Gustavo Rosania - Related publications

University of Michigan, Ann Arbor, Ann Arbor, MI 
Pharmacy, Organic Chemistry
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Lin CY, Wu HY, Hsu YL, Cheng TR, Liu JH, Huang RJ, Hsiao TH, Wang CJ, Hung PF, Lan A, Pan SH, Chein R, Wong CH, Yang PC. Suppression of Drug-Resistant Non-Small-Cell Lung Cancer with Inhibitors Targeting Minichromosomal Maintenance Protein. Journal of Medicinal Chemistry. PMID 32125853 DOI: 10.1021/acs.jmedchem.9b01783   
2020 Ghinet A, Thuru X, Floquet E, Dubois J, Farce A, Rigo B. Enhanced antitumor potential induced by chloroacetate-loaded benzophenones acting as fused tubulin-pyruvate dehydrogenase kinase 1 (PDHK1) ligands. Bioorganic Chemistry. 96: 103643. PMID 32035298 DOI: 10.1016/j.bioorg.2020.103643   
2020 Bae SY, Liao L, Park SH, Kim WK, Shin J, Lee SK. Antitumor Activity of Asperphenin A, a Lipopeptidyl Benzophenone from Marine-Derived sp. Fungus, by Inhibiting Tubulin Polymerization in Colon Cancer Cells. Marine Drugs. 18. PMID 32069904 DOI: 10.3390/md18020110   
2020 Xin ZH, Meng YL, Jiang WJ, Li YP, Ge LP, Zhang CH, Liu LN, Kang YF. Finding an efficient tetramethylated hydroxydiethylene of resveratrol analogue for potential anticancer agent. Bmc Chemistry. 14: 13. PMID 32099972 DOI: 10.1186/s13065-020-00667-5   
2020 Khathayer F, Taylor MA, Ray SK. Synergism of 4HPR and SAHA increases anti-tumor actions in glioblastoma cells. Apoptosis : An International Journal On Programmed Cell Death. PMID 32006189 DOI: 10.1007/s10495-020-01590-9   
2020 Du X, He K, Huang Y, Xu Z, Kong M, Zhang J, Cao J, Teng L. Establishment of a novel human cell line retaining the characteristics of the original pancreatic adenocarcinoma, and evaluation of MEK as a therapeutic target. International Journal of Oncology. PMID 32124956 DOI: 10.3892/ijo.2020.4965   
2020 Kamal MA, Al-Zahrani MH, Khan SH, Khan MH, Al Subhi HA, Kuerban A, Aslam M, Al Abassi FA, Anwar F. Tubulin Proteins in Cancer Resistance: A review. Current Drug Metabolism. PMID 32101117 DOI: 10.2174/1389200221666200226123638   
2020 Zhao N, Yang F, Han L, Qu Y, Ge D, Zhang H. Development of Coumarin-Based Hydroxamates as Histone Deacetylase Inhibitors with Antitumor Activities. Molecules (Basel, Switzerland). 25. PMID 32046013 DOI: 10.3390/molecules25030717   
2020 Shen J, Li L, Yang T, Cohen PS, Sun G. Biphasic Mathematical Model of Cell-Drug Interaction That Separates Target-Specific and Off-Target Inhibition and Suggests Potent Targeted Drug Combinations for Multi-Driver Colorectal Cancer Cells. Cancers. 12. PMID 32069833 DOI: 10.3390/cancers12020436   
2020 Nawaz F, Alam O, Perwez A, Rizvi MA, Naim MJ, Siddiqui N, Pottoo FH, Jha M. 3'-(4-(Benzyloxy)phenyl)-1'-phenyl-5-(heteroaryl/aryl)-3,4-dihydro-1'H,2H-[3,4'-bipyrazole]-2-carboxamides as EGFR kinase inhibitors: Synthesis, anticancer evaluation, and molecular docking studies. Archiv Der Pharmazie. e1900262. PMID 32003485 DOI: 10.1002/ardp.201900262   
2020 Benítez D, Dibello E, Bonilla M, Comini MA. A simple, robust, and affordable bioluminescent assay for drug discovery against infective African trypanosomes. Drug Development Research. PMID 31958156 DOI: 10.1002/ddr.21634   
2020 Hernandes C, Miguita L, de Sales RO, Silva EP, Mendonça POR, Lorencini da Silva B, Klingbeil MFG, Mathor MB, Rangel EB, Marti LC, Coppede JDS, Nunes FD, Pereira AMS, Severino P. Anticancer Activities of the Quinone-Methide Triterpenes Maytenin and 22-β-hydroxymaytenin Obtained from Cultivated Roots Associated with Down-Regulation of miRNA-27a and miR-20a/miR-17-5p. Molecules (Basel, Switzerland). 25. PMID 32050628 DOI: 10.3390/molecules25030760   
2020 Oasa S, Vukojević V, Rigler R, Tsigelny IF, Changeux JP, Terenius L. A strategy for designing allosteric modulators of transcription factor dimerization. Proceedings of the National Academy of Sciences of the United States of America. PMID 31953259 DOI: 10.1073/pnas.1915531117   
2020 Guo L, Chen X, Chen W, Ma Q, Fan W, Zhang J, Dai B. Molecular hybrid design, synthesis, in vitro and in vivo anticancer evaluation, and mechanism of action of N-acylhydrazone linked, heterobivalent β-carbolines. Bioorganic Chemistry. 96: 103612. PMID 32007724 DOI: 10.1016/j.bioorg.2020.103612   
2020 Wang NY, Xu Y, Xiao KJ, Zuo WQ, Zhu YX, Hu R, Wang WL, Shi YJ, Yu LT, Liu ZH. Design, synthesis, and biological evaluation of 4,5-dihydro-[1,2,4]triazolo[4,3-f]pteridine derivatives as novel dual-PLK1/BRD4 inhibitors. European Journal of Medicinal Chemistry. 191: 112152. PMID 32088495 DOI: 10.1016/j.ejmech.2020.112152   
2020 Ke X, Qin Q, Deng T, Liao Y, Gao SJ. Heterogeneous Responses of Gastric Cancer Cell Lines to Tenovin-6 and Synergistic Effect with Chloroquine. Cancers. 12. PMID 32033497 DOI: 10.3390/cancers12020365   
2020 Goud NS, Kanth Makani VK, Pranay J, Alvala R, Qureshi IA, Kumar P, Bharath RD, Nagaraj C, Yerramsetty S, Pal-Bhadra M, Alvala M. Synthesis, F-radiolabeling and apoptosis inducing studies of novel 4, 7-disubstituted coumarins. Bioorganic Chemistry. 97: 103663. PMID 32106038 DOI: 10.1016/j.bioorg.2020.103663   
2020 Wang Y, Liao H, Zheng T, Wang J, Guo D, Lu Z, Li Z, Chen Y, Shen L, Zhang Y, Gao J. Conditionally reprogrammed colorectal cancer cells combined with mouse avatars identify synergy between EGFR and MEK or CDK4/6 inhibitors. American Journal of Cancer Research. 10: 249-262. PMID 32064165   
2020 Melnikova M, Wauer US, Mendus D, Hilger RA, Oliver TG, Mercer K, Gohlke BO, Erdmann K, Niederacher D, Neubauer H, Buderath P, Wimberger P, Kuhlmann JD, Thomale J. Diphenhydramine increases the therapeutic window for platinum drugs by simultaneously sensitizing tumor cells and protecting normal cells. Molecular Oncology. PMID 32037720 DOI: 10.1002/1878-0261.12648   
2020 Liu R, Deng X, Peng Y, Feng W, Xiong R, Zou Y, Lei X, Zheng X, Xie Z, Tang G. Synthesis and biological evaluation of novel 5,6,7-trimethoxy flavonoid salicylate derivatives as potential anti-tumor agents. Bioorganic Chemistry. 96: 103652. PMID 32059154 DOI: 10.1016/j.bioorg.2020.103652   
2020 Lin K, Rong Y, Chen D, Zhao Z, Bo H, Qiao A, Hao X, Wang J. Combination of Ruthenium Complex and Doxorubicin Synergistically Inhibits Cancer Cell Growth by Down-Regulating PI3K/AKT Signaling Pathway. Frontiers in Oncology. 10: 141. PMID 32133289 DOI: 10.3389/fonc.2020.00141   
2020 Daniyal M, Jian Y, Xiao F, Sheng W, Fan J, Xiao C, Wang Z, Liu B, Peng C, Yuhui Q, Wang W. Development of a nanodrug-delivery system, camouflaged by erythrocytes membrane for the chemo/phototherapy of cancer. Nanomedicine (London, England). PMID 32043430 DOI: 10.2217/nnm-2019-0454   
2020 Gaudio E, Tarantelli C, Spriano F, Guidetti F, Sartori G, Bordone R, Arribas AJ, Cascione L, Bigioni M, Merlino G, Fiascarelli A, Bressan A, Mensah AA, Golino G, Lucchini R, et al. Targeting CD205 with the antibody drug conjugate MEN1309/OBT076 is an active new therapeutic strategy in lymphoma models. Haematologica. PMID 31919082 DOI: 10.3324/haematol.2019.227215   
2020 Lerata MS, D'Souza S, Sibuyi NRS, Dube A, Meyer M, Samaai T, Antunes EM, Beukes DR. Encapsulation of Variabilin in Stearic Acid Solid Lipid Nanoparticles Enhances Its Anticancer Activity in Vitro. Molecules (Basel, Switzerland). 25. PMID 32074951 DOI: 10.3390/molecules25040830   
2020 Li J, Xiong X, Wang Z, Zhao Y, Shi Z, Zhao M, Ren T. In vitro high-throughput drug sensitivity screening with patient-derived primary cells as a guide for clinical practice in hepatocellular carcinoma-A retrospective evaluation. Clinics and Research in Hepatology and Gastroenterology. PMID 32014387 DOI: 10.1016/j.clinre.2020.01.003   
2020 Wang M, Tian C, Xue L, Li H, Cong J, Fang F, Yang J, Yuan M, Chen Y, Guo Y, Wang X, Liu J, Zhang Z. Design, synthesis and biological activity of N-substituted tetrahydropteroate analogs as non-classical antifolates against cobalamin-dependent methionine synthase and potential anticancer agents. European Journal of Medicinal Chemistry. 190: 112113. PMID 32058237 DOI: 10.1016/j.ejmech.2020.112113   
2020 Faraone I, Sinisgalli C, Ostuni A, Armentano MF, Carmosino M, Milella L, Russo D, Labanca F, Khan H. Astaxanthin anticancer effects are mediated through multiple molecular mechanisms: a systematic review. Pharmacological Research. 104689. PMID 32057895 DOI: 10.1016/j.phrs.2020.104689   
2020 Zwergel C, Fioravanti R, Stazi G, Sarno F, Battistelli C, Romanelli A, Nebbioso A, Mendes E, Paulo A, Strippoli R, Tripodi M, Pechalrieu D, Arimondo PB, De Luca T, Del Bufalo D, et al. Novel Quinoline Compounds Active in Cancer Cells through Coupled DNA Methyltransferase Inhibition and Degradation. Cancers. 12. PMID 32075099 DOI: 10.3390/cancers12020447   
2020 Oechsle CM, Showalter LE, Novak CM, Czerniecki BJ, Koski GK. Statin Drugs Plus Th1 Cytokines Potentiate Apoptosis and Ras Delocalization in Human Breast Cancer Lines and Combine with Dendritic Cell-Based Immunotherapy to Suppress Tumor Growth in a Mouse Model of HER-2 Disease. Vaccines. 8. PMID 32041347 DOI: 10.3390/vaccines8010072   
2020 Klejborowska G, Urbaniak A, Maj E, Preto J, Moshari M, Wietrzyk J, Tuszynski JA, Chambers TC, Huczyński A. Synthesis, biological evaluation and molecular docking studies of new amides of 4-chlorothiocolchicine as anticancer agents. Bioorganic Chemistry. 97: 103664. PMID 32106039 DOI: 10.1016/j.bioorg.2020.103664   
2020 Yang Y, Xie T, Tian X, Han N, Liu X, Chen H, Qi J, Gao F, Li W, Wu Q, Huo S, Gu Y, Dai Z, Wang P, Lei H. Betulinic Acid-Nitrogen Heterocyclic Derivatives: Design, Synthesis, and Antitumor Evaluation . Molecules (Basel, Switzerland). 25. PMID 32093264 DOI: 10.3390/molecules25040948   
2020 Leong SW, Chia SL, Abas F, Yusoff K. Synthesis and in-vitro anti-cancer evaluations of multi-methoxylated asymmetrical diarylpentanoids as intrinsic apoptosis inducer against colorectal cancer. Bioorganic & Medicinal Chemistry Letters. 127065. PMID 32127259 DOI: 10.1016/j.bmcl.2020.127065   
2020 Ye YS, Wu M, Jiang NN, Lao YZ, Fu WW, Liu X, Yang XW, Zhang J, Xu HX, Xu G. Dearomatized Isoprenylated Acylphloroglucinol Derivatives with Potential Antitumor Activities from Hypericum henryi. Natural Products and Bioprospecting. PMID 32016770 DOI: 10.1007/s13659-019-00229-w   
2020 Ning X, Ren X, Xie X, Yan P, Wang D, Huang X. A caffeic acid phenethyl ester analog inhibits the proliferation of nasopharyngeal carcinoma cells via targeting epidermal growth factor receptor. Journal of Biochemical and Molecular Toxicology. e22491. PMID 32125059 DOI: 10.1002/jbt.22491   
2020 Lotsberg ML, Wnuk-Lipinska K, Terry S, Tan TZ, Lu N, Trachsel-Moncho L, Røsland GV, Siraji MI, Hellesøy M, Rayford A, Jacobsen K, Ditzel HJ, Vintermyr OK, Bivona TG, Minna J, et al. AXL targeting abrogates autophagic flux and induces immunogenic cell death in drug resistant cancer cells. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. PMID 32018052 DOI: 10.1016/j.jtho.2020.01.015   
2020 Ma L, Zong X. Metabolic Symbiosis in Chemoresistance: Refocusing the Role of Aerobic Glycolysis. Frontiers in Oncology. 10: 5. PMID 32038983 DOI: 10.3389/fonc.2020.00005   
2020 Naz I, Ramchandani S, Khan MR, Yang MH, Ahn KS. Anticancer Potential of Raddeanin A, a Natural Triterpenoid Isolated from . Molecules (Basel, Switzerland). 25. PMID 32106609 DOI: 10.3390/molecules25051035   
2020 Al Matarneh CM, Amarandi RM, Craciun AM, Mangalagiu II, Zbancioc G, Danac R. Design, Synthesis, Molecular Modelling and Anticancer Activities of New Fused Phenanthrolines. Molecules (Basel, Switzerland). 25. PMID 31991806 DOI: 10.3390/molecules25030527   
2020 Almahmoud S, Jin W, Geng L, Wang J, Wang X, Vennerstrom JL, Zhong HA. Ligand-based design of GLUT inhibitors as potential antitumor agents. Bioorganic & Medicinal Chemistry. 115395. PMID 32113844 DOI: 10.1016/j.bmc.2020.115395   
2020 Kochanek SJ, Close DA, Camarco DP, Johnston PA. Maximizing the Value of Cancer Drug Screening in Multicellular Tumor Spheroid Cultures: A Case Study in Five Head and Neck Squamous Cell Carcinoma Cell Lines. Slas Discovery : Advancing Life Sciences R & D. 2472555219896999. PMID 31983262 DOI: 10.1177/2472555219896999   
2020 Alshehri SO, Malatani RT, Bogari HA, Noor AO, Ibrahim AK, Elhady SS, Abdelhameed RFA. LAMA-1: A Cerebroside Isolated from the Deep-Sea-Derived Fungus . Metabolites. 10. PMID 32093136 DOI: 10.3390/metabo10020075   
2020 Kil YS, Risinger AL, Petersen CL, Liang H, Grkovic T, O'Keefe BR, Mooberry SL, Cichewicz RH. Using the Cancer Dependency Map to Identify the Mechanism of Action of a Cytotoxic Alkenyl Derivative from the Fruit of . Journal of Natural Products. PMID 32105068 DOI: 10.1021/acs.jnatprod.9b00896   
2020 Leutcha BP, Sema DK, Dzoyem JP, Ayimele GA, Nyongbela KD, Delie F, Alléman É, Sewald N, Meli Lannang A. Cytotoxicity of a new tirucallane derivative isolated from K. Schum stem bark. Natural Product Research. 1-6. PMID 32011174 DOI: 10.1080/14786419.2020.1723085   
2020 Xing Y, Jiang Z, Akakuru OU, He Y, Li A, Li J, Wu A. Mitochondria-targeting zeolitic imidazole frameworks to overcome platinum-resistant ovarian cancer. Colloids and Surfaces. B, Biointerfaces. 189: 110837. PMID 32058250 DOI: 10.1016/j.colsurfb.2020.110837   
2020 Saraiva N, Costa JG, Reis C, Almeida N, Rijo P, Fernandes AS. Anti-Migratory and Pro-Apoptotic Properties of Parvifloron D on Triple-Negative Breast Cancer Cells. Biomolecules. 10. PMID 31963771 DOI: 10.3390/biom10010158   
2020 Huang Z, Wu Y, Allen ME, Pan Y, Kyriakakis P, Lu S, Chang YJ, Wang X, Chien S, Wang Y. Engineering light-controllable CAR T cells for cancer immunotherapy. Science Advances. 6: eaay9209. PMID 32128416 DOI: 10.1126/sciadv.aay9209   
2020 Wang Y, Chen X, Yan Y, Zhu X, Liu M, Liu X. Discovery and SARs of 5-chloro-N4-phenyl-N2-(pyridin-2-yl)pyrimidine-2,4-diamine derivatives as oral available and dual CDK 6 and 9 inhibitors with potent anti-tumor activity. Journal of Medicinal Chemistry. PMID 32129996 DOI: 10.1021/acs.jmedchem.9b02121   
2020 Luo X, Han G, Lu R, Guan S, Wang Y, Ju L, Chen L, Shao J, Bian Z. Transmembrane protein 106C promotes the development of hepatocellular carcinoma. Journal of Cellular Biochemistry. PMID 32037603 DOI: 10.1002/jcb.29678   
2020 Cheng J, Zhao W, Yao H, Shen Y, Zhang Y, Li YZ, Qi Q, Wongprasert K, Tang YJ. Discover 4,6-O-thenylidene-β-D-glucopyranoside-(2″-acetamido, 3″-acetyl-di-S-5-fluorobenzothizole/5-fluorobenzoxazole)-4'-demethylepipodophyllotoxin as potential less toxic antitumor candidate drugs by reducing DNA damage and less inhibition of PI3K. Journal of Medicinal Chemistry. PMID 32084316 DOI: 10.1021/acs.jmedchem.9b01354   
2020 Islam MS, Jahangir CA, Rahi MS, Hasan MM, Sajib SA, Hoque KMF, Reza MA. In-vivo antiproliferative activity of leaf and bark extracts against Ehrlich's ascites carcinoma. Toxicological Research. 36: 79-88. PMID 31998627 DOI: 10.1007/s43188-019-00011-7