| Year | Citation | Score | |||
|---|---|---|---|---|---|
| 2019 | Celetti G, Paci G, Caria J, VanDelinder V, Bachand G, Lemke EA. The liquid state of FG-nucleoporins mimics permeability barrier properties of nuclear pore complexes. The Journal of Cell Biology. PMID 31723007 DOI: 10.1083/jcb.201907157 | 1 | |||
| 2019 | Chowdhury A, Yu M, Lemke EA. Phase Separation Comes of Age: From Phenomenology to Single Molecules. Molecular Cell. 74: 413-415. PMID 31051137 DOI: 10.1016/j.molcel.2019.04.016 | 0.6 | |||
| 2019 | Lu M, Ma X, Castillo-Menendez LR, Gorman J, Alsahafi N, Ermel U, Terry DS, Chambers M, Peng D, Zhang B, Zhou T, Reichard N, Wang K, Grover JR, Carman BP, ... ... Lemke EA, et al. Associating HIV-1 envelope glycoprotein structures with states on the virus observed by smFRET. Nature. PMID 30971821 DOI: 10.1038/s41586-019-1101-y | 0.36 | |||
| 2019 | Reinkemeier CD, Girona GE, Lemke EA. Designer membraneless organelles enable codon reassignment of selected mRNAs in eukaryotes. Science (New York, N.Y.). 363. PMID 30923194 DOI: 10.1126/science.aaw2644 | 0.76 | |||
| 2019 | Lemke EA, Chowdhury A, Kovalenko SA, Aramburu IV, Tan PS, Ernsting NP. Mechanism dependent modulation of ultrafast interfacial water dynamics in intrinsically disordered protein complexes. Angewandte Chemie (International Ed. in English). PMID 30703278 DOI: 10.1002/anie.201813354 | 0.76 | |||
| 2018 | Tan PS, Lemke EA. Probing Differential Binding Mechanisms of Phenylalanine-Glycine-Rich Nucleoporins by Single-Molecule FRET. Methods in Enzymology. 611: 327-346. PMID 30471692 DOI: 10.1016/bs.mie.2018.08.034 | 0.32 | |||
| 2018 | Fuertes G, Banterle N, Ruff KM, Chowdhury A, Pappu RV, Svergun DI, Lemke EA. Comment on "Innovative scattering analysis shows that hydrophobic disordered proteins are expanded in water". Science (New York, N.Y.). 361. PMID 30166461 DOI: 10.1126/science.aau8230 | 0.6 | |||
| 2018 | Mikhaleva S, Lemke EA. Beyond the Transport Function of Import Receptors: What's All the FUS about? Cell. 173: 549-553. PMID 29677508 DOI: 10.1016/j.cell.2018.04.002 | 0.44 | |||
| 2018 | Kormos A, Koehler C, Fodor E, Rutkai Z, Martin M, Mező G, Lemke E, Kele P. Bistetrazine-cyanines as double-clicking fluorogenic two-point binder or crosslinker probes. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 29676491 DOI: 10.1002/chem.201800910 | 0.44 | |||
| 2018 | Tan PS, Aramburu IV, Mercadante D, Tyagi S, Chowdhury A, Spitz D, Shammas SL, Gräter F, Lemke EA. Two Differential Binding Mechanisms of FG-Nucleoporins and Nuclear Transport Receptors. Cell Reports. 22: 3660-3671. PMID 29590630 DOI: 10.1016/j.celrep.2018.03.022 | 0.76 | |||
| 2018 | Kozma E, Paci G, Estrada Girona G, Lemke EA, Kele P. Fluorogenic Tetrazine-Siliconrhodamine Probe for the Labeling of Noncanonical Amino Acid Tagged Proteins. Methods in Molecular Biology (Clifton, N.J.). 1728: 337-363. PMID 29405009 DOI: 10.1007/978-1-4939-7574-7_22 | 1 | |||
| 2018 | Koehler C, Lemke EA. MultiBacTAG-Genetic Code Expansion Using the Baculovirus Expression System in Sf21 Cells. Methods in Molecular Biology (Clifton, N.J.). 1728: 297-311. PMID 29405006 DOI: 10.1007/978-1-4939-7574-7_19 | 0.44 | |||
| 2017 | Gupta K, Watson AA, Baptista T, Scheer E, Chambers AL, Koehler C, Zou J, Obong-Ebong I, Kandiah E, Temblador A, Round A, Forest E, Man P, Bieniossek C, Laue ED, ... Lemke EA, et al. Architecture of TAF11/TAF13/TBP complex suggests novel regulation properties of general transcription factor TFIID. Elife. 6. PMID 29111974 DOI: 10.7554/eLife.30395 | 0.44 | |||
| 2017 | Warner JB, Ruff K, Tan PS, Lemke EA, Pappu RV, Lashuel HA. Monomeric huntingtin exon 1 has similar overall structural features for wild type and pathological polyglutamine lengths. Journal of the American Chemical Society. PMID 28937758 DOI: 10.1021/jacs.7b06659 | 0.32 | |||
| 2017 | Mercadante D, Wagner JA, Aramburu IV, Lemke EA, Gräter F. Sampling long versus short range interactions defines the ability of force fields to reproduce the dynamics of intrinsically disordered proteins. Journal of Chemical Theory and Computation. PMID 28805390 DOI: 10.1021/acs.jctc.7b00143 | 0.76 | |||
| 2017 | Fuertes G, Banterle N, Ruff KM, Chowdhury A, Mercadante D, Koehler C, Kachala M, Estrada Girona G, Milles S, Mishra A, Onck PR, Gräter F, Esteban-Martín S, Pappu RV, Svergun DI, ... Lemke EA, et al. Decoupling of size and shape fluctuations in heteropolymeric sequences reconciles discrepancies in SAXS vs. FRET measurements. Proceedings of the National Academy of Sciences of the United States of America. PMID 28716919 DOI: 10.1073/pnas.1704692114 | 0.6 | |||
| 2017 | Aramburu IV, Lemke EA. Floppy but not sloppy: Interaction mechanism of FG-Nucleoporins and nuclear transport receptors. Seminars in Cell & Developmental Biology. PMID 28669824 DOI: 10.1016/j.semcdb.2017.06.026 | 0.76 | |||
| 2017 | Sakin V, Hanne J, Dunder J, Anders-Össwein M, Laketa V, Nikić I, Kräusslich HG, Lemke EA, Müller B. A Versatile Tool for Live-Cell Imaging and Super-Resolution Nanoscopy Studies of HIV-1 Env Distribution and Mobility. Cell Chemical Biology. PMID 28457706 DOI: 10.1016/j.chembiol.2017.04.007 | 0.6 | |||
| 2017 | Demeter O, Kormos A, Koehler C, Mezõ G, Németh K, Kozma E, Takacs L, Lemke EA, Kele P. BISAZIDE CYANINE DYES AS FLUOROGENIC PROBES FOR BIS-CYCLOOCTYNYLATED PEPTIDE TAGS AND AS FLUOROGENIC CROSSLINKERS OF CYCLOOCTYNYLATED PROTEINS. Bioconjugate Chemistry. PMID 28441009 DOI: 10.1021/acs.bioconjchem.7b00178 | 0.44 | |||
| 2017 | Paci G, Lemke EA. Shining a Light on Phase Separation in the Cell. Cell. 168: 11-13. PMID 28086083 DOI: 10.1016/j.cell.2016.12.018 | 1 | |||
| 2016 | Nikić I, Estrada Girona G, Kang JH, Paci G, Mikhaleva S, Koehler C, Shymanska NV, Ventura Santos C, Spitz D, Lemke EA. Debugging Eukaryotic Genetic Code Expansion for Site-Specific Click-PAINT Super-Resolution Microscopy. Angewandte Chemie (International Ed. in English). PMID 27804198 DOI: 10.1002/anie.201608284 | 1 | |||
| 2016 | Koehler C, Sauter PF, Wawryszyn M, Girona GE, Gupta K, Landry JJ, Fritz MH, Radic K, Hoffmann JE, Chen ZA, Zou J, Tan PS, Galik B, Junttila S, Stolt-Bergner P, ... ... Lemke EA, et al. Genetic code expansion for multiprotein complex engineering. Nature Methods. PMID 27749839 DOI: 10.1038/nmeth.4032 | 0.76 | |||
| 2016 | Kozma E, Nikic I, Varga BR, Aramburu IV, Kang JH, Fackler OT, Lemke EA, Kele P. Hydrophilic trans-Cyclooctenylated Non-Canonical Amino Acids for Fast Intracellular Protein Labeling. Chembiochem : a European Journal of Chemical Biology. PMID 27223658 DOI: 10.1002/cbic.201600284 | 1 | |||
| 2016 | Knorr G, Kozma E, Herner A, Lemke EA, Kele P. New Red-Emitting Tetrazine-Phenoxazine Fluorogenic Labels for Live-Cell Intracellular Bioorthogonal Labeling Schemes. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 27218228 DOI: 10.1002/chem.201600590 | 1 | |||
| 2016 | Sakin V, Paci G, Lemke EA, Müller B. Labeling of virus components for advanced, quantitative imaging analyses. Febs Letters. PMID 26987299 DOI: 10.1002/1873-3468.12131 | 1 | |||
| 2015 | Vreja IC, Nikić I, Göttfert F, Bates M, Kröhnert K, Outeiro TF, Hell SW, Lemke EA, Rizzoli SO. Super-resolution Microscopy of Clickable Amino Acids Reveals the Effects of Fluorescent Protein Tagging on Protein Assemblies. Acs Nano. PMID 26498474 DOI: 10.1021/acsnano.5b04434 | 1 | |||
| 2015 | Milles S, Mercadante D, Aramburu IV, Jensen MR, Banterle N, Koehler C, Tyagi S, Clarke J, Shammas SL, Blackledge M, Gräter F, Lemke EA. Plasticity of an Ultrafast Interaction between Nucleoporins and Nuclear Transport Receptors. Cell. 163: 734-45. PMID 26456112 DOI: 10.1016/j.cell.2015.09.047 | 1 | |||
| 2015 | Delaforge E, Milles S, Bouvignies G, Bouvier D, Boivin S, Salvi N, Maurin D, Martel A, Round A, Lemke EA, Ringkjøbing Jensen M, Hart DJ, Blackledge M. Large-Scale Conformational Dynamics Control H5N1 Influenza Polymerase PB2 Binding to Importin α. Journal of the American Chemical Society. PMID 26424125 DOI: 10.1021/jacs.5b07765 | 1 | |||
| 2015 | von Appen A, Kosinski J, Sparks L, Ori A, DiGuilio AL, Vollmer B, Mackmull MT, Banterle N, Parca L, Kastritis P, Buczak K, Mosalaganti S, Hagen W, Andres-Pons A, Lemke EA, et al. In situ structural analysis of the human nuclear pore complex. Nature. 526: 140-3. PMID 26416747 DOI: 10.1038/nature15381 | 1 | |||
| 2015 | Nikić I, Lemke EA. Genetic code expansion enabled site-specific dual-color protein labeling: superresolution microscopy and beyond. Current Opinion in Chemical Biology. 28: 164-73. PMID 26302384 DOI: 10.1016/j.cbpa.2015.07.021 | 0.44 | |||
| 2015 | Wagner JA, Mercadante D, Nikić I, Lemke EA, Gräter F. Origin of Orthogonality of Strain-Promoted Click Reactions. Chemistry (Weinheim An Der Bergstrasse, Germany). 21: 12431-5. PMID 26178299 DOI: 10.1002/chem.201501727 | 0.44 | |||
| 2015 | Hoffmann JE, Plass T, Nikić I, Aramburu IV, Koehler C, Gillandt H, Lemke EA, Schultz C. Highly Stable trans-Cyclooctene Amino Acids for Live-Cell Labeling. Chemistry (Weinheim An Der Bergstrasse, Germany). 21: 12266-70. PMID 26177861 DOI: 10.1002/chem.201501647 | 1 | |||
| 2015 | Mercadante D, Milles S, Fuertes G, Svergun DI, Lemke EA, Gräter F. Kirkwood-Buff Approach Rescues Overcollapse of a Disordered Protein in Canonical Protein Force Fields. The Journal of Physical Chemistry. B. 119: 7975-84. PMID 26030189 DOI: 10.1021/acs.jpcb.5b03440 | 0.44 | |||
| 2015 | Niki? I, Kang JH, Girona GE, Aramburu IV, Lemke EA. Labeling proteins on live mammalian cells using click chemistry. Nature Protocols. 10: 780-91. PMID 25906116 DOI: 10.1038/nprot.2015.045 | 0.76 | |||
| 2015 | Tyagi S, Lemke EA. Single-molecule FRET and crosslinking studies in structural biology enabled by noncanonical amino acids. Current Opinion in Structural Biology. 32: 66-73. PMID 25757192 DOI: 10.1016/j.sbi.2015.02.009 | 1 | |||
| 2014 | Dunne M, Mertens HD, Garefalaki V, Jeffries CM, Thompson A, Lemke EA, Svergun DI, Mayer MJ, Narbad A, Meijers R. The CD27L and CTP1L endolysins targeting Clostridia contain a built-in trigger and release factor. Plos Pathogens. 10: e1004228. PMID 25058163 DOI: 10.1371/journal.ppat.1004228 | 1 | |||
| 2014 | Herner A, Estrada Girona G, Nikić I, Kállay M, Lemke EA, Kele P. New generation of bioorthogonally applicable fluorogenic dyes with visible excitations and large Stokes shifts. Bioconjugate Chemistry. 25: 1370-4. PMID 24932756 DOI: 10.1021/bc500235p | 1 | |||
| 2014 | Milles S, Lemke EA. Mapping multivalency and differential affinities within large intrinsically disordered protein complexes with segmental motion analysis. Angewandte Chemie (International Ed. in English). 53: 7364-7. PMID 24898547 DOI: 10.1002/anie.201403694 | 0.44 | |||
| 2014 | Pavic K, Rios P, Dzeyk K, Koehler C, Lemke EA, Köhn M. Unnatural amino acid mutagenesis reveals dimerization as a negative regulatory mechanism of VHR's phosphatase activity. Acs Chemical Biology. 9: 1451-9. PMID 24798147 DOI: 10.1021/cb500240n | 0.44 | |||
| 2014 | Nikić I, Plass T, Schraidt O, Szymański J, Briggs JA, Schultz C, Lemke EA. Minimal tags for rapid dual-color live-cell labeling and super-resolution microscopy. Angewandte Chemie (International Ed. in English). 53: 2245-9. PMID 24474648 DOI: 10.1002/anie.201309847 | 1 | |||
| 2014 | Tyagi S, VanDelinder V, Banterle N, Fuertes G, Milles S, Agez M, Lemke EA. Continuous throughput and long-term observation of single-molecule FRET without immobilization. Nature Methods. 11: 297-300. PMID 24441935 DOI: 10.1038/nmeth.2809 | 0.68 | |||
| 2013 | Herner A, Nikić I, Kállay M, Lemke EA, Kele P. A new family of bioorthogonally applicable fluorogenic labels. Organic & Biomolecular Chemistry. 11: 3297-306. PMID 23535909 DOI: 10.1039/c3ob40296g | 1 | |||
| 2013 | Ori A, Banterle N, Iskar M, Andrés-Pons A, Escher C, Khanh Bui H, Sparks L, Solis-Mezarino V, Rinner O, Bork P, Lemke EA, Beck M. Cell type-specific nuclear pores: a case in point for context-dependent stoichiometry of molecular machines. Molecular Systems Biology. 9: 648. PMID 23511206 DOI: 10.1038/msb.2013.4 | 1 | |||
| 2013 | LukinaviÄius G, Umezawa K, Olivier N, Honigmann A, Yang G, Plass T, Mueller V, Reymond L, Corrêa IR, Luo ZG, Schultz C, Lemke EA, Heppenstall P, Eggeling C, Manley S, et al. A near-infrared fluorophore for live-cell super-resolution microscopy of cellular proteins. Nature Chemistry. 5: 132-9. PMID 23344448 DOI: 10.1038/nchem.1546 | 1 | |||
| 2013 | Tyagi S, Lemke EA. Genetically encoded click chemistry for single-molecule FRET of proteins. Methods in Cell Biology. 113: 169-87. PMID 23317903 DOI: 10.1016/B978-0-12-407239-8.00009-4 | 1 | |||
| 2013 | Milles S, Huy Bui K, Koehler C, Eltsov M, Beck M, Lemke EA. Facilitated aggregation of FG nucleoporins under molecular crowding conditions. Embo Reports. 14: 178-83. PMID 23238392 DOI: 10.1038/embor.2012.204 | 0.44 | |||
| 2013 | Milles S, Lemke EA. What precision-protein-tuning and nano-resolved single molecule sciences can do for each other. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 35: 65-74. PMID 23147190 DOI: 10.1002/bies.201200094 | 0.44 | |||
| 2012 | Borrmann A, Milles S, Plass T, Dommerholt J, Verkade JM, Wiessler M, Schultz C, van Hest JC, van Delft FL, Lemke EA. Genetic encoding of a bicyclo[6.1.0]nonyne-charged amino acid enables fast cellular protein imaging by metal-free ligation. Chembiochem : a European Journal of Chemical Biology. 13: 2094-9. PMID 22945333 DOI: 10.1002/cbic.201200407 | 0.44 | |||
| 2012 | Krishnan R, Goodman JL, Mukhopadhyay S, Pacheco CD, Lemke EA, Deniz AA, Lindquist S. Conserved features of intermediates in amyloid assembly determine their benign or toxic states. Proceedings of the National Academy of Sciences of the United States of America. 109: 11172-7. PMID 22745165 DOI: 10.1073/pnas.1209527109 | 1 | |||
| 2012 | Milles S, Koehler C, Gambin Y, Deniz AA, Lemke EA. Intramolecular three-colour single pair FRET of intrinsically disordered proteins with increased dynamic range. Molecular Biosystems. 8: 2531-4. PMID 22739670 DOI: 10.1039/c2mb25135c | 1 | |||
| 2012 | Plass T, Milles S, Koehler C, Szymański J, Mueller R, Wiessler M, Schultz C, Lemke EA. Amino acids for Diels-Alder reactions in living cells. Angewandte Chemie (International Ed. in English). 51: 4166-70. PMID 22473599 DOI: 10.1002/anie.201108231 | 0.44 | |||
| 2012 | Milles S, Tyagi S, Banterle N, Koehler C, VanDelinder V, Plass T, Neal AP, Lemke EA. Click strategies for single-molecule protein fluorescence. Journal of the American Chemical Society. 134: 5187-95. PMID 22356317 DOI: 10.1021/ja210587q | 1 | |||
| 2011 | Milles S, Lemke EA. Single molecule study of the intrinsically disordered FG-repeat nucleoporin 153. Biophysical Journal. 101: 1710-9. PMID 21961597 DOI: 10.1016/j.bpj.2011.08.025 | 0.44 | |||
| 2011 | Plass T, Milles S, Koehler C, Schultz C, Lemke EA. Genetically encoded copper-free click chemistry. Angewandte Chemie (International Ed. in English). 50: 3878-81. PMID 21433234 DOI: 10.1002/anie.201008178 | 0.44 | |||
| 2011 | Gambin Y, VanDelinder V, Ferreon AC, Lemke EA, Groisman A, Deniz AA. Visualizing a one-way protein encounter complex by ultrafast single-molecule mixing. Nature Methods. 8: 239-41. PMID 21297620 DOI: 10.1038/nmeth.1568 | 1 | |||
| 2009 | Lemke EA, Gambin Y, Vandelinder V, Brustad EM, Liu HW, Schultz PG, Groisman A, Deniz AA. Microfluidic device for single-molecule experiments with enhanced photostability. Journal of the American Chemical Society. 131: 13610-2. PMID 19772358 DOI: 10.1021/ja9027023 | 1 | |||
| 2009 | Lee HS, Guo J, Lemke EA, Dimla RD, Schultz PG. Genetic incorporation of a small, environmentally sensitive, fluorescent probe into proteins in Saccharomyces cerevisiae. Journal of the American Chemical Society. 131: 12921-3. PMID 19702307 DOI: 10.1021/ja904896s | 1 | |||
| 2009 | Gambin Y, Schug A, Lemke EA, Lavinder JJ, Ferreon AC, Magliery TJ, Onuchic JN, Deniz AA. Direct single-molecule observation of a protein living in two opposed native structures. Proceedings of the National Academy of Sciences of the United States of America. 106: 10153-8. PMID 19506258 DOI: 10.1073/pnas.0904461106 | 1 | |||
| 2009 | Ferreon AC, Gambin Y, Lemke EA, Deniz AA. Interplay of alpha-synuclein binding and conformational switching probed by single-molecule fluorescence. Proceedings of the National Academy of Sciences of the United States of America. 106: 5645-50. PMID 19293380 DOI: 10.1073/pnas.0809232106 | 1 | |||
| 2008 | Brustad EM, Lemke EA, Schultz PG, Deniz AA. A general and efficient method for the site-specific dual-labeling of proteins for single molecule fluorescence resonance energy transfer. Journal of the American Chemical Society. 130: 17664-5. PMID 19108697 DOI: 10.1021/ja807430h | 1 | |||
| 2008 | Deniz AA, Mukhopadhyay S, Lemke EA. Single-molecule biophysics: at the interface of biology, physics and chemistry. Journal of the Royal Society, Interface / the Royal Society. 5: 15-45. PMID 17519204 DOI: 10.1098/rsif.2007.1021 | 1 | |||
| 2007 | Lemke EA, Summerer D, Geierstanger BH, Brittain SM, Schultz PG. Control of protein phosphorylation with a genetically encoded photocaged amino acid Nature Chemical Biology. 3: 769-772. PMID 17965709 DOI: 10.1038/nchembio.2007.44 | 1 | |||
| 2007 | Mukhopadhyay S, Krishnan R, Lemke EA, Lindquist S, Deniz AA. A natively unfolded yeast prion monomer adopts an ensemble of collapsed and rapidly fluctuating structures. Proceedings of the National Academy of Sciences of the United States of America. 104: 2649-54. PMID 17299036 DOI: 10.1073/pnas.0611503104 | 1 | |||
| 2006 | Takamori S, Holt M, Stenius K, Lemke EA, Grønborg M, Riedel D, Urlaub H, Schenck S, Brügger B, Ringler P, Müller SA, Rammner B, Gräter F, Hub JS, De Groot BL, et al. Molecular anatomy of a trafficking organelle. Cell. 127: 831-46. PMID 17110340 DOI: 10.1016/j.cell.2006.10.030 | 1 | |||
| 2005 | Lemke EA, Klingauf J. Single synaptic vesicle tracking in individual hippocampal boutons at rest and during synaptic activity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 11034-44. PMID 16306416 DOI: 10.1523/JNEUROSCI.2971-05.2005 | 1 | |||
| 2005 | Jordan R, Lemke EA, Klingauf J. Visualization of synaptic vesicle movement in intact synaptic boutons using fluorescence fluctuation spectroscopy. Biophysical Journal. 89: 2091-102. PMID 15980175 DOI: 10.1529/biophysj.105.061663 | 1 | |||
| 2003 | Chakraborty R, Lemke EA, Cao Z, Klebba PE, van der Helm D. Identification and mutational studies of conserved amino acids in the outer membrane receptor protein, FepA, which affect transport but not binding of ferric-enterobactin in Escherichia coli. Biometals : An International Journal On the Role of Metal Ions in Biology, Biochemistry, and Medicine. 16: 507-18. PMID 12779236 DOI: 10.1023/A:1023485632520 | 1 | |||
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