Jean Costentin, MD - Publications

Affiliations: 
laboratoire de neuropsychopharmacologie expérimentale Université de Rouen 

223 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Costentin J. [Neurobiology of endocannabinoids and central effects of tetrahydrocannabinol contained in indian hemp]. Bulletin De L'AcadéMie Nationale De MéDecine. 198: 527-38; discussion 5. PMID 26427295 DOI: 10.1016/S0001-4079(19)31320-2  0.334
2015 Pelloux Y, Costentin J, Duterte-Boucher D. Differential involvement of anxiety and novelty preference levels on oral ethanol consumption in rats. Psychopharmacology. 232: 2711-21. PMID 25761842 DOI: 10.1007/S00213-015-3910-5  0.76
2015 Viana AF, Costentin J, do Rego JC, Rates SMK. G-protein activation revealed by [35S]-GTPγS binding assay is involved on the antidepressant-like effect of Hypericum caprifoliatum and Hypericum polyanthemum cyclohexane extracts Brazilian Journal of Pharmacognosy. 25: 387-394. DOI: 10.1016/J.Bjp.2015.06.008  0.365
2013 Le Maître E, Dourmap N, Vilpoux C, Leborgne R, Janin F, Bonnet JJ, Costentin J, Leroux-Nicollet I. Acute and subchronic treatments with selective serotonin reuptake inhibitors increase Nociceptin/Orphanin FQ (NOP) receptor density in the rat dorsal raphe nucleus; interactions between nociceptin/NOP system and serotonin. Brain Research. 1520: 51-60. PMID 23669068 DOI: 10.1016/J.Brainres.2013.05.005  0.386
2012 Neveu C, Lefranc B, Tasseau O, Do-Rego JC, Bourmaud A, Chan P, Bauchat P, Le Marec O, Chuquet J, Guilhaudis L, Boutin JA, Ségalas-Milazzo I, Costentin J, Vaudry H, Baudy-Floc'h M, et al. Rational design of a low molecular weight, stable, potent, and long-lasting GPR103 aza-β3-pseudopeptide agonist. Journal of Medicinal Chemistry. 55: 7516-24. PMID 22800498 DOI: 10.1021/Jm300507D  0.304
2012 Billet F, Costentin J, Dourmap N. Influence of corticostriatal δ-opioid receptors on abnormal involuntary movements induced by L-DOPA in hemiparkinsonian rats. Experimental Neurology. 236: 339-50. PMID 22575599 DOI: 10.1016/J.Expneurol.2012.04.017  0.411
2012 Stein AC, Viana AF, Müller LG, Nunes JM, Stolz ED, Do Rego JC, Costentin J, von Poser GL, Rates SM. Uliginosin B, a phloroglucinol derivative from Hypericum polyanthemum: a promising new molecular pattern for the development of antidepressant drugs. Behavioural Brain Research. 228: 66-73. PMID 22155486 DOI: 10.1016/J.Bbr.2011.11.031  0.389
2011 Cravezic A, Fichna J, Gach K, Wyrebska A, Perlikowska R, Costentin J, Bonnet JJ, Janecka A, do Rego JC. Effect of potent endomorphin degradation blockers on analgesic and antidepressant-like responses in mice. Neuropharmacology. 61: 1229-38. PMID 21803061 DOI: 10.1016/J.Neuropharm.2011.07.021  0.367
2009 Costentin J. [A new approach to antischizophrenic therapeutics: D2 dopamine receptor partial agonists]. Annales Pharmaceutiques Franã§Aises. 67: 310-9. PMID 19695367 DOI: 10.1016/J.Pharma.2009.05.004  0.42
2009 Bohn P, Le Fur N, Hagues G, Costentin J, Torquet N, Papamicaël C, Marsais F, Levacher V. Rational design of central selective acetylcholinesterase inhibitors by means of a "bio-oxidisable prodrug" strategy. Organic & Biomolecular Chemistry. 7: 2612-8. PMID 19503937 DOI: 10.1039/B903041G  0.729
2009 Costentin J. [A new pharmacological strategy for schizophrenia: the partial agonists of D2 dopaminergic receptors. The principle characteristics of aripiprazole]. L'Encã©Phale. 35: 66-72. PMID 19250996 DOI: 10.1016/j.encep.2008.12.001  0.303
2009 Pelloux Y, Costentin J, Duterte-Boucher D. Anxiety increases the place conditioning induced by cocaine in rats. Behavioural Brain Research. 197: 311-6. PMID 18793676 DOI: 10.1016/J.Bbr.2008.08.029  0.786
2009 Mounien L, Do Rego JC, Bizet P, Boutelet I, Gourcerol G, Fournier A, Brabet P, Costentin J, Vaudry H, Jégou S. Pituitary adenylate cyclase-activating polypeptide inhibits food intake in mice through activation of the hypothalamic melanocortin system. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 424-35. PMID 18536705 DOI: 10.1038/Npp.2008.73  0.317
2008 Costentin J. [Neuropsychopharmacology of delta-9-tetrahydrocannabinol]. Annales Pharmaceutiques Franã§Aises. 66: 219-31. PMID 18847570 DOI: 10.1016/J.Pharma.2008.07.003  0.332
2008 El Yacoubi M, Ledent C, Parmentier M, Costentin J, Vaugeois JM. Evidence for the involvement of the adenosine A(2A) receptor in the lowered susceptibility to pentylenetetrazol-induced seizures produced in mice by long-term treatment with caffeine. Neuropharmacology. 55: 35-40. PMID 18486156 DOI: 10.1016/J.Neuropharm.2008.04.007  0.305
2008 Hagues G, Costentin J, Duterte-Boucher D. Locomotor effects of morphine or alcohol in mice after a repeated treatment with the cannabinoid agonist HU 210. European Journal of Pharmacology. 586: 197-204. PMID 18400220 DOI: 10.1016/J.Ejphar.2008.02.062  0.754
2008 Viana A, Rates S, Naudin B, Janin F, Costentin J, do Rego JC. Effects of acute or 3-day treatments of Hypericum caprifoliatum Cham. & Schltdt. (Guttiferae) extract or of two established antidepressants on basal and stress-induced increase in serum and brain corticosterone levels. Journal of Psychopharmacology (Oxford, England). 22: 681-90. PMID 18308787 DOI: 10.1177/0269881107082898  0.335
2008 Fichna J, do-Rego JC, Chung NN, Costentin J, Schiller PW, Janecka A. [Dmt1, d-1-Nal3]morphiceptin, a novel opioid peptide analog with high analgesic activity. Peptides. 29: 633-8. PMID 18234394 DOI: 10.1016/J.Peptides.2007.12.005  0.353
2008 Fichna J, do-Rego JC, Janecki T, Staniszewska R, Poels J, Broeck JV, Costentin J, Schiller PW, Janecka A. Novel highly potent mu-opioid receptor antagonist based on endomorphin-2 structure. Bioorganic & Medicinal Chemistry Letters. 18: 1350-3. PMID 18207400 DOI: 10.1016/J.Bmcl.2008.01.009  0.347
2008 Torquet N, Hagues G, Costentin J. The reduction in electric footshocks perception interferes with the amnesic effect of scopolamine. Behavioural Brain Research. 188: 238-40. PMID 18160109 DOI: 10.1016/J.Bbr.2007.11.006  0.743
2007 do Rego JC, Benkiki N, Chosson E, Kabouche Z, Seguin E, Costentin J. Antidepressant-like effect of hyperfoliatin, a polyisoprenylated phloroglucinol derivative from Hypericum perfoliatum (Clusiaceae) is associated with an inhibition of neuronal monoamines uptake. European Journal of Pharmacology. 569: 197-203. PMID 17574234 DOI: 10.1016/J.Ejphar.2007.05.008  0.398
2007 Fichna J, Janecka A, Costentin J, Do Rego JC. The endomorphin system and its evolving neurophysiological role. Pharmacological Reviews. 59: 88-123. PMID 17329549 DOI: 10.1124/Pr.59.1.3  0.3
2007 Bredeloux P, Dubuc I, Costentin J. Comparisons between bupropion and dexamphetamine in a range of in vivo tests exploring dopaminergic transmission. British Journal of Pharmacology. 150: 711-9. PMID 17293887 DOI: 10.1038/Sj.Bjp.0707151  0.491
2007 Fichna J, do-Rego JC, Chung NN, Lemieux C, Schiller PW, Poels J, Broeck JV, Costentin J, Janecka A. Synthesis and characterization of potent and selective mu-opioid receptor antagonists, [Dmt(1), D-2-Nal(4)]endomorphin-1 (Antanal-1) and [Dmt(1), D-2-Nal(4)]endomorphin-2 (Antanal-2). Journal of Medicinal Chemistry. 50: 512-20. PMID 17266203 DOI: 10.1021/Jm060998U  0.344
2007 Hagues G, Costentin J, Duterte-Boucher D. Modulation of morphine and alcohol motor stimulant effects by cannabinoid receptors ligands. Behavioural Brain Research. 178: 274-82. PMID 17254644 DOI: 10.1016/J.Bbr.2007.01.001  0.746
2007 do Rego JC, Orta MH, Leprince J, Tonon MC, Vaudry H, Costentin J. Pharmacological characterization of the receptor mediating the anorexigenic action of the octadecaneuropeptide: evidence for an endozepinergic tone regulating food intake. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 1641-8. PMID 17151595 DOI: 10.1038/Sj.Npp.1301280  0.363
2007 Fichna J, Janecka A, Piestrzeniewicz M, Costentin J, do Rego JC. Antidepressant-like effect of endomorphin-1 and endomorphin-2 in mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 813-21. PMID 16823383 DOI: 10.1111/J.1742-4658.2006.05268.X  0.37
2006 Viana AF, do Rego JC, Munari L, Dourmap N, Heckler AP, Costa TD, von Poser GL, Costentin J, Rates SM. Hypericum caprifoliatum (Guttiferae) Cham. & Schltdl.: a species native to South Brazil with antidepressant-like activity. Fundamental & Clinical Pharmacology. 20: 507-14. PMID 17109644 DOI: 10.1111/J.1472-8206.2006.00440.X  0.403
2006 Bredeloux P, Costentin J, Dubuc I. Interactions between NTS2 neurotensin and opioid receptors on two nociceptive responses assessed on the hot plate test in mice. Behavioural Brain Research. 175: 399-407. PMID 17074405 DOI: 10.1016/J.Bbr.2006.09.016  0.407
2006 Fichna J, Janecka A, Bailly L, Marsais F, Costentin J, do Rego JC. In vitro characterization of novel peptide inhibitors of endomorphin-degrading enzymes in the rat brain. Chemical Biology & Drug Design. 68: 173-5. PMID 17062015 DOI: 10.1111/J.1747-0285.2006.00425.X  0.344
2006 Le Maître E, Daubeuf F, Duterte-Boucher D, Costentin J, Leroux-Nicollet I. Coupling of ORL1 (NOP) receptor to G proteins is decreased in the nucleus accumbens of anxious relative to non-anxious mice. Brain Research. 1110: 144-9. PMID 16860781 DOI: 10.1016/J.Brainres.2006.06.074  0.737
2006 Pelloux Y, Costentin J, Duterte-Boucher D. Novelty preference predicts place preference conditioning to morphine and its oral consumption in rats. Pharmacology, Biochemistry, and Behavior. 84: 43-50. PMID 16733065 DOI: 10.1016/J.Pbb.2006.04.004  0.791
2006 Fichna J, do-Rego JC, Kosson P, Schiller PW, Costentin J, Janecka A. [(35)S]GTPgammaS binding stimulated by endomorphin-2 and morphiceptin analogs. Biochemical and Biophysical Research Communications. 345: 162-8. PMID 16677613 DOI: 10.1016/J.Bbrc.2006.04.079  0.337
2006 El Yacoubi M, Coupé B, Gabriel C, Mocaër E, Costentin J, Vaugeois J. P.2.d.021 Chronic agomelatine and fluoxetine treatments induce antidepressant effects in H/Rouen mice, a new genetic mouse model of depression European Neuropsychopharmacology. 16: S344. DOI: 10.1016/S0924-977X(06)70392-3  0.315
2005 Janecka A, Fichna J, Kruszynski R, Sasaki Y, Ambo A, Costentin J, do-Rego JC. Synthesis and antinociceptive activity of cyclic endomorphin-2 and morphiceptin analogs. Biochemical Pharmacology. 71: 188-95. PMID 16288997 DOI: 10.1016/J.Bcp.2005.10.018  0.358
2005 Do-Rego JC, Chatenet D, Orta MH, Naudin B, Le Cudennec C, Leprince J, Scalbert E, Vaudry H, Costentin J. Behavioral effects of urotensin-II centrally administered in mice. Psychopharmacology. 183: 103-17. PMID 16160878 DOI: 10.1007/S00213-005-0140-2  0.338
2005 Kruszynski R, Fichna J, do-Rego JC, Janecki T, Kosson P, Pakulska W, Costentin J, Janecka A. Synthesis and biological activity of N-methylated analogs of endomorphin-2. Bioorganic & Medicinal Chemistry. 13: 6713-7. PMID 16143536 DOI: 10.1016/J.Bmc.2005.07.051  0.361
2005 Suaudeau C, do-Rego JC, Costentin J. Modifications in avoidance reactions of mice, on a second exposure to the hot plate, resist to various amnesia-inducing treatments. Brain Research. Cognitive Brain Research. 25: 339-47. PMID 16051473 DOI: 10.1016/J.Cogbrainres.2005.06.007  0.32
2005 Viana A, do Rego JC, von Poser G, Ferraz A, Heckler AP, Costentin J, Kuze Rates SM. The antidepressant-like effect of Hypericum caprifoliatum Cham & Schlecht (Guttiferae) on forced swimming test results from an inhibition of neuronal monoamine uptake. Neuropharmacology. 49: 1042-52. PMID 16040063 DOI: 10.1016/J.Neuropharm.2005.06.002  0.479
2005 Vautrin S, Pelloux Y, Costentin J. Preference for caffeine appears earlier in non-anxious than in anxious mice. Neuroscience Letters. 386: 94-8. PMID 16039049 DOI: 10.1016/J.Neulet.2005.05.071  0.701
2005 Le Maître E, Vilpoux C, Costentin J, Leroux-Nicollet I. Opioid receptor-like 1 (NOP) receptors in the rat dorsal raphe nucleus: evidence for localization on serotoninergic neurons and functional adaptation after 5,7-dihydroxytryptamine lesion. Journal of Neuroscience Research. 81: 488-96. PMID 15948180 DOI: 10.1002/Jnr.20571  0.353
2005 Chartrel N, Bruzzone F, Dujardin C, Leprince J, Tollemer H, Anouar Y, Vallarino M, Costentin J, Vaudry H. Identification of 26RFa from frog brain: a novel hypothalamic neuropeptide with orexigenic activity in mammals. Annals of the New York Academy of Sciences. 1040: 80-3. PMID 15891009 DOI: 10.1196/Annals.1327.009  0.324
2005 Fichna J, do-Rego JC, Mirowski M, Costentin J, Janecka A. Binding of endomorphin-2 to mu-opioid receptors in experimental mouse mammary adenocarcinoma. The Journal of Peptide Research : Official Journal of the American Peptide Society. 65: 459-64. PMID 15813894 DOI: 10.1111/J.1399-3011.2005.00236.X  0.352
2005 Pelloux Y, Hagues G, Costentin J, Duterte-Boucher D. Helplessness in the tail suspension test is associated with an increase in ethanol intake and its rewarding effect in female mice. Alcoholism, Clinical and Experimental Research. 29: 378-88. PMID 15770113 DOI: 10.1097/01.Alc.0000156123.10298.Fa  0.776
2005 Costentin J, Marçais H, Protais P, Schwartz JC. Tolerance to hypokinesia elicited by dopamine agonists in mice: hyposensitization of autoreceptors? Life Sciences. 20: 883-6. PMID 15714774 DOI: 10.1016/0024-3205(77)90041-8  0.599
2005 Fichna J, do-Rego JC, Kosson P, Costentin J, Janecka A. Characterization of antinociceptive activity of novel endomorphin-2 and morphiceptin analogs modified in the third position. Biochemical Pharmacology. 69: 179-85. PMID 15588726 DOI: 10.1016/J.Bcp.2004.09.011  0.314
2004 Billet F, Dourmap N, Costentin J. Involvement of corticostriatal glutamatergic terminals in striatal dopamine release elicited by stimulation of delta-opioid receptors. The European Journal of Neuroscience. 20: 2629-38. PMID 15548206 DOI: 10.1111/J.1460-9568.2004.03723.X  0.423
2004 Vaugeois JM, El Yacoubi M, Costentin J. [Comments on an animal model of depression]. Annales Pharmaceutiques Franã§Aises. 62: 332-42. PMID 15314581 DOI: 10.1016/S0003-4509(04)94322-2  0.32
2004 Bonnet JJ, Legros H, Janin F, Dourmap N, Costentin J. [Assessment of the in vitro and in vivo toxicity of 3,4-dihydroxyphenylacetaldehyde (DOPAL)]. Annales Pharmaceutiques Franã§Aises. 62: 323-31. PMID 15314580 DOI: 10.1016/S0003-4509(04)94321-0  0.413
2004 Fichna J, do-Rego JC, Costentin J, Chung NN, Schiller PW, Kosson P, Janecka A. Opioid receptor binding and in vivo antinociceptive activity of position 3-substituted morphiceptin analogs. Biochemical and Biophysical Research Communications. 320: 531-6. PMID 15219861 DOI: 10.1016/J.Bbrc.2004.05.202  0.347
2004 Costentin J. [Physiological and neurobiological elements of food intake]. Annales Pharmaceutiques Franã§Aises. 62: 92-102. PMID 15107726 DOI: 10.1016/S0003-4509(04)94287-3  0.343
2004 Legros H, Dingeval MG, Janin F, Costentin J, Bonnet JJ. Toxicity of a treatment associating dopamine and disulfiram for catecholaminergic neuroblastoma SH-SY5Y cells: relationships with 3,4-dihydroxyphenylacetaldehyde formation. Neurotoxicology. 25: 365-75. PMID 15019299 DOI: 10.1016/S0161-813X(03)00148-7  0.345
2004 Legros H, Janin F, Dourmap N, Bonnet JJ, Costentin J. Semi-chronic increase in striatal level of 3,4-dihydroxyphenylacetaldehyde does not result in alteration of nigrostriatal dopaminergic neurones. Journal of Neuroscience Research. 75: 429-35. PMID 14743456 DOI: 10.1002/Jnr.10880  0.409
2004 Pelloux Y, Costentin J, Duterte-Boucher D. Differential effects of novelty exposure on place preference conditioning to amphetamine and its oral consumption. Psychopharmacology. 171: 277-85. PMID 12961061 DOI: 10.1007/S00213-003-1584-X  0.795
2003 El Yacoubi M, Costentin J, Vaugeois JM. Adenosine A2A receptors and depression. Neurology. 61: S82-7. PMID 14663017 DOI: 10.1212/01.Wnl.0000095220.87550.F6  0.413
2003 El Yacoubi M, Ledent C, Parmentier M, Costentin J, Vaugeois JM. Caffeine reduces hypnotic effects of alcohol through adenosine A2A receptor blockade. Neuropharmacology. 45: 977-85. PMID 14573390 DOI: 10.1016/S0028-3908(03)00254-5  0.343
2003 Cleren C, Naudin B, Costentin J. Apparent opposite effects of tetrabenazine and reserpine on the toxic effects of 1-methyl-4-phenylpyridinium or 6-hydroxydopamine on nigro-striatal dopaminergic neurons. Brain Research. 989: 187-95. PMID 14556940 DOI: 10.1016/S0006-8993(03)03333-X  0.394
2003 El Yacoubi M, Bouali S, Popa D, Naudon L, Leroux-Nicollet I, Hamon M, Costentin J, Adrien J, Vaugeois JM. Behavioral, neurochemical, and electrophysiological characterization of a genetic mouse model of depression. Proceedings of the National Academy of Sciences of the United States of America. 100: 6227-32. PMID 12732720 DOI: 10.1073/Pnas.1034823100  0.321
2002 Vilpoux C, Carpentier C, Leroux-Nicollet I, Naudon L, Costentin J. Differential effects of chronic antidepressant treatments on micro- and delta-opioid receptors in rat brain. European Journal of Pharmacology. 443: 85-93. PMID 12044796 DOI: 10.1016/S0014-2999(02)01585-6  0.358
2002 Naudon L, El Yacoubi M, Vaugeois JM, Leroux-Nicollet I, Costentin J. A chronic treatment with fluoxetine decreases 5-HT(1A) receptors labeling in mice selected as a genetic model of helplessness. Brain Research. 936: 68-75. PMID 11988231 DOI: 10.1016/S0006-8993(02)02548-9  0.36
2002 Vilpoux C, Naudon L, Costentin J, Leroux-Nicollet I. Chronic paroxetine increases [3H]nociceptin binding in rat dorsal raphe nucleus. Neuroreport. 13: 111-4. PMID 11924870 DOI: 10.1097/00001756-200201210-00026  0.371
2002 Do-Rego JC, Suaudeau C, Chapouthier G, Costentin J. Mouse lines differing in sensitivity to beta-CCM differ in tasks used for testing antidepressants. Pharmacology, Biochemistry, and Behavior. 72: 411-6. PMID 11900813 DOI: 10.1016/S0091-3057(01)00761-4  0.358
2002 El Yacoubi M, Ledent C, Parmentier M, Costentin J, Vaugeois J. Long-term treatment with caffeine decreases the vulnerability to pentylenetetrazol-induced seizures in mice. Evidence for a contribution of A2A receptors obtained using knockout mice European Neuropsychopharmacology. 12: 435-436. DOI: 10.1016/S0924-977X(02)80762-3  0.326
2001 Leprince J, Oulyadi H, Vaudry D, Masmoudi O, Gandolfo P, Patte C, Costentin J, Fauchère JL, Davoust D, Vaudry H, Tonon MC. Synthesis, conformational analysis and biological activity of cyclic analogs of the octadecaneuropeptide ODN. Design of a potent endozepine antagonist. European Journal of Biochemistry / Febs. 268: 6045-57. PMID 11732998 DOI: 10.1046/J.0014-2956.2001.02533.X  0.31
2001 El Yacoubi M, Ledent C, Parmentier M, Ongini E, Costentin J, Vaugeois JM. In vivo labelling of the adenosine A2A receptor in mouse brain using the selective antagonist [3H]SCH 58261. The European Journal of Neuroscience. 14: 1567-70. PMID 11722618 DOI: 10.1046/J.0953-816X.2001.01771.X  0.42
2001 El Yacoubi M, Ledent C, Parmentier M, Bertorelli R, Ongini E, Costentin J, Vaugeois JM. Adenosine A2A receptor antagonists are potential antidepressants: evidence based on pharmacology and A2A receptor knockout mice. British Journal of Pharmacology. 134: 68-77. PMID 11522598 DOI: 10.1038/Sj.Bjp.0704240  0.42
2001 Naudon L, Leroux-Nicollet I, Boulay D, Costentin J. Decreased densities of dopamine and serotonin transporters and of vesicular monoamine transporter 2 in severely kainic acid lesioned subregions of the striatum. Journal of Neural Transmission (Vienna, Austria : 1996). 108: 431-44. PMID 11475010 DOI: 10.1007/S007020170064  0.71
2001 Syringas M, Janin F, Giros B, Costentin J, Bonnet JJ. Involvement of the NH2 terminal domain of catecholamine transporters in the Na(2+) and Cl(-)-dependence of a [3H]-dopamine uptake. British Journal of Pharmacology. 133: 387-94. PMID 11375255 DOI: 10.1038/Sj.Bjp.0704097  0.531
2001 El Yacoubi M, Ledent C, Parmentier M, Costentin J, Vaugeois JM. Adenosine A2A receptor knockout mice are partially protected against drug-induced catalepsy. Neuroreport. 12: 983-6. PMID 11303773 DOI: 10.1097/00001756-200104170-00024  0.466
2001 Asselin ML, Dubuc I, Coquerel A, Costentin J. Localization of neurotensin NTS2 receptors in rat brain, using. Neuroreport. 12: 1087-91. PMID 11303751 DOI: 10.1097/00001756-200104170-00044  0.307
2001 Tidjane Corera A, Do-Régo JC, Costentin J, Bonnet JJ. Differential sensitivity to NaCl for inhibitors and substrates that recognize mutually exclusive binding sites on the neuronal transporter of dopamine in rat striatal membranes. Neuroscience Research. 39: 319-25. PMID 11248372 DOI: 10.1016/S0168-0102(00)00230-3  0.351
2001 de Mateos-Verchere JG, Leprince J, Tonon MC, Vaudry H, Costentin J. The octadecaneuropeptide [diazepam-binding inhibitor (33-50)] exerts potent anorexigenic effects in rodents. European Journal of Pharmacology. 414: 225-31. PMID 11239923 DOI: 10.1016/S0014-2999(01)00771-3  0.348
2001 El Yacoubi M, Ledent C, Parmentier M, Daoust M, Costentin J, Vaugeois J. Absence of the adenosine A(2A) receptor or its chronic blockade decrease ethanol withdrawal-induced seizures in mice. Neuropharmacology. 40: 424-32. PMID 11166335 DOI: 10.1016/S0028-3908(00)00173-8  0.348
2000 Syringas M, Janin F, Mezghanni S, Giros B, Costentin J, Bonnet JJ. Structural domains of chimeric dopamine-noradrenaline human transporters involved in the Na(+)- and Cl(-)-dependence of dopamine transport. Molecular Pharmacology. 58: 1404-11. PMID 11093780 DOI: 10.1124/Mol.58.6.1404  0.482
2000 Corera AT, Costentin J, Bonnet JJ. Binding of uptake blockers to the neuronal dopamine transporter: further investigation about cationic and anionic requirements. Naunyn-Schmiedeberg's Archives of Pharmacology. 362: 213-21. PMID 10997723 DOI: 10.1007/S002100000280  0.305
2000 El Yacoubi M, Ledent C, Parmentier M, Costentin J, Vaugeois J. SCH 58261 and ZM 241385 differentially prevent the motor effects of CGS 21680 in mice: evidence for a functional 'atypical' adenosine A(2A) receptor. European Journal of Pharmacology. 401: 63-77. PMID 10915839 DOI: 10.1016/S0014-2999(00)00399-X  0.398
2000 El Yacoubi M, Ledent C, Ménard JF, Parmentier M, Costentin J, Vaugeois JM. The stimulant effects of caffeine on locomotor behaviour in mice are mediated through its blockade of adenosine A(2A) receptors. British Journal of Pharmacology. 129: 1465-73. PMID 10742303 DOI: 10.1038/Sj.Bjp.0703170  0.393
2000 Vilpoux C, Leroux-Nicollet I, Naudon L, Raisman-Vozari R, Costentin J. Reserpine or chronic paroxetine treatments do not modify the vesicular monoamine transporter 2 expression in serotonin-containing regions of the rat brain. Neuropharmacology. 39: 1075-82. PMID 10727718 DOI: 10.1016/S0028-3908(99)00210-5  0.361
2000 El Yacoubi M, Ledent C, Parmentier M, Costentin J, Vaugeois JM. The anxiogenic-like effect of caffeine in two experimental procedures measuring anxiety in the mouse is not shared by selective A(2A) adenosine receptor antagonists. Psychopharmacology. 148: 153-63. PMID 10663430 DOI: 10.1007/S002130050037  0.397
2000 El Yacoubi M, Ledent C, Parmentier M, Costentin J, Vaugeois J. The targeted disruption of the adenosine A2A receptor in mice reduces hypokinesia caused by haloperidol or reserpine and catalepsy induced by various drugs European Neuropsychopharmacology. 10: 366-367. DOI: 10.1016/S0924-977X(00)80489-7  0.366
1999 Garcia de Mateos-Verchere J, Leprince J, Tonon MC, Vaudry H, Costentin J. Reduction of pentylenetetrazol-induced convulsions by the octadecaneuropeptide ODN. Peptides. 20: 1431-6. PMID 10698118 DOI: 10.1016/S0196-9781(99)00153-9  0.423
1999 Florin S, Leblond F, Suaudeau C, Meunier JC, Costentin J. Comparison of behavioural effects of NocII or NocIII, two related pronociceptin-derived peptides. Life Sciences. 65: 2727-33. PMID 10622282 DOI: 10.1016/S0024-3205(99)00541-X  0.329
1999 Dubuc I, Remande S, Costentin J. The partial agonist properties of levocabastine in neurotensin-induced analgesia. European Journal of Pharmacology. 381: 9-12. PMID 10528128 DOI: 10.1016/S0014-2999(99)00554-3  0.398
1999 Régo JC, Syringas M, Leblond B, Costentin J, Bonnet JJ. Recovery of dopamine neuronal transporter but lack of change of its mRNA in substantia nigra after inactivation by a new irreversible inhibitor characterized in vitro and ex vivo in the rat. British Journal of Pharmacology. 128: 51-60. PMID 10498834 DOI: 10.1038/Sj.Bjp.0702784  0.44
1999 Vaugeois JM, Corera AT, Deslandes A, Costentin J. Although chemically related to amineptine, the antidepressant tianeptine is not a dopamine uptake inhibitor. Pharmacology, Biochemistry, and Behavior. 63: 285-90. PMID 10371658 DOI: 10.1016/S0091-3057(98)00242-1  0.501
1999 Cleren C, Vilpoux C, Dourmap N, Bonnet JJ, Costentin J. Acute interactions between L-DOPA and the neurotoxic effects of 1-methyl-4-phenylpyridinium or 6-hydroxydopamine in mice. Brain Research. 830: 314-9. PMID 10366688 DOI: 10.1016/S0006-8993(99)01420-1  0.419
1999 Do-Régo JC, Hue H, Costentin J, Bonnet JJ. Evidence for the sequential formation of two complexes between an uptake inhibitor, GBR 12783 [1-[2-(diphenylmethoxy)ethyl]-4-(3-phenyl-2-propenyl)piperazine], and the neuronal transporter of dopamine. Journal of Neurochemistry. 72: 396-404. PMID 9886093 DOI: 10.1046/J.1471-4159.1999.0720396.X  0.379
1999 Dubuc I, Sarret P, Labbé-Jullié C, Botto J, Honoré E, Bourdel E, Martinez J, Costentin J, Vincent J, Kitabgi P, Mazella J. Identification of the Receptor Subtype Involved in the Analgesic Effect of Neurotensin The Journal of Neuroscience. 19: 503-510. DOI: 10.1523/Jneurosci.19-01-00503.1999  0.388
1999 El Yacoubi M, Ledent C, Parmentier M, Costentin J, Vaugeois J. Selective adenosine A2A receptor antagonists are potential antidepressants: Evidence based on the activity of SCH 58261 and A2A knockout mice in screening procedures European Neuropsychopharmacology. 9: 249. DOI: 10.1016/S0924-977X(99)80232-6  0.349
1998 Garcia de Mateos-Verchere J, Vaugeois JM, Naudin B, Costentin J. Behavioural and neurochemical evidence that the antimicrobial agent oxolinic acid is a dopamine uptake inhibitor. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 8: 255-9. PMID 9928913 DOI: 10.1016/S0924-977X(97)00083-7  0.495
1998 Garcia de Mateos-Verchere J, Leprince J, Tonon MC, Vaudry H, Costentin J. The octadecaneuropeptide ODN inhibits apomorphine-induced yawning in rats. European Journal of Pharmacology. 357: 121-6. PMID 9797027 DOI: 10.1016/S0014-2999(98)00570-6  0.412
1998 Nail-Boucherie K, Dourmap N, Jaffard R, Costentin J. The specific dopamine uptake inhibitor GBR 12783 improves learning of inhibitory avoidance and increases hippocampal acetylcholine release. Brain Research. Cognitive Brain Research. 7: 203-5. PMID 9774732 DOI: 10.1016/S0926-6410(98)00023-8  0.41
1998 Le Pen G, Duterte-Boucher D, Daoust M, Costentin J. Pre-exposure to alcohol does not sensitize to the rewarding effects of cocaine. Neuroreport. 9: 2887-91. PMID 9760140 DOI: 10.1097/00001756-199808240-00038  0.779
1998 De Mateos-Verchere JG, Leprince J, Tonon MC, Vaudry H, Costentin J. The octadecaneuropeptide ODN induces anxiety in rodents: possible involvement of a shorter biologically active fragment. Peptides. 19: 841-8. PMID 9663449 DOI: 10.1016/S0196-9781(98)00037-0  0.417
1997 Vaugeois JM, Passera G, Zuccaro F, Costentin J. Individual differences in response to imipramine in the mouse tail suspension test. Psychopharmacology. 134: 387-91. PMID 9452181 DOI: 10.1007/S002130050475  0.335
1997 Ledent C, Vaugeois JM, Schiffmann SN, Pedrazzini T, El Yacoubi M, Vanderhaeghen JJ, Costentin J, Heath JK, Vassart G, Parmentier M. Aggressiveness, hypoalgesia and high blood pressure in mice lacking the adenosine A2a receptor. Nature. 388: 674-8. PMID 9262401 DOI: 10.1038/41771  0.356
1997 Florin S, Leroux-Nicollet I, Meunier JC, Costentin J. Autoradiographic localization of [3H]nociceptin binding sites from telencephalic to mesencephalic regions of the mouse brain. Neuroscience Letters. 230: 33-6. PMID 9259457 DOI: 10.1016/S0304-3940(97)00470-9  0.319
1997 Drouet I, Suaudeau C, Dourmap N, Costentin J. Mechanism of the hypothermic effect of MPP+ administered centrally in mice. Neuropharmacology. 36: 993-7. PMID 9257943 DOI: 10.1016/S0028-3908(97)00077-4  0.441
1997 Dourmap N, Clero E, Costentin J. Involvement of cholinergic neurons in the release of dopamine elicited by stimulation of mu-opioid receptors in striatum. Brain Research. 749: 295-300. PMID 9138730 DOI: 10.1016/S0006-8993(96)01319-4  0.41
1997 Florin S, Suaudeau C, Meunier JC, Costentin J. Orphan neuropeptide NocII, a putative pronociceptin maturation product, stimulates locomotion in mice. Neuroreport. 8: 705-7. PMID 9106751 DOI: 10.1097/00001756-199702100-00025  0.44
1996 Le Pen G, Duterte-Boucher D, Costentin J. Place conditioning with cocaine and the dopamine uptake inhibitor GBR12783. Neuroreport. 7: 2839-42. PMID 9116192 DOI: 10.1097/00001756-199611250-00005  0.807
1996 Naudon L, Raisman-Vozari R, Edwards RH, Leroux-Nicollet I, Peter D, Liu Y, Costentin J. Reserpine affects differentially the density of the vesicular monoamine transporter and dihydrotetrabenazine binding sites. The European Journal of Neuroscience. 8: 842-6. PMID 9081637 DOI: 10.1111/J.1460-9568.1996.Tb01271.X  0.325
1996 Florin S, Suaudeau C, Meunier JC, Costentin J. Nociceptin stimulates locomotion and exploratory behaviour in mice. European Journal of Pharmacology. 317: 9-13. PMID 8982713 DOI: 10.1016/S0014-2999(96)00707-8  0.47
1996 Simon P, Hémet C, Costentin J. Analysis of stimulant locomotor effects of modafinil in various strains of mice and rats. Fundamental & Clinical Pharmacology. 10: 431-5. PMID 8902545 DOI: 10.1111/J.1472-8206.1996.Tb00597.X  0.392
1996 Thibaut F, Bonnet JJ, Vaugeois JM, Costentin J. Pharmacological modifications of dopamine transmission do not influence the striatal in vivo binding of [3H]mazindol or [3H]cocaine in mice. Neuroscience Letters. 205: 145-8. PMID 8852579 DOI: 10.1016/0304-3940(96)12399-5  0.443
1996 Thibaut F, Vaugeois JM, Bonnet JJ, Costentin J. In vivo striatal binding of the D1 antagonist SCH 23390 is not modified by changes in dopaminergic transmission. Neuropharmacology. 35: 267-72. PMID 8783200 DOI: 10.1016/0028-3908(95)00187-5  0.457
1996 Héron C, Billaud G, Costentin J, Bonnet JJ. Complex ionic control of [3H]GBR 12783 binding to the dopamine neuronal carrier. European Journal of Pharmacology. 301: 195-202. PMID 8773464 DOI: 10.1016/0014-2999(96)00050-7  0.301
1996 Corera AT, Costentin J, Bonnet JJ. Effect of low concentrations of K+ and Cl- on the Na(+)-dependent neuronal uptake of [3H] dopamine. Naunyn-Schmiedeberg's Archives of Pharmacology. 353: 610-5. PMID 8738293 DOI: 10.1007/Bf00167179  0.316
1996 Boulay D, Duterte-Boucher D, Nouel D, Costentin J. Locomotor sensitization to [D-Trp(11)]neurotensin after repeated injections of the dopamine uptake inhibitor GBR12783 in rats. Neuroscience Letters. 208: 5-8. PMID 8731161 DOI: 10.1016/0304-3940(96)12531-3  0.806
1996 Vaugeois JM, Pouhé D, Zuccaro F, Costentin J. Indirect dopamine agonists effects on despair test: dissociation from hyperactivity. Pharmacology, Biochemistry, and Behavior. 54: 235-9. PMID 8728563 DOI: 10.1016/0091-3057(95)02131-0  0.471
1996 Griffon N, Sautel F, Pilon C, Lévesque D, Sokoloff P, Schwartz JC, Diaz J, Simon P, Costentin J, Mann A, Wermuth CG. Functional models for the dopamine D3 receptor. Biochemical Society Transactions. 24: 193-8. PMID 8674660 DOI: 10.1042/bst0240193  0.467
1995 Simon P, Hémet C, Ramassamy C, Costentin J. Non-amphetaminic mechanism of stimulant locomotor effect of modafinil in mice. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 5: 509-14. PMID 8998404 DOI: 10.1016/0924-977X(95)80011-P  0.491
1995 Naudin B, Bonnet JJ, Costentin J. Acute L-DOPA pretreatment potentiates 6-hydroxydopamine-induced toxic effects on nigro-striatal dopamine neurons in mice. Brain Research. 701: 151-7. PMID 8925278 DOI: 10.1016/0006-8993(95)00988-7  0.445
1995 Griffon N, Sokoloff P, Diaz J, Lévesque D, Sautel F, Schwartz JC, Simon P, Costentin J, Garrido F, Mann A. The dopamine D3 receptor and schizophrenia: pharmacological, anatomical and genetic approaches. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 5: 3-9. PMID 8775753 DOI: 10.1016/0924-977X(95)00030-S  0.509
1995 Naudon L, Leroux-Nicollet I, Raisman-Vozari R, Botton D, Costentin J. Time-course of modifications elicited by reserpine on the density and mRNA synthesis of the vesicular monoamine transporter, and on the density of the membrane dopamine uptake complex. Synapse (New York, N.Y.). 21: 29-36. PMID 8525459 DOI: 10.1002/Syn.890210105  0.418
1995 Refahi-Lyamani F, Saadouni S, Costentin J, Bonnet JJ. Interaction of two sulfhydryl reagents with a cation recognition site on the neuronal dopamine carrier evidences small differences between [3H]GBR 12783 and [3H]cocaine binding sites. Naunyn-Schmiedeberg's Archives of Pharmacology. 351: 136-45. PMID 7770096 DOI: 10.1007/Bf00169327  0.344
1995 Suaudeau C, Costentin J. Analgesic effect of the direct D2 dopamine receptor agonist RU 24926 and cross tolerance with morphine. Fundamental & Clinical Pharmacology. 9: 147-52. PMID 7628827 DOI: 10.1111/J.1472-8206.1995.Tb00274.X  0.451
1995 Suaudeau C, Dourmap N, Costentin J. Rapid and long lasting reduction of the hypothermic effect of a D2 dopamine agonist after an intracerebroventricular injection of 6-hydroxydopamine. Neuropharmacology. 34: 101-5. PMID 7623958 DOI: 10.1016/0028-3908(94)00109-6  0.475
1995 Ramassamy C, Girbe F, Christen Y, Costentin J. Peroxidation of synaptosomes alters the dopamine uptake complex but spares the exocytotic release of dopamine. Neurodegeneration : a Journal For Neurodegenerative Disorders, Neuroprotection, and Neuroregeneration. 4: 155-60. PMID 7583679 DOI: 10.1006/Neur.1995.0019  0.378
1995 Meunier JC, Mollereau C, Toll L, Suaudeau C, Moisand C, Aivinerie P, Butour JL, Guillemot JC, Ferrara P, Monsarrat B, Mazarguil H, Vassart G, Parmentler M, Costentin J. Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor Nature. 377: 532-X. PMID 7566152 DOI: 10.1038/377532A0  0.344
1995 Schwartz JC, Griffon N, Diaz J, Levesque D, Sautel F, Sokoloff P, Simon P, Costentin J, Garrido F, Mann A, Wermuth C. The D3 receptor and its relevance in psychiatry International Clinical Psychopharmacology. 10: 15-20. DOI: 10.1097/00004850-199509000-00003  0.397
1995 Griffon N, Diaz J, Levesque D, Sautel F, Schwartz J, Sokoloff P, Simon P, Costentin J, Garrido F, Mann A, Wermuth C. Localization, Regulation, and Role of the Dopamine D3 Receptor Are Distinct from Those of the D2 Receptor Clinical Neuropharmacology. 18: S130-S142. DOI: 10.1097/00002826-199501001-00015  0.363
1994 Dourmap N, Costentin J. Involvement of glutamate receptors in the striatal enkephalin-induced dopamine release. European Journal of Pharmacology. 253: R9-11. PMID 8200414 DOI: 10.1016/0014-2999(94)90210-0  0.409
1994 Bonnet JJ, Benmansour S, Amejdki-Chab N, Costentin J. Effect of CH3HgCl and several transition metals on the dopamine neuronal carrier; peculiar behaviour of Zn2+. European Journal of Pharmacology. 266: 87-97. PMID 8137886 DOI: 10.1016/0922-4106(94)90213-5  0.324
1994 Girbe F, Ramassamy C, Piton C, Costentin J. Ascorbic acid increases synaptosomal potassium-induced dopamine release. Neuroreport. 5: 1027-9. PMID 8080951 DOI: 10.1097/00001756-199405000-00002  0.353
1994 Dubuc I, Costentin J, Terranova JP, Barnouin MC, Soubrié P, Le Fur G, Rostène W, Kitabgi P. The nonpeptide neurotensin antagonist, SR 48692, used as a tool to reveal putative neurotensin receptor subtypes. British Journal of Pharmacology. 112: 352-4. PMID 8075852 DOI: 10.1111/J.1476-5381.1994.Tb13077.X  0.382
1994 Nouel D, Costentin J. Locomotor effects of [D-Trp11]neurotensin and dopamine transmission in rats. European Journal of Pharmacology. 254: 263-9. PMID 8013561 DOI: 10.1016/0014-2999(94)90463-4  0.378
1994 Saadouni S, Refahi-Lyamani F, Costentin J, Bonnet JJ. Cocaine and GBR 12783 recognize nonidentical, overlapping binding domains on the dopamine neuronal carrier. European Journal of Pharmacology. 268: 187-97. PMID 7957640 DOI: 10.1016/0922-4106(94)90188-0  0.362
1994 Simon P, Dupuis R, Costentin J. Thigmotaxis as an index of anxiety in mice. Influence of dopaminergic transmissions. Behavioural Brain Research. 61: 59-64. PMID 7913324 DOI: 10.1016/0166-4328(94)90008-6  0.459
1994 Simon P, Panissaud C, Costentin J. The stimulant effect of modafinil on wakefulness is not associated with an increase in anxiety in mice. A comparison with dexamphetamine. Psychopharmacology. 114: 597-600. PMID 7855221 DOI: 10.1007/Bf02244990  0.389
1994 Billaud G, Menard JF, Marcellin N, Kamenka JM, Costentin J, Bonnet JJ. Thermodynamics of the binding of BTCP (GK 13) and related derivatives on the dopamine neuronal carrier. European Journal of Pharmacology. 268: 357-63. PMID 7805759 DOI: 10.1016/0922-4106(94)90060-4  0.349
1994 Boulay D, Leroux-Nicollet I, Duterte-Boucher D, Naudon L, Costentin J. Invariance of the density of dopamine uptake sites and dopamine metabolism in the rat brain after a chronic treatment with the dopamine uptake inhibitor GBR 12783. Journal of Neural Transmission. General Section. 98: 209-15. PMID 7748521 DOI: 10.1007/Bf01276537  0.805
1994 Héron C, Costentin J, Bonnet JJ. Evidence that pure uptake inhibitors including cocaine interact slowly with the dopamine neuronal carrier. European Journal of Pharmacology. 264: 391-8. PMID 7698180 DOI: 10.1016/0014-2999(94)00502-8  0.409
1994 Naudon L, Leroux-Nicollet I, Costentin J. Short-term treatments with haloperidol or bromocriptine do not alter the density of the monoamine vesicular transporter in the substantia nigra. Neuroscience Letters. 173: 1-4. PMID 7523993 DOI: 10.1016/0304-3940(94)90136-8  0.444
1994 Vaugeois J, Pouhé D, Lemonnier F, Costentin J. Neurochemical and behavioral evidence for a central indirect dopaminergic agonist activity of the antidepressant medifoxamine in mice European Neuropsychopharmacology. 4: 323-324. DOI: 10.1016/0924-977X(94)90140-6  0.376
1993 Vaugeois JM, Bonnet JJ, Duterte-Boucher D, Costentin J. In vivo occupancy of the striatal dopamine uptake complex by various inhibitors does not predict their effects on locomotion. European Journal of Pharmacology. 230: 195-201. PMID 8422901 DOI: 10.1016/0014-2999(93)90802-O  0.784
1993 Billaud G, Costentin J, Bonnet JJ. Specific binding of [3H]GBR 12783 to the dopamine neuronal carrier included in polarized membranes. European Journal of Pharmacology. 247: 333-40. PMID 8307105 DOI: 10.1016/0922-4106(93)90203-L  0.35
1993 Simon P, Bertrand J, Costentin J. 5-HT1A receptor blockade increases penile erections induced by indirect serotonin agonists. Neuroreport. 5: 229-30. PMID 7905292 DOI: 10.1097/00001756-199312000-00010  0.374
1993 Ilagouma A, Maurice T, Duterte-Boucher D, Coderc E, Vignon J, Costentin J, Kamenka J. Arylcyclohexylamines derived from BTCP are potent indirect catecholamine agonists European Journal of Medicinal Chemistry. 28: 377-385. DOI: 10.1016/0223-5234(93)90124-W  0.765
1992 Amejdki-Chab N, Costentin J, Bonnet JJ. Kinetic analysis of the chloride dependence of the neuronal uptake of dopamine and effect of anions on the ability of substrates to compete with the binding of the dopamine uptake inhibitor GBR 12783. Journal of Neurochemistry. 58: 793-800. PMID 1737991 DOI: 10.1111/J.1471-4159.1992.Tb09327.X  0.386
1992 Dourmap N, Michael-Titus A, Costentin J. Differential effect of intrastriatal kainic acid on the modulation of dopamine release by mu- and delta-opioid peptides: a microdialysis study. Journal of Neurochemistry. 58: 709-13. PMID 1729411 DOI: 10.1111/J.1471-4159.1992.Tb09775.X  0.402
1992 Naudon L, Dourmap N, Leroux-Nicollet I, Costentin J. Kainic acid lesion of the striatum increases dopamine release but reduces 3-methoxytyramine level. Brain Research. 572: 247-9. PMID 1611519 DOI: 10.1016/0006-8993(92)90477-Q  0.344
1992 Duterte-Boucher D, Duhamel F, Costentin J. Dopaminergic transmission and (+)amphetamine-induced lethality in aggregated mice. Fundamental & Clinical Pharmacology. 6: 21-7. PMID 1555808 DOI: 10.1111/J.1472-8206.1992.Tb00090.X  0.785
1992 Suaudeau C, Bousselmame R, Costentin J. A different balance in the sensitivity of D1 and D2 dopamine receptors accounts for differences in apomorphine-induced hypothermic effects in Swiss and C3H mice. Neuropharmacology. 31: 1115-9. PMID 1475020 DOI: 10.1016/0028-3908(92)90007-C  0.406
1992 Ramassamy C, Naudin B, Christen Y, Clostre F, Costentin J. Prevention by Ginkgo biloba extract (EGb 761) and trolox C of the decrease in synaptosomal dopamine or serotonin uptake following incubation. Biochemical Pharmacology. 44: 2395-401. PMID 1472105 DOI: 10.1016/0006-2952(92)90685-C  0.332
1992 Simon P, Panissaud C, Costentin J. Sulpiride anxiogenic-like effect inhibition by a D1 dopamine receptor antagonist. Neuroreport. 3: 941-2. PMID 1421103 DOI: 10.1097/00001756-199210000-00031  0.468
1992 Amejdki-Chab N, Benmansour S, Costentin J, Bonnet JJ. Effects of several cations on the neuronal uptake of dopamine and the specific binding of [3H]GBR 12783: attempts to characterize the Na+ dependence of the neuronal transport of dopamine. Journal of Neurochemistry. 59: 1795-804. PMID 1402923 DOI: 10.1111/J.1471-4159.1992.Tb11012.X  0.342
1992 Ramassamy C, Christen Y, Clostre F, Costentin J. The Ginkgo biloba extract, EGb761, increases synaptosomal uptake of 5-hydroxytryptamine: in-vitro and ex-vivo studies. The Journal of Pharmacy and Pharmacology. 44: 943-5. PMID 1361545 DOI: 10.1111/J.2042-7158.1992.Tb03244.X  0.319
1992 Naudon L, Leroux-Nicollet I, Costentin J. Consequences of an intrastriatal injection of kainic acid on the dopaminergic neuronal and vesicular uptake systems. Brain Research. 593: 32-8. PMID 1360863 DOI: 10.1016/0006-8993(92)91259-H  0.386
1992 Simon P, Guardiola B, Bizot-Espiard J, Schiavi P, Costentin J. 5-HT1A receptor agonists prevent in rats the yawning and penile erections induced by direct dopamine agonists. Psychopharmacology. 108: 47-50. PMID 1357709 DOI: 10.1007/BF02245284  0.391
1992 Vaugeois JM, Bonnet JJ, Costentin J. In vivo labelling of the neuronal dopamine uptake complex in the mouse striatum by [3H]GBR 12783. European Journal of Pharmacology. 210: 77-84. PMID 1350989 DOI: 10.1016/0014-2999(92)90654-M  0.42
1992 Nouel D, Costentin J, Lugrin D, Kitabgi P, Ple N, Davoust D. Investigations about a direct neurotensin-dopamine interaction by nuclear magnetic resonance study, synaptosomal uptake of dopamine, and binding of neurotensin to its receptors. Journal of Neurochemistry. 59: 1933-6. PMID 1328532 DOI: 10.1111/J.1471-4159.1992.Tb11029.X  0.395
1991 Bousselmame R, Eustache M, Michael-Titus A, Costentin J. Chronic inhibition of enkephalinase induces changes in the antinociceptive and locomotor effects of the enkephalinase inhibitor acetorphan in rats. Neuropharmacology. 30: 865-70. PMID 1780043 DOI: 10.1016/0028-3908(91)90120-Z  0.387
1991 Naudin B, Saligaut C, Costentin J. Influence of oxygen availability on the neurotoxic effect of 6-hydroxydopamine on nigro-striatal dopaminergic neurons. Neuroscience Letters. 130: 22-6. PMID 1749514 DOI: 10.1016/0304-3940(91)90218-I  0.408
1991 Ladurelle N, Duterte-Boucher D, Costentin J. Stimulation of D1 and D2 dopamine receptors produces additive anorectic effects. Fundamental & Clinical Pharmacology. 5: 481-90. PMID 1683341 DOI: 10.1111/J.1472-8206.1991.Tb00734.X  0.771
1991 Bousselmame R, Michael-Titus A, Costentin J. Desensitization of mu-opioid receptors does not modify the analgesia induced by an enkephalinase inhibitor. European Journal of Pharmacology. 203: 295-7. PMID 1666049 DOI: 10.1016/0014-2999(91)90728-9  0.389
1990 Dourmap N, Michael-Titus A, Costentin J. Acetorphan, an Enkephalinase Inhibitor, Modulates Dopaminergic Transmission in Rat Olfactory Tubercle, but not in the Nucleus Accumbens and Striatum. The European Journal of Neuroscience. 2: 783-787. PMID 12106279 DOI: 10.1111/J.1460-9568.1990.Tb00469.X  0.448
1990 Nouel D, Dubuc I, Kitabgi P, Costentin J. Centrally administered [D-Trp11]neurotensin, as well as neurotensin protected from inactivation by thiorphan, modifies locomotion in rats in a biphasic manner. Peptides. 11: 551-5. PMID 2381875 DOI: 10.1016/0196-9781(90)90058-D  0.419
1990 Vaugeois JM, Bonnet JJ, Costentin J. Relationship between the effects of dexamphetamine on locomotion and on striatal [3H]GBR 12783 binding in vivo. European Journal of Pharmacology. 178: 221-7. PMID 2328762 DOI: 10.1016/0014-2999(90)90478-O  0.458
1990 Leroux-Nicollet I, Darchen F, Scherman D, Costentin J. Postnatal development of the monoamine vesicular transporter in mesencephalic and telencephalic regions of the rat brain: a quantitative autoradiographic study with [3H]dihydrotetrabenazine. Neuroscience Letters. 117: 1-7. PMID 2290604 DOI: 10.1016/0304-3940(90)90110-U  0.334
1990 Michael-Titus A, Bousselmame R, Costentin J. Stimulation of dopamine D2 receptors induces an analgesia involving an opioidergic but non enkephalinergic link. European Journal of Pharmacology. 187: 201-7. PMID 2176983 DOI: 10.1016/0014-2999(90)90007-S  0.368
1990 Ramassamy C, Clostre F, Christen Y, Costentin J. Prevention by a Ginkgo biloba extract (GBE 761) of the dopaminergic neurotoxicity of MPTP. The Journal of Pharmacy and Pharmacology. 42: 785-9. PMID 1982302 DOI: 10.1111/J.2042-7158.1990.Tb07021.X  0.458
1990 Michael-Titus A, Dourmap N, Costentin J, Schwartz JC. Role of delta opioid receptors in the effects of inhibitors of enkephalin-degrading peptidases on the horizontal and vertical components of locomotion in mice. Neuropeptides. 15: 89-100. PMID 1981928 DOI: 10.1016/0143-4179(90)90044-Y  0.544
1990 Rognan D, Sokoloff P, Mann A, Martres MP, Schwartz JC, Costentin J, Wermuth CG. Optically active benzamides as predictive tools for mapping the dopamine D2 receptor. European Journal of Pharmacology. 189: 59-70. PMID 1977603 DOI: 10.1016/0922-4106(90)90230-U  0.525
1990 Naudin B, Canu S, Costentin J. Effects of various direct or indirect dopamine agonists on the latency of the acoustic startle response in rats. Journal of Neural Transmission. General Section. 82: 43-53. PMID 1976319 DOI: 10.1007/BF01244833  0.373
1990 Dourmap N, Michael-Titus A, Costentin J. Local enkephalins tonically modulate dopamine release in the striatum: a microdialysis study. Brain Research. 524: 153-5. PMID 1976029 DOI: 10.1016/0006-8993(90)90505-6  0.379
1990 Duterte-Boucher D, Kamenka JM, Costentin J. Comparison of the effects of three indirect dopamine agonists, GK 13, GBR 12783 and dexamphetamine on behavioural tests involving central catecholaminergic transmissions. Psychopharmacology. 101: 344-53. PMID 1972995 DOI: 10.1007/Bf02244052  0.768
1990 Costentin J, Duterte-Boucher D, Panissaud C, Michael-Titus A. Dopamine D1 and D2 receptors mediate opposite effects of apomorphine on the body temperature of reserpinized mice. Neuropharmacology. 29: 31-5. PMID 1968237 DOI: 10.1016/0028-3908(90)90080-B  0.778
1989 Bonnet JJ, Costentin J. Correlation between (3H)dopamine specific uptake and (3H)GBR 12783 specific binding during the maturation of rat striatum. Life Sciences. 44: 1759-65. PMID 2733550 DOI: 10.1016/0024-3205(89)90563-8  0.382
1989 Thibaut F, Bonnet JJ, Costentin J. Time course of postmortem modifications in synaptosomal [3H]dopamine uptake and [3H]GBR 12783 binding to the dopamine uptake complex in the rat striatum. Neuroscience Letters. 96: 335-9. PMID 2717059 DOI: 10.1016/0304-3940(89)90401-1  0.383
1989 Duterte-Boucher D, Panissaud C, Michael-Titus A, Costentin J. Stimulation of central D1 dopamine receptors reverses reserpine-induced hypothermia in mice. Neuropharmacology. 28: 419-21. PMID 2568597 DOI: 10.1016/0028-3908(89)90039-7  0.786
1989 Duterte-Boucher D, Naudin B, Costentin J. Characteristics of the dopamine receptors involved in the anorectic effects of apomorphine in mice. Fundamental & Clinical Pharmacology. 3: 337-46. PMID 2553567 DOI: 10.1111/J.1472-8206.1989.Tb00675.X  0.78
1989 Michael-Titus A, Dourmap N, Costentin J. MU and delta opioid receptors control differently the horizontal and vertical components of locomotor activity in mice. Neuropeptides. 13: 235-42. PMID 2546089 DOI: 10.1016/0143-4179(89)90076-0  0.386
1989 Duterte-Boucher D, Costentin J. Appearance of a stereotyped apomorphine-induced climbing in unresponsive DBA2 mice after subchronic manipulations of brain dopamine transmission. Psychopharmacology. 98: 56-60. PMID 2543019 DOI: 10.1007/Bf00442006  0.788
1988 Coquerel A, Dubuc I, Kitaegi P, Costentin J. Potentiation by thiorphan and bestatin of the naloxone-insensitive analgesic effects of neurotensin and neuromedin n. Neurochemistry International. 12: 361-6. PMID 20501239 DOI: 10.1016/0197-0186(88)90175-1  0.397
1988 Dubuc I, Nouel D, Coquerel A, Menard JF, Kitabgi P, Costentin J. Hypothermic effect of neuromedin N in mice and its potentiation by peptidase inhibitors. European Journal of Pharmacology. 151: 117-21. PMID 3416919 DOI: 10.1016/0014-2999(88)90699-1  0.316
1988 Bonnet JJ, Benmansour S, Vaugeois JM, Costentin J. Ionic requirements for the specific binding of [3H]GBR 12783 to a site associated with the dopamine uptake carrier. Journal of Neurochemistry. 50: 759-65. PMID 3339350 DOI: 10.1111/J.1471-4159.1988.Tb02979.X  0.305
1988 Leroux-Nicollet I, Costentin J. In vivo and in vitro autoradiographic labelling of central dopaminergic systems with [3H]GBR12783 in rodents. Neuroscience Letters. 95: 7-12. PMID 2976132 DOI: 10.1016/0304-3940(88)90623-4  0.38
1988 Leroux-Nicollet I, Panissaud C, Costentin J. Involvement of norepinephrine neurons in the hypothermia induced by intracerebroventricular administration of 6-hydroxydopamine in mice, evidenced by antidepressants. Journal of Neural Transmission. 74: 17-27. PMID 2971783 DOI: 10.1007/Bf01243572  0.462
1988 Duterte-Boucher D, Leclère JF, Panissaud C, Costentin J. Acute effects of direct dopamine agonists in the mouse behavioral despair test. European Journal of Pharmacology. 154: 185-90. PMID 2906611 DOI: 10.1016/0014-2999(88)90096-9  0.793
1987 Chagraoui A, Bonnet JJ, Protais P, Costentin J. In vivo binding of [3H]GBR 12783, a selective dopamine uptake inhibitor, in mouse striatum. Neuroscience Letters. 78: 175-9. PMID 3627558 DOI: 10.1016/0304-3940(87)90629-X  0.453
1987 Bonnet JJ, Chagraoui A, Protais P, Costentin J. Interactions of amineptine with the neuronal dopamine uptake system: neurochemical in vitro and in vivo studies. Journal of Neural Transmission. 69: 211-20. PMID 3625193 DOI: 10.1007/BF01244342  0.331
1987 Benmansour S, Bonnet JJ, Protais P, Costentin J. Sodium independence of the binding of [3H]GBR 12783 and other dopamine uptake inhibitors to the dopamine uptake complex. Neuroscience Letters. 77: 97-102. PMID 3601221 DOI: 10.1016/0304-3940(87)90614-8  0.347
1987 Marçais-Collado H, Uchida G, Costentin J, Schwartz JC, Lecomte JM. Naloxone-reversible antidiarrheal effects of enkephalinase inhibitors. European Journal of Pharmacology. 144: 125-32. PMID 3481337 DOI: 10.1016/0014-2999(87)90510-3  0.513
1987 Michael-Titus A, Costentin J. Analgesic effects of metapramine and evidence against the involvement of endogenous enkephalins in the analgesia induced by tricyclic antidepressants. Pain. 31: 391-400. PMID 2827090 DOI: 10.1016/0304-3959(87)90167-9  0.325
1986 Bonnet JJ, Costentin J. GBR 12783, a potent and selective inhibitor of dopamine uptake: biochemical studies in vivo and ex vivo. European Journal of Pharmacology. 121: 199-209. PMID 3754516 DOI: 10.1016/0014-2999(86)90491-7  0.428
1986 Costentin J, Vlaiculescu A, Chaillet P, Ben Natan L, Aveaux D, Schwartz JC. Dissociated effects of inhibitors of enkephalin-metabolising peptidases or naloxone on various nociceptive responses. European Journal of Pharmacology. 123: 37-44. PMID 3519246 DOI: 10.1016/0014-2999(86)90684-9  0.51
1986 Bonnet JJ, Protais P, Chagraoui A, Costentin J. High-affinity [3H]GBR 12783 binding to a specific site associated with the neuronal dopamine uptake complex in the central nervous system. European Journal of Pharmacology. 126: 211-22. PMID 3489625 DOI: 10.1016/0014-2999(86)90050-6  0.413
1985 Vasse M, Protais P, Costentin J, Schwartz JC. Unexpected potentiation by discriminant benzamide derivatives of stereotyped behaviours elicited by dopamine agonists in mice. Naunyn-Schmiedeberg's Archives of Pharmacology. 329: 108-16. PMID 4040215 DOI: 10.1007/Bf00501198  0.596
1985 Waksman G, Bouboutou R, Chaillet P, Devin J, Coulaud A, Hamel E, Besselievre R, Costentin J, Fournie-Zaluski MC, Roques BP. Kelatorphan: a full inhibitor of enkephalin degrading enzymes. Biochemical and pharmacological properties, regional distribution of enkephalinase in rat brain by use of a tritiated derivative. Neuropeptides. 5: 529-32. PMID 3839056 DOI: 10.1016/0143-4179(85)90071-X  0.316
1985 Protais P, Hermier C, Costentin J. The discriminant dopamine antagonist property of benzamides is observed at various times after their systemic or intracerebroventricular administration. Neuropharmacology. 24: 861-7. PMID 2865694 DOI: 10.1016/0028-3908(85)90037-1  0.345
1985 Schwartz J, Costentin J, Lecomte J. Pharmacology of enkephalinase inhibitors Trends in Pharmacological Sciences. 6: 472-476. DOI: 10.1016/0165-6147(85)90226-3  0.459
1984 Lemasson MH, Bonnet JJ, Costentin J. Artefactual inhibition of dopamine uptake by psychotropic drugs on striatal synaptosomal preparation. Biochemical Pharmacology. 33: 2137-41. PMID 6743358 DOI: 10.1016/0006-2952(84)90584-7  0.392
1984 Bonnet JJ, Lemasson MH, Costentin J. Simultaneous evaluation by a double labelling method of drug-induced uptake inhibition and release of dopamine in synaptosomal preparation of rat striatum. Biochemical Pharmacology. 33: 2129-35. PMID 6743357 DOI: 10.1016/0006-2952(84)90583-5  0.387
1984 Natan LB, Chaillet P, Lecomte JM, Marçais H, Uchida G, Costentin J. Involvement of endogenous enkephalins in the mouse 'behavioral despair' test. European Journal of Pharmacology. 97: 301-4. PMID 6584312 DOI: 10.1016/0014-2999(84)90464-3  0.328
1984 Protais P, Bonnet JJ, Costentin J, Schwartz JC. Rat climbing behavior elicited by stimulation of cerebral dopamine receptors. Naunyn-Schmiedeberg's Archives of Pharmacology. 325: 93-101. PMID 6425703 DOI: 10.1007/Bf00506188  0.574
1984 Fournie-Zaluski MC, Chaillet P, Bouboutou R, Coulaud A, Cherot P, Waksman G, Costentin J, Roques BP. Analgesic effects of kelatorphan, a new highly potent inhibitor of multiple enkephalin degrading enzymes. European Journal of Pharmacology. 102: 525-8. PMID 6386492 DOI: 10.1016/0014-2999(84)90575-2  0.33
1984 Martres MP, Sokoloff P, Delandre M, Schwartz JC, Protais P, Costentin J. Selection of dopamine antagonists discriminating various behavioral responses and radioligand binding sites. Naunyn-Schmiedeberg's Archives of Pharmacology. 325: 102-15. PMID 6144046 DOI: 10.1007/Bf00506189  0.541
1984 Chaillet P, Coulaud A, Zajac JM, Fournie-Zaluski MC, Costentin J, Roques BP. The mu rather than the delta subtype of opioid receptors appears to be involved in enkephalin-induced analgesia. European Journal of Pharmacology. 101: 83-90. PMID 6086366 DOI: 10.1016/0014-2999(84)90033-5  0.36
1983 Chaillet P, Marçais-Collado H, Costentin J. Catatonic or hypotonic immobility induced in mice by intracerebroventricular injection of mu or kappa opioid receptor agonists as well as enkephalins or inhibitors of their degradation. Life Sciences. 33: 2105-11. PMID 6685806 DOI: 10.1016/0024-3205(83)90334-X  0.418
1983 Colboc O, Protais P, Costentin J. Pharmacological evidence against the involvement of the D1 subtype of dopamine receptors in apomorphine-induced hypothermia. Neuroscience Letters. 39: 211-6. PMID 6633953 DOI: 10.1016/0304-3940(83)90079-4  0.454
1983 Chaillet P, Marçais-Collado H, Costentin J, Yi CC, De La Baume S, Schwartz JC. Inhibition of enkephalin metabolism by, and antinociceptive activity of, bestatin, an aminopeptidase inhibitor. European Journal of Pharmacology. 86: 329-36. PMID 6572590 DOI: 10.1016/0014-2999(83)90181-4  0.517
1983 Chaillet P, Coulaud A, Fournié-Zaluski MC, Gacel G, Roques BP, Costentin J. Pain control by endogenous enkephalins is mediated by mu opioid receptors. Life Sciences. 33: 685-8. PMID 6319920 DOI: 10.1016/0024-3205(83)90595-7  0.355
1983 de la Baume S, Yi CC, Schwartz JC, Chaillet P, Marcais-Collado H, Costentin J. Participation of both 'enkephalinase' and aminopeptidase activities in the metabolism of endogenous enkephalins. Neuroscience. 8: 143-51. PMID 6300726 DOI: 10.1016/0306-4522(83)90033-7  0.321
1983 Fournié-Zaluski MC, Chaillet P, Soroca-Lucas E, Marçais-Collado H, Costentin J, Roques BP. New carboxyalkyl inhibitors of brain enkephalinase: synthesis, biological activity, and analgesic properties. Journal of Medicinal Chemistry. 26: 60-5. PMID 6298420 DOI: 10.1002/Chin.198326167  0.36
1983 Protais P, Dubuc I, Costentin J. Pharmacological characteristics of dopamine receptors involved in the dual effect of dopamine agonists on yawning behaviour in rats. European Journal of Pharmacology. 94: 271-80. PMID 6140175 DOI: 10.1016/0014-2999(83)90416-8  0.437
1983 Protais P, Bonnet JJ, Costentin J. Pharmacological characterization of the receptors involved in the apomorphine-induced polyphasic modifications of locomotor activity in mice. Psychopharmacology. 81: 126-34. PMID 6138794 DOI: 10.1007/Bf00429006  0.445
1982 de la Baume S, Gros C, Yi CC, Chaillet P, Marcais-Collado H, Costentin J, Schwartz JC. Selective participation of both "enkephalinase" and aminopeptidase activities in the metabolism of endogenous enkephalins. Life Sciences. 31: 1753-6. PMID 6759827 DOI: 10.1016/0024-3205(82)90202-8  0.483
1982 Schwartz JC, De La Baume S, Yi CC, Chaillet P, Marcais-Collado H, Costentin J. Enkephalin metabolism in brain and its inhibition. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 6: 665-71. PMID 6298893 DOI: 10.1016/S0278-5846(82)80166-8  0.389
1982 Dubuc I, Protais P, Colboc O, Costentin J. Antagonism of the apomorphine-induced yawning by "atypical" neuroleptics. Neuropharmacology. 21: 1203-6. PMID 6129594 DOI: 10.1016/0028-3908(82)90181-2  0.397
1982 Colboc O, Protais P, Costentin J. Histamine-induced rise in core temperature of chloral-anaesthetized rats: mediation by H2-receptors located in the preopticus area of hypothalamus. Neuropharmacology. 21: 45-50. PMID 6121300 DOI: 10.1016/0028-3908(82)90209-X  0.374
1981 Marçais H, Bonnet JJ, Costentin J. Evidence for sedative effects of low doses of morphine in mice involving receptors insensitive to naloxone. Life Sciences. 28: 2737-42. PMID 6267395 DOI: 10.1016/0024-3205(81)90174-0  0.397
1981 Barghon R, Protais P, Colboc O, Costentin J. Hypokinesia in mice and catalepsy in rats elicited by morphine associated with antidopaminergic agents, including atypical neuroleptics. Neuroscience Letters. 27: 69-73. PMID 6120489 DOI: 10.1016/0304-3940(81)90207-X  0.404
1979 de la Baume S, Patey G, Marçais H, Protais P, Costentin J, Schwartz JC. Changes in dopamine receptors in mouse striatum following morphine treatments. Life Sciences. 24: 2333-42. PMID 573360 DOI: 10.1016/0024-3205(79)90531-9  0.573
1979 Marcais H, Protais P, Costentin J. Hypersensitivity of the climbing behaviour response to apomorphine induced by a short depression of dopaminergic neurone activity. Neuropharmacology. 18: 845-9. PMID 551318 DOI: 10.1016/0028-3908(79)90080-7  0.418
1978 Pollard H, Llorens C, Bonnet JJ, Costentin J, Schwartz JC. Opiate receptors on mesolimbic dopaminergic neurons. Neuroscience Letters. 7: 295-9. PMID 19605129 DOI: 10.1016/0304-3940(78)90216-1  0.567
1978 Schwartz JC, Baudry M, Martres MP, Costentin J, Protais P. Increased in vivo binding of 3H-pimozide in mouse striatum following repeated administration of haloperidol. Life Sciences. 23: 1785-9. PMID 569235 DOI: 10.1016/0024-3205(78)90109-1  0.499
1978 Marcais H, Protais P, Costentin J, Schwartz JC. A gradual score to evaluate the climbing behaviour elicited by apomorphine in mice. Psychopharmacology. 56: 233-4. PMID 417378 DOI: 10.1007/Bf00431856  0.552
1978 Schwartz JC, Costentin J, Martres MP, Protais P, Baudry M. Modulation of receptor mechanisms in the CNS: hyper- and hyposensitivity to catecholamines. Neuropharmacology. 17: 665-85. PMID 211458 DOI: 10.1016/0028-3908(78)90080-1  0.464
1977 Baudry M, Costentin J, Marcais H, Martres MP, Protais P, Schwartz JC. Decreased responsiveness to low doses of apomorphine after dopamine agonists and the possible involvement of hyposensitivity of dopamine 'autoreceptors'. Neuroscience Letters. 4: 203-7. PMID 19604945 DOI: 10.1016/0304-3940(77)90139-2  0.601
1977 Martres MP, Costentin J, Baudry M, Marcais H, Protais P, Schwartz JC. Long-term changes in the sensitivity of pre-and postsynaptic dopamine receptors in mouse striatum evidenced by behavioural and biochemical studies. Brain Research. 136: 319-37. PMID 922486 DOI: 10.1016/0006-8993(77)90806-X  0.595
1977 Protais P, Costentin J, Schwartz JC. Climbing behavior induced by apomorphine in mice: a simple test for the study of dopamine receptors in striatum. Psychopharmacology. 50: 1-6. PMID 827755 DOI: 10.1007/Bf00634146  0.466
1977 Costentin J, Marçais H, Protais P, Baudry M, De La Baume S, Martres MP, Schwartz JC. Rapid development of hypersensitivity of striatal dopamine receptors induced by alpha-methylparatyrosine and its prevention by protein synthesis inhibitors. Life Sciences. 21: 307-13. PMID 561281 DOI: 10.1016/0024-3205(77)90510-0  0.556
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