| Year |
Citation |
Score |
| 2021 |
Ma L, Zhang W, Liu Z, Huang Y, Zhang Q, Tian X, Zhang C, Zhu Y. Complete genome sequence of Streptomyces sp. SCSIO 03032 isolated from Indian Ocean sediment, producing diverse bioactive natural products. Marine Genomics. 55: 100803. PMID 33517980 DOI: 10.1016/J.Margen.2020.100803 |
0.342 |
|
| 2020 |
Liu L, Li S, Sun R, Qin X, Ju J, Zhang C, Duan Y, Huang Y. Activation and Characterization of Bohemamine Biosynthetic Gene Cluster from sp. CB02009. Organic Letters. PMID 32463693 DOI: 10.1021/Acs.Orglett.0C01224 |
0.332 |
|
| 2020 |
Liu W, Jannu VG, Liu Z, Zhang Q, Jiang X, Ma L, Zhang W, Zhang C, Zhu Y. Heterologous expression of the trichostatin gene cluster and functional characterization of N-methyltransferase TsnB8. Organic & Biomolecular Chemistry. PMID 32355936 DOI: 10.1039/D0Ob00617C |
0.395 |
|
| 2020 |
Zhang C, Zhu Y, Zhang Q, Fang C, Zhang Y, Ma L, Liu Z, Zhai S, Peng J, Zhang L, Zhu W. Refactoring the Concise Biosynthetic Pathway of Cyanogramide Unveils a P450 Enzyme-catalyzed Spirooxindole Formation. Angewandte Chemie (International Ed. in English). PMID 32329169 DOI: 10.1002/Ange.202004978 |
0.427 |
|
| 2020 |
Fang C, Zhang Q, Zhu Y, Zhang L, Zhang W, Ma L, Zhang H, Zhang C. Proximicins F and G and Diproximicin A: Aminofurans from the Marine-Derived sp. SCSIO 40062 by Overexpression of PPtase Genes. Journal of Natural Products. PMID 32191465 DOI: 10.1021/Acs.Jnatprod.9B01185 |
0.341 |
|
| 2020 |
Tan B, Zhang Q, Zhu Y, Jin H, Zhang L, Chen S, Zhang C. Deciphering Biosynthetic Enzymes Leading to 4-Chloro-6-Methyl-5,7-Dihydroxyphenylglycine, a Non-Proteinogenic Amino Acid in Totopotensamides. Acs Chemical Biology. PMID 32118401 DOI: 10.1021/Acschembio.9B00997 |
0.413 |
|
| 2020 |
Manenda MS, Picard MÈ, Zhang L, Cyr N, Zhu X, Barma J, Pascal JM, Couture M, Zhang C, Shi R. Structural analyses of the group A flavin-dependent monooxygenase PieE reveal a sliding FAD cofactor conformation bridging OUT and IN conformations. The Journal of Biological Chemistry. PMID 32111738 DOI: 10.1074/Jbc.Ra119.011212 |
0.336 |
|
| 2020 |
Tan B, Chen S, Zhang Q, Chen Y, Zhu Y, Khan I, Zhang W, Zhang C. Heterologous Expression Leads to Discovery of Diversified Lobophorin Analogues and a Flexible Glycosyltransferase. Organic Letters. PMID 31971807 DOI: 10.1021/Acs.Orglett.9B04597 |
0.32 |
|
| 2020 |
Khan I, Zhang H, Liu W, Zhang L, Peng F, Chen Y, Zhang Q, Zhang G, Zhang W, Zhang C. Identification and bioactivity evaluation of secondary metabolites from Antarctic-derived Penicillium chrysogenum CCTCC M 2020019 Rsc Advances. 10: 20738-20744. DOI: 10.1039/D0Ra03529G |
0.336 |
|
| 2019 |
Liu W, Zhang W, Jin H, Zhang Q, Chen Y, Jiang X, Zhang G, Zhang L, Zhang W, She Z, Zhang C. Genome Mining of Marine-Derived sp. SCSIO 40010 Leads to Cytotoxic New Polycyclic Tetramate Macrolactams. Marine Drugs. 17. PMID 31775228 DOI: 10.3390/Md17120663 |
0.355 |
|
| 2019 |
Zheng L, Jiang X, Zhang Q, Zhu Y, Zhang H, Zhang W, Saurav K, Liu J, Zhang C. Discovery and Biosynthesis of Neoenterocins Indicate a Skeleton Rearrangement of Enterocin. Organic Letters. PMID 31657934 DOI: 10.1021/Acs.Orglett.9B03460 |
0.357 |
|
| 2019 |
Yu Z, Zhang H, Yuan C, Zhang Q, Khan I, Zhu Y, Zhang C. Characterizing Two Cytochrome P450s in Tiacumicin Biosynthesis Reveals Reaction Timing for Tailoring Modifications. Organic Letters. PMID 31508971 DOI: 10.1021/Acs.Orglett.9B03100 |
0.359 |
|
| 2019 |
Fang Z, Chen S, Zhu Y, Li J, Khan I, Zhang Q, Zhang C. A new uridine derivative and a new indole derivative from the coral-associated actinomycete sp. SCSIO 11457. Natural Product Research. 1-7. PMID 31137966 DOI: 10.1080/14786419.2019.1616729 |
0.328 |
|
| 2019 |
Huang C, Yang C, Fang Z, Zhang L, Zhang W, Zhu Y, Zhang C. Discovery of Stealthin Derivatives and Implication of the Amidotransferase FlsN3 in the Biosynthesis of Nitrogen-Containing Fluostatins. Marine Drugs. 17. PMID 30836614 DOI: 10.3390/Md17030150 |
0.383 |
|
| 2019 |
Huang C, Yang C, Zhang W, Zhu Y, Ma L, Fang Z, Zhang C. Albumycin, a new isoindolequinone from Streptomyces albus J1074 harboring the fluostatin biosynthetic gene cluster. The Journal of Antibiotics. PMID 30816348 DOI: 10.1038/S41429-019-0161-4 |
0.35 |
|
| 2018 |
Liu Z, Ma L, Zhang L, Zhang W, Zhu Y, Chen Y, Zhang W, Zhang C. Functional characterization of the halogenase SpmH and discovery of new deschloro-tryptophan dimers. Organic & Biomolecular Chemistry. PMID 30543262 DOI: 10.1039/C8Ob02775G |
0.331 |
|
| 2018 |
Huang C, Yang C, Zhu Y, Zhang W, Yuan C, Zhang C. Marine Bacterial Aromatic Polyketides From Host-Dependent Heterologous Expression and Fungal Mode of Cyclization. Frontiers in Chemistry. 6: 528. PMID 30425983 DOI: 10.3389/Fchem.2018.00528 |
0.34 |
|
| 2018 |
Huang C, Yang C, Zhang W, Zhang L, De BC, Zhu Y, Jiang X, Fang C, Zhang Q, Yuan CS, Liu HW, Zhang C. Molecular basis of dimer formation during the biosynthesis of benzofluorene-containing atypical angucyclines. Nature Communications. 9: 2088. PMID 29802272 DOI: 10.1038/S41467-018-04487-Z |
0.538 |
|
| 2018 |
Zhang H, Tian X, Pu X, Zhang Q, Zhang W, Zhang C. Tiacumicin Congeners with Improved Antibacterial Activity from a Halogenase-Inactivated Mutant. Journal of Natural Products. PMID 29676573 DOI: 10.1021/Acs.Jnatprod.7B00990 |
0.337 |
|
| 2018 |
Lin W, Das K, Degen D, Mazumder A, Duchi D, Wang D, Ebright YW, Ebright RY, Sineva E, Gigliotti M, Srivastava A, Mandal S, Jiang Y, Liu Y, Yin R, ... ... Zhang C, et al. Structural Basis of Transcription Inhibition by Fidaxomicin (Lipiarmycin A3). Molecular Cell. PMID 29606590 DOI: 10.1016/J.Molcel.2018.02.026 |
0.307 |
|
| 2018 |
Zhang W, Zhang G, Zhang L, Liu W, Jiang X, Jin H, Liu Z, Zhang H, Zhou A, Zhang C. New polycyclic tetramate macrolactams from marine-derived Streptomyces sp. SCSIO 40060 Tetrahedron. 74: 6839-6845. DOI: 10.1016/J.Tet.2018.10.007 |
0.364 |
|
| 2017 |
Chen R, Zhang Q, Tan B, Zheng L, Li H, Zhu Y, Zhang C. Genome Mining and Activation of a Silent PKS/NRPS Gene Cluster Direct the Production of Totopotensamides. Organic Letters. PMID 29019409 DOI: 10.1021/Acs.Orglett.7B02878 |
0.365 |
|
| 2017 |
Zhang Q, Li H, Yu L, Sun Y, Zhu Y, Zhu H, Zhang L, Li SM, Shen Y, Tian C, Li A, Liu HW, Zhang C. Characterization of the flavoenzyme XiaK as an N-hydroxylase and implications in indolosesquiterpene diversification. Chemical Science. 8: 5067-5077. PMID 28970893 DOI: 10.1039/C7Sc01182B |
0.57 |
|
| 2017 |
Ma L, Zhang W, Zhu Y, Zhang G, Zhang H, Zhang Q, Zhang L, Yuan C, Zhang C. Identification and characterization of a biosynthetic gene cluster for tryptophan dimers in deep sea-derived Streptomyces sp. SCSIO 03032. Applied Microbiology and Biotechnology. PMID 28620687 DOI: 10.1007/S00253-017-8375-5 |
0.391 |
|
| 2017 |
Saha S, Zhang W, Zhang G, Zhu Y, Chen Y, Liu W, Yuan C, Zhang Q, Zhang H, Zhang L, Zhang W, Zhang C. Activation and characterization of a cryptic gene cluster reveals a cyclization cascade for polycyclic tetramate macrolactams. Chemical Science. 8: 1607-1612. PMID 28451290 DOI: 10.1039/C6Sc03875A |
0.409 |
|
| 2017 |
Zhang W, Yang C, Huang C, Zhang L, Zhang H, Zhang Q, Yuan CS, Zhu Y, Zhang C. Pyrazolofluostatins A-C, Pyrazole-Fused Benzo[a]fluorenes from South China Sea-Derived Micromonospora rosaria SCSIO N160. Organic Letters. PMID 28075605 DOI: 10.1021/Acs.Orglett.6B03745 |
0.305 |
|
| 2017 |
Jiang X, Zhang Q, Zhu Y, Nie F, Wu Z, Yang C, Zhang L, Tian X, Zhang C. Isolation, structure elucidation and biosynthesis of benzo[b]fluorene nenestatin A from deep-sea derived Micromonospora echinospora SCSIO 04089 Tetrahedron. 73: 3585-3590. DOI: 10.1016/J.Tet.2017.03.054 |
0.404 |
|
| 2016 |
Zhu Y, Picard MÈ, Zhang Q, Barma J, Després XM, Mei X, Zhang L, Duvignaud JB, Couture M, Zhu W, Shi R, Zhang C. Flavoenzyme CrmK-mediated substrate recycling in caerulomycin biosynthesis. Chemical Science. 7: 4867-4874. PMID 30155134 DOI: 10.1039/C6Sc00771F |
0.387 |
|
| 2015 |
Zhu Y, Xu J, Mei X, Feng Z, Zhang L, Zhang Q, Zhang G, Zhu W, Liu J, Zhang C. Biochemical and Structural Insights into the Aminotransferase CrmG in Caerulomycin Biosynthesis. Acs Chemical Biology. PMID 26714051 DOI: 10.1021/Acschembio.5B00984 |
0.415 |
|
| 2015 |
Yang C, Huang C, Zhang W, Zhu Y, Zhang C. Heterologous Expression of Fluostatin Gene Cluster Leads to a Bioactive Heterodimer. Organic Letters. PMID 26465097 DOI: 10.1021/Acs.Orglett.5B02683 |
0.338 |
|
| 2015 |
Zhang G, Zhang W, Saha S, Zhang C. Recent Advances in Discovery, Biosynthesis and Genome Mining of Medicinally Relevant Polycyclic Tetramate Macrolactams. Current Topics in Medicinal Chemistry. PMID 26456464 DOI: 10.2174/1568026616666151012112818 |
0.41 |
|
| 2015 |
Medema MH, Kottmann R, Yilmaz P, Cummings M, Biggins JB, Blin K, de Bruijn I, Chooi YH, Claesen J, Coates RC, Cruz-Morales P, Duddela S, Düsterhus S, Edwards DJ, Fewer DP, ... ... Zhang C, et al. Minimum Information about a Biosynthetic Gene cluster. Nature Chemical Biology. 11: 625-31. PMID 26284661 DOI: 10.1038/Nchembio.1890 |
0.666 |
|
| 2015 |
Zhu Y, Zhang W, Chen Y, Yuan C, Zhang H, Zhang G, Ma L, Zhang Q, Tian X, Zhang S, Zhang C. Characterization of Heronamides Biosynthesis Reveals a Tailoring Hydroxylase and Indicates Migrated Double Bonds. Chembiochem : a European Journal of Chemical Biology. PMID 26194087 DOI: 10.1002/Cbic.201500281 |
0.334 |
|
| 2015 |
Li H, Sun Y, Zhang Q, Zhu Y, Li SM, Li A, Zhang C. Elucidating the cyclization cascades in xiamycin biosynthesis by substrate synthesis and enzyme characterizations. Organic Letters. 17: 306-9. PMID 25532029 DOI: 10.1021/Ol503399B |
0.374 |
|
| 2014 |
Fu P, Zhu Y, Mei X, Wang Y, Jia H, Zhang C, Zhu W. Acyclic congeners from Actinoalloteichus cyanogriseus provide insights into cyclic bipyridine glycoside formation. Organic Letters. 16: 4264-7. PMID 25090585 DOI: 10.1021/Ol5019757 |
0.326 |
|
| 2014 |
Zhang W, Ma L, Li S, Liu Z, Chen Y, Zhang H, Zhang G, Zhang Q, Tian X, Yuan C, Zhang S, Zhang W, Zhang C. Indimicins A-E, Bisindole Alkaloids from the Deep-Sea-Derived Streptomyces sp. SCSIO 03032. Journal of Natural Products. 77: 1887-92. PMID 25069084 DOI: 10.1021/Np500362P |
0.305 |
|
| 2014 |
Zhang G, Zhang W, Zhang Q, Shi T, Ma L, Zhu Y, Li S, Zhang H, Zhao YL, Shi R, Zhang C. Mechanistic insights into polycycle formation by reductive cyclization in ikarugamycin biosynthesis. Angewandte Chemie (International Ed. in English). 53: 4840-4. PMID 24706593 DOI: 10.1002/Anie.201402078 |
0.39 |
|
| 2014 |
Zhang W, Li S, Zhu Y, Chen Y, Chen Y, Zhang H, Zhang G, Tian X, Pan Y, Zhang S, Zhang W, Zhang C. Heronamides D-F, polyketide macrolactams from the deep-sea-derived Streptomyces sp. SCSIO 03032. Journal of Natural Products. 77: 388-91. PMID 24547685 DOI: 10.1021/Np400665A |
0.301 |
|
| 2014 |
Chen Y, Zhang W, Zhu Y, Zhang Q, Tian X, Zhang S, Zhang C. Elucidating hydroxylation and methylation steps tailoring piericidin A1 biosynthesis. Organic Letters. 16: 736-9. PMID 24409990 DOI: 10.1021/Ol4034176 |
0.343 |
|
| 2014 |
Hamel J, Murphy-Després X, Chen R, Picard M, Duvignaud J, Zhang C, Shi R. Structural studies of NenD1, an argininosuccinate lyase involved in the biosynthesis of nenemycin Acta Crystallographica Section A. 70. DOI: 10.1107/S2053273314083533 |
0.307 |
|
| 2014 |
Picard M, Barma J, Zhu Y, Després XM, Duvignaud J, Zhang C, Shi R. Structure-function studies of CrmK, an oxidase involved in Caerulomycin A biosynthesis Acta Crystallographica Section A. 70. DOI: 10.1107/S2053273314083302 |
0.302 |
|
| 2013 |
Zhu Y, Zhang Q, Li S, Lin Q, Fu P, Zhang G, Zhang H, Shi R, Zhu W, Zhang C. Insights into caerulomycin A biosynthesis: a two-component monooxygenase CrmH-catalyzed oxime formation. Journal of the American Chemical Society. 135: 18750-3. PMID 24295370 DOI: 10.1021/Ja410513G |
0.378 |
|
| 2013 |
Chen R, Zhang H, Zhang G, Li S, Zhang G, Zhu Y, Liu J, Zhang C. Characterizing amosamine biosynthesis in amicetin reveals AmiG as a reversible retaining glycosyltransferase. Journal of the American Chemical Society. 135: 12152-5. PMID 23919735 DOI: 10.1021/Ja401016E |
0.426 |
|
| 2013 |
Xiao J, Zhang Q, Zhu Y, Li S, Zhang G, Zhang H, Saurav K, Zhang C. Characterization of the sugar-O-methyltransferase LobS1 in lobophorin biosynthesis. Applied Microbiology and Biotechnology. 97: 9043-53. PMID 23868295 DOI: 10.1007/S00253-013-5083-7 |
0.378 |
|
| 2013 |
Wu ZC, Li S, Nam SJ, Liu Z, Zhang C. Nocardiamides A and B, two cyclohexapeptides from the marine-derived actinomycete Nocardiopsis sp. CNX037. Journal of Natural Products. 76: 694-701. PMID 23586970 DOI: 10.1021/Np400009A |
0.316 |
|
| 2013 |
Li S, Xiao J, Zhu Y, Zhang G, Yang C, Zhang H, Ma L, Zhang C. Dissecting glycosylation steps in lobophorin biosynthesis implies an iterative glycosyltransferase Organic Letters. 15: 1374-1377. PMID 23432710 DOI: 10.1021/Ol400342E |
0.358 |
|
| 2013 |
Zhang Q, Li S, Chen Y, Tian X, Zhang H, Zhang G, Zhu Y, Zhang S, Zhang W, Zhang C. New diketopiperazine derivatives from a deep-sea-derived Nocardiopsis alba SCSIO 03039. The Journal of Antibiotics. 66: 31-6. PMID 23093033 DOI: 10.1038/Ja.2012.88 |
0.332 |
|
| 2012 |
Zhang Q, Li H, Li S, Zhu Y, Zhang G, Zhang H, Zhang W, Shi R, Zhang C. Carboxyl formation from methyl via triple hydroxylations by XiaM in xiamycin A biosynthesis. Organic Letters. 14: 6142-5. PMID 23205935 DOI: 10.1021/Ol302782U |
0.327 |
|
| 2012 |
Zhang W, Liu Z, Li S, Lu Y, Chen Y, Zhang H, Zhang G, Zhu Y, Zhang G, Zhang W, Liu J, Zhang C. Fluostatins I-K from the South China Sea-derived micromonospora rosaria SCSIO N160. Journal of Natural Products. 75: 1937-43. PMID 23136829 DOI: 10.1021/Np300505Y |
0.301 |
|
| 2012 |
Zhang W, Liu Z, Li S, Yang T, Zhang Q, Ma L, Tian X, Zhang H, Huang C, Zhang S, Ju J, Shen Y, Zhang C. Spiroindimicins A-D: New bisindole alkaloids from a deep-sea-derived actinomycete Organic Letters. 14: 3364-3367. PMID 22694269 DOI: 10.1021/Ol301343N |
0.319 |
|
| 2012 |
Zhu Y, Fu P, Lin Q, Zhang G, Zhang H, Li S, Ju J, Zhu W, Zhang C. Identification of caerulomycin A gene cluster implicates a tailoring amidohydrolase. Organic Letters. 14: 2666-9. PMID 22591508 DOI: 10.1021/Ol300589R |
0.345 |
|
| 2012 |
Li H, Zhang Q, Li S, Zhu Y, Zhang G, Zhang H, Tian X, Zhang S, Ju J, Zhang C. Identification and characterization of xiamycin A and oxiamycin gene cluster reveals an oxidative cyclization strategy tailoring indolosesquiterpene biosynthesis. Journal of the American Chemical Society. 134: 8996-9005. PMID 22591327 DOI: 10.1021/Ja303004G |
0.36 |
|
| 2012 |
Chen Z, Zheng Z, Huang H, Song Y, Zhang X, Ma J, Wang B, Zhang C, Ju J. Penicacids A-C, three new mycophenolic acid derivatives and immunosuppressive activities from the marine-derived fungus Penicillium sp. SOF07. Bioorganic & Medicinal Chemistry Letters. 22: 3332-5. PMID 22464133 DOI: 10.1016/J.Bmcl.2012.02.106 |
0.314 |
|
| 2012 |
Ma J, Zuo D, Song Y, Wang B, Huang H, Yao Y, Li W, Zhang S, Zhang C, Ju J. Characterization of a single gene cluster responsible for methylpendolmycin and pendolmycin biosynthesis in the deep sea bacterium Marinactinospora thermotolerans. Chembiochem : a European Journal of Chemical Biology. 13: 547-52. PMID 22362652 DOI: 10.1002/Cbic.201100700 |
0.376 |
|
| 2012 |
Mo X, Ma J, Huang H, Wang B, Song Y, Zhang S, Zhang C, Ju J. Δ(11,12) double bond formation in tirandamycin biosynthesis is atypically catalyzed by TrdE, a glycoside hydrolase family enzyme. Journal of the American Chemical Society. 134: 2844-7. PMID 22280373 DOI: 10.1021/Ja206713A |
0.386 |
|
| 2012 |
Zhang G, Zhang H, Li S, Xiao J, Zhang G, Zhu Y, Niu S, Ju J, Zhang C. Characterization of the amicetin biosynthesis gene cluster from Streptomyces vinaceusdrappus NRRL 2363 implicates two alternative strategies for amide bond formation. Applied and Environmental Microbiology. 78: 2393-401. PMID 22267658 DOI: 10.1128/Aem.07185-11 |
0.376 |
|
| 2012 |
Zhu Q, Li J, Ma J, Luo M, Wang B, Huang H, Tian X, Li W, Zhang S, Zhang C, Ju J. Discovery and engineered overproduction of antimicrobial nucleoside antibiotic A201A from the deep-sea marine actinomycete Marinactinospora thermotolerans SCSIO 00652. Antimicrobial Agents and Chemotherapy. 56: 110-4. PMID 22064543 DOI: 10.1128/Aac.05278-11 |
0.374 |
|
| 2011 |
Niu S, Li S, Tian X, Hu T, Ju J, Ynag X, Zhang S, Zhang C. [Isolation and structural elucidation of secondary metabolites from marine Streptomyces sp. SCSIO 1934]. Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica. 36: 1763-8. PMID 22032140 DOI: 10.4268/Cjcmm20111315 |
0.396 |
|
| 2011 |
Li S, Tian X, Niu S, Zhang W, Chen Y, Zhang H, Yang X, Zhang W, Li W, Zhang S, Ju J, Zhang C. Pseudonocardians A-C, new diazaanthraquinone derivatives from a deap-sea actinomycete Pseudonocardia sp. SCSIO 01299. Marine Drugs. 9: 1428-39. PMID 21892356 DOI: 10.3390/Md9081428 |
0.317 |
|
| 2011 |
Niu S, Hu T, Li S, Xiao Y, Ma L, Zhang G, Zhang H, Yang X, Ju J, Zhang C. Characterization of a sugar-O-methyltransferase TiaS5 affords new Tiacumicin analogues with improved antibacterial properties and reveals substrate promiscuity. Chembiochem : a European Journal of Chemical Biology. 12: 1740-8. PMID 21633995 DOI: 10.1002/Cbic.201100129 |
0.371 |
|
| 2011 |
Mo X, Huang H, Ma J, Wang Z, Wang B, Zhang S, Zhang C, Ju J. Characterization of TrdL as a 10-hydroxy dehydrogenase and generation of new analogues from a tirandamycin biosynthetic pathway. Organic Letters. 13: 2212-5. PMID 21456513 DOI: 10.1021/Ol200447H |
0.357 |
|
| 2011 |
Mo X, Wang Z, Wang B, Ma J, Huang H, Tian X, Zhang S, Zhang C, Ju J. Cloning and characterization of the biosynthetic gene cluster of the bacterial RNA polymerase inhibitor tirandamycin from marine-derived Streptomyces sp. SCSIO1666. Biochemical and Biophysical Research Communications. 406: 341-7. PMID 21329667 DOI: 10.1016/J.Bbrc.2011.02.040 |
0.395 |
|
| 2011 |
Xiao Y, Li S, Niu S, Ma L, Zhang G, Zhang H, Zhang G, Ju J, Zhang C. Characterization of tiacumicin B biosynthetic gene cluster affording diversified tiacumicin analogues and revealing a tailoring dihalogenase. Journal of the American Chemical Society. 133: 1092-105. PMID 21186805 DOI: 10.1021/Ja109445Q |
0.399 |
|
| 2011 |
Williams GJ, Yang J, Zhang C, Thorson JS. Recombinant E. coli prototype strains for in vivo glycorandomization. Acs Chemical Biology. 6: 95-100. PMID 20886903 DOI: 10.1021/Cb100267K |
0.674 |
|
| 2008 |
Zhang C, Moretti R, Jiang J, Thorson JS. The in vitro characterization of polyene glycosyltransferases AmphDI and NysDI. Chembiochem : a European Journal of Chemical Biology. 9: 2506-14. PMID 18798210 DOI: 10.1002/Cbic.200800349 |
0.596 |
|
| 2008 |
Zhang C, Bitto E, Goff RD, Singh S, Bingman CA, Griffith BR, Albermann C, Phillips GN, Thorson JS. Biochemical and structural insights of the early glycosylation steps in calicheamicin biosynthesis. Chemistry & Biology. 15: 842-53. PMID 18721755 DOI: 10.1016/J.Chembiol.2008.06.011 |
0.745 |
|
| 2008 |
Singh S, McCoy JG, Zhang C, Bingman CA, Phillips GN, Thorson JS. Structure and mechanism of the rebeccamycin sugar 4'-O-methyltransferase RebM. The Journal of Biological Chemistry. 283: 22628-36. PMID 18502766 DOI: 10.1074/Jbc.M800503200 |
0.562 |
|
| 2008 |
Williams GJ, Goff RD, Zhang C, Thorson JS. Optimizing glycosyltransferase specificity via "hot spot" saturation mutagenesis presents a catalyst for novobiocin glycorandomization. Chemistry & Biology. 15: 393-401. PMID 18420146 DOI: 10.1016/J.Chembiol.2008.02.017 |
0.731 |
|
| 2007 |
Williams GJ, Zhang C, Thorson JS. Expanding the promiscuity of a natural-product glycosyltransferase by directed evolution. Nature Chemical Biology. 3: 657-62. PMID 17828251 DOI: 10.1038/Nchembio.2007.28 |
0.694 |
|
| 2007 |
Zhang C, Fu Q, Albermann C, Li L, Thorson JS. The in vitro characterization of the erythronolide mycarosyltransferase EryBV and its utility in macrolide diversification. Chembiochem : a European Journal of Chemical Biology. 8: 385-90. PMID 17262863 DOI: 10.1002/Cbic.200600509 |
0.729 |
|
| 2006 |
Zhang C, Albermann C, Fu X, Thorson JS. The in vitro characterization of the iterative avermectin glycosyltransferase AveBI reveals reaction reversibility and sugar nucleotide flexibility. Journal of the American Chemical Society. 128: 16420-1. PMID 17177349 DOI: 10.1021/Ja065950K |
0.754 |
|
| 2006 |
Singh S, Hager MH, Zhang C, Griffith BR, Lee MS, Hallenga K, Markley JL, Thorson JS. Structural insight into the self-sacrifice mechanism of enediyne resistance. Acs Chemical Biology. 1: 451-60. PMID 17168523 DOI: 10.1021/Cb6002898 |
0.548 |
|
| 2006 |
Zhang C, Griffith BR, Fu Q, Albermann C, Fu X, Lee IK, Li L, Thorson JS. Exploiting the reversibility of natural product glycosyltransferase-catalyzed reactions. Science (New York, N.Y.). 313: 1291-4. PMID 16946071 DOI: 10.1126/Science.1130028 |
0.756 |
|
| 2006 |
Gao Q, Zhang C, Blanchard S, Thorson JS. Deciphering indolocarbazole and enediyne aminodideoxypentose biosynthesis through comparative genomics: insights from the AT2433 biosynthetic locus. Chemistry & Biology. 13: 733-43. PMID 16873021 DOI: 10.1016/J.Chembiol.2006.05.009 |
0.59 |
|
| 2006 |
Zhang C, Albermann C, Fu X, Peters NR, Chisholm JD, Zhang G, Gilbert EJ, Wang PG, Van Vranken DL, Thorson JS. RebG- and RebM-catalyzed indolocarbazole diversification. Chembiochem : a European Journal of Chemical Biology. 7: 795-804. PMID 16575939 DOI: 10.1002/Cbic.200500504 |
0.748 |
|
| 2006 |
Borisova SA, Zhang C, Takahashi H, Zhang H, Wong AW, Thorson JS, Liu HW. Substrate specificity of the macrolide-glycosylating enzyme pair DesVII/DesVIII: opportunities, limitations, and mechanistic hypotheses. Angewandte Chemie (International Ed. in English). 45: 2748-53. PMID 16538696 DOI: 10.1002/Anie.200503195 |
0.645 |
|
| 2006 |
Zhang C, Weller RL, Thorson JS, Rajski SR. Natural product diversification using a non-natural cofactor analogue of S-adenosyl-L-methionine. Journal of the American Chemical Society. 128: 2760-1. PMID 16506729 DOI: 10.1021/Ja056231T |
0.611 |
|
| 2005 |
Fu X, Albermann C, Zhang C, Thorson JS. Diversifying vancomycin via chemoenzymatic strategies. Organic Letters. 7: 1513-5. PMID 15816740 DOI: 10.1021/Ol0501626 |
0.74 |
|
| 2003 |
Fu X, Albermann C, Jiang J, Liao J, Zhang C, Thorson JS. Antibiotic optimization via in vitro glycorandomization. Nature Biotechnology. 21: 1467-9. PMID 14608364 DOI: 10.1038/Nbt909 |
0.75 |
|
| 2003 |
Zhang CS, Podeschwa M, Block O, Altenbach HJ, Piepersberg W, Wehmeier UF. Identification of a 1-epi-valienol 7-kinase activity in the producer of acarbose, Actinoplanes sp. SE50/110. Febs Letters. 540: 53-7. PMID 12681482 DOI: 10.1016/S0014-5793(03)00222-9 |
0.316 |
|
| 2003 |
Zhang CS, Podeschwa M, Altenbach HJ, Piepersberg W, Wehmeier UF. The acarbose-biosynthetic enzyme AcbO from Actinoplanes sp. SE 50/110 is a 2-epi-5-epi-valiolone-7-phosphate 2-epimerase. Febs Letters. 540: 47-52. PMID 12681481 DOI: 10.1016/S0014-5793(03)00221-7 |
0.346 |
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| 2002 |
Zhang CS, Stratmann A, Block O, Brückner R, Podeschwa M, Altenbach HJ, Wehmeier UF, Piepersberg W. Biosynthesis of the C(7)-cyclitol moiety of acarbose in Actinoplanes species SE50/110. 7-O-phosphorylation of the initial cyclitol precursor leads to proposal of a new biosynthetic pathway. The Journal of Biological Chemistry. 277: 22853-62. PMID 11937512 DOI: 10.1074/Jbc.M202375200 |
0.41 |
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