cached image

Ian A. Wilson, D. Phil., D.Sc. - Publications

Affiliations: 
Molecular Biology Scripps Research Institute, La Jolla, La Jolla, CA, United States 
Area:
Structural biology, immunology, X-ray crystallography
Website:
http://www.scripps.edu/mb/wilson/

439 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Cho H, Gonzales-Wartz KK, Huang D, Yuan M, Peterson M, Liang J, Beutler N, Torres JL, Cong Y, Postnikova E, Bangaru S, Talana CA, Shi W, Yang ES, Zhang Y, ... ... Wilson IA, et al. Ultrapotent bispecific antibodies neutralize emerging SARS-CoV-2 variants. Biorxiv : the Preprint Server For Biology. PMID 33821267 DOI: 10.1101/2021.04.01.437942  0.36
2021 Lee CD, Watanabe Y, Wu NC, Han J, Kumar S, Pholcharee T, Seabright GE, Allen JD, Lin CW, Yang JR, Liu MT, Wu CY, Ward AB, Crispin M, Wilson IA. A cross-neutralizing antibody between HIV-1 and influenza virus. Plos Pathogens. 17: e1009407. PMID 33750987 DOI: 10.1371/journal.ppat.1009407  0.36
2021 Chen F, Tzarum N, Lin X, Giang E, Velázquez-Moctezuma R, Augestad EH, Nagy K, He L, Hernandez M, Fouch ME, Grinyó A, Chavez D, Doranz BJ, Prentoe J, Stanfield RL, ... ... Wilson IA, et al. Functional convergence of a germline-encoded neutralizing antibody response in rhesus macaques immunized with HCV envelope glycoproteins. Immunity. PMID 33675683 DOI: 10.1016/j.immuni.2021.02.013  1
2021 Liu H, Yuan M, Huang D, Bangaru S, Lee CD, Peng L, Zhu X, Nemazee D, van Gils MJ, Sanders RW, Kornau HC, Reincke SM, Pruss H, Kreye J, Wu NC, ... ... Wilson IA, et al. A combination of cross-neutralizing antibodies synergizes to prevent SARS-CoV-2 and SARS-CoV pseudovirus infection. Biorxiv : the Preprint Server For Biology. PMID 33594361 DOI: 10.1101/2021.02.11.430866  0.36
2021 Kalagiri R, Stanfield RL, Meisenhelder J, La Clair JJ, Fuhs SR, Wilson IA, Hunter T. Structural basis for differential recognition of phosphohistidine-containing peptides by 1-pHis and 3-pHis monoclonal antibodies. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33547238 DOI: 10.1073/pnas.2010644118  1
2021 Tan TJC, Yuan M, Kuzelka K, Padron GC, Beal JR, Chen X, Wang Y, Rivera-Cardona J, Zhu X, Stadtmueller BM, Brooke CB, Wilson IA, Wu NC. Sequence signatures of two IGHV3-53/3-66 public clonotypes to SARS-CoV-2 receptor binding domain. Biorxiv : the Preprint Server For Biology. PMID 33532781 DOI: 10.1101/2021.01.26.428356  0.36
2021 Koenig PA, Das H, Liu H, Kümmerer BM, Gohr FN, Jenster LM, Schiffelers LDJ, Tesfamariam YM, Uchima M, Wuerth JD, Gatterdam K, Ruetalo N, Christensen MH, Fandrey CI, Normann S, ... ... Wilson IA, et al. Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape. Science (New York, N.Y.). PMID 33436526 DOI: 10.1126/science.abe6230  0.36
2020 Lv H, Wu NC, Tsang OT, Yuan M, Perera RAPM, Leung WS, So RTY, Chan JMC, Yip GK, Chik TSH, Wang Y, Choi CYC, Lin Y, Ng WW, Zhao J, ... ... Wilson IA, et al. Cross-reactive Antibody Response between SARS-CoV-2 and SARS-CoV Infections. Cell Reports. 31: 107725. PMID 33500101 DOI: 10.1016/j.celrep.2020.107725  0.36
2020 Liu H, Wu NC, Yuan M, Bangaru S, Torres JL, Caniels TG, van Schooten J, Zhu X, Lee CD, Brouwer PJM, van Gils MJ, Sanders RW, Ward AB, Wilson IA. Cross-Neutralization of a SARS-CoV-2 Antibody to a Functionally Conserved Site Is Mediated by Avidity. Immunity. PMID 33242394 DOI: 10.1016/j.immuni.2020.10.023  0.36
2020 Yuan M, Liu H, Wu NC, Wilson IA. Recognition of the SARS-CoV-2 receptor binding domain by neutralizing antibodies. Biochemical and Biophysical Research Communications. PMID 33069360 DOI: 10.1016/j.bbrc.2020.10.012  0.36
2020 Kreye J, Reincke SM, Kornau HC, Sánchez-Sendin E, Corman VM, Liu H, Yuan M, Wu NC, Zhu X, Lee CD, Trimpert J, Höltje M, Dietert K, Stöffler L, von Wardenburg N, ... ... Wilson IA, et al. A Therapeutic Non-self-reactive SARS-CoV-2 Antibody Protects from Lung Pathology in a COVID-19 Hamster Model. Cell. PMID 33058755 DOI: 10.1016/j.cell.2020.09.049  0.36
2020 Wu NC, Yuan M, Liu H, Lee CD, Zhu X, Bangaru S, Torres JL, Caniels TG, Brouwer PJM, van Gils MJ, Sanders RW, Ward AB, Wilson IA. An Alternative Binding Mode of IGHV3-53 Antibodies to the SARS-CoV-2 Receptor Binding Domain. Cell Reports. 108274. PMID 33027617 DOI: 10.1016/j.celrep.2020.108274  0.36
2020 Wu NC, Yuan M, Bangaru S, Huang D, Zhu X, Lee CD, Turner HL, Peng L, Yang L, Nemazee D, Ward AB, Wilson IA. A natural mutation between SARS-CoV-2 and SARS-CoV determines neutralization by a cross-reactive antibody. Biorxiv : the Preprint Server For Biology. PMID 32995788 DOI: 10.1101/2020.09.21.305441  0.36
2020 Kreye J, Reincke SM, Kornau HC, Sanchez-Sendin E, Corman VM, Liu H, Yuan M, Wu NC, Zhu X, Lee CD, Trimpert J, Hoeltje M, Dietert K, Stoeffler L, von Wardenburg N, ... ... Wilson IA, et al. A SARS-CoV-2 neutralizing antibody protects from lung pathology in a COVID-19 hamster model. Biorxiv : the Preprint Server For Biology. PMID 32817952 DOI: 10.1101/2020.08.15.252320  0.36
2020 Liu H, Wu NC, Yuan M, Bangaru S, Torres JL, Caniels TG, van Schooten J, Zhu X, Lee CD, Brouwer PJM, van Gils MJ, Sanders RW, Ward AB, Wilson IA. Cross-neutralization of a SARS-CoV-2 antibody to a functionally conserved site is mediated by avidity. Biorxiv : the Preprint Server For Biology. PMID 32793906 DOI: 10.1101/2020.08.02.233536  0.36
2020 Thai E, Costa G, Weyrich A, Murugan R, Oyen D, Flores-Garcia Y, Prieto K, Bosch A, Valleriani A, Wu NC, Pholcharee T, Scally SW, Wilson IA, Wardemann H, Julien JP, et al. A high-affinity antibody against the CSP N-terminal domain lacks Plasmodium falciparum inhibitory activity. The Journal of Experimental Medicine. 217. PMID 32790871 DOI: 10.1084/Jem.20200061  0.36
2020 Tzarum N, Giang E, Kadam RU, Chen F, Nagy K, Augestad EH, Velázquez-Moctezuma R, Keck ZY, Hua Y, Stanfield RL, Dreux M, Prentoe J, Foung SKH, Bukh J, Wilson IA, et al. An alternate conformation of HCV E2 neutralizing face as an additional vaccine target. Science Advances. 6: eabb5642. PMID 32754640 DOI: 10.1126/Sciadv.Abb5642  1
2020 Wu NC, Yuan M, Liu H, Lee CD, Zhu X, Bangaru S, Torres JL, Caniels TG, Brouwer PJM, van Gils MJ, Sanders RW, Ward AB, Wilson IA. An alternative binding mode of IGHV3-53 antibodies to the SARS-CoV-2 receptor binding domain. Biorxiv : the Preprint Server For Biology. PMID 32743580 DOI: 10.1101/2020.07.26.222232  0.36
2020 Montague Z, Lv H, Otwinowski J, DeWitt WS, Isacchini G, Yip GK, Ng WW, Tsang OT, Yuan M, Liu H, Wilson IA, Peiris M, Wu NC, Nourmohammad A, Mok CKP. Dynamics of B-cell repertoires and emergence of cross-reactive responses in COVID-19 patients with different disease severity. Medrxiv : the Preprint Server For Health Sciences. PMID 32699862 DOI: 10.1101/2020.07.13.20153114  0.36
2020 Montague Z, Lv H, Otwinowski J, DeWitt WS, Isacchini G, Yip GK, Ng WW, Tsang OT, Yuan M, Liu H, Wilson IA, Peiris JSM, Wu NC, Nourmohammad A, Mok CKP. Dynamics of B-cell repertoires and emergence of cross-reactive responses in COVID-19 patients with different disease severity. Arxiv. PMID 32699813  0.36
2020 Lv H, Wu NC, Tsang OT, Yuan M, Perera RAPM, Leung WS, So RTY, Chan JMC, Yip GK, Chik TSH, Wang Y, Choi CYC, Lin Y, Ng WW, Zhao J, ... ... Wilson IA, et al. Cross-reactive Antibody Response between SARS-CoV-2 and SARS-CoV Infections. Cell Reports. 31: 107725. PMID 32684246 DOI: 10.1016/j.celrep.2020.107725  0.36
2020 Yan NL, Santos-Martins D, Rennella E, Sanchez BB, Chen JS, Kay LE, Wilson IA, Morgan GJ, Forli S, Kelly JW. Structural basis for the stabilization of amyloidogenic immunoglobulin light chains by hydantoins. Bioorganic & Medicinal Chemistry Letters. 30: 127356. PMID 32631553 DOI: 10.1016/J.Bmcl.2020.127356  0.56
2020 Wu NC, Andrews SF, Raab JE, O'Connell S, Schramm CA, Ding X, Chambers MJ, Leung K, Wang L, Zhang Y, Mascola JR, Douek DC, Ledgerwood JE, McDermott AB, Wilson IA. Convergent Evolution in Breadth of Two V6-1-Encoded Influenza Antibody Clonotypes from a Single Donor. Cell Host & Microbe. PMID 32619441 DOI: 10.1016/J.Chom.2020.06.003  0.36
2020 Wu NC, Thompson AJ, Lee JM, Su W, Arlian BM, Xie J, Lerner RA, Yen HL, Bloom JD, Wilson IA. Different genetic barriers for resistance to HA stem antibodies in influenza H3 and H1 viruses. Science (New York, N.Y.). 368: 1335-1340. PMID 32554590 DOI: 10.1126/Science.Aaz5143  0.36
2020 Stanfield RL, Berndsen ZT, Huang R, Sok D, Warner G, Torres JL, Burton DR, Ward AB, Wilson IA, Smider VV. Structural basis of broad HIV neutralization by a vaccine-induced cow antibody. Science Advances. 6: eaba0468. PMID 32518821 DOI: 10.1126/Sciadv.Aba0468  1
2020 Lv H, Wu NC, Tsang OT, Yuan M, Perera RAPM, Leung WS, So RTY, Chan JMC, Yip GK, Chik TSH, Wang Y, Choi CYC, Lin Y, Ng WW, Zhao J, ... ... Wilson IA, et al. Cross-reactive antibody response between SARS-CoV-2 and SARS-CoV infections. Biorxiv : the Preprint Server For Biology. PMID 32511317 DOI: 10.1101/2020.03.15.993097  0.36
2020 He L, Tzarum N, Lin X, Shapero B, Sou C, Mann CJ, Stano A, Zhang L, Nagy K, Giang E, Law M, Wilson IA, Zhu J. Proof of concept for rational design of hepatitis C virus E2 core nanoparticle vaccines. Science Advances. 6: eaaz6225. PMID 32494617 DOI: 10.1126/Sciadv.Aaz6225  0.36
2020 Meng B, Lan K, Xie J, Lerner RA, Wilson IA, Yang B. Inhibitory antibodies identify unique sites of therapeutic vulnerability in rhinovirus and other enteroviruses. Proceedings of the National Academy of Sciences of the United States of America. PMID 32467165 DOI: 10.1073/Pnas.1918844117  0.36
2020 Watanabe Y, Berndsen ZT, Raghwani J, Seabright GE, Allen JD, Pybus OG, McLellan JS, Wilson IA, Bowden TA, Ward AB, Crispin M. Vulnerabilities in coronavirus glycan shields despite extensive glycosylation. Nature Communications. 11: 2688. PMID 32461612 DOI: 10.1038/S41467-020-16567-0  0.36
2020 Lv H, Wu NC, Tak-Yin Tsang O, Yuan M, Perera RAPM, Leung WS, So RTY, Chun Chan JM, Yip GK, Hong Chik TS, Wang Y, Chung Choi CY, Lin Y, Ng WW, Zhao J, ... ... Wilson IA, et al. Cross-reactive antibody response between SARS-CoV-2 and SARS-CoV infections. Cell Reports. 107725. PMID 32426212 DOI: 10.1016/J.Celrep.2020.107725  0.36
2020 Perera RA, Mok CK, Tsang OT, Lv H, Ko RL, Wu NC, Yuan M, Leung WS, Chan JM, Chik TS, Choi CY, Leung K, Chan KH, Chan KC, Li KC, ... ... Wilson IA, et al. Serological assays for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), March 2020. Euro Surveillance : Bulletin Europeen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin. 25. PMID 32347204 DOI: 10.2807/1560-7917.Es.2020.25.16.2000421  0.36
2020 Yuan M, Wu NC, Zhu X, Lee CD, So RTY, Lv H, Mok CKP, Wilson IA. A highly conserved cryptic epitope in the receptor-binding domains of SARS-CoV-2 and SARS-CoV. Science (New York, N.Y.). PMID 32245784 DOI: 10.1126/Science.Abb7269  0.36
2020 Oyen D, Torres JL, Aoto PC, Flores-Garcia Y, Binter S, Pholcharee T, Carroll S, Reponen S, Wash R, Liang Q, Lemiale F, Locke E, Bradley A, King CR, Emerling D, ... ... Wilson IA, et al. Structure and mechanism of monoclonal antibody binding to the junctional epitope of Plasmodium falciparum circumsporozoite protein. Plos Pathogens. 16: e1008373. PMID 32150583 DOI: 10.1371/Journal.Ppat.1008373  0.36
2020 Wu NC, Otwinowski J, Thompson AJ, Nycholat CM, Nourmohammad A, Wilson IA. Major antigenic site B of human influenza H3N2 viruses has an evolving local fitness landscape. Nature Communications. 11: 1233. PMID 32144244 DOI: 10.1038/S41467-020-15102-5  0.36
2020 Nguyen DN, Redman RL, Horiya S, Bailey JK, Xu B, Stanfield RL, Temme JS, LaBranche CC, Wang S, Rodal AA, Montefiori DC, Wilson IA, Krauss IJ. The impact of sustained immunization regimens on the antibody response to oligomannose glycans. Acs Chemical Biology. PMID 32109354 DOI: 10.1021/Acschembio.0C00053  1
2019 Pholcharee T, Oyen D, Torres JL, Flores-Garcia Y, Martin GM, Gonzalez-Paez G, Emerling D, Volkmuth W, Locke E, King CR, Zavala F, Ward AB, Wilson IA. Diverse antibody responses to conserved structural motifs in Plasmodium falciparum circumsporozoite protein. Journal of Molecular Biology. PMID 31883801 DOI: 10.1016/J.Jmb.2019.12.029  0.36
2019 Zost SJ, Lee J, Gumina ME, Parkhouse K, Henry C, Wu NC, Lee CD, Wilson IA, Wilson PC, Bloom JD, Hensley SE. Identification of Antibodies Targeting the H3N2 Hemagglutinin Receptor Binding Site following Vaccination of Humans. Cell Reports. 29: 4460-4470.e8. PMID 31875553 DOI: 10.1016/J.Celrep.2019.11.084  0.36
2019 Wu NC, Wilson IA. Influenza Hemagglutinin Structures and Antibody Recognition. Cold Spring Harbor Perspectives in Medicine. PMID 31871236 DOI: 10.1101/Cshperspect.A038778  0.36
2019 Aoto PC, Stanfield RL, Wilson IA, Dyson HJ, Wright PE. A dynamic switch in inactive p38γ leads to an excited state on pathway to an active kinase. Biochemistry. PMID 31794659 DOI: 10.1021/Acs.Biochem.9B00932  1
2019 Adhikary R, Zimmermann J, Stanfield RL, Wilson IA, Yu W, Oda M, Romesberg FE. Structure and Dynamics of Stacking Interactions in an Antibody Binding Site. Biochemistry. PMID 31243995 DOI: 10.2210/Pdb6M87/Pdb  1
2019 Yuan M, Cottrell CA, Ozorowski G, van Gils MJ, Kumar S, Wu NC, Sarkar A, Torres JL, de Val N, Copps J, Moore JP, Sanders RW, Ward AB, Wilson IA. Conformational Plasticity in the HIV-1 Fusion Peptide Facilitates Recognition by Broadly Neutralizing Antibodies. Cell Host & Microbe. 25: 873-883.e5. PMID 31194940 DOI: 10.1016/J.Chom.2019.04.011  0.36
2019 Broszeit F, Tzarum N, Zhu X, Nemanichvili N, Eggink D, Leenders T, Li Z, Liu L, Wolfert MA, Papanikolaou A, Martínez-Romero C, Gagarinov IA, Yu W, García-Sastre A, Wennekes T, ... ... Wilson IA, et al. N-Glycolylneuraminic Acid as a Receptor for Influenza A Viruses. Cell Reports. 27: 3284-3294.e6. PMID 31189111 DOI: 10.1016/J.Celrep.2019.05.048  0.36
2019 Wu NC, Lv H, Thompson AJ, Wu DC, Ng WWS, Kadam RU, Lin CW, Nycholat CM, McBride R, Liang W, Paulson JC, Mok CKP, Wilson IA. Preventing an Antigenically Disruptive Mutation in Egg-Based H3N2 Seasonal Influenza Vaccines by Mutational Incompatibility. Cell Host & Microbe. PMID 31151913 DOI: 10.1016/J.Chom.2019.04.013  0.36
2019 Padayatti PS, Lee SC, Stanfield RL, Wen PC, Tajkhorshid E, Wilson IA, Zhang Q. Structural Insights into the Lipid A Transport Pathway in MsbA. Structure (London, England : 1993). PMID 31130486 DOI: 10.1016/J.Str.2019.04.007  1
2019 Watanabe Y, Bowden TA, Wilson IA, Crispin M. Exploitation of glycosylation in enveloped virus pathobiology. Biochimica Et Biophysica Acta. General Subjects. PMID 31121217 DOI: 10.1016/J.Bbagen.2019.05.012  0.36
2019 Hong S, Shi Y, Wu NC, Grande G, Douthit L, Wang H, Zhou W, Sharpless KB, Wilson IA, Xie J, Wu P. Bacterial glycosyltransferase-mediated cell-surface chemoenzymatic glycan modification. Nature Communications. 10: 1799. PMID 30996301 DOI: 10.1038/S41467-019-09608-W  0.36
2019 Morgan GJ, Yan NL, Mortenson DE, Rennella E, Blundon JM, Gwin RM, Lin CY, Stanfield RL, Brown SJ, Rosen H, Spicer TP, Fernandez-Vega V, Merlini G, Kay LE, Wilson IA, et al. Stabilization of amyloidogenic immunoglobulin light chains by small molecules. Proceedings of the National Academy of Sciences of the United States of America. PMID 30971495 DOI: 10.1073/Pnas.1817567116  1
2019 Chen F, Tzarum N, Wilson IA, Law M. V1-69 antiviral broadly neutralizing antibodies: genetics, structures, and relevance to rational vaccine design. Current Opinion in Virology. 34: 149-159. PMID 30884330 DOI: 10.1016/J.Coviro.2019.02.004  0.36
2019 van Dongen MJP, Kadam RU, Juraszek J, Lawson E, Brandenburg B, Schmitz F, Schepens WBG, Stoops B, van Diepen HA, Jongeneelen M, Tang C, Vermond J, van Eijgen-Obregoso Real A, Blokland S, Garg D, ... ... Wilson IA, et al. A small-molecule fusion inhibitor of influenza virus is orally active in mice. Science (New York, N.Y.). 363. PMID 30846569 DOI: 10.1126/Science.Aar6221  0.36
2019 Nguyen DN, Xu B, Stanfield RL, Bailey JK, Horiya S, Temme JS, Leon DR, LaBranche CC, Montefiori DC, Costello CE, Wilson IA, Krauss IJ. Oligomannose Glycopeptide Conjugates Elicit Antibodies Targeting the Glycan Core Rather than Its Extremities. Acs Central Science. 5: 237-249. PMID 30834312 DOI: 10.1021/Acscentsci.8B00588  1
2019 Kumar S, Sarkar A, Pugach P, Sanders RW, Moore JP, Ward AB, Wilson IA. Capturing the inherent structural dynamics of the HIV-1 envelope glycoprotein fusion peptide. Nature Communications. 10: 763. PMID 30770829 DOI: 10.1038/s41467-019-08738-5  0.36
2019 Sevy AM, Wu NC, Gilchuk IM, Parrish EH, Burger S, Yousif D, Nagel MBM, Schey KL, Wilson IA, Crowe JE, Meiler J. Multistate design of influenza antibodies improves affinity and breadth against seasonal viruses. Proceedings of the National Academy of Sciences of the United States of America. PMID 30642961 DOI: 10.2210/Pdb6D0U/Pdb  0.36
2019 Tzarum N, Giang E, Kong L, He L, Prentoe J, Augestad E, Hua Y, Castillo S, Lauer GM, Bukh J, Zhu J, Wilson IA, Law M. Genetic and structural insights into broad neutralization of hepatitis C virus by human V1-69 antibodies. Science Advances. 5: eaav1882. PMID 30613781 DOI: 10.1126/Sciadv.Aav1882  0.36
2018 Zost SJ, Wu NC, Hensley SE, Wilson IA. Immunodominance and antigenic variation of influenza virus hemagglutinin: implications for design of universal vaccine immunogens. The Journal of Infectious Diseases. PMID 30535315 DOI: 10.1093/Infdis/Jiy696  0.36
2018 Ringe RP, Pugach P, Cottrell CA, LaBranche CC, Seabright GE, Ketas TJ, Ozorowski G, Kumar S, Schorcht A, van Gils MJ, Crispin M, Montefiori DC, Wilson IA, Ward AB, Sanders RW, et al. Closing and opening holes in the glycan shield of HIV-1 envelope glycoprotein SOSIP trimers can redirect the neutralizing antibody response to the newly unmasked epitopes. Journal of Virology. PMID 30487280 DOI: 10.1128/Jvi.01656-18  0.36
2018 Laursen NS, Friesen RHE, Zhu X, Jongeneelen M, Blokland S, Vermond J, van Eijgen A, Tang C, van Diepen H, Obmolova G, van der Neut Kolfschoten M, Zuijdgeest D, Straetemans R, Hoffman RMB, Nieusma T, ... ... Wilson IA, et al. Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin. Science (New York, N.Y.). 362: 598-602. PMID 30385580 DOI: 10.1126/Science.Aaq0620  0.36
2018 Credille CV, Dick B, Morrison CN, Stokes RW, Adamek R, Wu NC, Wilson IA, Cohen SM. Structure-Activity Relationships in Metal-Binding Pharmacophores for Influenza Endonuclease. Journal of Medicinal Chemistry. PMID 30351002 DOI: 10.2210/Pdb6Dzq/Pdb  0.36
2018 Wu NC, Yamayoshi S, Ito M, Uraki R, Kawaoka Y, Wilson IA. Recurring and Adaptable Binding Motifs in Broadly Neutralizing Antibodies to Influenza Virus Are Encoded on the D3-9 Segment of the Ig Gene. Cell Host & Microbe. 24: 569-578.e4. PMID 30308159 DOI: 10.1016/J.Chom.2018.09.010  0.36
2018 Yang K, Stanfield RL, Martinez-Yamout MA, Dyson HJ, Wilson IA, Wright PE. Structural basis for cooperative regulation of KIX-mediated transcription pathways by the HTLV-1 HBZ activation domain. Proceedings of the National Academy of Sciences of the United States of America. PMID 30232260 DOI: 10.2210/Pdb6Dnq/Pdb  1
2018 Aleman F, Tzarum N, Kong L, Nagy K, Zhu J, Wilson IA, Law M. Immunogenetic and structural analysis of a class of HCV broadly neutralizing antibodies and their precursors. Proceedings of the National Academy of Sciences of the United States of America. PMID 29954862 DOI: 10.1073/Pnas.1802378115  0.36
2018 Tzarum N, Wilson IA, Law M. The Neutralizing Face of Hepatitis C Virus E2 Envelope Glycoprotein. Frontiers in Immunology. 9: 1315. PMID 29951061 DOI: 10.3389/Fimmu.2018.01315  0.36
2018 Apetri A, Crespo R, Juraszek J, Pascual G, Janson R, Zhu X, Zhang H, Keogh E, Holland T, Wadia J, Verveen H, Siregar B, Mrosek M, Taggenbrock R, Ameijde J, ... ... Wilson IA, et al. A common antigenic motif recognized by naturally occurring human V5-51/V4-1 anti-tau antibodies with distinct functionalities. Acta Neuropathologica Communications. 6: 43. PMID 29855358 DOI: 10.1186/S40478-018-0543-Z  0.36
2018 Guan W, Wu NC, Lee HHY, Li Y, Jiang W, Shen L, Wu DC, Chen R, Zhong N, Wilson IA, Peiris M, Yang Z, Mok CKP. Clinical Correlations of Transcriptional Profile in Patients Infected with Avian Influenza H7N9 Virus. The Journal of Infectious Diseases. PMID 29846612 DOI: 10.1093/Infdis/Jiy317  0.36
2018 Sarkar A, Bale S, Behrens AJ, Kumar S, Sharma SK, de Val N, Pallesen J, Irimia A, Diwanji DC, Stanfield RL, Ward AB, Crispin M, Wyatt RT, Wilson IA. Structure of a cleavage-independent HIV Env recapitulates the glycoprotein architecture of the native cleaved trimer. Nature Communications. 9: 1956. PMID 29769533 DOI: 10.1038/S41467-018-04272-Y  1
2018 Crispin M, Ward AB, Wilson IA. Structure and Immune Recognition of the HIV Glycan Shield. Annual Review of Biophysics. PMID 29595997 DOI: 10.1146/Annurev-Biophys-060414-034156  0.36
2018 Wu NC, Thompson AJ, Xie J, Lin CW, Nycholat CM, Zhu X, Lerner RA, Paulson JC, Wilson IA. A complex epistatic network limits the mutational reversibility in the influenza hemagglutinin receptor-binding site. Nature Communications. 9: 1264. PMID 29593268 DOI: 10.1038/S41467-018-03663-5  0.36
2018 Stanfield RL, Haakenson J, Deiss TC, Criscitiello MF, Wilson IA, Smider VV. The Unusual Genetics and Biochemistry of Bovine Immunoglobulins. Advances in Immunology. 137: 135-164. PMID 29455846 DOI: 10.1016/Bs.Ai.2017.12.004  1
2018 Wu NC, Wilson IA. Structural insights into the design of novel anti-influenza therapies. Nature Structural & Molecular Biology. PMID 29396418 DOI: 10.1038/S41594-018-0025-9  0.36
2017 Mortenson DE, Brighty GJ, Plate L, Bare G, Chen W, Li S, Wang H, Cravatt BF, Forli S, Powers ET, Sharpless KB, Wilson IA, Kelly JW. "Inverse Drug Discovery" Strategy To Identify Proteins That Are Targeted by Latent Electrophiles As Exemplified by Aryl Fluorosulfates. Journal of the American Chemical Society. PMID 29265822 DOI: 10.1021/Jacs.7B08366  0.56
2017 Gopal R, Jackson K, Tzarum N, Kong L, Ettenger A, Guest J, Pfaff JM, Barnes T, Honda A, Giang E, Davidson E, Wilson IA, Doranz BJ, Law M. Probing the antigenicity of hepatitis C virus envelope glycoprotein complex by high-throughput mutagenesis. Plos Pathogens. 13: e1006735. PMID 29253863 DOI: 10.1371/Journal.Ppat.1006735  0.36
2017 Wu NC, Zost SJ, Thompson AJ, Oyen D, Nycholat CM, McBride R, Paulson JC, Hensley SE, Wilson IA. A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine. Plos Pathogens. 13: e1006682. PMID 29059230 DOI: 10.1371/Journal.Ppat.1006682  0.36
2017 Kadam RU, Juraszek J, Brandenburg B, Buyck C, Schepens WBG, Kesteleyn B, Stoops B, Vreeken R, Vermond J, Goutier W, Tang C, Vogels R, Friesen RHE, Goudsmit J, van Dongen MJP, ... Wilson IA, et al. Potent peptidic fusion inhibitors of influenza virus. Science (New York, N.Y.). PMID 28971971 DOI: 10.1126/Science.Aan0516  0.36
2017 Lang S, Xie J, Zhu X, Wu NC, Lerner RA, Wilson IA. Antibody 27F3 Broadly Targets Influenza A Group 1 and 2 Hemagglutinins through a Further Variation in VH1-69 Antibody Orientation on the HA Stem. Cell Reports. 20: 2935-2943. PMID 28930686 DOI: 10.1016/J.Celrep.2017.08.084  0.36
2017 Medina-Ramírez M, Garces F, Escolano A, Skog P, de Taeye SW, Del Moral-Sanchez I, McGuire AT, Yasmeen A, Behrens AJ, Ozorowski G, van den Kerkhof TLGM, Freund NT, Dosenovic P, Hua Y, Gitlin AD, ... ... Wilson IA, et al. Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo. The Journal of Experimental Medicine. PMID 28847869 DOI: 10.1084/Jem.20161160  1
2017 Torrents de la Peña A, Julien JP, de Taeye SW, Garces F, Guttman M, Ozorowski G, Pritchard LK, Behrens AJ, Go EP, Burger JA, Schermer EE, Sliepen K, Ketas TJ, Pugach P, Yasmeen A, ... ... Wilson IA, et al. Improving the Immunogenicity of Native-like HIV-1 Envelope Trimers by Hyperstabilization. Cell Reports. 20: 1805-1817. PMID 28834745 DOI: 10.1016/J.Celrep.2017.07.077  0.36
2017 Koch K, Kalusche S, Torres JL, Stanfield RL, Danquah W, Khazanehdari K, von Briesen H, Geertsma ER, Wilson IA, Wernery U, Koch-Nolte F, Ward AB, Dietrich U. Selection of nanobodies with broad neutralizing potential against primary HIV-1 strains using soluble subtype C gp140 envelope trimers. Scientific Reports. 7: 8390. PMID 28827559 DOI: 10.1038/S41598-017-08273-7  1
2017 Wu NC, Xie J, Zheng T, Nycholat CM, Grande G, Paulson JC, Lerner RA, Wilson IA. Diversity of Functionally Permissive Sequences in the Receptor-Binding Site of Influenza Hemagglutinin. Cell Host & Microbe. 22: 247-248. PMID 28799910 DOI: 10.1016/J.Chom.2017.07.001  0.36
2017 Oyen D, Fenwick RB, Aoto PC, Stanfield RL, Wilson IA, Dyson HJ, Wright PE. Defining the Structural Basis for Allosteric Product Release from E. coli Dihydrofolate Reductase using NMR Relaxation Dispersion. Journal of the American Chemical Society. PMID 28737940 DOI: 10.1021/Jacs.7B05958  1
2017 Ozorowski G, Pallesen J, de Val N, Lyumkis D, Cottrell CA, Torres JL, Copps J, Stanfield RL, Cupo A, Pugach P, Moore JP, Wilson IA, Ward AB. Open and closed structures reveal allostery and pliability in the HIV-1 envelope spike. Nature. PMID 28700571 DOI: 10.1038/Nature23010  1
2017 de Vries RP, Tzarum N, Peng W, Thompson AJ, Ambepitiya Wickramasinghe IN, de la Pena ATT, van Breemen MJ, Bouwman KM, Zhu X, McBride R, Yu W, Sanders RW, Verheije MH, Wilson IA, Paulson JC. A single mutation in Taiwanese H6N1 influenza hemagglutinin switches binding to human-type receptors. Embo Molecular Medicine. PMID 28694323 DOI: 10.15252/Emmm.201707726  0.36
2017 Wu NC, Wilson IA. A perspective on the structural and functional constraints for immune evasion: Insights from the influenza virus. Journal of Molecular Biology. PMID 28648617 DOI: 10.1016/J.Jmb.2017.06.015  0.36
2017 Park S, Stanfield RL, Martinez-Yamout MA, Dyson HJ, Wilson IA, Wright PE. Role of the CBP catalytic core in intramolecular SUMOylation and control of histone H3 acetylation. Proceedings of the National Academy of Sciences of the United States of America. PMID 28630323 DOI: 10.1073/Pnas.1703105114  1
2017 Connelly S, Mortenson DE, Choi S, Wilson IA, Powers ET, Kelly JW, Johnson SM. Semi-quantitative models for identifying potent and selective transthyretin amyloidogenesis inhibitors. Bioorganic & Medicinal Chemistry Letters. PMID 28625364 DOI: 10.1016/J.Bmcl.2017.05.080  0.56
2017 Wu NC, Xie J, Zheng T, Nycholat CM, Grande G, Paulson JC, Lerner RA, Wilson IA. Diversity of Functionally Permissive Sequences in the Receptor-Binding Site of Influenza Hemagglutinin. Cell Host & Microbe. 21: 742-753.e8. PMID 28618270 DOI: 10.1016/J.Chom.2017.05.011  0.36
2017 de Vries RP, Peng W, Grant OC, Thompson AJ, Zhu X, Bouwman KM, de la Pena ATT, van Breemen MJ, Ambepitiya Wickramasinghe IN, de Haan CAM, Yu W, McBride R, Sanders RW, Woods RJ, Verheije MH, ... Wilson IA, et al. Three mutations switch H7N9 influenza to human-type receptor specificity. Plos Pathogens. 13: e1006390. PMID 28617868 DOI: 10.1371/Journal.Ppat.1006390  0.36
2017 Ringe RP, Ozorowski G, Rantalainen K, Struwe WB, Matthews K, Torres JL, Yasmeen A, Cottrell CA, Ketas TJ, LaBranche CC, Montefiori DC, Cupo A, Crispin M, Wilson IA, Ward AB, et al. Reducing V3 antigenicity and immunogenicity on soluble, native-like HIV-1 Env SOSIP trimers. Journal of Virology. PMID 28539451 DOI: 10.1128/Jvi.00677-17  0.36
2017 Guenaga J, Garces F, de Val N, Stanfield RL, Dubrovskaya V, Higgins B, Carrette B, Ward AB, Wilson IA, Wyatt RT. Glycine Substitution at Helix-to-Coil Transitions Facilitates the Structural Determination of a Stabilized Subtype C HIV Envelope Glycoprotein. Immunity. 46: 792-803.e3. PMID 28514686 DOI: 10.1016/J.Immuni.2017.04.014  1
2017 Wu NC, Grande G, Turner HL, Ward AB, Xie J, Lerner RA, Wilson IA. In vitro evolution of an influenza broadly neutralizing antibody is modulated by hemagglutinin receptor specificity. Nature Communications. 8: 15371. PMID 28504265 DOI: 10.1038/Ncomms15371  0.36
2017 Tzarum N, McBride R, Nycholat CM, Paulson JC, Wilson IA. Unique structural features of influenza H15 HA. Journal of Virology. PMID 28404848 DOI: 10.1128/Jvi.00046-17  0.36
2017 Tzarum N, de Vries RP, Peng W, Thompson AJ, Bouwman KM, McBride R, Yu W, Zhu X, Verheije MH, Paulson JC, Wilson IA. The 150-Loop Restricts the Host Specificity of Human H10N8 Influenza Virus. Cell Reports. 19: 235-245. PMID 28402848 DOI: 10.1016/J.Celrep.2017.03.054  0.36
2017 Irimia A, Serra AM, Sarkar A, Jacak R, Kalyuzhniy O, Sok D, Saye-Francisco KL, Schiffner T, Tingle R, Kubitz M, Adachi Y, Stanfield RL, Deller MC, Burton DR, Schief WR, ... Wilson IA, et al. Lipid interactions and angle of approach to the HIV-1 viral membrane of broadly neutralizing antibody 10E8: Insights for vaccine and therapeutic design. Plos Pathogens. 13: e1006212. PMID 28225819 DOI: 10.1371/Journal.Ppat.1006212  1
2016 Stanfield RL, Wilson IA, Smider VV. Conservation and diversity in the ultralong third heavy-chain complementarity-determining region of bovine antibodies. Science Immunology. 1: aaf7962. PMID 28783675 DOI: 10.1126/sciimmunol.aaf7962  1
2016 Peng W, de Vries RP, Grant OC, Thompson AJ, McBride R, Tsogtbaatar B, Lee PS, Razi N, Wilson IA, Woods RJ, Paulson JC. Recent H3N2 Viruses Have Evolved Specificity for Extended, Branched Human-type Receptors, Conferring Potential for Increased Avidity. Cell Host & Microbe. PMID 28017661 DOI: 10.1016/J.Chom.2016.11.004  0.36
2016 Kong L, Lee DE, Kadam RU, Liu T, Giang E, Nieusma T, Garces F, Tzarum N, Woods VL, Ward AB, Li S, Wilson IA, Law M. Structural flexibility at a major conserved antibody target on hepatitis C virus E2 antigen. Proceedings of the National Academy of Sciences of the United States of America. PMID 27791120 DOI: 10.1073/Pnas.1609780113  0.36
2016 Das N, Dewan V, Grace PM, Gunn RJ, Tamura R, Tzarum N, Watkins LR, Wilson IA, Yin H. HMGB1 Activates Proinflammatory Signaling via TLR5 Leading to Allodynia. Cell Reports. 17: 1128-1140. PMID 27760316 DOI: 10.1016/J.Celrep.2016.09.076  0.36
2016 Jardine JG, Sok D, Julien JP, Briney B, Sarkar A, Liang CH, Scherer EM, Henry Dunand CJ, Adachi Y, Diwanji D, Hsueh J, Jones M, Kalyuzhniy O, Kubitz M, Spencer S, ... ... Wilson IA, et al. Correction: Minimally Mutated HIV-1 Broadly Neutralizing Antibodies to Guide Reductionist Vaccine Design. Plos Pathogens. 12: e1005905. PMID 27627763 DOI: 10.1371/Journal.Ppat.1005905  1
2016 Steichen JM, Kulp DW, Tokatlian T, Escolano A, Dosenovic P, Stanfield RL, McCoy LE, Ozorowski G, Hu X, Kalyuzhniy O, Briney B, Schiffner T, Garces F, Freund NT, Gitlin AD, ... ... Wilson IA, et al. HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies. Immunity. PMID 27617678 DOI: 10.1016/J.Immuni.2016.08.016  1
2016 Briney B, Sok D, Jardine JG, Kulp DW, Skog P, Menis S, Jacak R, Kalyuzhniy O, de Val N, Sesterhenn F, Le KM, Ramos A, Jones M, Saye-Francisco KL, Blane TR, ... ... Wilson IA, et al. Tailored Immunogens Direct Affinity Maturation toward HIV Neutralizing Antibodies. Cell. 166: 1459-1470.e11. PMID 27610570 DOI: 10.1016/J.Cell.2016.08.005  1
2016 Stanfield RL, Wilson IA, Smider VV. Conservation and diversity in the ultralong third heavy-chain complementarity-determining region of bovine antibodies. Science Immunology. 1. PMID 27574710 DOI: 10.1126/Sciimmunol.Aaf7962  1
2016 Jardine JG, Sok D, Julien JP, Briney B, Sarkar A, Liang CH, Scherer EA, Henry Dunand CJ, Adachi Y, Diwanji D, Hsueh J, Jones M, Kalyuzhniy O, Kubitz M, Spencer S, ... ... Wilson IA, et al. Minimally Mutated HIV-1 Broadly Neutralizing Antibodies to Guide Reductionist Vaccine Design. Plos Pathogens. 12: e1005815. PMID 27560183 DOI: 10.1371/Journal.Ppat.1005815  1
2016 He L, de Val N, Morris CD, Vora N, Thinnes TC, Kong L, Azadnia P, Sok D, Zhou B, Burton DR, Wilson IA, Nemazee D, Ward AB, Zhu J. Presenting native-like trimeric HIV-1 antigens with self-assembling nanoparticles. Nature Communications. 7: 12041. PMID 27349934 DOI: 10.1038/Ncomms12041  1
2016 Kong L, He L, de Val N, Vora N, Morris CD, Azadnia P, Sok D, Zhou B, Burton DR, Ward AB, Wilson IA, Zhu J. Uncleaved prefusion-optimized gp140 trimers derived from analysis of HIV-1 envelope metastability. Nature Communications. 7: 12040. PMID 27349805 DOI: 10.1038/Ncomms12040  1
2016 MacLeod DT, Choi NM, Briney B, Garces F, Ver LS, Landais E, Murrell B, Wrin T, Kilembe W, Liang CH, Ramos A, Bian CB, Wickramasinghe L, Kong L, Eren K, ... ... Wilson IA, et al. Early Antibody Lineage Diversification and Independent Limb Maturation Lead to Broad HIV-1 Neutralization Targeting the Env High-Mannose Patch. Immunity. 44: 1215-1226. PMID 27192579 DOI: 10.1016/J.Immuni.2016.04.016  1
2016 Chen W, Dong J, Plate L, Mortenson DE, Brighty GJ, Li S, Liu Y, Galmozzi A, Lee PS, Hulce JJ, Cravatt BF, Saez E, Powers ET, Wilson IA, Sharpless KB, et al. Arylfluorosulfates Inactivate Intracellular Lipid Binding Protein(s) through Chemoselective SuFEx Reaction with a Binding-site Tyr Residue. Journal of the American Chemical Society. PMID 27191344 DOI: 10.1021/Jacs.6B02960  1
2016 Chen W, Kong L, Connelly S, Dendle JM, Liu Y, Wilson IA, Powers ET, Kelly JW. Stabilizing the CH2 Domain of an Antibody by Engineering in an Enhanced Aromatic Sequon. Acs Chemical Biology. PMID 27128252 DOI: 10.1021/Acschembio.5B01035  1
2016 Kong L, Ju B, Chen Y, He L, Ren L, Liu J, Hong K, Su B, Wang Z, Ozorowski G, Ji X, Hua Y, Chen Y, Deller MC, Hao Y, ... ... Wilson IA, et al. Key gp120 Glycans Pose Roadblocks to the Rapid Development of VRC01-Class Antibodies in an HIV-1-Infected Chinese Donor. Immunity. PMID 27067056 DOI: 10.1016/J.Immuni.2016.03.006  1
2016 Xu Q, Shoji M, Shibata S, Naito M, Sato K, Elsliger MA, Grant JC, Axelrod HL, Chiu HJ, Farr CL, Jaroszewski L, Knuth MW, Deacon AM, Godzik A, Lesley SA, ... ... Wilson IA, et al. A Distinct Type of Pilus from the Human Microbiome. Cell. PMID 27062925 DOI: 10.1016/J.Cell.2016.03.016  1
2016 Jardine JG, Kulp DW, Havenar-Daughton C, Sarkar A, Briney B, Sok D, Sesterhenn F, Ereño-Orbea J, Kalyuzhniy O, Deresa I, Hu X, Spencer S, Jones M, Georgeson E, Adachi Y, ... ... Wilson IA, et al. HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen. Science (New York, N.Y.). 351: 1458-63. PMID 27013733 DOI: 10.1126/Science.Aad9195  1
2016 Behrens AJ, Vasiljevic S, Pritchard LK, Harvey DJ, Andev RS, Krumm SA, Struwe WB, Cupo A, Kumar A, Zitzmann N, Seabright GE, Kramer HB, Spencer DI, Royle L, Lee JH, ... ... Wilson IA, et al. Composition and Antigenic Effects of Individual Glycan Sites of a Trimeric HIV-1 Envelope Glycoprotein. Cell Reports. PMID 26972002 DOI: 10.1016/J.Celrep.2016.02.058  1
2016 Thornburg NJ, Zhang H, Bangaru S, Sapparapu G, Kose N, Lampley RM, Bombardi RG, Yu Y, Graham S, Branchizio A, Yoder SM, Rock MT, Creech CB, Edwards KM, Lee D, ... ... Wilson IA, et al. H7N9 influenza virus neutralizing antibodies that possess few somatic mutations. The Journal of Clinical Investigation. PMID 26950424 DOI: 10.1172/Jci85317  1
2016 Koday MT, Nelson J, Chevalier A, Koday M, Kalinoski H, Stewart L, Carter L, Nieusma T, Lee PS, Ward AB, Wilson IA, Dagley A, Smee DF, Baker D, Fuller DH. A Computationally Designed Hemagglutinin Stem-Binding Protein Provides In Vivo Protection from Influenza Independent of a Host Immune Response. Plos Pathogens. 12: e1005409. PMID 26845438 DOI: 10.1371/Journal.Ppat.1005409  1
2016 Irimia A, Sarkar A, Stanfield RL, Wilson IA. Crystallographic Identification of Lipid as an Integral Component of the Epitope of HIV Broadly Neutralizing Antibody 4E10. Immunity. 44: 21-31. PMID 26777395 DOI: 10.1016/J.Immuni.2015.12.001  1
2015 de Taeye SW, Ozorowski G, Torrents de la Peña A, Guttman M, Julien JP, van den Kerkhof TL, Burger JA, Pritchard LK, Pugach P, Yasmeen A, Crampton J, Hu J, Bontjer I, Torres JL, Arendt H, ... ... Wilson IA, et al. Immunogenicity of Stabilized HIV-1 Envelope Trimers with Reduced Exposure of Non-neutralizing Epitopes. Cell. 163: 1702-15. PMID 26687358 DOI: 10.1016/J.Cell.2015.11.056  1
2015 Garces F, Lee JH, de Val N, Torrents de la Pena A, Kong L, Puchades C, Hua Y, Stanfield RL, Burton DR, Moore JP, Sanders RW, Ward AB, Wilson IA. Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans. Immunity. 43: 1053-63. PMID 26682982 DOI: 10.1016/J.Immuni.2015.11.007  1
2015 Bhowmik S, Chiu HP, Jones DH, Chiu HJ, Miller MD, Xu Q, Farr CL, Ridlon JM, Wells JE, Elsliger MA, Wilson IA, Hylemon PB, Lesley SA. Structure and Functional Characterization of a Bile Acid 7α Dehydratase BaiE in Secondary Bile Acid Synthesis. Proteins. PMID 26650892 DOI: 10.1002/Prot.24971  1
2015 Zhu X, Viswanathan K, Raman R, Yu W, Sasisekharan R, Wilson IA. Structural Basis for a Switch in Receptor Binding Specificity of Two H5N1 Hemagglutinin Mutants. Cell Reports. PMID 26586437 DOI: 10.1016/J.Celrep.2015.10.027  1
2015 Kong L, Torrents de la Peña A, Deller MC, Garces F, Sliepen K, Hua Y, Stanfield RL, Sanders RW, Wilson IA. Complete epitopes for vaccine design derived from a crystal structure of the broadly neutralizing antibodies PGT128 and 8ANC195 in complex with an HIV-1 Env trimer. Acta Crystallographica. Section D, Biological Crystallography. 71: 2099-108. PMID 26457433 DOI: 10.1107/S1399004715013917  1
2015 Lee JH, Leaman DP, Kim AS, Torrents de la Peña A, Sliepen K, Yasmeen A, Derking R, Ramos A, de Taeye SW, Ozorowski G, Klein F, Burton DR, Nussenzweig MC, Poignard P, Moore JP, ... ... Wilson IA, et al. Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike. Nature Communications. 6: 8167. PMID 26404402 DOI: 10.1038/Ncomms9167  1
2015 Xu Q, Mengin-Lecreulx D, Liu XW, Patin D, Farr CL, Grant JC, Chiu HJ, Jaroszewski L, Knuth MW, Godzik A, Lesley SA, Elsliger MA, Deacon AM, Wilson IA. Insights into Substrate Specificity of NlpC/P60 Cell Wall Hydrolases Containing Bacterial SH3 Domains. Mbio. 6. PMID 26374125 DOI: 10.1128/Mbio.02327-14  1
2015 Julien JP, Lee JH, Ozorowski G, Hua Y, Torrents de la Peña A, de Taeye SW, Nieusma T, Cupo A, Yasmeen A, Golabek M, Pugach P, Klasse PJ, Moore JP, Sanders RW, Ward AB, ... Wilson IA, et al. Design and structure of two HIV-1 clade C SOSIP.664 trimers that increase the arsenal of native-like Env immunogens. Proceedings of the National Academy of Sciences of the United States of America. PMID 26372963 DOI: 10.1073/Pnas.1507793112  1
2015 Ringe RP, Yasmeen A, Ozorowski G, Go EP, Pritchard LK, Guttman M, Ketas TA, Cottrell CA, Wilson IA, Sanders RW, Cupo A, Crispin M, Lee KK, Desaire H, Ward AB, et al. Influences on the design and purification of soluble, recombinant native-like HIV-1 envelope glycoprotein trimers. Journal of Virology. PMID 26311893 DOI: 10.1128/Jvi.01768-15  1
2015 Impagliazzo A, Milder F, Kuipers H, Wagner MV, Zhu X, Hoffman RM, van Meersbergen R, Huizingh J, Wanningen P, Verspuij J, de Man M, Ding Z, Apetri A, Kükrer B, Sneekes-Vriese E, ... ... Wilson IA, et al. A stable trimeric influenza hemagglutinin stem as a broadly protective immunogen. Science (New York, N.Y.). 349: 1301-6. PMID 26303961 DOI: 10.1126/Science.Aac7263  1
2015 Peng Y, Zeng W, Ye H, Han KH, Dharmarajan V, Novick S, Wilson IA, Griffin PR, Friedman JM, Lerner RA. A General Method for Insertion of Functional Proteins within Proteins via Combinatorial Selection of Permissive Junctions. Chemistry & Biology. 22: 1134-43. PMID 26278185 DOI: 10.1016/J.Chembiol.2015.07.011  0.36
2015 He L, Cheng Y, Kong L, Azadnia P, Giang E, Kim J, Wood MR, Wilson IA, Law M, Zhu J. Approaching rational epitope vaccine design for hepatitis C virus with meta-server and multivalent scaffolding. Scientific Reports. 5: 12501. PMID 26238798 DOI: 10.1038/Srep12501  1
2015 Kong L, Kadam RU, Giang E, Ruwona TB, Nieusma T, Culhane JC, Stanfield RL, Dawson PE, Wilson IA, Law M. Structure of hepatitis C virus envelope glycoprotein E1 antigenic site 314-324 in complex with antibody IGH526. Journal of Molecular Biology. PMID 26135247 DOI: 10.1016/J.Jmb.2015.06.012  1
2015 Sanders RW, van Gils MJ, Derking R, Sok D, Ketas TJ, Burger JA, Ozorowski G, Cupo A, Simonich C, Goo L, Arendt H, Kim HJ, Lee JH, Pugach P, Williams M, ... ... Wilson IA, et al. HIV-1 VACCINES. HIV-1 neutralizing antibodies induced by native-like envelope trimers. Science (New York, N.Y.). 349: aac4223. PMID 26089353 DOI: 10.1126/Science.Aac4223  1
2015 Pritchard LK, Vasiljevic S, Ozorowski G, Seabright GE, Cupo A, Ringe R, Kim HJ, Sanders RW, Doores KJ, Burton DR, Wilson IA, Ward AB, Moore JP, Crispin M. Structural Constraints Determine the Glycosylation of HIV-1 Envelope Trimers. Cell Reports. 11: 1604-13. PMID 26051934 DOI: 10.1016/J.Celrep.2015.05.017  1
2015 Baranczak A, Liu Y, Connelly S, Du WG, Greiner ER, Genereux JC, Wiseman RL, Eisele YS, Bradbury NC, Dong J, Noodleman L, Sharpless KB, Wilson IA, Encalada SE, Kelly JW. A Fluorogenic Aryl Fluorosulfate for Intraorganellar Transthyretin Imaging in Living Cells and in Caenorhabditis elegans. Journal of the American Chemical Society. 137: 7404-14. PMID 26051248 DOI: 10.1021/Jacs.5B03042  1
2015 Willis JR, Sapparapu G, Murrell S, Julien JP, Singh V, King HG, Xia Y, Pickens JA, LaBranche CC, Slaughter JC, Montefiori DC, Wilson IA, Meiler J, Crowe JE. Redesigned HIV antibodies exhibit enhanced neutralizing potency and breadth. The Journal of Clinical Investigation. 125: 2523-31. PMID 25985274 DOI: 10.1172/Jci80693  1
2015 Doores KJ, Kong L, Krumm SA, Le KM, Sok D, Laserson U, Garces F, Poignard P, Wilson IA, Burton DR. Correction for Doores et al., Two Classes of Broadly Neutralizing Antibodies within a Single Lineage Directed to the High-Mannose Patch of HIV Envelope. Journal of Virology. 89: 6525. PMID 25979983 DOI: 10.1128/Jvi.00593-15  1
2015 Kong L, Jackson KN, Wilson IA, Law M. Capitalizing on knowledge of hepatitis C virus neutralizing epitopes for rational vaccine design. Current Opinion in Virology. 11: 148-157. PMID 25932568 DOI: 10.1016/J.Coviro.2015.04.001  1
2015 Lee PS, Zhu X, Yu W, Wilson IA. Design and Structure of an Engineered Disulfide-Stabilized Influenza Virus Hemagglutinin Trimer. Journal of Virology. 89: 7417-20. PMID 25926650 DOI: 10.1128/Jvi.00808-15  1
2015 Deller MC, Johnson HA, Miller MD, Spraggon G, Elsliger MA, Wilson IA, Lesley SA. Crystal structure of a two-subunit TrkA octameric gating ring assembly. Plos One. 10: e0122512. PMID 25826626 DOI: 10.1371/Journal.Pone.0122512  1
2015 Derking R, Ozorowski G, Sliepen K, Yasmeen A, Cupo A, Torres JL, Julien JP, Lee JH, van Montfort T, de Taeye SW, Connors M, Burton DR, Wilson IA, Klasse PJ, Ward AB, et al. Comprehensive antigenic map of a cleaved soluble HIV-1 envelope trimer. Plos Pathogens. 11: e1004767. PMID 25807248 DOI: 10.1371/Journal.Ppat.1004767  1
2015 Zhang H, de Vries RP, Tzarum N, Zhu X, Yu W, McBride R, Paulson JC, Wilson IA. A human-infecting H10N8 influenza virus retains a strong preference for avian-type receptors. Cell Host & Microbe. 17: 377-84. PMID 25766296 DOI: 10.1016/J.Chom.2015.02.006  1
2015 Tzarum N, de Vries RP, Zhu X, Yu W, McBride R, Paulson JC, Wilson IA. Structure and receptor binding of the hemagglutinin from a human H6N1 influenza virus. Cell Host & Microbe. 17: 369-76. PMID 25766295 DOI: 10.1016/J.Chom.2015.02.005  1
2015 Adhikary R, Yu W, Oda M, Walker RC, Chen T, Stanfield RL, Wilson IA, Zimmermann J, Romesberg FE. Adaptive mutations alter antibody structure and dynamics during affinity maturation. Biochemistry. 54: 2085-93. PMID 25756188 DOI: 10.1021/Bi501417Q  1
2015 Lee PS, Arnell AJ, Wilson IA. Structure of the apo anti-influenza CH65 Fab. Acta Crystallographica. Section F, Structural Biology Communications. 71: 145-8. PMID 25664786 DOI: 10.1107/S2053230X14027599  1
2015 Guttman M, Cupo A, Julien JP, Sanders RW, Wilson IA, Moore JP, Lee KK. Antibody potency relates to the ability to recognize the closed, pre-fusion form of HIV Env. Nature Communications. 6: 6144. PMID 25652336 DOI: 10.1038/Ncomms7144  1
2015 Ward AB, Wilson IA. Insights into the trimeric HIV-1 envelope glycoprotein structure. Trends in Biochemical Sciences. 40: 101-7. PMID 25600289 DOI: 10.1016/J.Tibs.2014.12.006  1
2015 Pugach P, Ozorowski G, Cupo A, Ringe R, Yasmeen A, de Val N, Derking R, Kim HJ, Korzun J, Golabek M, de Los Reyes K, Ketas TJ, Julien JP, Burton DR, Wilson IA, et al. A native-like SOSIP.664 trimer based on an HIV-1 subtype B env gene. Journal of Virology. 89: 3380-95. PMID 25589637 DOI: 10.1128/Jvi.03473-14  1
2015 Kong L, Wilson IA, Kwong PD. Crystal structure of a fully glycosylated HIV-1 gp120 core reveals a stabilizing role for the glycan at Asn262. Proteins. 83: 590-6. PMID 25546301 DOI: 10.1002/Prot.24747  1
2015 Stanfield RL, De Castro C, Marzaioli AM, Wilson IA, Pantophlet R. Crystal structure of the HIV neutralizing antibody 2G12 in complex with a bacterial oligosaccharide analog of mammalian oligomannose. Glycobiology. 25: 412-9. PMID 25380763 DOI: 10.1093/Glycob/Cwu123  1
2015 Doores KJ, Kong L, Krumm SA, Le KM, Sok D, Laserson U, Garces F, Poignard P, Wilson IA, Burton DR. Two classes of broadly neutralizing antibodies within a single lineage directed to the high-mannose patch of HIV envelope. Journal of Virology. 89: 1105-18. PMID 25378488 DOI: 10.1128/Jvi.02905-14  1
2015 Lee PS, Wilson IA. Structural characterization of viral epitopes recognized by broadly cross-reactive antibodies. Current Topics in Microbiology and Immunology. 386: 323-41. PMID 25037260 DOI: 10.1007/82_2014_413  1
2015 Jiménez-Dalmaroni MJ, Radcliffe CM, Harvey DJ, Wormald MR, Verdino P, Ainge GD, Larsen DS, Painter GF, Ulevitch R, Beutler B, Rudd PM, Dwek RA, Wilson IA. Soluble human TLR2 ectodomain binds diacylglycerol from microbial lipopeptides and glycolipids. Innate Immunity. 21: 175-93. PMID 24591200 DOI: 10.1177/1753425914524077  1
2014 Stanfield RL, Wilson IA. Antibody Structure. Microbiology Spectrum. 2. PMID 26105818 DOI: 10.1128/microbiolspec.AID-0012-2013  1
2014 Xu Q, Mengin-Lecreulx D, Patin D, Grant JC, Chiu HJ, Jaroszewski L, Knuth MW, Godzik A, Lesley SA, Elsliger MA, Deacon AM, Wilson IA. Structure-guided functional characterization of DUF1460 reveals a highly specific NlpC/P60 amidase family. Structure (London, England : 1993). 22: 1799-809. PMID 25465128 DOI: 10.1016/J.Str.2014.09.018  1
2014 Sok D, van Gils MJ, Pauthner M, Julien JP, Saye-Francisco KL, Hsueh J, Briney B, Lee JH, Le KM, Lee PS, Hua Y, Seaman MS, Moore JP, Ward AB, Wilson IA, et al. Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex. Proceedings of the National Academy of Sciences of the United States of America. 111: 17624-9. PMID 25422458 DOI: 10.1073/Pnas.1415789111  1
2014 Bird GH, Irimia A, Ofek G, Kwong PD, Wilson IA, Walensky LD. Stapled HIV-1 peptides recapitulate antigenic structures and engage broadly neutralizing antibodies. Nature Structural & Molecular Biology. 21: 1058-67. PMID 25420104 DOI: 10.1038/Nsmb.2922  1
2014 Bowers PM, Verdino P, Wang Z, da Silva Correia J, Chhoa M, Macondray G, Do M, Neben TY, Horlick RA, Stanfield RL, Wilson IA, King DJ. Nucleotide insertions and deletions complement point mutations to massively expand the diversity created by somatic hypermutation of antibodies. The Journal of Biological Chemistry. 289: 33557-67. PMID 25320089 DOI: 10.1074/Jbc.M114.607176  1
2014 Chiu HJ, Grant JC, Farr CL, Jaroszewski L, Knuth MW, Miller MD, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Wilson IA. Structural analysis of arabinose-5-phosphate isomerase from Bacteroides fragilis and functional implications. Acta Crystallographica. Section D, Biological Crystallography. 70: 2640-51. PMID 25286848 DOI: 10.1107/S1399004714017052  1
2014 Garces F, Sok D, Kong L, McBride R, Kim HJ, Saye-Francisco KF, Julien JP, Hua Y, Cupo A, Moore JP, Paulson JC, Ward AB, Burton DR, Wilson IA. Structural evolution of glycan recognition by a family of potent HIV antibodies. Cell. 159: 69-79. PMID 25259921 DOI: 10.1016/J.Cell.2014.09.009  1
2014 Tan GS, Lee PS, Hoffman RM, Mazel-Sanchez B, Krammer F, Leon PE, Ward AB, Wilson IA, Palese P. Characterization of a broadly neutralizing monoclonal antibody that targets the fusion domain of group 2 influenza A virus hemagglutinin. Journal of Virology. 88: 13580-92. PMID 25210195 DOI: 10.1128/Jvi.02289-14  1
2014 Xu Q, Deller MC, Nielsen TK, Grant JC, Lesley SA, Elsliger MA, Deacon AM, Wilson IA. Structural insights into the recognition of phosphopeptide by the FHA domain of kanadaptin. Plos One. 9: e107309. PMID 25197798 DOI: 10.1371/Journal.Pone.0107309  1
2014 Kumar A, Punta M, Axelrod HL, Das D, Farr CL, Grant JC, Chiu HJ, Miller MD, Coggill PC, Klock HE, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Wilson IA. Crystal structures of three representatives of a new Pfam family PF14869 (DUF4488) suggest they function in sugar binding/uptake. Protein Science : a Publication of the Protein Society. 23: 1380-91. PMID 25044324 DOI: 10.1002/Pro.2522  1
2014 Murin CD, Julien JP, Sok D, Stanfield RL, Khayat R, Cupo A, Moore JP, Burton DR, Wilson IA, Ward AB. Structure of 2G12 Fab2 in complex with soluble and fully glycosylated HIV-1 Env by negative-stain single-particle electron microscopy. Journal of Virology. 88: 10177-88. PMID 24965454 DOI: 10.1128/Jvi.01229-14  1
2014 Lee PS, Ohshima N, Stanfield RL, Yu W, Iba Y, Okuno Y, Kurosawa Y, Wilson IA. Receptor mimicry by antibody F045-092 facilitates universal binding to the H3 subtype of influenza virus. Nature Communications. 5: 3614. PMID 24717798 DOI: 10.1038/Ncomms4614  1
2013 Kong L, Stanfield RL, Wilson IA. Molecular recognition of HIV glycans by antibodies Hiv Glycans in Infection and Immunity. 117-141. DOI: 10.1007/978-1-4614-8872-9_5  1
2012 Senutovitch N, Stanfield RL, Bhattacharyya S, Rule GS, Wilson IA, Armitage BA, Waggoner AS, Berget PB. A variable light domain fluorogen activating protein homodimerizes to activate dimethylindole red. Biochemistry. 51: 2471-85. PMID 22390683 DOI: 10.1021/Bi201422G  1
2012 Kong L, Julien JP, Calarese D, Scanlan C, Lee HK, Rudd P, Wong CH, Dwek RA, Burton DR, Wilson IA. Toward a carbohydrate-based HIV-1 vaccine Acs Symposium Series. 1102: 187-215. DOI: 10.1021/bk-2012-1102.ch007  1
2010 Huber M, Le KM, Doores KJ, Fulton Z, Stanfield RL, Wilson IA, Burton DR. Very few substitutions in a germ line antibody are required to initiate significant domain exchange. Journal of Virology. 84: 10700-7. PMID 20702640 DOI: 10.1128/Jvi.01111-10  1
2010 Pejchal R, Walker LM, Stanfield RL, Phogat SK, Koff WC, Poignard P, Burton DR, Wilson IA. Structure and function of broadly reactive antibody PG16 reveal an H3 subdomain that mediates potent neutralization of HIV-1. Proceedings of the National Academy of Sciences of the United States of America. 107: 11483-8. PMID 20534513 DOI: 10.1073/Pnas.1004600107  1
2009 Haukkala J, Laitinen I, Luoto P, Iveson P, Wilson I, Karlsen H, Cuthbertson A, Laine J, Leppänen P, Ylä-Herttula S, Knuuti J, Roivainen A. 68Ga-DOTA-RGD peptide: Biodistribution and binding into atherosclerotic plaques in mice European Journal of Nuclear Medicine and Molecular Imaging. 36: 2058-2067. PMID 19629477 DOI: 10.1007/s00259-009-1220-z  1
2009 Pejchal R, Gach JS, Brunel FM, Cardoso RM, Stanfield RL, Dawson PE, Burton DR, Zwick MB, Wilson IA. A conformational switch in human immunodeficiency virus gp41 revealed by the structures of overlapping epitopes recognized by neutralizing antibodies. Journal of Virology. 83: 8451-62. PMID 19515770 DOI: 10.1128/Jvi.00685-09  1
2009 Kwong PD, Wilson IA. HIV-1 and influenza antibodies: Seeing antigens in new ways Nature Immunology. 10: 573-578. PMID 19448659 DOI: 10.1038/Ni.1746  1
2009 An Y, Chen CY, Moyer B, Rotkiewicz P, Elsliger MA, Godzik A, Wilson IA, Balch WE. Structural and functional analysis of the globular head domain of p115 provides insight into membrane tethering. Journal of Molecular Biology. 391: 26-41. PMID 19414022 DOI: 10.1016/J.Jmb.2009.04.062  0.36
2009 Zheng M, Cooper DR, Grossoehme NE, Yu M, Hung LW, Cieslik M, Derewenda U, Lesley SA, Wilson IA, Giedroc DP, Derewenda ZS. Structure of Thermotoga maritima TM0439: implications for the mechanism of bacterial GntR transcription regulators with Zn2+-binding FCD domains. Acta Crystallographica. Section D, Biological Crystallography. 65: 356-65. PMID 19307717 DOI: 10.1107/S0907444909004727  1
2009 Ekiert DC, Bhabha G, Elsliger MA, Friesen RH, Jongeneelen M, Throsby M, Goudsmit J, Wilson IA. Antibody recognition of a highly conserved influenza virus epitope. Science (New York, N.Y.). 324: 246-51. PMID 19251591 DOI: 10.1126/Science.1171491  1
2009 Schwede T, Sali A, Honig B, Levitt M, Berman HM, Jones D, Brenner SE, Burley SK, Das R, Dokholyan NV, Dunbrack RL, Fidelis K, Fiser A, Godzik A, Huang YJ, ... ... Wilson IA, et al. Outcome of a workshop on applications of protein models in biomedical research. Structure (London, England : 1993). 17: 151-9. PMID 19217386 DOI: 10.1016/J.Str.2008.12.014  1
2009 Johnson SM, Connelly S, Wilson IA, Kelly JW. Toward optimization of the second aryl substructure common to transthyretin amyloidogenesis inhibitors using biochemical and structural studies. Journal of Medicinal Chemistry. 52: 1115-25. PMID 19191553 DOI: 10.1021/jm801347s  1
2009 Xu Q, Rife CL, Carlton D, Miller MD, Krishna SS, Elsliger MA, Abdubek P, Astakhova T, Chiu HJ, Clayton T, Duan L, Feuerhelm J, Grzechnik SK, Hale J, Han GW, ... ... Wilson IA, et al. Crystal structure of a novel archaeal AAA+ ATPase SSO1545 from Sulfolobus solfataricus. Proteins. 74: 1041-9. PMID 19089981 DOI: 10.1002/Prot.22325  1
2009 Wang W, Fridman A, Blackledge W, Connely S, Wilson IA, Pilz R, Boss GR. The phosphatidylinositol 3-kinase/Akt cassette regulates purine nucleotide synthesis Journal of Biological Chemistry. 284: 3521-3528. PMID 19068483 DOI: 10.1074/Jbc.M806707200  1
2009 Xu Q, McMullan D, Abdubek P, Astakhova T, Carlton D, Chen C, Chiu HJ, Clayton T, Das D, Deller MC, Duan L, Elsliger MA, Feuerhelm J, Hale J, Han GW, ... ... Wilson IA, et al. A structural basis for the regulatory inactivation of DnaA. Journal of Molecular Biology. 385: 368-80. PMID 19000695 DOI: 10.1016/J.Jmb.2008.10.059  1
2009 Laitinen I, Marjamäki P, Någren K, Laine VJO, Wilson I, Leppänen P, Ylä-Herttuala S, Roivainen A, Knuuti J. Uptake of inflammatory cell marker [11C]PK11195 into mouse atherosclerotic plaques European Journal of Nuclear Medicine and Molecular Imaging. 36: 73-80. PMID 18712383 DOI: 10.1007/s00259-008-0919-6  1
2008 Zajonc DM, Striegl H, Dascher CC, Wilson IA. The crystal structure of avian CD1 reveals a smaller, more primordial antigen-binding pocket compared to mammalian CD1 Proceedings of the National Academy of Sciences of the United States of America. 105: 17925-17930. PMID 19004781 DOI: 10.1073/Pnas.0809814105  1
2008 Jaroszewski L, Slabinski L, Wooley J, Deacon AM, Lesley SA, Wilson IA, Godzik A. Genome pool strategy for structural coverage of protein families. Structure (London, England : 1993). 16: 1659-67. PMID 19000818 DOI: 10.1016/J.Str.2008.08.018  1
2008 Shore DA, Issafras H, Landais E, Teyton L, Wilson IA. The Crystal Structure of CD8 in Complex with YTS156.7.7 Fab and Interaction with Other CD8 Antibodies Define the Binding Mode of CD8 αβ to MHC Class I Journal of Molecular Biology. 384: 1190-1202. PMID 18929574 DOI: 10.1016/J.Jmb.2008.09.069  1
2008 Han BW, Herrin BR, Cooper MD, Wilson IA. Antigen recognition by variable lymphocyte receptors. Science (New York, N.Y.). 321: 1834-7. PMID 18818359 DOI: 10.1126/Science.1162484  1
2008 Johnson SM, Connelly S, Wilson IA, Kelly JW. Toward optimization of the linker substructure common to transthyretin amyloidogenesis inhibitors using biochemical and structural studies. Journal of Medicinal Chemistry. 51: 6348-58. PMID 18811132 DOI: 10.1021/Jm800435S  1
2008 Yu X, Tsibane T, McGraw PA, House FS, Keefer CJ, Hicar MD, Tumpey TM, Pappas C, Perrone LA, Martinez O, Stevens J, Wilson IA, Aguilar PV, Altschuler EL, Basler CF, et al. Neutralizing antibodies derived from the B cells of 1918 influenza pandemic survivors. Nature. 455: 532-6. PMID 18716625 DOI: 10.1038/Nature07231  1
2008 Xu X, Zhu X, Dwek RA, Stevens J, Wilson IA. Structural characterization of the 1918 influenza virus H1N1 neuraminidase. Journal of Virology. 82: 10493-501. PMID 18715929 DOI: 10.1128/Jvi.00959-08  1
2008 Verdino P, Aldag C, Hilvert D, Wilson IA. Closely related antibody receptors exploit fundamentally different strategies for steroid recognition Proceedings of the National Academy of Sciences of the United States of America. 105: 11725-11730. PMID 18689687 DOI: 10.1073/Pnas.0801783105  1
2008 DeMartino JK, Hwang I, Connelly S, Wilson IA, Boger DL. Asymmetric synthesis of inhibitors of glycinamide ribonucleotide transformylase. Journal of Medicinal Chemistry. 51: 5441-8. PMID 18686942 DOI: 10.1021/Jm800555H  1
2008 Stevens J, Blixt O, Chen LM, Donis RO, Paulson JC, Wilson IA. Recent Avian H5N1 Viruses Exhibit Increased Propensity for Acquiring Human Receptor Specificity Journal of Molecular Biology. 381: 1382-1394. PMID 18672252 DOI: 10.1016/J.Jmb.2008.04.016  1
2008 Zhu X, Xu X, Wilson IA. Structure determination of the 1918 H1N1 neuraminidase from a crystal with lattice-translocation defects Acta Crystallographica Section D: Biological Crystallography. 64: 843-850. PMID 18645233 DOI: 10.1107/S0907444908016648  1
2008 Dhillon AK, Stanfield RL, Gorny MK, Williams C, Zolla-Pazner S, Wilson IA. Structure determination of an anti-HIV-1 Fab 447-52D-peptide complex from an epitaxially twinned data set Acta Crystallographica Section D: Biological Crystallography. 64: 792-802. PMID 18566514 DOI: 10.1107/S0907444908013978  1
2008 Relloso M, Cheng TY, Im JS, Parisini E, Roura-Mir C, DeBono C, Zajonc DM, Murga LF, Ondrechen MJ, Wilson IA, Porcelli SA, Moody DB. pH-dependent interdomain tethers of CD1b regulate its antigen capture. Immunity. 28: 774-86. PMID 18538591 DOI: 10.1016/J.Immuni.2008.04.017  1
2008 Astronomo RD, Lee HK, Scanlan CN, Pantophlet R, Huang CY, Wilson IA, Blixt O, Dwek RA, Wong CH, Burton DR. A glycoconjugate antigen based on the recognition motif of a broadly neutralizing human immunodeficiency virus antibody, 2G12, is immunogenic but elicits antibodies unable to bind to the self glycans of gp120. Journal of Virology. 82: 6359-68. PMID 18434393 DOI: 10.1128/Jvi.00293-08  1
2008 Wei CJ, Xu L, Kong WP, Shi W, Canis K, Stevens J, Yang ZY, Dell A, Haslam SM, Wilson IA, Nabel GJ. Comparative efficacy of neutralizing antibodies elicited by recombinant hemagglutinin proteins from avian H5N1 influenza virus. Journal of Virology. 82: 6200-8. PMID 18417563 DOI: 10.1128/Jvi.00187-08  1
2008 Debler EW, Müller R, Hilvert D, Wilson IA. Conformational isomerism can limit antibody catalysis. The Journal of Biological Chemistry. 283: 16554-60. PMID 18417480 DOI: 10.1074/Jbc.M710256200  1
2008 Kozbial P, Xu Q, Chiu HJ, McMullan D, Krishna SS, Miller MD, Abdubek P, Acosta C, Astakhova T, Axelrod HL, Carlton D, Clayton T, Deller M, Duan L, Elias Y, ... ... Wilson IA, et al. Crystal structures of MW1337R and lin2004: representatives of a novel protein family that adopt a four-helical bundle fold. Proteins. 71: 1589-96. PMID 18324683 DOI: 10.1002/Prot.22020  1
2008 Debler EW, Kaufmann GF, Meijler MM, Heine A, Mee JM, Pljevaljcic G, Di Bilio AJ, Schultz PG, Millar DP, Janda KD, Wilson IA, Gray HB, Lerner RA. Deeply inverted electron-hole recombination in a luminescent antibody-stilbene complex. Science (New York, N.Y.). 319: 1232-5. PMID 18309081 DOI: 10.1126/Science.1153445  1
2008 Zajonc DM, Savage PB, Bendelac A, Wilson IA, Teyton L. Crystal Structures of Mouse CD1d-iGb3 Complex and its Cognate Vα14 T Cell Receptor Suggest a Model for Dual Recognition of Foreign and Self Glycolipids Journal of Molecular Biology. 377: 1104-1116. PMID 18295796 DOI: 10.1016/J.Jmb.2008.01.061  1
2008 Xu Q, Kozbial P, McMullan D, Krishna SS, Brittain SM, Ficarro SB, DiDonato M, Miller MD, Abdubek P, Axelrod HL, Chiu HJ, Clayton T, Duan L, Elsliger MA, Feuerhelm J, ... ... Wilson IA, et al. Crystal structure of an ADP-ribosylated protein with a cytidine deaminase-like fold, but unknown function (TM1506), from Thermotoga maritima at 2.70 A resolution. Proteins. 71: 1546-52. PMID 18275082 DOI: 10.1002/Prot.21992  1
2008 Axelrod HL, McMullan D, Krishna SS, Miller MD, Elsliger MA, Abdubek P, Ambing E, Astakhova T, Carlton D, Chiu HJ, Clayton T, Duan L, Feuerhelm J, Grzechnik SK, Hale J, ... ... Wilson IA, et al. Crystal structure of AICAR transformylase IMP cyclohydrolase (TM1249) from Thermotoga maritima at 1.88 A resolution. Proteins. 71: 1042-9. PMID 18260100 DOI: 10.1002/Prot.21967  1
2008 Gräslund S, Nordlund P, Weigelt J, Hallberg BM, Bray J, Gileadi O, Knapp S, Oppermann U, Arrowsmith C, Hui R, Ming J, dhe-Paganon S, ... ... Wilson IA, et al. Protein production and purification. Nature Methods. 5: 135-46. PMID 18235434 DOI: 10.1038/Nmeth.F.202  1
2008 Menendez A, Calarese DA, Stanfield RL, Chow KC, Scanlan CN, Kunert R, Katinger H, Burton DR, Wilson IA, Scott JK. A peptide inhibitor of HIV-1 neutralizing antibody 2G12 is not a structural mimic of the natural carbohydrate epitope on gp120. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 1380-92. PMID 18198210 DOI: 10.1096/Fj.07-8983Com  1
2008 Burley SK, Joachimiak A, Montelione GT, Wilson IA. Contributions to the NIH-NIGMS Protein Structure Initiative from the PSI Production Centers Structure. 16: 5-11. PMID 18184575 DOI: 10.1016/J.Str.2007.12.002  1
2008 Johnson SM, Connelly S, Wilson IA, Kelly JW. Biochemical and structural evaluation of highly selective 2-arylbenzoxazole-based transthyretin amyloidogenesis inhibitors. Journal of Medicinal Chemistry. 51: 260-70. PMID 18095641 DOI: 10.1021/Jm0708735  1
2008 Bell CH, Pantophlet R, Schiefner A, Cavacini LA, Stanfield RL, Burton DR, Wilson IA. Structure of antibody F425-B4e8 in complex with a V3 peptide reveals a new binding mode for HIV-1 neutralization. Journal of Molecular Biology. 375: 969-78. PMID 18068724 DOI: 10.1016/J.Jmb.2007.11.013  1
2007 Slabinski L, Jaroszewski L, Rodrigues APC, Rychlewski L, Wilson IA, Lesley SA, Godzik A. The challenge of protein structure determination - Lessons from structural genomics Protein Science. 16: 2472-2482. PMID 17962404 DOI: 10.1110/Ps.073037907  1
2007 Slabinski L, Jaroszewski L, Rychlewski L, Wilson IA, Lesley SA, Godzik A. XtalPred: A web server for prediction of protein crystallizability Bioinformatics. 23: 3403-3405. PMID 17921170 DOI: 10.1093/Bioinformatics/Btm477  1
2007 Huang CC, Lam SN, Acharya P, Tang M, Xiang SH, Hussan SS, Stanfield RL, Robinson J, Sodroski J, Wilson IA, Wyatt R, Bewley CA, Kwong PD. Structures of the CCR5 N terminus and of a tyrosine-sulfated antibody with HIV-1 gp120 and CD4. Science (New York, N.Y.). 317: 1930-4. PMID 17901336 DOI: 10.1126/Science.1145373  1
2007 Burton DR, Wilson IA. Immunology: Square-dancing antibodies Science. 317: 1507-1508. PMID 17872431 DOI: 10.1126/Science.1148905  1
2007 Stoll R, Lee BM, Debler EW, Laity JH, Wilson IA, Dyson HJ, Wright PE. Structure of the Wilms tumor suppressor protein zinc finger domain bound to DNA. Journal of Molecular Biology. 372: 1227-45. PMID 17716689 DOI: 10.1016/J.Jmb.2007.07.017  1
2007 Huang S, Romanchuk G, Pattridge K, Lesley SA, Wilson IA, Matthews RG, Ludwig M. Reactivation of methionine synthase from Thermotoga maritima (TM0268) requires the downstream gene product TM0269. Protein Science : a Publication of the Protein Society. 16: 1588-95. PMID 17656578 DOI: 10.1110/Ps.072936307  1
2007 Krishna SS, Tautz L, Xu Q, McMullan D, Miller MD, Abdubek P, Ambing E, Astakhova T, Axelrod HL, Carlton D, Chiu HJ, Clayton T, DiDonato M, Duan L, Elsliger MA, ... ... Wilson IA, et al. Crystal structure of NMA1982 from Neisseria meningitidis at 1.5 angstroms resolution provides a structural scaffold for nonclassical, eukaryotic-like phosphatases. Proteins. 69: 415-21. PMID 17636569 DOI: 10.1002/Prot.21314  1
2007 Zajonc DM, Wilson IA. Architecture of CD1 proteins Current Topics in Microbiology and Immunology. 314: 27-50. PMID 17593656 DOI: 10.1007/978-3-540-69511-0_2  1
2007 Zubieta C, Krishna SS, McMullan D, Miller MD, Abdubek P, Agarwalla S, Ambing E, Astakhova T, Axelrod HL, Carlton D, Chiu HJ, Clayton T, Deller M, DiDonato M, Duan L, ... ... Wilson IA, et al. Crystal structure of homoserine O-succinyltransferase from Bacillus cereus at 2.4 A resolution. Proteins. 68: 999-1005. PMID 17546672 DOI: 10.1002/Prot.21208  1
2007 Sanguineti S, Centeno Crowley JM, Lodeiro Merlo MF, Cerutti ML, Wilson IA, Goldbaum FA, Stanfield RL, de Prat-Gay G. Specific Recognition of a DNA Immunogen by its Elicited Antibody Journal of Molecular Biology. 370: 183-195. PMID 17512945 DOI: 10.1016/J.Jmb.2007.04.046  1
2007 Debler EW, Kaufmann GF, Kirchdoerfer RN, Mee JM, Janda KD, Wilson IA. Crystal structures of a quorum-quenching antibody. Journal of Molecular Biology. 368: 1392-402. PMID 17400249 DOI: 10.1016/J.Jmb.2007.02.081  1
2007 Xu L, Chong Y, Hwang I, D'Onofrio A, Amore K, Beardsley GP, Li C, Olson AJ, Boger DL, Wilson IA. Structure-based design, synthesis, evaluation, and crystal structures of transition state analogue inhibitors of inosine monophosphate cyclohydrolase. The Journal of Biological Chemistry. 282: 13033-46. PMID 17324932 DOI: 10.1074/Jbc.M607293200  1
2007 Nelson JD, Brunel FM, Jensen R, Crooks ET, Cardoso RM, Wang M, Hessell A, Wilson IA, Binley JM, Dawson PE, Burton DR, Zwick MB. An affinity-enhanced neutralizing antibody against the membrane-proximal external region of human immunodeficiency virus type 1 gp41 recognizes an epitope between those of 2F5 and 4E10. Journal of Virology. 81: 4033-43. PMID 17287272 DOI: 10.1128/Jvi.02588-06  1
2007 Stanfield RL, Dooley H, Verdino P, Flajnik MF, Wilson IA. Maturation of shark single-domain (IgNAR) antibodies: evidence for induced-fit binding. Journal of Molecular Biology. 367: 358-72. PMID 17258766 DOI: 10.1016/J.Jmb.2006.12.045  1
2007 Müller R, Debler EW, Steinmann M, Seebeck FP, Wilson IA, Hilvert D. Bifunctional catalysis of proton transfer at an antibody active site. Journal of the American Chemical Society. 129: 460-1. PMID 17226987 DOI: 10.1021/Ja066578B  1
2007 Frank RA, Långström B, Antoni G, Montalto MC, Agdeppa ED, Mendizabal M, Wilson IA, Vanderheyden JL. The imaging continuum: Bench to biomarkers to diagnostics Journal of Labelled Compounds and Radiopharmaceuticals. 50: 746-769. DOI: 10.1002/jlcr.1444  1
2006 Tian F, Debler EW, Millar DP, Deniz AA, Wilson IA, Schultz PG. The effects of antibodies on stilbene excited-state energetics. Angewandte Chemie (International Ed. in English). 45: 7763-5. PMID 17089439 DOI: 10.1002/Anie.200602720  1
2006 Stevens J, Blixt O, Paulson JC, Wilson IA. Glycan microarray technologies: Tools to survey host specificity of influenza viruses Nature Reviews Microbiology. 4: 857-864. PMID 17013397 DOI: 10.1038/Nrmicro1530  1
2006 Cooper ZD, Narasimhan D, Sunahara RK, Mierzejewski P, Jutkiewicz EM, Larsen NA, Wilson IA, Landry DW, Woods JH. Rapid and robust protection against cocaine-induced lethality in rats by the bacterial cocaine esterase. Molecular Pharmacology. 70: 1885-91. PMID 16968810 DOI: 10.1124/Mol.106.025999  1
2006 DiDonato M, Krishna SS, Schwarzenbacher R, McMullan D, Agarwalla S, Brittain SM, Miller MD, Abdubek P, Ambing E, Axelrod HL, Canaves JM, Chiu HJ, Deacon AM, Duan L, Elsliger MA, ... ... Wilson IA, et al. Crystal structure of 2-phosphosulfolactate phosphatase (ComB) from Clostridium acetobutylicum at 2.6 A resolution reveals a new fold with a novel active site. Proteins. 65: 771-6. PMID 16927339 DOI: 10.1002/Prot.20978  1
2006 Kinjo Y, Tupin E, Wu D, Fujio M, Garcia-Navarro R, Benhnia MR, Zajonc DM, Ben-Menachem G, Ainge GD, Painter GF, Khurana A, Hoebe K, Behar SM, Beutler B, Wilson IA, et al. Natural killer T cells recognize diacylglycerol antigens from pathogenic bacteria. Nature Immunology. 7: 978-86. PMID 16921381 DOI: 10.1038/Ni1380  1
2006 Mathews II, Krishna SS, Schwarzenbacher R, McMullan D, Jaroszewski L, Miller MD, Abdubek P, Agarwalla S, Ambing E, Axelrod HL, Canaves JM, Carlton D, Chiu HJ, Clayton T, DiDonato M, ... ... Wilson IA, et al. Crystal structure of phosphoribosylformyl-glycinamidine synthase II, PurS subunit (TM1244) from Thermotoga maritima at 1.90 A resolution. Proteins. 65: 249-54. PMID 16865708 DOI: 10.1002/Prot.21024  1
2006 Schwarzenbacher R, McMullan D, Krishna SS, Xu Q, Miller MD, Canaves JM, Elsliger MA, Floyd R, Grzechnik SK, Jaroszewski L, Klock HE, Koesema E, Kovarik JS, Kreusch A, Kuhn P, ... ... Wilson IA, et al. Crystal structure of a glycerate kinase (TM1585) from Thermotoga maritima at 2.70 A resolution reveals a new fold. Proteins. 65: 243-8. PMID 16865707 DOI: 10.1002/Prot.21058  1
2006 Jiang Z, Georgel P, Li C, Choe J, Crozat K, Rutschmann S, Du X, Bigby T, Mudd S, Sovath S, Wilson IA, Olson A, Beutler B. Details of Toll-like receptor:adapter interaction revealed by germ-line mutagenesis. Proceedings of the National Academy of Sciences of the United States of America. 103: 10961-6. PMID 16832055 DOI: 10.1073/Pnas.0603804103  1
2006 Cheng TY, Relloso M, Van Rhijn I, Young DC, Besra GS, Briken V, Zajonc DM, Wilson IA, Porcelli S, Moody DB. Role of lipid trimming and CD1 groove size in cellular antigen presentation. The Embo Journal. 25: 2989-99. PMID 16794581 DOI: 10.1038/Sj.Emboj.7601185  1
2006 Xu Q, Schwarzenbacher R, Krishna SS, McMullan D, Agarwalla S, Quijano K, Abdubek P, Ambing E, Axelrod H, Biorac T, Canaves JM, Chiu HJ, Elsliger MA, Grittini C, Grzechnik SK, ... ... Wilson IA, et al. Crystal structure of acireductone dioxygenase (ARD) from Mus musculus at 2.06 angstrom resolution. Proteins. 64: 808-13. PMID 16783794 DOI: 10.1002/Prot.20947  1
2006 Han GW, Sri Krishna S, Schwarzenbacher R, McMullan D, Ginalski K, Elsliger MA, Brittain SM, Abdubek P, Agarwalla S, Ambing E, Astakhova T, Axelrod H, Canaves JM, Chiu HJ, DiDonato M, ... ... Wilson IA, et al. Crystal structure of the ApbE protein (TM1553) from Thermotoga maritima at 1.58 A resolution. Proteins. 64: 1083-90. PMID 16779835 DOI: 10.1002/Prot.20950  1
2006 Stanfield RL, Gorny MK, Zolla-Pazner S, Wilson IA. Crystal structures of human immunodeficiency virus type 1 (HIV-1) neutralizing antibody 2219 in complex with three different V3 peptides reveal a new binding mode for HIV-1 cross-reactivity. Journal of Virology. 80: 6093-105. PMID 16731948 DOI: 10.1128/Jvi.00205-06  1
2006 DeMartino JK, Hwang I, Xu L, Wilson IA, Boger DL. Discovery of a potent, nonpolyglutamatable inhibitor of glycinamide ribonucleotide transformylase. Journal of Medicinal Chemistry. 49: 2998-3002. PMID 16686541 DOI: 10.1021/Jm0601147  1
2006 Johnson MA, Peti W, Herrmann T, Wilson IA, Wüthrich K. Solution structure of Asl1650, an acyl carrier protein from Anabaena sp. PCC 7120 with a variant phosphopantetheinylation-site sequence. Protein Science : a Publication of the Protein Society. 15: 1030-41. PMID 16597827 DOI: 10.1110/Ps.051964606  1
2006 Rudolph MG, Stanfield RL, Wilson IA. How TCRs bind MHCs, peptides, and coreceptors. Annual Review of Immunology. 24: 419-66. PMID 16551255 DOI: 10.1146/Annurev.Immunol.23.021704.115658  1
2006 Mathews II, Krishna SS, Schwarzenbacher R, McMullan D, Abdubek P, Ambing E, Canaves JM, Chiu HJ, Deacon AM, DiDonato M, Elsliger MA, Godzik A, Grittini C, Grzechnik SK, Hale J, ... ... Wilson IA, et al. Crystal structure of phosphoribosylformylglycinamidine synthase II (smPurL) from Thermotoga maritima at 2.15 A resolution. Proteins. 63: 1106-11. PMID 16544324 DOI: 10.1002/Prot.20650  1
2006 Jin KK, Krishna SS, Schwarzenbacher R, McMullan D, Abdubek P, Agarwalla S, Ambing E, Axelrod H, Canaves JM, Chiu HJ, Deacon AM, DiDonato M, Elsliger MA, Feuerhelm J, Godzik A, ... ... Wilson IA, et al. Crystal structure of TM1367 from Thermotoga maritima at 1.90 A resolution reveals an atypical member of the cyclophilin (peptidylprolyl isomerase) fold. Proteins. 63: 1112-8. PMID 16544291 DOI: 10.1002/Prot.20894  1
2006 Stevens J, Blixt O, Tumpey TM, Taubenberger JK, Paulson JC, Wilson IA. Structure and receptor specificity of the hemagglutinin from an H5N1 influenza virus Science. 312: 404-410. PMID 16543414 DOI: 10.1126/Science.1124513  1
2006 Wu D, Zajonc DM, Fujio M, Sullivan BA, Kinjo Y, Kronenberg M, Wilson IA, Wong CH. Design of natural killer T cell activators: structure and function of a microbial glycosphingolipid bound to mouse CD1d. Proceedings of the National Academy of Sciences of the United States of America. 103: 3972-7. PMID 16537470 DOI: 10.1073/Pnas.0600285103  1
2006 Zhu X, Wentworth P, Kyle RA, Lerner RA, Wilson IA. Cofactor-containing antibodies: crystal structure of the original yellow antibody. Proceedings of the National Academy of Sciences of the United States of America. 103: 3581-5. PMID 16537445 DOI: 10.1073/Pnas.0600251103  1
2006 Shore DA, Teyton L, Dwek RA, Rudd PM, Wilson IA. Crystal Structure of the TCR Co-receptor CD8αα in Complex with Monoclonal Antibody YTS 105.18 Fab Fragment at 2.88 Å Resolution Journal of Molecular Biology. 358: 347-354. PMID 16530222 DOI: 10.1016/J.Jmb.2006.02.016  1
2006 Stanfield RL, Zemla A, Wilson IA, Rupp B. Antibody elbow angles are influenced by their light chain class. Journal of Molecular Biology. 357: 1566-74. PMID 16497332 DOI: 10.1016/J.Jmb.2006.01.023  1
2006 Stauber DJ, Debler EW, Horton PA, Smith KA, Wilson IA. Crystal structure of the IL-2 signaling complex: paradigm for a heterotrimeric cytokine receptor. Proceedings of the National Academy of Sciences of the United States of America. 103: 2788-93. PMID 16477002 DOI: 10.1073/Pnas.0511161103  1
2006 Zhu X, Dickerson TJ, Rogers CJ, Kaufmann GF, Mee JM, McKenzie KM, Janda KD, Wilson IA. Complete reaction cycle of a cocaine catalytic antibody at atomic resolution. Structure (London, England : 1993). 14: 205-16. PMID 16472740 DOI: 10.1016/J.Str.2005.10.014  1
2006 Brunel FM, Zwick MB, Cardoso RM, Nelson JD, Wilson IA, Burton DR, Dawson PE. Structure-function analysis of the epitope for 4E10, a broadly neutralizing human immunodeficiency virus type 1 antibody. Journal of Virology. 80: 1680-7. PMID 16439525 DOI: 10.1128/Jvi.80.4.1680-1687.2006  1
2006 DiDonato M, Krishna SS, Schwarzenbacher R, McMullan D, Jaroszewski L, Miller MD, Abdubek P, Agarwalla S, Ambing E, Axelrod H, Biorac T, Chiu HJ, Deacon AM, Elsliger MA, Feuerhelm J, ... ... Wilson IA, et al. Crystal structure of a single-stranded DNA-binding protein (TM0604) from Thermotoga maritima at 2.60 A resolution. Proteins. 63: 256-60. PMID 16435371 DOI: 10.1002/Prot.20841  1
2006 Stevens J, Blixt O, Glaser L, Taubenberger JK, Palese P, Paulson JC, Wilson IA. Glycan microarray analysis of the hemagglutinins from modern and pandemic influenza viruses reveals different receptor specificities. Journal of Molecular Biology. 355: 1143-55. PMID 16343533 DOI: 10.1016/J.Jmb.2005.11.002  1
2006 Xu Q, Schwarzenbacher R, McMullan D, Abdubek P, Agarwalla S, Ambing E, Axelrod H, Biorac T, Canaves JM, Chiu HJ, Deacon AM, DiDonato M, Elsliger MA, Godzik A, Grittini C, ... ... Wilson IA, et al. Crystal structure of virulence factor CJ0248 from Campylobacter jejuni at 2.25 A resolution reveals a new fold. Proteins. 62: 292-6. PMID 16287129 DOI: 10.1002/Prot.20611  1
2005 Shore DA, Wilson IA, Dwek RA, Rudd PM. Glycosylation and the function of the T cell co-receptor CD8 Advances in Experimental Medicine and Biology. 564: 71-84. PMID 16400808 DOI: 10.1007/0-387-25515-X_12  1
2005 Zajonc DM, Maricic I, Wu D, Halder R, Roy K, Wong CH, Kumar V, Wilson IA. Structural basis for CD1d presentation of a sulfatide derived from myelin and its implications for autoimmunity. The Journal of Experimental Medicine. 202: 1517-26. PMID 16314439 DOI: 10.1084/Jem.20051625  1
2005 Huang CC, Tang M, Zhang MY, Majeed S, Montabana E, Stanfield RL, Dimitrov DS, Korber B, Sodroski J, Wilson IA, Wyatt R, Kwong PD. Structural biology: Structure of a V3-containing HIV-1 gp120 core Science. 310: 1025-1028. PMID 16284180 DOI: 10.1126/Science.1118398  1
2005 Peti W, Page R, Moy K, O'Neil-Johnson M, Wilson IA, Stevens RC, Wüthrich K. Towards miniaturization of a structural genomics pipeline using micro-expression and microcoil NMR. Journal of Structural and Functional Genomics. 6: 259-67. PMID 16283429 DOI: 10.1007/S10969-005-9000-X  1
2005 Klock HE, Schwarzenbacher R, Xu Q, McMullan D, Abdubek P, Ambing E, Axelrod H, Biorac T, Canaves JM, Chiu HJ, Deacon AM, DiDonato M, Elsliger MA, Godzik A, Grittini C, ... ... Wilson IA, et al. Crystal structure of a conserved hypothetical protein (gi: 13879369) from Mouse at 1.90 A resolution reveals a new fold. Proteins. 61: 1132-6. PMID 16224779 DOI: 10.1002/Prot.20610  1
2005 Burton DR, Stanfield RL, Wilson IA. Antibody vs. HIV in a clash of evolutionary titans. Proceedings of the National Academy of Sciences of the United States of America. 102: 14943-8. PMID 16219699 DOI: 10.1073/Pnas.0505126102  1
2005 Almeida MS, Herrmann T, Peti W, Wilson IA, Wüthrich K. NMR structure of the conserved hypothetical protein TM0487 from Thermotoga maritima: implications for 216 homologous DUF59 proteins. Protein Science : a Publication of the Protein Society. 14: 2880-6. PMID 16199668 DOI: 10.1110/Ps.051755805  1
2005 Calarese DA, Lee HK, Huang CY, Best MD, Astronomo RD, Stanfield RL, Katinger H, Burton DR, Wong CH, Wilson IA. Dissection of the carbohydrate specificity of the broadly neutralizing anti-HIV-1 antibody 2G12. Proceedings of the National Academy of Sciences of the United States of America. 102: 13372-7. PMID 16174734 DOI: 10.1073/Pnas.0505763102  1
2005 Jaroszewski L, Schwarzenbacher R, McMullan D, Abdubek P, Agarwalla S, Ambing E, Axelrod H, Biorac T, Canaves JM, Chiu HJ, Deacon AM, DiDonato M, Elsliger MA, Godzik A, Grittini C, ... ... Wilson IA, et al. Crystal structure of Hsp33 chaperone (TM1394) from Thermotoga maritima at 2.20 A resolution. Proteins. 61: 669-73. PMID 16167343 DOI: 10.1002/Prot.20542  1
2005 Rife C, Schwarzenbacher R, McMullan D, Abdubek P, Ambing E, Axelrod H, Biorac T, Canaves JM, Chiu HJ, Deacon AM, DiDonato M, Elsliger MA, Godzik A, Grittini C, Grzechnik SK, ... ... Wilson IA, et al. Crystal structure of a putative modulator of DNA gyrase (pmbA) from Thermotoga maritima at 1.95 A resolution reveals a new fold. Proteins. 61: 444-8. PMID 16104019 DOI: 10.1002/Prot.20468  1
2005 Rife C, Schwarzenbacher R, McMullan D, Abdubek P, Ambing E, Axelrod H, Biorac T, Canaves JM, Chiu HJ, Deacon AM, DiDonato M, Elsliger MA, Godzik A, Grittini C, Grzechnik SK, ... ... Wilson IA, et al. Crystal structure of the global regulatory protein CsrA from Pseudomonas putida at 2.05 A resolution reveals a new fold. Proteins. 61: 449-53. PMID 16104018 DOI: 10.1002/Prot.20502  1
2005 Glaser L, Stevens J, Zamarin D, Wilson IA, García-Sastre A, Tumpey TM, Basler CF, Taubenberger JK, Palese P. A single amino acid substitution in 1918 influenza virus hemagglutinin changes receptor binding specificity. Journal of Virology. 79: 11533-6. PMID 16103207 DOI: 10.1128/Jvi.79.17.11533-11536.2005  1
2005 Zajonc DM, Cantu C, Mattner J, Zhou D, Savage PB, Bendelac A, Wilson IA, Teyton L. Structure and function of a potent agonist for the semi-invariant natural killer T cell receptor. Nature Immunology. 6: 810-8. PMID 16007091 DOI: 10.1038/Ni1224  1
2005 Han GW, Schwarzenbacher R, McMullan D, Abdubek P, Ambing E, Axelrod H, Biorac T, Canaves JM, Chiu HJ, Dai X, Deacon AM, DiDonato M, Elsliger MA, Godzik A, Grittini C, ... ... Wilson IA, et al. Crystal structure of an Apo mRNA decapping enzyme (DcpS) from Mouse at 1.83 A resolution. Proteins. 60: 797-802. PMID 16001405 DOI: 10.1002/Prot.20467  1
2005 Choe J, Kelker MS, Wilson IA. Crystal structure of human toll-like receptor 3 (TLR3) ectodomain. Science (New York, N.Y.). 309: 581-5. PMID 15961631 DOI: 10.1126/Science.1115253  1
2005 Van Rhijn I, Zajonc DM, Wilson IA, Moody DB. T-cell activation by lipopeptide antigens. Current Opinion in Immunology. 17: 222-9. PMID 15886110 DOI: 10.1016/J.Coi.2005.04.006  1
2005 Moody DB, Zajonc DM, Wilson IA. Anatomy of CD1-lipid antigen complexes. Nature Reviews. Immunology. 5: 387-99. PMID 15864273 DOI: 10.1038/Nri1605  1
2005 Cheng H, Hwang I, Chong Y, Tavassoli A, Webb ME, Zhang Y, Wilson IA, Benkovic SJ, Boger DL. Synthesis and biological evaluation of N-[4-[5-(2,4-diamino-6-oxo-1,6-dihydropyrimidin-5-yl)-2-(2,2,2-trifluoroacetyl)pentyl]benzoyl]-L-glutamic acid as a potential inhibitor of GAR Tfase and the de novo purine biosynthetic pathway. Bioorganic & Medicinal Chemistry. 13: 3593-9. PMID 15848772 DOI: 10.1016/J.Bmc.2004.11.049  1
2005 Chong Y, Hwang I, Tavassoli A, Zhang Y, Wilson IA, Benkovic SJ, Boger DL. Synthesis and biological evaluation of alpha- and gamma-carboxamide derivatives of 10-CF3CO-DDACTHF. Bioorganic & Medicinal Chemistry. 13: 3587-92. PMID 15848771 DOI: 10.1016/J.Bmc.2004.11.050  1
2005 Cheng H, Chong Y, Hwang I, Tavassoli A, Zhang Y, Wilson IA, Benkovic SJ, Boger DL. Design, synthesis, and biological evaluation of 10-methanesulfonyl-DDACTHF, 10-methanesulfonyl-5-DACTHF, and 10-methylthio-DDACTHF as potent inhibitors of GAR Tfase and the de novo purine biosynthetic pathway. Bioorganic & Medicinal Chemistry. 13: 3577-85. PMID 15848770 DOI: 10.1016/J.Bmc.2004.12.004  1
2005 Wilson IA, Stanfield RL. MHC restriction: slip-sliding away. Nature Immunology. 6: 434-5. PMID 15843798 DOI: 10.1038/Ni0505-434  1
2005 Wiseman RL, Johnson SM, Kelker MS, Foss T, Wilson IA, Kelly JW. Kinetic stabilization of an oligomeric protein by a single ligand binding event. Journal of the American Chemical Society. 127: 5540-51. PMID 15826192 DOI: 10.1021/Ja042929F  1
2005 Mathews I, Schwarzenbacher R, McMullan D, Abdubek P, Ambing E, Axelrod H, Biorac T, Canaves JM, Chiu HJ, Deacon AM, DiDonato M, Elsliger MA, Godzik A, Grittini C, Grzechnik SK, ... ... Wilson IA, et al. Crystal structure of S-adenosylmethionine:tRNA ribosyltransferase-isomerase (QueA) from Thermotoga maritima at 2.0 A resolution reveals a new fold. Proteins. 59: 869-74. PMID 15822125 DOI: 10.1002/Prot.20419  1
2005 Levin I, Miller MD, Schwarzenbacher R, McMullan D, Abdubek P, Ambing E, Biorac T, Cambell J, Canaves JM, Chiu HJ, Deacon AM, DiDonato M, Elsliger MA, Godzik A, Grittini C, ... ... Wilson IA, et al. Crystal structure of an indigoidine synthase A (IndA)-like protein (TM1464) from Thermotoga maritima at 1.90 A resolution reveals a new fold. Proteins. 59: 864-8. PMID 15822122 DOI: 10.1002/Prot.20420  1
2005 Debler EW, Ito S, Seebeck FP, Heine A, Hilvert D, Wilson IA. Structural origins of efficient proton abstraction from carbon by a catalytic antibody. Proceedings of the National Academy of Sciences of the United States of America. 102: 4984-9. PMID 15788533 DOI: 10.1073/Pnas.0409207102  1
2005 Foss TR, Kelker MS, Wiseman RL, Wilson IA, Kelly JW. Kinetic stabilization of the native state by protein engineering: implications for inhibition of transthyretin amyloidogenesis. Journal of Molecular Biology. 347: 841-54. PMID 15769474 DOI: 10.1016/J.Jmb.2005.01.050  1
2005 Zajonc DM, Crispin MD, Bowden TA, Young DC, Cheng TY, Hu J, Costello CE, Rudd PM, Dwek RA, Miller MJ, Brenner MB, Moody DB, Wilson IA. Molecular mechanism of lipopeptide presentation by CD1a. Immunity. 22: 209-19. PMID 15723809 DOI: 10.1016/J.Immuni.2004.12.009  1
2005 Cardoso RM, Zwick MB, Stanfield RL, Kunert R, Binley JM, Katinger H, Burton DR, Wilson IA. Broadly neutralizing anti-HIV antibody 4E10 recognizes a helical conformation of a highly conserved fusion-associated motif in gp41. Immunity. 22: 163-73. PMID 15723805 DOI: 10.1016/J.Immuni.2004.12.011  1
2005 Page R, Peti W, Wilson IA, Stevens RC, Wüthrich K. NMR screening and crystal quality of bacterially expressed prokaryotic and eukaryotic proteins in a structural genomics pipeline. Proceedings of the National Academy of Sciences of the United States of America. 102: 1901-5. PMID 15677718 DOI: 10.1073/Pnas.0408490102  1
2005 Hava DL, Brigl M, van den Elzen P, Zajonc DM, Wilson IA, Brenner MB. CD1 assembly and the formation of CD1-antigen complexes. Current Opinion in Immunology. 17: 88-94. PMID 15653316 DOI: 10.1016/J.Coi.2004.12.003  1
2005 Xu Q, Schwarzenbacher R, McMullan D, Abdubek P, Ambing E, Biorac T, Canaves JM, Chiu HJ, Dai X, Deacon AM, DiDonato M, Elsliger MA, Godzik A, Grittini C, Grzechnik SK, ... ... Wilson IA, et al. Crystal structure of a formiminotetrahydrofolate cyclodeaminase (TM1560) from Thermotoga maritima at 2.80 A resolution reveals a new fold. Proteins. 58: 976-81. PMID 15651027 DOI: 10.1002/Prot.20364  1
2004 Li C, Xu L, Wolan DW, Wilson IA, Olson AJ. Virtual screening of human 5-aminoimidazole-4-carboxamide ribonucleotide transformylase against the NCI diversity set by use of AutoDock to identify novel nonfolate inhibitors. Journal of Medicinal Chemistry. 47: 6681-90. PMID 15615517 DOI: 10.1021/Jm049504O  1
2004 Blixt O, Head S, Mondala T, Scanlan C, Huflejt ME, Alvarez R, Bryan MC, Fazio F, Calarese D, Stevens J, Razi N, Stevens DJ, Skehel JJ, van Die I, Burton DR, ... Wilson IA, et al. Printed covalent glycan array for ligand profiling of diverse glycan binding proteins. Proceedings of the National Academy of Sciences of the United States of America. 101: 17033-8. PMID 15563589 DOI: 10.1073/Pnas.0407902101  1
2004 Kelker MS, Debler EW, Wilson IA. Crystal structure of mouse triggering receptor expressed on myeloid cells 1 (TREM-1) at 1.76 A. Journal of Molecular Biology. 344: 1175-81. PMID 15561137 DOI: 10.1016/J.Jmb.2004.10.009  1
2004 Canaves JM, Page R, Wilson IA, Stevens RC. Protein biophysical properties that correlate with crystallization success in Thermotoga maritima: maximum clustering strategy for structural genomics. Journal of Molecular Biology. 344: 977-91. PMID 15544807 DOI: 10.1016/J.Jmb.2004.09.076  1
2004 Zhu X, Tanaka F, Hu Y, Heine A, Fuller R, Zhong G, Olson AJ, Lerner RA, Barbas CF, Wilson IA. The origin of enantioselectivity in aldolase antibodies: crystal structure, site-directed mutagenesis, and computational analysis. Journal of Molecular Biology. 343: 1269-80. PMID 15491612 DOI: 10.1016/J.Jmb.2004.08.102  1
2004 Wang X, Matteson J, An Y, Moyer B, Yoo JS, Bannykh S, Wilson IA, Riordan JR, Balch WE. COPII-dependent export of cystic fibrosis transmembrane conductance regulator from the ER uses a di-acidic exit code. The Journal of Cell Biology. 167: 65-74. PMID 15479737 DOI: 10.1083/Jcb.200401035  1
2004 Xu L, Li C, Olson AJ, Wilson IA. Crystal structure of avian aminoimidazole-4-carboxamide ribonucleotide transformylase in complex with a novel non-folate inhibitor identified by virtual ligand screening Journal of Biological Chemistry. 279: 50555-50565. PMID 15355974 DOI: 10.1074/Jbc.M406801200  1
2004 Kelker MS, Foss TR, Peti W, Teyton L, Kelly JW, Wüthrich K, Wilson IA. Crystal structure of human triggering receptor expressed on myeloid cells 1 (TREM-1) at 1.47 A. Journal of Molecular Biology. 342: 1237-48. PMID 15351648 DOI: 10.1016/j.jmb.2004.07.089  1
2004 Miller MD, Schwarzenbacher R, von Delft F, Abdubek P, Ambing E, Biorac T, Brinen LS, Canaves JM, Cambell J, Chiu HJ, Dai X, Deacon AM, DiDonato M, Elsliger MA, Eshagi S, ... ... Wilson IA, et al. Crystal structure of a tandem cystathionine-beta-synthase (CBS) domain protein (TM0935) from Thermotoga maritima at 1.87 A resolution. Proteins. 57: 213-7. PMID 15326606 DOI: 10.1002/Prot.20024  1
2004 Stanfield RL, Dooley H, Flajnik MF, Wilson IA. Crystal structure of a shark single-domain antibody V region in complex with lysozyme. Science (New York, N.Y.). 305: 1770-3. PMID 15319492 DOI: 10.1126/Science.1101148  1
2004 Bryan MC, Fazio F, Lee HK, Huang CY, Chang A, Best MD, Calarese DA, Blixt O, Paulson JC, Burton D, Wilson IA, Wong CH. Covalent display of oligosaccharide arrays in microtiter plates. Journal of the American Chemical Society. 126: 8640-1. PMID 15250702 DOI: 10.1021/Ja048433F  1
2004 Levin I, Schwarzenbacher R, McMullan D, Abdubek P, Ambing E, Biorac T, Cambell J, Canaves JM, Chiu HJ, Dai X, Deacon AM, DiDonato M, Elsliger MA, Godzik A, Grittini C, ... ... Wilson IA, et al. Crystal structure of a putative NADPH-dependent oxidoreductase (GI: 18204011) from mouse at 2.10 A resolution. Proteins. 56: 629-33. PMID 15229897 DOI: 10.1002/Prot.20163  1
2004 McMullan D, Schwarzenbacher R, Jaroszewski L, von Delft F, Klock HE, Vincent J, Quijano K, Abdubek P, Ambing E, Biorac T, Brinen LS, Canaves JM, Dai X, Deacon AM, DiDonato M, ... ... Wilson IA, et al. Crystal structure of a novel Thermotoga maritima enzyme (TM1112) from the cupin family at 1.83 A resolution. Proteins. 56: 615-8. PMID 15229894 DOI: 10.1002/Prot.20139  1
2004 Jaroszewski L, Schwarzenbacher R, von Delft F, McMullan D, Brinen LS, Canaves JM, Dai X, Deacon AM, DiDonato M, Elsliger MA, Eshagi S, Floyd R, Godzik A, Grittini C, Grzechnik SK, ... ... Wilson IA, et al. Crystal structure of a novel manganese-containing cupin (TM1459) from Thermotoga maritima at 1.65 A resolution. Proteins. 56: 611-4. PMID 15229893 DOI: 10.1002/Prot.20130  1
2004 Bakolitsa C, Schwarzenbacher R, McMullan D, Brinen LS, Canaves JM, Dai X, Deacon AM, Elsliger MA, Eshagi S, Floyd R, Godzik A, Grittini C, Grzechnik SK, Jaroszewski L, Karlak C, ... ... Wilson IA, et al. Crystal structure of an orphan protein (TM0875) from Thermotoga maritima at 2.00-A resolution reveals a new fold. Proteins. 56: 607-10. PMID 15229892 DOI: 10.1002/Prot.20138  1
2004 Spraggon G, Schwarzenbacher R, Kreusch A, McMullan D, Brinen LS, Canaves JM, Dai X, Deacon AM, Elsliger MA, Eshagi S, Floyd R, Godzik A, Grittini C, Grzechnik SK, Jaroszewski L, ... ... Wilson IA, et al. Crystal structure of a methionine aminopeptidase (TM1478) from Thermotoga maritima at 1.9 A resolution. Proteins. 56: 396-400. PMID 15211524 DOI: 10.1002/Prot.20084  1
2004 Schwarzenbacher R, von Delft F, Jaroszewski L, Abdubek P, Ambing E, Biorac T, Brinen LS, Canaves JM, Cambell J, Chiu HJ, Dai X, Deacon AM, DiDonato M, Elsliger MA, Eshagi S, ... ... Wilson IA, et al. Crystal structure of a putative oxalate decarboxylase (TM1287) from Thermotoga maritima at 1.95 A resolution. Proteins. 56: 392-5. PMID 15211523 DOI: 10.1002/Prot.20016  1
2004 Heine A, Canaves JM, von Delft F, Brinen LS, Dai X, Deacon AM, Elsliger MA, Eshaghi S, Floyd R, Godzik A, Grittini C, Grzechnik SK, Guda C, Jaroszewski L, Karlak C, ... ... Wilson IA, et al. Crystal structure of O-acetylserine sulfhydrylase (TM0665) from Thermotoga maritima at 1.8 A resolution. Proteins. 56: 387-91. PMID 15211522 DOI: 10.1002/Prot.20003  1
2004 Larsen NA, de Prada P, Deng SX, Mittal A, Braskett M, Zhu X, Wilson IA, Landry DW. Crystallographic and biochemical analysis of cocaine-degrading antibody 15A10. Biochemistry. 43: 8067-76. PMID 15209502 DOI: 10.1021/Bi049495L  1
2004 Xu Q, Schwarzenbacher R, McMullan D, von Delft F, Brinen LS, Canaves JM, Dai X, Deacon AM, Elsliger MA, Eshagi S, Floyd R, Godzik A, Grittini C, Grzechnik SK, Jaroszewski L, ... ... Wilson IA, et al. Crystal structure of a ribose-5-phosphate isomerase RpiB (TM1080) from Thermotoga maritima at 1.90 A resolution. Proteins. 56: 171-5. PMID 15162497 DOI: 10.1002/Prot.20129  1
2004 Santelli E, Schwarzenbacher R, McMullan D, Biorac T, Brinen LS, Canaves JM, Cambell J, Dai X, Deacon AM, Elsliger MA, Eshagi S, Floyd R, Godzik A, Grittini C, Grzechnik SK, ... ... Wilson IA, et al. Crystal structure of a glycerophosphodiester phosphodiesterase (GDPD) from Thermotoga maritima (TM1621) at 1.60 A resolution. Proteins. 56: 167-70. PMID 15162496 DOI: 10.1002/Prot.20120  1
2004 Crispin MD, Ritchie GE, Critchley AJ, Morgan BP, Wilson IA, Dwek RA, Sim RB, Rudd PM. Monoglucosylated glycans in the secreted human complement component C3: implications for protein biosynthesis and structure. Febs Letters. 566: 270-4. PMID 15147907 DOI: 10.1016/J.Febslet.2004.04.045  1
2004 Spraggon G, Schwarzenbacher R, Kreusch A, Lee CC, Abdubek P, Ambing E, Biorac T, Brinen LS, Canaves JM, Cambell J, Chiu HJ, Dai X, Deacon AM, DiDonato M, Elsliger MA, ... ... Wilson IA, et al. Crystal structure of an Udp-n-acetylmuramate-alanine ligase MurC (TM0231) from Thermotoga maritima at 2.3 A resolution. Proteins. 55: 1078-81. PMID 15146505 DOI: 10.1002/Prot.20034  1
2004 Schwarzenbacher R, Jaroszewski L, von Delft F, Abdubek P, Ambing E, Biorac T, Brinen LS, Canaves JM, Cambell J, Chiu HJ, Dai X, Deacon AM, DiDonato M, Elsliger MA, Eshagi S, ... ... Wilson IA, et al. Crystal structure of a type II quinolic acid phosphoribosyltransferase (TM1645) from Thermotoga maritima at 2.50 A resolution. Proteins. 55: 768-71. PMID 15103640 DOI: 10.1002/Prot.20029  1
2004 Schwarzenbacher R, Jaroszewski L, von Delft F, Abdubek P, Ambing E, Biorac T, Brinen LS, Canaves JM, Cambell J, Chiu HJ, Dai X, Deacon AM, DiDonato M, Elsliger MA, Eshagi S, ... ... Wilson IA, et al. Crystal structure of an aspartate aminotransferase (TM1255) from Thermotoga maritima at 1.90 A resolution. Proteins. 55: 759-63. PMID 15103638 DOI: 10.1002/Prot.10646  1
2004 Schwarzenbacher R, Jaroszewski L, von Delft F, Abdubek P, Ambing E, Biorac T, Brinen LS, Canaves JM, Cambell J, Chiu HJ, Dai X, Deacon AM, DiDonato M, Elsliger MA, Eshagi S, ... ... Wilson IA, et al. Crystal structure of a phosphoribosylaminoimidazole mutase PurE (TM0446) from Thermotoga maritima at 1.77-A resolution. Proteins. 55: 474-8. PMID 15048837 DOI: 10.1002/Prot.20023  1
2004 Rudolph MG, Wingren C, Crowley MP, Chien YH, Wilson IA. Combined pseudo-merohedral twinning, non-crystallographic symmetry and pseudo-translation in a monoclinic crystal form of the gammadelta T-cell ligand T10. Acta Crystallographica. Section D, Biological Crystallography. 60: 656-64. PMID 15039553 DOI: 10.1107/S0907444904002239  0.36
2004 Schwarzenbacher R, von Delft F, Abdubek P, Ambing E, Biorac T, Brinen LS, Canaves JM, Cambell J, Chiu HJ, Dai X, Deacon AM, DiDonato M, Elsliger MA, Eshagi S, Floyd R, ... ... Wilson IA, et al. Crystal structure of a putative PII-like signaling protein (TM0021) from Thermotoga maritima at 2.5 A resolution. Proteins. 54: 810-3. PMID 14997579 DOI: 10.1002/Prot.10647  1
2004 Erlandsen H, Canaves JM, Elsliger MA, von Delft F, Brinen LS, Dai X, Deacon AM, Floyd R, Godzik A, Grittini C, Grzechnik SK, Jaroszewski L, Klock HE, Koesema E, Kovarik JS, ... ... Wilson IA, et al. Crystal structure of an HEPN domain protein (TM0613) from Thermotoga maritima at 1.75 A resolution. Proteins. 54: 806-9. PMID 14997578 DOI: 10.1002/Prot.10631  1
2004 Schwarzenbacher R, Deacon AM, Jaroszewski L, Brinen LS, Canaves JM, Dai X, Elsliger MA, Floyd R, Godzik A, Grittini C, Grzechnik SK, Klock HE, Koesema E, Kovarik JS, Kreusch A, ... ... Wilson IA, et al. Crystal structure of a putative glutamine amido transferase (TM1158) from Thermotoga maritima at 1.7 A resolution. Proteins. 54: 801-5. PMID 14997577 DOI: 10.1002/Prot.10614  1
2004 Zwick MB, Komori HK, Stanfield RL, Church S, Wang M, Parren PW, Kunert R, Katinger H, Wilson IA, Burton DR. The long third complementarity-determining region of the heavy chain is important in the activity of the broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2F5. Journal of Virology. 78: 3155-61. PMID 14990736 DOI: 10.1128/Jvi.78.6.3155-3161.2004  1
2004 Kuhmann SE, Pugach P, Kunstman KJ, Taylor J, Stanfield RL, Snyder A, Strizki JM, Riley J, Baroudy BM, Wilson IA, Korber BT, Wolinsky SM, Moore JP. Genetic and phenotypic analyses of human immunodeficiency virus type 1 escape from a small-molecule CCR5 inhibitor. Journal of Virology. 78: 2790-807. PMID 14990699 DOI: 10.1128/Jvi.78.6.2790-2807.2004  1
2004 Burton DR, Desrosiers RC, Doms RW, Koff WC, Kwong PD, Moore JP, Nabel GJ, Sodroski J, Wilson IA, Wyatt RT. HIV vaccine design and the neutralizing antibody problem. Nature Immunology. 5: 233-6. PMID 14985706 DOI: 10.1038/Ni0304-233  1
2004 Zhu X, Wentworth P, Wentworth AD, Eschenmoser A, Lerner RA, Wilson IA. Probing the antibody-catalyzed water-oxidation pathway at atomic resolution. Proceedings of the National Academy of Sciences of the United States of America. 101: 2247-52. PMID 14982995 DOI: 10.1073/Pnas.0307311101  1
2004 Rudolph MG, Shen LQ, Lamontagne SA, Luz JG, Delaney JR, Ge Q, Cho BK, Palliser D, McKinley CA, Chen J, Wilson IA, Eisen HN. A peptide that antagonizes TCR-mediated reactions with both syngeneic and allogeneic agonists: functional and structural aspects. Journal of Immunology (Baltimore, Md. : 1950). 172: 2994-3002. PMID 14978103 DOI: 10.4049/Jimmunol.172.5.2994  1
2004 Lee HK, Scanlan CN, Huang CY, Chang AY, Calarese DA, Dwek RA, Rudd PM, Burton DR, Wilson IA, Wong CH. Reactivity-based one-pot synthesis of oligomannoses: defining antigens recognized by 2G12, a broadly neutralizing anti-HIV-1 antibody. Angewandte Chemie (International Ed. in English). 43: 1000-3. PMID 14966891 DOI: 10.1002/Anie.200353105  1
2004 Cheong CG, Wolan DW, Greasley SE, Horton PA, Beardsley GP, Wilson IA. Crystal structures of human bifunctional enzyme aminoimidazole-4-carboxamide ribonucleotide transformylase/IMP cyclohydrolase in complex with potent sulfonyl-containing antifolates. The Journal of Biological Chemistry. 279: 18034-45. PMID 14966129 DOI: 10.1074/Jbc.M313691200  1
2004 Stanfield RL, Gorny MK, Williams C, Zolla-Pazner S, Wilson IA. Structural rationale for the broad neutralization of HIV-1 by human monoclonal antibody 447-52D. Structure (London, England : 1993). 12: 193-204. PMID 14962380 DOI: 10.1016/J.Str.2004.01.003  1
2004 Wolan DW, Cheong CG, Greasley SE, Wilson IA. Structural insights into the human and avian IMP cyclohydrolase mechanism via crystal structures with the bound XMP inhibitor. Biochemistry. 43: 1171-83. PMID 14756553 DOI: 10.1021/Bi030162I  1
2004 Moody DB, Young DC, Cheng TY, Rosat JP, Roura-Mir C, O'Connor PB, Zajonc DM, Walz A, Miller MJ, Levery SB, Wilson IA, Costello CE, Brenner MB. T cell activation by lipopeptide antigens. Science (New York, N.Y.). 303: 527-31. PMID 14739458 DOI: 10.1126/Science.1089353  1
2004 Schwarzenbacher R, von Delft F, Canaves JM, Brinen LS, Dai X, Deacon AM, Elsliger MA, Eshaghi S, Floyd R, Godzik A, Grittini C, Grzechnik SK, Guda C, Jaroszewski L, Karlak C, ... ... Wilson IA, et al. Crystal structure of an iron-containing 1,3-propanediol dehydrogenase (TM0920) from Thermotoga maritima at 1.3 A resolution. Proteins. 54: 174-7. PMID 14705036 DOI: 10.1002/Prot.10594  1
2004 Page R, Nelson MS, von Delft F, Elsliger MA, Canaves JM, Brinen LS, Dai X, Deacon AM, Floyd R, Godzik A, Grittini C, Grzechnik SK, Jaroszewski L, Klock HE, Koesema E, ... ... Wilson IA, et al. Crystal structure of gamma-glutamyl phosphate reductase (TM0293) from Thermotoga maritima at 2.0 A resolution. Proteins. 54: 157-61. PMID 14705032 DOI: 10.1002/Prot.10562  1
2003 Scanlan CN, Pantophlet R, Wormald MR, Saphire EO, Calarese D, Stanfield R, Wilson IA, Katinger H, Dwek RA, Burton DR, Rudd PM. The carbohydrate epitope of the neutralizing anti-HIV-1 antibody 2G12. Advances in Experimental Medicine and Biology. 535: 205-18. PMID 14714897 DOI: 10.1007/978-1-4615-0065-0_13  1
2003 Saphire EO, Stanfield RL, Crispin MD, Morris G, Zwick MB, Pantophlet RA, Parren PW, Rudd PM, Dwek RA, Burton DR, Wilson IA. Crystal structure of an intact human IgG: antibody asymmetry, flexibility, and a guide for HIV-1 vaccine design. Advances in Experimental Medicine and Biology. 535: 55-66. PMID 14714888 DOI: 10.1007/978-1-4615-0065-0_4  1
2003 Stanfield RL, Ghiara JB, Saphire EO, Profy AT, Wilson IA. Recurring conformation of the human immunodeficiency virus type 1 gp120 V3 loop Virology. 315: 159-173. PMID 14592768 DOI: 10.1016/S0042-6822(03)00525-7  1
2003 Desharnais J, Hwang I, Zhang Y, Tavassoli A, Baboval J, Benkovic SJ, Wilson IA, Boger DL. Design, synthesis and biological evaluation of 10-CF3CO-DDACTHF analogues and derivatives as inhibitors of GAR Tfase and the de novo purine biosynthetic pathway. Bioorganic & Medicinal Chemistry. 11: 4511-21. PMID 13129587 DOI: 10.1016/S0968-0896(03)00458-9  1
2003 Marsilje TH, Hedrick MP, Desharnais J, Capps K, Tavassoli A, Zhang Y, Wilson IA, Benkovic SJ, Boger DL. 10-(2-benzoxazolcarbonyl)-5,10-dideaza-acyclic-5,6,7,8-tetrahydrofolic acid: a potential inhibitor of GAR transformylase and AICAR transformylase. Bioorganic & Medicinal Chemistry. 11: 4503-9. PMID 13129586 DOI: 10.1016/S0968-0896(03)00457-7  1
2003 Marsilje TH, Hedrick MP, Desharnais J, Tavassoli A, Zhang Y, Wilson IA, Benkovic SJ, Boger DL. Design, synthesis, and biological evaluation of simplified alpha-keto heterocycle, trifluoromethyl ketone, and formyl substituted folate analogues as potential inhibitors of GAR transformylase and AICAR transformylase. Bioorganic & Medicinal Chemistry. 11: 4487-501. PMID 13129585 DOI: 10.1016/S0968-0896(03)00456-5  1
2003 Wolan DW, Greasley SE, Wall MJ, Benkovic SJ, Wilson IA. Structure of avian AICAR transformylase with a multisubstrate adduct inhibitor beta-DADF identifies the folate binding site. Biochemistry. 42: 10904-14. PMID 12974624 DOI: 10.1021/Bi030106H  1
2003 Rader C, Turner JM, Heine A, Shabat D, Sinha SC, Wilson IA, Lerner RA, Barbas CF. A humanized aldolase antibody for selective chemotherapy and adaptor immunotherapy. Journal of Molecular Biology. 332: 889-99. PMID 12972259 DOI: 10.1016/S0022-2836(03)00992-6  1
2003 Schwarzenbacher R, Canaves JM, Brinen LS, Dai X, Deacon AM, Elsliger MA, Eshaghi S, Floyd R, Godzik A, Grittini C, Grzechnik SK, Guda C, Jaroszewski L, Karlak C, Klock HE, ... ... Wilson IA, et al. Crystal structure of uronate isomerase (TM0064) from Thermotoga maritima at 2.85 A resolution. Proteins. 53: 142-5. PMID 12945057 DOI: 10.1002/Prot.10462  1
2003 Calarese DA, Scanlan CN, Zwick MB, Deechongkit S, Mimura Y, Kunert R, Zhu P, Wormald MR, Stanfield RL, Roux KH, Kelly JW, Rudd PM, Dwek RA, Katinger H, Burton DR, ... Wilson IA, et al. Antibody domain exchange is an immunological solution to carbohydrate cluster recognition. Science (New York, N.Y.). 300: 2065-71. PMID 12829775 DOI: 10.1126/Science.1083182  1
2003 Zhang Y, Desharnais J, Marsilje TH, Li C, Hedrick MP, Gooljarsingh LT, Tavassoli A, Benkovic SJ, Olson AJ, Boger DL, Wilson IA. Rational design, synthesis, evaluation, and crystal structure of a potent inhibitor of human GAR Tfase: 10-(trifluoroacetyl)-5,10-dideazaacyclic-5,6,7,8-tetrahydrofolic acid. Biochemistry. 42: 6043-56. PMID 12755606 DOI: 10.1021/Bi034219C  1
2003 Zwick MB, Parren PW, Saphire EO, Church S, Wang M, Scott JK, Dawson PE, Wilson IA, Burton DR. Molecular features of the broadly neutralizing immunoglobulin G1 b12 required for recognition of human immunodeficiency virus type 1 gp120. Journal of Virology. 77: 5863-76. PMID 12719580 DOI: 10.1128/Jvi.77.10.5863-5876.2003  1
2003 Luz JG, Hassig CA, Pickle C, Godzik A, Meyer BJ, Wilson IA. XOL-1, primary determinant of sexual fate in C. elegans, is a GHMP kinase family member and a structural prototype for a class of developmental regulators. Genes & Development. 17: 977-90. PMID 12672694 DOI: 10.1101/Gad.1082303  1
2003 Redwan el-RM, Larsen NA, Zhou B, Wirsching P, Janda KD, Wilson IA. Expression and characterization of a humanized cocaine-binding antibody. Biotechnology and Bioengineering. 82: 612-8. PMID 12652485 DOI: 10.1002/Bit.10598  1
2003 Royle L, Roos A, Harvey DJ, Wormald MR, Van Gijlswijk-Janssen D, Redwan ERM, Wilson IA, Daha MR, Dwek RA, Rudd PM. Secretory IgA N- and O-glycans provide a link between the innate and adaptive immune systems Journal of Biological Chemistry. 278: 20140-20153. PMID 12637583 DOI: 10.1074/Jbc.M301436200  1
2003 An Y, Shao Y, Alory C, Matteson J, Sakisaka T, Chen W, Gibbs RA, Wilson IA, Balch WE. Geranylgeranyl switching regulates GDI-Rab GTPase recycling. Structure (London, England : 1993). 11: 347-57. PMID 12623022 DOI: 10.1016/S0969-2126(03)00034-0  1
2003 Wentworth P, Wentworth AD, Zhu X, Wilson IA, Janda KD, Eschenmoser A, Lerner RA. Evidence for the production of trioxygen species during antibody-catalyzed chemical modification of antigens. Proceedings of the National Academy of Sciences of the United States of America. 100: 1490-3. PMID 12576548 DOI: 10.1073/Pnas.0437831100  1
2003 Rudolph MG, Kelker MS, Schneider TR, Yeates TO, Oseroff V, Heidary DK, Jennings PA, Wilson IA. Use of multiple anomalous dispersion to phase highly merohedrally twinned crystals of interleukin-1beta. Acta Crystallographica. Section D, Biological Crystallography. 59: 290-8. PMID 12554939 DOI: 10.1107/S0907444902021704  1
2003 Brinen LS, Canaves JM, Dai X, Deacon AM, Elsliger MA, Eshaghi S, Floyd R, Godzik A, Grittini C, Grzechnik SK, Guda C, Jaroszewski L, Karlak C, Klock HE, Koesema E, ... ... Wilson IA, et al. Crystal structure of a zinc-containing glycerol dehydrogenase (TM0423) from Thermotoga maritima at 1.5 A resolution. Proteins. 50: 371-4. PMID 12486729 DOI: 10.1002/Prot.10302  1
2003 Pantophlet R, Ollmann Saphire E, Poignard P, Parren PW, Wilson IA, Burton DR. Fine mapping of the interaction of neutralizing and nonneutralizing monoclonal antibodies with the CD4 binding site of human immunodeficiency virus type 1 gp120. Journal of Virology. 77: 642-58. PMID 12477867 DOI: 10.1128/Jvi.77.1.642-658.2003  0.4
2003 DeSantis G, Liu J, Clark DP, Heine A, Wilson IA, Wong CH. Structure-based mutagenesis approaches toward expanding the substrate specificity of D-2-deoxyribose-5-phosphate aldolase. Bioorganic & Medicinal Chemistry. 11: 43-52. PMID 12467706 DOI: 10.1016/S0968-0896(02)00429-7  1
2003 Zhu X, Larsen NA, Basran A, Bruce NC, Wilson IA. Observation of an arsenic adduct in an acetyl esterase crystal structure. The Journal of Biological Chemistry. 278: 2008-14. PMID 12421810 DOI: 10.1074/Jbc.M210103200  1
2002 Wolan DW, Greasley SE, Beardsley GP, Wilson IA. Structural insights into the avian AICAR transformylase mechanism. Biochemistry. 41: 15505-13. PMID 12501179 DOI: 10.1021/Bi020505X  1
2002 Rudolph MG, Stevens J, Speir JA, Trowsdale J, Butcher GW, Joly E, Wilson IA. Crystal structures of two rat MHC class Ia (RT1-A) molecules that are associated differentially with peptide transporter alleles TAP-A and TAP-B. Journal of Molecular Biology. 324: 975-90. PMID 12470953 DOI: 10.1016/S0022-2836(02)01095-1  1
2002 Larsen NA, Heine A, de Prada P, Redwan el-R, Yeates TO, Landry DW, Wilson IA. Structure determination of a cocaine hydrolytic antibody from a pseudomerohedrally twinned crystal. Acta Crystallographica. Section D, Biological Crystallography. 58: 2055-9. PMID 12454464 DOI: 10.1107/S0907444902017420  1
2002 Zhang Y, Desharnais J, Greasley SE, Beardsley GP, Boger DL, Wilson IA. Crystal structures of human GAR Tfase at low and high pH and with substrate beta-GAR. Biochemistry. 41: 14206-15. PMID 12450384 DOI: 10.1021/Bi020522M  1
2002 Turner JM, Larsen NA, Basran A, Barbas CF, Bruce NC, Wilson IA, Lerner RA. Biochemical characterization and structural analysis of a highly proficient cocaine esterase. Biochemistry. 41: 12297-307. PMID 12369817 DOI: 10.1021/Bi026131P  1
2002 Kuhn P, Lesley SA, Mathews II, Canaves JM, Brinen LS, Dai X, Deacon AM, Elsliger MA, Eshaghi S, Floyd R, Godzik A, Grittini C, Grzechnik SK, Guda C, Hodgson KO, ... ... Wilson IA, et al. Crystal structure of thy1, a thymidylate synthase complementing protein from Thermotoga maritima at 2.25 A resolution. Proteins. 49: 142-5. PMID 12211025 DOI: 10.1002/Prot.10202  1
2002 Lesley SA, Kuhn P, Godzik A, Deacon AM, Mathews I, Kreusch A, Spraggon G, Klock HE, McMullan D, Shin T, Vincent J, Robb A, Brinen LS, Miller MD, McPhillips TM, ... ... Wilson IA, et al. Structural genomics of the Thermotoga maritima proteome implemented in a high-throughput structure determination pipeline. Proceedings of the National Academy of Sciences of the United States of America. 99: 11664-9. PMID 12193646 DOI: 10.1073/Pnas.142413399  1
2002 Marsilje TH, Labroli MA, Hedrick MP, Jin Q, Desharnais J, Baker SJ, Gooljarsingh LT, Ramcharan J, Tavassoli A, Zhang Y, Wilson IA, Beardsley GP, Benkovic SJ, Boger DL. 10-Formyl-5,10-dideaza-acyclic-5,6,7,8-tetrahydrofolic acid (10-formyl-DDACTHF): a potent cytotoxic agent acting by selective inhibition of human GAR Tfase and the de novo purine biosynthetic pathway. Bioorganic & Medicinal Chemistry. 10: 2739-49. PMID 12057663 DOI: 10.1016/S0968-0896(02)00102-5  1
2002 Saphire EO, Stanfield RL, Crispin MD, Parren PW, Rudd PM, Dwek RA, Burton DR, Wilson IA. Contrasting IgG structures reveal extreme asymmetry and flexibility. Journal of Molecular Biology. 319: 9-18. PMID 12051932 DOI: 10.1016/S0022-2836(02)00244-9  1
2002 Luz JG, Huang M, Garcia KC, Rudolph MG, Apostolopoulos V, Teyton L, Wilson IA. Structural comparison of allogeneic and syngeneic T cell receptor-peptide-major histocompatibility complex complexes: a buried alloreactive mutation subtly alters peptide presentation substantially increasing V(beta) Interactions. The Journal of Experimental Medicine. 195: 1175-86. PMID 11994422 DOI: 10.1084/Jem.20011644  0.8
2002 Huang M, Weissman JT, Wang C, Balch WE, Wilson IA. Protein engineering for crystallization of the GTPase Sar1 that regulates ER vesicle budding. Acta Crystallographica. Section D, Biological Crystallography. 58: 700-3. PMID 11914501 DOI: 10.1107/S090744490200238X  1
2002 Hotta K, Wilson IA, Hilvert D. Probing ligand recognition in the decarboxylase antibody 21D8: implications for the catalytic mechanism. Biochemistry. 41: 772-9. PMID 11790098 DOI: 10.1021/Bi0158167  0.36
2002 Larsen NA, Turner JM, Stevens J, Rosser SJ, Basran A, Lerner RA, Bruce NC, Wilson IA. Crystal structure of a bacterial cocaine esterase. Nature Structural Biology. 9: 17-21. PMID 11742345 DOI: 10.1038/Nsb742  1
2001 Huang M, Weissman JT, Beraud-Dufour S, Luan P, Wang C, Chen W, Aridor M, Wilson IA, Balch WE. Crystal structure of Sar1-GDP at 1.7 A resolution and the role of the NH2 terminus in ER export. The Journal of Cell Biology. 155: 937-48. PMID 11739406 DOI: 10.1083/Jcb.200106039  1
2001 Larsen NA, Heine A, Crane L, Cravatt BF, Lerner RA, Wilson IA. Structural basis for a disfavored elimination reaction in catalytic antibody 1D4. Journal of Molecular Biology. 314: 93-102. PMID 11724535 DOI: 10.1006/Jmbi.2001.5112  0.4
2001 Greasley SE, Marsilje TH, Cai H, Baker S, Benkovic SJ, Boger DL, Wilson IA. Unexpected formation of an epoxide-derived multisubstrate adduct inhibitor on the active site of GAR transformylase Biochemistry. 40: 13538-13547. PMID 11695901 DOI: 10.1021/Bi011482+  1
2001 Wentworth P, Jones LH, Wentworth AD, Zhu X, Larsen NA, Wilson IA, Xu X, Goddard WA, Janda KD, Eschenmoser A, Lerner RA. Antibody catalysis of the oxidation of water. Science (New York, N.Y.). 293: 1806-11. PMID 11546867 DOI: 10.1126/Science.1062722  1
2001 Saphire EO, Parren PW, Pantophlet R, Zwick MB, Morris GM, Rudd PM, Dwek RA, Stanfield RL, Burton DR, Wilson IA. Crystal structure of a neutralizing human IGG against HIV-1: a template for vaccine design. Science (New York, N.Y.). 293: 1155-9. PMID 11498595 DOI: 10.1126/Science.1061692  1
2001 Larsen NA, Zhou B, Heine A, Wirsching P, Janda KD, Wilson IA. Crystal structure of a cocaine-binding antibody. Journal of Molecular Biology. 311: 9-15. PMID 11469854 DOI: 10.1006/Jmbi.2001.4839  1
2001 Wilson IA, Stanfield RL. Unraveling the mysteries of gammadelta T cell recognition. Nature Immunology. 2: 579-81. PMID 11429538 DOI: 10.1038/89718  1
2001 Greasley SE, Horton P, Ramcharan J, Beardsley GP, Benkovic SJ, Wilson IA. Crystal structure of a bifunctional transformylase and cyclohydrolase enzyme in purine biosynthesis. Nature Structural Biology. 8: 402-6. PMID 11323713 DOI: 10.1038/87555  1
2001 Rudolph MG, Speir JA, Brunmark A, Mattsson N, Jackson MR, Peterson PA, Teyton L, Wilson IA. The crystal structures of Kbm1 and Kbm8 reveal that subtle changes in the peptide environment impact thermostability and alloreactivity Immunity. 14: 231-242. PMID 11290333 DOI: 10.1016/S1074-7613(01)00105-4  1
2001 Rudd PM, Elliott T, Cresswell P, Wilson IA, Dwek RA. Glycosylation and the immune system. Science (New York, N.Y.). 291: 2370-6. PMID 11269318 DOI: 10.1126/Science.291.5512.2370  1
2001 Wolan DW, Teyton L, Rudolph MG, Villmow B, Bauer S, Busch DH, Wilson IA. Crystal structure of the murine NK cell-activating receptor NKG2D at 1.95 A. Nature Immunology. 2: 248-54. PMID 11224525 DOI: 10.1038/85311  1
2001 Mazlo J, Stanfield RL, Wilson IA, Hinrichs SH, Stezowski JJ. Preliminary X-ray diffraction studies of the transcriptional inhibitory antibody Fab41.4. Acta Crystallographica. Section D, Biological Crystallography. 57: 462-4. PMID 11223533 DOI: 10.1107/S0907444901001135  1
2001 Speir JA, Stevens J, Joly E, Butcher GW, Wilson IA. Two different, highly exposed, bulged structures for an unusually long peptide bound to rat MHC class I RT1-Aa. Immunity. 14: 81-92. PMID 11163232 DOI: 10.1016/S1074-7613(01)00091-7  1
2001 Saphire EO, Parren PW, Barbas CF, Burton DR, Wilson IA. Crystallization and preliminary structure determination of an intact human immunoglobulin, b12: an antibody that broadly neutralizes primary isolates of HIV-1. Acta Crystallographica. Section D, Biological Crystallography. 57: 168-71. PMID 11134947 DOI: 10.1107/S0907444900017376  1
2000 Luan P, Heine A, Zeng K, Moyer B, Greasely SE, Kuhn P, Balch WE, Wilson IA. A new functional domain of guanine nucleotide dissociation inhibitor (alpha-GDI) involved in Rab recycling. Traffic (Copenhagen, Denmark). 1: 270-81. PMID 11208110 DOI: 10.1034/J.1600-0854.2000.010309.X  1
2000 Hotta K, Lange H, Tantillo DJ, Houk KN, Hilvert D, Wilson IA. Catalysis of decarboxylation by a preorganized heterogeneous microenvironment: crystal structures of abzyme 21D8. Journal of Molecular Biology. 302: 1213-25. PMID 11183784 DOI: 10.1006/Jmbi.2000.4503  0.36
2000 Stratmann T, Apostolopoulos V, Mallet-Designe V, Corper AL, Scott CA, Wilson IA, Kang AS, Teyton L. The I-Ag7 MHC class II molecule linked to murine diabetes is a promiscuous peptide binder. Journal of Immunology (Baltimore, Md. : 1950). 165: 3214-25. PMID 10975837 DOI: 10.4049/Jimmunol.165.6.3214  1
2000 Reyes VM, Greasley SE, Stura EA, Beardsley GP, Wilson IA. Crystallization and preliminary crystallographic investigations of avian 5-aminoimidazole-4-carboxamide ribonucleotide transformylase-inosine monophosphate cyclohydrolase expressed in Escherichia coli. Acta Crystallographica. Section D, Biological Crystallography. 56: 1051-4. PMID 10944351 DOI: 10.1107/S0907444900007800  1
2000 Corper AL, Stratmann T, Apostolopoulos V, Scott CA, Garcia KC, Kang AS, Wilson IA, Teyton L. A structural framework for deciphering the link between I-A(g7) and autoimmune diabetes Science. 288: 505-511. PMID 10775108 DOI: 10.1126/Science.288.5465.505  1
2000 Karlstrom A, Zhong G, Rader C, Larsen NA, Heine A, Fuller R, List B, Tanaka F, Wilson IA, Barbas CF, Lerner RA. Using antibody catalysis to study the outcome of multiple evolutionary trials of a chemical task. Proceedings of the National Academy of Sciences of the United States of America. 97: 3878-83. PMID 10760259 DOI: 10.1073/Pnas.97.8.3878  1
2000 Degano M, Garcia KC, Apostolopoulos V, Rudolph MG, Teyton L, Wilson IA. A functional hot spot for antigen recognition in a superagonist TCR/MHC complex. Immunity. 12: 251-61. PMID 10755612 DOI: 10.1016/S1074-7613(00)80178-8  0.8
1999 Moody DB, Besra GS, Wilson IA, Porcelli SA. The molecular basis of CD1-mediated presentation of lipid antigens. Immunological Reviews. 172: 285-96. PMID 10631954 DOI: 10.1111/J.1600-065X.1999.Tb01373.X  1
1999 Rudd PM, Wormald MR, Stanfield RL, Huang M, Mattsson N, Speir JA, DiGennaro JA, Fetrow JS, Dwek RA, Wilson IA. Roles for glycosylation of cell surface receptors involved in cellular immune recognition. Journal of Molecular Biology. 293: 351-66. PMID 10529350 DOI: 10.1006/Jmbi.1999.3104  1
1999 Garcia KC, Teyton L, Wilson IA. Structural basis of T cell recognition. Annual Review of Immunology. 17: 369-97. PMID 10358763 DOI: 10.1146/Annurev.Immunol.17.1.369  0.8
1999 Gruber K, Zhou B, Houk KN, Lerner RA, Shevlin CG, Wilson IA. Structural basis for antibody catalysis of a disfavored ring closure reaction. Biochemistry. 38: 7062-74. PMID 10353817 DOI: 10.1021/Bi990210S  1
1999 Middleton SA, Barbone FP, Johnson DL, Thurmond RL, You Y, McMahon FJ, Jin R, Livnah O, Tullai J, Farrell FX, Goldsmith MA, Wilson IA, Jolliffe LK. Shared and unique determinants of the erythropoietin (EPO) receptor are important for binding EPO and EPO mimetic peptide. The Journal of Biological Chemistry. 274: 14163-9. PMID 10318834 DOI: 10.1074/Jbc.274.20.14163  1
1999 Remy I, Wilson IA, Michnick SW. Erythropoietin receptor activation by a ligand-induced conformation change. Science (New York, N.Y.). 283: 990-3. PMID 9974393 DOI: 10.1126/Science.283.5404.990  1
1999 Livnah O, Stura EA, Middleton SA, Johnson DL, Jolliffe LK, Wilson IA. Crystallographic evidence for preformed dimers of erythropoietin receptor before ligand activation. Science (New York, N.Y.). 283: 987-90. PMID 9974392 DOI: 10.1126/Science.283.5404.987  1
1998 Cai Z, Brunmark AB, Luxembourg AT, Garcia KC, Degano M, Teyton L, Wilson I, Peterson PA, Sprent J, Jackson MR. Probing the activation requirements for naive CD8+ T cells with Drosophila cell transfectants as antigen presenting cells Immunological Reviews. 165: 249-265. PMID 9850865 DOI: 10.1111/J.1600-065X.1998.Tb01243.X  1
1998 Livnah O, Johnson DL, Stura EA, Farrel FX, Barbone FP, You Y, Liu KD, Goldsmith MA, He W, Krause CD, Pestka S, Jolliffe LK, Wilson IA. An antagonist peptide-EPO receptor complex suggests that receptor dimerization is not sufficient for activation Nature Structural Biology. 5: 993-1004. PMID 9808045 DOI: 10.1038/2965  1
1998 Su Y, Yamashita MM, Greasley SE, Mullen CA, Shim JH, Jennings PA, Benkovic SJ, Wilson IA. A pH-dependent stabilization of an active site loop observed from low and high pH crystal structures of mutant monomeric glycinamide ribonucleotide transformylase at 1.8 to 1.9 A. Journal of Molecular Biology. 281: 485-99. PMID 9698564 DOI: 10.1006/Jmbi.1998.1931  1
1998 Speir JA, Garcia KC, Brunmark A, Degano M, Peterson PA, Teyton L, Wilson IA. Structural basis of 2C TCR allorecognition of H-2L(d) peptide complexes Immunity. 8: 553-562. PMID 9620676 DOI: 10.1016/S1074-7613(00)80560-9  1
1998 Manning TC, Schlueter CJ, Brodnicki TC, Parke EA, Speir JA, Garcia KC, Teyton L, Wilson IA, Kranz DM. Alanine scanning mutagenesis of an αβ T cell receptor: Mapping the energy of antigen recognition Immunity. 8: 413-425. PMID 9586632 DOI: 10.1016/S1074-7613(00)80547-6  1
1998 Scott CA, Peterson PA, Teyton L, Wilson IA. Crystal structures of two I-A(d)-peptide complexes reveal that high affinity can be achieved without large anchor residues Immunity. 8: 319-329. PMID 9529149 DOI: 10.1016/S1074-7613(00)80537-3  1
1998 Johnson DL, Farrell FX, Barbone FP, McMahon FJ, Tullai J, Hoey K, Livnah O, Wrighton NC, Middleton SA, Loughney DA, Stura EA, Dower WJ, Mulcahy LS, Wilson IA, Jolliffe LK. Identification of a 13 amino acid peptide mimetic of erythropoietin and description of amino acids critical for the mimetic activity of EMP1. Biochemistry. 37: 3699-710. PMID 9521688 DOI: 10.1021/Bi971956Y  1
1998 Scott CA, Christopher Garcia K, Stura EA, Peterson PA, Wilson IA, Teyton L. Engineering protein for X-ray crystallography: The murine major histocompatibility complex class II molecule I-A(d) Protein Science. 7: 413-418. PMID 9521118 DOI: 10.1002/Pro.5560070222  1
1998 Heine A, Stura EA, Yli-Kauhaluoma JT, Gao C, Deng Q, Beno BR, Houk KN, Janda KD, Wilson IA. An antibody exo Diels-Alderase inhibitor complex at 1.95 angstrom resolution. Science (New York, N.Y.). 279: 1934-40. PMID 9506943 DOI: 10.1126/Science.279.5358.1934  1
1998 Garcia KC, Degano M, Pease LR, Huang M, Peterson PA, Teyton L, Wilson IA. Structural basis of plasticity in T cell receptor recognition of a self peptide-MHC antigen Science. 279: 1166-1172. PMID 9469799 DOI: 10.1126/Science.279.5354.1166  1
1997 Wilson IA, Garcia KC. T-cell receptor structure and TCR complexes. Current Opinion in Structural Biology. 7: 839-48. PMID 9434905 DOI: 10.1016/S0959-440X(97)80156-X  0.8
1997 Barbas CF, Heine A, Zhong G, Hoffmann T, Gramatikova S, Björnestedt R, List B, Anderson J, Stura EA, Wilson IA, Lerner RA. Immune versus natural selection: antibody aldolases with enzymic rates but broader scope. Science (New York, N.Y.). 278: 2085-92. PMID 9405338 DOI: 10.1126/Science.278.5346.2085  1
1997 Garcia KC, Tallquist MD, Pease LR, Brunmark A, Scott CA, Degano M, Stura EA, Peterson PA, Wilson IA, Teyton L. αβ T cell receptor interactions with syngeneic and allogeneic ligands: Affinity measurements and crystallization Proceedings of the National Academy of Sciences of the United States of America. 94: 13838-13843. PMID 9391114 DOI: 10.1073/Pnas.94.25.13838  1
1997 Zeng ZH, Castaño AR, Segelke BW, Stura EA, Peterson PA, Wilson IA. Crystal structure of mouse CD1: An MHC-like fold with a large hydrophobic binding groove Science. 277: 339-345. PMID 9219685 DOI: 10.1126/Science.277.5324.339  1
1997 He M, Gani M, Livnah O, Stura EA, Beale D, Coley J, Wilson IA, Taussig MJ. Sequence, specificity and crystallization of an oestrone-3-glucuronide antibody (3910). Immunology. 90: 632-9. PMID 9176119 DOI: 10.1046/J.1365-2567.1997.00099.X  1
1996 Wu SK, Zeng K, Wilson IA, Balch WE. Structural insights into the function of the Rab GDI superfamily Trends in Biochemical Sciences. 21: 472-476. PMID 9009830 DOI: 10.1016/S0968-0004(96)10062-1  1
1996 Garcia KC, Scott CA, Brunmark A, Carbone FR, Peterson PA, Wilson IA, Teyton L. CD8 enhances formation of stable T-cell receptor/MHC class I molecule complexes Nature. 384: 577-581. PMID 8955273 DOI: 10.1038/384577A0  1
1996 Livnah O, Stura EA, Johnson DL, Middleton SA, Mulcahy LS, Wrighton NC, Dower WJ, Jolliffe LK, Wilson IA. Functional mimicry of a protein hormone by a peptide agonist: the EPO receptor complex at 2.8 A. Science (New York, N.Y.). 273: 464-71. PMID 8662530 DOI: 10.1126/Science.273.5274.464  1
1996 Scott CA, Garcia KC, Carbone FR, Wilson IA, Teyton L. Role of chain pairing for the production of functional soluble IA major histocompatibility complex class II molecules. The Journal of Experimental Medicine. 183: 2087-95. PMID 8642319 DOI: 10.1084/Jem.183.5.2087  0.8
1996 Schalk I, Zeng K, Wu SK, Stura EA, Matteson J, Huang M, Tandon A, Wilson IA, Balch WE. Structure and mutational analysis of Rab GDP-dissociation inhibitor. Nature. 381: 42-8. PMID 8609986 DOI: 10.1038/381042A0  1
1995 Lewicki H, Tishon A, Borrow P, Evans CF, Gairin JE, Hahn KM, Jewell DA, Wilson IA, Oldstone MB. CTL escape viral variants. I. Generation and molecular characterization. Virology. 210: 29-40. PMID 7793078 DOI: 10.1006/Viro.1995.1314  1
1995 Klein C, Chen P, Arevalo JH, Stura EA, Marolewski A, Warren MS, Benkovic SJ, Wilson IA. Towards structure-based drug design: crystal structure of a multisubstrate adduct complex of glycinamide ribonucleotide transformylase at 1.96 A resolution. Journal of Molecular Biology. 249: 153-75. PMID 7776369 DOI: 10.1006/Jmbi.1995.0286  1
1995 Stanfield RL, Wilson IA. Protein-peptide interactions. Current Opinion in Structural Biology. 5: 103-13. PMID 7773739 DOI: 10.1016/0959-440X(95)80015-S  1
1995 Fremont DH, Stura EA, Matsumura M, Peterson PA, Wilson IA. Crystal structure of an H-2Kb-ovalbumin peptide complex reveals the interplay of primary and secondary anchor positions in the major histocompatibility complex binding groove Proceedings of the National Academy of Sciences of the United States of America. 92: 2479-2483. PMID 7708669 DOI: 10.1073/Pnas.92.7.2479  1
1995 Wilson IA, Stanfield RL. A Trojan horse with a sweet tooth. Nature Structural Biology. 2: 433-6. PMID 7664102 DOI: 10.1038/Nsb0695-433  1
1994 Haynes MR, Stura EA, Hilvert D, Wilson IA. Routes to catalysis: structure of a catalytic antibody and comparison with its natural counterpart. Science (New York, N.Y.). 263: 646-52. PMID 8303271 DOI: 10.1126/Science.8303271  1
1994 Haynes MR, Stura EA, Hilvert D, Wilson IA. Crystallization and preliminary structural studies of a chorismate mutase catalytic antibody complexed with a transition state analog. Proteins. 18: 198-200. PMID 8159668 DOI: 10.1002/Prot.340180211  1
1994 Arevalo JH, Hassig CA, Stura EA, Sims MJ, Taussig MJ, Wilson IA. Structural analysis of antibody specificity: Detailed comparison of five Fab′-steroid complexes Journal of Molecular Biology. 241: 663-690. PMID 8071992 DOI: 10.1006/Jmbi.1994.1543  1
1994 Schalk IJ, Stura EA, Mattesen J, Wilson IA, Balch WE. Crystallization and preliminary crystallographic data for Rab guanine nucleotide dissociation inhibitor (RabGDI) from bovine brain Journal of Molecular Biology. 244: 469-473. PMID 7990134 DOI: 10.1006/Jmbi.1994.1744  1
1994 Wilson IA, Stanfield RL, Jewell DA, Ghiara JB, Fremont DH, Stura EA. Immune recognition of viral antigens Infectious Agents and Disease. 3: 155-162. PMID 7812653  1
1994 Stanfield RL, Wilson IA. Antigen-induced conformational changes in antibodies: a problem for structural prediction and design. Trends in Biotechnology. 12: 275-9. PMID 7765075 DOI: 10.1016/0167-7799(94)90139-2  1
1994 Churchill ME, Stura EA, Pinilla C, Appel JR, Houghten RA, Kono DH, Balderas RS, Fieser GG, Schulze-Gahmen U, Wilson IA. Crystal structure of a peptide complex of anti-influenza peptide antibody Fab 26/9. Comparison of two different antibodies bound to the same peptide antigen. Journal of Molecular Biology. 241: 534-56. PMID 7520084 DOI: 10.1006/Jmbi.1994.1530  1
1993 Wilson IA, Fremont DH. Structural analysis of MHC class I molecules with bound peptide antigens. Seminars in Immunology. 5: 75-80. PMID 8504218 DOI: 10.1006/Smim.1993.1011  1
1993 Fremont DH, Anderson DH, Wilson IA, Dennis EA, Xuong NH. Crystal structure of phospholipase A2 from Indian cobra reveals a trimeric association. Proceedings of the National Academy of Sciences of the United States of America. 90: 342-6. PMID 8419939 DOI: 10.1073/Pnas.90.1.342  1
1993 Schulze-Gahmen U, Rini JM, Wilson IA. Detailed analysis of the free and bound conformations of an antibody. X-ray structures of Fab 17/9 and three different Fab-peptide complexes. Journal of Molecular Biology. 234: 1098-118. PMID 8263915 DOI: 10.1006/Jmbi.1993.1663  1
1992 Rini JM, Schulze-Gahmen U, Wilson IA. Structural evidence for induced fit as a mechanism for antibody-antigen recognition. Science (New York, N.Y.). 255: 959-65. PMID 1546293 DOI: 10.1126/Science.1546293  1
1992 Stura EA, Matsumura M, Fremont DH, Saito Y, Peterson PA, Wilson LA. Crystallization of murine major histocompatibility complex class I H-2Kb with single peptides Journal of Molecular Biology. 228: 975-982. PMID 1469730 DOI: 10.1016/0022-2836(92)90881-J  0.28
1992 Matsumura M, Fremont DH, Peterson PA, Wilson IA. Emerging principles for the recognition of peptide antigens by MHC class I molecules Science. 257: 927-934. PMID 1323878 DOI: 10.1126/Science.1323878  1
1992 Fremont DH, Matsumura M, Stura EA, Peterson PA, Wilson IA. Crystal structures of two viral peptides in complex with murine MHC class I H-2Kb Science. 257: 919-927. PMID 1323877 DOI: 10.1126/Science.1323877  1
1992 Stura EA, Nemerow GR, Wilson IA. Strategies in the crystallization of glycoproteins and protein complexes Journal of Crystal Growth. 122: 273-285. DOI: 10.1016/0022-0248(92)90256-I  1
1991 Wilson IA, Stanfield RL, Rini JM, Arevalo JH, Schulze-Gahmen U, Fremont DH, Stura EA. Structural aspects of antibodies and antibody-antigen complexes. Ciba Foundation Symposium. 159: 13-28; discussion 28. PMID 1959445  1
1991 Wilson IA, Rini JM, Fremont DH, Fieser GG, Stura EA. X-ray crystallographic analysis of free and antigen-complexed Fab fragments to investigate structural basis of immune recognition. Methods in Enzymology. 203: 153-76. PMID 1762555 DOI: 10.1016/0076-6879(91)03009-6  1
1988 White JM, Wilson IA. Anti-peptide antibodies detect steps in a protein conformational change: low-pH activation of the influenza virus hemagglutinin. The Journal of Cell Biology. 105: 2887-96. PMID 2447101 DOI: 10.1083/Jcb.105.6.2887  0.32
1987 Smith SG, Lewis M, Aschaffenburg R, Fenna RE, Wilson IA, Sundaralingam M, Stuart DI, Phillips DC. Crystallographic analysis of the three-dimensional structure of baboon alpha-lactalbumin at low resolution. Homology with lysozyme. The Biochemical Journal. 242: 353-60. PMID 3593255 DOI: 10.1042/Bj2420353  0.92
1985 Dyson HJ, Cross KJ, Houghten RA, Wilson IA, Wright PE, Lerner RA. The immunodominant site of a synthetic immunogen has a conformational preference in water for a type-II reverse turn. Nature. 318: 480-3. PMID 4069219 DOI: 10.1038/318480a0  1
1985 Wilson IA, Haft DH, Getzoff ED, Tainer JA, Lerner RA, Brenner S. Identical short peptide sequences in unrelated proteins can have different conformations: A testing ground for theories of immune recognition Proceedings of the National Academy of Sciences of the United States of America. 82: 5255-5259. PMID 2410917 DOI: 10.1073/Pnas.82.16.5255  1
1983 Wilson IA, Ladner RC, Skehel JJ, Wiley DC. The structure and role of the carbohydrate moieties of influenza virus haemagglutinin. Biochemical Society Transactions. 11: 145-7. PMID 6873453 DOI: 10.1042/Bst0110145  0.72
1983 Wilson IA, Ladner RC, Skehel JJ, Wiley DC. The structure and role of the carbohydrate moieties of influenza virus haemagglutinin. Biochemical Society Transactions. 11: 145-7. PMID 6662272  0.72
1983 Krystal M, Young JF, Palese P, Wilson IA, Skehel JJ, Wiley DC. Sequential mutations in hemagglutinins of influenza B virus isolates: definition of antigenic domains. Proceedings of the National Academy of Sciences of the United States of America. 80: 4527-31. PMID 6192436 DOI: 10.1073/Pnas.80.14.4527  0.72
1981 Wilson IA, Skehel JJ, Wiley DC. Structure of the haemagglutinin membrane glycoprotein of influenza virus at 3 A resolution. Nature. 289: 366-73. PMID 7464906 DOI: 10.1038/289366A0  0.72
1981 Wiley DC, Wilson IA, Skehel JJ. Structural identification of the antibody-binding sites of Hong Kong influenza haemagglutinin and their involvement in antigenic variation. Nature. 289: 373-8. PMID 6162101 DOI: 10.1038/289373A0  0.72
1981 Alber T, Banner DW, Bloomer AC, Petsko GA, Phillips D, Rivers PS, Wilson IA. On the three-dimensional structure and catalytic mechanism of triose phosphate isomerase Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences. 293: 159-171. PMID 6115415 DOI: 10.1098/Rstb.1981.0069  0.92
1978 Petsko GA, Phillips DC, Williams RJ, Wilson IA. On the protein crystal chemistry of chloroplatinite ions: general principles and interactions with triose phosphate isomerase. Journal of Molecular Biology. 120: 345-59. PMID 650685 DOI: 10.1016/0022-2836(78)90423-0  0.92
1978 Phillips DC, Sternberg MJ, Thornton JM, Wilson IA. An analysis of the structure of triose phosphate isomerase and its comparison with lactate dehydrogenase. Journal of Molecular Biology. 119: 329-51. PMID 633372 DOI: 10.1016/0022-2836(78)90440-0  0.92
1977 Phillips DC, Rivers PS, Sternberg MJ, Thornton JM, Wilson IA. An analysis of the three-dimensional structure of chicken triose phosphate isomerase. Biochemical Society Transactions. 5: 642-7. PMID 902882 DOI: 10.1042/Bst0050642  0.92
1976 Banner DW, Bloomer Ac, Petsko GA, Phillips DC, Wilson IA. Atomic coordinates for triose phosphate isomerase from chicken muscle. Biochemical and Biophysical Research Communications. 72: 146-55. PMID 985462 DOI: 10.1016/0006-291X(76)90972-4  0.92
1976 Browne CA, Campbell ID, Kiener PA, Phillips DC, Waley SG, Wilson IA. Studies of the histidine residues of triose phosphate isomerase by proton magnetic resonance and x-ray crystallography. Journal of Molecular Biology. 100: 319-43. PMID 3655 DOI: 10.1016/S0022-2836(76)80066-6  0.92
1975 Banner DW, Bloomer AC, Petsko GA, Phillips DC, Pogson CI, Wilson IA, Corran PH, Furth AJ, Milman JD, Offord RE, Priddle JD, Waley SG. Structure of chicken muscle triose phosphate isomerase determined crystallographically at 2.5 angstrom resolution using amino acid sequence data. Nature. 255: 609-14. PMID 1134550 DOI: 10.1038/255609A0  0.92
Show low-probability matches.