 10.1128/Jb.187.20.7027-7037.2005  1
2005 Marquis JC, Hillier SM, Dinaut AN, Rodrigues D, Mitra K, Essigmann JM, Croy RG. Disruption of gene expression and induction of apoptosis in prostate cancer cells by a DNA-damaging agent tethered to an androgen receptor ligand. Chemistry & Biology. 12: 779-87. PMID 16039525 DOI: 10.1016/J.Chembiol.2005.05.009  1
2005 Henderson PT, Neeley WL, Delaney JC, Gu F, Niles JC, Hah SS, Tannenbaum SR, Essigmann JM. Urea lesion formation in DNA as a consequence of 7,8-dihydro-8-oxoguanine oxidation and hydrolysis provides a potent source of point mutations. Chemical Research in Toxicology. 18: 12-8. PMID 15651843 DOI: 10.1021/Tx049757K  1
2004 Kosa JL, Zdraveski ZZ, Currier S, Marinus MG, Essigmann JM. RecN and RecG are required for Escherichia coli survival of Bleomycin-induced damage. Mutation Research. 554: 149-57. PMID 15450413 DOI: 10.1016/J.Mrfmmm.2004.04.011  1
2004 Delaney JC, Essigmann JM. Mutagenesis, genotoxicity, and repair of 1-methyladenine, 3-alkylcytosines, 1-methylguanine, and 3-methylthymine in alkB Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 101: 14051-6. PMID 15381779 DOI: 10.1073/Pnas.0403489101  1
2004 Neeley WL, Delaney JC, Henderson PT, Essigmann JM. In vivo bypass efficiencies and mutational signatures of the guanine oxidation products 2-aminoimidazolone and 5-guanidino-4-nitroimidazole. The Journal of Biological Chemistry. 279: 43568-73. PMID 15299010 DOI: 10.1074/Jbc.M407117200  1
2004 Sharma U, Marquis JC, Nicole Dinaut A, Hillier SM, Fedeles B, Rye PT, Essigmann JM, Croy RG. Design, synthesis, and evaluation of estradiol-linked genotoxicants as anti-cancer agents. Bioorganic & Medicinal Chemistry Letters. 14: 3829-33. PMID 15203171 DOI: 10.1016/J.Bmcl.2004.04.064  1
2004 Nowosielska A, Calmann MA, Zdraveski Z, Essigmann JM, Marinus MG. Spontaneous and cisplatin-induced recombination in Escherichia coli. Dna Repair. 3: 719-28. PMID 15177181 DOI: 10.1016/J.Dnarep.2004.02.009  1
2004 Alekseyev YO, Hamm ML, Essigmann JM. Aflatoxin B1 formamidopyrimidine adducts are preferentially repaired by the nucleotide excision repair pathway in vivo. Carcinogenesis. 25: 1045-51. PMID 14742311 DOI: 10.1093/Carcin/Bgh098  1
2004 Neeley WL, Henderson PT, Essigmann JM. Efficient synthesis of DNA containing the guanine oxidation-nitration product 5-guanidino-4-nitroimidazole: generation by a postsynthetic substitution reaction. Organic Letters. 6: 245-8. PMID 14723539 DOI: 10.1021/Ol036188J  1
2003 Henderson PT, Delaney JC, Muller JG, Neeley WL, Tannenbaum SR, Burrows CJ, Essigmann JM. The hydantoin lesions formed from oxidation of 7,8-dihydro-8-oxoguanine are potent sources of replication errors in vivo. Biochemistry. 42: 9257-62. PMID 12899611 DOI: 10.1021/Bi0347252  1
2003 Delaney JC, Henderson PT, Helquist SA, Morales JC, Essigmann JM, Kool ET. High-fidelity in vivo replication of DNA base shape mimics without Watson-Crick hydrogen bonds. Proceedings of the National Academy of Sciences of the United States of America. 100: 4469-73. PMID 12676985 DOI: 10.1073/Pnas.0837277100  1
2002 Smela ME, Hamm ML, Henderson PT, Harris CM, Harris TM, Essigmann JM. The aflatoxin B(1) formamidopyrimidine adduct plays a major role in causing the types of mutations observed in human hepatocellular carcinoma. Proceedings of the National Academy of Sciences of the United States of America. 99: 6655-60. PMID 12011430 DOI: 10.1073/Pnas.102167699  1
2002 Mitra K, Marquis JC, Hillier SM, Rye PT, Zayas B, Lee AS, Essigmann JM, Croy RG. A rationally designed genotoxin that selectively destroys estrogen receptor-positive breast cancer cells. Journal of the American Chemical Society. 124: 1862-3. PMID 11866593 DOI: 10.1021/Ja017344P  1
2002 Henderson PT, Delaney JC, Gu F, Tannenbaum SR, Essigmann JM. Oxidation of 7,8-dihydro-8-oxoguanine affords lesions that are potent sources of replication errors in vivo. Biochemistry. 41: 914-21. PMID 11790114 DOI: 10.1021/Bi0156355  1
2002 Zdraveski ZZ, Mello JA, Farinelli CK, Essigmann JM, Marinus MG. MutS preferentially recognizes cisplatin- over oxaliplatin-modified DNA. The Journal of Biological Chemistry. 277: 1255-60. PMID 11705991 DOI: 10.1074/Jbc.M105382200  1
2001 Essigmann JM, Rink SM, Park HJ, Croy RG. Design of DNA damaging agents that hijack transcription factors and block DNA repair. Advances in Experimental Medicine and Biology. 500: 301-13. PMID 11764957 DOI: 10.1007/978-1-4615-0667-6_47  1
2001 Delaney JC, Essigmann JM. Effect of sequence context on O(6)-methylguanine repair and replication in vivo. Biochemistry. 40: 14968-75. PMID 11732917 DOI: 10.1021/Bi015578F  1
2001 Kartalou M, Essigmann JM. Mechanisms of resistance to cisplatin. Mutation Research. 478: 23-43. PMID 11406167 DOI: 10.1016/S0027-5107(01)00141-5  1
2001 Kartalou M, Essigmann JM. Recognition of cisplatin adducts by cellular proteins. Mutation Research. 478: 1-21. PMID 11406166 DOI: 10.1016/S0027-5107(01)00142-7  1
2001 Eide L, Luna L, Gustad EC, Henderson PT, Essigmann JM, Demple B, Seeberg E. Human endonuclease III acts preferentially on DNA damage opposite guanine residues in DNA. Biochemistry. 40: 6653-9. PMID 11380260 DOI: 10.1021/Bi0028901  1
2001 Smela ME, Currier SS, Bailey EA, Essigmann JM. The chemistry and biology of aflatoxin B(1): from mutational spectrometry to carcinogenesis. Carcinogenesis. 22: 535-45. PMID 11285186 DOI: 10.1093/Carcin/22.4.535  1
2000 Kartalou M, Samson LD, Essigmann JM. Cisplatin adducts inhibit 1,N(6)-ethenoadenine repair by interacting with the human 3-methyladenine DNA glycosylase. Biochemistry. 39: 8032-8. PMID 10891085 DOI: 10.1021/Bi000417H  1
2000 Kuraoka I, Kobertz WR, Ariza RR, Biggerstaff M, Essigmann JM, Wood RD. Repair of an interstrand DNA cross-link initiated by ERCC1-XPF repair/recombination nuclease. The Journal of Biological Chemistry. 275: 26632-6. PMID 10882712 DOI: 10.1074/Jbc.C000337200  1
2000 Zdraveski ZZ, Mello JA, Marinus MG, Essigmann JM. Multiple pathways of recombination define cellular responses to cisplatin. Chemistry & Biology. 7: 39-50. PMID 10662689 DOI: 10.1016/S1074-5521(00)00064-8  1
1999 Trimmer EE, Essigmann JM. Cisplatin. Essays in Biochemistry. 34: 191-211. PMID 10730196  1
1999 Delaney JC, Essigmann JM. Context-dependent mutagenesis by DNA lesions. Chemistry & Biology. 6: 743-53. PMID 10508678 DOI: 10.1016/S1074-5521(00)80021-6  1
1999 Avery AM, Kaur B, Taylor JS, Mello JA, Essigmann JM, Doetsch PW. Substrate specificity of ultraviolet DNA endonuclease (UVDE/Uve1p) from Schizosaccharomyces pombe. Nucleic Acids Research. 27: 2256-64. PMID 10325412 DOI: 10.1093/Nar/27.11.2256  1
1999 Cullinane C, Mazur SJ, Essigmann JM, Phillips DR, Bohr VA. Inhibition of RNA polymerase II transcription in human cell extracts by cisplatin DNA damage. Biochemistry. 38: 6204-12. PMID 10320349 DOI: 10.1021/Bi982685+  1
1999 Pourquier P, Ueng LM, Fertala J, Wang D, Park HJ, Essigmann JM, Bjornsti MA, Pommier Y. Induction of reversible complexes between eukaryotic DNA topoisomerase I and DNA-containing oxidative base damages. 7, 8-dihydro-8-oxoguanine and 5-hydroxycytosine. The Journal of Biological Chemistry. 274: 8516-23. PMID 10085084 DOI: 10.1074/jbc.274.13.8516  1
1999 Loeb LA, Essigmann JM, Kazazi F, Zhang J, Rose KD, Mullins JI. Lethal mutagenesis of HIV with mutagenic nucleoside analogs. Proceedings of the National Academy of Sciences of the United States of America. 96: 1492-7. PMID 9990051 DOI: 10.1073/Pnas.96.4.1492  1
1998 Marzilli LA, Wang D, Kobertz WR, Essigmann JM, Vouros P. Mass spectral identification and positional mapping of aflatoxin B1-guanine adducts in oligonucleotides. Journal of the American Society For Mass Spectrometry. 9: 676-82. PMID 9879377 DOI: 10.1016/S1044-0305(98)00039-7  1
1998 Zhai X, Beckmann H, Jantzen HM, Essigmann JM. Cisplatin-DNA adducts inhibit ribosomal RNA synthesis by hijacking the transcription factor human upstream binding factor. Biochemistry. 37: 16307-15. PMID 9819223 DOI: 10.1021/Bi981708H  1
1998 Wang D, Kreutzer DA, Essigmann JM. Mutagenicity and repair of oxidative DNA damage: insights from studies using defined lesions. Mutation Research. 400: 99-115. PMID 9685598 DOI: 10.1016/S0027-5107(98)00066-9  1
1998 Kreutzer DA, Essigmann JM. Oxidized, deaminated cytosines are a source of C --> T transitions in vivo. Proceedings of the National Academy of Sciences of the United States of America. 95: 3578-82. PMID 9520408 DOI: 10.1073/Pnas.95.7.3578  1
1998 Trimmer EE, Zamble DB, Lippard SJ, Essigmann JM. Human testis-determining factor SRY binds to the major DNA adduct of cisplatin and a putative target sequence with comparable affinities. Biochemistry. 37: 352-62. PMID 9425057 DOI: 10.1021/Bi971675Q  1
1997 Kobertz WR, Essigmann JM. An Efficient Synthesis of a Furan-Side Furocoumarin Thymidine Monoadduct. The Journal of Organic Chemistry. 62: 2630-2632. PMID 11671608 DOI: 10.1021/Jo9619084  1
1997 Verghis SB, Essigmann JM, Kadlubar FF, Morningstar ML, Lasko DD. Specificity of mutagenesis by 4-aminobiphenyl: mutations at G residues in bacteriophage M13 DNA and G-->C transversions at a unique dG(8-ABP) lesion in single-stranded DNA. Carcinogenesis. 18: 2403-14. PMID 9450488 DOI: 10.1093/Carcin/18.12.2403  1
1997 Morningstar ML, Kreutzer DA, Essigmann JM. Synthesis of oligonucleotides containing two putatively mutagenic DNA lesions: 5-hydroxy-2'-deoxyuridine and 5-hydroxy-2'-deoxycytidine. Chemical Research in Toxicology. 10: 1345-50. PMID 9437524 DOI: 10.1021/Tx970052A  1
1997 Kobertz WR, Wang D, Wogan GN, Essigmann JM. An intercalation inhibitor altering the target selectivity of DNA damaging agents: synthesis of site-specific aflatoxin B1 adducts in a p53 mutational hotspot. Proceedings of the National Academy of Sciences of the United States of America. 94: 9579-84. PMID 9275165 DOI: 10.1073/Pnas.94.18.9579  1
1997 Wang D, Essigmann JM. Kinetics of oxidized cytosine repair by endonuclease III of Escherichia coli. Biochemistry. 36: 8628-33. PMID 9214309 DOI: 10.1021/Bi970341Y  1
1996 Rink SM, Yarema KJ, Solomon MS, Paige LA, Tadayoni-Rebek BM, Essigmann JM, Croy RG. Synthesis and biological activity of DNA damaging agents that form decoy binding sites for the estrogen receptor. Proceedings of the National Academy of Sciences of the United States of America. 93: 15063-8. PMID 8986764 DOI: 10.1073/Pnas.93.26.15063  1
1996 Altshuler KB, Hodes CS, Essigmann JM. Intrachromosomal probes for mutagenesis by alkylated DNA bases replicated in mammalian cells: a comparison of the mutagenicities of O4-methylthymine and O6-methylguanine in cells with different DNA repair backgrounds. Chemical Research in Toxicology. 9: 980-7. PMID 8870985 DOI: 10.1021/Tx960062W  1
1996 Mello JA, Acharya S, Fishel R, Essigmann JM. The mismatch-repair protein hMSH2 binds selectively to DNA adducts of the anticancer drug cisplatin. Chemistry & Biology. 3: 579-89. PMID 8807890 DOI: 10.1016/S1074-5521(96)90149-0  1
1996 Bailey EA, Iyer RS, Harris TM, Essigmann JM. A viral genome containing an unstable aflatoxin B1-N7-guanine DNA adduct situated at a unique site. Nucleic Acids Research. 24: 2821-8. PMID 8759017 DOI: 10.1093/Nar/24.14.2821  1
1996 Solomon MS, Morgenthaler PM, Turesky RJ, Essigmann JM. Mutational and DNA binding specificity of the carcinogen 2-amino-3, 8-dimethylimidazo[4,5-f]quinoxaline. The Journal of Biological Chemistry. 271: 18368-74. PMID 8702479 DOI: 10.1074/Jbc.271.31.18368  1
1996 Bailey EA, Iyer RS, Stone MP, Harris TM, Essigmann JM. Mutational properties of the primary aflatoxin B1-DNA adduct. Proceedings of the National Academy of Sciences of the United States of America. 93: 1535-9. PMID 8643667 DOI: 10.1073/Pnas.93.4.1535  1
1996 Moggs JG, Yarema KJ, Essigmann JM, Wood RD. Analysis of incision sites produced by human cell extracts and purified proteins during nucleotide excision repair of a 1,3-intrastrand d(GpTpG)-cisplatin adduct. The Journal of Biological Chemistry. 271: 7177-86. PMID 8636155 DOI: 10.1074/Jbc.271.12.7177  1
1996 Kobertz WR, Essigmann JM. Total synthesis of a cis-syn 2-carbomethoxypsoralen furan-side thymidine monoadduct Journal of the American Chemical Society. 118: 7101-7107. DOI: 10.1021/Ja960511E  1
1995 Lipscomb LA, Peek ME, Morningstar ML, Verghis SM, Miller EM, Rich A, Essigmann JM, Williams LD. X-ray structure of a DNA decamer containing 7,8-dihydro-8-oxoguanine. Proceedings of the National Academy of Sciences of the United States of America. 92: 719-23. PMID 7846041 DOI: 10.1073/Pnas.92.3.719  1
1995 McGoldrick JP, Yeh YC, Solomon M, Essigmann JM, Lu AL. Characterization of a mammalian homolog of the Escherichia coli MutY mismatch repair protein. Molecular and Cellular Biology. 15: 989-96. PMID 7823963  1
1995 Mello JA, Lippard SJ, Essigmann JM. DNA adducts of cis-diamminedichloroplatinum(II) and its trans isomer inhibit RNA polymerase II differentially in vivo. Biochemistry. 34: 14783-91. PMID 7578087 DOI: 10.1021/Bi00045A020  1
1995 Yarema KJ, Lippard SJ, Essigmann JM. Mutagenic and genotoxic effects of DNA adducts formed by the anticancer drug cis-diamminedichloroplatinum(II). Nucleic Acids Research. 23: 4066-72. PMID 7479066 DOI: 10.1093/Nar/23.20.4066  1
1995 Yarema KJ, Essigmann JM. Evaluation of the Genetic Effects of Defined DNA Lesions Formed by DNA-Damaging Agents Methods. 7: 133-146. DOI: 10.1006/Meth.1995.1020  1
1994 Treiber DK, Zhai X, Jantzen HM, Essigmann JM. Cisplatin-DNA adducts are molecular decoys for the ribosomal RNA transcription factor hUBF (human upstream binding factor). Proceedings of the National Academy of Sciences of the United States of America. 91: 5672-6. PMID 8202546 DOI: 10.1073/Pnas.91.12.5672  1
1994 Yarema KJ, Wilson JM, Lippard SJ, Essigmann JM. Effects of DNA adduct structure and distribution on the mutagenicity and genotoxicity of two platinum anticancer drugs. Journal of Molecular Biology. 236: 1034-48. PMID 8120885 DOI: 10.1016/0022-2836(94)90010-8  1
1993 Essigmann JM, Wood ML. The relationship between the chemical structures and mutagenic specificities of the DNA lesions formed by chemical and physical mutagens. Toxicology Letters. 67: 29-39. PMID 8451766 DOI: 10.1016/0378-4274(93)90044-X  1
1993 Bradley LJ, Yarema KJ, Lippard SJ, Essigmann JM. Mutagenicity and genotoxicity of the major DNA adduct of the antitumor drug cis-diamminedichloroplatinum(II). Biochemistry. 32: 982-8. PMID 8422401 DOI: 10.1021/Bi00054A031  1
1993 Povey AC, Wilson VL, Weston A, Doan VT, Wood ML, Essigmann JM, Shields PG. Detection of oxidative damage by 32P-postlabelling: 8-hydroxydeoxyguanosine as a marker of exposure. Iarc Scientific Publications. 105-14. PMID 8225472  1
1992 Wood ML, Esteve A, Morningstar ML, Kuziemko GM, Essigmann JM. Genetic effects of oxidative DNA damage: comparative mutagenesis of 7,8-dihydro-8-oxoguanine and 7,8-dihydro-8-oxoadenine in Escherichia coli. Nucleic Acids Research. 20: 6023-32. PMID 1461734  1
1992 Treiber DK, Chen Z, Essigmann JM. An ultraviolet light-damaged DNA recognition protein absent in xeroderma pigmentosum group E cells binds selectively to pyrimidine (6-4) pyrimidone photoproducts. Nucleic Acids Research. 20: 5805-10. PMID 1454541  1
1992 Szymkowski DE, Yarema K, Essigmann JM, Lippard SJ, Wood RD. An intrastrand d(GpG) platinum crosslink in duplex M13 DNA is refractory to repair by human cell extracts. Proceedings of the National Academy of Sciences of the United States of America. 89: 10772-6. PMID 1438274 DOI: 10.1073/Pnas.89.22.10772  1
1992 Bruhn SL, Pil PM, Essigmann JM, Housman DE, Lippard SJ. Isolation and characterization of human cDNA clones encoding a high mobility group box protein that recognizes structural distortions to DNA caused by binding of the anticancer agent cisplatin. Proceedings of the National Academy of Sciences of the United States of America. 89: 2307-11. PMID 1372440 DOI: 10.1073/Pnas.89.6.2307  1
1992 Comess KM, Burstyn JN, Essigmann JM, Lippard SJ. Replication inhibition and translesion synthesis on templates containing site-specifically placed cis-diamminedichloroplatinum(II) DNA adducts. Biochemistry. 31: 3975-90. PMID 1314653 DOI: 10.1021/Bi00131A013  1
1991 Singer B, Essigmann JM. Site-specific mutagenesis: retrospective and prospective. Carcinogenesis. 12: 949-55. PMID 2044201  1
1991 Sassanfar M, Dosanjh MK, Essigmann JM, Samson L. Relative efficiencies of the bacterial, yeast, and human DNA methyltransferases for the repair of O6-methylguanine and O4-methylthymine. Suggestive evidence for O4-methylthymine repair by eukaryotic methyltransferases. The Journal of Biological Chemistry. 266: 2767-71. PMID 1993655  1
1991 Chaudhuri I, Essigmann JM. 3-Methyladenine mutagenesis under conditions of SOS induction in Escherichia coli. Carcinogenesis. 12: 2283-9. PMID 1747928 DOI: 10.1093/Carcin/12.12.2283  1
1990 Basu AK, Essigmann JM. Site-specifically alkylated oligodeoxynucleotides: probes for mutagenesis, DNA repair and the structural effects of DNA damage. Mutation Research. 233: 189-201. PMID 2233800 DOI: 10.1016/0027-5107(90)90162-W  1
1990 Wood ML, Dizdaroglu M, Gajewski E, Essigmann JM. Mechanistic studies of ionizing radiation and oxidative mutagenesis: genetic effects of a single 8-hydroxyguanine (7-hydro-8-oxoguanine) residue inserted at a unique site in a viral genome. Biochemistry. 29: 7024-32. PMID 2223758 DOI: 10.1021/Bi00482A011  1
1990 Heiger-Bernays WJ, Essigmann JM, Lippard SJ. Effect of the antitumor drug cis-diamminedichloroplatinum(II) and related platinum complexes on eukaryotic DNA replication. Biochemistry. 29: 8461-6. PMID 2174701 DOI: 10.1021/Bi00488A037  1
1990 Loechler EL, Benasutti M, Basu AK, Green CL, Essigmann JM. The role of carcinogen DNA adduct structure in the induction of mutations Progress in Clinical and Biological Research. 340: 51-60. PMID 2117761  1
1989 Ellison KS, Dogliotti E, Connors TD, Basu AK, Essigmann JM. Site-specific mutagenesis by O6-alkylguanines located in the chromosomes of mammalian cells: influence of the mammalian O6-alkylguanine-DNA alkyltransferase. Proceedings of the National Academy of Sciences of the United States of America. 86: 8620-4. PMID 2813414 DOI: 10.1073/Pnas.86.22.8620  1
1989 Singer B, Chavez F, Goodman MF, Essigmann JM, Dosanjh MK. Effect of 3' flanking neighbors on kinetics of pairing of dCTP or dTTP opposite O6-methylguanine in a defined primed oligonucleotide when Escherichia coli DNA polymerase I is used Proceedings of the National Academy of Sciences of the United States of America. 86: 8271-8274. PMID 2682644 DOI: 10.1073/Pnas.86.21.8271  1
1989 Basu AK, Loechler EL, Leadon SA, Essigmann JM. Genetic effects of thymine glycol: Site-specific mutagenesis and molecular modeling studies Proceedings of the National Academy of Sciences of the United States of America. 86: 7677-7681. PMID 2682618 DOI: 10.1073/Pnas.86.20.7677  1
1989 Couto LB, Chaudhuri I, Donahue BA, Demple B, Essigmann JM. Separation of the SOS-dependent and SOS-independent components of alkylating-agent mutagenesis Journal of Bacteriology. 171: 4170-4177. PMID 2666388 DOI: 10.1128/Jb.171.8.4170-4177.1989  1
1989 Essigmann JM, Basu AK, Loechler EL. Mutagenic specificity of alkylated and oxidized DNA bases as determined by site-specific mutagenesis Annali Dell'Istituto Superiore Di Sanita. 25: 155-161. PMID 2665597  1
1989 Ellison KS, Dogliotti E, Essigmann JM. Construction of a shuttle vector containing a single O6-methylguanine: a probe for mutagenesis in mammalian cells. Mutation Research. 220: 93-100. PMID 2538744 DOI: 10.1016/0165-1110(89)90014-6  1
1989 Toney JH, Donahue BA, Kellett PJ, Bruhn SL, Essigmann JM, Lippard SJ. Isolation of cDNAs encoding a human protein that binds selectively to DNA modified by the anticancer drug cis-diamminedichloroplatinum(II) Proceedings of the National Academy of Sciences of the United States of America. 86: 8328-32. PMID 2530581 DOI: 10.1073/Pnas.86.21.8328  1
1988 Wilson VL, Basu AK, Essigmann JM, Smith RA, Harris CC. O6-alkyldeoxyguanosine detection by 32P-postlabeling and nucleotide chromatographic analysis Cancer Research. 48: 2156-2161. PMID 3349485  1
1988 Naser LJ, Pinto AL, Lippard SJ, Essigmann JM. Chemical and biological studies of the major DNA adduct of cis-diamminedichloroplatinum(II), cis-[Pt(NH3)2{d(GpG)}], built into a specific site in a viral genome Biochemistry®. 27: 4357-4367. PMID 3166983 DOI: 10.1021/Bi00412A024  1
1988 Lasko DD, Harvey SC, Malaikal SB, Kadlubar FF, Essigmann JM. Specificity of mutagenesis by 4-aminobiphenyl. A possible role for N-(deoxyadenosin-8-yl)-4-aminobiphenyl as a premutational lesion. The Journal of Biological Chemistry. 263: 15429-35. PMID 3049608  1
1988 Basu AK, Essigmann JM. Site-specifically modified oligodeoxynucleotides as probes for the structural and biological effects of DNA-damaging agents Chemical Research in Toxicology. 1: 1-18. PMID 2979705 DOI: 10.1021/Tx00001A001  1
1987 Basu AK, Niedernhofer LJ, Essigmann JM. Deoxyhexanucleotide containing a vinyl chloride induced DNA lesion, 1,N6-ethenoadenine: Synthesis, physical characterization, and incorporation into a duplex bacteriophage M13 genome as part of an amber codon Biochemistry. 26: 5626-5635. PMID 3314993 DOI: 10.1021/Bi00392A007  1
1986 Scicchitano D, Jones RA, Kuzmich S, Gaffney B, Lasko DD, Essigmann JM, Pegg AE. Repair of oligodeoxynucleotides containing o-methylguanine by o-alkylguanine-dna-alkyltransferase Carcinogenesis. 7: 1383-1386. PMID 3731392 DOI: 10.1093/Carcin/7.8.1383  1
1986 Essigmann JM, Loechler EL, Green CL. Mutagenesis and repair of O6-substituted guanines Iarc Scientific Publications. 393-399. PMID 3539791  1
1986 Essigmann JM, Loechler EL, Green CL. Genetic toxicology of O6 methylguanine Progress in Clinical and Biological Research. 209: 433-440. PMID 3529107  1
1986 Pinto AL, Naser LJ, Essigmann JM, Lippard SJ. Site-specifically platinated DNA, a new probe of the biological activity of platinum anticancer drugs Journal of the American Chemical Society. 108: 7405-7407.  1
1985 Essigmann JM, Fowler KW, Green CL, Loechler EL. Extrachromosomal probes for mutagenesis by carcinogens: Studies on the mutagenic activity of O6-methylguanine built into a unique site in a viral genome Environmental Health Perspectives. 171-176. PMID 3910417 DOI: 10.1289/Ehp.8562171  1
1985 Rouet P, Essigmann JM. Possible role for thymine glycol in the selective inhibition of DNA synthesis on oxidized DNA templates Cancer Research. 45: 6113-6118. PMID 3904979  1
1984 Green CL, Loechler EL, Fowler KW, Essigmann JM. Construction and characterization of extrachromosomal probes for mutagenesis by carcinogens: Site-specific incorporation of O6-methylguanine into viral and plasmid genomes Proceedings of the National Academy of Sciences of the United States of America. 81: 13-17. PMID 6320161 DOI: 10.1073/Pnas.81.1.13  1
1984 Loechler EL, Green CL, Essigmann JM. In vivo mutagenesis by O6-methylguanine built into a unique site in a viral genome Proceedings of the National Academy of Sciences of the United States of America. 81: 6271-6275. PMID 6093094 DOI: 10.1073/Pnas.81.20.6271  1
1983 Essigmann JM, Green CL, Croy RG, Fowler KW, Büchi GH, Wogan GN. Interactions of aflatoxin B1 and alkylating agents with DNA: structural and functional studies. Cold Spring Harbor Symposia On Quantitative Biology. 47: 327-37. PMID 6407800 DOI: 10.1101/Sqb.1983.047.01.038  1
1983 Croy RG, Essigmann JM, Wogan GN. Aflatoxin B1: correlations of patterns of metabolism and DNA modification with biological effects. Basic Life Sciences. 24: 49-62. PMID 6407467 DOI: 10.1007/978-1-4684-4400-1_3  1
1982 Essigmann JM, Croy RG, Bennett RA, Wogan GN. Metabolic activation of aflatoxin B1: patterns of DNA adduct formation, removal, and excretion in relation to carcinogenesis. Drug Metabolism Reviews. 13: 581-602. PMID 6813091 DOI: 10.3109/03602538209011088  1
1982 Fowler KW, Büchi G, Essigmann JM. Synthesis and characterization of an oligonucleotide containing a carcinogen-modified base: O6-Methylguanine Journal of the American Chemical Society. 104: 1050-1054. DOI: 10.1021/Ja00368A023  1
1982 Green CL, Essigmann JM. Site-directed incorporation of a chemically synthesized oligonucleotide containing a carcinogen-modified base, O6-methylguanine into a bacterial plasmid genome Proceedings of the American Association For Cancer Research. No. 240.  1
1981 Bennett RA, Essigmann JM, Wogan GN. Excretion of an aflatoxin-guanine adduct in the urine of aflatoxin B1-treated rats. Cancer Research. 41: 650-4. PMID 6778611  1
1980 Essigmann JM, Donahue PR, Story DL, Wogan GN, Brunengraber H. Use of the isolated perfused rat liver to study carcinogen-DNA adduct formation from aflatoxin B1 and sterigmatocystin. Cancer Research. 40: 4085-91. PMID 6781740  1
1980 Fox JG, Donahue PR, Essigmann JM. Efficacy of inactivation of representative chemical carcinogens utilizing commercial alkaline and acidic cage washing compounds Journal of Environmental Pathology and Toxicology. 4: 97-105. PMID 6777448  1
1980 Autrup H, Schwartz RD, Essigmann JM. Metabolism of aflatoxin B1, benzo[a]pyrene, and 1,2-dimethylhydrazine by cultured rat and human colon Teratogenesis Carcinogenesis and Mutagenesis. 1: 3-13. PMID 6119799 DOI: 10.1002/Tcm.1770010103  1
1979 Autrup H, Essigmann JM, Croy RG, Trump BF, Wogan GN, Harris CC. Metabolism of aflatoxin B1 and identification of the major aflatoxin B1-DNA adducts formed in cultured human bronchus and colon. Cancer Research. 39: 694-8. PMID 427755  1
1979 Stark AA, Essigmann JM, Demain AL, Skopek TR, Wogan GN. Aflatoxin B1 mutagenesis, DNA binding, and adduct formation in Salmonella typhimurium. Proceedings of the National Academy of Sciences of the United States of America. 76: 1343-7. PMID 375236  1
1979 Essigmann JM, Barker LJ, Fowler KW, Francisco MA, Reinhold VN, Wogan GN. Sterigmatocystin-DNA interactions: identification of a major adduct formed after metabolic activation in vitro. Proceedings of the National Academy of Sciences of the United States of America. 76: 179-83. PMID 284330 DOI: 10.1073/Pnas.76.1.179  1
1979 Autrup H, Essigmann JM, Harris CC. Metabolism of chemical carcinogens by cultured colon Federation Proceedings. 38: No. 4472.  1
1979 Autrup H, Essigmann JM, Trump BF. Metabolism of aflatoxin B1 by cultured human tissues Proceedings of the American Association For Cancer Research. No. 10.  1
1978 Croy RG, Essigmann JM, Reinhold VN, Wogan GN. Identification of the principal aflatoxin B1-DNA adduct formed in vivo in rat liver. Proceedings of the National Academy of Sciences of the United States of America. 75: 1745-9. PMID 273905 DOI: 10.1073/Pnas.75.4.1745  1
1978 Croy RG, Essigmann JM, Reinhold VN, Wogan GN. Identification of the principal aflatoxin B1 DNA adduct formed in vivo in rat liver Proceedings of the American Association For Cancer Research. No. 761.  1
1977 Essigmann JM, Busby WF, Wogan GN. Quantitative determination of transfer RNA base composition using high-pressure liquid chromatography. Analytical Biochemistry. 81: 384-94. PMID 907101 DOI: 10.1016/0003-2697(77)90709-6  1
1977 Rosiello AP, Essigmann JM, Wogan GN. Rapid and accurate determination of the median lethal dose (Ld50) and its error with a small computer Journal of Toxicology and Environmental Health. 3: 797-809. PMID 599579 DOI: 10.1080/15287397709529614  1
1977 Essigmann JM, Croy RG, Nadzan AM, Busby WF, Reinhold VN, Büchi G, Wogan GN. Structural identification of the major DNA adduct formed by aflatoxin B1 in vitro. Proceedings of the National Academy of Sciences of the United States of America. 74: 1870-4. PMID 266709 DOI: 10.1073/Pnas.74.5.1870  1
1975 Essigmann JM, Catsimpoolas N. Simple derivative mode detector for liquid chromatography Journal of Chromatography A. 103: 7-13. DOI: 10.1016/S0021-9673(00)83796-6  1
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