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Peter L. Sazani, Ph.D. - Publications

Affiliations: 
2002 University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Pharmacology
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24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Echigoya Y, Nakamura A, Nagata T, Urasawa N, Lim KR, Trieu N, Panesar D, Kuraoka M, Moulton HM, Saito T, Aoki Y, Iversen P, Sazani P, Kole R, Maruyama R, et al. Effects of systemic multiexon skipping with peptide-conjugated morpholinos in the heart of a dog model of Duchenne muscular dystrophy. Proceedings of the National Academy of Sciences of the United States of America. PMID 28373570 DOI: 10.1073/Pnas.1613203114  0.607
2016 Carver MP, Charleston JS, Shanks C, Zhang J, Mense M, Sharma AK, Kaur H, Sazani P. Toxicological Characterization of Exon Skipping Phosphorodiamidate Morpholino Oligomers (PMOs) in Non-human Primates. Journal of Neuromuscular Diseases. 3: 381-393. PMID 27854228 DOI: 10.3233/Jnd-160157  0.33
2015 Heald AE, Charleston JS, Iversen PL, Warren TK, Saoud JB, Al-Ibrahim M, Wells J, Warfield KL, Swenson DL, Welch LS, Sazani P, Wong M, Berry D, Kaye EM, Bavari S. AVI-7288 for Marburg Virus in Nonhuman Primates and Humans. The New England Journal of Medicine. 373: 339-48. PMID 26200980 DOI: 10.1056/Nejmoa1410345  0.315
2013 Wan J, Bauman JA, Graziewicz MA, Sazani P, Kole R. Oligonucleotide therapeutics in cancer. Cancer Treatment and Research. 158: 213-33. PMID 24222360 DOI: 10.1007/978-3-642-31659-3_9  0.706
2013 Wan J, Bauman JA, Graziewicz MA, Sazani P, Kole R. Oligonucleotide therapeutics in cancer Cancer Treatment and Research. 158: 213-233. DOI: 10.1007/978-3-642-31659-3_9  0.558
2011 Sazani P, Ness KP, Weller DL, Poage D, Nelson K, Shrewsbury AS. Chemical and mechanistic toxicology evaluation of exon skipping phosphorodiamidate morpholino oligomers in mdx mice. International Journal of Toxicology. 30: 322-33. PMID 21540335 DOI: 10.1177/1091581811403504  0.302
2010 Sazani P, Weller DL, Shrewsbury SB. Safety pharmacology and genotoxicity evaluation of AVI-4658. International Journal of Toxicology. 29: 143-56. PMID 20110565 DOI: 10.1177/1091581809359206  0.32
2010 Jearawiriyapaisarn N, Moulton HM, Sazani P, Kole R, Willis MS. Long-term improvement in mdx cardiomyopathy after therapy with peptide-conjugated morpholino oligomers. Cardiovascular Research. 85: 444-53. PMID 19815563 DOI: 10.1093/Cvr/Cvp335  0.596
2009 Moulton HM, Wu B, Jearawiriyapaisarn N, Sazani P, Lu QL, Kole R. Peptide-morpholino conjugate: a promising therapeutic for Duchenne muscular dystrophy. Annals of the New York Academy of Sciences. 1175: 55-60. PMID 19796077 DOI: 10.1111/J.1749-6632.2009.04976.X  0.601
2009 Wan J, Sazani P, Kole R. Modification of HER2 pre-mRNA alternative splicing and its effects on breast cancer cells. International Journal of Cancer. Journal International Du Cancer. 124: 772-7. PMID 19035464 DOI: 10.1002/Ijc.24052  0.653
2008 Graziewicz MA, Tarrant TK, Buckley B, Roberts J, Fulton L, Hansen H, Ørum H, Kole R, Sazani P. An Endogenous TNF-α Antagonist Induced by Splice-switching Oligonucleotides Reduces Inflammation in Hepatitis and Arthritis Mouse Models. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1316-1322. PMID 28178484 DOI: 10.1038/Mt.2008.85  0.573
2008 Jearawiriyapaisarn N, Moulton HM, Buckley B, Roberts J, Sazani P, Fucharoen S, Iversen PL, Kole R. Sustained dystrophin expression induced by peptide-conjugated morpholino oligomers in the muscles of mdx mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1624-9. PMID 18545222 DOI: 10.1038/Mt.2008.120  0.646
2008 Graziewicz MA, Tarrant TK, Buckley B, Roberts J, Fulton L, Hansen H, Ørum H, Kole R, Sazani P. An endogenous TNF-alpha antagonist induced by splice-switching oligonucleotides reduces inflammation in hepatitis and arthritis mouse models. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1316-22. PMID 18461057 DOI: 10.1038/mt.2008.85  0.567
2006 Roberts J, Palma E, Sazani P, Ørum H, Cho M, Kole R. Efficient and persistent splice switching by systemically delivered LNA oligonucleotides in mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 14: 471-5. PMID 16854630 DOI: 10.1016/J.Ymthe.2006.05.017  0.624
2003 Sazani P, Astriab-Fischer A, Kole R. Effects of base modifications on antisense properties of 2'-O-methoxyethyl and PNA oligonucleotides. Antisense & Nucleic Acid Drug Development. 13: 119-28. PMID 12954112 DOI: 10.1089/108729003768247583  0.63
2003 Sazani P, Kole R. Therapeutic potential of antisense oligonucleotides as modulators of alternative splicing. The Journal of Clinical Investigation. 112: 481-6. PMID 12925686 DOI: 10.1172/Jci19547  0.691
2003 Vacek M, Sazani P, Kole R. Antisense-mediated redirection of mRNA splicing Cellular and Molecular Life Sciences. 60: 825-833. PMID 12827272 DOI: 10.1007/S00018-003-3042-7  0.712
2002 McAllister K, Sazani P, Adam M, Cho MJ, Rubinstein M, Samulski RJ, DeSimone JM. Polymeric nanogels produced via inverse microemulsion polymerization as potential gene and antisense delivery agents. Journal of the American Chemical Society. 124: 15198-207. PMID 12487595 DOI: 10.1021/Ja027759Q  0.314
2002 Sazani P, Vacek MM, Kole R. Short-term and long-term modulation of gene expression by antisense therapeutics. Current Opinion in Biotechnology. 13: 468-72. PMID 12459339 DOI: 10.1016/S0958-1669(02)00366-X  0.699
2002 Sazani P, Gemignani F, Kang SH, Maier MA, Manoharan M, Persmark M, Bortner D, Kole R. Systemically delivered antisense oligomers upregulate gene expression in mouse tissues. Nature Biotechnology. 20: 1228-33. PMID 12426578 DOI: 10.1038/Nbt759  0.666
2002 Gemignani F, Sazani P, Morcos P, Kole R. Temperature-dependent splicing of beta-globin pre-mRNA. Nucleic Acids Research. 30: 4592-8. PMID 12409448 DOI: 10.1093/Nar/Gkf607  0.621
2001 Mercatante DR, Sazani P, Kole R. Modification of alternative splicing by antisense oligonucleotides as a potential chemotherapy for cancer and other diseases. Current Cancer Drug Targets. 1: 211-30. PMID 12188880  0.732
2001 Sazani P, Kang SH, Maier MA, Wei C, Dillman J, Summerton J, Manoharan M, Kole R. Nuclear antisense effects of neutral, anionic and cationic oligonucleotide analogs Nucleic Acids Research. 29: 3965-3974. PMID 11574678 DOI: 10.1093/Nar/29.19.3965  0.622
2000 Yoo H, Sazani P, Juliano RL. PAMAM dendrimers as delivery agents for antisense oligonucleotides. Pharmaceutical Research. 16: 1799-804. PMID 10644065 DOI: 10.1023/A:1018926605871  0.312
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