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Richard A. Cerione - Publications

Chemistry and Chemical Biology Cornell University, Ithaca, NY, United States 
Signal Transduction Mechanisms

283 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Chang WH, Thi Nguyen TT, Hsu CH, Bryant KL, Kim HJ, Ying H, Erickson JW, Der CJ, Cerione RA, Antonyak MA. KRAS-dependent cancer cells promote survival by producing exosomes enriched in Survivin. Cancer Letters. PMID 34111513 DOI: 10.1016/j.canlet.2021.05.031  0.68
2021 Gao Y, Eskici G, Ramachandran S, Poitevin F, Seven AB, Panova O, Skiniotis G, Cerione RA. Structure of the visual signaling complex between transducin and phosphodiesterase 6. Molecular Cell. 81: 2496. PMID 34087182 DOI: 10.1016/j.molcel.2021.05.006  0.72
2021 Wang F, Cerione RA, Antonyak MA. Isolation and characterization of extracellular vesicles produced by cell lines. Star Protocols. 2: 100295. PMID 33532740 DOI: 10.1016/j.xpro.2021.100295  0.68
2021 Abril YLN, Fernandez IR, Hong JY, Chiang YL, Kutateladze DA, Zhao Q, Yang M, Hu J, Sadhukhan S, Li B, He B, Remick B, Bai JJ, Mullmann J, Wang F, ... ... Cerione RA, et al. Pharmacological and genetic perturbation establish SIRT5 as a promising target in breast cancer. Oncogene. PMID 33479498 DOI: 10.1038/s41388-020-01637-w  0.68
2021 Wang J, Zhuang X, Greene KS, Si H, Antonyak MA, Druso JE, Wilson KF, Cerione RA, Feng Q, Wang H. Cdc42 functions as a regulatory node for tumour-derived microvesicle biogenesis. Journal of Extracellular Vesicles. 10: e12051. PMID 33473262 DOI: 10.1002/jev2.12051  1
2021 Chang WH, Cerione RA, Antonyak MA. Extracellular Vesicles and Their Roles in Cancer Progression. Methods in Molecular Biology (Clifton, N.J.). 2174: 143-170. PMID 32813249 DOI: 10.1007/978-1-0716-0759-6_10  0.68
2020 Hur YH, Feng S, Wilson KF, Cerione RA, Antonyak MA. Embryonic Stem-Cell-Derived Extracellular Vesicles Maintain ESC Stemness by Activating FAK. Developmental Cell. PMID 33321103 DOI: 10.1016/j.devcel.2020.11.017  0.72
2020 Gao Y, Eskici G, Ramachandran S, Poitevin F, Seven AB, Panova O, Skiniotis G, Cerione RA. Structure of the Visual Signaling Complex between Transducin and Phosphodiesterase 6. Molecular Cell. PMID 33007200 DOI: 10.1016/j.molcel.2020.09.013  0.72
2020 Lukey MJ, Greene KS, Cerione RA. Lysine succinylation and SIRT5 couple nutritional status to glutamine catabolism. Molecular & Cellular Oncology. 7: 1735284. PMID 32391426 DOI: 10.1080/23723556.2020.1735284  1
2020 Panizza E, Cerione RA, Antonyak MA. Exosomes as Sentinels against Bacterial Pathogens. Developmental Cell. 53: 138-139. PMID 32315610 DOI: 10.1016/J.Devcel.2020.03.022  0.68
2020 Endo M, Druso JE, Cerione RA. The two splice variant forms of Cdc42 exert distinct and essential functions in neurogenesis. The Journal of Biological Chemistry. PMID 32071086 DOI: 10.1074/Jbc.Ra119.011837  0.48
2020 Pumar OYT, Wilson KF, Cerione RA. Abstract 1447: Elucidating the mechanism of Dock7-mediated cellular transformation Immunology. DOI: 10.1158/1538-7445.Am2020-1447  0.72
2019 Li Y, Ramachandran S, Nguyen TT, Stalnecker CA, Cerione RA, Erickson JW. The activation loop and substrate-binding cleft of glutaminase C are allosterically coupled. The Journal of Biological Chemistry. PMID 31871054 DOI: 10.1074/Jbc.Ra119.010314  0.72
2019 Greene KS, Lukey MJ, Wang X, Blank B, Druso JE, Lin MJ, Stalnecker CA, Zhang C, Negrón Abril Y, Erickson JW, Wilson KF, Lin H, Weiss RS, Cerione RA. SIRT5 stabilizes mitochondrial glutaminase and supports breast cancer tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America. PMID 31843902 DOI: 10.1073/Pnas.1911954116  1
2019 Hur YH, Cerione RA, Antonyak MA. Extracellular Vesicles and Their Roles in Stem Cell Biology: Concise Review. Stem Cells (Dayton, Ohio). PMID 31828924 DOI: 10.1002/Stem.3140  0.68
2019 Bordeleau F, Wang W, Simmons A, Antonyak MA, Cerione RA, Reinhart-King CA. Tissue transglutaminase regulates tumor cell tensional homeostasis by increasing contractility. Journal of Cell Science. PMID 31822629 DOI: 10.1242/Jcs.231134  0.68
2019 Lukey MJ, Cluntun AA, Katt WP, Lin MJ, Druso JE, Ramachandran S, Erickson JW, Le HH, Wang ZE, Blank B, Greene KS, Cerione RA. Liver-Type Glutaminase GLS2 Is a Druggable Metabolic Node in Luminal-Subtype Breast Cancer. Cell Reports. 29: 76-88.e7. PMID 31577957 DOI: 10.1016/J.Celrep.2019.08.076  1
2019 Katt WP, Lukey MJ, Cerione RA. Starving the Devourer: Cutting Cancer Off from Its Favorite Foods. Cell Chemical Biology. 26: 1197-1199. PMID 31539503 DOI: 10.1016/J.Chembiol.2019.09.005  1
2019 McDermott L, Koes D, Mohammed S, Iyer P, Boby M, Balasubramanian V, Geedy M, Katt W, Cerione R. GAC inhibitors with a 4-hydroxypiperidine spacer: Requirements for potency. Bioorganic & Medicinal Chemistry Letters. 126632. PMID 31474484 DOI: 10.1016/J.Bmcl.2019.126632  0.4
2019 Katt WP, Cerione RA. Inhibition of cancer metabolism: a patent landscape. Pharmaceutical Patent Analyst. PMID 31414969 DOI: 10.4155/Ppa-2019-0012  0.64
2019 Gao Y, Hu H, Ramachandran S, Erickson JW, Cerione RA, Skiniotis G. Structures of the Rhodopsin-Transducin Complex: Insights into G-Protein Activation. Molecular Cell. PMID 31300275 DOI: 10.2210/Pdb6Oy9/Pdb  0.72
2019 Latifkar A, Hur YH, Sanchez JC, Cerione RA, Antonyak MA. New insights into extracellular vesicle biogenesis and function. Journal of Cell Science. 132. PMID 31263077 DOI: 10.1242/Jcs.222406  0.68
2019 Gao Y, Erickson JW, Cerione RA, Ramachandran S. Reconstitution of the Rhodopsin-Transducin Complex into Lipid Nanodiscs. Methods in Molecular Biology (Clifton, N.J.). 2009: 317-324. PMID 31152414 DOI: 10.1007/978-1-4939-9532-5_24  0.72
2019 Gao Y, Erickson JW, Cerione RA, Ramachandran S. Purification of the Rhodopsin-Transducin Complex for Structural Studies. Methods in Molecular Biology (Clifton, N.J.). 2009: 307-315. PMID 31152413 DOI: 10.1007/978-1-4939-9532-5_23  0.72
2019 Schwager SC, Bordeleau F, Zhang J, Antonyak MA, Cerione RA, Reinhart-King C. Matrix stiffness regulates microvesicle-induced fibroblast activation. American Journal of Physiology. Cell Physiology. PMID 31017799 DOI: 10.1152/Ajpcell.00418.2018  0.68
2019 Latifkar A, Ling L, Hingorani A, Johansen E, Clement A, Zhang X, Hartman J, Fischbach C, Lin H, Cerione RA, Antonyak MA. Loss of Sirtuin 1 Alters the Secretome of Breast Cancer Cells by Impairing Lysosomal Integrity. Developmental Cell. PMID 30982660 DOI: 10.1016/J.Devcel.2019.03.011  0.68
2019 Antonyak MA, Lukey MJ, Cerione RA. Lipid-filled vesicles modulate macrophages. Science (New York, N.Y.). 363: 931-932. PMID 30819952 DOI: 10.1126/Science.Aaw6765  1
2018 Katt WP, Antonyak MA, Cerione RA. Opening up about Tissue Transglutaminase: When Conformation Matters More than Enzymatic Activity. Med One. 3. PMID 30662957 DOI: 10.20900/mo.20180011  0.68
2018 Kohle FFE, Hinckley JA, Li S, Dhawan N, Katt WP, Erstling JA, Werner-Zwanziger U, Zwanziger J, Cerione RA, Wiesner UB. Amorphous Quantum Nanomaterials. Advanced Materials (Deerfield Beach, Fla.). e1806993. PMID 30516861 DOI: 10.1002/Adma.201806993  0.64
2018 Katt WP, Blobel NJ, Komarova S, Antonyak MA, Nakano I, Cerione RA. A small molecule regulator of tissue transglutaminase conformation inhibits the malignant phenotype of cancer cells. Oncotarget. 9: 34379-34397. PMID 30344949 DOI: 10.18632/Oncotarget.26193  0.68
2018 Latifkar A, Cerione RA, Antonyak MA. Probing the mechanisms of extracellular vesicle biogenesis and function in cancer. Biochemical Society Transactions. PMID 30301841 DOI: 10.1042/Bst20180523  0.68
2018 Milano SK, Wang C, Erickson J, Cerione RA, Ramachandran S. Gain-of-function screen of alpha transducin identifies an essential phenylalanine residue necessary for full effector activation. The Journal of Biological Chemistry. PMID 30266806 DOI: 10.1074/Jbc.Ra118.003746  0.72
2018 Lukey MJ, Katt WP, Cerione RA. Targeting Therapy Resistance: When Glutamine Catabolism Becomes Essential. Cancer Cell. 33: 795-797. PMID 29763620 DOI: 10.1016/J.Ccell.2018.04.009  1
2018 Katt WP, Antonyak MA, Cerione RA. The diamond anniversary of tissue transglutaminase: a protein of many talents. Drug Discovery Today. PMID 29362136 DOI: 10.1016/J.Drudis.2018.01.037  0.68
2018 Huang Q, Stalnecker C, Zhang C, McDermott LA, Iyer P, O'Neill J, Reimer S, Cerione RA, Katt WP. Characterization of the interactions of potent allosteric inhibitors with glutaminase C, a key enzyme in cancer cell glutamine metabolism. The Journal of Biological Chemistry. PMID 29317493 DOI: 10.1074/Jbc.M117.810101  0.64
2018 Latifkar A, Ling L, Zhang X, Fischbach C, Lin H, Cerione R, Antonyak M. Abstract 4506: Loss of SIRT1 alters the secretome of breast cancer cells by impairing lysosomal integrity Cancer Research. 78: 4506-4506. DOI: 10.1158/1538-7445.Am2018-4506  0.68
2018 Katt WP, Cerione RA. Abstract A156: Traditional chemotherapeutic agents as selective inhibitors of glutaminase isozymes Molecular Cancer Therapeutics. 17. DOI: 10.1158/1535-7163.Targ-17-A156  0.64
2017 Yoo SM, Cerione RA, Antonyak MA. The Arf-GAP and Protein Scaffold Cat1/Git1 as a Multifaceted Regulator of Cancer Progression. Small Gtpases. 0. PMID 28981399 DOI: 10.1080/21541248.2017.1362496  0.68
2017 Gao Y, Westfield G, Erickson JW, Cerione RA, Skiniotis G, Ramachandran S. Isolation and Structure-function Characterization of a Signaling-active Rhodopsin-G protein Complex. The Journal of Biological Chemistry. PMID 28655769 DOI: 10.1074/Jbc.M117.797100  0.72
2017 de Opakua AI, Parag-Sharma K, DiGiacomo V, Merino N, Leyme A, Marivin A, Villate M, Nguyen LT, de la Cruz-Morcillo MA, Blanco-Canosa JB, Ramachandran S, Baillie GS, Cerione RA, Blanco FJ, Garcia-Marcos M. Molecular mechanism of Gαi activation by non-GPCR proteins with a Gα-Binding and Activating motif. Nature Communications. 8: 15163. PMID 28516903 DOI: 10.1038/Ncomms15163  0.72
2017 Sullivan KE, Cerione RA, Wilson KF. ALDH1A3 in CSCs. Aging. PMID 28476022 DOI: 10.18632/aging.101236  0.72
2017 Sullivan KE, Rojas K, Cerione RA, Nakano I, Wilson KF. The stem cell/cancer stem cell marker ALDH1A3 regulates the expression of the survival factor tissue transglutaminase, in mesenchymal glioma stem cells. Oncotarget. 8: 22325-22343. PMID 28423611 DOI: 10.18632/Oncotarget.16479  0.72
2017 Cluntun AA, Lukey MJ, Cerione RA, Locasale JW. Glutamine Metabolism in Cancer: Understanding the Heterogeneity. Trends in Cancer. 3: 169-180. PMID 28393116 DOI: 10.1016/J.Trecan.2017.01.005  1
2017 Feng Q, Zhang C, Lum D, Druso JE, Blank B, Wilson KF, Welm A, Antonyak MA, Cerione RA. A class of extracellular vesicles from breast cancer cells activates VEGF receptors and tumour angiogenesis. Nature Communications. 8: 14450. PMID 28205552 DOI: 10.1038/Ncomms14450  1
2017 Stalnecker CA, Erickson JW, Cerione RA. Conformational Changes in the Activation Loop of Mitochondrial Glutaminase C: A Direct Fluorescence Read-Out that Distinguishes the Binding of Allosteric Inhibitors from Activators. The Journal of Biological Chemistry. PMID 28196863 DOI: 10.1074/Jbc.M116.758219  0.6
2017 Katt WP, Lukey MJ, Cerione RA. A tale of two glutaminases: homologous enzymes with distinct roles in tumorigenesis. Future Medicinal Chemistry. PMID 28111979 DOI: 10.4155/Fmc-2016-0190  1
2017 French KC, Antonyak MA, Cerione RA. Extracellular vesicle docking at the cellular port: Extracellular vesicle binding and uptake. Seminars in Cell & Developmental Biology. PMID 28104520 DOI: 10.1016/J.Semcdb.2017.01.002  0.68
2017 Yoo SM, Latifkar A, Cerione RA, Antonyak MA. Cool-associated tyrosine phosphorylated protein-1 is required for the anchorage-independent growth of cervical carcinoma cells by binding paxillin and promoting AKT activation. The Journal of Biological Chemistry. PMID 28100775 DOI: 10.1074/Jbc.M116.769190  0.68
2016 Stalnecker CA, Cluntun AA, Cerione RA. Balancing redox stress: anchorage-independent growth requires reductive carboxylation. Translational Cancer Research. 5: S433-S437. PMID 28232903 DOI: 10.21037/Tcr.2016.09.02  0.84
2016 Lukey MJ, Katt WP, Cerione RA. Targeting amino acid metabolism for cancer therapy. Drug Discovery Today. PMID 27988359 DOI: 10.1016/J.Drudis.2016.12.003  1
2016 Kreger BT, Johansen ER, Cerione RA, Antonyak MA. The Enrichment of Survivin in Exosomes from Breast Cancer Cells Treated with Paclitaxel Promotes Cell Survival and Chemoresistance. Cancers. 8. PMID 27941677 DOI: 10.3390/Cancers8120111  0.68
2016 Song YH, Warncke C, Choi SJ, Choi S, Chiou AE, Ling L, Liu HY, Daniel S, Antonyak MA, Cerione RA, Fischbach C. Breast cancer-derived extracellular vesicles stimulate myofibroblast differentiation and pro-angiogenic behavior of adipose stem cells. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 27913195 DOI: 10.1016/J.Matbio.2016.11.008  0.68
2016 Antonyak MA, Cerione RA. The distinct traits of extracellular vesicles generated by transformed cells. Small Gtpases. 0. PMID 27754746 DOI: 10.1080/21541248.2016.1249044  0.68
2016 Bussche L, Rauner G, Antonyak M, Syracuse B, McDowell M, Brown AM, Cerione RA, Van de Walle GR. Microvesicle-Mediated Wnt/b-catenin Signaling Promotes Interspecies Mammary Stem/Progenitor Cell Growth. The Journal of Biological Chemistry. PMID 27733685 DOI: 10.1074/Jbc.M116.726117  0.48
2016 Li Y, Erickson JW, Stalnecker CA, Katt WP, Huang Q, Cerione RA, Ramachandran S. Mechanistic Basis of Glutaminase Activation: A Key Enzyme that Promotes Glutamine Metabolism in Cancer Cells. The Journal of Biological Chemistry. PMID 27542409 DOI: 10.1074/Jbc.M116.720268  1
2016 Kreger BT, Dougherty AL, Greene KS, Cerione RA, Antonyak MA. Microvesicle Cargo and Function Changes Upon the Induction of Cellular Transformation. The Journal of Biological Chemistry. PMID 27440046 DOI: 10.1074/Jbc.M116.725705  1
2016 Zhang X, Khan S, Jiang H, Antonyak MA, Chen X, Spiegelman NA, Shrimp JH, Cerione RA, Lin H. Identifying the functional contribution of the defatty-acylase activity of SIRT6. Nature Chemical Biology. PMID 27322069 DOI: 10.1038/Nchembio.2106  0.68
2016 Desrochers LM, Bordeleau F, Reinhart-King CA, Cerione RA, Antonyak MA. Microvesicles provide a mechanism for intercellular communication by embryonic stem cells during embryo implantation. Nature Communications. 7: 11958. PMID 27302045 DOI: 10.1038/Ncomms11958  0.4
2016 Desrochers LM, Antonyak MA, Cerione RA. Extracellular Vesicles: Satellites of Information Transfer in Cancer and Stem Cell Biology. Developmental Cell. 37: 301-9. PMID 27219060 DOI: 10.1016/J.Devcel.2016.04.019  0.68
2016 Lukey MJ, Greene KS, Erickson JW, Wilson KF, Cerione RA. The oncogenic transcription factor c-Jun regulates glutaminase expression and sensitizes cells to glutaminase-targeted therapy. Nature Communications. 7: 11321. PMID 27089238 DOI: 10.1038/Ncomms11321  1
2016 Hall J, Prabhakar S, Balaj L, Lai CP, Cerione RA, Breakefield XO. Delivery of Therapeutic Proteins via Extracellular Vesicles: Review and Potential Treatments for Parkinson's Disease, Glioma, and Schwannoma. Cellular and Molecular Neurobiology. PMID 27017608 DOI: 10.1007/S10571-015-0309-0  0.4
2016 McDermott LA, Iyer P, Vernetti L, Rimer S, Sun J, Boby M, Yang T, Fioravanti M, O'Neill J, Wang L, Drakes D, Katt W, Huang Q, Cerione R. Design and evaluation of novel glutaminase inhibitors. Bioorganic & Medicinal Chemistry. PMID 26988803 DOI: 10.1016/J.Bmc.2016.03.009  0.4
2016 Druso JE, Endo M, Lin MJ, Peng X, Antonyak MA, Meller S, Cerione RA. An Essential Role for Cdc42 in the Functioning of the Adult Mammary Gland. The Journal of Biological Chemistry. PMID 26912661 DOI: 10.1074/Jbc.M115.694349  1
2016 Singh G, Zhang J, Ma Y, Cerione RA, Antonyak MA. The Different Conformational States of Tissue Transglutaminase Have Opposing Affects on Cell Viability. The Journal of Biological Chemistry. PMID 26893378 DOI: 10.1074/Jbc.M115.699108  1
2016 Lukey MJ, Cerione RA. The regulation of cancer cell glutamine metabolism Translational Cancer Research. 5. DOI: 10.21037/10459  1
2015 Bordeleau F, Chan B, Antonyak MA, Lampi MC, Cerione RA, Reinhart-King CA. Microvesicles released from tumor cells disrupt epithelial cell morphology and contractility. Journal of Biomechanics. PMID 26477404 DOI: 10.1016/J.Jbiomech.2015.10.003  0.4
2015 Katt WP, Cerione RA. Less than the sum of its parts, a leinamycin precursor has superior properties. Proceedings of the National Academy of Sciences of the United States of America. PMID 26106161 DOI: 10.1073/Pnas.1510122112  1
2015 Choi HW, Tian M, Song F, Venereau E, Preti A, Park SW, Hamilton K, Swapna GV, Manohar M, Moreau M, Agresti A, Gorzanelli A, De Marchis F, Wang H, Antonyak M, ... ... Cerione RA, et al. Aspirin's Active Metabolite Salicylic Acid Targets High Mobility Group Box 1 to Modulate Inflammatory Responses. Molecular Medicine (Cambridge, Mass.). PMID 26101955 DOI: 10.2119/Molmed.2015.00148  0.4
2015 Antonyak MA, Cerione RA. Emerging picture of the distinct traits and functions of microvesicles and exosomes. Proceedings of the National Academy of Sciences of the United States of America. 112: 3589-90. PMID 25762069 DOI: 10.1073/Pnas.1502590112  1
2015 Stalnecker CA, Ulrich SM, Li Y, Ramachandran S, McBrayer MK, DeBerardinis RJ, Cerione RA, Erickson JW. Mechanism by which a recently discovered allosteric inhibitor blocks glutamine metabolism in transformed cells. Proceedings of the National Academy of Sciences of the United States of America. 112: 394-9. PMID 25548170 DOI: 10.1073/Pnas.1414056112  1
2015 Katt WP, Antonyak MA, Cerione RA. Simultaneously targeting tissue transglutaminase and kidney type glutaminase sensitizes cancer cells to acid toxicity and offers new opportunities for therapeutic intervention. Molecular Pharmaceutics. 12: 46-55. PMID 25426679 DOI: 10.1021/Mp500405H  1
2015 Kreger BT, Antonyak M, Cerione R. Abstract LB-025: Survivin is trafficked into cancer cell-derived exosomes via a microtubule-dependent mechanism Cancer Research. 75. DOI: 10.1158/1538-7445.Am2015-Lb-025  0.48
2014 Santana SM, Antonyak MA, Cerione RA, Kirby BJ. Cancerous epithelial cell lines shed extracellular vesicles with a bimodal size distribution that is sensitive to glutamine inhibition. Physical Biology. 11: 065001. PMID 25426818 DOI: 10.1088/1478-3975/11/6/065001  1
2014 Santana SM, Antonyak MA, Cerione RA, Kirby BJ. Microfluidic isolation of cancer-cell-derived microvesicles from hetergeneous extracellular shed vesicle populations. Biomedical Microdevices. 16: 869-77. PMID 25342569 DOI: 10.1007/S10544-014-9891-Z  1
2014 Antonyak MA, Cerione RA. Microvesicles as mediators of intercellular communication in cancer. Methods in Molecular Biology (Clifton, N.J.). 1165: 147-73. PMID 24839024 DOI: 10.1007/978-1-4939-0856-1_11  1
2014 Salamanca HH, Antonyak MA, Cerione RA, Shi H, Lis JT. Inhibiting heat shock factor 1 in human cancer cells with a potent RNA aptamer. Plos One. 9: e96330. PMID 24800749 DOI: 10.1371/Journal.Pone.0096330  1
2014 Lin MC, Rojas KS, Cerione RA, Wilson KF. Identification of mTORC2 as a necessary component of HRG/ErbB2-dependent cellular transformation. Molecular Cancer Research : McR. 12: 940-52. PMID 24615340 DOI: 10.1158/1541-7786.Mcr-13-0555  1
2014 Boroughs LK, Antonyak MA, Cerione RA. A novel mechanism by which tissue transglutaminase activates signaling events that promote cell survival. The Journal of Biological Chemistry. 289: 10115-25. PMID 24569994 DOI: 10.1074/jbc.M113.464693  1
2014 Katt WP, Cerione RA. Glutaminase regulation in cancer cells: a druggable chain of events. Drug Discovery Today. 19: 450-7. PMID 24140288 DOI: 10.1016/J.Drudis.2013.10.008  1
2014 Erickson JW, Antonyak MA, Fuji R, Cerione RA. Rho GTPases in cancer Ras Superfamily Small G Proteins: Biology and Mechanisms 1: General Features, Signaling. 421-438. DOI: 10.1007/978-3-7091-1806-1_18  1
2013 Bryant KL, Antonyak MA, Cerione RA, Baird B, Holowka D. Mutations in the polybasic juxtamembrane sequence of both plasma membrane- and endoplasmic reticulum-localized epidermal growth factor receptors confer ligand-independent cell transformation. The Journal of Biological Chemistry. 288: 34930-42. PMID 24142702 DOI: 10.1074/Jbc.M113.513333  1
2013 Møller M, Nielsen SS, Ramachandran S, Li Y, Li Y, Tria G, Streicher W, Petoukhov MV, Cerione RA, Gillilan RE, Vestergaard B. Small angle X-ray scattering studies of mitochondrial glutaminase C reveal extended flexible regions, and link oligomeric state with enzyme activity. Plos One. 8: e74783. PMID 24098668 DOI: 10.1371/Journal.Pone.0074783  1
2013 Lukey MJ, Wilson KF, Cerione RA. Therapeutic strategies impacting cancer cell glutamine metabolism. Future Medicinal Chemistry. 5: 1685-700. PMID 24047273 DOI: 10.4155/Fmc.13.130  1
2013 Jin Y, Liu Y, Lin Q, Li J, Druso JE, Antonyak MA, Meininger CJ, Zhang SL, Dostal DE, Guan JL, Cerione RA, Peng X. Deletion of Cdc42 enhances ADAM17-mediated vascular endothelial growth factor receptor 2 shedding and impairs vascular endothelial cell survival and vasculogenesis. Molecular and Cellular Biology. 33: 4181-97. PMID 23979594 DOI: 10.1128/Mcb.00650-13  1
2013 Zhang J, Antonyak MA, Singh G, Cerione RA. A mechanism for the upregulation of EGF receptor levels in glioblastomas. Cell Reports. 3: 2008-20. PMID 23770238 DOI: 10.1016/j.celrep.2013.05.021  1
2013 Zhou Y, Johnson JL, Cerione RA, Erickson JW. Prenylation and membrane localization of Cdc42 are essential for activation by DOCK7. Biochemistry. 52: 4354-63. PMID 23718289 DOI: 10.1021/Bi301688G  1
2013 Freisinger T, Klünder B, Johnson J, Müller N, Pichler G, Beck G, Costanzo M, Boone C, Cerione RA, Frey E, Wedlich-Söldner R. Establishment of a robust single axis of cell polarity by coupling multiple positive feedback loops. Nature Communications. 4: 1807. PMID 23651995 DOI: 10.1038/Ncomms2795  1
2013 Jeong SM, Xiao C, Finley LW, Lahusen T, Souza AL, Pierce K, Li YH, Wang X, Laurent G, German NJ, Xu X, Li C, Wang RH, Lee J, Csibi A, ... Cerione R, et al. SIRT4 has tumor-suppressive activity and regulates the cellular metabolic response to DNA damage by inhibiting mitochondrial glutamine metabolism. Cancer Cell. 23: 450-63. PMID 23562301 DOI: 10.1016/J.Ccr.2013.02.024  1
2013 Wilson KF, Erickson JW, Antonyak MA, Cerione RA. Rho GTPases and their roles in cancer metabolism. Trends in Molecular Medicine. 19: 74-82. PMID 23219172 DOI: 10.1016/j.molmed.2012.10.011  1
2013 Peng X, Lin Q, Liu Y, Jin Y, Druso JE, Antonyak MA, Guan JL, Cerione RA. Inactivation of Cdc42 in embryonic brain results in hydrocephalus with ependymal cell defects in mice. Protein & Cell. 4: 231-42. PMID 23150167 DOI: 10.1007/S13238-012-2098-2  1
2013 Santana SM, Antonyak MA, Fischbach-Teschl C, Cerione RA, Kirby BJ. Novel microfluidic platforms for the interrogation of patient-derived CTCs and tumor-derived microvesicles 17th International Conference On Miniaturized Systems For Chemistry and Life Sciences, Microtas 2013. 3: 1665-1667.  1
2012 Antonyak MA, Wilson KF, Cerione RA. R(h)oads to microvesicles. Small Gtpases. 3: 219-24. PMID 22906997 DOI: 10.4161/Sgtp.20755  1
2012 Yoo SM, Antonyak MA, Cerione RA. The adaptor protein and Arf GTPase-activating protein Cat-1/Git-1 is required for cellular transformation. The Journal of Biological Chemistry. 287: 31462-70. PMID 22807447 DOI: 10.1074/Jbc.M112.353615  1
2012 Zhou Y, Zhang H, He B, Du J, Lin H, Cerione RA, Hao Q. The bicyclic intermediate structure provides insights into the desuccinylation mechanism of human sirtuin 5 (SIRT5). The Journal of Biological Chemistry. 287: 28307-14. PMID 22767592 DOI: 10.1074/Jbc.M112.384511  1
2012 Milano SK, Kwon W, Pereira R, Antonyak MA, Cerione RA. Characterization of a novel activated Ran GTPase mutant and its ability to induce cellular transformation. The Journal of Biological Chemistry. 287: 24955-66. PMID 22679017 DOI: 10.1074/Jbc.M111.306514  1
2012 Basso M, Berlin J, Xia L, Sleiman SF, Ko B, Haskew-Layton R, Kim E, Antonyak MA, Cerione RA, Iismaa SE, Willis D, Cho S, Ratan RR. Transglutaminase inhibition protects against oxidative stress-induced neuronal death downstream of pathological ERK activation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 6561-9. PMID 22573678 DOI: 10.1523/Jneurosci.3353-11.2012  1
2012 Katt WP, Ramachandran S, Erickson JW, Cerione RA. Dibenzophenanthridines as inhibitors of glutaminase C and cancer cell proliferation. Molecular Cancer Therapeutics. 11: 1269-78. PMID 22496480 DOI: 10.1158/1535-7163.Mct-11-0942  1
2012 Singh G, Ramachandran S, Cerione RA. A constitutively active Gα subunit provides insights into the mechanism of G protein activation. Biochemistry. 51: 3232-40. PMID 22448927 DOI: 10.1021/Bi3001984  1
2012 Li B, Antonyak MA, Zhang J, Cerione RA. RhoA triggers a specific signaling pathway that generates transforming microvesicles in cancer cells. Oncogene. 31: 4740-9. PMID 22266864 DOI: 10.1038/onc.2011.636  1
2012 Johnson JL, Erickson JW, Cerione RA. C-terminal di-arginine motif of Cdc42 protein is essential for binding to phosphatidylinositol 4,5-bisphosphate-containing membranes and inducing cellular transformation. The Journal of Biological Chemistry. 287: 5764-74. PMID 22215673 DOI: 10.1074/jbc.M111.336487  1
2012 Johnson J, Cerione RA, Erickson JW. A quantitative fluorometric approach for measuring the interaction of RhoGDI with membranes and Rho GTPases. Methods in Molecular Biology (Clifton, N.J.). 827: 107-19. PMID 22144271 DOI: 10.1007/978-1-61779-442-1_8  1
2011 Li B, Cerione RA, Antonyak M. Tissue transglutaminase and its role in human cancer progression. Advances in Enzymology and Related Areas of Molecular Biology. 78: 247-93. PMID 22220476 DOI: 10.1002/9781118105771.Ch6  1
2011 Du J, Zhou Y, Su X, Yu JJ, Khan S, Jiang H, Kim J, Woo J, Kim JH, Choi BH, He B, Chen W, Zhang S, Cerione RA, Auwerx J, et al. Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase. Science (New York, N.Y.). 334: 806-9. PMID 22076378 DOI: 10.1126/Science.1207861  1
2011 Boroughs LK, Antonyak MA, Johnson JL, Cerione RA. A unique role for heat shock protein 70 and its binding partner tissue transglutaminase in cancer cell migration. The Journal of Biological Chemistry. 286: 37094-107. PMID 21896482 DOI: 10.1074/Jbc.M111.242438  1
2011 Antonyak MA, Li B, Boroughs LK, Johnson JL, Druso JE, Bryant KL, Holowka DA, Cerione RA. Cancer cell-derived microvesicles induce transformation by transferring tissue transglutaminase and fibronectin to recipient cells. Proceedings of the National Academy of Sciences of the United States of America. 108: 4852-7. PMID 21368175 DOI: 10.1073/pnas.1017667108  1
2011 Ramachandran S, Cerione RA. A dominant-negative Galpha mutant that traps a stable rhodopsin-Galpha-GTP-betagamma complex. The Journal of Biological Chemistry. 286: 12702-11. PMID 21285355 DOI: 10.1074/Jbc.M110.166538  1
2011 Englich U, Kriksunov IA, Cerione RA, Cook MJ, Gillilan R, Gruner SM, Huang Q, Kim CU, Miller W, Nielsen S, Schuller D, Smith S, Szebenyi DM. Microcrystallography, high-pressure cryocooling and BioSAXS at MacCHESS. Journal of Synchrotron Radiation. 18: 70-3. PMID 21169696 DOI: 10.1107/S0909049510036010  1
2011 Wu X, Ramachandran S, Lin MC, Cerione RA, Erickson JW. A minimal Rac activation domain in the unconventional guanine nucleotide exchange factor Dock180. Biochemistry. 50: 1070-80. PMID 21033699 DOI: 10.1021/Bi100971Y  1
2011 Antonyak MA, Li B, Boroughs LK, Johnson JL, Druso JE, Bryant KL, Holowka DA, Cerione RA. Cancer cell-derived microvesicles induce transformation by transferring tissue transglutaminase and fibronectin to recipient cells (Proceedings of the National Academy of Sciences of the United States of America (2011) 108, 12, (4852-4857) DOI: 10.1073/pnas. 1017667108) Proceedings of the National Academy of Sciences of the United States of America. 108: 17569. DOI: 10.1073/pnas.1114824108  1
2010 Dias SM, Cerione RA, Wilson KF. Unloading RNAs in the cytoplasm: an "importin" task. Nucleus (Austin, Tex.). 1: 139-43. PMID 21326945 DOI: 10.4161/Nucl.1.2.10919  1
2010 Erickson JW, Cerione RA. Glutaminase: a hot spot for regulation of cancer cell metabolism? Oncotarget. 1: 734-40. PMID 21234284  1
2010 Wang JB, Erickson JW, Fuji R, Ramachandran S, Gao P, Dinavahi R, Wilson KF, Ambrosio AL, Dias SM, Dang CV, Cerione RA. Targeting mitochondrial glutaminase activity inhibits oncogenic transformation. Cancer Cell. 18: 207-19. PMID 20832749 DOI: 10.1016/J.Ccr.2010.08.009  1
2010 McConoughey SJ, Basso M, Niatsetskaya ZV, Sleiman SF, Smirnova NA, Langley BC, Mahishi L, Cooper AJ, Antonyak MA, Cerione RA, Li B, Starkov A, Chaturvedi RK, Beal MF, Coppola G, et al. Inhibition of transglutaminase 2 mitigates transcriptional dysregulation in models of Huntington disease. Embo Molecular Medicine. 2: 349-70. PMID 20665636 DOI: 10.1002/Emmm.201000084  1
2010 Feng Q, Baird D, Yoo S, Antonyak M, Cerione RA. Phosphorylation of the cool-1/beta-Pix protein serves as a regulatory signal for the migration and invasive activity of Src-transformed cells. The Journal of Biological Chemistry. 285: 18806-16. PMID 20375009 DOI: 10.1074/Jbc.M109.098079  1
2010 Li B, Antonyak MA, Druso JE, Cheng L, Nikitin AY, Cerione RA. EGF potentiated oncogenesis requires a tissue transglutaminase-dependent signaling pathway leading to Src activation. Proceedings of the National Academy of Sciences of the United States of America. 107: 1408-13. PMID 20080707 DOI: 10.1073/Pnas.0907907107  1
2010 Ly TK, Wang J, Pereira R, Rojas KS, Peng X, Feng Q, Cerione RA, Wilson KF. Activation of the Ran GTPase is subject to growth factor regulation and can give rise to cellular transformation. The Journal of Biological Chemistry. 285: 5815-26. PMID 20028979 DOI: 10.1074/Jbc.M109.071886  1
2010 Wang JB, Erickson JW, Fuji R, Ramachandran S, Gao P, Dinavahi R, Wilson KF, Ambrosio ALB, Dias SMG, Dang CV, Cerione RA. Targeting mitochondrial glutaminase activity inhibits oncogenic transformation Cancer Cell. 18: 397. DOI: 10.1016/j.ccr.2010.10.011  1
2010 Antonyak M, Cerione RA. Tissue transglutaminase. a unique GTP-binding/GTPase Handbook of Cell Signaling, 2/E. 2: 1795-1802. DOI: 10.1016/B978-0-12-374145-5.00219-9  1
2010 Feng Q, Cerione RA. Cdc42 and its cellular functions Handbook of Cell Signaling, 2/E. 2: 1785-1794. DOI: 10.1016/B978-0-12-374145-5.00218-7  1
2009 Dias SM, Wilson KF, Rojas KS, Ambrosio AL, Cerione RA. The molecular basis for the regulation of the cap-binding complex by the importins. Nature Structural & Molecular Biology. 16: 930-7. PMID 19668212 DOI: 10.1038/nsmb.1649  1
2009 Antonyak MA, Cerione RA. Ras and the FAK paradox. Molecular Cell. 35: 141-2. PMID 19647511 DOI: 10.1016/J.Molcel.2009.07.005  1
2009 Johnson JL, Erickson JW, Cerione RA. New insights into how the Rho guanine nucleotide dissociation inhibitor regulates the interaction of Cdc42 with membranes. The Journal of Biological Chemistry. 284: 23860-71. PMID 19581296 DOI: 10.1074/Jbc.M109.031815  1
2009 Antonyak MA, Li B, Regan AD, Feng Q, Dusaban SS, Cerione RA. Tissue transglutaminase is an essential participant in the epidermal growth factor-stimulated signaling pathway leading to cancer cell migration and invasion. The Journal of Biological Chemistry. 284: 17914-25. PMID 19403524 DOI: 10.1074/Jbc.M109.013037  1
2009 Endo M, Antonyak MA, Cerione RA. Cdc42-mTOR signaling pathway controls Hes5 and Pax6 expression in retinoic acid-dependent neural differentiation. The Journal of Biological Chemistry. 284: 5107-18. PMID 19097998 DOI: 10.1074/jbc.M807745200  1
2008 Peng X, Wu X, Druso JE, Wei H, Park AY, Kraus MS, Alcaraz A, Chen J, Chien S, Cerione RA, Guan JL. Cardiac developmental defects and eccentric right ventricular hypertrophy in cardiomyocyte focal adhesion kinase (FAK) conditional knockout mice. Proceedings of the National Academy of Sciences of the United States of America. 105: 6638-43. PMID 18448675 DOI: 10.1073/Pnas.0802319105  1
2008 Phillips MJ, Calero G, Chan B, Ramachandran S, Cerione RA. Effector proteins exert an important influence on the signaling-active state of the small GTPase Cdc42. The Journal of Biological Chemistry. 283: 14153-64. PMID 18348980 DOI: 10.1074/Jbc.M706271200  1
2008 DeRegis CJ, Rahl PB, Hoffman GR, Cerione RA, Collins RN. Mutational analysis of betaCOP (Sec26p) identifies an appendage domain critical for function. Bmc Cell Biology. 9: 3. PMID 18211691 DOI: 10.1186/1471-2121-9-3  1
2008 Erickson JW, Cerione RA. A new tool for G protein analysis. Acs Chemical Biology. 3: 24-6. PMID 18205289 DOI: 10.1021/Cb700239D  1
2007 Datta S, Antonyak MA, Cerione RA. GTP-binding-defective forms of tissue transglutaminase trigger cell death. Biochemistry. 46: 14819-29. PMID 18052077 DOI: 10.1021/Bi701422H  1
2007 Casey FP, Baird D, Feng Q, Gutenkunst RN, Waterfall JJ, Myers CR, Brown KS, Cerione RA, Sethna JP. Optimal experimental design in an epidermal growth factor receptor signalling and down-regulation model. Iet Systems Biology. 1: 190-202. PMID 17591178 DOI: 10.1049/Iet-Syb:20060065  1
2007 Dias SM, Cerione RA. X-ray crystal structures reveal two activated states for RhoC. Biochemistry. 46: 6547-58. PMID 17497936 DOI: 10.1021/Bi700035P  1
2006 Antonyak MA, Jansen JM, Miller AM, Ly TK, Endo M, Cerione RA. Two isoforms of tissue transglutaminase mediate opposing cellular fates. Proceedings of the National Academy of Sciences of the United States of America. 103: 18609-14. PMID 17116873 DOI: 10.1073/Pnas.0604844103  1
2006 Datta S, Antonyak MA, Cerione RA. Importance of Ca(2+)-dependent transamidation activity in the protection afforded by tissue transglutaminase against doxorubicin-induced apoptosis. Biochemistry. 45: 13163-74. PMID 17073438 DOI: 10.1021/Bi0606795  1
2006 Lin Q, Yang W, Baird D, Feng Q, Cerione RA. Identification of a DOCK180-related guanine nucleotide exchange factor that is capable of mediating a positive feedback activation of Cdc42. The Journal of Biological Chemistry. 281: 35253-62. PMID 16968698 DOI: 10.1074/Jbc.M606248200  1
2006 Ramachandran S, Cerione RA. How GPCRs hit the switch. Nature Structural & Molecular Biology. 13: 756-7. PMID 16955094 DOI: 10.1038/Nsmb0906-756  1
2006 Feng Q, Baird D, Peng X, Wang J, Ly T, Guan JL, Cerione RA. Cool-1 functions as an essential regulatory node for EGF receptor- and Src-mediated cell growth. Nature Cell Biology. 8: 945-56. PMID 16892055 DOI: 10.1038/Ncb1453  1
2006 Fidyk N, Wang JB, Cerione RA. Influencing cellular transformation by modulating the rates of GTP hydrolysis by Cdc42. Biochemistry. 45: 7750-62. PMID 16784226 DOI: 10.1021/Bi060365H  1
2006 Wakshlag JJ, Antonyak MA, Boehm JE, Boehm K, Cerione RA. Effects of tissue transglutaminase on beta -amyloid1-42-induced apoptosis. The Protein Journal. 25: 83-94. PMID 16721663 DOI: 10.1007/S10930-006-0009-1  1
2006 Wakshlag JJ, McNeill CJ, Antonyak MA, Boehm JE, Fuji R, Balkman CE, Zgola M, Cerione RA, Page RL. Expression and activity of transglutaminase II in spontaneous tumours of dogs and cats. Journal of Comparative Pathology. 134: 202-10. PMID 16615935 DOI: 10.1016/J.Jcpa.2005.11.001  1
2006 Lin Q, Yang W, Cerione RA. Measurement of epidermal growth factor receptor turnover and effects of Cdc42. Methods in Enzymology. 406: 614-25. PMID 16472692 DOI: 10.1016/S0076-6879(06)06048-4  1
2006 Majumdar S, Ramachandran S, Cerione RA. New insights into the role of conserved, essential residues in the GTP binding/GTP hydrolytic cycle of large G proteins. The Journal of Biological Chemistry. 281: 9219-26. PMID 16469737 DOI: 10.1074/Jbc.M513837200  1
2005 Smith WJ, Hamel B, Yohe ME, Sondek J, Cerione RA, Snyder JT. A Cdc42 mutant specifically activated by intersectin. Biochemistry. 44: 13282-90. PMID 16201754 DOI: 10.1021/Bi050591B  1
2005 Pereira R, Cerione RA. A switch 3 point mutation in the alpha subunit of transducin yields a unique dominant-negative inhibitor. The Journal of Biological Chemistry. 280: 35696-703. PMID 16103122 DOI: 10.1074/Jbc.M504935200  1
2005 Wang JB, Wu WJ, Cerione RA. Cdc42 and Ras cooperate to mediate cellular transformation by intersectin-L. The Journal of Biological Chemistry. 280: 22883-91. PMID 15824104 DOI: 10.1074/Jbc.M414375200  1
2005 Baird D, Feng Q, Cerione RA. The Cool-2/alpha-Pix protein mediates a Cdc42-Rac signaling cascade. Current Biology : Cb. 15: 1-10. PMID 15649357 DOI: 10.1016/J.Cub.2004.12.040  1
2004 Brown KS, Hill CC, Calero GA, Myers CR, Lee KH, Sethna JP, Cerione RA. The statistical mechanics of complex signaling networks: nerve growth factor signaling. Physical Biology. 1: 184-95. PMID 16204838 DOI: 10.1088/1478-3967/1/3/006  1
2004 Feng Q, Baird D, Cerione RA. Novel regulatory mechanisms for the Dbl family guanine nucleotide exchange factor Cool-2/alpha-Pix. The Embo Journal. 23: 3492-504. PMID 15306850 DOI: 10.1038/Sj.Emboj.7600331  1
2004 Antonyak MA, Miller AM, Jansen JM, Boehm JE, Balkman CE, Wakshlag JJ, Page RL, Cerione RA. Augmentation of tissue transglutaminase expression and activation by epidermal growth factor inhibit doxorubicin-induced apoptosis in human breast cancer cells. The Journal of Biological Chemistry. 279: 41461-7. PMID 15272014 DOI: 10.1074/Jbc.M404976200  1
2004 Majumdar S, Ramachandran S, Cerione RA. Perturbing the linker regions of the alpha-subunit of transducin: a new class of constitutively active GTP-binding proteins. The Journal of Biological Chemistry. 279: 40137-45. PMID 15271992 DOI: 10.1074/Jbc.M405420200  1
2004 Ramachandran S, Cerione RA. Stabilization of an intermediate activation state for transducin by a fluorescent GTP analogue. Biochemistry. 43: 8778-86. PMID 15236586 DOI: 10.1021/Bi0362774  1
2004 Yang W, Jansen JM, Lin Q, Canova S, Cerione RA, Childress C. Interaction of activated Cdc42-associated tyrosine kinase ACK2 with HSP90. The Biochemical Journal. 382: 199-204. PMID 15144235 DOI: 10.1042/Bj20040623  1
2004 Fortier LA, Deak MM, Semevolos SA, Cerione RA. Insulin-like growth factor-I diminishes the activation status and expression of the small GTPase Cdc42 in articular chondrocytes. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 22: 436-45. PMID 15013107 DOI: 10.1016/J.Orthres.2003.08.021  1
2004 Cerione RA. Cdc42: new roads to travel. Trends in Cell Biology. 14: 127-32. PMID 15003621 DOI: 10.1016/J.Tcb.2004.01.008  1
2004 Erickson JW, Cerione RA. Structural elements, mechanism, and evolutionary convergence of Rho protein-guanine nucleotide exchange factor complexes. Biochemistry. 43: 837-42. PMID 14744125 DOI: 10.1021/Bi036026V  1
2003 Hoffman GR, Rahl PB, Collins RN, Cerione RA. Conserved structural motifs in intracellular trafficking pathways: structure of the gammaCOP appendage domain. Molecular Cell. 12: 615-25. PMID 14527408 DOI: 10.1016/J.Molcel.2003.08.002  1
2003 Tu S, Wu WJ, Wang J, Cerione RA. Epidermal growth factor-dependent regulation of Cdc42 is mediated by the Src tyrosine kinase. The Journal of Biological Chemistry. 278: 49293-300. PMID 14506284 DOI: 10.1074/Jbc.M307021200  1
2003 Wu WJ, Tu S, Cerione RA. Activated Cdc42 sequesters c-Cbl and prevents EGF receptor degradation. Cell. 114: 715-25. PMID 14505571 DOI: 10.1016/S0092-8674(03)00688-3  1
2003 Lin Q, Fuji RN, Yang W, Cerione RA. RhoGDI is required for Cdc42-mediated cellular transformation. Current Biology : Cb. 13: 1469-79. PMID 12956948 DOI: 10.1016/S0960-9822(03)00613-4  1
2003 Flanders JA, Feng Q, Bagrodia S, Laux MT, Singavarapu A, Cerione RA. The Cbl proteins are binding partners for the Cool/Pix family of p21-activated kinase-binding proteins. Febs Letters. 550: 119-23. PMID 12935897 DOI: 10.1016/S0014-5793(03)00853-6  1
2003 Antonyak MA, McNeill CJ, Wakshlag JJ, Boehm JE, Cerione RA. Activation of the Ras-ERK pathway inhibits retinoic acid-induced stimulation of tissue transglutaminase expression in NIH3T3 cells. The Journal of Biological Chemistry. 278: 15859-66. PMID 12604597 DOI: 10.1074/Jbc.M300037200  1
2003 Smith WJ, Nassar N, Bretscher A, Cerione RA, Karplus PA. Structure of the active N-terminal domain of Ezrin. Conformational and mobility changes identify keystone interactions. The Journal of Biological Chemistry. 278: 4949-56. PMID 12429733 DOI: 10.1074/Jbc.M210601200  1
2002 Fidyk NJ, Cerione RA. Understanding the catalytic mechanism of GTPase-activating proteins: demonstration of the importance of switch domain stabilization in the stimulation of GTP hydrolysis. Biochemistry. 41: 15644-53. PMID 12501193 DOI: 10.1021/Bi026413P  1
2002 Osman MA, Konopka JB, Cerione RA. Iqg1p links spatial and secretion landmarks to polarity and cytokinesis. The Journal of Cell Biology. 159: 601-11. PMID 12446742 DOI: 10.1083/Jcb.200205084  1
2002 Calero G, Wilson KF, Ly T, Rios-Steiner JL, Clardy JC, Cerione RA. Structural basis of m7GpppG binding to the nuclear cap-binding protein complex. Nature Structural Biology. 9: 912-7. PMID 12434151 DOI: 10.1038/Nsb874  1
2002 Tu SS, Wu WJ, Yang W, Nolbant P, Hahn K, Cerione RA. Antiapoptotic Cdc42 mutants are potent activators of cellular transformation. Biochemistry. 41: 12350-8. PMID 12369824 DOI: 10.1021/Bi026167H  1
2002 Smith WJ, Cerione RA. Crystallization and preliminary crystallographic analysis of the ezrin FERM domain. Acta Crystallographica. Section D, Biological Crystallography. 58: 1359-61. PMID 12136155 DOI: 10.1107/S0907444902010004  1
2002 Daniel S, Noda M, Cerione RA, Sharp GW. A link between Cdc42 and syntaxin is involved in mastoparan-stimulated insulin release. Biochemistry. 41: 9663-71. PMID 12135388 DOI: 10.1021/Bi025604P  1
2002 Boehm JE, Singh U, Combs C, Antonyak MA, Cerione RA. Tissue transglutaminase protects against apoptosis by modifying the tumor suppressor protein p110 Rb. The Journal of Biological Chemistry. 277: 20127-30. PMID 11956182 DOI: 10.1074/jbc.C200147200  1
2002 Hoffman GR, Cerione RA. Signaling to the Rho GTPases: networking with the DH domain. Febs Letters. 513: 85-91. PMID 11911885 DOI: 10.1016/S0014-5793(01)03310-5  1
2002 Liu S, Cerione RA, Clardy J. Structural basis for the guanine nucleotide-binding activity of tissue transglutaminase and its regulation of transamidation activity. Proceedings of the National Academy of Sciences of the United States of America. 99: 2743-7. PMID 11867708 DOI: 10.1073/Pnas.042454899  1
2002 Antonyak MA, Boehm JE, Cerione RA. Phosphoinositide 3-kinase activity is required for retinoic acid-induced expression and activation of the tissue transglutaminase. The Journal of Biological Chemistry. 277: 14712-6. PMID 11854287 DOI: 10.1074/Jbc.M112259200  1
2002 Lin Q, Lo CG, Cerione RA, Yang W. The Cdc42 target ACK2 interacts with sorting nexin 9 (SH3PX1) to regulate epidermal growth factor receptor degradation. The Journal of Biological Chemistry. 277: 10134-8. PMID 11799118 DOI: 10.1074/Jbc.M110329200  1
2002 Feng Q, Albeck JG, Cerione RA, Yang W. Regulation of the Cool/Pix proteins: key binding partners of the Cdc42/Rac targets, the p21-activated kinases. The Journal of Biological Chemistry. 277: 5644-50. PMID 11741931 DOI: 10.1074/Jbc.M107704200  1
2001 Yang W, Lin Q, Zhao J, Guan JL, Cerione RA. The nonreceptor tyrosine kinase ACK2, a specific target for Cdc42 and a negative regulator of cell growth and focal adhesion complexes. The Journal of Biological Chemistry. 276: 43987-93. PMID 11535592 DOI: 10.1074/Jbc.M104819200  1
2001 Antonyak MA, Singh US, Lee DA, Boehm JE, Combs C, Zgola MM, Page RL, Cerione RA. Effects of tissue transglutaminase on retinoic acid-induced cellular differentiation and protection against apoptosis. The Journal of Biological Chemistry. 276: 33582-7. PMID 11438548 DOI: 10.1074/jbc.M105318200  1
2001 Yang W, Lo CG, Dispenza T, Cerione RA. The Cdc42 target ACK2 directly interacts with clathrin and influences clathrin assembly. The Journal of Biological Chemistry. 276: 17468-73. PMID 11278777 DOI: 10.1074/Jbc.M010893200  1
2001 Tu S, Cerione RA. Cdc42 is a substrate for caspases and influences Fas-induced apoptosis. The Journal of Biological Chemistry. 276: 19656-63. PMID 11278572 DOI: 10.1074/Jbc.M009838200  1
2001 Erickson JW, Cerione RA. Multiple roles for Cdc42 in cell regulation. Current Opinion in Cell Biology. 13: 153-7. PMID 11248548 DOI: 10.1016/S0955-0674(00)00192-7  1
2001 Hoffman GR, Cerione RA. Rac inserts its way into the immune response. Nature Immunology. 2: 194-6. PMID 11224514 DOI: 10.1038/85240  1
2001 Hong-Geller E, Holowka D, Siraganian RP, Baird B, Cerione RA. Activated Cdc42/Rac reconstitutes Fcepsilon RI-mediated Ca2+ mobilization and degranulation in mutant RBL mast cells. Proceedings of the National Academy of Sciences of the United States of America. 98: 1154-9. PMID 11158610 DOI: 10.1073/Pnas.98.3.1154  1
2000 Wilson KF, Wu WJ, Cerione RA. Cdc42 stimulates RNA splicing via the S6 kinase and a novel S6 kinase target, the nuclear cap-binding complex. The Journal of Biological Chemistry. 275: 37307-10. PMID 10973943 DOI: 10.1074/Jbc.C000482200  1
2000 Hoffman GR, Cerione RA. Flipping the switch: the structural basis for signaling through the CRIB motif. Cell. 102: 403-6. PMID 10966102 DOI: 10.1016/S0092-8674(00)00045-3  1
2000 Wilson KF, Cerione RA. Signal transduction and post-transcriptional gene expression. Biological Chemistry. 381: 357-65. PMID 10937866 DOI: 10.1515/BC.2000.048  1
2000 Wu WJ, Erickson JW, Lin R, Cerione RA. The gamma-subunit of the coatomer complex binds Cdc42 to mediate transformation. Nature. 405: 800-4. PMID 10866202 DOI: 10.1038/35015585  1
2000 Walker SJ, Wu WJ, Cerione RA, Brown HA. Activation of phospholipase D1 by Cdc42 requires the Rho insert region. The Journal of Biological Chemistry. 275: 15665-8. PMID 10747870 DOI: 10.1074/jbc.M000076200  1
2000 Hoffman GR, Nassar N, Cerione RA. Structure of the Rho family GTP-binding protein Cdc42 in complex with the multifunctional regulator RhoGDI. Cell. 100: 345-56. PMID 10676816 DOI: 10.1016/S0092-8674(00)80670-4  1
2000 Hong-Geller E, Cerione RA. Cdc42 and Rac stimulate exocytosis of secretory granules by activating the IP(3)/calcium pathway in RBL-2H3 mast cells. The Journal of Cell Biology. 148: 481-94. PMID 10662774 DOI: 10.1083/Jcb.148.3.481  1
1999 Nomanbhoy T, Cerione RA. Fluorescence assays of Cdc42 interactions with target/effector proteins. Biochemistry. 38: 15878-84. PMID 10625453 DOI: 10.1021/Bi9916832  1
1999 Bagrodia S, Cerione RA. Pak to the future. Trends in Cell Biology. 9: 350-5. PMID 10461188 DOI: 10.1016/S0962-8924(99)01618-9  1
1999 Lin R, Cerione RA, Manor D. Specific contributions of the small GTPases Rho, Rac, and Cdc42 to Dbl transformation. The Journal of Biological Chemistry. 274: 23633-41. PMID 10438546 DOI: 10.1074/Jbc.274.33.23633  1
1999 Bagrodia S, Bailey D, Lenard Z, Hart M, Guan JL, Premont RT, Taylor SJ, Cerione RA. A tyrosine-phosphorylated protein that binds to an important regulatory region on the cool family of p21-activated kinase-binding proteins. The Journal of Biological Chemistry. 274: 22393-400. PMID 10428811 DOI: 10.1074/Jbc.274.32.22393  1
1999 Yang W, Cerione RA. Endocytosis: Is dynamin a 'blue collar' or 'white collar' worker? Current Biology : Cb. 9: R511-4. PMID 10421565 DOI: 10.1016/S0960-9822(99)80323-6  1
1999 Chen LM, Bagrodia S, Cerione RA, Galán JE. Requirement of p21-activated kinase (PAK) for Salmonella typhimurium-induced nuclear responses. The Journal of Experimental Medicine. 189: 1479-88. PMID 10224288 DOI: 10.1084/Jem.189.9.1479  1
1999 Yang W, Lin Q, Guan JL, Cerione RA. Activation of the Cdc42-associated tyrosine kinase-2 (ACK-2) by cell adhesion via integrin beta1. The Journal of Biological Chemistry. 274: 8524-30. PMID 10085085 DOI: 10.1074/Jbc.274.13.8524  1
1999 Nomanbhoy TK, Erickson JW, Cerione RA. Kinetics of Cdc42 membrane extraction by Rho-GDI monitored by real-time fluorescence resonance energy transfer. Biochemistry. 38: 1744-50. PMID 10026253 DOI: 10.1021/Bi982198U  1
1999 Wilson KF, Fortes P, Singh US, Ohno M, Mattaj IW, Cerione RA. The nuclear cap-binding complex is a novel target of growth factor receptor-coupled signal transduction. The Journal of Biological Chemistry. 274: 4166-73. PMID 9933612 DOI: 10.1074/Jbc.274.7.4166  1
1999 Berger AL, Cerione RA, Erickson JW. Delineation of two functionally distinct gammaPDE binding sites on the bovine retinal cGMP phosphodiesterase by a mutant gammaPDE subunit. Biochemistry. 38: 1293-9. PMID 9930990 DOI: 10.1021/Bi981683M  1
1999 Glaven JA, Whitehead I, Bagrodia S, Kay R, Cerione RA. The Dbl-related protein, Lfc, localizes to microtubules and mediates the activation of Rac signaling pathways in cells. The Journal of Biological Chemistry. 274: 2279-85. PMID 9890991 DOI: 10.1074/jbc.274.4.2279  1
1998 Nassar N, Hoffman GR, Manor D, Clardy JC, Cerione RA. Structures of Cdc42 bound to the active and catalytically compromised forms of Cdc42GAP. Nature Structural Biology. 5: 1047-52. PMID 9846874 DOI: 10.1038/4156  1
1998 Guo W, Sutcliffe MJ, Cerione RA, Oswald RE. Identification of the binding surface on Cdc42Hs for p21-activated kinase. Biochemistry. 37: 14030-7. PMID 9760238 DOI: 10.1021/bi981352+  1
1998 Allen KM, Gleeson JG, Bagrodia S, Partington MW, MacMillan JC, Cerione RA, Mulley JC, Walsh CA. PAK3 mutation in nonsyndromic X-linked mental retardation. Nature Genetics. 20: 25-30. PMID 9731525 DOI: 10.1038/1675  1
1998 Bagrodia S, Taylor SJ, Jordon KA, Van Aelst L, Cerione RA. A novel regulator of p21-activated kinases. The Journal of Biological Chemistry. 273: 23633-6. PMID 9726964 DOI: 10.1074/jbc.273.37.23633  1
1998 McCallum SJ, Erickson JW, Cerione RA. Characterization of the association of the actin-binding protein, IQGAP, and activated Cdc42 with Golgi membranes. The Journal of Biological Chemistry. 273: 22537-44. PMID 9712880 DOI: 10.1074/Jbc.273.35.22537  1
1998 Osman MA, Cerione RA. Iqg1p, a yeast homologue of the mammalian IQGAPs, mediates cdc42p effects on the actin cytoskeleton. The Journal of Cell Biology. 142: 443-55. PMID 9679143 DOI: 10.1083/Jcb.142.2.443  1
1998 Nomanbhoy T, Cerione RA. Use of fluorescence spectroscopy to study the regulation of small G proteins. Methods in Molecular Biology (Clifton, N.J.). 84: 237-47. PMID 9666453 DOI: 10.1385/0-89603-488-7:237  1
1998 Wu WJ, Lin R, Cerione RA, Manor D. Transformation activity of Cdc42 requires a region unique to Rho- related proteins Journal of Biological Chemistry. 273: 16655-16658. PMID 9642217 DOI: 10.1074/Jbc.273.27.16655  1
1998 Leonard DA, Lin R, Cerione RA, Manor D. Biochemical studies of the mechanism of action of the Cdc42-GTPase- activating protein Journal of Biological Chemistry. 273: 16210-16215. PMID 9632678 DOI: 10.1074/Jbc.273.26.16210  1
1998 Hoffman GR, Nassar N, Oswald RE, Cerione RA. Fluoride activation of the Rho family GTP-binding protein Cdc42Hs. The Journal of Biological Chemistry. 273: 4392-9. PMID 9468490 DOI: 10.1074/Jbc.273.8.4392  1
1998 Singh US, Li Q, Cerione R. Identification of the eukaryotic initiation factor 5A as a retinoic acid-stimulated cellular binding partner for tissue transglutaminase II. The Journal of Biological Chemistry. 273: 1946-50. PMID 9442029 DOI: 10.1074/Jbc.273.4.1946  0.32
1997 Wu WJ, Leonard DA, Cerione RA, Manor D. Interaction between Cdc42Hs and RhoGDI is mediated through the Rho insert region Journal of Biological Chemistry. 272: 26153-26158. PMID 9334181 DOI: 10.1074/Jbc.272.42.26153  1
1997 Yang W, Cerione RA. Cloning and characterization of a novel Cdc42-associated tyrosine kinase, ACK-2, from bovine brain Journal of Biological Chemistry. 272: 24819-24824. PMID 9312079 DOI: 10.1074/Jbc.272.40.24819  1
1997 Erickson JW, Cerione RA, Hart MJ. Identification of an actin cytoskeletal complex that includes IQGAP and the CDc42 GTPase Journal of Biological Chemistry. 272: 24443-24447. PMID 9305904 DOI: 10.1074/Jbc.272.39.24443  1
1997 Li Q, Cerione RA. Communication between Switch II and Switch III of the transducin α subunit is essential for target activation Journal of Biological Chemistry. 272: 21673-21676. PMID 9268292 DOI: 10.1074/Jbc.272.35.21673  1
1997 Feltham JL, Dötsch V, Raza S, Manor D, Cerione RA, Sutcliffe MJ, Wagner G, Oswald RE. Definition of the switch surface in the solution structure of Cdc42Hs. Biochemistry. 36: 8755-66. PMID 9220962 DOI: 10.1021/Bi970694X  1
1997 Gosser YQ, Nomanbhoy TK, Aghazadeh B, Manor D, Combs C, Cerione RA, Rosen MK. C-terminal binding domain of Rho GDP-dissociation inhibitor directs N-terminal inhibitory peptide to GTPases. Nature. 387: 814-9. PMID 9194563 DOI: 10.1038/42961  1
1997 Gamett DC, Pearson G, Cerione RA, Friedberg I. Secondary dimerization between members of the epidermal growth factor receptor family Journal of Biological Chemistry. 272: 12052-12056. PMID 9115272 DOI: 10.1074/Jbc.272.18.12052  1
1997 Adra CN, Manor D, Ko JL, Zhu S, Horiuchi T, Van Aelst L, Cerione RA, Lim B. RhoGDIgamma: a GDP-dissociation inhibitor for Rho proteins with preferential expression in brain and pancreas. Proceedings of the National Academy of Sciences of the United States of America. 94: 4279-84. PMID 9113980 DOI: 10.1073/Pnas.94.9.4279  1
1997 Leonard DA, Satoskar RS, Wu WJ, Bagrodia S, Cerione RA, Manor D. Use of a fluorescence spectroscopic readout to characterize the interactions of Cdc42Hs with its target/effector, mPAK-3 Biochemistry. 36: 1173-1180. PMID 9033409 DOI: 10.1021/Bi9622837  1
1997 Berger AL, Cerione RA, Erickson JW. Real time conformational changes in the retinal phosphodiesterase γ subunit monitored by resonance energy transfer Journal of Biological Chemistry. 272: 2714-2721. PMID 9006909 DOI: 10.1074/Jbc.272.5.2714  1
1996 Glaven JA, Whitehead IP, Nomanbhoy T, Kay R, Cerione RA. Lfc and Lsc oncoproteins represent two new guanine nucleotide exchange factors for the Rho GTP-binding protein Journal of Biological Chemistry. 271: 27374-27381. PMID 8910315 DOI: 10.1074/Jbc.271.44.27374  1
1996 Singh US, Cerione RA. Biochemical effects of retinoic acid on GTP-binding protein/transglutaminases in HeLa cells: Stimulation of GTP-binding and transglutaminase activity, membrane association, and phosphatidylinositol lipid turnover Journal of Biological Chemistry. 271: 27292-27298. PMID 8910304 DOI: 10.1074/Jbc.271.44.27292  1
1996 Erickson JW, Zhang CJ, Kahn RA, Evans T, Cerione RA. Mammalian Cdc42 is a brefeldin A-sensitive component of the Golgi apparatus Journal of Biological Chemistry. 271: 26850-26854. PMID 8900167 DOI: 10.1074/Jbc.271.43.26850  1
1996 Cerione RA, Zheng Y. The Dbl family of oncogenes Current Opinion in Cell Biology. 8: 216-222. PMID 8791419 DOI: 10.1016/S0955-0674(96)80068-8  1
1996 McCallum SJ, Wu WJ, Cerione RA. Identification of a putative effector for Cdc42Hs with high sequence similarity to the RasGAP-related protein IQGAP1 and a Cdc42Hs binding partner with similarity to IQGAP2 Journal of Biological Chemistry. 271: 21732-21737. PMID 8702968 DOI: 10.1074/Jbc.271.36.21732  1
1996 Zheng Y, Zangrilli D, Cerione RA, Eva A. The pleckstrin homology domain mediates transformation by oncogenic Dbl through specific intracellular targeting Journal of Biological Chemistry. 271: 19017-19020. PMID 8702569 DOI: 10.1074/Jbc.271.32.19017  1
1996 Nomanbhoy TK, Cerione RA. Characterization of the interaction between RhoGDI and Cdc42Hs using fluorescence spectroscopy Journal of Biological Chemistry. 271: 10004-10009. PMID 8626553 DOI: 10.1074/Jbc.271.17.10004  1
1996 Nomanbhoy TK, Leonard DA, Manor D, Cerione RA. Investigation of the GTP-binding/GTPase cycle of Cdc42Hs using extrinsic reporter group fluorescence Biochemistry. 35: 4602-4608. PMID 8605211 DOI: 10.1021/Bi951743D  1
1996 Mittal R, Erickson JW, Cerione RA. Uncoupling of GTP binding from target stimulation by a single mutation in the transducin α subunit Science. 271: 1413-1416. PMID 8596913 DOI: 10.1126/Science.271.5254.1413  1
1995 Zheng Y, Bender A, Cerione RA. Interactions among proteins involved in bud-site selection and bud-site assembly in Saccharomyces cerevisiae Journal of Biological Chemistry. 270: 626-630. PMID 7822288 DOI: 10.1074/Jbc.270.2.626  1
1995 Zheng Y, Olson MF, Hall A, Cerione RA, Toksoz D. Direct involvement of the small GTP-binding protein Rho in lbc oncogene function Journal of Biological Chemistry. 270: 9031-9034. PMID 7721814 DOI: 10.1074/Jbc.270.16.9031  1
1995 Platko JV, Leonard DA, Adra CN, Shaw RJ, Cerione RA, Lim B. A single residue can modify target-binding affinity and activity of the functional domain of the Rho-subfamily GDP dissociation inhibitors Proceedings of the National Academy of Sciences of the United States of America. 92: 2974-2978. PMID 7708758 DOI: 10.1073/Pnas.92.7.2974  1
1995 Gamett DC, Greene T, Wagreich AR, Kim HH, Koland JG, Cerione RA. Heregulin-stimulated signaling in rat pheochromocytoma cells. Evidence for ErbB3 interactions with Neu/ErbB2 and p85 Journal of Biological Chemistry. 270: 19022-19027. PMID 7642563 DOI: 10.1074/Jbc.270.32.19022  1
1995 Cicchetti P, Ridley AJ, Zheng Y, Cerione RA, Baltimore D. 3BP-1, an SH3 domain binding protein, has GAP activity for Rac and inhibits growth factor-induced membrane ruffling in fibroblasts Embo Journal. 14: 3127-3135. PMID 7621827  1
1995 Bagrodia S, Taylor SJ, Creasy CL, Chernoff J, Cerione RA. Identification of a mouse p21Cdc42/Rac activated kinase Journal of Biological Chemistry. 270: 22731-22737. PMID 7559398 DOI: 10.1074/Jbc.270.39.22731  1
1995 Erickson JW, Mittal R, Cerione RA. Use of resonance energy transfer to determine the proximity of the guanine nucleotide binding site of transducin relative to a conformationally-sensitive site on the γ subunit of the cvclic GMP phosnhodiesterase Biochemistry®. 34: 8693-8700. PMID 7542027 DOI: 10.1021/Bi00027A019  1
1995 Bagrodia S, Derijard B, Davis RJ, Cerione RA. Cdc42 and PAK-mediated signaling leads to Jun kinase and p38 mitogen- activated protein kinase activation Journal of Biological Chemistry. 270: 27995-27998. PMID 7499279 DOI: 10.1074/Jbc.270.47.27995  1
1995 Cerione RA, Leonard D, Zheng Y. Purification of baculovirus-expressed Cdc42Hs Methods in Enzymology. 256: 11-15. PMID 7476423 DOI: 10.1016/0076-6879(95)56004-1  1
1995 Singh US, Erickson JW, Cerione RA. Identification and biochemical characterization of an 80 kilodalton GTP-binding/transglutaminase from rabbit liver nuclei Biochemistry. 34: 15863-15871. DOI: 10.1021/Bi00048A032  1
1994 Hart MJ, Eva A, Zangrilli D, Aaronson SA, Evans T, Cerione RA, Zheng Y. Cellular transformation and guanine nucleotide exchange activity are catalyzed by a common domain on the dbl oncogene product Journal of Biological Chemistry. 269: 62-65. PMID 8276860  1
1994 Carraway KL, Sliwkowski MX, Akita R, Platko JV, Guy PM, Nuijens A, John Diamonti A, Vandlen RL, Cantley LC, Cerione RA. The erbB3 gene product is a receptor for heregulin Journal of Biological Chemistry. 269: 14303-14306. PMID 8188716  1
1994 Phillips WJ, Cerione RA. A C-terminal peptide of bovine rhodopsin binds to the transducin α-subunit and facilitates its activation Biochemical Journal. 299: 351-357. PMID 8172594 DOI: 10.1042/Bj2990351  1
1994 Guy PM, Platko JV, Cantley LC, Cerione RA, Carraway KL. Insect cell-expressed p180erbB3 possesses an impaired tyrosine kinase activity Proceedings of the National Academy of Sciences of the United States of America. 91: 8132-8136. PMID 8058768 DOI: 10.1073/Pnas.91.17.8132  1
1994 Zheng Y, Bagrodia S, Cerione RA. Activation of phosphoinositide 3-kinase activity by Cdc42Hs binding to p85 Journal of Biological Chemistry. 269: 18727-18730. PMID 8034624  1
1994 Peterson J, Zheng Y, Bender L, Myers A, Cerione R, Bender A. Interactions between the bud emergence proteins Bem1p and Bem2p and Rho-type GTPases in yeast Journal of Cell Biology. 127: 1395-1406. PMID 7962098 DOI: 10.1083/Jcb.127.5.1395  1
1994 Cerione RA. [31] Fluorescence assays for G-protein interactions Methods in Enzymology. 237: 409-423. PMID 7935014 DOI: 10.1016/S0076-6879(94)37078-8  1
1994 Leonard DA, Evans T, Hart M, Cerione RA, Manor D. Investigation of the GTP-binding/GTPase cycle of Cdc42Hs using fluorescence spectroscopy Biochemistry. 33: 12323-12328. PMID 7918454 DOI: 10.1021/Bi00206A040  1
1994 Gamett DC, Cerione RA. Oncogenically activated or ligand-stimulated neu kinase stimulates neurite outgrowth in PC12 cells Febs Letters. 351: 335-339. PMID 7915994 DOI: 10.1016/0014-5793(94)00855-8  1
1994 Mittal R, Cerione RA, Erickson JW. Aluminum fluoride activation of bovine transducin induces two distinct conformational changes in the alpha subunit. Biochemistry. 33: 10178-10184. PMID 7520280 DOI: 10.1021/Bi00199A046  0.6
1994 Sliwkowski MX, Schaefer G, Akita RW, Lofgren JA, Fitzpatrick VD, Nuijens A, Fendly BM, Cerione RA, Vandlen RL, Carraway KL. Coexpression of erbB2 and er6B3 proteins reconstitutes a high affinity receptor for heregulin Journal of Biological Chemistry. 269: 14661-14665. PMID 7514177  1
1994 Mittal R, Cerione RA, Erickson JW. Aluminum fluoride activation of bovine transducin induces two distinct conformational changes in the α subunit Biochemistry. 33: 10178-10184.  1
1994 Sutcliffe MJ, Feltham J, Cerione RA, Oswald RE. Model building predicts an additional conformational switch when GTP binds to the Cdc42HS protein Protein Pept.Lett.. 1: 84-91.  1
1993 Erickson JW, Cerione RA. Regulation of the cGMP phosphodiesterase in bovine rod outer segments. Use of resonance energy transfer to distinguish between associative and dissociative activation mechanisms Journal of Biological Chemistry. 268: 3328-3333. PMID 8381426  1
1993 Barfod ET, Zheng Y, Kuang WJ, Hart MJ, Evans T, Cerione RA, Ashkenazi A. Cloning and expression of a human CDC42 GTPase-activating protein reveals a functional SH3-binding domain. The Journal of Biological Chemistry. 268: 26059-62. PMID 8253717  1
1993 Zheng Y, Hart MJ, Shinjo K, Evans T, Bender A, Cerione RA. Biochemical comparisons of the Saccharomyces cerevisiae Bem2 and Bem3 proteins: Delineation of a limit Cdc42 GTPase-activating protein domain Journal of Biological Chemistry. 268: 24629-24634. PMID 8227021  1
1993 Carraway KL, Cerione RA. Inhibition of epidermal growth factor receptor aggregation by an antibody directed against the epidermal growth factor receptor extracellular domain Journal of Biological Chemistry. 268: 23860-23867. PMID 8226925  1
1993 Carraway KL, Cerione RA. Fluorescent-labeled growth factor molecules serve as probes for receptor binding and endocytosis Biochemistry. 32: 12039-12045. PMID 8218281 DOI: 10.1021/Bi00096A014  1
1993 Adra CN, Ko J, Leonard D, Wirth LJ, Cerione RA, Lim B. Identification of a novel protein with GDP dissociation inhibitor activity for the ras-like proteins CDC42Hs and rac I Genes Chromosomes and Cancer. 8: 253-261. PMID 7512369 DOI: 10.1002/Gcc.2870080408  1
1992 Phillips WJ, Wong SC, Cerione RA. Rhodopsin/transducin interactions. II. Influence of the transducin-βγ subunit complex on the coupling of the transducin-α subunit to rhodopsin Journal of Biological Chemistry. 267: 17040-17046. PMID 1512243  1
1992 Phillips WJ, Cerione RA. Rhodopsin/transducin interactions. I. Characterization of the binding of the transducin-βγ subunit complex to rhodopsin using fluorescence spectroscopy Journal of Biological Chemistry. 267: 17032-17039. PMID 1512242  1
1992 Hart MJ, Maru Y, Leonard D, Witte ON, Evans T, Cerione RA. A GDP dissociation inhibitor that serves as a GTPase inhibitor for the ras-like protein CDC42HS Science. 258: 812-815. PMID 1439791 DOI: 10.1126/Science.1439791  1
1992 Leonard D, Hart MJ, Platko JV, Eva A, Henzel W, Evans T, Cerione RA. The identification and characterization of a GDP-dissociation inhibitor (GDI) for the CDC42Hs protein Journal of Biological Chemistry. 267: 22860-22868. PMID 1429634  1
1992 Guy PM, Carraway KL, Cerione RA. Biochemical comparisons of the normal and oncogenic forms of insect cell-expressed neu tyrosine kinases Journal of Biological Chemistry. 267: 13851-13856. PMID 1352772  1
1992 Narasimhan V, Hamill O, Cerione RA. The effects of the normal and oncogenic forms of the neu tyrosine kinase, and the corresponding forms of an immunoglobulin E receptor/neu tyrosine kinase fusion protein, on Xenopus oocyte maturation Febs Letters. 303: 164-168. PMID 1351469 DOI: 10.1016/0014-5793(92)80510-N  1
1991 Carraway KL, Cerione RA. Comparison of epidermal growth factor (EGF) receptor-receptor interactions in intact A431 cells and isolated plasma membranes: Large scale receptor micro-aggregation is not detected during EGF-stimulated early events Journal of Biological Chemistry. 266: 8899-8906. PMID 2026602  1
1991 Hart MJ, Eva A, Evans T, Aaronson SA, Cerione RA. Catalysis of guanine nucleotide exchange on the CDC42Hs protein by the dbl oncogene product Nature. 354: 311-314. PMID 1956381 DOI: 10.1038/354311A0  1
1991 Cerione RA. Reconstitution of receptor/GTP-binding protein interactions Bba - Reviews On Biomembranes. 1071: 473-501. PMID 1661159 DOI: 10.1016/0304-4157(91)90007-J  1
1991 Erickson JW, Cerione RA. Resonance Energy Transfer as a Direct Monitor of GTP-Binding Protein-Effector Interactions: Activated α-Transducin Binding to the cGMP Phosphodiesterase in the Bovine Phototransduction Cascade Biochemistry®. 30: 7112-7118. DOI: 10.1021/Bi00243A011  1
1990 Carraway KL, Koland JG, Cerione RA. Location of the epidermal growth factor binding site on the EGF receptor. A resonance energy transfer study Biochemistry. 29: 8741-8747. PMID 2271554 DOI: 10.1021/Bi00489A034  1
1988 Horne WA, Abdel-Ghany M, Racker E, Weiland GA, Oswald RE, Cerione RA. Functional reconstitution of skeletal muscle Ca2+ channels: separation of regulatory and channel components. Proceedings of the National Academy of Sciences of the United States of America. 85: 3718-22. PMID 2453879 DOI: 10.1073/Pnas.85.11.3718  1
1987 Cerione RA, Gierschik P, Staniszewski C, Benovic JL, Codina J, Somers R, Birnbaumer L, Spiegel AM, Lefkowitz RJ, Caron MG. Functional differences in the beta gamma complexes of transducin and the inhibitory guanine nucleotide regulatory protein. Biochemistry. 26: 1485-91. PMID 3032251 DOI: 10.1021/Bi00379A041  0.8
1987 Benovic JL, Staniszewski C, Cerione RA, Codina J, Lefkowitz RJ, Caron MG. The mammalian βadrenergic receptor: Structural and functional characterization of the carbohydrate moiety Journal of Receptors and Signal Transduction. 7: 257-281. PMID 2887651 DOI: 10.3109/10799898709054989  1
1986 Horne WA, Weiland GA, Oswald RE, Cerione RA. Rapid incorporation of the solubilized dihydropyridine receptor into phospholipid vesicles. Biochimica Et Biophysica Acta. 863: 205-12. PMID 3024719 DOI: 10.1016/0005-2736(86)90260-9  1
1985 Cerione RA, Codina J, Kilpatrick BF, Staniszewski C, Gierschik P, Somers RL, Spiegel AM, Birnbaumer L, Caron MG, Lefkowitz RJ. Transducin and the inhibitory nucleotide regulatory protein inhibit the stimulatory nucleotide regulatory protein mediated stimulation of adenylate cyclase in phospholipid vesicle systems. Biochemistry. 24: 4499-503. PMID 3933556 DOI: 10.1021/Bi00338A002  0.8
1985 Cerione RA, Staniszewski C, Caron MG, Lefkowitz RJ, Codina J, Birnbaumer L. A role for Ni in the hormonal stimulation of adenylate cyclase. Nature. 318: 293-5. PMID 2999605 DOI: 10.1038/318293a0  0.52
1985 Birnbaumer L, Codina J, Mattera R, Cerione RA, Hildebrandt JD, Sunyer T, Rojas FJ, Caron MG, Lefkowitz RJ, Iyengar R. Regulation of hormone receptors and adenylyl cyclases by guanine nucleotide binding N proteins. Recent Progress in Hormone Research. 41: 41-99. PMID 2996090 DOI: 10.1016/B978-0-12-571141-8.50006-8  0.8
1985 Lefkowitz RJ, Cerione RA, Codina J, Birnbaumer L, Caron MG. Reconstitution of the beta-adrenergic receptor. The Journal of Membrane Biology. 87: 1-12. PMID 2865370 DOI: 10.1007/BF01870694  0.44
1984 Cerione RA, Codina J, Benovic JL, Lefkowitz RJ, Birnbaumer L, Caron MG. The mammalian β2-adrenergic receptor: Reconstitution of functional interactions between pure receptor and pure stimulatory nucleotide binding protein of the adenylate cyclase system Biochemistry. 23: 4519-4525. PMID 6149763 DOI: 10.1021/Bi00315A003  1
1984 Strulovici B, Cerione RA, Kilpatrick BF, Caron MG, Lefkowitz RJ. Direct demonstration of impaired functionality of a purified desensitized beta-adrenergic receptor in a reconstituted system. Science (New York, N.Y.). 225: 837-40. PMID 6089331 DOI: 10.1126/Science.6089331  0.44
1983 Cerione RA, Strulovici B, Benovic JL, Lefkowitz RJ, Caron MG. Pure β-adrenergic receptor: the single polypeptide confers catecholamine responsiveness to adenylate cyclase Nature. 306: 562-566. PMID 6316161 DOI: 10.1038/306562A0  1
1983 Cerione RA, Strulovici B, Benovic JL, Strader CD, Caron MG, Lefkowitz RJ. Reconstitution of beta-adrenergic receptors in lipid vesicles: affinity chromatography-purified receptors confer catecholamine responsiveness on a heterologous adenylate cyclase system. Proceedings of the National Academy of Sciences of the United States of America. 80: 4899-903. PMID 6308659 DOI: 10.1073/Pnas.80.16.4899  0.52
1983 Cerione RA, McCarty RE, Hammes GG. Spatial relationships between specific sites on reconstituted chloroplast proton adenosinetriphosphatase and the phospholipid vesicle surface. Biochemistry. 22: 769-76. PMID 6220736 DOI: 10.1021/Bi00273A010  1
1982 Cerione RA, Hammes GG. Structural mapping of nucleotide binding sites on chloroplast coupling factor. Biochemistry. 21: 745-52. PMID 6462173 DOI: 10.1021/Bi00533A026  1
1981 Cerione RA, Hammes GG. Nucleotide interactions with the dicyclohexylcarbodiimide-sensitive adenosinetriphosphatase from spinach chloroplasts. Biochemistry. 20: 3359-65. PMID 6455155 DOI: 10.1021/Bi00515A008  1
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