| Year |
Citation |
Score |
| 2021 |
Najmi A, Wang S, Huang Y, Seefeldt T, Alqahtani Y, Guan X. 2-(2-Cholesteroxyethoxyl)ethyl 3'-S-glutathionylpropionate and Its Self-assembled Micelles for Brain Delivery: Design, Synthesis and Evaluation. International Journal of Pharmaceutics. 120520. PMID 33775725 DOI: 10.1016/j.ijpharm.2021.120520 |
0.67 |
|
| 2019 |
Alqahtani Y, Wang S, Huang Y, Najmi A, Guan X. Design, Synthesis, and Characterization of Bis(7-(N-(2-morpholinoethyl)sulfamoyl)benzo[c][1,2,5]oxadiazol-5-yl)sulfane (BISMORX) for Non-Protein Thiol Imaging in Lysosomes in Live Cells. Analytical Chemistry. PMID 31660721 DOI: 10.1021/Acs.Analchem.9B04552 |
0.362 |
|
| 2019 |
Alqahtani Y, Wang S, Najmi A, Huang Y, Guan X. Thiol-specific fluorogenic agent for live cell non-protein thiol imaging in lysosomes. Analytical and Bioanalytical Chemistry. PMID 31448387 DOI: 10.1007/S00216-019-02026-3 |
0.361 |
|
| 2018 |
Wang S, Yin H, Huang Y, Guan X. A Thiol Specific and Mitochondria Selective Fluorogenic Benzofurazan Sulfide for Live Cell Non-protein Thiol Imaging and Quantification in Mitochondria. Analytical Chemistry. PMID 29842788 DOI: 10.1021/Acs.Analchem.8B01469 |
0.329 |
|
| 2017 |
Sadhu SS, Wang S, Dachineni R, Averineni RK, Seefeldt T, Xie J, Tummala H, Bhat GJ, Guan X. In Vitro and In Vivo Antimetastatic Effect of Glutathione Disulfide Liposomes. Cancer Growth and Metastasis. 10: 1179064417695255. PMID 28469471 DOI: 10.1177/1179064417695255 |
0.718 |
|
| 2017 |
Yang Y, Guan X. Non-protein thiol imaging and quantification in live cells with a novel benzofurazan sulfide triphenylphosphonium fluorogenic compound. Analytical and Bioanalytical Chemistry. PMID 28357485 DOI: 10.1007/S00216-017-0285-Y |
0.353 |
|
| 2016 |
Sadhu SS, Xie J, Zhang H, Perumal O, Guan X. Glutathione Disulfide Liposomes - a Research Tool for the Study of Glutathione Disulfide Associated Functions and Dysfunctions. Biochemistry and Biophysics Reports. 7: 225-229. PMID 28409182 DOI: 10.1016/J.Bbrep.2016.06.017 |
0.385 |
|
| 2016 |
Rodman SN, Spence JM, Ronnfeldt TJ, Zhu Y, Solst SR, O'Neill RA, Allen BG, Guan X, Spitz DR, Fath MA. Enhancement of Radiation Response in Breast Cancer Stem Cells by Inhibition of Thioredoxin- and Glutathione-Dependent Metabolism. Radiation Research. PMID 27643875 DOI: 10.1667/Rr14463.1 |
0.376 |
|
| 2016 |
Sadhu SS, Wang S, Averineni RK, Seefeldt T, Yang Y, Guan X. In-vitro and in-vivo inhibition of melanoma growth and metastasis by the drug combination of celecoxib and dacarbazine. Melanoma Research. PMID 27540834 DOI: 10.1097/Cmr.0000000000000291 |
0.71 |
|
| 2015 |
Guan X. Cancer metastases: challenges and opportunities. Acta Pharmaceutica Sinica. B. 5: 402-418. PMID 26579471 DOI: 10.1016/J.Apsb.2015.07.005 |
0.352 |
|
| 2015 |
Chen W, Jiang Z, Lin N, Zheng Z, Chen Z, Zhang X, Guan X. Evaluation of N-acetyl-S-(p-chlorophenylcarbamoyl)cysteine as an irreversible inhibitor of mammalian thioredoxin reductase1. Journal of Enzyme Inhibition and Medicinal Chemistry. 1-7. PMID 25778746 DOI: 10.3109/14756366.2015.1016512 |
0.408 |
|
| 2015 |
Yang Y, Guan X. Rapid and thiol-specific high-throughput assay for simultaneous relative quantification of total thiols, protein thiols, and nonprotein thiols in cells Analytical Chemistry. 87: 649-655. PMID 25423115 DOI: 10.1021/Ac503411P |
0.334 |
|
| 2013 |
Sadhu SS, Callegari E, Zhao Y, Guan X, Seefeldt T. Evaluation of a dithiocarbamate derivative as an inhibitor of human glutaredoxin-1. Journal of Enzyme Inhibition and Medicinal Chemistry. 28: 456-62. PMID 22299579 DOI: 10.3109/14756366.2011.649267 |
0.712 |
|
| 2012 |
Li Y, Yang Y, Guan X. Benzofurazan sulfides for thiol imaging and quantification in live cells through fluorescence microscopy. Analytical Chemistry. 84: 6877-83. PMID 22794193 DOI: 10.1021/Ac301306S |
0.303 |
|
| 2012 |
Chen W, Seefeldt T, Young A, Zhang X, Zhao Y, Ruffolo J, Kaushik RS, Guan X. Microtubule S-glutathionylation as a potential approach for antimitotic agents. Bmc Cancer. 12: 245. PMID 22703118 DOI: 10.1186/1471-2407-12-245 |
0.72 |
|
| 2011 |
Chen W, Seefeldt T, Young A, Zhang X, Guan X. Design, synthesis, and biological evaluation of N-acetyl-S-(p-chlorophenylcarbamoyl)cysteine and its analogs as a novel class of anticancer agents. Bioorganic & Medicinal Chemistry. 19: 287-94. PMID 21131205 DOI: 10.1016/J.Bmc.2010.11.026 |
0.738 |
|
| 2010 |
Chen Z, Lawson S, Sun Z, Zhou X, Guan X, Christopher-Hennings J, Nelson EA, Fang Y. Identification of two auto-cleavage products of nonstructural protein 1 (nsp1) in porcine reproductive and respiratory syndrome virus infected cells: nsp1 function as interferon antagonist. Virology. 398: 87-97. PMID 20006994 DOI: 10.1016/J.Virol.2009.11.033 |
0.306 |
|
| 2010 |
Chen W, Seefeldt T, Young A, Zhang X, Ruffolo J, Kaushik R, Guan X. Abstract 4422: 2-AAPA: A novel anticancer agent that induces microtubule depolymerization and apoptosis Cancer Research. 70: 4422-4422. DOI: 10.1158/1538-7445.Am10-4422 |
0.736 |
|
| 2009 |
Zhao Y, Seefeldt T, Chen W, Carlson L, Stoebner A, Hanson S, Foll R, Matthees DP, Palakurthi S, Guan X. Increase in thiol oxidative stress via glutathione reductase inhibition as a novel approach to enhance cancer sensitivity to X-ray irradiation. Free Radical Biology & Medicine. 47: 176-83. PMID 19397999 DOI: 10.1016/J.Freeradbiomed.2009.04.022 |
0.706 |
|
| 2009 |
Zhao Y, Seefeldt T, Chen W, Wang X, Matthees D, Hu Y, Guan X. Effects of glutathione reductase inhibition on cellular thiol redox state and related systems. Archives of Biochemistry and Biophysics. 485: 56-62. PMID 19272349 DOI: 10.1016/J.Abb.2009.03.001 |
0.725 |
|
| 2009 |
Seefeldt T, Zhao Y, Chen W, Raza AS, Carlson L, Herman J, Stoebner A, Hanson S, Foll R, Guan X. Characterization of a novel dithiocarbamate glutathione reductase inhibitor and its use as a tool to modulate intracellular glutathione. The Journal of Biological Chemistry. 284: 2729-37. PMID 19049979 DOI: 10.1074/Jbc.M802683200 |
0.741 |
|
| 2008 |
Chen W, Zhao Y, Seefeldt T, Guan X. Determination of thiols and disulfides via HPLC quantification of 5-thio-2-nitrobenzoic acid. Journal of Pharmaceutical and Biomedical Analysis. 48: 1375-80. PMID 18926658 DOI: 10.1016/J.Jpba.2008.08.033 |
0.703 |
|
| 2008 |
Pisal DS, Yellepeddi VK, Kumar A, Kaushik RS, Hildreth MB, Guan X, Palakurthi S. Permeability of surface-modified polyamidoamine (PAMAM) dendrimers across Caco-2 cell monolayers. International Journal of Pharmaceutics. 350: 113-21. PMID 17913410 DOI: 10.1016/J.Ijpharm.2007.08.033 |
0.354 |
|
| 2005 |
Seefeldt T, Dwivedi C, Peitz G, Herman J, Carlson L, Zhang Z, Guan X. 2-Acetylamino-3-[4-(2-acetylamino-2-carboxyethylsulfanylcarbonylamino)- phenylcarbamoylsulfanyl]propionic acid and its derivatives as a novel class of glutathione reductase inhibitors. Journal of Medicinal Chemistry. 48: 5224-31. PMID 16078841 DOI: 10.1021/Jm050030I |
0.732 |
|
| 2005 |
Kaur M, Agarwal C, Singh RP, Guan X, Dwivedi C, Agarwal R. Skin cancer chemopreventive agent, {alpha}-santalol, induces apoptotic death of human epidermoid carcinoma A431 cells via caspase activation together with dissipation of mitochondrial membrane potential and cytochrome c release. Carcinogenesis. 26: 369-80. PMID 15528219 DOI: 10.1093/Carcin/Bgh325 |
0.342 |
|
| 2002 |
Guan X, Hoffman BN, McFarland DC, Gilkerson KK, Dwivedi C, Erickson AK, Bebensee S, Pellegrini J. Glutathione and mercapturic acid conjugates of sulofenur and their activity against a human colon cancer cell line. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 30: 331-5. PMID 11854154 DOI: 10.1124/Dmd.30.3.331 |
0.408 |
|
| 1999 |
Guan X, Davis MR, Tang C, Jochheim CM, Jin L, Baillie TA. Identification of S-(n-butylcarbamoyl)glutathione, a reactive carbamoylating metabolite of tolbutamide in the rat, and evaluation of its inhibitory effects on glutathione reductase in vitro. Chemical Research in Toxicology. 12: 1138-43. PMID 10604861 DOI: 10.1021/Tx990086D |
0.378 |
|
| 1998 |
Guan X, Fisher MB, Lang DH, Zheng YM, Koop DR, Rettie AE. Cytochrome P450-dependent desaturation of lauric acid: isoform selectivity and mechanism of formation of 11-dodecenoic acid. Chemico-Biological Interactions. 110: 103-21. PMID 9566728 DOI: 10.1016/S0009-2797(97)00145-2 |
0.31 |
|
| 1994 |
Guan X, Davis MR, Jin L, Baillie TA. Identification of S-(n-butylcarbamoyl)glutathione, a reactive carbamoylating agent, as a biliary metabolite of benomyl in the rat Journal of Agricultural and Food Chemistry. 42: 2953-2957. DOI: 10.1021/Jf00048A058 |
0.333 |
|
| 1991 |
Georg GI, Guan X, Kant J. Asymmetric synthesis of α-alkylated α-amino acids: azepane-2-carboxylic acids Bioorganic and Medicinal Chemistry Letters. 1: 125-128. DOI: 10.1016/S0960-894X(00)80245-0 |
0.471 |
|
| 1991 |
Georg GI, Mashava PM, Guan X. An improved method for the stereoselective synthesis of β-lactams from carboxylic acids and imines Tetrahedron Letters. 32: 581-584. DOI: 10.1016/S0040-4039(00)74832-5 |
0.483 |
|
| 1988 |
Georg GI, Guan X, Kant J. Asymmetric synthesis of α-alkylated α-amino acids via Schmidt rearrangement of α, α-bisalkylated β-keto esters Tetrahedron Letters. 29: 403-406. DOI: 10.1016/S0040-4039(00)80107-0 |
0.442 |
|
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