Oscar Huang - Publications

Affiliations: 
Early Discovery Biochemistry Genentech Inc., Oceanside, CA, United States 

9 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Taylor AM, Côté A, Hewitt MC, Pastor R, Leblanc Y, Nasveschuk CG, Romero FA, Crawford TD, Cantone N, Jayaram H, Setser J, Murray J, Beresini MH, de Leon Boenig G, Chen Z, ... ... Huang OW, et al. Fragment-Based Discovery of a Selective and Cell-Active Benzodiazepinone CBP/EP300 Bromodomain Inhibitor (CPI-637). Acs Medicinal Chemistry Letters. 7: 531-536. PMID 27190605 DOI: 10.1021/acsmedchemlett.6b00075  0.6
2015 Flynn EM, Huang OW, Poy F, Oppikofer M, Bellon SF, Tang Y, Cochran AG. A Subset of Human Bromodomains Recognizes Butyryllysine and Crotonyllysine Histone Peptide Modifications. Structure (London, England : 1993). PMID 26365797 DOI: 10.1016/j.str.2015.08.004  0.6
2015 Taherbhoy AM, Huang OW, Cochran AG. BMI1-RING1B is an autoinhibited RING E3 ubiquitin ligase. Nature Communications. 6: 7621. PMID 26151332 DOI: 10.1038/ncomms8621  0.6
2015 Rutz S, Kayagaki N, Phung QT, Eidenschenk C, Noubade R, Wang X, Lesch J, Lu R, Newton K, Huang OW, Cochran AG, Vasser M, Fauber BP, DeVoss J, Webster J, et al. Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells. Nature. 518: 417-21. PMID 25470037 DOI: 10.1038/nature13979  0.6
2013 Huang OW, Cochran AG. Regulation of deubiquitinase proteolytic activity. Current Opinion in Structural Biology. 23: 806-11. PMID 23962487 DOI: 10.1016/j.sbi.2013.07.012  0.6
2012 Huang OW, Ma X, Yin J, Flinders J, Maurer T, Kayagaki N, Phung Q, Bosanac I, Arnott D, Dixit VM, Hymowitz SG, Starovasnik MA, Cochran AG. Phosphorylation-dependent activity of the deubiquitinase DUBA Nature Structural and Molecular Biology. 19: 171-176. PMID 22245969 DOI: 10.1038/nsmb.2206  0.6
2011 Bourhis E, Wang W, Tam C, Hwang J, Zhang Y, Spittler D, Huang OW, Gong Y, Estevez A, Zilberleyb I, Rouge L, Chiu C, Wu Y, Costa M, Hannoush RN, et al. Wnt antagonists bind through a short peptide to the first β-propeller domain of LRP5/6. Structure (London, England : 1993). 19: 1433-42. PMID 21944579 DOI: 10.1016/j.str.2011.07.005  0.6
2011 Dong KC, Helgason E, Yu C, Phu L, Arnott DP, Bosanac I, Compaan DM, Huang OW, Fedorova AV, Kirkpatrick DS, Hymowitz SG, Dueber EC. Preparation of distinct ubiquitin chain reagents of high purity and yield. Structure (London, England : 1993). 19: 1053-63. PMID 21827942 DOI: 10.1016/j.str.2011.06.010  0.6
2009 Aliagas-Martin I, Burdick D, Corson L, Dotson J, Drummond J, Fields C, Huang OW, Hunsaker T, Kleinheinz T, Krueger E, Liang J, Moffat J, Phillips G, Pulk R, Rawson TE, et al. A class of 2,4-bisanilinopyrimidine Aurora A inhibitors with unusually high selectivity against Aurora B. Journal of Medicinal Chemistry. 52: 3300-7. PMID 19402633 DOI: 10.1021/jm9000314  0.6
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