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G. Ekin Atilla-Gokcumen - Publications

Affiliations: 
2003-2008 University of Pennsylvania, Philadelphia, PA, United States 
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13/66 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Wang SS, Gao X, Solar VD, Yu X, Antonopoulos A, Friedman AE, Matich EK, Atilla-Gokcumen GE, Nasirikenari M, Lau JT, Dell A, Haslam SM, Laine RA, Matta KL, Neelamegham S. Thioglycosides Are Efficient Metabolic Decoys of Glycosylation that Reduce Selectin Dependent Leukocyte Adhesion. Cell Chemical Biology. PMID 30344053 DOI: 10.1016/J.Chembiol.2018.09.012  0.302
2011 Feng L, Geisselbrecht Y, Blanck S, Wilbuer A, Atilla-Gokcumen GE, Filippakopoulos P, Kräling K, Celik MA, Harms K, Maksimoska J, Marmorstein R, Frenking G, Knapp S, Essen LO, Meggers E. Structurally sophisticated octahedral metal complexes as highly selective protein kinase inhibitors. Journal of the American Chemical Society. 133: 5976-86. PMID 21446733 DOI: 10.1021/Ja1112996  0.785
2011 Atilla-Gokcumen GE, Di Costanzo L, Meggers E. Structure of anticancer ruthenium half-sandwich complex bound to glycogen synthase kinase 3β. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 16: 45-50. PMID 20821241 DOI: 10.1007/S00775-010-0699-X  0.631
2010 Atilla-Gokcumen GE, Castoreno AB, Sasse S, Eggert US. Making the cut: the chemical biology of cytokinesis. Acs Chemical Biology. 5: 79-90. PMID 20014865 DOI: 10.1021/Cb900256M  0.32
2009 Meggers E, Atilla-Gokcumen GE, Gründler K, Frias C, Prokop A. Inert ruthenium half-sandwich complexes with anticancer activity. Dalton Transactions (Cambridge, England : 2003). 10882-8. PMID 20023918 DOI: 10.1039/B917792B  0.638
2008 Atilla-Gokcumen GE, Pagano N, Streu C, Maksimoska J, Filippakopoulos P, Knapp S, Meggers E. Extremely tight binding of a ruthenium complex to glycogen synthase kinase 3. Chembiochem : a European Journal of Chemical Biology. 9: 2933-6. PMID 19035373 DOI: 10.1002/Cbic.200800489  0.743
2008 Xie P, Williams DS, Atilla-Gokcumen GE, Milk L, Xiao M, Smalley KS, Herlyn M, Meggers E, Marmorstein R. Structure-based design of an organoruthenium phosphatidyl-inositol-3-kinase inhibitor reveals a switch governing lipid kinase potency and selectivity. Acs Chemical Biology. 3: 305-16. PMID 18484710 DOI: 10.1021/Cb800039Y  0.811
2008 Maksimoska J, Williams DS, Atilla-Gokcumen GE, Smalley KS, Carroll PJ, Webster RD, Filippakopoulos P, Knapp S, Herlyn M, Meggers E. Similar biological activities of two isostructural ruthenium and osmium complexes. Chemistry (Weinheim An Der Bergstrasse, Germany). 14: 4816-22. PMID 18425743 DOI: 10.1002/Chem.200800294  0.788
2008 Atilla-Gokcumen GE, Pagano N, Streu C, Maksimoska J, Filippakopoulos P, Knapp S, Meggers E. Cover Picture: Extremely Tight Binding of a Ruthenium Complex to Glycogen Synthase Kinase 3 (ChemBioChem 18/2008) Chembiochem. 9: 2897-2897. DOI: 10.1002/Cbic.200890070  0.757
2007 Smalley KS, Contractor R, Haass NK, Kulp AN, Atilla-Gokcumen GE, Williams DS, Bregman H, Flaherty KT, Soengas MS, Meggers E, Herlyn M. An organometallic protein kinase inhibitor pharmacologically activates p53 and induces apoptosis in human melanoma cells. Cancer Research. 67: 209-17. PMID 17210701 DOI: 10.1158/0008-5472.Can-06-1538  0.734
2007 Meggers E, Atilla-Gokcumen GE, Bregman H, Maksimoska J, Mulcahy SP, Pagano N, Williams DS. Exploring chemical space with organometallics: Ruthenium complexes as protein kinase inhibitors Synlett. 1177-1189. DOI: 10.1055/S-2007-973893  0.729
2007 Meggers E, Atilla-Gokcumen GE, Bregman H, Maksimoska J, Mulcahy SP, Pagano N, Williams DS. Exploring Chemical Space with Organometallics: Ruthenium Complexes as Protein Kinase Inhibitors Cheminform. 38. DOI: 10.1002/chin.200731205  0.785
2006 Atilla-Gokcumen GE, Williams DS, Bregman H, Pagano N, Meggers E. Organometallic compounds with biological activity: a very selective and highly potent cellular inhibitor for glycogen synthase kinase 3. Chembiochem : a European Journal of Chemical Biology. 7: 1443-50. PMID 16858717 DOI: 10.1002/Cbic.200600117  0.78
Low-probability matches (unlikely to be authored by this person)
2017 Lizardo DY, Parisi L, Li N, Atilla-Gokcumen GE. Non-canonical Roles of Lipids in Different Cellular Fates. Biochemistry. PMID 29019646 DOI: 10.1021/Acs.Biochem.7B00862  0.298
2016 Li N, Lizardo DY, Atilla-Gokcumen GE. Specific Triacylglycerols Accumulate via Increased Lipogenesis During 5-FU-induced Apoptosis. Acs Chemical Biology. PMID 27428610 DOI: 10.1021/Acschembio.6B00410  0.293
2018 Parisi LR, Morrow LM, Visser MB, Atilla-Gokcumen GE. Turning the spotlight on lipids in non-apoptotic cell death. Acs Chemical Biology. PMID 29376324 DOI: 10.1021/Acschembio.7B01082  0.293
2014 Muro E, Atilla-Gokcumen GE, Eggert US. Lipids in cell biology: how can we understand them better? Molecular Biology of the Cell. 25: 1819-23. PMID 24925915 DOI: 10.1091/Mbc.E13-09-0516  0.288
2019 Matich EK, Chavez Soria NG, Aga DS, Atilla-Gokcumen GE. Applications of metabolomics in assessing ecological effects of emerging contaminants and pollutants on plants. Journal of Hazardous Materials. 373: 527-535. PMID 30951997 DOI: 10.1016/J.Jhazmat.2019.02.084  0.285
2014 Atilla-Gokcumen GE, Muro E, Relat-Goberna J, Sasse S, Bedigian A, Coughlin ML, Garcia-Manyes S, Eggert US. Dividing cells regulate their lipid composition and localization. Cell. 156: 428-39. PMID 24462247 DOI: 10.1016/J.Cell.2013.12.015  0.281
2020 Swayambhu G, Moscatello N, Atilla-Gokcumen GE, Pfeifer BA. Flux Balance Analysis for Media Optimization and Genetic Targets to Improve Heterologous Siderophore Production. Iscience. 23: 101016. PMID 32279062 DOI: 10.1016/J.Isci.2020.101016  0.276
2015 Del Solar V, Lizardo DY, Li N, Hurst JJ, Brais CJ, Atilla-Gokcumen GE. Differential Regulation of Specific Sphingolipids in Colon Cancer Cells during Staurosporine-Induced Apoptosis. Chemistry & Biology. 22: 1662-70. PMID 26687483 DOI: 10.1016/J.Chembiol.2015.11.004  0.274
2020 Millner A, Atilla-Gokcumen GE. Lipid Players of Cellular Senescence. Metabolites. 10: 339. PMID 32839400 DOI: 10.3390/Metabo10090339  0.273
2022 Millner A, Running L, Colon-Rosa N, Aga DS, Frasor J, Atilla-Gokcumen GE. Ceramide-1-Phosphate Is Involved in Therapy-Induced Senescence. Acs Chemical Biology. PMID 35353506 DOI: 10.1021/acschembio.2c00216  0.272
2020 Bozelli JC, Lu D, Atilla-Gokcumen GE, Epand RM. Promotion of plasmalogen biosynthesis reverse lipid changes in a Barth Syndrome cell model. Biochimica Et Biophysica Acta. Molecular and Cell Biology of Lipids. 158677. PMID 32126285 DOI: 10.1016/J.Bbalip.2020.158677  0.263
2015 Singh RR, Lester Y, Linden KG, Love NG, Atilla-Gokcumen GE, Aga DS. Application of metabolite profiling tools and time-of-flight mass spectrometry in the identification of transformation products of iopromide and iopamidol during advanced oxidation. Environmental Science & Technology. 49: 2983-90. PMID 25651339 DOI: 10.1021/Es505469H  0.262
2017 Lizardo DY, Lin YL, Gokcumen O, Atilla-Gokcumen GE. Regulation of lipids is central to replicative senescence. Molecular Biosystems. PMID 28128379 DOI: 10.1039/C6Mb00842A  0.258
2019 Parisi LR, Sowlati-Hashjin S, Berhane IA, Galster SL, Carter KA, Lovell JF, Chemler SR, Karttunen M, Atilla-Gokcumen GE. Membrane disruption by very long chain fatty acids during necroptosis. Acs Chemical Biology. PMID 31490656 DOI: 10.1021/Acschembio.9B00616  0.257
2016 Matich EK, Butryn DM, Ghafari M, del Solar V, Camgoz E, Pfeifer BA, Aga DS, Haznedaroglu BZ, Atilla-Gokcumen GE. Mass spectrometry-based metabolomics of value-added biochemicals from Ettlia oleoabundans Algal Research. 19: 146-154. DOI: 10.1016/J.Algal.2016.08.009  0.25
2018 Li N, Sancak Y, Frasor J, Atilla-Gokcumen GE. A Protective Role for Triacylglycerols during Apoptosis. Biochemistry. 57: 72-80. PMID 29188717 DOI: 10.1021/Acs.Biochem.7B00975  0.249
2023 Ramirez RX, Campbell O, Pradhan AJ, Atilla-Gokcumen GE, Monje-Galvan V. Modeling the molecular fingerprint of protein-lipid interactions of MLKL on complex bilayers. Frontiers in Chemistry. 10: 1088058. PMID 36712977 DOI: 10.3389/fchem.2022.1088058  0.244
2016 Mondal N, Stolfa G, Antonopoulos A, Zhu Y, Wang SS, Buffone A, Atilla-Gokcumen GE, Haslam SM, Dell A, Neelamegham S. Glycosphingolipids on Human Myeloid Cells Stabilize E-Selectin-Dependent Rolling in the Multistep Leukocyte Adhesion Cascade. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 26868209 DOI: 10.1161/Atvbaha.115.306748  0.244
2021 Pradhan AJ, Lu D, Parisi LR, Shen S, Berhane IA, Galster SL, Bynum K, Monje-Galvan V, Gokcumen O, Chemler SR, Qu J, Kay JG, Atilla-Gokcumen GE. Protein acylation by saturated very long chain fatty acids and endocytosis are involved in necroptosis. Cell Chemical Biology. PMID 33848465 DOI: 10.1016/j.chembiol.2021.03.012  0.244
2017 Parisi LR, Li N, Atilla-Gokcumen GE. Very Long Chain Fatty Acids Are Functionally Involved in Necroptosis. Cell Chemical Biology. 24: 1445-1454.e8. PMID 29033315 DOI: 10.1016/J.Chembiol.2017.08.026  0.241
2017 Luo D, Geng J, Li N, Carter KA, Shao S, Atilla-Gokcumen GE, Lovell JF. Vessel-Targeted Chemophototherapy with Cationic Porphyrin-Phospholipid Liposomes. Molecular Cancer Therapeutics. PMID 28729400 DOI: 10.1158/1535-7163.Mct-17-0276  0.238
2015 Atilla-Gokcumen GE, Eggert US. A comparative LC-MS based profiling approach to analyze lipid composition in tissue culture systems. Methods in Molecular Biology (Clifton, N.J.). 1232: 103-13. PMID 25331131 DOI: 10.1007/978-1-4939-1752-5_9  0.234
2023 Pradhan AJ, Atilla-Gokcumen GE. Omics approaches to better understand the molecular mechanism of necroptosis and their translational implications. Molecular Omics. PMID 36655911 DOI: 10.1039/d2mo00318j  0.233
2015 Horner IJ, Kraut ND, Hurst JJ, Rook AM, Collado CM, Atilla-Gokcumen GE, Maziarz EP, Liu XM, Merchea MM, Bright FV. Effects of Polyhexamethylene Biguanide and Polyquaternium-1 on Phospholipid Bilayer Structure and Dynamics. The Journal of Physical Chemistry. B. PMID 26239890 DOI: 10.1021/Acs.Jpcb.5B07162  0.231
2019 Chavez Soria NG, Bisson MA, Atilla-Gokcumen GE, Aga DS. High-resolution mass spectrometry-based metabolomics reveal the disruption of jasmonic pathway in Arabidopsis thaliana upon copper oxide nanoparticle exposure. The Science of the Total Environment. 693: 133443. PMID 31362232 DOI: 10.1016/J.Scitotenv.2019.07.249  0.227
2016 Luo D, Li N, Carter KA, Lin C, Geng J, Shao S, Huang WC, Qin Y, Atilla-Gokcumen GE, Lovell JF. Rapid Light-Triggered Drug Release in Liposomes Containing Small Amounts of Unsaturated and Porphyrin-Phospholipids. Small (Weinheim An Der Bergstrasse, Germany). PMID 27121003 DOI: 10.1002/Smll.201503966  0.226
2017 Chavez Soria NG, Montes A, Bisson MA, Atilla-Gokcumen GE, Aga DS. Mass spectrometry-based metabolomics to assess uptake of silver nanoparticles by Arabidopsis thaliana Environmental Science: Nano. 4: 1944-1953. DOI: 10.1039/C7En00555E  0.213
2024 Pradhan AJ, Chitkara S, Ramirez RX, Monje-Galvan V, Sancak Y, Atilla-Gokcumen GE. Acylation of MLKL Impacts Its Function in Necroptosis. Acs Chemical Biology. PMID 38301282 DOI: 10.1021/acschembio.3c00603  0.209
2017 Miranda D, Carter K, Luo D, Shao S, Geng J, Li C, Chitgupi U, Turowski SG, Li N, Atilla-Gokcumen GE, Spernyak JA, Lovell JF. Multifunctional Liposomes for Image-Guided Intratumoral Chemo-Phototherapy. Advanced Healthcare Materials. PMID 28504409 DOI: 10.1002/Adhm.201700253  0.202
2023 Pradhan AJ, Chitkara S, Ramirez RX, Monje-Galvan V, Sancak Y, Atilla-Gokcumen GE. Acylation of MLKL impacts its function in necroptosis. Biorxiv : the Preprint Server For Biology. PMID 37645912 DOI: 10.1101/2023.08.19.553906  0.197
2022 Vilas-Boas C, Running L, Pereira D, Cidade H, Correia-da-Silva M, Atilla-Gokcumen GE, Aga DS. Impact of Tralopyril and Triazolyl Glycosylated Chalcone in Human Retinal Cells' Lipidome. Molecules (Basel, Switzerland). 27. PMID 36014486 DOI: 10.3390/molecules27165247  0.179
2011 Atilla-Gokcumen GE, Bedigian AV, Sasse S, Eggert US. Inhibition of glycosphingolipid biosynthesis induces cytokinesis failure. Journal of the American Chemical Society. 133: 10010-3. PMID 21668028 DOI: 10.1021/ja202804b  0.179
2023 Lu D, Parisi LR, Gokcumen O, Atilla-Gokcumen GE. SREBP activation contributes to fatty acid accumulations in necroptosis. Rsc Chemical Biology. 4: 310-322. PMID 37034406 DOI: 10.1039/d2cb00172a  0.171
2019 Li N, Saitou M, Atilla-Gokcumen GE. The Role of p38 MAPK in Triacylglycerol Accumulation During Apoptosis. Proteomics. e1900160. PMID 31099964 DOI: 10.1002/pmic.201900160  0.159
2021 Pliss A, Kuzmin AN, Lita A, Kumar R, Celiku O, Atilla-Gokcumen GE, Gokcumen O, Chandra D, Larion M, Prasad PN. A Single-Organelle Optical Omics Platform for Cell Science and Biomarker Discovery. Analytical Chemistry. 93: 8281-8290. PMID 34048235 DOI: 10.1021/acs.analchem.1c01131  0.144
2022 Pal P, Millner A, Semina SE, Huggins RJ, Running L, Aga DS, Tonetti DA, Schiff R, Greene GL, Atilla-Gokcumen GE, Frasor J. Endocrine Therapy-Resistant Breast Cancer Cells Are More Sensitive to Ceramide Kinase Inhibition and Elevated Ceramide Levels Than Therapy-Sensitive Breast Cancer Cells. Cancers. 14. PMID 35625985 DOI: 10.3390/cancers14102380  0.141
2020 Millner A, Lizardo DY, Atilla-Gokcumen GE. Untargeted Lipidomics Highlight the Depletion of Deoxyceramides during Therapy-Induced Senescence. Proteomics. 20: e2000013. PMID 32267073 DOI: 10.1002/pmic.202000013  0.14
2018 Brovkovych V, Izhar Y, Danes JM, Dubrovskyi O, Sakallioglu IT, Morrow LM, Atilla-Gokcumen GE, Frasor J. Fatostatin induces pro- and anti-apoptotic lipid accumulation in breast cancer. Oncogenesis. 7: 66. PMID 30140005 DOI: 10.1038/s41389-018-0076-0  0.137
2020 Bayraktar EC, La K, Karpman K, Unlu G, Ozerdem C, Ritter DJ, Alwaseem H, Molina H, Hoffmann HH, Millner A, Atilla-Gokcumen GE, Gamazon ER, Rushing AR, Knapik EW, Basu S, et al. Metabolic coessentiality mapping identifies C12orf49 as a regulator of SREBP processing and cholesterol metabolism. Nature Metabolism. 2: 487-498. PMID 32694732 DOI: 10.1038/s42255-020-0206-9  0.135
2023 Camdzic M, Aga DS, Atilla-Gokcumen GE. Cellular Lipidome Changes during Retinoic Acid (RA)-Induced Differentiation in SH-SY5Y Cells: A Comprehensive Model for Assessing Neurotoxicity of Contaminants. Environment & Health (Washington, D.C.). 1: 110-120. PMID 37614295 DOI: 10.1021/envhealth.3c00022  0.13
2021 Millner A, Atilla-Gokcumen GE. Solving the enigma: Mass spectrometry and small molecule probes to study sphingolipid function. Current Opinion in Chemical Biology. 65: 49-56. PMID 34175552 DOI: 10.1016/j.cbpa.2021.05.001  0.128
2022 Camdzic M, Aga DS, Atilla-Gokcumen GE. Cellular Interactions and Fatty Acid Transporter CD36-Mediated Uptake of Per- and Polyfluorinated Alkyl Substances (PFAS). Chemical Research in Toxicology. 35: 694-702. PMID 35380827 DOI: 10.1021/acs.chemrestox.2c00078  0.124
2021 Morstein J, Kol M, Novak AJE, Feng S, Khayyo S, Hinnah K, Li-Purcell N, Pan G, Williams BM, Riezman H, Atilla-Gokcumen GE, Holthuis JCM, Trauner D. Short Photoswitchable Ceramides Enable Optical Control of Apoptosis. Acs Chemical Biology. PMID 33586946 DOI: 10.1021/acschembio.0c00823  0.123
2021 Kilian HI, Pradhan AJ, Jahagirdar D, Ortega J, Atilla-Gokcumen GE, Lovell JF. Light-Triggered Release of Large Biomacromolecules from Porphyrin-Phospholipid Liposomes. Langmuir : the Acs Journal of Surfaces and Colloids. PMID 34450021 DOI: 10.1021/acs.langmuir.1c01848  0.119
2019 Chavez Soria NG, Aga DS, Atilla-Gokcumen GE. Lipidomics reveals insights on the biological effects of copper oxide nanoparticles in a human colon carcinoma cell line. Molecular Omics. 15: 30-38. PMID 30560257 DOI: 10.1039/c8mo00162f  0.114
2018 Matich EK, Ghafari M, Camgoz E, Caliskan E, Pfeifer BA, Haznedaroglu BZ, Atilla-Gokcumen GE. Time-series lipidomic analysis of the oleaginous green microalga speciesunder nutrient stress. Biotechnology For Biofuels. 11: 29. PMID 29441127 DOI: 10.1186/S13068-018-1026-Y  0.113
2018 Saitou M, Lizardo DY, Taskent RO, Millner A, Gokcumen O, Atilla-Gokcumen GE. An evolutionary transcriptomics approach links CD36 to membrane remodeling in replicative senescence. Molecular Omics. PMID 29974107 DOI: 10.1039/c8mo00099a  0.11
2023 Zoodsma JD, Boonkanon C, Running L, Basharat R, Atilla-Gokcumen GE, Aga DS, Sirotkin HI. PFOS impacts complex behaviors in larval zebrafish. Environmental Toxicology and Chemistry. PMID 38153236 DOI: 10.1002/etc.5819  0.104
2022 Pal P, Atilla-Gokcumen GE, Frasor J. Emerging Roles of Ceramides in Breast Cancer Biology and Therapy. International Journal of Molecular Sciences. 23. PMID 36232480 DOI: 10.3390/ijms231911178  0.082
2022 Running L, Atilla-Gokcumen GE, Aga DS. Development of a Liquid Chromatography-Mass Spectrometry-Based In Vitro Assay to Assess Changes in Steroid Hormones Due to Exposure to Per- and Polyfluoroalkyl Substances. Chemical Research in Toxicology. PMID 35696490 DOI: 10.1021/acs.chemrestox.2c00116  0.069
2021 Saitou M, Resendez S, Pradhan AJ, Wu F, Lie NC, Hall NJ, Zhu Q, Reinholdt L, Satta Y, Speidel L, Nakagome S, Hanchard NA, Churchill G, Lee C, Atilla-Gokcumen GE, et al. Sex-specific phenotypic effects and evolutionary history of an ancient polymorphic deletion of the human growth hormone receptor. Science Advances. 7: eabi4476. PMID 34559564 DOI: 10.1126/sciadv.abi4476  0.033
2020 Atilla-Gokcumen GE. Special Issue on Lipidomics. Proteomics. 19: e1900243. PMID 31420925 DOI: 10.1002/pmic.201900243  0.025
2018 Miranda D, Li N, Li C, Stefanovic F, Atilla-Gokcumen GE, Lovell JF. Detection of Sunlight Exposure with Solar-Sensitive Liposomes that Capture and Release Food Dyes Acs Applied Nano Materials. 1: 2739-2747. DOI: 10.1021/acsanm.8b00435  0.018
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