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Lawrence J. Stern, Ph.D. - Publications

Affiliations: 
1994-2002 Biological Chemistry Massachusetts Institute of Technology, Cambridge, MA, United States 
 2002- Biochemistry University of Massachusetts Medical Center, Worcester, MA, United States 
Area:
Pathology
Website:
http://web.mit.edu/stern/www

182 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Maben Z, Arya R, Georgiadis D, Stratikos E, Stern LJ. Conformational dynamics linked to domain closure and substrate binding explain the ERAP1 allosteric regulation mechanism. Nature Communications. 12: 5302. PMID 34489420 DOI: 10.1038/s41467-021-25564-w  1
2021 Clement CC, Nanaware PP, Stern LJ, Santambrogio L. A protocol for qualitative and quantitative measurement of endosomal processing using hot spot analysis. Star Protocols. 2: 100648. PMID 34278334 DOI: 10.1016/j.xpro.2021.100648  1
2021 Nanaware PP, Jurewicz MM, Clement CC, Lu L, Santambrogio L, Stern LJ. Distinguishing Signal From Noise in Immunopeptidome Studies of Limiting-Abundance Biological Samples: Peptides Presented by I-A in C57BL/6 Mouse Thymus. Frontiers in Immunology. 12: 658601. PMID 33995376 DOI: 10.3389/fimmu.2021.658601  1
2021 Clement CC, Nanaware PP, Yamazaki T, Negroni MP, Ramesh K, Morozova K, Thangaswamy S, Graves A, Kim HJ, Li TW, Vigano' M, Soni RK, Gadina M, Tse HY, Galluzzi L, ... ... Stern LJ, et al. Pleiotropic consequences of metabolic stress for the major histocompatibility complex class II molecule antigen processing and presentation machinery. Immunity. PMID 33725478 DOI: 10.1016/j.immuni.2021.02.019  1
2020 Mpakali A, Saridakis E, Giastas P, Maben Z, Stern LJ, Larhed M, Hallberg M, Stratikos E. Structural Basis of Inhibition of Insulin-Regulated Aminopeptidase by a Macrocyclic Peptidic Inhibitor. Acs Medicinal Chemistry Letters. 11: 1429-1434. PMID 32676150 DOI: 10.1021/Acsmedchemlett.0C00172  1
2020 Mavridis G, Arya R, Domnick A, Zoidakis J, Makridakis M, Vlahou A, Mpakali A, Lelis A, Georgiadis D, Tampé R, Papakyriakou A, Stern LJ, Stratikos E. A systematic re-examination of processing of MHCI-bound antigenic peptide precursors by ER aminopeptidase 1. The Journal of Biological Chemistry. PMID 32184355 DOI: 10.1074/Jbc.Ra120.012976  1
2020 Jiang W, Birtley JR, Hung SC, Wang W, Chiou SH, Macaubas C, Kornum B, Tian L, Huang H, Adler L, Weaver G, Lu L, Ilstad-Minnihan A, Somasundaram S, Ayyangar S, ... ... Stern LJ, et al. Author Correction: In vivo clonal expansion and phenotypes of hypocretin-specific CD4 T cells in narcolepsy patients and controls. Nature Communications. 11: 242. PMID 31913263 DOI: 10.1038/S41467-019-13776-0  1
2020 Kuo Y, King JD, Kuo C, Kenyon V, Park M, Chang W, Stern L, Brown CE, Williams JC. Abstract 6591: Antibody-based redirection of meditope-CAR T cells selectively kill antigen bearing tumor cells Immunology. DOI: 10.1158/1538-7445.Am2020-6591  0.04
2019 Nanaware PP, Jurewicz MM, Leszyk JD, Shaffer SA, Stern LJ. HLA-DO Modulates the Diversity of the MHC-II Self-peptidome. Molecular & Cellular Proteomics : McP. 18: 490-503. PMID 33431124 DOI: 10.1074/mcp.RA118.000956  1
2019 Maben Z, Arya R, Rane D, An WF, Metkar S, Hickey M, Bender S, Ali A, Nguyen TT, Evnouchidou I, Schilling RJ, Stratikos E, Golden JE, Stern LJ. Discovery of Selective Inhibitors of Endoplasmic Reticulum Aminopeptidase 1. Journal of Medicinal Chemistry. PMID 31841350 DOI: 10.1021/Acs.Jmedchem.9B00293  1
2019 Kamga L, Gil A, Song I, Brody R, Ghersi D, Aslan N, Stern LJ, Selin LK, Luzuriaga K. CDR3α drives selection of the immunodominant Epstein Barr virus (EBV) BRLF1-specific CD8 T cell receptor repertoire in primary infection. Plos Pathogens. 15: e1008122. PMID 31765434 DOI: 10.1371/Journal.Ppat.1008122  1
2019 Jiang W, Birtley JR, Hung SC, Wang W, Chiou SH, Macaubas C, Kornum B, Tian L, Huang H, Adler L, Weaver G, Lu L, Ilstad-Minnihan A, Somasundaram S, Ayyangar S, ... ... Stern LJ, et al. In vivo clonal expansion and phenotypes of hypocretin-specific CD4 T cells in narcolepsy patients and controls. Nature Communications. 10: 5247. PMID 31748512 DOI: 10.1038/S41467-019-13234-X  1
2019 Negroni MP, Cho OH, Stern LJ. Recognition of Listeria Infection by Germline Elements of the Vγ1.1 Vδ6.3 TCR. Immunohorizons. 3: 341-351. PMID 31356163 DOI: 10.4049/immunohorizons.1800040  1
2019 Joshi U, Pearson A, Evans JE, Langlois H, Saltiel N, Ojo J, Klimas N, Sullivan K, Keegan AP, Oberlin S, Darcey T, Cseresznye A, Raya B, Paris D, Hammock B, ... ... Stern LJ, et al. A permethrin metabolite is associated with adaptive immune responses in Gulf War Illness. Brain, Behavior, and Immunity. PMID 31325531 DOI: 10.1016/J.Bbi.2019.07.015  1
2019 Birtley JR, Alomary M, Zanini E, Antony J, Maben Z, Weaver GC, Von Arx C, Mura M, Marinho AT, Lu H, Morecroft EVN, Karali E, Chayen NE, Tate EW, Jurewicz M, ... Stern LJ, et al. Inactivating mutations and X-ray crystal structure of the tumor suppressor OPCML reveal cancer-associated functions. Nature Communications. 10: 3134. PMID 31316070 DOI: 10.1038/S41467-019-10966-8  0.01
2019 Koumantou D, Barnea E, Martin-Esteban A, Maben Z, Papakyriakou A, Mpakali A, Kokkala P, Pratsinis H, Georgiadis D, Stern LJ, Admon A, Stratikos E. Editing the immunopeptidome of melanoma cells using a potent inhibitor of endoplasmic reticulum aminopeptidase 1 (ERAP1). Cancer Immunology, Immunotherapy : Cii. PMID 31222486 DOI: 10.1007/S00262-019-02358-0  1
2019 Stadinski BD, Blevins SJ, Spidale NA, Duke BR, Huseby PG, Stern LJ, Huseby ES. A temporal thymic selection switch and ligand binding kinetics constrain neonatal Foxp3 T cell development. Nature Immunology. PMID 31209405 DOI: 10.1038/s41590-019-0414-1  1
2019 Jurewicz MM, Willis RA, Altman JD, Stern LJ. MHC-I peptide binding activity assessed by exchange after cleavage of peptide covalently linked to β2-microglobulin. Analytical Biochemistry. PMID 31201791 DOI: 10.1016/J.Ab.2019.05.017  0.01
2019 Becerra-Artiles A, Cruz J, Leszyk JD, Sidney J, Sette A, Shaffer SA, Stern LJ. Naturally processed HLA-DR3-restricted HHV-6b peptides are recognized broadly with polyfunctional and cytotoxic CD4 T cell responses. European Journal of Immunology. PMID 31020640 DOI: 10.1002/Eji.201948126  1
2019 Stadinski BD, Blevins SJ, Spidale NA, Duke BR, Huseby PG, Stern LJ, Huseby ES. A temporal thymic selection switch and ligand binding kinetics constrain neonatal Foxp3+Tregcell development. Nature Immunology. 20: 1046-1058. DOI: 10.2210/Pdb6Mno/Pdb  1
2019 Becerra‐Artiles A, Cruz J, Leszyk JD, Sidney J, Sette A, Shaffer SA, Stern LJ. Author response for "Naturally processed HLA‐DR3‐restricted HHV‐6b peptides are recognized broadly with polyfunctional and cytotoxic CD4 T cell responses" European Journal of Immunology. DOI: 10.1002/Eji.201948126/V2/Response1  1
2018 Nanaware PP, Jurewicz MM, Leszyk J, Shaffer SA, Stern LJ. HLA-DO modulates the diversity of the MHC-II self-peptidome. Molecular & Cellular Proteomics : McP. PMID 30573663 DOI: 10.1074/Mcp.Ra118.000956  1
2018 Jurewicz MM, Stern LJ. Class II MHC antigen processing in immune tolerance and inflammation. Immunogenetics. PMID 30421030 DOI: 10.1007/S00251-018-1095-X  0.01
2018 Jardetzky TS, Brown JH, Gorga JC, Stern LJ, Urban RG, Chi YI, Stauffacher C, Strominger JL, Wiley DC. Pillars Article: Three-Dimensional Structure of a Human Class II Histocompatibility Molecule Complexed with Superantigen. . 1994. 368: 711-718. Journal of Immunology (Baltimore, Md. : 1950). 201: 1819-1826. PMID 30224361  1
2018 Clement CC, Wang W, Dzieciatkowska M, Cortese M, Hansen KC, Becerra A, Thangaswamy S, Nizamutdinova I, Moon JY, Stern LJ, Gashev AA, Zawieja D, Santambrogio L. Quantitative Profiling of the Lymph Node Clearance Capacity. Scientific Reports. 8: 11253. PMID 30050160 DOI: 10.1038/S41598-018-29614-0  1
2018 Negroni MP, Stern LJ. The N-terminal region of photocleavable peptides that bind HLA-DR1 determines the kinetics of fragment release. Plos One. 13: e0199704. PMID 29965980 DOI: 10.1371/Journal.Pone.0199704  1
2018 Mpakali A, Maben Z, Stern LJ, Stratikos E. Molecular pathways for antigenic peptide generation by ER aminopeptidase 1. Molecular Immunology. PMID 29678301 DOI: 10.1016/J.Molimm.2018.03.026  1
2018 Becerra-Artiles A, Santoro T, Stern LJ. Evaluation of a method to measure HHV-6B infection in vitro based on cell size. Virology Journal. 15: 4. PMID 29304865 DOI: 10.1186/S12985-017-0917-Z  1
2017 Zimmermann K, Eells R, Heinrich F, Rintoul S, Josey B, Shekhar P, Lösche M, Stern LJ. The cytosolic domain of T-cell receptor ζ associates with membranes in a dynamic equilibrium and deeply penetrates the bilayer. The Journal of Biological Chemistry. PMID 28893902 DOI: 10.1074/Jbc.M117.794370  1
2017 Maldonado-Contreras A, Birtley JR, Boll E, Zhao Y, Mumy KL, Toscano J, Ayehunie S, Reinecker HC, Stern LJ, McCormick BA. Shigella Depends on SepA to Destabilize the Intestinal Epithelial Integrity via Cofilin Activation. Gut Microbes. 0. PMID 28598765 DOI: 10.1080/19490976.2017.1339006  0.01
2017 Song I, Gil A, Mishra R, Ghersi D, Selin LK, Stern LJ. Broad TCR repertoire and diverse structural solutions for recognition of an immunodominant CD8(+) T cell epitope. Nature Structural & Molecular Biology. PMID 28250417 DOI: 10.1038/Nsmb.3383  1
2017 Stamogiannos A, Maben Z, Papakyriakou A, Mpakali A, Kokkala P, Georgiadis D, Stern LJ, Stratikos E. Critical role of inter-domain interactions on the conformational change and catalytic mechanism of Endoplasmic Reticulum Aminopeptidase 1. Biochemistry. PMID 28218509 DOI: 10.1021/Acs.Biochem.6B01170  1
2016 Stern LJ, Santambrogio L. The melting pot of the MHC II peptidome. Current Opinion in Immunology. 40: 70-77. PMID 27018930 DOI: 10.1016/J.Coi.2016.03.004  1
2016 Clement CC, Moncriefe H, Lele A, Janow G, Becerra A, Bauli F, Saad FA, Perino G, Montagna C, Cobelli N, Hardin J, Stern LJ, Ilowite N, Porcelli SA, Santambrogio L. Autoimmune response to transthyretin in juvenile idiopathic arthritis. Jci Insight. 1. PMID 26973882 DOI: 10.1172/Jci.Insight.85633  1
2016 Hellman LM, Yin L, Wang Y, Blevins SJ, Riley TP, Belden OS, Spear TT, Nishimura MI, Stern LJ, Baker BM. Differential scanning fluorimetry based assessments of the thermal and kinetic stability of peptide-MHC complexes. Journal of Immunological Methods. PMID 26906089 DOI: 10.1016/J.Jim.2016.02.016  1
2016 Clement CC, Becerra A, Yin L, Zolla V, Huang L, Merlin S, Follenzi A, Shaffer SA, Stern LJ, Santambrogio L. The Dendritic Cell MHC II Peptidome Derives from a Variety of Processing Pathways and Includes Peptides with a Broad Spectrum of HLA-DM Sensitivity. The Journal of Biological Chemistry. PMID 26740625 DOI: 10.1074/Jbc.M115.655738  1
2015 Becerra-Artiles A, Dominguez-Amorocho O, Stern LJ, Calvo-Calle JM. A Simple Proteomics-Based Approach to Identification of Immunodominant Antigens from a Complex Pathogen: Application to the CD4 T Cell Response against Human Herpesvirus 6B. Plos One. 10: e0142871. PMID 26599878 DOI: 10.1371/Journal.Pone.0142871  1
2015 Yin L, Maben ZJ, Becerra A, Stern LJ. Evaluating the Role of HLA-DM in MHC Class II-Peptide Association Reactions. Journal of Immunology (Baltimore, Md. : 1950). PMID 26062997 DOI: 10.4049/Jimmunol.1403190  1
2015 Brown JH, Jardetzky TS, Gorga JC, Stern LJ, Urban RG, Strominger JL, Wiley DC. Pillars article: three-dimensional structure of the human class II histocompatibility antigen HLA-DR1. Nature. 1993. 364: 33-39. Journal of Immunology (Baltimore, Md. : 1950). 194: 5-11. PMID 25527791  1
2015 Brown JH, Jardetzky TS, Gorga JC, Stern LJ, Urban RG, Strominger JL, Wiley DC. Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1 Journal of Immunology. 194: 5-11.  1
2014 Becerra A, Gibson L, Stern LJ, Calvo-Calle JM. Immune response to HHV-6 and implications for immunotherapy. Current Opinion in Virology. 9: 154-61. PMID 25462448 DOI: 10.1016/J.Coviro.2014.10.001  1
2014 Yin L, Stern LJ. Measurement of Peptide Binding to MHC Class II Molecules by Fluorescence Polarization. Current Protocols in Immunology / Edited by John E. Coligan ... [Et Al.]. 106: 5.10.1-5.10.12. PMID 25081912 DOI: 10.1002/0471142735.Im0510S106  1
2014 Yin L, Trenh P, Guce A, Wieczorek M, Lange S, Sticht J, Jiang W, Bylsma M, Mellins ED, Freund C, Stern LJ. Susceptibility to HLA-DM protein is determined by a dynamic conformation of major histocompatibility complex class II molecule bound with peptide. The Journal of Biological Chemistry. 289: 23449-64. PMID 25002586 DOI: 10.1074/Jbc.M114.585539  1
2014 Parra-López CA, Bernal-Estévez D, Yin L, Vargas LE, Pulido-Calixto C, Salazar LM, Calvo-Calle JM, Stern LJ. An unstable Th epitope of P. falciparum fosters central memory T cells and anti-CS antibody responses. Plos One. 9: e100639. PMID 24983460 DOI: 10.1371/Journal.Pone.0100639  1
2014 Stadinski BD, Trenh P, Duke B, Huseby PG, Li G, Stern LJ, Huseby ES. Effect of CDR3 sequences and distal V gene residues in regulating TCR-MHC contacts and ligand specificity. Journal of Immunology (Baltimore, Md. : 1950). 192: 6071-82. PMID 24813203 DOI: 10.4049/Jimmunol.1303209  1
2014 Parra M, Herrera D, Calvo-Calle JM, Stern LJ, Parra-López CA, Butcher E, Franco M, Angel J. Circulating human rotavirus specific CD4 T cells identified with a class II tetramer express the intestinal homing receptors α4β7 and CCR9. Virology. 452: 191-201. PMID 24606696 DOI: 10.1016/J.Virol.2014.01.014  1
2014 Yin L, Stern LJ. A novel method to measure HLA-DM-susceptibility of peptides bound to MHC class II molecules based on peptide binding competition assay and differential IC(50) determination. Journal of Immunological Methods. 406: 21-33. PMID 24583195 DOI: 10.1016/J.Jim.2014.02.008  1
2014 Mellins ED, Stern LJ. HLA-DM and HLA-DO, key regulators of MHC-II processing and presentation. Current Opinion in Immunology. 26: 115-22. PMID 24463216 DOI: 10.1016/J.Coi.2013.11.005  1
2014 Mauricio Calvo-Calle J, Stern LJ. The Immune Response to HHV-6 Human Herpesviruses Hhv-6a, Hhv-6b, and Hhv-7, Third Edition. 235-249. DOI: 10.1016/B978-0-444-62703-2.00014-8  1
2013 Yin L, Stern LJ. HLA-DM Focuses on Conformational Flexibility Around P1 Pocket to Catalyze Peptide Exchange. Frontiers in Immunology. 4: 336. PMID 24146666 DOI: 10.3389/Fimmu.2013.00336  1
2013 Shen ZT, Nguyen TT, Daniels KA, Welsh RM, Stern LJ. Disparate epitopes mediating protective heterologous immunity to unrelated viruses share peptide-MHC structural features recognized by cross-reactive T cells. Journal of Immunology (Baltimore, Md. : 1950). 191: 5139-52. PMID 24127554 DOI: 10.4049/Jimmunol.1300852  1
2013 Santambrogio L, Stern LJ. Carrying yourself: self antigen composition of the lymphatic fluid. Lymphatic Research and Biology. 11: 149-54. PMID 24024574 DOI: 10.1089/Lrb.2013.0009  1
2013 Serra-Moreno R, Zimmermann K, Stern LJ, Evans DT. Tetherin/BST-2 antagonism by Nef depends on a direct physical interaction between Nef and tetherin, and on clathrin-mediated endocytosis. Plos Pathogens. 9: e1003487. PMID 23853598 DOI: 10.1371/Journal.Ppat.1003487  1
2013 Yin L, Calvo-Calle JM, Cruz J, Newman FK, Frey SE, Ennis FA, Stern LJ. CD4+ T cells provide intermolecular help to generate robust antibody responses in vaccinia virus-vaccinated humans. Journal of Immunology (Baltimore, Md. : 1950). 190: 6023-33. PMID 23667112 DOI: 10.4049/Jimmunol.1202523  1
2013 Stratikos E, Stern LJ. Antigenic peptide trimming by ER aminopeptidases--insights from structural studies. Molecular Immunology. 55: 212-9. PMID 23545452 DOI: 10.1016/J.Molimm.2013.03.002  1
2013 Guce AI, Mortimer SE, Yoon T, Painter CA, Jiang W, Mellins ED, Stern LJ. HLA-DO acts as a substrate mimic to inhibit HLA-DM by a competitive mechanism. Nature Structural & Molecular Biology. 20: 90-8. PMID 23222639 DOI: 10.1038/Nsmb.2460  1
2012 Painter CA, Stern LJ. Conformational variation in structures of classical and non-classical MHCII proteins and functional implications. Immunological Reviews. 250: 144-57. PMID 23046127 DOI: 10.1111/Imr.12003  1
2012 Farfán-Arribas DJ, Stern LJ, Rock KL. Using intein catalysis to probe the origin of major histocompatibility complex class I-presented peptides. Proceedings of the National Academy of Sciences of the United States of America. 109: 16998-7003. PMID 23027972 DOI: 10.1073/Pnas.1210271109  1
2012 Yin L, Calvo-Calle JM, Dominguez-Amorocho O, Stern LJ. HLA-DM constrains epitope selection in the human CD4 T cell response to vaccinia virus by favoring the presentation of peptides with longer HLA-DM-mediated half-lives. Journal of Immunology (Baltimore, Md. : 1950). 189: 3983-94. PMID 22966084 DOI: 10.4049/Jimmunol.1200626  1
2012 Holland CJ, Rizkallah PJ, Vollers S, Calvo-Calle JM, Madura F, Fuller A, Sewell AK, Stern LJ, Godkin A, Cole DK. Minimal conformational plasticity enables TCR cross-reactivity to different MHC class II heterodimers. Scientific Reports. 2: 629. PMID 22953050 DOI: 10.1038/Srep00629  1
2012 Yoon T, Macmillan H, Mortimer SE, Jiang W, Rinderknecht CH, Stern LJ, Mellins ED. Mapping the HLA-DO/HLA-DM complex by FRET and mutagenesis. Proceedings of the National Academy of Sciences of the United States of America. 109: 11276-81. PMID 22733780 DOI: 10.1073/Pnas.1113966109  1
2012 Huseby ES, Stadinski BD, Trenh P, Stern LJ. Response to Garcia et al. Immunity. 36: 889-90. PMID 22705102 DOI: 10.1016/J.Immuni.2012.05.019  1
2012 Nastke MD, Becerra A, Yin L, Dominguez-Amorocho O, Gibson L, Stern LJ, Calvo-Calle JM. Human CD4+ T cell response to human herpesvirus 6. Journal of Virology. 86: 4776-92. PMID 22357271 DOI: 10.1128/Jvi.06573-11  1
2012 Rice JM, Stern LJ, Guignon EF, Lawrence DA, Lynes MA. Antigen-specific T cell phenotyping microarrays using grating coupled surface plasmon resonance imaging and surface plasmon coupled emission. Biosensors & Bioelectronics. 31: 264-9. PMID 22104646 DOI: 10.1016/J.Bios.2011.10.029  1
2012 Huseby ES, Stadinski BD, Trenh P, Stern LJ. Response to Garcia et al. Immunity. 36: 889-890. DOI: 10.1016/j.immuni.2012.05.019  1
2011 Painter CA, Stern LJ. Structural Insights Into HLA-DM Mediated MHC II Peptide Exchange. Current Topics in Biochemical Research. 13: 39-55. PMID 25264402  1
2011 Stadinski BD, Trenh P, Smith RL, Bautista B, Huseby PG, Li G, Stern LJ, Huseby ES. A role for differential variable gene pairing in creating T cell receptors specific for unique major histocompatibility ligands. Immunity. 35: 694-704. PMID 22101158 DOI: 10.1016/J.Immuni.2011.10.012  1
2011 Painter CA, Negroni MP, Kellersberger KA, Zavala-Ruiz Z, Evans JE, Stern LJ. Conformational lability in the class II MHC 310 helix and adjacent extended strand dictate HLA-DM susceptibility and peptide exchange. Proceedings of the National Academy of Sciences of the United States of America. 108: 19329-34. PMID 22084083 DOI: 10.1073/Pnas.1108074108  1
2011 Nguyen TT, Chang SC, Evnouchidou I, York IA, Zikos C, Rock KL, Goldberg AL, Stratikos E, Stern LJ. Structural basis for antigenic peptide precursor processing by the endoplasmic reticulum aminopeptidase ERAP1. Nature Structural & Molecular Biology. 18: 604-13. PMID 21478864 DOI: 10.1038/Nsmb.2021  1
2010 Shen ZT, Brehm MA, Daniels KA, Sigalov AB, Selin LK, Welsh RM, Stern LJ. Bi-specific MHC heterodimers for characterization of cross-reactive T cells. The Journal of Biological Chemistry. 285: 33144-53. PMID 20729210 DOI: 10.1074/Jbc.M110.141051  1
2010 Ge X, Gebe JA, Bollyky PL, James EA, Yang J, Stern LJ, Kwok WW. Peptide-MHC cellular microarray with innovative data analysis system for simultaneously detecting multiple CD4 T-cell responses. Plos One. 5: e11355. PMID 20634998 DOI: 10.1371/Journal.Pone.0011355  1
2010 Clement CC, Cannizzo ES, Nastke MD, Sahu R, Olszewski W, Miller NE, Stern LJ, Santambrogio L. An expanded self-antigen peptidome is carried by the human lymph as compared to the plasma. Plos One. 5: e9863. PMID 20360855 DOI: 10.1371/Journal.Pone.0009863  1
2010 Moutaftsi M, Tscharke DC, Vaughan K, Koelle DM, Stern L, Calvo-Calle M, Ennis F, Terajima M, Sutter G, Crotty S, Drexler I, Franchini G, Yewdell JW, Head SR, Blum J, et al. Uncovering the interplay between CD8, CD4 and antibody responses to complex pathogens. Future Microbiology. 5: 221-39. PMID 20143946 DOI: 10.2217/Fmb.09.110  1
2010 Kim WM, Sigalov AB, Stern LJ. Pseudo-merohedral twinning and noncrystallographic symmetry in orthorhombic crystals of SIVmac239 Nef core domain bound to different-length TCRzeta fragments. Acta Crystallographica. Section D, Biological Crystallography. 66: 163-75. PMID 20124696 DOI: 10.1107/S090744490904880X  1
2010 Perkins RB, Langrish SM, Stern LJ, Burgess JF, Simon CJ. Impact of patient adherence and test performance on the cost-effectiveness of cervical cancer screening in developing countries: the case of Honduras. Women's Health Issues : Official Publication of the Jacobs Institute of Women's Health. 20: 35-42. PMID 19944623 DOI: 10.1016/j.whi.2009.09.001  1
2009 Stern LJ, Calvo-Calle JM. HLA-DR: molecular insights and vaccine design. Current Pharmaceutical Design. 15: 3249-61. PMID 19860674 DOI: 10.2174/138161209789105171  1
2009 Campbell JD, Buckland KF, McMillan SJ, Kearley J, Oldfield WL, Stern LJ, Grönlund H, van Hage M, Reynolds CJ, Boyton RJ, Cobbold SP, Kay AB, Altmann DM, Lloyd CM, Larché M. Peptide immunotherapy in allergic asthma generates IL-10-dependent immunological tolerance associated with linked epitope suppression. The Journal of Experimental Medicine. 206: 1535-47. PMID 19528258 DOI: 10.1084/Jem.20082901  1
2009 Strug I, Calvo-Calle JM, Green KM, Cruz J, Ennis FA, Evans JE, Stern LJ. Vaccinia peptides eluted from HLA-DR1 isolated From virus-infected cells are recognized by CD4+ T cells from a vaccinated donor (Journal of Proteome Research (2008) 7 (2703-2711)) Journal of Proteome Research. 8: 1104. DOI: 10.1021/pr801121f  1
2008 Sigalov AB, Kim WM, Saline M, Stern LJ. The intrinsically disordered cytoplasmic domain of the T cell receptor zeta chain binds to the nef protein of simian immunodeficiency virus without a disorder-to-order transition. Biochemistry. 47: 12942-4. PMID 19012413 DOI: 10.1021/Bi801602P  1
2008 Painter CA, Cruz A, López GE, Stern LJ, Zavala-Ruiz Z. Model for the peptide-free conformation of class II MHC proteins. Plos One. 3: e2403. PMID 18545669 DOI: 10.1371/Journal.Pone.0002403  1
2008 Strug I, Calvo-Calle JM, Green KM, Cruz J, Ennis FA, Evans JE, Stern LJ. Vaccinia peptides eluted from HLA-DR1 isolated from virus-infected cells are recognized by CD4+ T cells from a vaccinated donor. Journal of Proteome Research. 7: 2703-11. PMID 18507432 DOI: 10.1021/Pr700780X  1
2008 Vollers SS, Stern LJ. Class II major histocompatibility complex tetramer staining: progress, problems, and prospects. Immunology. 123: 305-13. PMID 18251991 DOI: 10.1111/J.1365-2567.2007.02801.X  1
2008 Chitta S, Santambrogio L, Stern LJ. GMCSF in the absence of other cytokines sustains human dendritic cell precursors with T cell regulatory activity and capacity to differentiate into functional dendritic cells. Immunology Letters. 116: 41-54. PMID 18166231 DOI: 10.1016/J.Imlet.2007.11.013  1
2007 Perkins RB, Langrish S, Stern LJ, Simon CJ. A community-based education program about cervical cancer improves knowledge and screening behavior in Honduran women. Revista Panamericana De Salud PúBlica = Pan American Journal of Public Health. 22: 187-93. PMID 18062853  1
2007 Calvo-Calle JM, Strug I, Nastke MD, Baker SP, Stern LJ. Human CD4+ T cell epitopes from vaccinia virus induced by vaccination or infection. Plos Pathogens. 3: 1511-29. PMID 17937498 DOI: 10.1371/Journal.Ppat.0030144  1
2007 Perkins RB, Langrish SM, Stern LJ, Figueroa J, Simon CJ. Comparison of visual inspection and Papanicolau (PAP) smears for cervical cancer screening in Honduras: should PAP smears be abandoned? Tropical Medicine & International Health : Tm & Ih. 12: 1018-25. PMID 17875013 DOI: 10.1111/j.1365-3156.2007.01888.x  1
2007 Stern LJ. Characterizing MHC-associated peptides by mass spectrometry. Journal of Immunology (Baltimore, Md. : 1950). 179: 2667-8. PMID 17709475 DOI: 10.4049/Jimmunol.179.5.2667  1
2007 Mitra-Kaushik S, Cruz J, Stern LJ, Ennis FA, Terajima M. Human cytotoxic CD4+ T cells recognize HLA-DR1-restricted epitopes on vaccinia virus proteins A24R and D1R conserved among poxviruses. Journal of Immunology (Baltimore, Md. : 1950). 179: 1303-12. PMID 17617623 DOI: 10.4049/Jimmunol.179.2.1303  1
2007 Parry CS, Gorski J, Stern LJ. Crystallographic structure of the human leukocyte antigen DRA, DRB3*0101: models of a directional alloimmune response and autoimmunity. Journal of Molecular Biology. 371: 435-46. PMID 17583734 DOI: 10.1016/J.Jmb.2007.05.025  1
2007 Duchardt E, Sigalov AB, Aivazian D, Stern LJ, Schwalbe H. Structure induction of the T-cell receptor zeta-chain upon lipid binding investigated by NMR spectroscopy. Chembiochem : a European Journal of Chemical Biology. 8: 820-7. PMID 17410622 DOI: 10.1002/Cbic.200600413  1
2007 Venkatraman P, Nguyen TT, Sainlos M, Bilsel O, Chitta S, Imperiali B, Stern LJ. Fluorogenic probes for monitoring peptide binding to class II MHC proteins in living cells. Nature Chemical Biology. 3: 222-8. PMID 17351628 DOI: 10.1038/Nchembio868  1
2007 Younes SA, Trautmann L, Yassine-Diab B, Kalfayan LH, Kernaleguen AE, Cameron TO, Boulassel R, Stern LJ, Routy JP, Grossman Z, Dumont AR, Sekaly RP. The duration of exposure to HIV modulates the breadth and the magnitude of HIV-specific memory CD4+ T cells. Journal of Immunology (Baltimore, Md. : 1950). 178: 788-97. PMID 17202340 DOI: 10.4049/Jimmunol.178.2.788  1
2006 Sigalov AB, Aivazian DA, Uversky VN, Stern LJ. Lipid-binding activity of intrinsically unstructured cytoplasmic domains of multichain immune recognition receptor signaling subunits. Biochemistry. 45: 15731-9. PMID 17176095 DOI: 10.1021/Bi061108F  1
2006 Parra-López C, Calvo-Calle JM, Cameron TO, Vargas LE, Salazar LM, Patarroyo ME, Nardin E, Stern LJ. Major histocompatibility complex and T cell interactions of a universal T cell epitope from Plasmodium falciparum circumsporozoite protein. The Journal of Biological Chemistry. 281: 14907-17. PMID 16565072 DOI: 10.1074/Jbc.M511571200  1
2006 De Wall SL, Painter C, Stone JD, Bandaranayake R, Wiley DC, Mitchison TJ, Stern LJ, DeDecker BS. Noble metals strip peptides from class II MHC proteins. Nature Chemical Biology. 2: 197-201. PMID 16505807 DOI: 10.1038/Nchembio773  1
2006 Stone JD, Stern LJ. CD8 T cells, like CD4 T cells, are triggered by multivalent engagement of TCRs by MHC-peptide ligands but not by monovalent engagement. Journal of Immunology (Baltimore, Md. : 1950). 176: 1498-505. PMID 16424178 DOI: 10.4049/Jimmunol.176.3.1498  1
2006 Stern LJ, Potolicchio I, Santambrogio L. MHC class II compartment subtypes: structure and function. Current Opinion in Immunology. 18: 64-9. PMID 16337363 DOI: 10.1016/J.Coi.2005.11.005  1
2006 Norris PJ, Stone JD, Anikeeva N, Heitman JW, Wilson IC, Hirschkorn DF, Clark MJ, Moffett HF, Cameron TO, Sykulev Y, Stern LJ, Walker BD. Antagonism of HIV-specific CD4+ T cells by C-terminal truncation of a minimum epitope. Molecular Immunology. 43: 1349-57. PMID 16216327 DOI: 10.1016/J.Molimm.2005.09.004  1
2005 Carven GJ, Stern LJ. Probing the ligand-induced conformational change in HLA-DR1 by selective chemical modification and mass spectrometric mapping. Biochemistry. 44: 13625-37. PMID 16229453 DOI: 10.1021/Bi050972P  1
2005 Potolicchio I, Chitta S, Xu X, Fonseca D, Crisi G, Horejsi V, Strominger JL, Stern LJ, Raposo G, Santambrogio L. Conformational variation of surface class II MHC proteins during myeloid dendritic cell differentiation accompanies structural changes in lysosomal MIIC. Journal of Immunology (Baltimore, Md. : 1950). 175: 4935-47. PMID 16210595 DOI: 10.4049/Jimmunol.175.8.4935  1
2005 Potolicchio I, Carven GJ, Xu X, Stipp C, Riese RJ, Stern LJ, Santambrogio L. Proteomic analysis of microglia-derived exosomes: metabolic role of the aminopeptidase CD13 in neuropeptide catabolism. Journal of Immunology (Baltimore, Md. : 1950). 175: 2237-43. PMID 16081791 DOI: 10.4049/Jimmunol.175.4.2237  1
2005 Stone JD, Demkowicz WE, Stern LJ. HLA-restricted epitope identification and detection of functional T cell responses by using MHC-peptide and costimulatory microarrays. Proceedings of the National Academy of Sciences of the United States of America. 102: 3744-9. PMID 15728728 DOI: 10.1073/Pnas.0407019102  1
2005 Baggio R, Carven GJ, Chiulli A, Palmer M, Stern LJ, Arenas JE. Induced fit of an epitope peptide to a monoclonal antibody probed with a novel parallel surface plasmon resonance assay. The Journal of Biological Chemistry. 280: 4188-94. PMID 15556932 DOI: 10.1074/Jbc.M410687200  1
2005 Murakami M, Dorschner RA, Stern LJ, Lin KH, Gallo RL. Expression and secretion of cathelicidin antimicrobial peptides in murine mammary glands and human milk. Pediatric Research. 57: 10-5. PMID 15531744 DOI: 10.1203/01.Pdr.0000148068.32201.50  1
2004 Zavala-Ruiz Z, Strug I, Anderson MW, Gorski J, Stern LJ. A polymorphic pocket at the P10 position contributes to peptide binding specificity in class II MHC proteins. Chemistry & Biology. 11: 1395-402. PMID 15489166 DOI: 10.1016/J.Chembiol.2004.08.007  1
2004 Oken E, Martinez Stoffel E, Stern LJ. Use of volunteer medical brigades to assess growth in Honduras. Journal of Tropical Pediatrics. 50: 203-8. PMID 15357558 DOI: 10.1093/tropej/50.4.203  1
2004 Zavala-Ruiz Z, Strug I, Walker BD, Norris PJ, Stern LJ. A hairpin turn in a class II MHC-bound peptide orients residues outside the binding groove for T cell recognition. Proceedings of the National Academy of Sciences of the United States of America. 101: 13279-84. PMID 15331779 DOI: 10.1073/Pnas.0403371101  1
2004 Sigalov A, Aivazian D, Stern L. Homooligomerization of the Cytoplasmic Domain of the T Cell Receptor ζ Chain and of Other Proteins Containing the Immunoreceptor Tyrosine-Based Activation Motif Biochemistry. 43: 2049-2061. PMID 14967045 DOI: 10.1021/Bi035900H  1
2004 Carven GJ, Chitta S, Hilgert I, Rushe MM, Baggio RF, Palmer M, Arenas JE, Strominger JL, Horejsi V, Santambrogio L, Stern LJ. Monoclonal antibodies specific for the empty conformation of HLA-DR1 reveal aspects of the conformational change associated with peptide binding. The Journal of Biological Chemistry. 279: 16561-70. PMID 14757758 DOI: 10.1074/Jbc.M314315200  1
2004 Stratikos E, Wiley DC, Stern LJ. Enhanced catalytic action of HLA-DM on the exchange of peptides lacking backbone hydrogen bonds between their N-terminal region and the MHC class II alpha-chain. Journal of Immunology (Baltimore, Md. : 1950). 172: 1109-17. PMID 14707085 DOI: 10.4049/Jimmunol.172.2.1109  1
2003 Zavala-Ruiz Z, Sundberg EJ, Stone JD, DeOliveira DB, Chan IC, Svendsen J, Mariuzza RA, Stern LJ. Exploration of the P6/P7 region of the peptide-binding site of the human class II major histocompatability complex protein HLA-DR1. The Journal of Biological Chemistry. 278: 44904-12. PMID 12952957 DOI: 10.1074/Jbc.M307652200  1
2002 Cameron TO, Cohen GB, Islam SA, Stern LJ. Examination of the highly diverse CD4(+) T-cell repertoire directed against an influenza peptide: a step towards TCR proteomics. Immunogenetics. 54: 611-20. PMID 12466894 DOI: 10.1007/S00251-002-0508-Y  1
2002 Ge Q, Stone JD, Thompson MT, Cochran JR, Rushe M, Eisen HN, Chen J, Stern LJ. Soluble peptide-MHC monomers cause activation of CD8+ T cells through transfer of the peptide to T cell MHC molecules. Proceedings of the National Academy of Sciences of the United States of America. 99: 13729-34. PMID 12374859 DOI: 10.1073/Pnas.212515299  1
2002 Sigalov AB, Stern LJ. Dihydrolipoic acid as an effective cofactor for peptide methionine sulfoxide reductase in enzymatic repair of oxidative damage to both lipid-free and lipid-bound apolipoprotein a-I. Antioxidants & Redox Signaling. 4: 553-7. PMID 12215223 DOI: 10.1089/15230860260196353  1
2002 Cameron TO, Norris PJ, Patel A, Moulon C, Rosenberg ES, Mellins ED, Wedderburn LR, Stern LJ. Labeling antigen-specific CD4(+) T cells with class II MHC oligomers. Journal of Immunological Methods. 268: 51-69. PMID 12213343 DOI: 10.1016/S0022-1759(02)00200-4  1
2002 Re F, Belyanskaya SL, Riese RJ, Cipriani B, Fischer FR, Granucci F, Ricciardi-Castagnoli P, Brosnan C, Stern LJ, Strominger JL, Santambrogio L. Granulocyte-macrophage colony-stimulating factor induces an expression program in neonatal microglia that primes them for antigen presentation. Journal of Immunology (Baltimore, Md. : 1950). 169: 2264-73. PMID 12193691 DOI: 10.4049/Jimmunol.169.5.2264  1
2002 Zaru R, Cameron TO, Stern LJ, Müller S, Valitutti S. Cutting edge: TCR engagement and triggering in the absence of large-scale molecular segregation at the T cell-APC contact site. Journal of Immunology (Baltimore, Md. : 1950). 168: 4287-91. PMID 11970969 DOI: 10.4049/Jimmunol.168.9.4287  1
2001 Asherie N, Pande J, Pande A, Zarutskie JA, Lomakin J, Lomakin A, Ogun O, Stern LJ, King J, Benedek GB. Enhanced crystallization of the Cys18 to Ser mutant of bovine gammaB crystallin. Journal of Molecular Biology. 314: 663-9. PMID 11733987 DOI: 10.1006/Jmbi.2001.5155  1
2001 Sigalov AB, Stern LJ. Oxidation of methionine residues affects the structure and stability of apolipoprotein A-I in reconstituted high density lipoprotein particles. Chemistry and Physics of Lipids. 113: 133-46. PMID 11687233 DOI: 10.1016/S0009-3084(01)00186-4  1
2001 Zarutskie JA, Busch R, Zavala-Ruiz Z, Rushe M, Mellins ED, Stern LJ. The kinetic basis of peptide exchange catalysis by HLA-DM. Proceedings of the National Academy of Sciences of the United States of America. 98: 12450-5. PMID 11606721 DOI: 10.1073/Pnas.211439398  1
2001 Stone JD, Cochran JR, Stern LJ. T-cell activation by soluble MHC oligomers can be described by a two-parameter binding model. Biophysical Journal. 81: 2547-57. PMID 11606269 DOI: 10.1016/S0006-3495(01)75899-7  1
2001 Cameron TO, Stone JD, Cochran JR, Stern LJ. TCR: losing its inhibitions? Trends in Immunology. 22: 479-80. PMID 11556322 DOI: 10.1016/S1471-4906(01)01996-2  1
2001 Cochran JR, Cameron TO, Stone JD, Lubetsky JB, Stern LJ. Receptor proximity, not intermolecular orientation, is critical for triggering T-cell activation. The Journal of Biological Chemistry. 276: 28068-74. PMID 11384988 DOI: 10.1074/Jbc.M103280200  1
2001 Santambrogio L, Belyanskaya SL, Fischer FR, Cipriani B, Brosnan CF, Ricciardi-Castagnoli P, Stern LJ, Strominger JL, Riese R. Developmental plasticity of CNS microglia. Proceedings of the National Academy of Sciences of the United States of America. 98: 6295-300. PMID 11371643 DOI: 10.1073/Pnas.111152498  1
2001 Cochran JR, Aivazian D, Cameron TO, Stern LJ. Receptor clustering and transmembrane signaling in T cells. Trends in Biochemical Sciences. 26: 304-10. PMID 11343923 DOI: 10.1016/S0968-0004(01)01815-1  1
2001 Cameron TO, Cochran JR, Yassine-Diab B, Sékaly RP, Stern LJ. Cutting edge: detection of antigen-specific CD4+ T cells by HLA-DR1 oligomers is dependent on the T cell activation state. Journal of Immunology (Baltimore, Md. : 1950). 166: 741-5. PMID 11145645 DOI: 10.4049/Jimmunol.166.2.741  1
2000 De Oliveira DB, Harfouch-Hammoud E, Otto H, Papandreou NA, Stern LJ, Cohen H, Boehm BO, Bach J, Caillat-Zucman S, Walk T, Jung G, Eliopoulos E, Papadopoulos GK, van Endert PM. Structural analysis of two HLA-DR-presented autoantigenic epitopes: crucial role of peripheral but not central peptide residues for T-cell receptor recognition. Molecular Immunology. 37: 813-25. PMID 11257303 DOI: 10.1016/S0161-5890(00)00109-7  1
2000 Aivazian D, Stern LJ. Phosphorylation of T cell receptor zeta is regulated by a lipid dependent folding transition. Nature Structural Biology. 7: 1023-6. PMID 11062556 DOI: 10.1038/80930  1
2000 Cochran JR, Stern LJ. A diverse set of oligomeric class II MHC-peptide complexes for probing T-cell receptor interactions. Chemistry & Biology. 7: 683-96. PMID 10980449 DOI: 10.1016/S1074-5521(00)00019-3  1
2000 Cochran JR, Cameron TO, Stern LJ. The relationship of MHC-peptide binding and T cell activation probed using chemically defined MHC class II oligomers. Immunity. 12: 241-50. PMID 10755611 DOI: 10.1016/S1074-7613(00)80177-6  1
2000 Joshi RV, Zarutskie JA, Stern LJ. A three-step kinetic mechanism for peptide binding to MHC class II proteins. Biochemistry. 39: 3751-62. PMID 10736175 DOI: 10.1021/Bi9923656  1
2000 Sato AK, Zarutskie JA, Rushe MM, Lomakin A, Natarajan SK, Sadegh-Nasseri S, Benedek GB, Stern LJ. Determinants of the peptide-induced conformational change in the human class II major histocompatibility complex protein HLA-DR1. The Journal of Biological Chemistry. 275: 2165-73. PMID 10636922 DOI: 10.1074/Jbc.275.3.2165  1
1999 Sato AK, Sturniolo T, Sinigaglia F, Stern LJ. Substitution of aspartic acid at beta57 with alanine alters MHC class II peptide binding activity but not protein stability: HLA-DQ (alpha1*0201, beta1*0302) and (alpha1*0201, beta1*0303). Human Immunology. 60: 1227-36. PMID 10626736 DOI: 10.1016/S0198-8859(99)00120-2  1
1999 Santambrogio L, Sato AK, Carven GJ, Belyanskaya SL, Strominger JL, Stern LJ. Extracellular antigen processing and presentation by immature dendritic cells. Proceedings of the National Academy of Sciences of the United States of America. 96: 15056-61. PMID 10611337 DOI: 10.1073/Pnas.96.26.15056  1
1999 Santambrogio L, Sato AK, Fischer FR, Dorf ME, Stern LJ. Abundant empty class II MHC molecules on the surface of immature dendritic cells. Proceedings of the National Academy of Sciences of the United States of America. 96: 15050-5. PMID 10611336 DOI: 10.1073/Pnas.96.26.15050  1
1999 Zarutskie JA, Sato AK, Rushe MM, Chan IC, Lomakin A, Benedek GB, Stern LJ. A conformational change in the human major histocompatibility complex protein HLA-DR1 induced by peptide binding. Biochemistry. 38: 5878-87. PMID 10231540 DOI: 10.1021/Bi983048M  1
1999 Natarajan SK, Stern LJ, Sadegh-Nasseri S. Sodium dodecyl sulfate stability of HLA-DR1 complexes correlates with burial of hydrophobic residues in pocket 1. Journal of Immunology (Baltimore, Md. : 1950). 162: 3463-70. PMID 10092802  1
1999 Frayser M, Sato AK, Xu L, Stern LJ. Empty and peptide-loaded class II major histocompatibility complex proteins produced by expression in Escherichia coli and folding in vitro. Protein Expression and Purification. 15: 105-14. PMID 10024477 DOI: 10.1006/Prep.1998.0987  1
1998 Schmitke JL, Stern LJ, Klibanov AM. Comparison of x-ray crystal structures of an acyl-enzyme intermediate of subtilisin Carlsberg formed in anhydrous acetonitrile and in water. Proceedings of the National Academy of Sciences of the United States of America. 95: 12918-23. PMID 9789015 DOI: 10.1073/Pnas.95.22.12918  1
1998 Sigalov AB, Stern LJ. Enzymatic repair of oxidative damage to human apolipoprotein A-I. Febs Letters. 433: 196-200. PMID 9744793 DOI: 10.1016/S0014-5793(98)00908-9  1
1998 Schmitke JL, Stern LJ, Klibanov AM. Organic solvent binding to crystalline subtilisin1 in mostly aqueous media and in the neat solvents. Biochemical and Biophysical Research Communications. 248: 273-7. PMID 9675126 DOI: 10.1006/Bbrc.1998.8937  1
1997 Murthy VL, Stern LJ. The class II MHC protein HLA-DR1 in complex with an endogenous peptide: implications for the structural basis of the specificity of peptide binding. Structure (London, England : 1993). 5: 1385-96. PMID 9351812 DOI: 10.1016/S0969-2126(97)00288-8  1
1997 Schmitke JL, Stern LJ, Klibanov AM. The crystal structure of subtilisin Carlsberg in anhydrous dioxane and its comparison with those in water and acetonitrile. Proceedings of the National Academy of Sciences of the United States of America. 94: 4250-5. PMID 9113975 DOI: 10.1073/Pnas.94.9.4250  1
1996 Jardetzky TS, Brown JH, Gorga JC, Stern LJ, Urban RG, Strominger JL, Wiley DC. Crystallographic analysis of endogenous peptides associated with HLA-DR1 suggests a common, polyproline II-like conformation for bound peptides. Proceedings of the National Academy of Sciences of the United States of America. 93: 734-8. PMID 8570625 DOI: 10.1073/Pnas.93.2.734  1
1995 Brown JH, Jardetzky TS, Stern LJ, Gorga JC, Strominger JL, Wiley DC. Human class II MHC molecule HLA-DR1: X-ray structure determined from three crystal forms. Acta Crystallographica. Section D, Biological Crystallography. 51: 946-61. PMID 15299764 DOI: 10.1107/S0907444995002289  1
1995 Booth PJ, Flitsch SL, Stern LJ, Greenhalgh DA, Kim PS, Khorana HG. Intermediates in the folding of the membrane protein bacteriorhodopsin. Nature Structural Biology. 2: 139-43. PMID 7749918 DOI: 10.1038/Nsb0295-139  1
1995 Vogt AB, Stern LJ, Amshoff C, Dobberstein B, Hämmerling GJ, Kropshofer H. Interference of distinct invariant chain regions with superantigen contact area and antigenic peptide binding groove of HLA-DR. Journal of Immunology (Baltimore, Md. : 1950). 155: 4757-65. PMID 7594477  1
1995 Kropshofer H, Vogt AB, Stern LJ, Hämmerling GJ. Self-release of CLIP in peptide loading of HLA-DR molecules. Science (New York, N.Y.). 270: 1357-9. PMID 7481823 DOI: 10.1126/Science.270.5240.1357  1
1994 Sherman MA, Runnels HA, Moore JC, Stern LJ, Jensen PE. Membrane interactions influence the peptide binding behavior of DR1. The Journal of Experimental Medicine. 179: 229-34. PMID 8270868 DOI: 10.1084/jem.179.1.229  1
1994 Seth A, Stern LJ, Ottenhoff TH, Engel I, Owen MJ, Lamb JR, Klausner RD, Wiley DC. Binary and ternary complexes between T-cell receptor, class II MHC and superantigen in vitro. Nature. 369: 324-7. PMID 8183371 DOI: 10.1038/369324A0  1
1994 Jardetzky TS, Brown JH, Gorga JC, Stern LJ, Urban RG, Chi YI, Stauffacher C, Strominger JL, Wiley DC. Three-dimensional structure of a human class II histocompatibility molecule complexed with superantigen. Nature. 368: 711-8. PMID 8152483 DOI: 10.1038/368711A0  1
1994 Stern LJ, Brown JH, Jardetzky TS, Gorga JC, Urban RG, Strominger JL, Wiley DC. Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide. Nature. 368: 215-21. PMID 8145819 DOI: 10.1038/368215A0  1
1994 Stern LJ, Wiley DC. Antigenic peptide binding by class I and class II histocompatibility proteins. Structure (London, England : 1993). 2: 245-51. PMID 8087551 DOI: 10.1016/S0969-2126(00)00026-5  1
1994 Sadegh-Nasseri S, Stern LJ, Wiley DC, Germain RN. MHC class II function preserved by low-affinity peptide interactions preceding stable binding. Nature. 370: 647-50. PMID 8065450 DOI: 10.1038/370647A0  1
1994 Stern LJ, Wiley DC. Antigenic peptide binding by class I and class II histocompatibility proteins. Behring Institute Mitteilungen. 1-10. PMID 7998902  1
1993 Zhang YN, el-Sayed MA, Stern LJ, Marti T, Mogi T, Khorana HG. Effects of mutagenetic substitution of prolines on the rate of deprotonation and reprotonation of the Schiff base during the photocycle of bacteriorhodopsin. Photochemistry and Photobiology. 57: 1027-31. PMID 8367532 DOI: 10.1111/J.1751-1097.1993.Tb02966.X  1
1993 Brown JH, Jardetzky TS, Gorga JC, Stern LJ, Urban RG, Strominger JL, Wiley DC. Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1. Nature. 364: 33-9. PMID 8316295 DOI: 10.1038/364033A0  1
1992 Chicz RM, Urban RG, Lane WS, Gorga JC, Stern LJ, Vignali DA, Strominger JL. Predominant naturally processed peptides bound to HLA-DR1 are derived from MHC-related molecules and are heterogeneous in size. Nature. 358: 764-8. PMID 1380674 DOI: 10.1038/358764A0  1
1992 Stern LJ, Wiley DC. The human class II MHC protein HLA-DR1 assembles as empty alpha beta heterodimers in the absence of antigenic peptide. Cell. 68: 465-77. PMID 1371238 DOI: 10.1016/0092-8674(92)90184-E  1
1991 Lin GC, el-Sayed MA, Marti T, Stern LJ, Mogi T, Khorana HG. Effects of individual genetic substitutions of arginine residues on the deprotonation and reprotonation kinetics of the Schiff base during the bacteriorhodopsin photocycle. Biophysical Journal. 60: 172-8. PMID 1883936 DOI: 10.1016/S0006-3495(91)82040-9  1
1990 Jang DJ, el-Sayed MA, Stern LJ, Mogi T, Khorana HG. Effect of genetic modification of tyrosine-185 on the proton pump and the blue-to-purple transition in bacteriorhodopsin. Proceedings of the National Academy of Sciences of the United States of America. 87: 4103-7. PMID 2349220 DOI: 10.1073/Pnas.87.11.4103  1
1990 Du JJ, el-Sayed MA, Stern LJ, Mogi T, Khorana HG. Sensitivity of the retinal circular dichroism of bacteriorhodopsin to the mutagenetic single substitution of amino acids: tyrosine. Febs Letters. 262: 155-8. PMID 2185945 DOI: 10.1016/0014-5793(90)80178-L  1
1990 Rothschild KJ, He YW, Mogi T, Marti T, Stern LJ, Khorana HG. Vibrational spectroscopy of bacteriorhodopsin mutants: evidence for the interaction of proline-186 with the retinylidene chromophore. Biochemistry. 29: 5954-60. PMID 2166567 DOI: 10.1021/Bi00477A011  1
1990 Otto H, Marti T, Holz M, Mogi T, Stern LJ, Engel F, Khorana HG, Heyn MP. Substitution of amino acids Asp-85, Asp-212, and Arg-82 in bacteriorhodopsin affects the proton release phase of the pump and the pK of the Schiff base. Proceedings of the National Academy of Sciences of the United States of America. 87: 1018-22. PMID 2153966 DOI: 10.1073/Pnas.87.3.1018  1
1989 Rothschild KJ, Gray D, Mogi T, Marti T, Braiman MS, Stern LJ, Khorana HG. Vibrational spectroscopy of bacteriorhodopsin mutants: chromophore isomerization perturbs tryptophan-86. Biochemistry. 28: 7052-9. PMID 2819048 DOI: 10.1021/Bi00443A041  1
1989 Rothschild KJ, Braiman MS, Mogi T, Stern LJ, Khorana HG. Conserved amino acids in F-helix of bacteriorhodopsin form part of a retinal binding pocket. Febs Letters. 250: 448-52. PMID 2753143 DOI: 10.1016/0014-5793(89)80774-4  1
1989 Brouillette CG, McMichens RB, Stern LJ, Khorana HG. Structure and thermal stability of monomeric bacteriorhodopsin in mixed phospholipid/detergent micelles. Proteins. 5: 38-46. PMID 2748571 DOI: 10.1002/prot.340050106  1
1989 Stern LJ, Ahl PL, Marti T, Mogi T, Duñach M, Berkowitz S, Rothschild KJ, Khorana HG. Substitution of membrane-embedded aspartic acids in bacteriorhodopsin causes specific changes in different steps of the photochemical cycle. Biochemistry. 28: 10035-42. PMID 2575917  1
1989 Ahl PL, Stern LJ, Mogi T, Khorana HG, Rothschild KJ. Substitution of amino acids in helix F of bacteriorhodopsin: effects on the photochemical cycle. Biochemistry. 28: 10028-34. PMID 2575916 DOI: 10.1021/bi00452a022  1
1989 Stern LJ, Khorana HG. Structure-function studies on bacteriorhodopsin. X. Individual substitutions of arginine residues by glutamine affect chromophore formation, photocycle, and proton translocation. The Journal of Biological Chemistry. 264: 14202-8. PMID 2547788  1
1989 Mogi T, Stern LJ, Chao BH, Khorana HG. Structure-function studies on bacteriorhodopsin. VIII. Substitutions of the membrane-embedded prolines 50, 91, and 186: the effects are determined by the substituting amino acids. The Journal of Biological Chemistry. 264: 14192-6. PMID 2547786  1
1988 Mogi T, Stern LJ, Marti T, Chao BH, Khorana HG. Aspartic acid substitutions affect proton translocation by bacteriorhodopsin. Proceedings of the National Academy of Sciences of the United States of America. 85: 4148-52. PMID 3288985 DOI: 10.1073/Pnas.85.12.4148  1
1988 Braiman M, Bubis J, Doi T, Chen HB, Flitsch SL, Franke RR, Gilles-Gonzalez MA, Graham RM, Karnik SS, Khorana HG. Studies on light transduction by bacteriorhodopsin and rhodopsin. Cold Spring Harbor Symposia On Quantitative Biology. 53: 355-64. PMID 3076084 DOI: 10.1101/Sqb.1988.053.01.043  1
1988 Ahl PL, Stern LJ, Düring D, Mogi T, Khorana HG, Rothschild KJ. Effects of amino acid substitutions in the F helix of bacteriorhodopsin. Low temperature ultraviolet/visible difference spectroscopy. The Journal of Biological Chemistry. 263: 13594-601. PMID 3047127  1
1988 Braiman MS, Mogi T, Marti T, Stern LJ, Khorana HG, Rothschild KJ. Vibrational spectroscopy of bacteriorhodopsin mutants: light-driven proton transport involves protonation changes of aspartic acid residues 85, 96, and 212. Biochemistry. 27: 8516-20. PMID 2851326 DOI: 10.1021/Bi00423A002  1
1988 Braiman MS, Mogi T, Stern LJ, Hackett NR, Chao BH, Khorana HG, Rothschild KJ. Vibrational spectroscopy of bacteriorhodopsin mutants: I. Tyrosine-185 protonates and deprotonates during the photocycle. Proteins. 3: 219-29. PMID 2843849 DOI: 10.1002/Prot.340030403  1
1987 Hackett NR, Stern LJ, Chao BH, Kronis KA, Khorana HG. Structure-function studies on bacteriorhodopsin. V. Effects of amino acid substitutions in the putative helix F. The Journal of Biological Chemistry. 262: 9277-84. PMID 3597412  1
1987 Braiman MS, Stern LJ, Chao BH, Khorana HG. Structure-function studies on bacteriorhodopsin. IV. Purification and renaturation of bacterio-opsin polypeptide expressed in Escherichia coli. The Journal of Biological Chemistry. 262: 9271-6. PMID 3298254  1
1987 Mogi T, Stern LJ, Hackett NR, Khorana HG. Bacteriorhodopsin mutants containing single tyrosine to phenylalanine substitutions are all active in proton translocation. Proceedings of the National Academy of Sciences of the United States of America. 84: 5595-9. PMID 3039495 DOI: 10.1073/Pnas.84.16.5595  1
1985 Pyrz JW, Roe AL, Stern LJ, Que L. Model studies of iron-tyrosinate proteins Journal of the American Chemical Society. 107: 614-620. DOI: 10.1002/Chin.198524040  1
1979 Brazin SA, Stern LJ, Johnson WT. Unilateral blepharochalasis. Archives of Dermatology. 115: 479-81. PMID 434876 DOI: 10.1001/archderm.1979.04010040057018  1
1968 Stern LJ. The development of a new bituminous stabilizer Preprints. 13: C31-C40.  1
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