Igor Prudovsky - Publications

Affiliations: 
The University of Maine, Orono, ME, United States 
Area:
Chemical Engineering, Biomedical Engineering, General Biophysics

65 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Keeley T, Kirov A, Koh WY, Demambro V, Bergquist I, Cotter J, Caradonna P, Siviski ME, Best B, Henderson T, Rosen CJ, Liaw L, Prudovsky I, Small DJ. Resistance to visceral obesity is associated with increased locomotion in mice expressing an endothelial cell-specific fibroblast growth factor 1 transgene. Physiological Reports. 7: e14034. PMID 30972920 DOI: 10.14814/Phy2.14034  0.352
2019 Prudovsky I, Carter D, Kacer D, Palmeri M, Soul T, Kumpel C, Pyburn K, Barrett K, DeMambro V, Alexandrov I, Brandina I, Kramer R, Rappold J. Tranexamic acid suppresses the release of mitochondrial DNA, protects the endothelial monolayer and enhances oxidative phosphorylation. Journal of Cellular Physiology. PMID 30941770 DOI: 10.1002/Jcp.28603  0.311
2018 Prudovsky I, Anunciado-Koza RP, Jacobs CG, Kacer D, Siviski ME, Koza RA. Mesoderm-specific transcript localization in the ER and ER-lipid droplet interface supports a role in adipocyte hypertrophy. Journal of Cellular Biochemistry. 119: 2636-2645. PMID 29058774 DOI: 10.1002/Jcb.26429  0.34
2016 Prudovsky I, Kacer D, Davis J, Shah V, Jayanthi S, Huber I, Dakshinamurthy R, Ganter O, Soldi R, Neivandt DJ, Guvench O, Suresh Kumar TK. FGF1 folding is critical for its nonclassical release. Biochemistry. PMID 26836284 DOI: 10.1021/Acs.Biochem.5B01341  0.456
2015 Poole A, Kacer D, Cooper E, Tarantini F, Prudovsky I. Sustained Inhibition of Proliferative Response After Transient FGF Stimulation is Mediated by Interleukin 1 Signaling. Journal of Cellular Physiology. PMID 26218437 DOI: 10.1002/Jcp.25111  0.402
2015 Yang X, Liaw L, Prudovsky I, Brooks PC, Vary C, Oxburgh L, Friesel R. Fibroblast growth factor signaling in the vasculature. Current Atherosclerosis Reports. 17: 509. PMID 25813213 DOI: 10.1007/S11883-015-0509-6  0.391
2015 Kirov A, Kacer D, Conley BA, Vary CP, Prudovsky I. AHNAK2 Participates in the Stress-Induced Nonclassical FGF1 Secretion Pathway. Journal of Cellular Biochemistry. 116: 1522-31. PMID 25560297 DOI: 10.1002/Jcb.25047  0.434
2014 Jayanthi S, Kathir KM, Rajalingam D, Furr M, Daily A, Thurman R, Rutherford L, Chandrashekar R, Adams P, Prudovsky I, Kumar TK. Copper binding affinity of the C2B domain of synaptotagmin-1 and its potential role in the nonclassical secretion of acidic fibroblast growth factor. Biochimica Et Biophysica Acta. 1844: 2155-2163. PMID 25224745 DOI: 10.1016/J.Bbapap.2014.09.008  0.377
2014 Poole A, Knowland N, Cooper E, Cole R, Wang H, Booth L, Kacer D, Tarantini F, Friesel R, Prudovsky I. Transitory FGF treatment results in the long-lasting suppression of the proliferative response to repeated FGF stimulation. Journal of Cellular Biochemistry. 115: 874-88. PMID 24375433 DOI: 10.1002/Jcb.24731  0.392
2013 Prudovsky I. Nonclassically Secreted Regulators of Angiogenesis. Angiology: Open Access. 1: 1000101. PMID 24511556 DOI: 10.4172/2329-9495.1000101  0.381
2013 Gong Y, Yang X, He Q, Gower L, Prudovsky I, Vary CP, Brooks PC, Friesel RE. Sprouty4 regulates endothelial cell migration via modulating integrin β3 stability through c-Src. Angiogenesis. 16: 861-75. PMID 23955631 DOI: 10.1007/S10456-013-9361-X  0.39
2013 Danza G, Di Serio C, Ambrosio MR, Sturli N, Lonetto G, Rosati F, Rocca BJ, Ventimiglia G, del Vecchio MT, Prudovsky I, Marchionni N, Tarantini F. Notch3 is activated by chronic hypoxia and contributes to the progression of human prostate cancer. International Journal of Cancer. Journal International Du Cancer. 133: 2577-86. PMID 23729168 DOI: 10.1002/Ijc.28293  0.332
2013 Prudovsky I, Kumar TK, Sterling S, Neivandt D. Protein-phospholipid interactions in nonclassical protein secretion: problem and methods of study. International Journal of Molecular Sciences. 14: 3734-72. PMID 23396106 DOI: 10.3390/Ijms14023734  0.396
2013 Lopez-Castejon G, Luheshi NM, Compan V, High S, Whitehead RC, Flitsch S, Kirov A, Prudovsky I, Swanton E, Brough D. Deubiquitinases regulate the activity of caspase-1 and interleukin-1β secretion via assembly of the inflammasome. The Journal of Biological Chemistry. 288: 2721-33. PMID 23209292 DOI: 10.1074/Jbc.M112.422238  0.342
2012 Meng H, Zhang X, Yu G, Lee SJ, Chen YE, Prudovsky I, Wang MM. Biochemical characterization and cellular effects of CADASIL mutants of NOTCH3. Plos One. 7: e44964. PMID 23028706 DOI: 10.1371/Journal.Pone.0044964  0.329
2012 Kirov A, Duarte M, Guay J, Karolak M, Yan C, Oxburgh L, Prudovsky I. Transgenic expression of nonclassically secreted FGF suppresses kidney repair. Plos One. 7: e36485. PMID 22606265 DOI: 10.1371/Journal.Pone.0036485  0.381
2012 Danza G, Di Serio C, Rosati F, Lonetto G, Sturli N, Kacer D, Pennella A, Ventimiglia G, Barucci R, Piscazzi A, Prudovsky I, Landriscina M, Marchionni N, Tarantini F. Notch signaling modulates hypoxia-induced neuroendocrine differentiation of human prostate cancer cells. Molecular Cancer Research : McR. 10: 230-8. PMID 22172337 DOI: 10.1158/1541-7786.Mcr-11-0296  0.352
2012 Kirov A, Al-Hashimi H, Solomon P, Mazur C, Thorpe PE, Sims PJ, Tarantini F, Kumar TK, Prudovsky I. Phosphatidylserine externalization and membrane blebbing are involved in the nonclassical export of FGF1. Journal of Cellular Biochemistry. 113: 956-66. PMID 22034063 DOI: 10.1002/Jcb.23425  0.432
2011 Kacer D, McIntire C, Kirov A, Kany E, Roth J, Liaw L, Small D, Friesel R, Basilico C, Tarantini F, Verdi J, Prudovsky I. Regulation of non-classical FGF1 release and FGF-dependent cell transformation by CBF1-mediated notch signaling. Journal of Cellular Physiology. 226: 3064-75. PMID 21302306 DOI: 10.1002/Jcp.22663  0.489
2010 Karaczyn A, Bani-Yaghoub M, Tremblay R, Kubu C, Cowling R, Adams TL, Prudovsky I, Spicer D, Friesel R, Vary C, Verdi JM. Two novel human NUMB isoforms provide a potential link between development and cancer. Neural Development. 5: 31. PMID 21122105 DOI: 10.1186/1749-8104-5-31  0.371
2010 Massi D, Landriscina M, Piscazzi A, Cosci E, Kirov A, Paglierani M, Di Serio C, Mourmouras V, Fumagalli S, Biagioli M, Prudovsky I, Miracco C, Santucci M, Marchionni N, Tarantini F. S100A13 is a new angiogenic marker in human melanoma. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 23: 804-13. PMID 20208480 DOI: 10.1038/Modpathol.2010.54  0.362
2010 Kathir KM, Gao L, Rajalingam D, Daily AE, Brixey S, Liu H, Davis D, Adams P, Prudovsky I, Kumar TK. NMR characterization of copper and lipid interactions of the C2B domain of synaptotagmin I-relevance to the non-classical secretion of the human acidic fibroblast growth factor (hFGF-1). Biochimica Et Biophysica Acta. 1798: 297-302. PMID 19835837 DOI: 10.1016/J.Bbamem.2009.09.024  0.346
2009 Mouta-Bellum C, Kirov A, Miceli-Libby L, Mancini ML, Petrova TV, Liaw L, Prudovsky I, Thorpe PE, Miura N, Cantley LC, Alitalo K, Fruman DA, Vary CP. Organ-specific lymphangiectasia, arrested lymphatic sprouting, and maturation defects resulting from gene-targeting of the PI3K regulatory isoforms p85alpha, p55alpha, and p50alpha. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 238: 2670-9. PMID 19705443 DOI: 10.1002/Dvdy.22078  0.366
2009 Graziani I, Doyle A, Sterling S, Kirov A, Tarantini F, Landriscina M, Kumar TK, Neivandt D, Prudovsky I. Protein folding does not prevent the nonclassical export of FGF1 and S100A13. Biochemical and Biophysical Research Communications. 381: 350-4. PMID 19233122 DOI: 10.1016/J.Bbrc.2009.02.061  0.418
2008 Duarte M, Kolev V, Kacer D, Mouta-Bellum C, Soldi R, Graziani I, Kirov A, Friesel R, Liaw L, Small D, Verdi J, Maciag T, Prudovsky I. Novel cross-talk between three cardiovascular regulators: thrombin cleavage fragment of Jagged1 induces fibroblast growth factor 1 expression and release. Molecular Biology of the Cell. 19: 4863-74. PMID 18784255 DOI: 10.1091/Mbc.E07-12-1237  0.479
2008 Urs S, Roudabush A, O'Neill CF, Pinz I, Prudovsky I, Kacer D, Tang Y, Liaw L, Small D. Soluble forms of the Notch ligands Delta1 and Jagged1 promote in vivo tumorigenicity in NIH3T3 fibroblasts with distinct phenotypes. The American Journal of Pathology. 173: 865-78. PMID 18688026 DOI: 10.2353/Ajpath.2008.080006  0.371
2008 Lee CW, Raskett CM, Prudovsky I, Altieri DC. Molecular dependence of estrogen receptor-negative breast cancer on a notch-survivin signaling axis. Cancer Research. 68: 5273-81. PMID 18593928 DOI: 10.1158/0008-5472.Can-07-6673  0.329
2008 Di Serio C, Doria L, Pellerito S, Prudovsky I, Micucci I, Massi D, Landriscina M, Marchionni N, Masotti G, Tarantini F. The release of fibroblast growth factor-1 from melanoma cells requires copper ions and is mediated by phosphatidylinositol 3-kinase/Akt intracellular signaling pathway. Cancer Letters. 267: 67-74. PMID 18400376 DOI: 10.1016/J.Canlet.2008.03.001  0.426
2008 Prudovsky I, Tarantini F, Landriscina M, Neivandt D, Soldi R, Kirov A, Small D, Kathir KM, Rajalingam D, Kumar TK. Secretion without Golgi. Journal of Cellular Biochemistry. 103: 1327-43. PMID 17786931 DOI: 10.1002/Jcb.21513  0.437
2007 Kathir KM, Ibrahim K, Rajalingam D, Prudovsky I, Yu C, Kumar TK. S100A13-lipid interactions-role in the non-classical release of the acidic fibroblast growth factor. Biochimica Et Biophysica Acta. 1768: 3080-9. PMID 17991455 DOI: 10.1016/J.Bbamem.2007.09.007  0.353
2007 Nikopoulos GN, Duarte M, Kubu CJ, Bellum S, Friesel R, Maciag T, Prudovsky I, Verdi JM. Soluble Jagged1 attenuates lateral inhibition, allowing for the clonal expansion of neural crest stem cells. Stem Cells (Dayton, Ohio). 25: 3133-42. PMID 17761753 DOI: 10.1634/Stemcells.2007-0327  0.368
2007 Soldi R, Mandinova A, Venkataraman K, Hla T, Vadas M, Pitson S, Duarte M, Graziani I, Kolev V, Kacer D, Kirov A, Maciag T, Prudovsky I. Sphingosine kinase 1 is a critical component of the copper-dependent FGF1 export pathway. Experimental Cell Research. 313: 3308-18. PMID 17643421 DOI: 10.1016/J.Yexcr.2007.05.031  0.389
2007 Rajalingam D, Graziani I, Prudovsky I, Yu C, Kumar TK. Relevance of partially structured states in the non-classical secretion of acidic fibroblast growth factor. Biochemistry. 46: 9225-38. PMID 17636870 DOI: 10.1021/Bi7002586  0.339
2007 Di Serio C, Pellerito S, Duarte M, Massi D, Naldini A, Cirino G, Prudovsky I, Santucci M, Geppetti P, Marchionni N, Masotti G, Tarantini F. Protease-activated receptor 1-selective antagonist SCH79797 inhibits cell proliferation and induces apoptosis by a protease-activated receptor 1-independent mechanism. Basic & Clinical Pharmacology & Toxicology. 101: 63-9. PMID 17577318 DOI: 10.1111/J.1742-7843.2007.00078.X  0.347
2006 Duarte M, Kolev V, Soldi R, Kirov A, Graziani I, Oliveira SM, Kacer D, Friesel R, Maciag T, Prudovsky I. Thrombin induces rapid PAR1-mediated non-classical FGF1 release. Biochemical and Biophysical Research Communications. 350: 604-9. PMID 17027650 DOI: 10.1016/J.Bbrc.2006.09.107  0.463
2006 Graziani I, Bagalá C, Duarte M, Soldi R, Kolev V, Tarantini F, Kumar TK, Doyle A, Neivandt D, Yu C, Maciag T, Prudovsky I. Release of FGF1 and p40 synaptotagmin 1 correlates with their membrane destabilizing ability. Biochemical and Biophysical Research Communications. 349: 192-9. PMID 16930531 DOI: 10.1016/J.Bbrc.2006.08.021  0.434
2006 Landriscina M, Schinzari G, Di Leonardo G, Quirino M, Cassano A, D'Argento E, Lauriola L, Scerrati M, Prudovsky I, Barone C. S100A13, a new marker of angiogenesis in human astrocytic gliomas. Journal of Neuro-Oncology. 80: 251-9. PMID 16773219 DOI: 10.1007/S11060-006-9189-Y  0.408
2006 Sivaraja V, Kumar TK, Rajalingam D, Graziani I, Prudovsky I, Yu C. Copper binding affinity of S100A13, a key component of the FGF-1 nonclassical copper-dependent release complex. Biophysical Journal. 91: 1832-43. PMID 16766622 DOI: 10.1529/Biophysj.105.079988  0.32
2005 Rajalingam D, Kumar TK, Soldi R, Graziani I, Prudovsky I, Yu C. Molecular mechanism of inhibition of nonclassical FGF-1 export. Biochemistry. 44: 15472-9. PMID 16300395 DOI: 10.1021/Bi0516071  0.429
2005 Omoto A, Kawahito Y, Prudovsky I, Tubouchi Y, Kimura M, Ishino H, Wada M, Yoshida M, Kohno M, Yoshimura R, Yoshikawa T, Sano H. Copper chelation with tetrathiomolybdate suppresses adjuvant-induced arthritis and inflammation-associated cachexia in rats. Arthritis Research & Therapy. 7: R1174-82. PMID 16277669 DOI: 10.1186/Ar1801  0.31
2005 Kolev V, Kacer D, Trifonova R, Small D, Duarte M, Soldi R, Graziani I, Sideleva O, Larman B, Maciag T, Prudovsky I. The intracellular domain of Notch ligand Delta1 induces cell growth arrest. Febs Letters. 579: 5798-5802. PMID 16225865 DOI: 10.1016/J.Febslet.2005.09.042  0.398
2005 Sivaraja V, Kumar TK, Prudovsky I, Yu C. Three-dimensional solution structure of a unique S100 protein. Biochemical and Biophysical Research Communications. 335: 1140-8. PMID 16122705 DOI: 10.1016/J.Bbrc.2005.08.005  0.341
2004 Andreeva V, Prudovsky I, Thomas M. Stimulation of quiescent cells by individual polypeptide growth factors is limited to one cell cycle. European Journal of Cell Biology. 83: 327-35. PMID 15503856 DOI: 10.1078/0171-9335-00390  0.402
2004 Doyle AW, Fick J, Himmelhaus M, Eck W, Graziani I, Prudovsky I, Grunze M, Maciag T, Neivandt DJ. Protein deformation of lipid hybrid bilayer membranes studied by sum frequency generation vibrational spectroscopy. Langmuir : the Acs Journal of Surfaces and Colloids. 20: 8961-5. PMID 15461473 DOI: 10.1021/La0484220  0.316
2004 Trifonova R, Small D, Kacer D, Kovalenko D, Kolev V, Mandinova A, Soldi R, Liaw L, Prudovsky I, Maciag T. The non-transmembrane form of Delta1, but not of Jagged1, induces normal migratory behavior accompanied by fibroblast growth factor receptor 1-dependent transformation. The Journal of Biological Chemistry. 279: 13285-8. PMID 14769803 DOI: 10.1074/Jbc.C300564200  0.394
2004 Peng H, Sahni A, Fay P, Bellum S, Prudovsky I, Maciag T, Francis CW. Identification of a binding site on human FGF-2 for fibrinogen. Blood. 103: 2114-20. PMID 14630795 DOI: 10.1182/Blood-2003-08-2638  0.361
2003 Prudovsky I, Mandinova A, Soldi R, Bagala C, Graziani I, Landriscina M, Tarantini F, Duarte M, Bellum S, Doherty H, Maciag T. The non-classical export routes: FGF1 and IL-1alpha point the way. Journal of Cell Science. 116: 4871-81. PMID 14625381 DOI: 10.1242/Jcs.00872  0.362
2003 Bagalá C, Kolev V, Mandinova A, Soldi R, Mouta C, Graziani I, Prudovsky I, Maciag T. The alternative translation of synaptotagmin 1 mediates the non-classical release of FGF1. Biochemical and Biophysical Research Communications. 310: 1041-7. PMID 14559220 DOI: 10.1016/J.Bbrc.2003.09.119  0.341
2003 Mandinov L, Mandinova A, Kyurkchiev S, Kyurkchiev D, Kehayov I, Kolev V, Soldi R, Bagala C, de Muinck ED, Lindner V, Post MJ, Simons M, Bellum S, Prudovsky I, Maciag T. Copper chelation represses the vascular response to injury. Proceedings of the National Academy of Sciences of the United States of America. 100: 6700-5. PMID 12754378 DOI: 10.1073/Pnas.1231994100  0.345
2003 Mandinova A, Soldi R, Graziani I, Bagala C, Bellum S, Landriscina M, Tarantini F, Prudovsky I, Maciag T. S100A13 mediates the copper-dependent stress-induced release of IL-1alpha from both human U937 and murine NIH 3T3 cells. Journal of Cell Science. 116: 2687-96. PMID 12746488 DOI: 10.1242/Jcs.00471  0.386
2003 Small D, Kovalenko D, Soldi R, Mandinova A, Kolev V, Trifonova R, Bagala C, Kacer D, Battelli C, Liaw L, Prudovsky I, Maciag T. Notch activation suppresses fibroblast growth factor-dependent cellular transformation. The Journal of Biological Chemistry. 278: 16405-13. PMID 12598523 DOI: 10.1074/Jbc.M300464200  0.447
2002 Prudovsky I, Bagala C, Tarantini F, Mandinova A, Soldi R, Bellum S, Maciag T. The intracellular translocation of the components of the fibroblast growth factor 1 release complex precedes their assembly prior to export. The Journal of Cell Biology. 158: 201-8. PMID 12135982 DOI: 10.1083/Jcb.200203084  0.423
2002 Prudovsky I, Popov K, Akimov S, Serov S, Zelenin A, Meinhardt G, Baier P, Sohn C, Hass R. Antisense CD11b integrin inhibits the development of a differentiated monocyte/macrophage phenotype in human leukemia cells. European Journal of Cell Biology. 81: 36-42. PMID 11893077 DOI: 10.1078/0171-9335-00219  0.359
2001 Lindner V, Booth C, Prudovsky I, Small D, Maciag T, Liaw L. Members of the Jagged/Notch gene families are expressed in injured arteries and regulate cell phenotype via alterations in cell matrix and cell-cell interaction. The American Journal of Pathology. 159: 875-83. PMID 11549580 DOI: 10.1016/S0002-9440(10)61763-4  0.397
2001 Mouta Carreira C, Landriscina M, Bellum S, Prudovsky I, Maciag T. The comparative release of FGF1 by hypoxia and temperature stress. Growth Factors (Chur, Switzerland). 18: 277-85. PMID 11519826 DOI: 10.3109/08977190109029116  0.397
2001 Landriscina M, Bagalá C, Mandinova A, Soldi R, Micucci I, Bellum S, Prudovsky I, Maciag T. Copper induces the assembly of a multiprotein aggregate implicated in the release of fibroblast growth factor 1 in response to stress. The Journal of Biological Chemistry. 276: 25549-57. PMID 11432880 DOI: 10.1074/Jbc.M102925200  0.371
2001 Small D, Kovalenko D, Kacer D, Liaw L, Landriscina M, Di Serio C, Prudovsky I, Maciag T. Soluble Jagged 1 represses the function of its transmembrane form to induce the formation of the Src-dependent chord-like phenotype. The Journal of Biological Chemistry. 276: 32022-30. PMID 11427524 DOI: 10.1074/Jbc.M100933200  0.422
2001 Landriscina M, Soldi R, Bagalá C, Micucci I, Bellum S, Tarantini F, Prudovsky I, Maciag T. S100A13 participates in the release of fibroblast growth factor 1 in response to heat shock in vitro. The Journal of Biological Chemistry. 276: 22544-52. PMID 11410600 DOI: 10.1074/Jbc.M100546200  0.439
2001 Tarantini F, Micucci I, Bellum S, Landriscina M, Garfinkel S, Prudovsky I, Maciag T. The precursor but not the mature form of IL1alpha blocks the release of FGF1 in response to heat shock. The Journal of Biological Chemistry. 276: 5147-51. PMID 11087725 DOI: 10.1074/Jbc.C000714200  0.427
2000 Prudovsky I, Landriscina M, Soldi R, Bellum S, Small D, Andreeva V, Maciag T. Fusions to members of fibroblast growth factor gene family to study nuclear translocation and nonclassic exocytosis. Methods in Enzymology. 327: 369-82. PMID 11044997 DOI: 10.1016/S0076-6879(00)27290-X  0.409
2000 Landriscina M, Prudovsky I, Mouta Carreira C, Soldi R, Tarantini F, Maciag T. Amlexanox reversibly inhibits cell migration and proliferation and induces the Src-dependent disassembly of actin stress fibers in vitro. The Journal of Biological Chemistry. 275: 32753-62. PMID 10921913 DOI: 10.1074/Jbc.M002336200  0.409
2000 Wong MK, Prudovsky I, Vary C, Booth C, Liaw L, Mousa S, Small D, Maciag T. A non-transmembrane form of Jagged-1 regulates the formation of matrix-dependent chord-like structures. Biochemical and Biophysical Research Communications. 268: 853-9. PMID 10679295 DOI: 10.1006/Bbrc.2000.2173  0.439
1997 Vartanian A, Prudovsky I, Suzuki H, Pra ID, Kisselev L. Opposite effects of cell differentiation and apoptosis on Ap3A/Ap4A ratio in human cell cultures Febs Letters. 415: 160-162. PMID 9350987 DOI: 10.1016/S0014-5793(97)01086-7  0.342
1997 Hass R, Prudovsky I, Kruhøffer M. Differential effects of phorbol ester on signaling and gene expression in human leukemia cells. Leukemia Research. 21: 589-94. PMID 9301678 DOI: 10.1016/S0145-2126(97)00010-6  0.341
1994 Maciag T, Zhan X, Garfinkel S, Friedman S, Prudovsky I, Jackson A, Wessendorf J, Hu X, Gamble S, Shi J. Novel mechanisms of fibroblast growth factor 1 function. Recent Progress in Hormone Research. 49: 105-23. PMID 7511824 DOI: 10.1016/B978-0-12-571149-4.50009-X  0.409
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