| Year |
Citation |
Score |
| 2024 |
Greene KS, Choi A, Yang N, Chen M, Li R, Qiu Y, Ezzatpour S, Rojas KS, Shen J, Wilson KF, Katt WP, Aguilar HC, Lukey MJ, Whittaker GR, Cerione RA. Glutamine metabolism Is essential for coronavirus replication in host cells and in mice. The Journal of Biological Chemistry. 108063. PMID 39662828 DOI: 10.1016/j.jbc.2024.108063 |
0.714 |
|
| 2023 |
Greene KS, Choi A, Chen M, Yang N, Li R, Qiu Y, Lukey MJ, Rojas KS, Shen J, Wilson KF, Katt WP, Whittaker GR, Cerione RA. Inhibiting Glutamine Metabolism Blocks Coronavirus Replication in Mammalian Cells. Biorxiv : the Preprint Server For Biology. PMID 37808692 DOI: 10.1101/2023.09.27.559756 |
0.719 |
|
| 2023 |
Erstling JA, Bag N, Gardinier TC, Kohle FFE, DomNwachukwu N, Butler SD, Kao T, Ma K, Turker MZ, Feuer GB, Lee R, Naguib N, Tallman JF, Malarkey HF, Tsaur L, ... ... Cerione RA, et al. Overcoming Barriers Associated with Oral Delivery of Differently Sized Fluorescent Core-Shell Silica Nanoparticles. Advanced Materials (Deerfield Beach, Fla.). e2305937. PMID 37689973 DOI: 10.1002/adma.202305937 |
0.452 |
|
| 2023 |
Teran OY, Zanotelli MR, Lin MJ, Cerione RA, Wilson KF. Dock7 regulates AKT and mTOR/S6K activity required for the transformed phenotypes and survival of cancer cells. Biorxiv : the Preprint Server For Biology. PMID 36711811 DOI: 10.1101/2023.01.03.522657 |
0.334 |
|
| 2022 |
Chang WH, Liu Y, Hammes EA, Bryant KL, Cerione RA, Antonyak MA. Oncogenic RAS promotes MYC protein stability by upregulating the expression of the inhibitor of apoptosis protein family member Survivin. The Journal of Biological Chemistry. 299: 102842. PMID 36581205 DOI: 10.1016/j.jbc.2022.102842 |
0.333 |
|
| 2022 |
Latifkar A, Wang F, Mullmann JJ, Panizza E, Fernandez IR, Ling L, Miller AD, Fischbach C, Weiss RS, Lin H, Cerione RA, Antonyak MA. IGF2BP2 promotes cancer progression by degrading the RNA transcript encoding a v-ATPase subunit. Proceedings of the National Academy of Sciences of the United States of America. 119: e2200477119. PMID 36322753 DOI: 10.1073/pnas.2200477119 |
0.803 |
|
| 2022 |
Nguyen TT, Ramachandran S, Hill MJ, Cerione RA. Mechanistic basis for the allosteric activation of mitochondrial glutaminase C, a key driver of glutamine metabolism in cancer cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 35560567 DOI: 10.1096/fasebj.2022.36.S1.R2820 |
0.313 |
|
| 2022 |
Wang F, Latifkar A, Mullmann J, Panizza E, Fernandez I, Ling L, Miller A, Fischbach C, Weiss R, Lin H, Cerione R, Antonyak M. IGF2BP2 Promotes Cancer Progression by Degrading the RNA Transcript Encoding a v-ATPase Subunit. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 35552659 DOI: 10.1096/fasebj.2022.36.S1.L7433 |
0.577 |
|
| 2021 |
Gao Y, Eskici G, Ramachandran S, Poitevin F, Seven AB, Panova O, Skiniotis G, Cerione RA. Structure of the visual signaling complex between transducin and phosphodiesterase 6. Molecular Cell. 81: 2496. PMID 34087182 DOI: 10.1016/j.molcel.2021.05.006 |
0.573 |
|
| 2021 |
Abril YLN, Fernandez IR, Hong JY, Chiang YL, Kutateladze DA, Zhao Q, Yang M, Hu J, Sadhukhan S, Li B, He B, Remick B, Bai JJ, Mullmann J, Wang F, ... ... Cerione RA, et al. Pharmacological and genetic perturbation establish SIRT5 as a promising target in breast cancer. Oncogene. PMID 33479498 DOI: 10.1038/s41388-020-01637-w |
0.567 |
|
| 2021 |
Wang J, Zhuang X, Greene KS, Si H, Antonyak MA, Druso JE, Wilson KF, Cerione RA, Feng Q, Wang H. Cdc42 functions as a regulatory node for tumour-derived microvesicle biogenesis. Journal of Extracellular Vesicles. 10: e12051. PMID 33473262 DOI: 10.1002/jev2.12051 |
0.535 |
|
| 2021 |
Chang WH, Cerione RA, Antonyak MA. Extracellular Vesicles and Their Roles in Cancer Progression. Methods in Molecular Biology (Clifton, N.J.). 2174: 143-170. PMID 32813249 DOI: 10.1007/978-1-0716-0759-6_10 |
0.405 |
|
| 2020 |
Gao Y, Eskici G, Ramachandran S, Poitevin F, Seven AB, Panova O, Skiniotis G, Cerione RA. Structure of the Visual Signaling Complex between Transducin and Phosphodiesterase 6. Molecular Cell. PMID 33007200 DOI: 10.1016/j.molcel.2020.09.013 |
0.644 |
|
| 2020 |
Lukey MJ, Greene KS, Cerione RA. Lysine succinylation and SIRT5 couple nutritional status to glutamine catabolism. Molecular & Cellular Oncology. 7: 1735284. PMID 32391426 DOI: 10.1080/23723556.2020.1735284 |
0.737 |
|
| 2020 |
Yamashita D, Minata M, Ibrahim AN, Yamaguchi S, Coviello V, Bernstock JD, Harada S, Cerione RA, Tannous BA, La Motta C, Nakano I. Identification of ALDH1A3 as a viable therapeutic target in breast cancer metastasis-initiating cells. Molecular Cancer Therapeutics. PMID 32127468 DOI: 10.1158/1535-7163.Mct-19-0461 |
0.344 |
|
| 2020 |
Endo M, Druso JE, Cerione RA. The two splice variant forms of Cdc42 exert distinct and essential functions in neurogenesis. The Journal of Biological Chemistry. PMID 32071086 DOI: 10.1074/Jbc.Ra119.011837 |
0.377 |
|
| 2019 |
Li Y, Ramachandran S, Nguyen TT, Stalnecker CA, Cerione RA, Erickson JW. The activation loop and substrate-binding cleft of glutaminase C are allosterically coupled. The Journal of Biological Chemistry. PMID 31871054 DOI: 10.1074/Jbc.Ra119.010314 |
0.375 |
|
| 2019 |
Greene KS, Lukey MJ, Wang X, Blank B, Druso JE, Lin MJ, Stalnecker CA, Zhang C, Negrón Abril Y, Erickson JW, Wilson KF, Lin H, Weiss RS, Cerione RA. SIRT5 stabilizes mitochondrial glutaminase and supports breast cancer tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America. PMID 31843902 DOI: 10.1073/Pnas.1911954116 |
0.799 |
|
| 2019 |
Hur YH, Cerione RA, Antonyak MA. Extracellular Vesicles and Their Roles in Stem Cell Biology: Concise Review. Stem Cells (Dayton, Ohio). PMID 31828924 DOI: 10.1002/Stem.3140 |
0.342 |
|
| 2019 |
Bordeleau F, Wang W, Simmons A, Antonyak MA, Cerione RA, Reinhart-King CA. Tissue transglutaminase regulates tumor cell tensional homeostasis by increasing contractility. Journal of Cell Science. PMID 31822629 DOI: 10.1242/Jcs.231134 |
0.429 |
|
| 2019 |
Lukey MJ, Cluntun AA, Katt WP, Lin MJ, Druso JE, Ramachandran S, Erickson JW, Le HH, Wang ZE, Blank B, Greene KS, Cerione RA. Liver-Type Glutaminase GLS2 Is a Druggable Metabolic Node in Luminal-Subtype Breast Cancer. Cell Reports. 29: 76-88.e7. PMID 31577957 DOI: 10.1016/J.Celrep.2019.08.076 |
0.792 |
|
| 2019 |
Katt WP, Lukey MJ, Cerione RA. Starving the Devourer: Cutting Cancer Off from Its Favorite Foods. Cell Chemical Biology. 26: 1197-1199. PMID 31539503 DOI: 10.1016/J.Chembiol.2019.09.005 |
0.734 |
|
| 2019 |
Katt WP, Cerione RA. Inhibition of cancer metabolism: a patent landscape. Pharmaceutical Patent Analyst. PMID 31414969 DOI: 10.4155/Ppa-2019-0012 |
0.367 |
|
| 2019 |
Gao Y, Hu H, Ramachandran S, Erickson JW, Cerione RA, Skiniotis G. Structures of the Rhodopsin-Transducin Complex: Insights into G-Protein Activation. Molecular Cell. PMID 31300275 DOI: 10.2210/Pdb6Oy9/Pdb |
0.653 |
|
| 2019 |
Latifkar A, Hur YH, Sanchez JC, Cerione RA, Antonyak MA. New insights into extracellular vesicle biogenesis and function. Journal of Cell Science. 132. PMID 31263077 DOI: 10.1242/Jcs.222406 |
0.802 |
|
| 2019 |
Gao Y, Erickson JW, Cerione RA, Ramachandran S. Reconstitution of the Rhodopsin-Transducin Complex into Lipid Nanodiscs. Methods in Molecular Biology (Clifton, N.J.). 2009: 317-324. PMID 31152414 DOI: 10.1007/978-1-4939-9532-5_24 |
0.459 |
|
| 2019 |
Gao Y, Erickson JW, Cerione RA, Ramachandran S. Purification of the Rhodopsin-Transducin Complex for Structural Studies. Methods in Molecular Biology (Clifton, N.J.). 2009: 307-315. PMID 31152413 DOI: 10.1007/978-1-4939-9532-5_23 |
0.49 |
|
| 2019 |
Schwager SC, Bordeleau F, Zhang J, Antonyak MA, Cerione RA, Reinhart-King C. Matrix stiffness regulates microvesicle-induced fibroblast activation. American Journal of Physiology. Cell Physiology. PMID 31017799 DOI: 10.1152/Ajpcell.00418.2018 |
0.415 |
|
| 2019 |
Latifkar A, Ling L, Hingorani A, Johansen E, Clement A, Zhang X, Hartman J, Fischbach C, Lin H, Cerione RA, Antonyak MA. Loss of Sirtuin 1 Alters the Secretome of Breast Cancer Cells by Impairing Lysosomal Integrity. Developmental Cell. PMID 30982660 DOI: 10.1016/J.Devcel.2019.03.011 |
0.797 |
|
| 2019 |
Antonyak MA, Lukey MJ, Cerione RA. Lipid-filled vesicles modulate macrophages. Science (New York, N.Y.). 363: 931-932. PMID 30819952 DOI: 10.1126/Science.Aaw6765 |
0.687 |
|
| 2018 |
Katt WP, Blobel NJ, Komarova S, Antonyak MA, Nakano I, Cerione RA. A small molecule regulator of tissue transglutaminase conformation inhibits the malignant phenotype of cancer cells. Oncotarget. 9: 34379-34397. PMID 30344949 DOI: 10.18632/Oncotarget.26193 |
0.424 |
|
| 2018 |
Latifkar A, Cerione RA, Antonyak MA. Probing the mechanisms of extracellular vesicle biogenesis and function in cancer. Biochemical Society Transactions. PMID 30301841 DOI: 10.1042/Bst20180523 |
0.807 |
|
| 2018 |
Milano SK, Wang C, Erickson J, Cerione RA, Ramachandran S. Gain-of-function screen of alpha transducin identifies an essential phenylalanine residue necessary for full effector activation. The Journal of Biological Chemistry. PMID 30266806 DOI: 10.1074/Jbc.Ra118.003746 |
0.301 |
|
| 2018 |
Lukey MJ, Katt WP, Cerione RA. Targeting Therapy Resistance: When Glutamine Catabolism Becomes Essential. Cancer Cell. 33: 795-797. PMID 29763620 DOI: 10.1016/J.Ccell.2018.04.009 |
0.744 |
|
| 2018 |
Katt WP, Antonyak MA, Cerione RA. The diamond anniversary of tissue transglutaminase: a protein of many talents. Drug Discovery Today. PMID 29362136 DOI: 10.1016/J.Drudis.2018.01.037 |
0.372 |
|
| 2018 |
Huang Q, Stalnecker C, Zhang C, McDermott LA, Iyer P, O'Neill J, Reimer S, Cerione RA, Katt WP. Characterization of the interactions of potent allosteric inhibitors with glutaminase C, a key enzyme in cancer cell glutamine metabolism. The Journal of Biological Chemistry. PMID 29317493 DOI: 10.1074/Jbc.M117.810101 |
0.426 |
|
| 2018 |
Latifkar A, Ling L, Zhang X, Fischbach C, Lin H, Cerione R, Antonyak M. Abstract 4506: Loss of SIRT1 alters the secretome of breast cancer cells by impairing lysosomal integrity Cancer Research. 78: 4506-4506. DOI: 10.1158/1538-7445.Am2018-4506 |
0.8 |
|
| 2018 |
Katt WP, Cerione RA. Abstract A156: Traditional chemotherapeutic agents as selective inhibitors of glutaminase isozymes Molecular Cancer Therapeutics. 17. DOI: 10.1158/1535-7163.Targ-17-A156 |
0.378 |
|
| 2017 |
Yoo SM, Cerione RA, Antonyak MA. The Arf-GAP and Protein Scaffold Cat1/Git1 as a Multifaceted Regulator of Cancer Progression. Small Gtpases. 0. PMID 28981399 DOI: 10.1080/21541248.2017.1362496 |
0.429 |
|
| 2017 |
Gao Y, Westfield G, Erickson JW, Cerione RA, Skiniotis G, Ramachandran S. Isolation and Structure-function Characterization of a Signaling-active Rhodopsin-G protein Complex. The Journal of Biological Chemistry. PMID 28655769 DOI: 10.1074/Jbc.M117.797100 |
0.657 |
|
| 2017 |
de Opakua AI, Parag-Sharma K, DiGiacomo V, Merino N, Leyme A, Marivin A, Villate M, Nguyen LT, de la Cruz-Morcillo MA, Blanco-Canosa JB, Ramachandran S, Baillie GS, Cerione RA, Blanco FJ, Garcia-Marcos M. Molecular mechanism of Gαi activation by non-GPCR proteins with a Gα-Binding and Activating motif. Nature Communications. 8: 15163. PMID 28516903 DOI: 10.1038/Ncomms15163 |
0.365 |
|
| 2017 |
Sullivan KE, Rojas K, Cerione RA, Nakano I, Wilson KF. The stem cell/cancer stem cell marker ALDH1A3 regulates the expression of the survival factor tissue transglutaminase, in mesenchymal glioma stem cells. Oncotarget. 8: 22325-22343. PMID 28423611 DOI: 10.18632/Oncotarget.16479 |
0.374 |
|
| 2017 |
Cluntun AA, Lukey MJ, Cerione RA, Locasale JW. Glutamine Metabolism in Cancer: Understanding the Heterogeneity. Trends in Cancer. 3: 169-180. PMID 28393116 DOI: 10.1016/J.Trecan.2017.01.005 |
0.787 |
|
| 2017 |
Feng Q, Zhang C, Lum D, Druso JE, Blank B, Wilson KF, Welm A, Antonyak MA, Cerione RA. A class of extracellular vesicles from breast cancer cells activates VEGF receptors and tumour angiogenesis. Nature Communications. 8: 14450. PMID 28205552 DOI: 10.1038/Ncomms14450 |
0.554 |
|
| 2017 |
Stalnecker CA, Erickson JW, Cerione RA. Conformational Changes in the Activation Loop of Mitochondrial Glutaminase C: A Direct Fluorescence Read-Out that Distinguishes the Binding of Allosteric Inhibitors from Activators. The Journal of Biological Chemistry. PMID 28196863 DOI: 10.1074/Jbc.M116.758219 |
0.383 |
|
| 2017 |
Katt WP, Lukey MJ, Cerione RA. A tale of two glutaminases: homologous enzymes with distinct roles in tumorigenesis. Future Medicinal Chemistry. PMID 28111979 DOI: 10.4155/Fmc-2016-0190 |
0.754 |
|
| 2017 |
French KC, Antonyak MA, Cerione RA. Extracellular vesicle docking at the cellular port: Extracellular vesicle binding and uptake. Seminars in Cell & Developmental Biology. PMID 28104520 DOI: 10.1016/J.Semcdb.2017.01.002 |
0.381 |
|
| 2017 |
Yoo SM, Latifkar A, Cerione RA, Antonyak MA. Cool-associated tyrosine phosphorylated protein-1 is required for the anchorage-independent growth of cervical carcinoma cells by binding paxillin and promoting AKT activation. The Journal of Biological Chemistry. PMID 28100775 DOI: 10.1074/Jbc.M116.769190 |
0.821 |
|
| 2017 |
Minata M, Alsheikh HA, Harada S, Peker D, Gillespie Y, Cerione R, Tannous B, Nakano I, Samant R, Lu S, Yamaguchi S. TMIC-07. HIGH ALDEHYDE DEHYDROGENASE ACTIVITY IDENTIFIES BRAIN METASTASIS-INITIATING CELLS IN BREAST CANCER Neuro-Oncology. 19: vi244-vi244. DOI: 10.1093/Neuonc/Nox168.997 |
0.345 |
|
| 2017 |
Alsheikh HA, Minata M, Yamaguchi S, Harada S, Peker D, Samant R, Tannous B, Bhat K, Cerione R, Zhang S, Nakano I. TMIC-31. MLK4 IS REQUIRED FOR METASTASIS INITIATION IN THE BRAIN Neuro-Oncology. 19: vi250-vi250. DOI: 10.1093/Neuonc/Nox168.1020 |
0.373 |
|
| 2016 |
Stalnecker CA, Cluntun AA, Cerione RA. Balancing redox stress: anchorage-independent growth requires reductive carboxylation. Translational Cancer Research. 5: S433-S437. PMID 28232903 DOI: 10.21037/Tcr.2016.09.02 |
0.759 |
|
| 2016 |
Lukey MJ, Katt WP, Cerione RA. Targeting amino acid metabolism for cancer therapy. Drug Discovery Today. PMID 27988359 DOI: 10.1016/J.Drudis.2016.12.003 |
0.744 |
|
| 2016 |
Kreger BT, Johansen ER, Cerione RA, Antonyak MA. The Enrichment of Survivin in Exosomes from Breast Cancer Cells Treated with Paclitaxel Promotes Cell Survival and Chemoresistance. Cancers. 8. PMID 27941677 DOI: 10.3390/Cancers8120111 |
0.412 |
|
| 2016 |
Song YH, Warncke C, Choi SJ, Choi S, Chiou AE, Ling L, Liu HY, Daniel S, Antonyak MA, Cerione RA, Fischbach C. Breast cancer-derived extracellular vesicles stimulate myofibroblast differentiation and pro-angiogenic behavior of adipose stem cells. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 27913195 DOI: 10.1016/J.Matbio.2016.11.008 |
0.386 |
|
| 2016 |
Antonyak MA, Cerione RA. The distinct traits of extracellular vesicles generated by transformed cells. Small Gtpases. 0. PMID 27754746 DOI: 10.1080/21541248.2016.1249044 |
0.429 |
|
| 2016 |
Bussche L, Rauner G, Antonyak M, Syracuse B, McDowell M, Brown AM, Cerione RA, Van de Walle GR. Microvesicle-Mediated Wnt/b-catenin Signaling Promotes Interspecies Mammary Stem/Progenitor Cell Growth. The Journal of Biological Chemistry. PMID 27733685 DOI: 10.1074/Jbc.M116.726117 |
0.336 |
|
| 2016 |
Li Y, Erickson JW, Stalnecker CA, Katt WP, Huang Q, Cerione RA, Ramachandran S. Mechanistic Basis of Glutaminase Activation: A Key Enzyme that Promotes Glutamine Metabolism in Cancer Cells. The Journal of Biological Chemistry. PMID 27542409 DOI: 10.1074/Jbc.M116.720268 |
0.395 |
|
| 2016 |
Kreger BT, Dougherty AL, Greene KS, Cerione RA, Antonyak MA. Microvesicle Cargo and Function Changes Upon the Induction of Cellular Transformation. The Journal of Biological Chemistry. PMID 27440046 DOI: 10.1074/Jbc.M116.725705 |
0.441 |
|
| 2016 |
Zhang X, Khan S, Jiang H, Antonyak MA, Chen X, Spiegelman NA, Shrimp JH, Cerione RA, Lin H. Identifying the functional contribution of the defatty-acylase activity of SIRT6. Nature Chemical Biology. PMID 27322069 DOI: 10.1038/Nchembio.2106 |
0.606 |
|
| 2016 |
Desrochers LM, Bordeleau F, Reinhart-King CA, Cerione RA, Antonyak MA. Microvesicles provide a mechanism for intercellular communication by embryonic stem cells during embryo implantation. Nature Communications. 7: 11958. PMID 27302045 DOI: 10.1038/Ncomms11958 |
0.325 |
|
| 2016 |
Desrochers LM, Antonyak MA, Cerione RA. Extracellular Vesicles: Satellites of Information Transfer in Cancer and Stem Cell Biology. Developmental Cell. 37: 301-9. PMID 27219060 DOI: 10.1016/J.Devcel.2016.04.019 |
0.393 |
|
| 2016 |
Lukey MJ, Greene KS, Erickson JW, Wilson KF, Cerione RA. The oncogenic transcription factor c-Jun regulates glutaminase expression and sensitizes cells to glutaminase-targeted therapy. Nature Communications. 7: 11321. PMID 27089238 DOI: 10.1038/Ncomms11321 |
0.769 |
|
| 2016 |
Hall J, Prabhakar S, Balaj L, Lai CP, Cerione RA, Breakefield XO. Delivery of Therapeutic Proteins via Extracellular Vesicles: Review and Potential Treatments for Parkinson's Disease, Glioma, and Schwannoma. Cellular and Molecular Neurobiology. PMID 27017608 DOI: 10.1007/S10571-015-0309-0 |
0.362 |
|
| 2016 |
McDermott LA, Iyer P, Vernetti L, Rimer S, Sun J, Boby M, Yang T, Fioravanti M, O'Neill J, Wang L, Drakes D, Katt W, Huang Q, Cerione R. Design and evaluation of novel glutaminase inhibitors. Bioorganic & Medicinal Chemistry. PMID 26988803 DOI: 10.1016/J.Bmc.2016.03.009 |
0.326 |
|
| 2016 |
Druso JE, Endo M, Lin MJ, Peng X, Antonyak MA, Meller S, Cerione RA. An Essential Role for Cdc42 in the Functioning of the Adult Mammary Gland. The Journal of Biological Chemistry. PMID 26912661 DOI: 10.1074/Jbc.M115.694349 |
0.36 |
|
| 2016 |
Singh G, Zhang J, Ma Y, Cerione RA, Antonyak MA. The Different Conformational States of Tissue Transglutaminase Have Opposing Affects on Cell Viability. The Journal of Biological Chemistry. PMID 26893378 DOI: 10.1074/Jbc.M115.699108 |
0.383 |
|
| 2016 |
Lukey MJ, Cerione RA. The regulation of cancer cell glutamine metabolism Translational Cancer Research. 5. DOI: 10.21037/10459 |
0.77 |
|
| 2015 |
Bordeleau F, Chan B, Antonyak MA, Lampi MC, Cerione RA, Reinhart-King CA. Microvesicles released from tumor cells disrupt epithelial cell morphology and contractility. Journal of Biomechanics. PMID 26477404 DOI: 10.1016/J.Jbiomech.2015.10.003 |
0.381 |
|
| 2015 |
Choi HW, Tian M, Song F, Venereau E, Preti A, Park SW, Hamilton K, Swapna GV, Manohar M, Moreau M, Agresti A, Gorzanelli A, De Marchis F, Wang H, Antonyak M, ... ... Cerione RA, et al. Aspirin's Active Metabolite Salicylic Acid Targets High Mobility Group Box 1 to Modulate Inflammatory Responses. Molecular Medicine (Cambridge, Mass.). PMID 26101955 DOI: 10.2119/Molmed.2015.00148 |
0.354 |
|
| 2015 |
Antonyak MA, Cerione RA. Emerging picture of the distinct traits and functions of microvesicles and exosomes. Proceedings of the National Academy of Sciences of the United States of America. 112: 3589-90. PMID 25762069 DOI: 10.1073/Pnas.1502590112 |
0.396 |
|
| 2015 |
Stalnecker CA, Ulrich SM, Li Y, Ramachandran S, McBrayer MK, DeBerardinis RJ, Cerione RA, Erickson JW. Mechanism by which a recently discovered allosteric inhibitor blocks glutamine metabolism in transformed cells. Proceedings of the National Academy of Sciences of the United States of America. 112: 394-9. PMID 25548170 DOI: 10.1073/Pnas.1414056112 |
0.813 |
|
| 2015 |
Katt WP, Antonyak MA, Cerione RA. Simultaneously targeting tissue transglutaminase and kidney type glutaminase sensitizes cancer cells to acid toxicity and offers new opportunities for therapeutic intervention. Molecular Pharmaceutics. 12: 46-55. PMID 25426679 DOI: 10.1021/Mp500405H |
0.338 |
|
| 2015 |
Kreger BT, Antonyak M, Cerione R. Abstract LB-025: Survivin is trafficked into cancer cell-derived exosomes via a microtubule-dependent mechanism Cancer Research. 75. DOI: 10.1158/1538-7445.Am2015-Lb-025 |
0.429 |
|
| 2014 |
Santana SM, Antonyak MA, Cerione RA, Kirby BJ. Cancerous epithelial cell lines shed extracellular vesicles with a bimodal size distribution that is sensitive to glutamine inhibition. Physical Biology. 11: 065001. PMID 25426818 DOI: 10.1088/1478-3975/11/6/065001 |
0.388 |
|
| 2014 |
Santana SM, Antonyak MA, Cerione RA, Kirby BJ. Microfluidic isolation of cancer-cell-derived microvesicles from hetergeneous extracellular shed vesicle populations. Biomedical Microdevices. 16: 869-77. PMID 25342569 DOI: 10.1007/S10544-014-9891-Z |
0.38 |
|
| 2014 |
Salamanca HH, Antonyak MA, Cerione RA, Shi H, Lis JT. Inhibiting heat shock factor 1 in human cancer cells with a potent RNA aptamer. Plos One. 9: e96330. PMID 24800749 DOI: 10.1371/Journal.Pone.0096330 |
0.42 |
|
| 2014 |
Lin MC, Rojas KS, Cerione RA, Wilson KF. Identification of mTORC2 as a necessary component of HRG/ErbB2-dependent cellular transformation. Molecular Cancer Research : McR. 12: 940-52. PMID 24615340 DOI: 10.1158/1541-7786.Mcr-13-0555 |
0.404 |
|
| 2014 |
Boroughs LK, Antonyak MA, Cerione RA. A novel mechanism by which tissue transglutaminase activates signaling events that promote cell survival. The Journal of Biological Chemistry. 289: 10115-25. PMID 24569994 DOI: 10.1074/jbc.M113.464693 |
0.318 |
|
| 2014 |
Erickson JW, Antonyak MA, Fuji R, Cerione RA. Rho GTPases in cancer Ras Superfamily Small G Proteins: Biology and Mechanisms 1: General Features, Signaling. 421-438. DOI: 10.1007/978-3-7091-1806-1_18 |
0.678 |
|
| 2013 |
Bryant KL, Antonyak MA, Cerione RA, Baird B, Holowka D. Mutations in the polybasic juxtamembrane sequence of both plasma membrane- and endoplasmic reticulum-localized epidermal growth factor receptors confer ligand-independent cell transformation. The Journal of Biological Chemistry. 288: 34930-42. PMID 24142702 DOI: 10.1074/Jbc.M113.513333 |
0.692 |
|
| 2013 |
Møller M, Nielsen SS, Ramachandran S, Li Y, Li Y, Tria G, Streicher W, Petoukhov MV, Cerione RA, Gillilan RE, Vestergaard B. Small angle X-ray scattering studies of mitochondrial glutaminase C reveal extended flexible regions, and link oligomeric state with enzyme activity. Plos One. 8: e74783. PMID 24098668 DOI: 10.1371/Journal.Pone.0074783 |
0.335 |
|
| 2013 |
Lukey MJ, Wilson KF, Cerione RA. Therapeutic strategies impacting cancer cell glutamine metabolism. Future Medicinal Chemistry. 5: 1685-700. PMID 24047273 DOI: 10.4155/Fmc.13.130 |
0.747 |
|
| 2013 |
Jin Y, Liu Y, Lin Q, Li J, Druso JE, Antonyak MA, Meininger CJ, Zhang SL, Dostal DE, Guan JL, Cerione RA, Peng X. Deletion of Cdc42 enhances ADAM17-mediated vascular endothelial growth factor receptor 2 shedding and impairs vascular endothelial cell survival and vasculogenesis. Molecular and Cellular Biology. 33: 4181-97. PMID 23979594 DOI: 10.1128/Mcb.00650-13 |
0.331 |
|
| 2013 |
Zhou Y, Johnson JL, Cerione RA, Erickson JW. Prenylation and membrane localization of Cdc42 are essential for activation by DOCK7. Biochemistry. 52: 4354-63. PMID 23718289 DOI: 10.1021/Bi301688G |
0.799 |
|
| 2013 |
Freisinger T, Klünder B, Johnson J, Müller N, Pichler G, Beck G, Costanzo M, Boone C, Cerione RA, Frey E, Wedlich-Söldner R. Establishment of a robust single axis of cell polarity by coupling multiple positive feedback loops. Nature Communications. 4: 1807. PMID 23651995 DOI: 10.1038/Ncomms2795 |
0.321 |
|
| 2013 |
Wilson KF, Erickson JW, Antonyak MA, Cerione RA. Rho GTPases and their roles in cancer metabolism. Trends in Molecular Medicine. 19: 74-82. PMID 23219172 DOI: 10.1016/j.molmed.2012.10.011 |
0.301 |
|
| 2012 |
Antonyak MA, Wilson KF, Cerione RA. R(h)oads to microvesicles. Small Gtpases. 3: 219-24. PMID 22906997 DOI: 10.4161/Sgtp.20755 |
0.446 |
|
| 2012 |
Yoo SM, Antonyak MA, Cerione RA. The adaptor protein and Arf GTPase-activating protein Cat-1/Git-1 is required for cellular transformation. The Journal of Biological Chemistry. 287: 31462-70. PMID 22807447 DOI: 10.1074/Jbc.M112.353615 |
0.447 |
|
| 2012 |
Zhou Y, Zhang H, He B, Du J, Lin H, Cerione RA, Hao Q. The bicyclic intermediate structure provides insights into the desuccinylation mechanism of human sirtuin 5 (SIRT5). The Journal of Biological Chemistry. 287: 28307-14. PMID 22767592 DOI: 10.1074/Jbc.M112.384511 |
0.775 |
|
| 2012 |
Milano SK, Kwon W, Pereira R, Antonyak MA, Cerione RA. Characterization of a novel activated Ran GTPase mutant and its ability to induce cellular transformation. The Journal of Biological Chemistry. 287: 24955-66. PMID 22679017 DOI: 10.1074/Jbc.M111.306514 |
0.435 |
|
| 2012 |
Katt WP, Ramachandran S, Erickson JW, Cerione RA. Dibenzophenanthridines as inhibitors of glutaminase C and cancer cell proliferation. Molecular Cancer Therapeutics. 11: 1269-78. PMID 22496480 DOI: 10.1158/1535-7163.Mct-11-0942 |
0.347 |
|
| 2012 |
Singh G, Ramachandran S, Cerione RA. A constitutively active Gα subunit provides insights into the mechanism of G protein activation. Biochemistry. 51: 3232-40. PMID 22448927 DOI: 10.1021/Bi3001984 |
0.342 |
|
| 2012 |
Li B, Antonyak MA, Zhang J, Cerione RA. RhoA triggers a specific signaling pathway that generates transforming microvesicles in cancer cells. Oncogene. 31: 4740-9. PMID 22266864 DOI: 10.1038/onc.2011.636 |
0.317 |
|
| 2012 |
Li Y, Ramachandran S, Cerione RA. Investigating the Mechanism of Activation and Inhibition of the Phosphate Dependent Mitochondrial Glutaminase Biophysical Journal. 102: 620a-621a. DOI: 10.1016/J.Bpj.2011.11.3381 |
0.386 |
|
| 2011 |
Du J, Zhou Y, Su X, Yu JJ, Khan S, Jiang H, Kim J, Woo J, Kim JH, Choi BH, He B, Chen W, Zhang S, Cerione RA, Auwerx J, et al. Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase. Science (New York, N.Y.). 334: 806-9. PMID 22076378 DOI: 10.1126/Science.1207861 |
0.791 |
|
| 2011 |
Boroughs LK, Antonyak MA, Johnson JL, Cerione RA. A unique role for heat shock protein 70 and its binding partner tissue transglutaminase in cancer cell migration. The Journal of Biological Chemistry. 286: 37094-107. PMID 21896482 DOI: 10.1074/Jbc.M111.242438 |
0.428 |
|
| 2011 |
Antonyak MA, Li B, Boroughs LK, Johnson JL, Druso JE, Bryant KL, Holowka DA, Cerione RA. Cancer cell-derived microvesicles induce transformation by transferring tissue transglutaminase and fibronectin to recipient cells. Proceedings of the National Academy of Sciences of the United States of America. 108: 4852-7. PMID 21368175 DOI: 10.1073/pnas.1017667108 |
0.612 |
|
| 2011 |
Ramachandran S, Cerione RA. A dominant-negative Galpha mutant that traps a stable rhodopsin-Galpha-GTP-betagamma complex. The Journal of Biological Chemistry. 286: 12702-11. PMID 21285355 DOI: 10.1074/Jbc.M110.166538 |
0.322 |
|
| 2011 |
Englich U, Kriksunov IA, Cerione RA, Cook MJ, Gillilan R, Gruner SM, Huang Q, Kim CU, Miller W, Nielsen S, Schuller D, Smith S, Szebenyi DM. Microcrystallography, high-pressure cryocooling and BioSAXS at MacCHESS. Journal of Synchrotron Radiation. 18: 70-3. PMID 21169696 DOI: 10.1107/S0909049510036010 |
0.511 |
|
| 2011 |
Wu X, Ramachandran S, Lin MC, Cerione RA, Erickson JW. A minimal Rac activation domain in the unconventional guanine nucleotide exchange factor Dock180. Biochemistry. 50: 1070-80. PMID 21033699 DOI: 10.1021/Bi100971Y |
0.307 |
|
| 2011 |
Cerione RA. Abstract PL08-04: New ways to impact glutamine metabolism in cancer. Molecular Cancer Therapeutics. 10. DOI: 10.1158/1535-7163.Targ-11-Pl08-04 |
0.458 |
|
| 2010 |
Dias SM, Cerione RA, Wilson KF. Unloading RNAs in the cytoplasm: an "importin" task. Nucleus (Austin, Tex.). 1: 139-43. PMID 21326945 DOI: 10.4161/Nucl.1.2.10919 |
0.312 |
|
| 2010 |
Wang JB, Erickson JW, Fuji R, Ramachandran S, Gao P, Dinavahi R, Wilson KF, Ambrosio AL, Dias SM, Dang CV, Cerione RA. Targeting mitochondrial glutaminase activity inhibits oncogenic transformation. Cancer Cell. 18: 207-19. PMID 20832749 DOI: 10.1016/J.Ccr.2010.08.009 |
0.724 |
|
| 2010 |
Feng Q, Baird D, Yoo S, Antonyak M, Cerione RA. Phosphorylation of the cool-1/beta-Pix protein serves as a regulatory signal for the migration and invasive activity of Src-transformed cells. The Journal of Biological Chemistry. 285: 18806-16. PMID 20375009 DOI: 10.1074/Jbc.M109.098079 |
0.593 |
|
| 2010 |
Li B, Antonyak MA, Druso JE, Cheng L, Nikitin AY, Cerione RA. EGF potentiated oncogenesis requires a tissue transglutaminase-dependent signaling pathway leading to Src activation. Proceedings of the National Academy of Sciences of the United States of America. 107: 1408-13. PMID 20080707 DOI: 10.1073/Pnas.0907907107 |
0.445 |
|
| 2010 |
Ly TK, Wang J, Pereira R, Rojas KS, Peng X, Feng Q, Cerione RA, Wilson KF. Activation of the Ran GTPase is subject to growth factor regulation and can give rise to cellular transformation. The Journal of Biological Chemistry. 285: 5815-26. PMID 20028979 DOI: 10.1074/Jbc.M109.071886 |
0.81 |
|
| 2010 |
Wang JB, Erickson JW, Fuji R, Ramachandran S, Gao P, Dinavahi R, Wilson KF, Ambrosio ALB, Dias SMG, Dang CV, Cerione RA. Targeting mitochondrial glutaminase activity inhibits oncogenic transformation Cancer Cell. 18: 397. DOI: 10.1016/j.ccr.2010.10.011 |
0.663 |
|
| 2010 |
Feng Q, Cerione RA. Cdc42 and its cellular functions Handbook of Cell Signaling, 2/E. 2: 1785-1794. DOI: 10.1016/B978-0-12-374145-5.00218-7 |
0.408 |
|
| 2009 |
Antonyak MA, Cerione RA. Ras and the FAK paradox. Molecular Cell. 35: 141-2. PMID 19647511 DOI: 10.1016/J.Molcel.2009.07.005 |
0.321 |
|
| 2009 |
Johnson JL, Erickson JW, Cerione RA. New insights into how the Rho guanine nucleotide dissociation inhibitor regulates the interaction of Cdc42 with membranes. The Journal of Biological Chemistry. 284: 23860-71. PMID 19581296 DOI: 10.1074/Jbc.M109.031815 |
0.362 |
|
| 2009 |
Antonyak MA, Li B, Regan AD, Feng Q, Dusaban SS, Cerione RA. Tissue transglutaminase is an essential participant in the epidermal growth factor-stimulated signaling pathway leading to cancer cell migration and invasion. The Journal of Biological Chemistry. 284: 17914-25. PMID 19403524 DOI: 10.1074/Jbc.M109.013037 |
0.601 |
|
| 2009 |
Johnson JL, Erickson JW, Cerione RA. Development of a FRET-based Reconstitution Assay to Probe the Interaction Between the Rho Family GTPases and Defined Synthetic Lipid Membranes Biophysical Journal. 96: 613a. DOI: 10.1016/J.Bpj.2008.12.3240 |
0.345 |
|
| 2008 |
Peng X, Wu X, Druso JE, Wei H, Park AY, Kraus MS, Alcaraz A, Chen J, Chien S, Cerione RA, Guan JL. Cardiac developmental defects and eccentric right ventricular hypertrophy in cardiomyocyte focal adhesion kinase (FAK) conditional knockout mice. Proceedings of the National Academy of Sciences of the United States of America. 105: 6638-43. PMID 18448675 DOI: 10.1073/Pnas.0802319105 |
0.681 |
|
| 2008 |
Phillips MJ, Calero G, Chan B, Ramachandran S, Cerione RA. Effector proteins exert an important influence on the signaling-active state of the small GTPase Cdc42. The Journal of Biological Chemistry. 283: 14153-64. PMID 18348980 DOI: 10.1074/Jbc.M706271200 |
0.38 |
|
| 2008 |
DeRegis CJ, Rahl PB, Hoffman GR, Cerione RA, Collins RN. Mutational analysis of betaCOP (Sec26p) identifies an appendage domain critical for function. Bmc Cell Biology. 9: 3. PMID 18211691 DOI: 10.1186/1471-2121-9-3 |
0.587 |
|
| 2008 |
Erickson JW, Cerione RA. A new tool for G protein analysis. Acs Chemical Biology. 3: 24-6. PMID 18205289 DOI: 10.1021/Cb700239D |
0.345 |
|
| 2007 |
Datta S, Antonyak MA, Cerione RA. GTP-binding-defective forms of tissue transglutaminase trigger cell death. Biochemistry. 46: 14819-29. PMID 18052077 DOI: 10.1021/Bi701422H |
0.377 |
|
| 2007 |
Casey FP, Baird D, Feng Q, Gutenkunst RN, Waterfall JJ, Myers CR, Brown KS, Cerione RA, Sethna JP. Optimal experimental design in an epidermal growth factor receptor signalling and down-regulation model. Iet Systems Biology. 1: 190-202. PMID 17591178 DOI: 10.1049/Iet-Syb:20060065 |
0.515 |
|
| 2007 |
Dias SM, Cerione RA. X-ray crystal structures reveal two activated states for RhoC. Biochemistry. 46: 6547-58. PMID 17497936 DOI: 10.1021/Bi700035P |
0.378 |
|
| 2006 |
Antonyak MA, Jansen JM, Miller AM, Ly TK, Endo M, Cerione RA. Two isoforms of tissue transglutaminase mediate opposing cellular fates. Proceedings of the National Academy of Sciences of the United States of America. 103: 18609-14. PMID 17116873 DOI: 10.1073/Pnas.0604844103 |
0.79 |
|
| 2006 |
Datta S, Antonyak MA, Cerione RA. Importance of Ca(2+)-dependent transamidation activity in the protection afforded by tissue transglutaminase against doxorubicin-induced apoptosis. Biochemistry. 45: 13163-74. PMID 17073438 DOI: 10.1021/Bi0606795 |
0.337 |
|
| 2006 |
Lin Q, Yang W, Baird D, Feng Q, Cerione RA. Identification of a DOCK180-related guanine nucleotide exchange factor that is capable of mediating a positive feedback activation of Cdc42. The Journal of Biological Chemistry. 281: 35253-62. PMID 16968698 DOI: 10.1074/Jbc.M606248200 |
0.575 |
|
| 2006 |
Ramachandran S, Cerione RA. How GPCRs hit the switch. Nature Structural & Molecular Biology. 13: 756-7. PMID 16955094 DOI: 10.1038/Nsmb0906-756 |
0.325 |
|
| 2006 |
Feng Q, Baird D, Peng X, Wang J, Ly T, Guan JL, Cerione RA. Cool-1 functions as an essential regulatory node for EGF receptor- and Src-mediated cell growth. Nature Cell Biology. 8: 945-56. PMID 16892055 DOI: 10.1038/Ncb1453 |
0.789 |
|
| 2006 |
Fidyk N, Wang JB, Cerione RA. Influencing cellular transformation by modulating the rates of GTP hydrolysis by Cdc42. Biochemistry. 45: 7750-62. PMID 16784226 DOI: 10.1021/Bi060365H |
0.808 |
|
| 2006 |
Wakshlag JJ, Antonyak MA, Boehm JE, Boehm K, Cerione RA. Effects of tissue transglutaminase on beta -amyloid1-42-induced apoptosis. The Protein Journal. 25: 83-94. PMID 16721663 DOI: 10.1007/S10930-006-0009-1 |
0.58 |
|
| 2006 |
Wakshlag JJ, McNeill CJ, Antonyak MA, Boehm JE, Fuji R, Balkman CE, Zgola M, Cerione RA, Page RL. Expression and activity of transglutaminase II in spontaneous tumours of dogs and cats. Journal of Comparative Pathology. 134: 202-10. PMID 16615935 DOI: 10.1016/J.Jcpa.2005.11.001 |
0.755 |
|
| 2006 |
Lin Q, Yang W, Cerione RA. Measurement of epidermal growth factor receptor turnover and effects of Cdc42. Methods in Enzymology. 406: 614-25. PMID 16472692 DOI: 10.1016/S0076-6879(06)06048-4 |
0.354 |
|
| 2006 |
Baird D, Feng Q, Cerione RA. Biochemical characterization of the Cool (Cloned-out-of-Library)/Pix (Pak-interactive exchange factor) proteins. Methods in Enzymology. 406: 58-69. PMID 16472649 DOI: 10.1016/S0076-6879(06)06005-8 |
0.56 |
|
| 2006 |
Majumdar S, Ramachandran S, Cerione RA. New insights into the role of conserved, essential residues in the GTP binding/GTP hydrolytic cycle of large G proteins. The Journal of Biological Chemistry. 281: 9219-26. PMID 16469737 DOI: 10.1074/Jbc.M513837200 |
0.577 |
|
| 2005 |
Smith WJ, Hamel B, Yohe ME, Sondek J, Cerione RA, Snyder JT. A Cdc42 mutant specifically activated by intersectin. Biochemistry. 44: 13282-90. PMID 16201754 DOI: 10.1021/Bi050591B |
0.39 |
|
| 2005 |
Pereira R, Cerione RA. A switch 3 point mutation in the alpha subunit of transducin yields a unique dominant-negative inhibitor. The Journal of Biological Chemistry. 280: 35696-703. PMID 16103122 DOI: 10.1074/Jbc.M504935200 |
0.33 |
|
| 2005 |
Wang JB, Wu WJ, Cerione RA. Cdc42 and Ras cooperate to mediate cellular transformation by intersectin-L. The Journal of Biological Chemistry. 280: 22883-91. PMID 15824104 DOI: 10.1074/Jbc.M414375200 |
0.383 |
|
| 2005 |
Baird D, Feng Q, Cerione RA. The Cool-2/alpha-Pix protein mediates a Cdc42-Rac signaling cascade. Current Biology : Cb. 15: 1-10. PMID 15649357 DOI: 10.1016/J.Cub.2004.12.040 |
0.574 |
|
| 2004 |
Brown KS, Hill CC, Calero GA, Myers CR, Lee KH, Sethna JP, Cerione RA. The statistical mechanics of complex signaling networks: nerve growth factor signaling. Physical Biology. 1: 184-95. PMID 16204838 DOI: 10.1088/1478-3967/1/3/006 |
0.311 |
|
| 2004 |
Feng Q, Baird D, Cerione RA. Novel regulatory mechanisms for the Dbl family guanine nucleotide exchange factor Cool-2/alpha-Pix. The Embo Journal. 23: 3492-504. PMID 15306850 DOI: 10.1038/Sj.Emboj.7600331 |
0.558 |
|
| 2004 |
Antonyak MA, Miller AM, Jansen JM, Boehm JE, Balkman CE, Wakshlag JJ, Page RL, Cerione RA. Augmentation of tissue transglutaminase expression and activation by epidermal growth factor inhibit doxorubicin-induced apoptosis in human breast cancer cells. The Journal of Biological Chemistry. 279: 41461-7. PMID 15272014 DOI: 10.1074/Jbc.M404976200 |
0.661 |
|
| 2004 |
Majumdar S, Ramachandran S, Cerione RA. Perturbing the linker regions of the alpha-subunit of transducin: a new class of constitutively active GTP-binding proteins. The Journal of Biological Chemistry. 279: 40137-45. PMID 15271992 DOI: 10.1074/Jbc.M405420200 |
0.548 |
|
| 2004 |
Ramachandran S, Cerione RA. Stabilization of an intermediate activation state for transducin by a fluorescent GTP analogue. Biochemistry. 43: 8778-86. PMID 15236586 DOI: 10.1021/Bi0362774 |
0.308 |
|
| 2004 |
Yang W, Jansen JM, Lin Q, Canova S, Cerione RA, Childress C. Interaction of activated Cdc42-associated tyrosine kinase ACK2 with HSP90. The Biochemical Journal. 382: 199-204. PMID 15144235 DOI: 10.1042/Bj20040623 |
0.369 |
|
| 2004 |
Fortier LA, Deak MM, Semevolos SA, Cerione RA. Insulin-like growth factor-I diminishes the activation status and expression of the small GTPase Cdc42 in articular chondrocytes. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 22: 436-45. PMID 15013107 DOI: 10.1016/J.Orthres.2003.08.021 |
0.358 |
|
| 2004 |
Cerione RA. Cdc42: new roads to travel. Trends in Cell Biology. 14: 127-32. PMID 15003621 DOI: 10.1016/J.Tcb.2004.01.008 |
0.378 |
|
| 2004 |
Erickson JW, Cerione RA. Structural elements, mechanism, and evolutionary convergence of Rho protein-guanine nucleotide exchange factor complexes. Biochemistry. 43: 837-42. PMID 14744125 DOI: 10.1021/Bi036026V |
0.384 |
|
| 2003 |
Hoffman GR, Rahl PB, Collins RN, Cerione RA. Conserved structural motifs in intracellular trafficking pathways: structure of the gammaCOP appendage domain. Molecular Cell. 12: 615-25. PMID 14527408 DOI: 10.1016/J.Molcel.2003.08.002 |
0.588 |
|
| 2003 |
Tu S, Wu WJ, Wang J, Cerione RA. Epidermal growth factor-dependent regulation of Cdc42 is mediated by the Src tyrosine kinase. The Journal of Biological Chemistry. 278: 49293-300. PMID 14506284 DOI: 10.1074/Jbc.M307021200 |
0.646 |
|
| 2003 |
Wu WJ, Tu S, Cerione RA. Activated Cdc42 sequesters c-Cbl and prevents EGF receptor degradation. Cell. 114: 715-25. PMID 14505571 DOI: 10.1016/S0092-8674(03)00688-3 |
0.682 |
|
| 2003 |
Lin Q, Fuji RN, Yang W, Cerione RA. RhoGDI is required for Cdc42-mediated cellular transformation. Current Biology : Cb. 13: 1469-79. PMID 12956948 DOI: 10.1016/S0960-9822(03)00613-4 |
0.756 |
|
| 2003 |
Flanders JA, Feng Q, Bagrodia S, Laux MT, Singavarapu A, Cerione RA. The Cbl proteins are binding partners for the Cool/Pix family of p21-activated kinase-binding proteins. Febs Letters. 550: 119-23. PMID 12935897 DOI: 10.1016/S0014-5793(03)00853-6 |
0.56 |
|
| 2003 |
Antonyak MA, McNeill CJ, Wakshlag JJ, Boehm JE, Cerione RA. Activation of the Ras-ERK pathway inhibits retinoic acid-induced stimulation of tissue transglutaminase expression in NIH3T3 cells. The Journal of Biological Chemistry. 278: 15859-66. PMID 12604597 DOI: 10.1074/Jbc.M300037200 |
0.618 |
|
| 2002 |
Fidyk NJ, Cerione RA. Understanding the catalytic mechanism of GTPase-activating proteins: demonstration of the importance of switch domain stabilization in the stimulation of GTP hydrolysis. Biochemistry. 41: 15644-53. PMID 12501193 DOI: 10.1021/Bi026413P |
0.802 |
|
| 2002 |
Osman MA, Konopka JB, Cerione RA. Iqg1p links spatial and secretion landmarks to polarity and cytokinesis. The Journal of Cell Biology. 159: 601-11. PMID 12446742 DOI: 10.1083/Jcb.200205084 |
0.308 |
|
| 2002 |
Calero G, Wilson KF, Ly T, Rios-Steiner JL, Clardy JC, Cerione RA. Structural basis of m7GpppG binding to the nuclear cap-binding protein complex. Nature Structural Biology. 9: 912-7. PMID 12434151 DOI: 10.1038/Nsb874 |
0.779 |
|
| 2002 |
Tu SS, Wu WJ, Yang W, Nolbant P, Hahn K, Cerione RA. Antiapoptotic Cdc42 mutants are potent activators of cellular transformation. Biochemistry. 41: 12350-8. PMID 12369824 DOI: 10.1021/Bi026167H |
0.671 |
|
| 2002 |
Smith WJ, Cerione RA. Crystallization and preliminary crystallographic analysis of the ezrin FERM domain. Acta Crystallographica. Section D, Biological Crystallography. 58: 1359-61. PMID 12136155 DOI: 10.1107/S0907444902010004 |
0.309 |
|
| 2002 |
Daniel S, Noda M, Cerione RA, Sharp GW. A link between Cdc42 and syntaxin is involved in mastoparan-stimulated insulin release. Biochemistry. 41: 9663-71. PMID 12135388 DOI: 10.1021/Bi025604P |
0.369 |
|
| 2002 |
Hoffman GR, Cerione RA. Signaling to the Rho GTPases: networking with the DH domain. Febs Letters. 513: 85-91. PMID 11911885 DOI: 10.1016/S0014-5793(01)03310-5 |
0.596 |
|
| 2002 |
Liu S, Cerione RA, Clardy J. Structural basis for the guanine nucleotide-binding activity of tissue transglutaminase and its regulation of transamidation activity. Proceedings of the National Academy of Sciences of the United States of America. 99: 2743-7. PMID 11867708 DOI: 10.1073/Pnas.042454899 |
0.363 |
|
| 2002 |
Antonyak MA, Boehm JE, Cerione RA. Phosphoinositide 3-kinase activity is required for retinoic acid-induced expression and activation of the tissue transglutaminase. The Journal of Biological Chemistry. 277: 14712-6. PMID 11854287 DOI: 10.1074/Jbc.M112259200 |
0.373 |
|
| 2002 |
Lin Q, Lo CG, Cerione RA, Yang W. The Cdc42 target ACK2 interacts with sorting nexin 9 (SH3PX1) to regulate epidermal growth factor receptor degradation. The Journal of Biological Chemistry. 277: 10134-8. PMID 11799118 DOI: 10.1074/Jbc.M110329200 |
0.409 |
|
| 2002 |
Feng Q, Albeck JG, Cerione RA, Yang W. Regulation of the Cool/Pix proteins: key binding partners of the Cdc42/Rac targets, the p21-activated kinases. The Journal of Biological Chemistry. 277: 5644-50. PMID 11741931 DOI: 10.1074/Jbc.M107704200 |
0.558 |
|
| 2001 |
Yang W, Lin Q, Zhao J, Guan JL, Cerione RA. The nonreceptor tyrosine kinase ACK2, a specific target for Cdc42 and a negative regulator of cell growth and focal adhesion complexes. The Journal of Biological Chemistry. 276: 43987-93. PMID 11535592 DOI: 10.1074/Jbc.M104819200 |
0.385 |
|
| 2001 |
Yang W, Lo CG, Dispenza T, Cerione RA. The Cdc42 target ACK2 directly interacts with clathrin and influences clathrin assembly. The Journal of Biological Chemistry. 276: 17468-73. PMID 11278777 DOI: 10.1074/Jbc.M010893200 |
0.422 |
|
| 2001 |
Tu S, Cerione RA. Cdc42 is a substrate for caspases and influences Fas-induced apoptosis. The Journal of Biological Chemistry. 276: 19656-63. PMID 11278572 DOI: 10.1074/Jbc.M009838200 |
0.639 |
|
| 2001 |
Erickson JW, Cerione RA. Multiple roles for Cdc42 in cell regulation. Current Opinion in Cell Biology. 13: 153-7. PMID 11248548 DOI: 10.1016/S0955-0674(00)00192-7 |
0.359 |
|
| 2001 |
Hoffman GR, Cerione RA. Rac inserts its way into the immune response. Nature Immunology. 2: 194-6. PMID 11224514 DOI: 10.1038/85240 |
0.593 |
|
| 2001 |
Hong-Geller E, Holowka D, Siraganian RP, Baird B, Cerione RA. Activated Cdc42/Rac reconstitutes Fcepsilon RI-mediated Ca2+ mobilization and degranulation in mutant RBL mast cells. Proceedings of the National Academy of Sciences of the United States of America. 98: 1154-9. PMID 11158610 DOI: 10.1073/Pnas.98.3.1154 |
0.702 |
|
| 2000 |
Wilson KF, Wu WJ, Cerione RA. Cdc42 stimulates RNA splicing via the S6 kinase and a novel S6 kinase target, the nuclear cap-binding complex. The Journal of Biological Chemistry. 275: 37307-10. PMID 10973943 DOI: 10.1074/Jbc.C000482200 |
0.381 |
|
| 2000 |
Hoffman GR, Cerione RA. Flipping the switch: the structural basis for signaling through the CRIB motif. Cell. 102: 403-6. PMID 10966102 DOI: 10.1016/S0092-8674(00)00045-3 |
0.55 |
|
| 2000 |
Wu WJ, Erickson JW, Lin R, Cerione RA. The gamma-subunit of the coatomer complex binds Cdc42 to mediate transformation. Nature. 405: 800-4. PMID 10866202 DOI: 10.1038/35015585 |
0.419 |
|
| 2000 |
Hoffman GR, Nassar N, Cerione RA. Structure of the Rho family GTP-binding protein Cdc42 in complex with the multifunctional regulator RhoGDI. Cell. 100: 345-56. PMID 10676816 DOI: 10.1016/S0092-8674(00)80670-4 |
0.597 |
|
| 2000 |
Hong-Geller E, Cerione RA. Cdc42 and Rac stimulate exocytosis of secretory granules by activating the IP(3)/calcium pathway in RBL-2H3 mast cells. The Journal of Cell Biology. 148: 481-94. PMID 10662774 DOI: 10.1083/Jcb.148.3.481 |
0.341 |
|
| 1999 |
Nomanbhoy T, Cerione RA. Fluorescence assays of Cdc42 interactions with target/effector proteins. Biochemistry. 38: 15878-84. PMID 10625453 DOI: 10.1021/Bi9916832 |
0.344 |
|
| 1999 |
Bagrodia S, Cerione RA. Pak to the future. Trends in Cell Biology. 9: 350-5. PMID 10461188 DOI: 10.1016/S0962-8924(99)01618-9 |
0.364 |
|
| 1999 |
Lin R, Cerione RA, Manor D. Specific contributions of the small GTPases Rho, Rac, and Cdc42 to Dbl transformation. The Journal of Biological Chemistry. 274: 23633-41. PMID 10438546 DOI: 10.1074/Jbc.274.33.23633 |
0.42 |
|
| 1999 |
Bagrodia S, Bailey D, Lenard Z, Hart M, Guan JL, Premont RT, Taylor SJ, Cerione RA. A tyrosine-phosphorylated protein that binds to an important regulatory region on the cool family of p21-activated kinase-binding proteins. The Journal of Biological Chemistry. 274: 22393-400. PMID 10428811 DOI: 10.1074/Jbc.274.32.22393 |
0.584 |
|
| 1999 |
Chen LM, Bagrodia S, Cerione RA, Galán JE. Requirement of p21-activated kinase (PAK) for Salmonella typhimurium-induced nuclear responses. The Journal of Experimental Medicine. 189: 1479-88. PMID 10224288 DOI: 10.1084/Jem.189.9.1479 |
0.4 |
|
| 1999 |
Yang W, Lin Q, Guan JL, Cerione RA. Activation of the Cdc42-associated tyrosine kinase-2 (ACK-2) by cell adhesion via integrin beta1. The Journal of Biological Chemistry. 274: 8524-30. PMID 10085085 DOI: 10.1074/Jbc.274.13.8524 |
0.397 |
|
| 1999 |
Wilson KF, Fortes P, Singh US, Ohno M, Mattaj IW, Cerione RA. The nuclear cap-binding complex is a novel target of growth factor receptor-coupled signal transduction. The Journal of Biological Chemistry. 274: 4166-73. PMID 9933612 DOI: 10.1074/Jbc.274.7.4166 |
0.408 |
|
| 1999 |
Berger AL, Cerione RA, Erickson JW. Delineation of two functionally distinct gammaPDE binding sites on the bovine retinal cGMP phosphodiesterase by a mutant gammaPDE subunit. Biochemistry. 38: 1293-9. PMID 9930990 DOI: 10.1021/Bi981683M |
0.338 |
|
| 1998 |
Nassar N, Hoffman GR, Manor D, Clardy JC, Cerione RA. Structures of Cdc42 bound to the active and catalytically compromised forms of Cdc42GAP. Nature Structural Biology. 5: 1047-52. PMID 9846874 DOI: 10.1038/4156 |
0.63 |
|
| 1998 |
McCallum SJ, Erickson JW, Cerione RA. Characterization of the association of the actin-binding protein, IQGAP, and activated Cdc42 with Golgi membranes. The Journal of Biological Chemistry. 273: 22537-44. PMID 9712880 DOI: 10.1074/Jbc.273.35.22537 |
0.334 |
|
| 1998 |
Osman MA, Cerione RA. Iqg1p, a yeast homologue of the mammalian IQGAPs, mediates cdc42p effects on the actin cytoskeleton. The Journal of Cell Biology. 142: 443-55. PMID 9679143 DOI: 10.1083/Jcb.142.2.443 |
0.393 |
|
| 1998 |
Nomanbhoy T, Cerione RA. Use of fluorescence spectroscopy to study the regulation of small G proteins. Methods in Molecular Biology (Clifton, N.J.). 84: 237-47. PMID 9666453 DOI: 10.1385/0-89603-488-7:237 |
0.345 |
|
| 1998 |
Wu WJ, Lin R, Cerione RA, Manor D. Transformation activity of Cdc42 requires a region unique to Rho- related proteins Journal of Biological Chemistry. 273: 16655-16658. PMID 9642217 DOI: 10.1074/Jbc.273.27.16655 |
0.443 |
|
| 1998 |
Leonard DA, Lin R, Cerione RA, Manor D. Biochemical studies of the mechanism of action of the Cdc42-GTPase- activating protein Journal of Biological Chemistry. 273: 16210-16215. PMID 9632678 DOI: 10.1074/Jbc.273.26.16210 |
0.411 |
|
| 1998 |
Hoffman GR, Nassar N, Oswald RE, Cerione RA. Fluoride activation of the Rho family GTP-binding protein Cdc42Hs. The Journal of Biological Chemistry. 273: 4392-9. PMID 9468490 DOI: 10.1074/Jbc.273.8.4392 |
0.634 |
|
| 1998 |
Singh US, Li Q, Cerione R. Identification of the eukaryotic initiation factor 5A as a retinoic acid-stimulated cellular binding partner for tissue transglutaminase II. The Journal of Biological Chemistry. 273: 1946-50. PMID 9442029 DOI: 10.1074/Jbc.273.4.1946 |
0.337 |
|
| 1998 |
Lin R, Bagrodia S, Cerione R, Manor D. A novel Cdc42Hs mutant induces cellular transformation. Current Biology : Cb. 7: 794-7. PMID 9368762 DOI: 10.1016/S0960-9822(06)00338-1 |
0.432 |
|
| 1998 |
Cerione R. A difference of opinion or a matter of perspective? Trends in Biochemical Sciences. 23: 100. DOI: 10.1016/S0968-0004(98)01178-5 |
0.344 |
|
| 1997 |
Yang W, Cerione RA. Cloning and characterization of a novel Cdc42-associated tyrosine kinase, ACK-2, from bovine brain Journal of Biological Chemistry. 272: 24819-24824. PMID 9312079 DOI: 10.1074/Jbc.272.40.24819 |
0.393 |
|
| 1997 |
Erickson JW, Cerione RA, Hart MJ. Identification of an actin cytoskeletal complex that includes IQGAP and the CDc42 GTPase Journal of Biological Chemistry. 272: 24443-24447. PMID 9305904 DOI: 10.1074/Jbc.272.39.24443 |
0.399 |
|
| 1997 |
Li Q, Cerione RA. Communication between Switch II and Switch III of the transducin α subunit is essential for target activation Journal of Biological Chemistry. 272: 21673-21676. PMID 9268292 DOI: 10.1074/Jbc.272.35.21673 |
0.35 |
|
| 1997 |
Gosser YQ, Nomanbhoy TK, Aghazadeh B, Manor D, Combs C, Cerione RA, Rosen MK. C-terminal binding domain of Rho GDP-dissociation inhibitor directs N-terminal inhibitory peptide to GTPases. Nature. 387: 814-9. PMID 9194563 DOI: 10.1038/42961 |
0.36 |
|
| 1997 |
Gamett DC, Pearson G, Cerione RA, Friedberg I. Secondary dimerization between members of the epidermal growth factor receptor family Journal of Biological Chemistry. 272: 12052-12056. PMID 9115272 DOI: 10.1074/Jbc.272.18.12052 |
0.341 |
|
| 1997 |
Adra CN, Manor D, Ko JL, Zhu S, Horiuchi T, Van Aelst L, Cerione RA, Lim B. RhoGDIgamma: a GDP-dissociation inhibitor for Rho proteins with preferential expression in brain and pancreas. Proceedings of the National Academy of Sciences of the United States of America. 94: 4279-84. PMID 9113980 DOI: 10.1073/Pnas.94.9.4279 |
0.38 |
|
| 1997 |
Leonard DA, Satoskar RS, Wu WJ, Bagrodia S, Cerione RA, Manor D. Use of a fluorescence spectroscopic readout to characterize the interactions of Cdc42Hs with its target/effector, mPAK-3 Biochemistry. 36: 1173-1180. PMID 9033409 DOI: 10.1021/Bi9622837 |
0.369 |
|
| 1997 |
Berger AL, Cerione RA, Erickson JW. Real time conformational changes in the retinal phosphodiesterase γ subunit monitored by resonance energy transfer Journal of Biological Chemistry. 272: 2714-2721. PMID 9006909 DOI: 10.1074/Jbc.272.5.2714 |
0.329 |
|
| 1996 |
Glaven JA, Whitehead IP, Nomanbhoy T, Kay R, Cerione RA. Lfc and Lsc oncoproteins represent two new guanine nucleotide exchange factors for the Rho GTP-binding protein Journal of Biological Chemistry. 271: 27374-27381. PMID 8910315 DOI: 10.1074/Jbc.271.44.27374 |
0.414 |
|
| 1996 |
Singh US, Cerione RA. Biochemical effects of retinoic acid on GTP-binding protein/transglutaminases in HeLa cells: Stimulation of GTP-binding and transglutaminase activity, membrane association, and phosphatidylinositol lipid turnover Journal of Biological Chemistry. 271: 27292-27298. PMID 8910304 DOI: 10.1074/Jbc.271.44.27292 |
0.347 |
|
| 1996 |
Erickson JW, Zhang CJ, Kahn RA, Evans T, Cerione RA. Mammalian Cdc42 is a brefeldin A-sensitive component of the Golgi apparatus Journal of Biological Chemistry. 271: 26850-26854. PMID 8900167 DOI: 10.1074/Jbc.271.43.26850 |
0.375 |
|
| 1996 |
Zheng Y, Glaven JA, Wu WJ, Cerione RA. Phosphatidylinositol 4,5-bisphosphate provides an alternative to guanine nucleotide exchange factors by stimulating the dissociation of GDP from Cdc42Hs. The Journal of Biological Chemistry. 271: 23815-9. PMID 8798610 DOI: 10.1074/Jbc.271.39.23815 |
0.401 |
|
| 1996 |
Cerione RA, Zheng Y. The Dbl family of oncogenes Current Opinion in Cell Biology. 8: 216-222. PMID 8791419 DOI: 10.1016/S0955-0674(96)80068-8 |
0.373 |
|
| 1996 |
McCallum SJ, Wu WJ, Cerione RA. Identification of a putative effector for Cdc42Hs with high sequence similarity to the RasGAP-related protein IQGAP1 and a Cdc42Hs binding partner with similarity to IQGAP2 Journal of Biological Chemistry. 271: 21732-21737. PMID 8702968 DOI: 10.1074/Jbc.271.36.21732 |
0.345 |
|
| 1996 |
Zheng Y, Zangrilli D, Cerione RA, Eva A. The pleckstrin homology domain mediates transformation by oncogenic Dbl through specific intracellular targeting Journal of Biological Chemistry. 271: 19017-19020. PMID 8702569 DOI: 10.1074/Jbc.271.32.19017 |
0.348 |
|
| 1996 |
Nomanbhoy TK, Cerione RA. Characterization of the interaction between RhoGDI and Cdc42Hs using fluorescence spectroscopy Journal of Biological Chemistry. 271: 10004-10009. PMID 8626553 DOI: 10.1074/Jbc.271.17.10004 |
0.348 |
|
| 1996 |
Nomanbhoy TK, Leonard DA, Manor D, Cerione RA. Investigation of the GTP-binding/GTPase cycle of Cdc42Hs using extrinsic reporter group fluorescence Biochemistry. 35: 4602-4608. PMID 8605211 DOI: 10.1021/Bi951743D |
0.34 |
|
| 1995 |
Zheng Y, Bender A, Cerione RA. Interactions among proteins involved in bud-site selection and bud-site assembly in Saccharomyces cerevisiae Journal of Biological Chemistry. 270: 626-630. PMID 7822288 DOI: 10.1074/Jbc.270.2.626 |
0.4 |
|
| 1995 |
Zheng Y, Olson MF, Hall A, Cerione RA, Toksoz D. Direct involvement of the small GTP-binding protein Rho in lbc oncogene function Journal of Biological Chemistry. 270: 9031-9034. PMID 7721814 DOI: 10.1074/Jbc.270.16.9031 |
0.404 |
|
| 1995 |
Platko JV, Leonard DA, Adra CN, Shaw RJ, Cerione RA, Lim B. A single residue can modify target-binding affinity and activity of the functional domain of the Rho-subfamily GDP dissociation inhibitors Proceedings of the National Academy of Sciences of the United States of America. 92: 2974-2978. PMID 7708758 DOI: 10.1073/Pnas.92.7.2974 |
0.365 |
|
| 1995 |
Gamett DC, Greene T, Wagreich AR, Kim HH, Koland JG, Cerione RA. Heregulin-stimulated signaling in rat pheochromocytoma cells. Evidence for ErbB3 interactions with Neu/ErbB2 and p85 Journal of Biological Chemistry. 270: 19022-19027. PMID 7642563 DOI: 10.1074/Jbc.270.32.19022 |
0.368 |
|
| 1995 |
Bagrodia S, Taylor SJ, Creasy CL, Chernoff J, Cerione RA. Identification of a mouse p21Cdc42/Rac activated kinase Journal of Biological Chemistry. 270: 22731-22737. PMID 7559398 DOI: 10.1074/Jbc.270.39.22731 |
0.405 |
|
| 1995 |
Bagrodia S, Derijard B, Davis RJ, Cerione RA. Cdc42 and PAK-mediated signaling leads to Jun kinase and p38 mitogen- activated protein kinase activation Journal of Biological Chemistry. 270: 27995-27998. PMID 7499279 DOI: 10.1074/Jbc.270.47.27995 |
0.359 |
|
| 1995 |
Zheng Y, Hart MJ, Cerione RA. Guanine nucleotide exchange catalyzed by dbl oncogene product. Methods in Enzymology. 256: 77-84. PMID 7476457 DOI: 10.1016/0076-6879(95)56011-4 |
0.379 |
|
| 1995 |
Cerione RA, Leonard D, Zheng Y. Purification of baculovirus-expressed Cdc42Hs Methods in Enzymology. 256: 11-15. PMID 7476423 DOI: 10.1016/0076-6879(95)56004-1 |
0.359 |
|
| 1995 |
Singh US, Erickson JW, Cerione RA. Identification and biochemical characterization of an 80 kilodalton GTP-binding/transglutaminase from rabbit liver nuclei Biochemistry. 34: 15863-15871. DOI: 10.1021/Bi00048A032 |
0.346 |
|
| 1994 |
Guy PM, Platko JV, Cantley LC, Cerione RA, Carraway KL. Insect cell-expressed p180erbB3 possesses an impaired tyrosine kinase activity Proceedings of the National Academy of Sciences of the United States of America. 91: 8132-8136. PMID 8058768 DOI: 10.1073/Pnas.91.17.8132 |
0.52 |
|
| 1994 |
Cerione RA. [31] Fluorescence assays for G-protein interactions Methods in Enzymology. 237: 409-423. PMID 7935014 DOI: 10.1016/S0076-6879(94)37078-8 |
0.334 |
|
| 1994 |
Gamett DC, Cerione RA. Oncogenically activated or ligand-stimulated neu kinase stimulates neurite outgrowth in PC12 cells Febs Letters. 351: 335-339. PMID 7915994 DOI: 10.1016/0014-5793(94)00855-8 |
0.344 |
|
| 1993 |
Barfod ET, Zheng Y, Kuang WJ, Hart MJ, Evans T, Cerione RA, Ashkenazi A. Cloning and expression of a human CDC42 GTPase-activating protein reveals a functional SH3-binding domain. The Journal of Biological Chemistry. 268: 26059-62. PMID 8253717 |
0.306 |
|
| 1993 |
Carraway KL, Cerione RA. Fluorescent-labeled growth factor molecules serve as probes for receptor binding and endocytosis Biochemistry. 32: 12039-12045. PMID 8218281 DOI: 10.1021/Bi00096A014 |
0.32 |
|
| 1993 |
Adra CN, Ko J, Leonard D, Wirth LJ, Cerione RA, Lim B. Identification of a novel protein with GDP dissociation inhibitor activity for the ras-like proteins CDC42Hs and rac I Genes Chromosomes and Cancer. 8: 253-261. PMID 7512369 DOI: 10.1002/Gcc.2870080408 |
0.31 |
|
| 1992 |
Hart MJ, Maru Y, Leonard D, Witte ON, Evans T, Cerione RA. A GDP dissociation inhibitor that serves as a GTPase inhibitor for the ras-like protein CDC42HS Science. 258: 812-815. PMID 1439791 DOI: 10.1126/Science.1439791 |
0.364 |
|
| 1992 |
Narasimhan V, Hamill O, Cerione RA. The effects of the normal and oncogenic forms of the neu tyrosine kinase, and the corresponding forms of an immunoglobulin E receptor/neu tyrosine kinase fusion protein, on Xenopus oocyte maturation Febs Letters. 303: 164-168. PMID 1351469 DOI: 10.1016/0014-5793(92)80510-N |
0.361 |
|
| 1991 |
Hart MJ, Eva A, Evans T, Aaronson SA, Cerione RA. Catalysis of guanine nucleotide exchange on the CDC42Hs protein by the dbl oncogene product Nature. 354: 311-314. PMID 1956381 DOI: 10.1038/354311A0 |
0.399 |
|
| 1991 |
Evans T, Hart MJ, Cerione RA. The Ras superfamilies: regulatory proteins and post-translational modifications. Current Opinion in Cell Biology. 3: 185-91. PMID 1909148 DOI: 10.1016/0955-0674(91)90137-N |
0.373 |
|
| 1991 |
Cerione RA. Reconstitution of receptor/GTP-binding protein interactions Bba - Reviews On Biomembranes. 1071: 473-501. PMID 1661159 DOI: 10.1016/0304-4157(91)90007-J |
0.314 |
|
| 1990 |
Koland JG, Cerione RA. Activation of the EGF receptor tyrosine kinase by divalent metal ions: comparison of holoreceptor and isolated kinase domain properties. Biochimica Et Biophysica Acta. 1052: 489-98. PMID 2354210 DOI: 10.1016/0167-4889(90)90160-F |
0.365 |
|
| 1990 |
Carraway KL, Koland JG, Cerione RA. Location of the epidermal growth factor binding site on the EGF receptor. A resonance energy transfer study Biochemistry. 29: 8741-8747. PMID 2271554 DOI: 10.1021/Bi00489A034 |
0.343 |
|
| 1990 |
Guy PM, Koland JG, Cerione RA. Rhodopsin-stimulated activation-deactivation cycle of transducin: kinetics of the intrinsic fluorescence response of the alpha subunit. Biochemistry. 29: 6954-64. PMID 2223753 DOI: 10.1021/Bi00482A003 |
0.305 |
|
| 1990 |
Koland JG, O'Brien KM, Cerione RA. Expression of epidermal growth factor receptor sequences as E. coli fusion proteins: applications in the study of tyrosine kinase function. Biochemical and Biophysical Research Communications. 166: 90-100. PMID 2154210 DOI: 10.1016/0006-291X(90)91915-F |
0.32 |
|
| 1987 |
Cerione RA, Gierschik P, Staniszewski C, Benovic JL, Codina J, Somers R, Birnbaumer L, Spiegel AM, Lefkowitz RJ, Caron MG. Functional differences in the beta gamma complexes of transducin and the inhibitory guanine nucleotide regulatory protein. Biochemistry. 26: 1485-91. PMID 3032251 DOI: 10.1021/Bi00379A041 |
0.614 |
|
| 1987 |
Benovic JL, Staniszewski C, Cerione RA, Codina J, Lefkowitz RJ, Caron MG. The mammalian βadrenergic receptor: Structural and functional characterization of the carbohydrate moiety Journal of Receptors and Signal Transduction. 7: 257-281. PMID 2887651 DOI: 10.3109/10799898709054989 |
0.629 |
|
| 1985 |
Cerione RA, Codina J, Kilpatrick BF, Staniszewski C, Gierschik P, Somers RL, Spiegel AM, Birnbaumer L, Caron MG, Lefkowitz RJ. Transducin and the inhibitory nucleotide regulatory protein inhibit the stimulatory nucleotide regulatory protein mediated stimulation of adenylate cyclase in phospholipid vesicle systems. Biochemistry. 24: 4499-503. PMID 3933556 DOI: 10.1021/Bi00338A002 |
0.557 |
|
| 1985 |
Cerione RA, Staniszewski C, Caron MG, Lefkowitz RJ, Codina J, Birnbaumer L. A role for Ni in the hormonal stimulation of adenylate cyclase. Nature. 318: 293-5. PMID 2999605 DOI: 10.1038/318293a0 |
0.551 |
|
| 1985 |
Birnbaumer L, Codina J, Mattera R, Cerione RA, Hildebrandt JD, Sunyer T, Rojas FJ, Caron MG, Lefkowitz RJ, Iyengar R. Regulation of hormone receptors and adenylyl cyclases by guanine nucleotide binding N proteins. Recent Progress in Hormone Research. 41: 41-99. PMID 2996090 DOI: 10.1016/B978-0-12-571141-8.50006-8 |
0.565 |
|
| 1985 |
Lefkowitz RJ, Cerione RA, Codina J, Birnbaumer L, Caron MG. Reconstitution of the beta-adrenergic receptor. The Journal of Membrane Biology. 87: 1-12. PMID 2865370 DOI: 10.1007/BF01870694 |
0.474 |
|
| 1984 |
Cerione RA, Codina J, Benovic JL, Lefkowitz RJ, Birnbaumer L, Caron MG. The mammalian β2-adrenergic receptor: Reconstitution of functional interactions between pure receptor and pure stimulatory nucleotide binding protein of the adenylate cyclase system Biochemistry. 23: 4519-4525. PMID 6149763 DOI: 10.1021/Bi00315A003 |
0.671 |
|
| 1984 |
Strulovici B, Cerione RA, Kilpatrick BF, Caron MG, Lefkowitz RJ. Direct demonstration of impaired functionality of a purified desensitized beta-adrenergic receptor in a reconstituted system. Science (New York, N.Y.). 225: 837-40. PMID 6089331 DOI: 10.1126/Science.6089331 |
0.564 |
|
| 1983 |
Cerione RA, Strulovici B, Benovic JL, Lefkowitz RJ, Caron MG. Pure β-adrenergic receptor: the single polypeptide confers catecholamine responsiveness to adenylate cyclase Nature. 306: 562-566. PMID 6316161 DOI: 10.1038/306562A0 |
0.637 |
|
| 1983 |
Cerione RA, Strulovici B, Benovic JL, Strader CD, Caron MG, Lefkowitz RJ. Reconstitution of beta-adrenergic receptors in lipid vesicles: affinity chromatography-purified receptors confer catecholamine responsiveness on a heterologous adenylate cyclase system. Proceedings of the National Academy of Sciences of the United States of America. 80: 4899-903. PMID 6308659 DOI: 10.1073/Pnas.80.16.4899 |
0.648 |
|
| 1983 |
Cerione RA, McCarty RE, Hammes GG. Spatial relationships between specific sites on reconstituted chloroplast proton adenosinetriphosphatase and the phospholipid vesicle surface. Biochemistry. 22: 769-76. PMID 6220736 DOI: 10.1021/Bi00273A010 |
0.474 |
|
| 1982 |
Cerione RA, Hammes GG. Structural mapping of nucleotide binding sites on chloroplast coupling factor. Biochemistry. 21: 745-52. PMID 6462173 DOI: 10.1021/Bi00533A026 |
0.51 |
|
| 1981 |
Cerione RA, Hammes GG. Nucleotide interactions with the dicyclohexylcarbodiimide-sensitive adenosinetriphosphatase from spinach chloroplasts. Biochemistry. 20: 3359-65. PMID 6455155 DOI: 10.1021/Bi00515A008 |
0.52 |
|
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