Alan D. D'Andrea - Publications

Biology: Medical Sciences, Division of Harvard University, Cambridge, MA, United States 
Molecular Biology, Biochemistry, Bioinformatics Biology

122 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Clairmont CS, Sarangi P, Ponnienselvan K, Galli LD, Csete I, Moreau L, Adelmant G, Chowdhury D, Marto JA, D'Andrea AD. TRIP13 regulates DNA repair pathway choice through REV7 conformational change. Nature Cell Biology. 22: 87-96. PMID 31915374 DOI: 10.1038/s41556-019-0442-y  0.32
2018 Przetocka S, Porro A, Bolck HA, Walker C, Lezaja A, Trenner A, von Aesch C, Himmels SF, D'Andrea AD, Ceccaldi R, Altmeyer M, Sartori AA. CtIP-Mediated Fork Protection Synergizes with BRCA1 to Suppress Genomic Instability upon DNA Replication Stress. Molecular Cell. PMID 30344097 DOI: 10.1016/j.molcel.2018.09.014  0.32
2017 Rondinelli B, Gogola E, Yücel H, Duarte AA, van de Ven M, van der Sluijs R, Konstantinopoulos PA, Jonkers J, Ceccaldi R, Rottenberg S, D'Andrea AD. EZH2 promotes degradation of stalled replication forks by recruiting MUS81 through histone H3 trimethylation. Nature Cell Biology. PMID 29035360 DOI: 10.1038/ncb3626  0.32
2017 Bluteau D, Masliah-Planchon J, Clairmont C, Rousseau A, Ceccaldi R, d'Enghien CD, Bluteau O, Cuccuini W, Gachet S, de Latour RP, Leblanc T, Socié G, Baruchel A, Stoppa-Lyonnet D, D'Andrea AD, et al. Biallelic inactivation of REV7 is associated with Fanconi anemia. The Journal of Clinical Investigation. 127: 1117. PMID 28248207 DOI: 10.1172/JCI92946  0.32
2016 Jo U, Cai W, Wang J, Kwon Y, D'Andrea AD, Kim H. PCNA-Dependent Cleavage and Degradation of SDE2 Regulates Response to Replication Stress. Plos Genetics. 12: e1006465. PMID 27906959 DOI: 10.1371/journal.pgen.1006465  0.56
2016 Bluteau D, Masliah-Planchon J, Clairmont C, Rousseau A, Ceccaldi R, Dubois d'Enghien C, Bluteau O, Cuccuini W, Gachet S, Peffault de Latour R, Leblanc T, Socié G, Baruchel A, Stoppa-Lyonnet D, D'Andrea AD, et al. Biallelic inactivation of REV7 is associated with Fanconi anemia. The Journal of Clinical Investigation. PMID 27500492 DOI: 10.1172/JCI88010  0.32
2016 Li H, Lim KS, Kim H, Hinds TR, Jo U, Mao H, Weller CE, Sun J, Chatterjee C, D'Andrea AD, Zheng N. Allosteric Activation of Ubiquitin-Specific Proteases by β-Propeller Proteins UAF1 and WDR20. Molecular Cell. PMID 27373336 DOI: 10.1016/j.molcel.2016.05.031  0.56
2016 Kais Z, Rondinelli B, Holmes A, O'Leary C, Kozono D, D'Andrea AD, Ceccaldi R. FANCD2 Maintains Fork Stability in BRCA1/2-Deficient Tumors and Promotes Alternative End-Joining DNA Repair. Cell Reports. PMID 27264184 DOI: 10.1016/j.celrep.2016.05.031  0.32
2016 Ceccaldi R, Sarangi P, D'Andrea AD. The Fanconi anaemia pathway: new players and new functions. Nature Reviews. Molecular Cell Biology. PMID 27145721 DOI: 10.1038/nrm.2016.48  0.32
2016 Dinh TK, Fendler W, Chałubińska-Fendler J, Acharya SS, O'Leary C, Deraska PV, D'Andrea AD, Chowdhury D, Kozono D. Circulating miR-29a and miR-150 correlate with delivered dose during thoracic radiation therapy for non-small cell lung cancer. Radiation Oncology (London, England). 11: 61. PMID 27117590 DOI: 10.1186/s13014-016-0636-4  1
2016 Zhang H, Kozono DE, O'Connor KW, Vidal-Cardenas S, Rousseau A, Hamilton A, Moreau L, Gaudiano EF, Greenberger J, Bagby G, Soulier J, Grompe M, Parmar K, D'Andrea AD. TGF-β Inhibition Rescues Hematopoietic Stem Cell Defects and Bone Marrow Failure in Fanconi Anemia. Cell Stem Cell. PMID 27053300 DOI: 10.1016/j.stem.2016.03.002  1
2016 Ceccaldi R, Rondinelli B, D'Andrea AD. Repair Pathway Choices and Consequences at the Double-Strand Break. Trends in Cell Biology. 26: 52-64. PMID 26437586 DOI: 10.1016/j.tcb.2015.07.009  0.32
2015 Xie J, Kim H, Moreau LA, Puhalla S, Garber J, Al Abo M, Takeda S, D'Andrea AD. RNF4-mediated polyubiquitination regulates the Fanconi anemia/BRCA pathway. The Journal of Clinical Investigation. 125: 1523-32. PMID 25751062 DOI: 10.1172/JCI79325  1
2015 Ceccaldi R, Liu JC, Amunugama R, Hajdu I, Primack B, Petalcorin MI, O'Connor KW, Konstantinopoulos PA, Elledge SJ, Boulton SJ, Yusufzai T, D'Andrea AD. Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair. Nature. 518: 258-62. PMID 25642963 DOI: 10.1038/nature14184  0.32
2015 Ceccaldi R, O'Connor KW, Mouw KW, Li AY, Matulonis UA, D'Andrea AD, Konstantinopoulos PA. A unique subset of epithelial ovarian cancers with platinum sensitivity and PARP inhibitor resistance. Cancer Research. 75: 628-34. PMID 25634215 DOI: 10.1158/0008-5472.CAN-14-2593  1
2015 Ceccaldi R, Liu JC, Amunugama R, Hajdu I, Primack B, Petalcorin MIR, O'Connor KW, Konstantinopoulos PA, Elledge SJ, Boulton SJ, Yusufzai T, D'Andrea AD. Homologous-recombination-deficient tumours are dependent on Polθ -mediated repair Nature. 518: 258-262. DOI: 10.1038/nature14184  1
2014 Wojtaszek JL, Wang S, Kim H, Wu Q, D'Andrea AD, Zhou P. Ubiquitin recognition by FAAP20 expands the complex interface beyond the canonical UBZ domain. Nucleic Acids Research. 42: 13997-4005. PMID 25414354 DOI: 10.1093/nar/gku1153  0.56
2014 Mouw KW, D'Andrea AD. Crosstalk between the nucleotide excision repair and Fanconi anemia/BRCA pathways. Dna Repair. 19: 130-4. PMID 24768451 DOI: 10.1016/j.dnarep.2014.03.019  1
2014 Kim H, Dejsuphong D, Adelmant G, Ceccaldi R, Yang K, Marto JA, D'Andrea AD. Transcriptional repressor ZBTB1 promotes chromatin remodeling and translesion DNA synthesis. Molecular Cell. 54: 107-18. PMID 24657165 DOI: 10.1016/j.molcel.2014.02.017  1
2014 Polito D, Cukras S, Wang X, Spence P, Moreau L, D'Andrea AD, Kee Y. The carboxyl terminus of FANCE recruits FANCD2 to the Fanconi Anemia (FA) E3 ligase complex to promote the FA DNA repair pathway. The Journal of Biological Chemistry. 289: 7003-10. PMID 24451376 DOI: 10.1074/jbc.M113.533976  1
2013 Etemadmoghadam D, Weir BA, Au-Yeung G, Alsop K, Mitchell G, George J, Davis S, D'Andrea AD, Simpson K, Hahn WC, Bowtell DD. Synthetic lethality between CCNE1 amplification and loss of BRCA1. Proceedings of the National Academy of Sciences of the United States of America. 110: 19489-94. PMID 24218601 DOI: 10.1073/pnas.1314302110  1
2013 Mistry H, Hsieh G, Buhrlage SJ, Huang M, Park E, Cuny GD, Galinsky I, Stone RM, Gray NS, D'Andrea AD, Parmar K. Small-molecule inhibitors of USP1 target ID1 degradation in leukemic cells. Molecular Cancer Therapeutics. 12: 2651-62. PMID 24130053 DOI: 10.1158/1535-7163.MCT-13-0103-T  1
2013 Johnson N, Johnson SF, Yao W, Li YC, Choi YE, Bernhardy AJ, Wang Y, Capelletti M, Sarosiek KA, Moreau LA, Chowdhury D, Wickramanayake A, Harrell MI, Liu JF, D'Andrea AD, et al. Stabilization of mutant BRCA1 protein confers PARP inhibitor and platinum resistance. Proceedings of the National Academy of Sciences of the United States of America. 110: 17041-6. PMID 24085845 DOI: 10.1073/pnas.1305170110  1
2013 Cron KR, Zhu K, Kushwaha DS, Hsieh G, Merzon D, Rameseder J, Chen CC, D'Andrea AD, Kozono D. Proteasome inhibitors block DNA repair and radiosensitize non-small cell lung cancer. Plos One. 8: e73710. PMID 24040035 DOI: 10.1371/journal.pone.0073710  1
2013 Park E, Kim JM, Primack B, Weinstock DM, Moreau LA, Parmar K, D'Andrea AD. Inactivation of Uaf1 causes defective homologous recombination and early embryonic lethality in mice. Molecular and Cellular Biology. 33: 4360-70. PMID 24001775 DOI: 10.1128/MCB.00870-13  1
2013 Park E, Kim H, Kim JM, Primack B, Vidal-Cardenas S, Xu Y, Price BD, Mills AA, D'Andrea AD. FANCD2 activates transcription of TAp63 and suppresses tumorigenesis. Molecular Cell. 50: 908-18. PMID 23806336 DOI: 10.1016/j.molcel.2013.05.017  1
2013 Price BD, D'Andrea AD. Chromatin remodeling at DNA double-strand breaks. Cell. 152: 1344-54. PMID 23498941 DOI: 10.1016/j.cell.2013.02.011  1
2013 O'Connor KW, Dejsuphong D, Park E, Nicolae CM, Kimmelman AC, D'Andrea AD, Moldovan GL. PARI overexpression promotes genomic instability and pancreatic tumorigenesis. Cancer Research. 73: 2529-39. PMID 23436799 DOI: 10.1158/0008-5472.CAN-12-3313  1
2012 Wojtaszek J, Lee CJ, D'Souza S, Minesinger B, Kim H, D'Andrea AD, Walker GC, Zhou P. Structural basis of Rev1-mediated assembly of a quaternary vertebrate translesion polymerase complex consisting of Rev1, heterodimeric polymerase (Pol) ζ, and Pol κ. The Journal of Biological Chemistry. 287: 33836-46. PMID 22859295 DOI: 10.1074/jbc.M112.394841  1
2012 Moldovan GL, D'Andrea AD. To the rescue: the Fanconi anemia genome stability pathway salvages replication forks. Cancer Cell. 22: 5-6. PMID 22789533 DOI: 10.1016/j.ccr.2012.06.006  0.56
2012 Kim H, D'Andrea AD. Regulation of DNA cross-link repair by the Fanconi anemia/BRCA pathway. Genes & Development. 26: 1393-408. PMID 22751496 DOI: 10.1101/gad.195248.112  0.56
2012 Ceccaldi R, Parmar K, Mouly E, Delord M, Kim JM, Regairaz M, Pla M, Vasquez N, Zhang QS, Pondarre C, Peffault de Latour R, Gluckman E, Cavazzana-Calvo M, Leblanc T, Larghero J, et al. Bone marrow failure in Fanconi anemia is triggered by an exacerbated p53/p21 DNA damage response that impairs hematopoietic stem and progenitor cells. Cell Stem Cell. 11: 36-49. PMID 22683204 DOI: 10.1016/j.stem.2012.05.013  1
2012 Bunting SF, Callén E, Kozak ML, Kim JM, Wong N, López-Contreras AJ, Ludwig T, Baer R, Faryabi RB, Malhowski A, Chen HT, Fernandez-Capetillo O, D'Andrea A, Nussenzweig A. BRCA1 functions independently of homologous recombination in DNA interstrand crosslink repair. Molecular Cell. 46: 125-35. PMID 22445484 DOI: 10.1016/j.molcel.2012.02.015  1
2012 Kim H, Yang K, Dejsuphong D, D'Andrea AD. Regulation of Rev1 by the Fanconi anemia core complex. Nature Structural & Molecular Biology. 19: 164-70. PMID 22266823 DOI: 10.1038/nsmb.2222  0.56
2012 Kee Y, Huang M, Chang S, Moreau LA, Park E, Smith PG, D'Andrea AD. Inhibition of the Nedd8 system sensitizes cells to DNA interstrand cross-linking agents. Molecular Cancer Research : McR. 10: 369-77. PMID 22219386 DOI: 10.1158/1541-7786.MCR-11-0497  1
2012 Moldovan GL, Dejsuphong D, Petalcorin MI, Hofmann K, Takeda S, Boulton SJ, D'Andrea AD. Inhibition of homologous recombination by the PCNA-interacting protein PARI. Molecular Cell. 45: 75-86. PMID 22153967 DOI: 10.1016/j.molcel.2011.11.010  0.56
2011 Guinan EC, Barbon CM, Kalish LA, Parmar K, Kutok J, Mancuso CJ, Stoler-Barak L, Suter EE, Russell JD, Palmer CD, Gallington LC, Voskertchian A, Vergilio JA, Cole G, Zhu K, et al. Bactericidal/permeability-increasing protein (rBPI21) and fluoroquinolone mitigate radiation-induced bone marrow aplasia and death. Science Translational Medicine. 3: 110ra118. PMID 22116933 DOI: 10.1126/scitranslmed.3003126  1
2011 Ayrapetov MK, Xu C, Sun Y, Zhu K, Parmar K, D'Andrea AD, Price BD. Activation of Hif1α by the prolylhydroxylase inhibitor dimethyoxalyglycine decreases radiosensitivity. Plos One. 6: e26064. PMID 22016813 DOI: 10.1371/journal.pone.0026064  1
2011 Huang M, Kennedy R, Ali AM, Moreau LA, Meetei AR, D'Andrea AD, Chen CC. Human MutS and FANCM complexes function as redundant DNA damage sensors in the Fanconi Anemia pathway. Dna Repair. 10: 1203-12. PMID 21975120 DOI: 10.1016/j.dnarep.2011.09.006  1
2011 Hendel A, Krijger PH, Diamant N, Goren Z, Langerak P, Kim J, Reissner T, Lee KY, Geacintov NE, Carell T, Myung K, Tateishi S, D'Andrea A, Jacobs H, Livneh Z. PCNA ubiquitination is important, but not essential for translesion DNA synthesis in mammalian cells. Plos Genetics. 7: e1002262. PMID 21931560 DOI: 10.1371/journal.pgen.1002262  1
2011 Yang K, Moldovan GL, Vinciguerra P, Murai J, Takeda S, D'Andrea AD. Regulation of the Fanconi anemia pathway by a SUMO-like delivery network. Genes & Development. 25: 1847-58. PMID 21896657 DOI: 10.1101/gad.17020911  0.56
2011 Vaezi A, Wang X, Buch S, Gooding W, Wang L, Seethala RR, Weaver DT, D'Andrea AD, Argiris A, Romkes M, Niedernhofer LJ, Grandis JR. XPF expression correlates with clinical outcome in squamous cell carcinoma of the head and neck. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 5513-22. PMID 21737503 DOI: 10.1158/1078-0432.CCR-11-0086  1
2011 Johnson N, Li YC, Walton ZE, Cheng KA, Li D, Rodig SJ, Moreau LA, Unitt C, Bronson RT, Thomas HD, Newell DR, D'Andrea AD, Curtin NJ, Wong KK, Shapiro GI. Compromised CDK1 activity sensitizes BRCA-proficient cancers to PARP inhibition. Nature Medicine. 17: 875-82. PMID 21706030 DOI: 10.1038/nm.2377  1
2011 Kao WH, Riker AI, Kushwaha DS, Ng K, Enkemann SA, Jove R, Buettner R, Zinn PO, Sánchez NP, Villa JL, D'Andrea AD, Sánchez JL, Kennedy RD, Chen CC, Matta JL. Upregulation of Fanconi anemia DNA repair genes in melanoma compared with non-melanoma skin cancer. The Journal of Investigative Dermatology. 131: 2139-42. PMID 21697891 DOI: 10.1038/jid.2011.181  1
2011 Moldovan GL, D'Andrea AD. DNA damage discrimination at stalled replication forks by the Rad5 homologs HLTF and SHPRH. Molecular Cell. 42: 141-3. PMID 21504827 DOI: 10.1016/j.molcel.2011.03.018  0.56
2011 Murai J, Yang K, Dejsuphong D, Hirota K, Takeda S, D'Andrea AD. The USP1/UAF1 complex promotes double-strand break repair through homologous recombination. Molecular and Cellular Biology. 31: 2462-9. PMID 21482670 DOI: 10.1128/MCB.05058-11  0.56
2010 Alexander BM, Sprott K, Farrow DA, Wang X, D'Andrea AD, Schnitt SJ, Collins LC, Weaver DT, Garber JE. DNA repair protein biomarkers associated with time to recurrence in triple-negative breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 5796-804. PMID 21138871 DOI: 10.1158/1078-0432.CCR-10-0292  1
2010 Vinciguerra P, Godinho SA, Parmar K, Pellman D, D'Andrea AD. Cytokinesis failure occurs in Fanconi anemia pathway-deficient murine and human bone marrow hematopoietic cells. The Journal of Clinical Investigation. 120: 3834-42. PMID 20921626 DOI: 10.1172/JCI43391  1
2010 Huang M, Kim JM, Shiotani B, Yang K, Zou L, D'Andrea AD. The FANCM/FAAP24 complex is required for the DNA interstrand crosslink-induced checkpoint response. Molecular Cell. 39: 259-68. PMID 20670894 DOI: 10.1016/j.molcel.2010.07.005  0.56
2010 Nitta M, Kozono D, Kennedy R, Stommel J, Ng K, Zinn PO, Kushwaha D, Kesari S, Inda MM, Wykosky J, Furnari F, Hoadley KA, Chin L, DePinho RA, Cavenee WK, et al. Targeting EGFR induced oxidative stress by PARP1 inhibition in glioblastoma therapy. Plos One. 5: e10767. PMID 20532243 DOI: 10.1371/journal.pone.0010767  1
2010 Yang K, Moldovan GL, D'Andrea AD. RAD18-dependent recruitment of SNM1A to DNA repair complexes by a ubiquitin-binding zinc finger. The Journal of Biological Chemistry. 285: 19085-91. PMID 20385554 DOI: 10.1074/jbc.M109.100032  0.56
2010 Kee Y, Yang K, Cohn MA, Haas W, Gygi SP, D'Andrea AD. WDR20 regulates activity of the USP12 x UAF1 deubiquitinating enzyme complex. The Journal of Biological Chemistry. 285: 11252-7. PMID 20147737 DOI: 10.1074/jbc.M109.095141  1
2010 Lee KY, Yang K, Cohn MA, Sikdar N, D'Andrea AD, Myung K. Human ELG1 regulates the level of ubiquitinated proliferating cell nuclear antigen (PCNA) through Its interactions with PCNA and USP1. The Journal of Biological Chemistry. 285: 10362-9. PMID 20147293 DOI: 10.1074/jbc.M109.092544  1
2010 Moldovan GL, Madhavan MV, Mirchandani KD, McCaffrey RM, Vinciguerra P, D'Andrea AD. DNA polymerase POLN participates in cross-link repair and homologous recombination. Molecular and Cellular Biology. 30: 1088-96. PMID 19995904 DOI: 10.1128/MCB.01124-09  1
2009 Vinciguerra P, D'Andrea AD. FANCM: A landing pad for the Fanconi Anemia and Bloom's Syndrome complexes. Molecular Cell. 36: 916-7. PMID 20064455 DOI: 10.1016/j.molcel.2009.12.007  0.36
2009 Moldovan GL, D'Andrea AD. FANCD2 hurdles the DNA interstrand crosslink. Cell. 139: 1222-4. PMID 20064367 DOI: 10.1016/j.cell.2009.12.006  0.56
2009 Bhagwat N, Olsen AL, Wang AT, Hanada K, Stuckert P, Kanaar R, D'Andrea A, Niedernhofer LJ, McHugh PJ. XPF-ERCC1 participates in the Fanconi anemia pathway of cross-link repair. Molecular and Cellular Biology. 29: 6427-37. PMID 19805513 DOI: 10.1128/MCB.00086-09  1
2009 Moldovan GL, D'Andrea AD. How the fanconi anemia pathway guards the genome. Annual Review of Genetics. 43: 223-49. PMID 19686080 DOI: 10.1146/annurev-genet-102108-134222  0.56
2009 Johnson N, Cai D, Kennedy RD, Pathania S, Arora M, Li YC, D'Andrea AD, Parvin JD, Shapiro GI. Cdk1 participates in BRCA1-dependent S phase checkpoint control in response to DNA damage. Molecular Cell. 35: 327-39. PMID 19683496 DOI: 10.1016/j.molcel.2009.06.036  1
2009 Chen CC, Kennedy RD, Sidi S, Look AT, D'Andrea A. CHK1 inhibition as a strategy for targeting Fanconi Anemia (FA) DNA repair pathway deficient tumors. Molecular Cancer. 8: 24. PMID 19371427 DOI: 10.1186/1476-4598-8-24  1
2009 Kim JM, Parmar K, Huang M, Weinstock DM, Ruit CA, Kutok JL, D'Andrea AD. Inactivation of murine Usp1 results in genomic instability and a Fanconi anemia phenotype. Developmental Cell. 16: 314-20. PMID 19217432 DOI: 10.1016/j.devcel.2009.01.001  1
2009 Cohn MA, Kee Y, Haas W, Gygi SP, D'Andrea AD. UAF1 is a subunit of multiple deubiquitinating enzyme complexes. The Journal of Biological Chemistry. 284: 5343-51. PMID 19075014 DOI: 10.1074/jbc.M808430200  1
2008 Cohn MA, D'Andrea AD. Chromatin recruitment of DNA repair proteins: lessons from the fanconi anemia and double-strand break repair pathways. Molecular Cell. 32: 306-12. PMID 18995829 DOI: 10.1016/j.molcel.2008.10.009  1
2008 Mirchandani KD, McCaffrey RM, D'Andrea AD. The Fanconi anemia core complex is required for efficient point mutagenesis and Rev1 foci assembly. Dna Repair. 7: 902-11. PMID 18448394 DOI: 10.1016/j.dnarep.2008.03.001  1
2007 Cohn MA, Kowal P, Yang K, Haas W, Huang TT, Gygi SP, D'Andrea AD. A UAF1-containing multisubunit protein complex regulates the Fanconi anemia pathway. Molecular Cell. 28: 786-97. PMID 18082604 DOI: 10.1016/j.molcel.2007.09.031  1
2007 Kennedy RD, Chen CC, Stuckert P, Archila EM, De la Vega MA, Moreau LA, Shimamura A, D'Andrea AD. Fanconi anemia pathway-deficient tumor cells are hypersensitive to inhibition of ataxia telangiectasia mutated. The Journal of Clinical Investigation. 117: 1440-9. PMID 17431503 DOI: 10.1172/JCI31245  1
2007 Smogorzewska A, Matsuoka S, Vinciguerra P, McDonald ER, Hurov KE, Luo J, Ballif BA, Gygi SP, Hofmann K, D'Andrea AD, Elledge SJ. Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair. Cell. 129: 289-301. PMID 17412408 DOI: 10.1016/j.cell.2007.03.009  1
2007 Wang X, Kennedy RD, Ray K, Stuckert P, Ellenberger T, D'Andrea AD. Chk1-mediated phosphorylation of FANCE is required for the Fanconi anemia/BRCA pathway Molecular and Cellular Biology. 27: 3098-3108. PMID 17296736 DOI: 10.1128/MCB.02357-06  1
2007 Chen CC, Taniguchi T, D'Andrea A. The Fanconi anemia (FA) pathway confers glioma resistance to DNA alkylating agents Journal of Molecular Medicine. 85: 497-509. PMID 17221219 DOI: 10.1007/s00109-006-0153-2  1
2007 Kowal P, Gurtan AM, Stuckert P, D'Andrea AD, Ellenberger T. Structural determinants of human FANCF protein that function in the assembly of a DNA damage signaling complex Journal of Biological Chemistry. 282: 2047-2055. PMID 17082180 DOI: 10.1074/jbc.M608356200  1
2006 Huang TT, D'Andrea AD. HAUSP hunting the FOX(O) Nature Cell Biology. 8: 1043-1045. PMID 17013413 DOI: 10.1038/ncb1006-1043  1
2006 Machida YJ, Machida Y, Chen Y, Gurtan AM, Kupfer GM, D'Andrea AD, Dutta A. UBE2T is the E2 in the Fanconi anemia pathway and undergoes negative autoregulation. Molecular Cell. 23: 589-96. PMID 16916645 DOI: 10.1016/j.molcel.2006.06.024  0.88
2006 Kennedy RD, D'Andrea AD. DNA repair pathways in clinical practice: lessons from pediatric cancer susceptibility syndromes. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 24: 3799-808. PMID 16896009 DOI: 10.1200/JCO.2005.05.4171  1
2006 Mirchandani KD, D'Andrea AD. The Fanconi anemia/BRCA pathway: a coordinator of cross-link repair. Experimental Cell Research. 312: 2647-53. PMID 16859679 DOI: 10.1016/j.yexcr.2006.06.014  1
2006 Gurtan AM, D'Andrea AD. Dedicated to the core: understanding the Fanconi anemia complex. Dna Repair. 5: 1119-25. PMID 16784902 DOI: 10.1016/j.dnarep.2006.05.009  0.88
2006 Chirnomas D, Taniguchi T, de la Vega M, Vaidya AP, Vasserman M, Hartman AR, Kennedy R, Foster R, Mahoney J, Seiden MV, D'Andrea AD. Chemosensitization to cisplatin by inhibitors of the Fanconi anemia/BRCA pathway. Molecular Cancer Therapeutics. 5: 952-61. PMID 16648566 DOI: 10.1158/1535-7163.MCT-05-0493  1
2006 Huang TT, D'Andrea AD. Regulation of DNA repair by ubiquitylation. Nature Reviews. Molecular Cell Biology. 7: 323-34. PMID 16633336 DOI: 10.1038/nrm1908  1
2006 Huang TT, Nijman SM, Mirchandani KD, Galardy PJ, Cohn MA, Haas W, Gygi SP, Ploegh HL, Bernards R, D'Andrea AD. Regulation of monoubiquitinated PCNA by DUB autocleavage. Nature Cell Biology. 8: 339-47. PMID 16531995 DOI: 10.1038/ncb1378  1
2006 Andreassen PR, Ho GP, D'Andrea AD. DNA damage responses and their many interactions with the replication fork. Carcinogenesis. 27: 883-92. PMID 16490739 DOI: 10.1093/carcin/bgi319  0.52
2006 Gurtan AM, Stuckert P, D'Andrea AD. The WD40 repeats of FANCL are required for Fanconi anemia core complex assembly. The Journal of Biological Chemistry. 281: 10896-905. PMID 16474167 DOI: 10.1074/jbc.M511411200  0.88
2006 Howlett NG, Scuric Z, D'Andrea AD, Schiestl RH. Impaired DNA double strand break repair in cells from Nijmegen breakage syndrome patients. Dna Repair. 5: 251-7. PMID 16309973 DOI: 10.1016/j.dnarep.2005.10.004  1
2005 Kennedy RD, D'Andrea AD. The Fanconi Anemia/BRCA pathway: new faces in the crowd. Genes & Development. 19: 2925-40. PMID 16357213 DOI: 10.1101/gad.1370505  1
2005 Levine RL, Wadleigh M, Cools J, Ebert BL, Wernig G, Huntly BJ, Boggon TJ, Wlodarska I, Clark JJ, Moore S, Adelsperger J, Koo S, Lee JC, Gabriel S, Mercher T, et al. Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis. Cancer Cell. 7: 387-97. PMID 15837627 DOI: 10.1016/j.ccr.2005.03.023  1
2005 Howlett NG, Taniguchi T, Durkin SG, D'Andrea AD, Glover TW. The Fanconi anemia pathway is required for the DNA replication stress response and for the regulation of common fragile site stability. Human Molecular Genetics. 14: 693-701. PMID 15661754 DOI: 10.1093/hmg/ddi065  1
2005 Montes de Oca R, Andreassen PR, Margossian SP, Gregory RC, Taniguchi T, Wang X, Houghtaling S, Grompe M, D'Andrea AD. Regulated interaction of the Fanconi anemia protein, FANCD2, with chromatin. Blood. 105: 1003-9. PMID 15454491 DOI: 10.1182/blood-2003-11-3997  1
2005 Soulier J, Leblanc T, Larghero J, Dastot H, Shimamura A, Guardiola P, Esperou H, Ferry C, Jubert C, Feugeas JP, Henri A, Toubert A, Socié G, Baruchel A, Sigaux F, et al. Detection of somatic mosaicism and classification of Fanconi anemia patients by analysis of the FA/BRCA pathway. Blood. 105: 1329-36. PMID 15383454 DOI: 10.1182/blood-2004-05-1852  1
2004 Andreassen PR, D'Andrea AD, Taniguchi T. ATR couples FANCD2 monoubiquitination to the DNA-damage response. Genes & Development. 18: 1958-63. PMID 15314022 DOI: 10.1101/gad.1196104  0.52
2004 Wang X, D'Andrea AD. The interplay of Fanconi anemia proteins in the DNA damage response. Dna Repair. 3: 1063-9. PMID 15279794 DOI: 10.1016/j.dnarep.2004.04.005  1
2004 Wang X, Andreassen PR, D'Andrea AD. Functional interaction of monoubiquitinated FANCD2 and BRCA2/FANCD1 in chromatin. Molecular and Cellular Biology. 24: 5850-62. PMID 15199141 DOI: 10.1128/MCB.24.13.5850-5862.2004  1
2004 Hirsch B, Shimamura A, Moreau L, Baldinger S, Hag-alshiekh M, Bostrom B, Sencer S, D'Andrea AD. Association of biallelic BRCA2/FANCD1 mutations with spontaneous chromosomal instability and solid tumors of childhood. Blood. 103: 2554-9. PMID 14670928 DOI: 10.1182/blood-2003-06-1970  1
2003 Liu TX, Howlett NG, Deng M, Langenau DM, Hsu K, Rhodes J, Kanki JP, D'Andrea AD, Look AT. Knockdown of zebrafish Fancd2 causes developmental abnormalities via p53-dependent apoptosis. Developmental Cell. 5: 903-14. PMID 14667412 DOI: 10.1016/S1534-5807(03)00339-3  1
2003 Shimamura A, D'Andrea AD. Subtyping of Fanconi anemia patients: implications for clinical management. Blood. 102: 3459. PMID 14568911 DOI: 10.1182/blood-2003-04-1297  1
2003 Jin S, Mao H, Schnepp RW, Sykes SM, Silva AC, D'Andrea AD, Hua X. Menin associates with FANCD2, a protein involved in repair of DNA damage. Cancer Research. 63: 4204-10. PMID 12874027  1
2003 Taniguchi T, Tischkowitz M, Ameziane N, Hodgson SV, Mathew CG, Joenje H, Mok SC, D'Andrea AD. Disruption of the Fanconi anemia-BRCA pathway in cisplatin-sensitive ovarian tumors. Nature Medicine. 9: 568-74. PMID 12692539 DOI: 10.1038/nm852  1
2002 Nakanishi K, Taniguchi T, Ranganathan V, New HV, Moreau LA, Stotsky M, Mathew CG, Kastan MB, Weaver DT, D'Andrea AD. Interaction of FANCD2 and NBS1 in the DNA damage response. Nature Cell Biology. 4: 913-20. PMID 12447395 DOI: 10.1038/ncb879  1
2002 D'Andrea AD, Dahl N, Guinan EC, Shimamura A. Marrow failure. Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program. 58-72. PMID 12446419  1
2002 Shimamura A, Montes de Oca R, Svenson JL, Haining N, Moreau LA, Nathan DG, D'Andrea AD. A novel diagnostic screen for defects in the Fanconi anemia pathway. Blood. 100: 4649-54. PMID 12393398 DOI: 10.1182/blood-2002-05-1399  1
2002 Taniguchi T, Garcia-Higuera I, Andreassen PR, Gregory RC, Grompe M, D'Andrea AD. S-phase-specific interaction of the Fanconi anemia protein, FANCD2, with BRCA1 and RAD51. Blood. 100: 2414-20. PMID 12239151 DOI: 10.1182/blood-2002-01-0278  0.52
2002 Taniguchi T, Garcia-Higuera I, Xu B, Andreassen PR, Gregory RC, Kim ST, Lane WS, Kastan MB, D'Andrea AD. Convergence of the fanconi anemia and ataxia telangiectasia signaling pathways. Cell. 109: 459-72. PMID 12086603  0.52
2002 Howlett NG, Taniguchi T, Olson S, Cox B, Waisfisz Q, De Die-Smulders C, Persky N, Grompe M, Joenje H, Pals G, Ikeda H, Fox EA, D'Andrea AD. Biallelic inactivation of BRCA2 in Fanconi anemia. Science (New York, N.Y.). 297: 606-9. PMID 12065746 DOI: 10.1126/science.1073834  1
2001 Akkari YM, Bateman RL, Reifsteck CA, D'Andrea AD, Olson SB, Grompe M. The 4N cell cycle delay in Fanconi anemia reflects growth arrest in late S phase. Molecular Genetics and Metabolism. 74: 403-12. PMID 11749045 DOI: 10.1006/mgme.2001.3259  1
2001 Yang Y, Kuang Y, Montes De Oca R, Hays T, Moreau L, Lu N, Seed B, D'Andrea AD. Targeted disruption of the murine Fanconi anemia gene, Fancg/Xrcc9. Blood. 98: 3435-40. PMID 11719385 DOI: 10.1182/blood.V98.12.3435  1
2001 Nakanishi K, Moran A, Hays T, Kuang Y, Fox E, Garneau D, Montes de Oca R, Grompe M, D'Andrea AD. Functional analysis of patient-derived mutations in the Fanconi anemia gene, FANCG/XRCC9. Experimental Hematology. 29: 842-9. PMID 11438206 DOI: 10.1016/S0301-472X(01)00663-4  1
2001 Barber DL, Beattie BK, Mason JM, Nguyen MHH, Yoakim M, Neel BG, D'Andrea AD, Frank DA. A common epitope is shared by activated signal transducer and activator of transcription-5 (STAT5) and the phosphorylated erythropoietin receptor: Implications for the docking model of STAT activation Blood. 97: 2230-2237. PMID 11290583 DOI: 10.1182/blood.V97.8.2230  1
2001 Noll M, Bateman RL, D'Andrea AD, Grompe M. Preclinical protocol for in vivo selection of hematopoietic stem cells corrected by gene therapy in Fanconi anemia group C. Molecular Therapy : the Journal of the American Society of Gene Therapy. 3: 14-23. PMID 11162306 DOI: 10.1006/mthe.2000.0226  1
1999 Garcia-Higuera I, Kuang Y, D'Andrea AD. The molecular and cellular biology of Fanconi anemia Current Opinion in Hematology. 6: 83-88. PMID 10088637 DOI: 10.1097/00062752-199903000-00005  1
1998 D'Andrea A, Pellman D. Deubiquitinating enzymes: a new class of biological regulators. Critical Reviews in Biochemistry and Molecular Biology. 33: 337-52. PMID 9827704 DOI: 10.1080/10409239891204251  1
1998 D'Andrea AD, Serhan CN. Relieving the ltch Nature Genetics. 18: 97-99. PMID 9462731 DOI: 10.1038/ng0298-97  1
1997 Barber DL, Mason JM, Fukazawa T, Reedquist KA, Druker BJ, Band H, D'Andrea AD. Erythropoietin and interleukin-3 activate tyrosine phosphorylation of CBL and association with CRK adaptor proteins. Blood. 89: 3166-74. PMID 9129019  1
1997 Luo H, Rose P, Barber D, Hanratty WP, Lee S, Roberts TM, D'Andrea AD, Dearolf CR. Mutation in the Jak kinase JH2 domain hyperactivates Drosophila and mammalian Jak-Stat pathways. Molecular and Cellular Biology. 17: 1562-71. PMID 9032284 DOI: 10.1128/MCB.17.3.1562  1
1996 Zhu Y, Carroll M, Papa FR, Hochstrasser M, D'Andrea AD. DUB-1, a deubiquitinating enzyme with growth-suppressing activity Proceedings of the National Academy of Sciences of the United States of America. 93: 3275-3279. PMID 8622927 DOI: 10.1073/pnas.93.8.3275  1
1994 Barber DL, Demartino JC, Showers MO, D'Andrea AD. A dominant negative erythropoietin (EPO) receptor inhibits EPO-dependent growth and blocks F-gp55-dependent transformation Molecular and Cellular Biology. 14: 2257-2265. PMID 8139531 DOI: 10.1128/MCB.14.4.2257  1
1994 Boussiotis VA, Barber DL, Nakarai T, Freeman GJ, Gribben JG, Bernstein GM, D'Andrea AD, Ritz J, Nadler LM. Prevention of T cell anergy by signaling through the gamma c chain of the IL-2 receptor. Science (New York, N.Y.). 266: 1039-42. PMID 7973657 DOI: 10.1126/science.7973657  1
1994 Barber DL, D'Andrea AD. Erythropoietin and interleukin-2 activate distinct JAK kinase family members Molecular and Cellular Biology. 14: 6506-6514. PMID 7935373 DOI: 10.1128/MCB.14.10.6506  1
1994 Yamashita T, Barber DL, Zhu Y, Wu N, D'Andrea AD. The Fanconi anemia polypeptide FACC is localized to the cytoplasm Proceedings of the National Academy of Sciences of the United States of America. 91: 6712-6716. PMID 7517562 DOI: 10.1073/pnas.91.14.6712  1
1993 Showers MO, DeMartino JC, Saito Y, D'Andrea AD. Fusion of the Erythropoietin Receptor and the Friend Spleen Focus-Forming Virus gp55 Glycoprotein Transforms a Factor-Dependent Hematopoietic Cell Line Molecular and Cellular Biology. 13: 739-748. PMID 8423798 DOI: 10.1128/MCB.13.2.739  1
1992 D'Andrea AD, Moreau JF, Showers MO. Molecular mimicry of erythropoietin by the spleen focus-forming virus gp55 glycoprotein: the first stage of Friend virus-induced erythroleukemia Bba - Reviews On Cancer. 1114: 31-41. PMID 1390869 DOI: 10.1016/0304-419X(92)90004-I  1
1992 Showers MO, D'Andrea AD. Subunit structure and transmembrane signaling of the erythropoietin receptor International Review of Cytology. 137: 99-120. PMID 1336006 DOI: 10.1016/S0074-7696(08)62601-7  1
1992 Zon LI, Moreau JF, Koo JW, Mathey-Prevot B, D'Andrea AD. The erythropoietin receptor transmembrane region is necessary for activation by the Friend spleen focus-forming virus gp55 glycoprotein. Molecular and Cellular Biology. 12: 2949-57. PMID 1320192 DOI: 10.1128/MCB.12.7.2949  1
1991 D'Andrea AD, Yoshimura A, Youssoufian H, Zon LI, Koo JW, Lodish HF. The cytoplasmic region of the erythropoietin receptor contains nonoverlapping positive and negative growth-regulatory domains. Molecular and Cellular Biology. 11: 1980-7. PMID 1848667 DOI: 10.1128/MCB.11.4.1980  1
1990 Budarf M, Huebner K, Emanuel B, Croce CM, Copeland NG, Jenkins NA, D'Andrea AD. Assignment of the erythropoietin receptor (EPOR) gene to mouse chromosome 9 and human chromosome 19 Genomics. 8: 575-578. PMID 1962754 DOI: 10.1016/0888-7543(90)90047-X  1
1987 D'Andrea AD, Packer RJ, Rorke LB, Bilaniuk LT, Sutton LN, Bruce DA, Schut L. Pineocytomas of childhood. A reappraisal of natural history and response to therapy Cancer. 59: 1353-1357. PMID 3815306 DOI: 10.1002/1097-0142(19870401)59:7<1353::AID-CNCR2820590720>3.0.CO;2-4  1
Show low-probability matches.