Year |
Citation |
Score |
2020 |
El-Mahdy MA, Abdelghany TM, Hemann C, Ewees MG, Mahgoup EM, Eid MS, Shalaan MT, Alzarie YA, Zweier JL. Chronic Cigarette Smoke Exposure Triggers a Vicious Cycle of Leukocyte and Endothelial-Mediated Oxidant Stress that Results in Vascular Dysfunction. American Journal of Physiology. Heart and Circulatory Physiology. PMID 32412791 DOI: 10.1152/Ajpheart.00657.2019 |
0.313 |
|
2020 |
Zweier JL, Ilangovan G. Regulation of Nitric Oxide Metabolism and Vascular Tone by Cytoglobin. Antioxidants & Redox Signaling. PMID 31880165 DOI: 10.1089/Ars.2019.7881 |
0.351 |
|
2020 |
Ismail R, El-Sayed E, Mansour A, Hemann C, El-Mahdy M, Zweier J. Thymoquinone protects against cigarette smoke extract-induced vascular dysfunction through inhibition of the RhoA/Rho-kinase signaling pathway (849.1) The Faseb Journal. 28: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.08873 |
0.304 |
|
2019 |
Tan X, Ji K, Wang X, Yao R, Han G, Villamena F, Zweier J, Song Y, Rockenbauer A, Liu Y. Discriminative Detection of Biothiols through Thiol-Trapping Technique using Methanethiosulfonate Trityl Probe and Electron Paramagnetic Resonance Spectroscopy. Angewandte Chemie (International Ed. in English). PMID 31657108 DOI: 10.1002/Ange.201912832 |
0.321 |
|
2019 |
Headley CA, Hoffman CN, Freisen JM, Han Y, Macklin JM, Zweier JL, Rockenbauer A, Kuret J, Villamena FA. Membrane-specific spin trap, 5-dodecylcarbamoyl-5-N-dodecylacetamide-1-pyroline-N-oxide (diCPO): theoretical, bioorthogonal fluorescence imaging and EPR studies. Organic & Biomolecular Chemistry. PMID 31328213 DOI: 10.1039/C9Ob01334B |
0.331 |
|
2019 |
Boslett J, Reddy N, Alzarie YA, Zweier JL. Inhibition of CD38 with the thiazoloquin(az)olin(on)e 78c protects the heart against post-ischemic injury. The Journal of Pharmacology and Experimental Therapeutics. PMID 30635470 DOI: 10.1124/Jpet.118.254557 |
0.323 |
|
2018 |
Kang PT, Chen CL, Lin P, Zhang L, Zweier JL, Chen YR. Mitochondrial complex I in the post-ischemic heart reperfusion-mediated oxidative injury and protein cysteine sulfonation. Journal of Molecular and Cellular Cardiology. PMID 30031815 DOI: 10.1016/J.Yjmcc.2018.07.244 |
0.3 |
|
2018 |
Abdelghany TM, Ismail RS, Mansoor FA, Zweier JR, Lowe F, Zweier JL. Cigarette smoke constituents cause endothelial nitric oxide synthase dysfunction and uncoupling due to depletion of tetrahydrobiopterin with degradation of GTP cyclohydrolase. Nitric Oxide : Biology and Chemistry. PMID 29524646 DOI: 10.1016/J.Niox.2018.02.009 |
0.335 |
|
2018 |
Tan X, Tao S, Liu W, Rockenbauer A, Villamena FA, Zweier JL, Song Y, Liu Y. Synthesis and Characterization of Perthiatriarylmethyl Radical and Its Dendritic Derivatives with High Sensitivity and Selectivity to Superoxide Radical. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 29505165 DOI: 10.1002/Chem.201800134 |
0.328 |
|
2018 |
Boslett J, Helal M, Chini E, Zweier JL. Genetic deletion of CD38 confers post-ischemic myocardial protection through preserved pyridine nucleotides. Journal of Molecular and Cellular Cardiology. PMID 29476764 DOI: 10.1016/J.Yjmcc.2018.02.015 |
0.335 |
|
2017 |
Varadharaj S, Kelly OJ, Khayat RN, Kumar PS, Ahmed N, Zweier JL. Role of Dietary Antioxidants in the Preservation of Vascular Function and the Modulation of Health and Disease. Frontiers in Cardiovascular Medicine. 4: 64. PMID 29164133 DOI: 10.3389/Fcvm.2017.00064 |
0.367 |
|
2017 |
Tan X, Chen L, Song Y, Rockenbauer A, Villamena FA, Zweier JL, Liu Y. Thiol-dependent reduction of the triester and triamide derivatives of Finland trityl radical triggers O2-dependent superoxide production. Chemical Research in Toxicology. PMID 28759716 DOI: 10.1021/Acs.Chemrestox.7B00086 |
0.363 |
|
2017 |
Zhou D, Hemann C, Boslett J, Luo A, Zweier JL, Liu X. Oxygen binding and nitric oxide dioxygenase activity of cytoglobin are altered to different extents by cysteine modification. Febs Open Bio. 7: 845-853. PMID 28593139 DOI: 10.1002/2211-5463.12230 |
0.332 |
|
2017 |
Liu X, El-Mahdy MA, Boslett J, Varadharaj S, Hemann C, Abdelghany TM, Ismail RS, Little SC, Zhou D, Thuy LT, Kawada N, Zweier JL. Cytoglobin regulates blood pressure and vascular tone through nitric oxide metabolism in the vascular wall. Nature Communications. 8: 14807. PMID 28393874 DOI: 10.1038/Ncomms14807 |
0.327 |
|
2017 |
Zhang B, Novitskaya T, Wheeler DG, Xu Z, Chepurko E, Huttinger R, He H, Varadharaj S, Zweier JL, Song Y, Xu M, Harrell FE, Su YR, Absi T, Kohr MJ, et al. Kcnj11 Ablation Is Associated With Increased Nitro-Oxidative Stress During Ischemia-Reperfusion Injury: Implications for Human Ischemic Cardiomyopathy. Circulation. Heart Failure. 10. PMID 28209764 DOI: 10.1161/Circheartfailure.116.003523 |
0.336 |
|
2017 |
Boslett J, Hemann C, Zhao YJ, Lee HC, Zweier JL. Luteolinidin protects the post-ischemic heart through CD38 inhibition with preservation of NAD(P)(H). The Journal of Pharmacology and Experimental Therapeutics. PMID 28108596 DOI: 10.1124/Jpet.116.239459 |
0.353 |
|
2016 |
Liu W, Nie J, Tan X, Liu H, Yu N, Han G, Zhu Y, Villamena FA, Song Y, Zweier JL, Liu Y. Synthesis and Characterization of PEGylated Trityl Radicals: Effect of PEGylation on Physicochemical Properties. The Journal of Organic Chemistry. PMID 28005365 DOI: 10.1021/Acs.Joc.6B02590 |
0.353 |
|
2016 |
Dhimitruka I, Alzarie YA, Hemann C, Samouilov A, Zweier JL. Trityl radicals in perfluorocarbon emulsions as stable, sensitive, and biocompatible oximetry probes. Bioorganic & Medicinal Chemistry Letters. PMID 27836400 DOI: 10.1016/J.Bmcl.2016.10.066 |
0.353 |
|
2016 |
Griendling KK, Touyz RM, Zweier JL, Dikalov S, Chilian W, Chen YR, Harrison DG, Bhatnagar A. Measurement of Reactive Oxygen Species, Reactive Nitrogen Species, and Redox-Dependent Signaling in the Cardiovascular System: A Scientific Statement From the American Heart Association. Circulation Research. PMID 27418630 DOI: 10.1161/Res.0000000000000110 |
0.326 |
|
2016 |
Velayutham M, Hemann CF, Cardounel AJ, Zweier JL. Sulfite Oxidase Activity of Cytochrome c: Role of Hydrogen Peroxide. Biochemistry and Biophysics Reports. 5: 96-104. PMID 26709389 DOI: 10.1016/J.Bbrep.2015.11.025 |
0.351 |
|
2015 |
Reyes LA, Boslett J, Varadharaj S, De Pascali F, Hemann C, Druhan LJ, Ambrosio G, El-Mahdy M, Zweier JL. Depletion of NADP(H) due to CD38 activation triggers endothelial dysfunction in the postischemic heart. Proceedings of the National Academy of Sciences of the United States of America. 112: 11648-53. PMID 26297248 DOI: 10.1073/Pnas.1505556112 |
0.768 |
|
2015 |
Conklin DJ, Guo Y, Jagatheesan G, Kilfoil PJ, Haberzettl P, Hill BG, Baba SP, Guo L, Wetzelberger K, Obal D, Rokosh DG, Prough RA, Prabhu SD, Velayutham M, Zweier JL, et al. Genetic Deficiency of Glutathione S-Transferase P Increases Myocardial Sensitivity to Ischemia-Reperfusion Injury. Circulation Research. 117: 437-49. PMID 26169370 DOI: 10.1161/Circresaha.114.305518 |
0.336 |
|
2015 |
Xie L, Talukder MA, Sun J, Varadharaj S, Zweier JL. Liposomal tetrahydrobiopterin preserves eNOS coupling in the post-ischemic heart conferring in vivo cardioprotection. Journal of Molecular and Cellular Cardiology. PMID 26116866 DOI: 10.1016/J.Yjmcc.2015.06.015 |
0.391 |
|
2015 |
Varadharaj S, Porter K, Pleister A, Wannemacher J, Sow A, Jarjoura D, Zweier JL, Khayat RN. Endothelial nitric oxide synthase uncoupling: a novel pathway in OSA induced vascular endothelial dysfunction. Respiratory Physiology & Neurobiology. 207: 40-7. PMID 25534145 DOI: 10.1016/J.Resp.2014.12.012 |
0.316 |
|
2015 |
Silbajoris R, Linak W, Shenderova O, Winterrowd C, Chang HC, Zweier JL, Kota A, Dailey LA, Nunn N, Bromberg PA, Samet JM. Detonation nanodiamond toxicity in human airway epithelial cells is modulated by air oxidation Diamond and Related Materials. 58: 16-23. DOI: 10.1016/J.Diamond.2015.05.007 |
0.334 |
|
2014 |
Scheitlin CG, Nair DM, Crestanello JA, Zweier JL, Alevriadou BR. Fluid Mechanical Forces and Endothelial Mitochondria: A Bioengineering Perspective. Cellular and Molecular Bioengineering. 7: 483-496. PMID 25530817 DOI: 10.1007/S12195-014-0357-4 |
0.338 |
|
2014 |
Lee MC, Velayutham M, Komatsu T, Hille R, Zweier JL. Measurement and characterization of superoxide generation from xanthine dehydrogenase: a redox-regulated pathway of radical generation in ischemic tissues. Biochemistry. 53: 6615-23. PMID 25243829 DOI: 10.1021/Bi500582R |
0.404 |
|
2014 |
Quarrie R, Lee DS, Reyes L, Erdahl W, Pfeiffer DR, Zweier JL, Crestanello JA. Mitochondrial uncoupling does not decrease reactive oxygen species production after ischemia-reperfusion. American Journal of Physiology. Heart and Circulatory Physiology. 307: H996-H1004. PMID 25085966 DOI: 10.1152/Ajpheart.00189.2014 |
0.766 |
|
2014 |
De Pascali F, Hemann C, Samons K, Chen CA, Zweier JL. Hypoxia and reoxygenation induce endothelial nitric oxide synthase uncoupling in endothelial cells through tetrahydrobiopterin depletion and S-glutathionylation. Biochemistry. 53: 3679-88. PMID 24758136 DOI: 10.1021/Bi500076R |
0.38 |
|
2014 |
Bobko AA, Dhimitruka I, Zweier JL, Khramtsov VV. Fourier transform EPR spectroscopy of trityl radicals for multifunctional assessment of chemical microenvironment. Angewandte Chemie (International Ed. in English). 53: 2735-8. PMID 24488710 DOI: 10.1002/Anie.201310841 |
0.33 |
|
2014 |
Chen YR, Zweier JL. Cardiac mitochondria and reactive oxygen species generation. Circulation Research. 114: 524-37. PMID 24481843 DOI: 10.1161/Circresaha.114.300559 |
0.379 |
|
2014 |
Moldovan NI, Anghelina M, Varadharaj S, Butt OI, Wang T, Yang F, Moldovan L, Zweier JL. Reoxygenation-derived toxic reactive oxygen/nitrogen species modulate the contribution of bone marrow progenitor cells to remodeling after myocardial infarction. Journal of the American Heart Association. 3: e000471. PMID 24419735 DOI: 10.1161/Jaha.113.000471 |
0.317 |
|
2014 |
Das A, Gopalakrishnan B, Druhan LJ, Wang TY, De Pascali F, Rockenbauer A, Racoma I, Varadharaj S, Zweier JL, Cardounel AJ, Villamena FA. Reversal of SIN-1-induced eNOS dysfunction by the spin trap, DMPO, in bovine aortic endothelial cells via eNOS phosphorylation. British Journal of Pharmacology. 171: 2321-34. PMID 24405159 DOI: 10.1111/Bph.12572 |
0.389 |
|
2013 |
Chen CA, De Pascali F, Basye A, Hemann C, Zweier JL. Redox modulation of endothelial nitric oxide synthase by glutaredoxin-1 through reversible oxidative post-translational modification. Biochemistry. 52: 6712-23. PMID 23977830 DOI: 10.1021/Bi400404S |
0.37 |
|
2013 |
Liu X, Tong J, Zweier JR, Follmer D, Hemann C, Ismail RS, Zweier JL. Differences in oxygen-dependent nitric oxide metabolism by cytoglobin and myoglobin account for their differing functional roles. The Febs Journal. 280: 3621-31. PMID 23710929 DOI: 10.1111/Febs.12352 |
0.368 |
|
2013 |
Song Y, Liu Y, Hemann C, Villamena FA, Zweier JL. Esterified dendritic TAM radicals with very high stability and enhanced oxygen sensitivity. The Journal of Organic Chemistry. 78: 1371-6. PMID 23343531 DOI: 10.1021/Jo301849K |
0.324 |
|
2013 |
Talukder MA, Elnakish MT, Yang F, Nishijima Y, Alhaj MA, Velayutham M, Hassanain HH, Zweier JL. Cardiomyocyte-specific overexpression of an active form of Rac predisposes the heart to increased myocardial stunning and ischemia-reperfusion injury. American Journal of Physiology. Heart and Circulatory Physiology. 304: H294-302. PMID 23161879 DOI: 10.1152/Ajpheart.00367.2012 |
0.353 |
|
2013 |
Chen Z, Reyes LA, Johnson DH, Velayutham M, Yang C, Samouilov A, Zweier JL. Fast gated EPR imaging of the beating heart: spatiotemporally resolved 3D imaging of free-radical distribution during the cardiac cycle. Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 69: 594-601. PMID 22473660 DOI: 10.1002/Mrm.24250 |
0.763 |
|
2013 |
Velayutham M, Zweier JL. Nitric Oxide Signaling in Biology Messenger. 2: 1-18. DOI: 10.1166/Msr.2013.1018 |
0.312 |
|
2012 |
Kohr MJ, Roof SR, Zweier JL, Ziolo MT. Modulation of myocardial contraction by peroxynitrite. Frontiers in Physiology. 3: 468. PMID 23248603 DOI: 10.3389/Fphys.2012.00468 |
0.316 |
|
2012 |
Obal D, Dai S, Keith R, Dimova N, Kingery J, Zheng YT, Zweier J, Velayutham M, Prabhu SD, Li Q, Conklin D, Yang D, Bhatnagar A, Bolli R, Rokosh G. Cardiomyocyte-restricted overexpression of extracellular superoxide dismutase increases nitric oxide bioavailability and reduces infarct size after ischemia/reperfusion. Basic Research in Cardiology. 107: 305. PMID 23099819 DOI: 10.1007/S00395-012-0305-1 |
0.414 |
|
2012 |
Li H, Hemann C, Abdelghany TM, El-Mahdy MA, Zweier JL. Characterization of the mechanism and magnitude of cytoglobin-mediated nitrite reduction and nitric oxide generation under anaerobic conditions. The Journal of Biological Chemistry. 287: 36623-33. PMID 22896706 DOI: 10.1074/Jbc.M112.342378 |
0.392 |
|
2012 |
Quarrie R, Lee DS, Steinbaugh G, Cramer B, Erdahl W, Pfeiffer DR, Zweier JL, Crestanello JA. Ischemic preconditioning preserves mitochondrial membrane potential and limits reactive oxygen species production. The Journal of Surgical Research. 178: 8-17. PMID 22763215 DOI: 10.1016/J.Jss.2012.05.090 |
0.322 |
|
2012 |
Liu X, Follmer D, Zweier JR, Huang X, Hemann C, Liu K, Druhan LJ, Zweier JL. Characterization of the function of cytoglobin as an oxygen-dependent regulator of nitric oxide concentration. Biochemistry. 51: 5072-82. PMID 22577939 DOI: 10.1021/Bi300291H |
0.326 |
|
2012 |
Kundu TK, Velayutham M, Zweier JL. Aldehyde oxidase functions as a superoxide generating NADH oxidase: an important redox regulated pathway of cellular oxygen radical formation. Biochemistry. 51: 2930-9. PMID 22404107 DOI: 10.1021/Bi3000879 |
0.388 |
|
2012 |
Caia GL, Efimova OV, Velayutham M, El-Mahdy MA, Abdelghany TM, Kesselring E, Petryakov S, Sun Z, Samouilov A, Zweier JL. Organ specific mapping of in vivo redox state in control and cigarette smoke-exposed mice using EPR/NMR co-imaging. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 216: 21-7. PMID 22296801 DOI: 10.1016/J.Jmr.2011.10.017 |
0.31 |
|
2012 |
Biondi R, Ambrosio G, De Pascali F, Tritto I, Capodicasa E, Druhan LJ, Hemann C, Zweier JL. HPLC analysis of tetrahydrobiopterin and its pteridine derivatives using sequential electrochemical and fluorimetric detection: application to tetrahydrobiopterin autoxidation and chemical oxidation. Archives of Biochemistry and Biophysics. 520: 7-16. PMID 22286026 DOI: 10.1016/J.Abb.2012.01.010 |
0.395 |
|
2012 |
Lee HL, Chen CL, Yeh ST, Zweier JL, Chen YR. Biphasic modulation of the mitochondrial electron transport chain in myocardial ischemia and reperfusion. American Journal of Physiology. Heart and Circulatory Physiology. 302: H1410-22. PMID 22268109 DOI: 10.1152/Ajpheart.00731.2011 |
0.359 |
|
2012 |
Komarov DA, Dhimitruka I, Kirilyuk IA, Trofimiov DG, Grigor'ev IA, Zweier JL, Khramtsov VV. Electron paramagnetic resonance monitoring of ischemia-induced myocardial oxygen depletion and acidosis in isolated rat hearts using soluble paramagnetic probes. Magnetic Resonance in Medicine. 68: 649-55. PMID 22162021 DOI: 10.1002/Mrm.23251 |
0.363 |
|
2012 |
Giedt RJ, Yang C, Zweier JL, Matzavinos A, Alevriadou BR. Mitochondrial fission in endothelial cells after simulated ischemia/reperfusion: role of nitric oxide and reactive oxygen species. Free Radical Biology & Medicine. 52: 348-56. PMID 22100972 DOI: 10.1016/J.Freeradbiomed.2011.10.491 |
0.356 |
|
2011 |
Cai M, Huttinger ZM, He H, Zhang W, Li F, Goodman LA, Wheeler DG, Druhan LJ, Zweier JL, Dwyer KM, He G, d'Apice AJ, Robson SC, Cowan PJ, Gumina RJ. Transgenic over expression of ectonucleotide triphosphate diphosphohydrolase-1 protects against murine myocardial ischemic injury. Journal of Molecular and Cellular Cardiology. 51: 927-35. PMID 21939667 DOI: 10.1016/J.Yjmcc.2011.09.003 |
0.321 |
|
2011 |
Zweier JL, Chen CA, Talukder MA. Cardiac resynchronization therapy and reverse molecular remodeling: importance of mitochondrial redox signaling. Circulation Research. 109: 716-9. PMID 21921269 DOI: 10.1161/Circresaha.111.253864 |
0.318 |
|
2011 |
Efimova OV, Caia GL, Sun Z, Petryakov S, Kesselring E, Samouilov A, Zweier JL. Standard-based method for proton-electron double resonance imaging of oxygen. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 212: 197-203. PMID 21807539 DOI: 10.1016/J.Jmr.2011.06.030 |
0.341 |
|
2011 |
Karuppiah K, Druhan LJ, Chen CA, Smith T, Zweier JL, Sessa WC, Cardounel AJ. Suppression of eNOS-derived superoxide by caveolin-1: a biopterin-dependent mechanism. American Journal of Physiology. Heart and Circulatory Physiology. 301: H903-11. PMID 21724868 DOI: 10.1152/Ajpheart.00936.2010 |
0.385 |
|
2011 |
Chen CA, Lin CH, Druhan LJ, Wang TY, Chen YR, Zweier JL. Superoxide induces endothelial nitric-oxide synthase protein thiyl radical formation, a novel mechanism regulating eNOS function and coupling. The Journal of Biological Chemistry. 286: 29098-107. PMID 21666221 DOI: 10.1074/Jbc.M111.240127 |
0.399 |
|
2011 |
Velayutham M, Hemann C, Zweier JL. Removal of H₂O₂ and generation of superoxide radical: role of cytochrome c and NADH. Free Radical Biology & Medicine. 51: 160-70. PMID 21545835 DOI: 10.1016/J.Freeradbiomed.2011.04.007 |
0.407 |
|
2011 |
Liu Y, Song Y, Rockenbauer A, Sun J, Hemann C, Villamena FA, Zweier JL. Synthesis of trityl radical-conjugated disulfide biradicals for measurement of thiol concentration. The Journal of Organic Chemistry. 76: 3853-60. PMID 21488696 DOI: 10.1021/Jo200265U |
0.355 |
|
2011 |
Nishijima Y, Sridhar A, Bonilla I, Velayutham M, Khan M, Terentyeva R, Li C, Kuppusamy P, Elton TS, Terentyev D, Györke S, Zweier JL, Cardounel AJ, Carnes CA. Tetrahydrobiopterin depletion and NOS2 uncoupling contribute to heart failure-induced alterations in atrial electrophysiology. Cardiovascular Research. 91: 71-9. PMID 21460065 DOI: 10.1093/Cvr/Cvr087 |
0.309 |
|
2011 |
Chen J, Chen CL, Alevriadou BR, Zweier JL, Chen YR. Excess no predisposes mitochondrial succinate-cytochrome c reductase to produce hydroxyl radical. Biochimica Et Biophysica Acta. 1807: 491-502. PMID 21406178 DOI: 10.1016/J.Bbabio.2011.03.001 |
0.431 |
|
2011 |
Mital R, Zhang W, Cai M, Huttinger ZM, Goodman LA, Wheeler DG, Ziolo MT, Dwyer KM, d'Apice AJ, Zweier JL, He G, Cowan PJ, Gumina RJ. Antioxidant network expression abrogates oxidative posttranslational modifications in mice. American Journal of Physiology. Heart and Circulatory Physiology. 300: H1960-70. PMID 21335461 DOI: 10.1152/Ajpheart.01285.2010 |
0.374 |
|
2011 |
Muir WW, Ilangovan G, Zweier JL, Moon-Massat PF, Rentko VT. Vital organ tissue oxygenation after serial normovolemic exchange transfusion with HBOC-201 in anesthetized swine. Shock (Augusta, Ga.). 35: 597-603. PMID 21330945 DOI: 10.1097/Shk.0B013E31821366F6 |
0.321 |
|
2011 |
Zweier JL, Chen CA, Druhan LJ. S-glutathionylation reshapes our understanding of endothelial nitric oxide synthase uncoupling and nitric oxide/reactive oxygen species-mediated signaling. Antioxidants & Redox Signaling. 14: 1769-75. PMID 21261471 DOI: 10.1089/Ars.2011.3904 |
0.405 |
|
2011 |
Joddar B, Reen RK, Firstenberg MS, Varadharaj S, McCord JM, Zweier JL, Gooch KJ. Protandim attenuates intimal hyperplasia in human saphenous veins cultured ex vivo via a catalase-dependent pathway. Free Radical Biology & Medicine. 50: 700-9. PMID 21167278 DOI: 10.1016/J.Freeradbiomed.2010.12.008 |
0.341 |
|
2011 |
Talukder MA, Yang F, Nishijima Y, Chen CA, Xie L, Mahamud SD, Kalyanasundaram A, Bonagura JD, Periasamy M, Zweier JL. Detrimental effects of thyroid hormone analog DITPA in the mouse heart: increased mortality with in vivo acute myocardial ischemia-reperfusion. American Journal of Physiology. Heart and Circulatory Physiology. 300: H702-11. PMID 21131480 DOI: 10.1152/Ajpheart.00514.2010 |
0.316 |
|
2011 |
Quarrie R, Cramer BM, Lee DS, Steinbaugh GE, Erdahl W, Pfeiffer DR, Zweier JL, Crestanello JA. Ischemic preconditioning decreases mitochondrial proton leak and reactive oxygen species production in the postischemic heart. The Journal of Surgical Research. 165: 5-14. PMID 21035133 DOI: 10.1016/J.Jss.2010.09.018 |
0.329 |
|
2011 |
Nishijima Y, Sridhar A, Zweier JL, Cardounel AJ, Carnes CA. Is NOS uncoupling the missing link between atrial fibrillation and chronic non-ischaemic cardiomyopathy? Reply Cardiovascular Research. 91: 557-558. DOI: 10.1093/Cvr/Cvr178 |
0.303 |
|
2011 |
Zweier JL, Yang F, Yang C, Varadharaj S, Chen C, Talukder MH. POSTCONDITIONING PROTECTS THE HEART AGAINST IN VIVO ISCHEMIA REPERFUSION INJURY WITH REDUCED INFARCTION AND DECREASED SUPEROXIDE GENERATION: COMPARISON WITH EARLY ISCHEMIC PRECONDITIONING IN RATS Journal of the American College of Cardiology. 57: E970. DOI: 10.1016/S0735-1097(11)60970-4 |
0.325 |
|
2011 |
Quarrie R, Lee D, Erdahl W, Pfeiffer D, Zweier J, Crestanello J. Increased Mitochondrial Sensitivity To Proton Leak Is Responsible For Decreased Reactive Oxygen Species Production In Ischemic Preconditioning Journal of Surgical Research. 165: 262-263. DOI: 10.1016/J.Jss.2010.11.443 |
0.324 |
|
2010 |
Chen CA, Wang TY, Varadharaj S, Reyes LA, Hemann C, Talukder MA, Chen YR, Druhan LJ, Zweier JL. S-glutathionylation uncouples eNOS and regulates its cellular and vascular function. Nature. 468: 1115-8. PMID 21179168 DOI: 10.1038/Nature09599 |
0.777 |
|
2010 |
Kim SU, Liu Y, Nash KM, Zweier JL, Rockenbauer A, Villamena FA. Fast reactivity of a cyclic nitrone-calix[4]pyrrole conjugate with superoxide radical anion: theoretical and experimental studies. Journal of the American Chemical Society. 132: 17157-73. PMID 21070040 DOI: 10.1021/Ja105198C |
0.367 |
|
2010 |
Liu Y, Villamena FA, Song Y, Sun J, Rockenbauer A, Zweier JL. Synthesis of 14N- and 15N-labeled trityl-nitroxide biradicals with strong spin-spin interaction and improved sensitivity to redox status and oxygen. The Journal of Organic Chemistry. 75: 7796-802. PMID 21028905 DOI: 10.1021/Jo1016844 |
0.341 |
|
2010 |
Ahmad R, Caia G, Potter LC, Petryakov S, Kuppusamy P, Zweier JL. In vivo multisite oximetry using EPR-NMR coimaging. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 207: 69-77. PMID 20850361 DOI: 10.1016/J.Jmr.2010.08.011 |
0.303 |
|
2010 |
Dhimitruka I, Grigorieva O, Zweier JL, Khramtsov VV. Synthesis, structure, and EPR characterization of deuterated derivatives of Finland trityl radical. Bioorganic & Medicinal Chemistry Letters. 20: 3946-9. PMID 20537895 DOI: 10.1016/J.Bmcl.2010.05.006 |
0.355 |
|
2010 |
Talukder MA, Yang F, Shimokawa H, Zweier JL. eNOS is required for acute in vivo ischemic preconditioning of the heart: effects of ischemic duration and sex. American Journal of Physiology. Heart and Circulatory Physiology. 299: H437-45. PMID 20525875 DOI: 10.1152/Ajpheart.00384.2010 |
0.348 |
|
2010 |
Vedam K, Nishijima Y, Druhan LJ, Khan M, Moldovan NI, Zweier JL, Ilangovan G. Role of heat shock factor-1 activation in the doxorubicin-induced heart failure in mice. American Journal of Physiology. Heart and Circulatory Physiology. 298: H1832-41. PMID 20363884 DOI: 10.1152/Ajpheart.01047.2009 |
0.303 |
|
2010 |
Chen W, Druhan LJ, Chen CA, Hemann C, Chen YR, Berka V, Tsai AL, Zweier JL. Peroxynitrite induces destruction of the tetrahydrobiopterin and heme in endothelial nitric oxide synthase: transition from reversible to irreversible enzyme inhibition. Biochemistry. 49: 3129-37. PMID 20184376 DOI: 10.1021/Bi9016632 |
0.367 |
|
2010 |
Liu Y, Villamena FA, Rockenbauer A, Zweier JL. Trityl-nitroxide biradicals as unique molecular probes for the simultaneous measurement of redox status and oxygenation. Chemical Communications (Cambridge, England). 46: 628-30. PMID 20062884 DOI: 10.1039/B919279D |
0.334 |
|
2010 |
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Han Z, Varadharaj S, Giedt RJ, Zweier JL, Szeto HH, Alevriadou BR. Mitochondria-derived reactive oxygen species mediate heme oxygenase-1 expression in sheared endothelial cells. The Journal of Pharmacology and Experimental Therapeutics. 329: 94-101. PMID 19131585 DOI: 10.1124/Jpet.108.145557 |
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Liu Y, Villamena FA, Zweier JL. Highly stable dendritic trityl radicals as oxygen and pH probe. Chemical Communications (Cambridge, England). 4336-8. PMID 18802562 DOI: 10.1039/B807406B |
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Presley T, Vedam K, Velayutham M, Zweier JL, Ilangovan G. Activation of Hsp90-eNOS and increased NO generation attenuate respiration of hypoxia-treated endothelial cells. American Journal of Physiology. Cell Physiology. 295: C1281-91. PMID 18787079 DOI: 10.1152/Ajpcell.00550.2007 |
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Xu Y, Liu B, Zweier JL, He G. Formation of hydrogen peroxide and reduction of peroxynitrite via dismutation of superoxide at reperfusion enhances myocardial blood flow and oxygen consumption in postischemic mouse heart. The Journal of Pharmacology and Experimental Therapeutics. 327: 402-10. PMID 18685120 DOI: 10.1124/Jpet.108.142372 |
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Chen CL, Chen J, Rawale S, Varadharaj S, Kaumaya PP, Zweier JL, Chen YR. Protein tyrosine nitration of the flavin subunit is associated with oxidative modification of mitochondrial complex II in the post-ischemic myocardium. The Journal of Biological Chemistry. 283: 27991-8003. PMID 18682392 DOI: 10.1074/Jbc.M802691200 |
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Dhimitruka I, Bobko AA, Hadad CM, Zweier JL, Khramtsov VV. Synthesis and characterization of amino derivatives of persistent trityl radicals as dual function pH and oxygen paramagnetic probes. Journal of the American Chemical Society. 130: 10780-7. PMID 18636723 DOI: 10.1021/Ja803083Z |
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Druhan LJ, Forbes SP, Pope AJ, Chen CA, Zweier JL, Cardounel AJ. Regulation of eNOS-derived superoxide by endogenous methylarginines. Biochemistry. 47: 7256-63. PMID 18553936 DOI: 10.1021/Bi702377A |
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Alzawahra WF, Talukder MA, Liu X, Samouilov A, Zweier JL. Heme proteins mediate the conversion of nitrite to nitric oxide in the vascular wall. American Journal of Physiology. Heart and Circulatory Physiology. 295: H499-508. PMID 18539756 DOI: 10.1152/Ajpheart.00374.2008 |
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Jones CI, Han Z, Presley T, Varadharaj S, Zweier JL, Ilangovan G, Alevriadou BR. Endothelial cell respiration is affected by the oxygen tension during shear exposure: role of mitochondrial peroxynitrite. American Journal of Physiology. Cell Physiology. 295: C180-91. PMID 18480296 DOI: 10.1152/Ajpcell.00549.2007 |
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Li H, Cui H, Kundu TK, Alzawahra W, Zweier JL. Nitric oxide production from nitrite occurs primarily in tissues not in the blood: critical role of xanthine oxidase and aldehyde oxidase. The Journal of Biological Chemistry. 283: 17855-63. PMID 18424432 DOI: 10.1074/Jbc.M801785200 |
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Liu Y, Villamena FA, Sun J, Xu Y, Dhimitruka I, Zweier JL. Synthesis and characterization of ester-derivatized tetrathiatriarylmethyl radicals as intracellular oxygen probes. The Journal of Organic Chemistry. 73: 1490-7. PMID 18201099 DOI: 10.1021/Jo7022747 |
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Dhimitruka I, Velayutham M, Bobko AA, Khramtsov VV, Villamena FA, Hadad CM, Zweier JL. Large-scale synthesis of a persistent trityl radical for use in biomedical EPR applications and imaging. Bioorganic & Medicinal Chemistry Letters. 17: 6801-5. PMID 17964156 DOI: 10.1016/J.Bmcl.2007.10.030 |
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Velayutham M, Muthukumaran RB, Sostaric JZ, McCraken J, Fishbein JC, Zweier JL. Interactions of the major metabolite of the cancer chemopreventive drug oltipraz with cytochrome c: a novel pathway for cancer chemoprevention. Free Radical Biology & Medicine. 43: 1076-85. PMID 17761303 DOI: 10.1016/J.Freeradbiomed.2007.06.022 |
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Khan M, Kutala VK, Vikram DS, Wisel S, Chacko SM, Kuppusamy ML, Mohan IK, Zweier JL, Kwiatkowski P, Kuppusamy P. Skeletal myoblasts transplanted in the ischemic myocardium enhance in situ oxygenation and recovery of contractile function. American Journal of Physiology. Heart and Circulatory Physiology. 293: H2129-39. PMID 17660391 DOI: 10.1152/Ajpheart.00677.2007 |
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Talukder MA, Kalyanasundaram A, Zhao X, Zuo L, Bhupathy P, Babu GJ, Cardounel AJ, Periasamy M, Zweier JL. Expression of SERCA isoform with faster Ca2+ transport properties improves postischemic cardiac function and Ca2+ handling and decreases myocardial infarction. American Journal of Physiology. Heart and Circulatory Physiology. 293: H2418-28. PMID 17630344 DOI: 10.1152/Ajpheart.00663.2007 |
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Cao Z, Zhu H, Zhang L, Zhao X, Zweier JL, Li Y. Antioxidants and phase 2 enzymes in cardiomyocytes: Chemical inducibility and chemoprotection against oxidant and simulated ischemia-reperfusion injury. Experimental Biology and Medicine (Maywood, N.J.). 231: 1353-64. PMID 16946404 DOI: 10.1177/153537020623100809 |
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Venkatakrishnan CD, Tewari AK, Moldovan L, Cardounel AJ, Zweier JL, Kuppusamy P, Ilangovan G. Heat shock protects cardiac cells from doxorubicin-induced toxicity by activating p38 MAPK and phosphorylation of small heat shock protein 27. American Journal of Physiology. Heart and Circulatory Physiology. 291: H2680-91. PMID 16782845 DOI: 10.1152/Ajpheart.00395.2006 |
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Zhu H, Zhang L, Itoh K, Yamamoto M, Ross D, Trush MA, Zweier JL, Li Y. Nrf2 controls bone marrow stromal cell susceptibility to oxidative and electrophilic stress. Free Radical Biology & Medicine. 41: 132-43. PMID 16781461 DOI: 10.1016/J.Freeradbiomed.2006.03.020 |
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Xia Y, Berlowitz CO, Zweier JL. PIN inhibits nitric oxide and superoxide production from purified neuronal nitric oxide synthase. Biochimica Et Biophysica Acta. 1760: 1445-9. PMID 16781079 DOI: 10.1016/J.Bbagen.2006.04.007 |
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Deng Y, Pandian RP, Ahmad R, Kuppusamy P, Zweier JL. Application of magnetic field over-modulation for improved EPR linewidth measurements using probes with Lorentzian lineshape. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 181: 254-61. PMID 16759891 DOI: 10.1016/J.Jmr.2006.05.010 |
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Pandian RP, Dang V, Manoharan PT, Zweier JL, Kuppusamy P. Effect of nitrogen dioxide on the EPR property of lithium octa-n-butoxy 2,3-naphthalocyanine (LiNc-BuO) microcrystals. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 181: 154-61. PMID 16690337 DOI: 10.1016/J.Jmr.2006.04.004 |
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Biondi R, Ambrosio G, Liebgott T, Cardounel AJ, Bettini M, Tritto I, Zweier JL. Hydroxylation of D-phenylalanine as a novel approach to detect hydroxyl radicals: application to cardiac pathophysiology. Cardiovascular Research. 71: 322-30. PMID 16626670 DOI: 10.1016/J.Cardiores.2006.03.005 |
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Chen YR, Chen CL, Yeh A, Liu X, Zweier JL. Direct and indirect roles of cytochrome b in the mediation of superoxide generation and NO catabolism by mitochondrial succinate-cytochrome c reductase. The Journal of Biological Chemistry. 281: 13159-68. PMID 16531408 DOI: 10.1074/Jbc.M513627200 |
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Li H, He G, Deng Y, Kuppusamy P, Zweier JL. In vivo proton electron double resonance imaging of the distribution and clearance of nitroxide radicals in mice. Magnetic Resonance in Medicine. 55: 669-75. PMID 16463344 DOI: 10.1002/Mrm.20804 |
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2006 |
Nadolski G, Cardounel AJ, Zweier JL, Lockwood SF. The synthesis and aqueous superoxide anion scavenging of water-dispersible lutein esters. Bioorganic & Medicinal Chemistry Letters. 16: 775-81. PMID 16314095 DOI: 10.1016/J.Bmcl.2005.11.024 |
0.315 |
|
2006 |
Ilangovan G, Venkatakrishnan CD, Bratasz A, Osinbowale S, Cardounel AJ, Zweier JL, Kuppusamy P. Heat shock-induced attenuation of hydroxyl radical generation and mitochondrial aconitase activity in cardiac H9c2 cells. American Journal of Physiology. Cell Physiology. 290: C313-24. PMID 16162655 DOI: 10.1152/Ajpcell.00362.2005 |
0.343 |
|
2006 |
Tritto I, Wang P, Kuppusamy P, Giraldez R, Zweier JL, Ambrosio G. The anti-anginal drug trimetazidine reduces neutrophil-mediated cardiac reperfusion injury. Journal of Cardiovascular Pharmacology. 46: 89-98. PMID 15965360 DOI: 10.1097/01.Fjc.0000164091.81198.A3 |
0.363 |
|
2006 |
Zhao X, He G, Chen YR, Pandian RP, Kuppusamy P, Zweier JL. Endothelium-derived nitric oxide regulates postischemic myocardial oxygenation and oxygen consumption by modulation of mitochondrial electron transport. Circulation. 111: 2966-72. PMID 15939832 DOI: 10.1161/Circulationaha.104.527226 |
0.398 |
|
2006 |
Pandian RP, Kim YI, Woodward PM, Zweier JL, Manoharan PT, Kuppusamy P. The open molecular framework of paramagnetic lithium octabutoxy-naphthalocyanine: Implications for the detection of oxygen and nitric oxide using EPR spectroscopy Journal of Materials Chemistry. 16: 3609-3618. DOI: 10.1039/B517976A |
0.362 |
|
2006 |
Dumitrescu C, He G, Zweier JL. P059. Ischemic preconditioning improves cardiac function by increasing mitochondrial oxygen metabolism in the postischemic heart Nitric Oxide. 14: 36. DOI: 10.1016/J.Niox.2006.04.121 |
0.327 |
|
2005 |
Villamena FA, Merle JK, Hadad CM, Zweier JL. Superoxide radical anion adduct of 5,5-dimethyl-1-pyrroline N-oxide (DMPO). 2. The thermodynamics of decay and EPR spectral properties. The Journal of Physical Chemistry. A. 109: 6089-98. PMID 16833946 DOI: 10.1021/Jp0524330 |
0.361 |
|
2005 |
Villamena FA, Merle JK, Hadad CM, Zweier JL. Superoxide radical anion adduct of 5,5-dimethyl-1-pyrroline n-oxide (DMPO). 1. The thermodynamics of formation and its acidity. The Journal of Physical Chemistry. A. 109: 6083-8. PMID 16833945 DOI: 10.1021/Jp052431F |
0.332 |
|
2005 |
Villamena FA, Hadad CM, Zweier JL. Comparative DFT study of the spin trapping of methyl, mercapto, hydroperoxy, superoxide, and nitric oxide radicals by various substituted cyclic nitrones. The Journal of Physical Chemistry. A. 109: 1662-74. PMID 16833491 DOI: 10.1021/Jp0451492 |
0.342 |
|
2005 |
Chen YR, Chen CL, Zhang L, Green-Church KB, Zweier JL. Superoxide generation from mitochondrial NADH dehydrogenase induces self-inactivation with specific protein radical formation. The Journal of Biological Chemistry. 280: 37339-48. PMID 16150735 DOI: 10.1074/Jbc.M503936200 |
0.351 |
|
2005 |
Locigno EJ, Zweier JL, Villamena FA. Nitric oxide release from the unimolecular decomposition of the superoxide radical anion adduct of cyclic nitrones in aqueous medium. Organic & Biomolecular Chemistry. 3: 3220-7. PMID 16106305 DOI: 10.1039/B507530K |
0.391 |
|
2005 |
Chen YR, Chen CL, Liu X, He G, Zweier JL. Involvement of phospholipid, biomembrane integrity, and NO peroxidase activity in the NO catabolism by cytochrome c oxidase. Archives of Biochemistry and Biophysics. 439: 200-10. PMID 15963451 DOI: 10.1016/J.Abb.2005.05.014 |
0.336 |
|
2005 |
Velayutham M, Villamena FA, Navamal M, Fishbein JC, Zweier JL. Glutathione-mediated formation of oxygen free radicals by the major metabolite of oltipraz. Chemical Research in Toxicology. 18: 970-5. PMID 15962931 DOI: 10.1021/Tx049687H |
0.383 |
|
2005 |
Zhu H, Itoh K, Yamamoto M, Zweier JL, Li Y. Role of Nrf2 signaling in regulation of antioxidants and phase 2 enzymes in cardiac fibroblasts: protection against reactive oxygen and nitrogen species-induced cell injury. Febs Letters. 579: 3029-36. PMID 15896789 DOI: 10.1016/J.Febslet.2005.04.058 |
0.375 |
|
2005 |
Li H, Cui H, Liu X, Zweier JL. Xanthine oxidase catalyzes anaerobic transformation of organic nitrates to nitric oxide and nitrosothiols: characterization of this mechanism and the link between organic nitrate and guanylyl cyclase activation. The Journal of Biological Chemistry. 280: 16594-600. PMID 15695823 DOI: 10.1074/Jbc.M411905200 |
0.305 |
|
2005 |
Velayutham M, Villamena FA, Fishbein JC, Zweier JL. Cancer chemopreventive oltipraz generates superoxide anion radical. Archives of Biochemistry and Biophysics. 435: 83-8. PMID 15680910 DOI: 10.1016/J.Abb.2004.11.028 |
0.387 |
|
2005 |
Cardounel AJ, Xia Y, Zweier JL. Endogenous methylarginines modulate superoxide as well as nitric oxide generation from neuronal nitric-oxide synthase: differences in the effects of monomethyl- and dimethylarginines in the presence and absence of tetrahydrobiopterin. The Journal of Biological Chemistry. 280: 7540-9. PMID 15574418 DOI: 10.1074/Jbc.M410241200 |
0.322 |
|
2004 |
Villamena FA, Rockenbauer A, Gallucci J, Velayutham M, Hadad CM, Zweier JL. Spin trapping by 5-carbamoyl-5-methyl-1-pyrroline N-oxide (AMPO): theoretical and experimental studies. The Journal of Organic Chemistry. 69: 7994-8004. PMID 15527282 DOI: 10.1021/Jo049244I |
0.329 |
|
2004 |
Chen YR, Chen CL, Liu X, Li H, Zweier JL, Mason RP. Involvement of protein radical, protein aggregation, and effects on NO metabolism in the hypochlorite-mediated oxidation of mitochondrial cytochrome c. Free Radical Biology & Medicine. 37: 1591-603. PMID 15477010 DOI: 10.1016/J.Freeradbiomed.2004.07.013 |
0.34 |
|
2004 |
Ilangovan G, Osinbowale S, Bratasz A, Bonar M, Cardounel AJ, Zweier JL, Kuppusamy P. Heat shock regulates the respiration of cardiac H9c2 cells through upregulation of nitric oxide synthase. American Journal of Physiology. Cell Physiology. 287: C1472-81. PMID 15475520 DOI: 10.1152/Ajpcell.00103.2004 |
0.307 |
|
2004 |
Samouilov A, Roubaud V, Kuppusamy P, Zweier JL. Kinetic analysis-based quantitation of free radical generation in EPR spin trapping Analytical Biochemistry. 334: 145-154. PMID 15464963 DOI: 10.1016/J.Ab.2004.07.026 |
0.345 |
|
2004 |
Kuppusamy P, Zweier JL. Cardiac applications of EPR imaging Nmr in Biomedicine. 17: 226-239. PMID 15366025 DOI: 10.1002/Nbm.912 |
0.356 |
|
2004 |
Ilangovan G, Zweier JL, Kuppusamy P. Mechanism of oxygen-induced EPR line broadening in lithium phthalocyanine microcrystals Journal of Magnetic Resonance. 170: 42-48. PMID 15324756 DOI: 10.1016/J.Jmr.2004.05.018 |
0.336 |
|
2004 |
Liu X, Cheng C, Zorko N, Cronin S, Chen YR, Zweier JL. Biphasic modulation of vascular nitric oxide catabolism by oxygen. American Journal of Physiology. Heart and Circulatory Physiology. 287: H2421-6. PMID 15271663 DOI: 10.1152/Ajpheart.00487.2004 |
0.369 |
|
2004 |
Jackson HL, Cardounel AJ, Zweier JL, Lockwood SF. Synthesis, characterization, and direct aqueous superoxide anion scavenging of a highly water-dispersible astaxanthin-amino acid conjugate. Bioorganic & Medicinal Chemistry Letters. 14: 3985-91. PMID 15225712 DOI: 10.1016/J.Bmcl.2004.05.038 |
0.31 |
|
2004 |
Crowther JE, Kutala VK, Kuppusamy P, Ferguson JS, Beharka AA, Zweier JL, McCormack FX, Schlesinger LS. Pulmonary surfactant protein a inhibits macrophage reactive oxygen intermediate production in response to stimuli by reducing NADPH oxidase activity. Journal of Immunology (Baltimore, Md. : 1950). 172: 6866-74. PMID 15153505 DOI: 10.4049/Jimmunol.172.11.6866 |
0.319 |
|
2004 |
Villamena FA, Zweier JL. Detection of reactive oxygen and nitrogen species by EPR spin trapping. Antioxidants & Redox Signaling. 6: 619-29. PMID 15130289 DOI: 10.1089/152308604773934387 |
0.358 |
|
2004 |
Foss BJ, Sliwka HR, Partali V, Cardounel AJ, Zweier JL, Lockwood SF. Direct superoxide anion scavenging by a highly water-dispersible carotenoid phospholipid evaluated by electron paramagnetic resonance (EPR) spectroscopy. Bioorganic & Medicinal Chemistry Letters. 14: 2807-12. PMID 15125937 DOI: 10.1016/J.Bmcl.2004.03.061 |
0.359 |
|
2004 |
Ilangovan G, Liebgott T, Kutala VK, Petryakov S, Zweier JL, Kuppusamy P. EPR oximetry in the beating heart: myocardial oxygen consumption rate as an index of postischemic recovery. Magnetic Resonance in Medicine. 51: 835-42. PMID 15065258 DOI: 10.1002/Mrm.20000 |
0.347 |
|
2004 |
Ilangovan G, Zweier JL, Kuppusamy P. Microximetry: Simultaneous Determination of Oxygen Consumption and Free Radical Production Using Electron Paramagnetic Resonance Spectroscopy Methods in Enzymology. 381: 747-762. PMID 15063710 DOI: 10.1016/S0076-6879(04)81048-6 |
0.374 |
|
2004 |
Kutala VK, Parinandi NL, Zweier JL, Kuppusamy P. Reaction of superoxide with trityl radical: Implications for the determination of superoxide by spectrophotometry Archives of Biochemistry and Biophysics. 424: 81-88. PMID 15019839 DOI: 10.1016/J.Abb.2004.01.020 |
0.373 |
|
2004 |
Villamena FA, Hadad CM, Zweier JL. Theoretical study of the spin trapping of hydroxyl radical by cyclic nitrones: a density functional theory approach. Journal of the American Chemical Society. 126: 1816-29. PMID 14871114 DOI: 10.1021/Ja038838K |
0.314 |
|
2004 |
Li H, Samouilov A, Liu X, Zweier JL. Characterization of the effects of oxygen on xanthine oxidase-mediated nitric oxide formation. The Journal of Biological Chemistry. 279: 16939-46. PMID 14766900 DOI: 10.1074/Jbc.M314336200 |
0.384 |
|
2004 |
Chen YR, Chen CL, Chen W, Zweier JL, Augusto O, Radi R, Mason RP. Formation of protein tyrosine ortho-semiquinone radical and nitrotyrosine from cytochrome c-derived tyrosyl radical. The Journal of Biological Chemistry. 279: 18054-62. PMID 14761966 DOI: 10.1074/Jbc.M307706200 |
0.343 |
|
2004 |
Tiravanti E, Samouilov A, Zweier JL. Nitrosyl-heme complexes are formed in the ischemic heart: evidence of nitrite-derived nitric oxide formation, storage, and signaling in post-ischemic tissues. The Journal of Biological Chemistry. 279: 11065-73. PMID 14704151 DOI: 10.1074/Jbc.M311908200 |
0.401 |
|
2004 |
Rizzi C, Samouilov A, Kutala VK, Parinandi NL, Zweier JL, Kuppusamy P. Application of a trityl-based radical probe for measuring superoxide. Free Radical Biology & Medicine. 35: 1608-18. PMID 14680684 DOI: 10.1016/J.Freeradbiomed.2003.09.014 |
0.375 |
|
2004 |
Khramtsov VV, Grigor’ev IA, Lurie DJ, Foster MA, Zweier JL, Kuppusamy P. Spin pH and SH probes: enhancing functionality of EPR-based techniques Spectroscopy. 18: 213-225. DOI: 10.1155/2004/870630 |
0.314 |
|
2004 |
Xia Y, Biondi R, Liebgott T, Paolocci N, Cardounel A, Ambrosio G, Zweier JL. 1136-82 Tetrahydrobiopterin depletion leads to endothelial nitric oxide synthase dysfunction in ischemic hearts Journal of the American College of Cardiology. 43: A294. DOI: 10.1016/S0735-1097(04)91245-4 |
0.363 |
|
2003 |
Pandian RP, Kutala VK, Parinandi NL, Zweier JL, Kuppusamy P. Measurement of oxygen consumption in mouse aortic endothelial cells using a microparticulate oximetry probe Archives of Biochemistry and Biophysics. 420: 169-175. PMID 14622987 DOI: 10.1016/J.Abb.2003.09.008 |
0.349 |
|
2003 |
Pandian RP, Parinandi NL, Ilangovan G, Zweier JL, Kuppusamy P. Novel particulate spin probe for targeted determination of oxygen in cells and tissues Free Radical Biology and Medicine. 35: 1138-1148. PMID 14572616 DOI: 10.1016/S0891-5849(03)00496-9 |
0.341 |
|
2003 |
Zweier JL, He G, Samouilov A, Kuppusamy P. EPR spectroscopy and imaging of oxygen: Applications to the gastrointestinal tract Advances in Experimental Medicine and Biology. 530: 123-131. PMID 14562710 DOI: 10.1007/978-1-4615-0075-9_12 |
0.31 |
|
2003 |
Muscoli C, Cuzzocrea S, Riley DP, Zweier JL, Thiemermann C, Wang ZQ, Salvemini D. On the selectivity of superoxide dismutase mimetics and its importance in pharmacological studies. British Journal of Pharmacology. 140: 445-60. PMID 14522841 DOI: 10.1038/Sj.Bjp.0705430 |
0.314 |
|
2003 |
Roy S, Khanna S, Wallace WA, Lappalainen J, Rink C, Cardounel AJ, Zweier JL, Sen CK. Characterization of perceived hyperoxia in isolated primary cardiac fibroblasts and in the reoxygenated heart. The Journal of Biological Chemistry. 278: 47129-35. PMID 12952964 DOI: 10.1074/Jbc.M308703200 |
0.338 |
|
2003 |
Cardounel AJ, Dumitrescu C, Zweier JL, Lockwood SF. Direct superoxide anion scavenging by a disodium disuccinate astaxanthin derivative: Relative efficacy of individual stereoisomers versus the statistical mixture of stereoisomers by electron paramagnetic resonance imaging. Biochemical and Biophysical Research Communications. 307: 704-12. PMID 12893281 DOI: 10.1016/S0006-291X(03)01248-8 |
0.336 |
|
2003 |
Liebgott T, Li H, Deng Y, Zweier JL. Proton electron double resonance imaging (PEDRI) of the isolated beating rat heart. Magnetic Resonance in Medicine. 50: 391-9. PMID 12876716 DOI: 10.1002/Mrm.10534 |
0.352 |
|
2003 |
Cai Z, Manalo DJ, Wei G, Rodriguez ER, Fox-Talbot K, Lu H, Zweier JL, Semenza GL. Hearts from rodents exposed to intermittent hypoxia or erythropoietin are protected against ischemia-reperfusion injury. Circulation. 108: 79-85. PMID 12796124 DOI: 10.1161/01.Cir.0000078635.89229.8A |
0.317 |
|
2003 |
Velayutham M, Li H, Kuppusamy P, Zweier JL. Mapping ischemic risk region and necrosis in the isolated heart using EPR imaging Magnetic Resonance in Medicine. 49: 1181-1187. PMID 12768597 DOI: 10.1002/Mrm.10473 |
0.33 |
|
2003 |
Li H, Samouilov A, Liu X, Zweier JL. Characterization of the magnitude and kinetics of xanthine oxidase-catalyzed nitrate reduction: evaluation of its role in nitrite and nitric oxide generation in anoxic tissues. Biochemistry. 42: 1150-9. PMID 12549937 DOI: 10.1021/Bi026385A |
0.373 |
|
2003 |
Parinandi NL, Kleinberg MA, Usatyuk PV, Cummings RJ, Pennathur A, Cardounel AJ, Zweier JL, Garcia JG, Natarajan V. Hyperoxia-induced NAD(P)H oxidase activation and regulation by MAP kinases in human lung endothelial cells. American Journal of Physiology. Lung Cellular and Molecular Physiology. 284: L26-38. PMID 12388366 DOI: 10.1152/Ajplung.00123.2002 |
0.327 |
|
2003 |
Janiszewski M, Souza HP, Liu X, Pedro MA, Zweier JL, Laurindo FR. Overestimation of NADH-driven vascular oxidase activity due to lucigenin artifacts. Free Radical Biology & Medicine. 32: 446-53. PMID 11864784 DOI: 10.1016/S0891-5849(01)00828-0 |
0.375 |
|
2002 |
Song Y, Cardounel AJ, Zweier JL, Xia Y. Inhibition of superoxide generation from neuronal nitric oxide synthase by heat shock protein 90: implications in NOS regulation. Biochemistry. 41: 10616-22. PMID 12186546 DOI: 10.1021/Bi026060U |
0.3 |
|
2002 |
He G, Samouilov A, Kuppusamy P, Zweier JL. In vivo imaging of free radicals: Applications from mouse to man Molecular and Cellular Biochemistry. 234: 359-367. PMID 12162454 DOI: 10.1023/A:1015994629341 |
0.331 |
|
2002 |
Samouilov A, Zweier JL. Analytical implications of iron dithiocarbamates for measurement of nitric oxide. Methods in Enzymology. 352: 506-22. PMID 12125375 DOI: 10.1016/S0076-6879(02)52044-9 |
0.302 |
|
2002 |
Li Y, Seacat A, Kuppusamy P, Zweier JL, Yager JD, Trush MA. Copper redox-dependent activation of 2-tert-butyl(1,4)hydroquinone: formation of reactive oxygen species and induction of oxidative DNA damage in isolated DNA and cultured rat hepatocytes. Mutation Research. 518: 123-33. PMID 12113763 DOI: 10.1016/S1383-5718(02)00073-6 |
0.331 |
|
2002 |
Li H, Ma L, Hsia CJC, Zweier JL, Kuppusamy P. Polynitroxyl-albumin (PNA) enhances myocardial infarction therapeutic effect of Tempol in rat hearts subjected to regional ischemia-reperfusion Free Radical Biology and Medicine. 32: 712-719. PMID 11937297 DOI: 10.1016/S0891-5849(02)00762-1 |
0.33 |
|
2002 |
He G, Deng Y, Li H, Kuppusamy P, Zweier JL. EPR/NMR co-imaging for anatomic registration of free-radical images. Magnetic Resonance in Medicine. 47: 571-8. PMID 11870845 DOI: 10.1002/Mrm.10077 |
0.321 |
|
2002 |
Ilangovan G, Manivannan A, Li H, Yanagi H, Zweier JL, Kuppusamy P. A naphthalocyanine-based EPR probe for localized measurements of tissue oxygenation. Free Radical Biology & Medicine. 32: 139-47. PMID 11796202 DOI: 10.1016/S0891-5849(01)00784-5 |
0.337 |
|
2002 |
Souza HP, Liu X, Samouilov A, Kuppusamy P, Laurindo FRM, Zweier JL. Quantitation of superoxide generation and substrate utilization by vascular NAD(P)H oxidase American Journal of Physiology - Heart and Circulatory Physiology. 282. PMID 11788393 DOI: 10.1152/Ajpheart.00482.2001 |
0.334 |
|
2002 |
Lurie DJ, Li H, Petryakov S, Zweier JL. Development of a PEDRI free-radical imager using a 0.38 T clinical MRI system. Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 47: 181-6. PMID 11754457 DOI: 10.1002/Mrm.10029 |
0.303 |
|
2002 |
Ellis SJ, Velayutham M, Velan SS, Petersen EF, Zweier JL, Kuppusamy P, Spencer RG. EPR oxygen mapping (EPROM) of engineered cartilage grown in a hollow-fiber bioreactor. Magnetic Resonance in Medicine. 46: 819-26. PMID 11590660 DOI: 10.1002/Mrm.1262 |
0.342 |
|
2002 |
Villamena FA, Zweier JL. Superoxide radical trapping and spin adduct decay of 5-tert-butoxycarbonyl-5-methyl-1-pyrroline N-oxide (BocMPO): kinetics and theoretical analysis Journal of the Chemical Society-Perkin Transactions 1. 1340-1344. DOI: 10.1039/B201734B |
0.347 |
|
2002 |
Ilangovan G, Pal R, Zweier JL, Kuppusamy P. Electrochemical preparation and EPR studies of lithium phthalocyanine. 4. Effect of nitric oxide Journal of Physical Chemistry B. 106: 11929-11935. DOI: 10.1021/Jp026360L |
0.316 |
|
2002 |
Shankar R, Kuppusamy P, Zhou Y, Goldson A, Zweier J, Sridhar R. In vivo measurements of tumor oxygenation and metabolism using electron paramagnetic resonance spectroscopy/imaging International Journal of Radiation Oncology*Biology*Physics. 54: 118. DOI: 10.1016/S0360-3016(02)03259-5 |
0.305 |
|
2001 |
Song Y, Zweier JL, Xia Y. Determination of the enhancing action of HSP90 on neuronal nitric oxide synthase by EPR spectroscopy. American Journal of Physiology. Cell Physiology. 281: C1819-24. PMID 11698240 DOI: 10.1152/Ajpcell.2001.281.6.C1819 |
0.309 |
|
2001 |
Duilio C, Ambrosio G, Kuppusamy P, DiPaula A, Becker LC, Zweier JL. Neutrophils are primary source of O2 radicals during reperfusion after prolonged myocardial ischemia. American Journal of Physiology. Heart and Circulatory Physiology. 280: H2649-57. PMID 11356621 DOI: 10.1152/Ajpheart.2001.280.6.H2649 |
0.412 |
|
2001 |
Paolocci N, Biondi R, Bettini M, Lee CI, Berlowitz CO, Rossi R, Xia Y, Ambrosio G, L'Abbate A, Kass DA, Zweier JL. Oxygen radical-mediated reduction in basal and agonist-evoked NO release in isolated rat heart. Journal of Molecular and Cellular Cardiology. 33: 671-9. PMID 11341236 DOI: 10.1006/Jmcc.2000.1334 |
0.364 |
|
2001 |
Li H, Samouilov A, Liu X, Zweier JL. Characterization of the magnitude and kinetics of xanthine oxidase-catalyzed nitrite reduction. Evaluation of its role in nitric oxide generation in anoxic tissues. The Journal of Biological Chemistry. 276: 24482-9. PMID 11312267 DOI: 10.1074/Jbc.M011648200 |
0.379 |
|
2001 |
Zweier JL, Fertmann J, Wei G. Nitric oxide and peroxynitrite in postischemic myocardium. Antioxidants & Redox Signaling. 3: 11-22. PMID 11294189 DOI: 10.1089/152308601750100443 |
0.423 |
|
2001 |
Kuppusamy P, Shankar RA, Roubaud VM, Zweier JL. Whole body detection and imaging of nitric oxide generation in mice following cardiopulmonary arrest: Detection of intrinsic nitrosoheme complexes0 Magnetic Resonance in Medicine. 45: 700-707. PMID 11283999 DOI: 10.1002/Mrm.1093 |
0.378 |
|
2001 |
Souza HP, Laurindo FR, Ziegelstein RC, Berlowitz CO, Zweier JL. Vascular NAD(P)H oxidase is distinct from the phagocytic enzyme and modulates vascular reactivity control. American Journal of Physiology. Heart and Circulatory Physiology. 280: H658-67. PMID 11158964 DOI: 10.1152/Ajpheart.2001.280.2.H658 |
0.374 |
|
2001 |
Janiszewski M, Pedro M, Souza H, Zweier J, Laurindo F. Artifacts related to lucigenin chemiluminescence for superoxide detection in a vascular system Critical Care. 5: 20. DOI: 10.1186/Cc1353 |
0.386 |
|
2000 |
Zorov DB, Filburn CR, Klotz LO, Zweier JL, Sollott SJ. Reactive oxygen species (ROS)-induced ROS release: A new phenomenon accompanying induction of the mitochondrial permeability transition in cardiac myocytes Journal of Experimental Medicine. 192: 1001-1014. PMID 11015441 DOI: 10.1084/Jem.192.7.1001 |
0.337 |
|
2000 |
Velan SS, Spencer RGS, Zweier JL, Kuppusamy P. Electron paramagnetic resonance oxygen mapping (EPROM): Direct visualization of oxygen concentration in tissue Magnetic Resonance in Medicine. 43: 804-809. PMID 10861874 DOI: 10.1002/1522-2594(200006)43:6<804::Aid-Mrm5>3.0.Co;2-B |
0.326 |
|
2000 |
Giraldez RR, Panda A, Zweier JL. Endothelial dysfunction does not require loss of endothelial nitric oxide synthase. American Journal of Physiology. Heart and Circulatory Physiology. 278: H2020-7. PMID 10843901 DOI: 10.1152/Ajpheart.2000.278.6.H2020 |
0.371 |
|
2000 |
Sanders SP, Bassett DJP, Harrison SJ, Pearse D, Zweier JL, Becker PM. Measurements of free radicals in isolated, ischemic lungs and lung mitochondria Lung. 178: 105-118. PMID 10773136 DOI: 10.1007/S004080000013 |
0.378 |
|
2000 |
Hu Q, Zheng G, Zweier JL, Deshpande S, Irani K, Ziegelstein RC. NADPH oxidase activation increases the sensitivity of intracellular Ca2+ stores to inositol 1,4,5-trisphosphate in human endothelial cells. The Journal of Biological Chemistry. 275: 15749-57. PMID 10747906 DOI: 10.1074/Jbc.M000381200 |
0.309 |
|
2000 |
Sankarapandi S, Zweier JL. Evidence against the generation of free hydroxyl radicals from the interaction of copper,zinc-superoxide dismutase and hydrogen peroxide. The Journal of Biological Chemistry. 274: 34576-83. PMID 10574920 DOI: 10.1074/Jbc.274.49.34576 |
0.365 |
|
1999 |
Wei G, Dawson VL, Zweier JL. Role of neuronal and endothelial nitric oxide synthase in nitric oxide generation in the brain following cerebral ischemia. Biochimica Et Biophysica Acta. 1455: 23-34. PMID 10524226 DOI: 10.1016/S0925-4439(99)00051-4 |
0.347 |
|
1999 |
Salvemini D, Wang ZQ, Zweier JL, Samouilov A, Macarthur H, Misko TP, Currie MG, Cuzzocrea S, Sikorski JA, Riley DP. A nonpeptidyl mimic of superoxide dismutase with therapeutic activity in rats Science. 286: 304-306. PMID 10514375 DOI: 10.1126/Science.286.5438.304 |
0.347 |
|
1999 |
Lu R, Wang P, Wartofsky L, Sutton BD, Zweier JL, Bahn RS, Garrity J, Burman KD. Oxygen free radicals in interleukin-1beta-induced glycosaminoglycan production by retro-ocular fibroblasts from normal subjects and Graves' ophthalmopathy patients. Thyroid : Official Journal of the American Thyroid Association. 9: 297-303. PMID 10211608 DOI: 10.1089/Thy.1999.9.297 |
0.302 |
|
1999 |
He G, Shankar RA, Chzhan M, Samouilov A, Kuppusamy P, Zweier JL. Noninvasive measurement of anatomic structure and intraluminal oxygenation in the gastrointestinal tract of living mice with spatial and spectral EPR imaging. Proceedings of the National Academy of Sciences of the United States of America. 96: 4586-91. PMID 10200306 DOI: 10.1073/Pnas.96.8.4586 |
0.309 |
|
1999 |
Sankarapandi S, Zweier JL. Bicarbonate is required for the peroxidase function of Cu, Zn-superoxide dismutase at physiological pH. The Journal of Biological Chemistry. 274: 1226-32. PMID 9880490 DOI: 10.1074/Jbc.274.3.1226 |
0.326 |
|
1999 |
Kuppusamy P, Wang P, Shankar RA, Ma L, Trimble CE, Hsia CJ, Zweier JL. In vivo topical EPR spectroscopy and imaging of nitroxide free radicals and polynitroxyl-albumin. Magnetic Resonance in Medicine. 40: 806-11. PMID 9840823 DOI: 10.1002/Mrm.1910400604 |
0.327 |
|
1998 |
Krishna MC, Kuppusamy P, Afeworki M, Zweier JL, Cook JA, Subramanian S, Mitchell JB. Development of functional electron paramagnetic resonance imaging. Breast Disease. 10: 209-20. PMID 15687576 DOI: 10.3233/Bd-1998-103-420 |
0.301 |
|
1998 |
Xia Y, Tsai AL, Berka V, Zweier JL. Superoxide generation from endothelial nitric-oxide synthase. A Ca2+/calmodulin-dependent and tetrahydrobiopterin regulatory process. The Journal of Biological Chemistry. 273: 25804-8. PMID 9748253 DOI: 10.1074/Jbc.273.40.25804 |
0.346 |
|
1998 |
Hu Q, Xia Y, Corda S, Zweier JL, Ziegelstein RC. Hydrogen peroxide decreases pHi in human aortic endothelial cells by inhibiting Na+/H+ exchange. Circulation Research. 83: 644-51. PMID 9742060 DOI: 10.1161/01.Res.83.6.644 |
0.313 |
|
1998 |
Ha HC, Sirisoma NS, Kuppusamy P, Zweier JL, Woster PM, Casero RA. The natural polyamine spermine functions directly as a free radical scavenger Proceedings of the National Academy of Sciences of the United States of America. 95: 11140-11145. PMID 9736703 DOI: 10.1073/Pnas.95.19.11140 |
0.346 |
|
1998 |
Samouilov A, Kuppusamy P, Zweier JL. Evaluation of the magnitude and rate of nitric oxide production from nitrite in biological systems Archives of Biochemistry and Biophysics. 357: 1-7. PMID 9721176 DOI: 10.1006/Abbi.1998.0785 |
0.358 |
|
1998 |
Xia Y, Roman LJ, Masters BSS, Zweier JL. Inducible nitric-oxide synthase generates superoxide from the reductase domain Journal of Biological Chemistry. 273: 22635-22639. PMID 9712892 DOI: 10.1074/Jbc.273.35.22635 |
0.349 |
|
1998 |
Kuppusamy P, Shankar RA, Zweier JL. In vivo measurement of arterial and venous oxygenation in the rat using 3D spectral-spatial electron paramagnetic resonance imaging Physics in Medicine and Biology. 43: 1837-1844. PMID 9703045 DOI: 10.1088/0031-9155/43/7/003 |
0.337 |
|
1998 |
Zweier JL, Chzhan M, Samouilov A, Kuppusamy P. Electron paramagnetic resonance imaging of the rat heart Physics in Medicine and Biology. 43: 1823-1835. PMID 9703044 DOI: 10.1088/0031-9155/43/7/002 |
0.39 |
|
1998 |
Sankarapandi S, Zweier JL, Mukherjee G, Quinn MT, Huso DL. Measurement and characterization of superoxide generation in microglial cells: evidence for an NADPH oxidase-dependent pathway. Archives of Biochemistry and Biophysics. 353: 312-21. PMID 9606965 DOI: 10.1006/Abbi.1998.0658 |
0.388 |
|
1998 |
Samouilov A, Zweier JL. Development of chemiluminescence-based methods for specific quantitation of nitrosylated thiols. Analytical Biochemistry. 258: 322-30. PMID 9570848 DOI: 10.1006/Abio.1998.2609 |
0.315 |
|
1998 |
Wang P, Chen H, Qin H, Sankarapandi S, Becher MW, Wong PC, Zweier JL. Overexpression of human copper, zinc-superoxide dismutase (SOD1) prevents postischemic injury. Proceedings of the National Academy of Sciences of the United States of America. 95: 4556-60. PMID 9539776 DOI: 10.1073/Pnas.95.8.4556 |
0.382 |
|
1998 |
Roubaud V, Sankarapandi S, Kuppusamy P, Tordo P, Zweier JL. Quantitative measurement of superoxide generation and oxygen consumption from leukocytes using electron paramagnetic resonance spectroscopy Analytical Biochemistry. 257: 210-217. PMID 9514781 DOI: 10.1006/Abio.1997.2542 |
0.392 |
|
1998 |
Hu Q, Corda S, Zweier JL, Capogrossi MC, Ziegelstein RC. Hydrogen peroxide induces intracellular calcium oscillations in human aortic endothelial cells. Circulation. 97: 268-75. PMID 9462529 DOI: 10.1161/01.Cir.97.3.268 |
0.317 |
|
1998 |
Li Y, Zhu H, Kuppusamy P, Roubaud V, Zweier JL, Trush MA. Validation of lucigenin (bis-N-methylacridinium) as a chemilumigenic probe for detecting superoxide anion radical production by enzymatic and cellular systems. The Journal of Biological Chemistry. 273: 2015-23. PMID 9442038 DOI: 10.1074/Jbc.273.4.2015 |
0.32 |
|
1998 |
Giraldez R, Sun B, Zweier J, Becker L. Impaired endothelial-dependent vasodilation in viable postischemic myocardium results from reduced activity of nitric oxide synthase Journal of the American College of Cardiology. 31: 187. DOI: 10.1016/S0735-1097(98)81452-6 |
0.351 |
|
1997 |
Xia Y, Zweier JL. Direct measurement of nitric oxide generation from nitric oxide synthase. Proceedings of the National Academy of Sciences of the United States of America. 94: 12705-10. PMID 9356514 DOI: 10.1073/Pnas.94.23.12705 |
0.341 |
|
1997 |
Seacat AM, Kuppusamy P, Zweier JL, Yager JD. ESR identification of free radicals formed from the oxidation of catechol estrogens by Cu2+ Archives of Biochemistry and Biophysics. 347: 45-52. PMID 9344463 DOI: 10.1006/Abbi.1997.0323 |
0.317 |
|
1997 |
Xia Y, Zweier JL. Superoxide and peroxynitrite generation from inducible nitric oxide synthase in macrophages. Proceedings of the National Academy of Sciences of the United States of America. 94: 6954-8. PMID 9192673 DOI: 10.1073/Pnas.94.13.6954 |
0.329 |
|
1997 |
Roubaud V, Sankarapandi S, Kuppusamy P, Tordo P, Zweier JL. Quantitative measurement of superoxide generation using the spin trap 5- (diethoxyphosphoryl)-5-methyl-1-pyrroline-N-oxide Analytical Biochemistry. 247: 404-411. PMID 9177705 DOI: 10.1006/Abio.1997.2067 |
0.376 |
|
1997 |
Xu KY, Zweier JL, Becker LC. Hydroxyl radical inhibits sarcoplasmic reticulum Ca(2+)-ATPase function by direct attack on the ATP binding site. Circulation Research. 80: 76-81. PMID 8978325 DOI: 10.1161/01.Res.80.1.76 |
0.321 |
|
1997 |
Wang P, Zweier JL. Measurement of nitric oxide and peroxynitrite generation in the postischemic heart. Evidence for peroxynitrite-mediated reperfusion injury. The Journal of Biological Chemistry. 271: 29223-30. PMID 8910581 DOI: 10.1074/jbc.271.46.29223 |
0.313 |
|
1996 |
Primiano T, Kensler TW, Kuppusamy P, Zweier JL, Sutter TR. Induction of hepatic heme oxygenase-1 and ferritin in rats by cancer chemopreventive dithiolethiones Carcinogenesis. 17: 2291-2296. PMID 8968040 DOI: 10.1093/Carcin/17.11.2291 |
0.301 |
|
1996 |
Kuppusamy P, Wang P, Samouilov A, Zweier JL. Spatial mapping of nitric oxide generation in the ischemic heart using electron paramagnetic resonance imaging Magnetic Resonance in Medicine. 36: 212-218. PMID 8843374 DOI: 10.1002/Mrm.1910360207 |
0.373 |
|
1996 |
Kuppusamy P, Chzhan M, Wang P, Zweier JL. Three-dimensional gated EPR imaging of the beating heart: Time-resolved measurements of free radical distribution during the cardiac contractile cycle Magnetic Resonance in Medicine. 35: 323-328. PMID 8699943 DOI: 10.1002/Mrm.1910350309 |
0.334 |
|
1996 |
Xia Y, Dawson VL, Dawson TM, Snyder SH, Zweier JL. Nitric oxide synthase generates superoxide and nitric oxide in arginine-depleted cells leading to peroxynitrite-mediated cellular injury. Proceedings of the National Academy of Sciences of the United States of America. 93: 6770-4. PMID 8692893 DOI: 10.1073/Pnas.93.13.6770 |
0.344 |
|
1996 |
Kuppusamy P, Wang P, Zweier JL, Krishna MC, Mitchell JB, Ma L, Trimble CE, Hsia CJ. Electron paramagnetic resonance imaging of rat heart with nitroxide and polynitroxyl-albumin. Biochemistry. 35: 7051-7. PMID 8679530 DOI: 10.1021/Bi952857S |
0.38 |
|
1996 |
Fraticelli A, Serrano CV, Bochner BS, Capogrossi MC, Zweier JL. Hydrogen peroxide and superoxide modulate leukocyte adhesion molecule expression and leukocyte endothelial adhesion. Biochimica Et Biophysica Acta. 1310: 251-9. PMID 8599602 DOI: 10.1016/0167-4889(95)00169-7 |
0.393 |
|
1996 |
Zweier JL, Samouilov A, Chzhan M. Measurement of nitric oxide with a solid-state-char EPR probe. Journal of Magnetic Resonance. Series B. 109: 259-63. PMID 8542194 DOI: 10.1006/Jmrb.1995.9997 |
0.356 |
|
1996 |
Zweier JL, Chzhan M, Wang P, Kupppusamy P. Spatial and spectral-spatial EPR imaging of free radicals and oxygen in the heart Research On Chemical Intermediates. 22: 615-624. DOI: 10.1163/156856796X00241 |
0.37 |
|
1996 |
Kuppusamy P, Ohnishi ST, Numagami Y, Ohnishi T, Zweier JL. Imaging of nitric oxide generation in the rat brain Research On Chemical Intermediates. 22: 605-613. DOI: 10.1163/156856796X00232 |
0.365 |
|
1996 |
Zweier JL, Wang P, Samouilov A, Kuppusamy P. Enzyme independent formation of nitric oxide is triggered during myocardial ischemia and results in post ischemic injury Journal of the American College of Cardiology. 27: 102-103. DOI: 10.1016/S0735-1097(96)80621-8 |
0.356 |
|
1996 |
Giraldez RR, Broderick R, Xia Y, Sanders SP, Zweier JL. Loss of nitric oxide synthase activity in the post-ischemic heart: Evidence for acidosis induced enzyme denaturation Journal of the American College of Cardiology. 27: 101. DOI: 10.1016/S0735-1097(96)80616-4 |
0.359 |
|
1996 |
Dulio C, Ambrosio G, Kuppusamy P, Becker LC, Zweier JL. In vivo evidence that neutrophils become activated and generate oxygen radicals in reperfused hearts Journal of the American College of Cardiology. 27: 33. DOI: 10.1016/S0735-1097(96)80323-8 |
0.379 |
|
1995 |
Zweier JL, Wang P, Kuppusamy P. Direct measurement of nitric oxide generation in the ischemic heart using electron paramagnetic resonance spectroscopy Journal of Biological Chemistry. 270: 304-307. PMID 7814391 DOI: 10.1074/jbc.270.1.304 |
0.3 |
|
1995 |
Sanders SP, Zweier JL, Harrison SJ, Trush MA, Rembish SJ, Liu MC. Spontaneous oxygen radical production at sites of antigen challenge in allergic subjects American Journal of Respiratory and Critical Care Medicine. 151: 1725-1733. PMID 7767513 DOI: 10.1164/Ajrccm.151.6.7767513 |
0.334 |
|
1995 |
Kuppusamy P, Wang P, Zweier JL. Three‐dimensional spatial EPR imaging of the rat heart Magnetic Resonance in Medicine. 34: 99-105. PMID 7674904 DOI: 10.1002/Mrm.1910340115 |
0.322 |
|
1995 |
Kuppusamy P, Wang P, Zweier JL. Evaluation of nitroxides for the study of myocardial metabolism and oxygenation Magnetic Resonance in Chemistry. 33: S123-S128. DOI: 10.1002/Mrc.1260331319 |
0.365 |
|
1994 |
Zweier JL, Kuppusamy P, Thompson-Gorman S, Klunk D, Lutty GA. Measurement and characterization of free radical generation in reoxygenated human endothelial cells American Journal of Physiology - Cell Physiology. 266. PMID 8166233 DOI: 10.1152/Ajpcell.1994.266.3.C700 |
0.387 |
|
1994 |
Kuppusamy P, Chzhan M, Vij K, Shteynbuk M, Lefer DJ, Giannella E, Zweier JL. Three-dimensional spectral-spatial EPR imaging of free radicals in the heart: a technique for imaging tissue metabolism and oxygenation. Proceedings of the National Academy of Sciences of the United States of America. 91: 3388-92. PMID 8159757 DOI: 10.1073/Pnas.91.8.3388 |
0.356 |
|
1994 |
Sanders SP, Harrison SJ, Kuppusamy P, Sylvester JT, Zweier JL. A comparative study of EPR spin trapping and cytochrome c reduction techniques for the measurement of superoxide anions Free Radical Biology and Medicine. 16: 753-761. PMID 8070678 DOI: 10.1016/0891-5849(94)90190-2 |
0.364 |
|
1994 |
Chen K, Ng CE, Zweier JL, Kuppusamy P, Glickson JD, Swartz HM. Measurement of the intracellular concentration of oxygen in a cell perfusion system. Magnetic Resonance in Medicine. 31: 668-72. PMID 8057819 DOI: 10.1002/Mrm.1910310613 |
0.324 |
|
1994 |
Zweier JL, Broderick R, Kuppusamy P, Thompson-Gorman S, Lutty GA. Determination of the mechanism of free radical generation in human aortic endothelial cells exposed to anoxia and reoxygenation Journal of Biological Chemistry. 269: 24156-24162. PMID 7929072 DOI: 10.13016/M2Xs5Jh7K |
0.388 |
|
1994 |
Zweier JL, Chzhan M, Ewert U, Schneider G, Kuppusamy P. Development of a Highly Sensitive Probe for Measuring Oxygen in Biological Tissues Journal of Magnetic Resonance, Series B. 105: 52-57. PMID 7921671 DOI: 10.1006/Jmrb.1994.1099 |
0.353 |
|
1994 |
Zweier JL, Kuppusamy P. In vivo EPR spectroscopy of free radicals in the heart Environmental Health Perspectives. 102: 45-51. PMID 7705304 DOI: 10.1289/Ehp.94102S1045 |
0.369 |
|
1993 |
Shandelya SML, Kuppusamy P, Weisfeldt ML, Zweier JL. Evaluation of the role of polymorphonuclear leukocytes on contractile function in myocardial reperfusion injury: Evidence for plasma-mediated leukocyte activation Circulation. 87: 536-546. PMID 8381059 DOI: 10.1161/01.Cir.87.2.536 |
0.335 |
|
1993 |
Sanders SP, Zweier JL, Kuppusamy P, Harrison SJ, Bessert DJP, Gabrielson EW, Sylvester JT. Hyperoxic sheep pulmonary microvascular endothelial cells generate free radicals via mitochondrial electron transport Journal of Clinical Investigation. 91: 46-52. PMID 8380815 DOI: 10.1172/Jci116198 |
0.383 |
|
1993 |
Shandelya SML, Kuppusamy P, Herskowitz A, Weisfeldt ML, Zweier JL. Soluble complement receptor type 1 inhibits the complement pathway and prevents contractile failure in the postischemic heart: Evidence that complement activation is required for neutrophil-mediated reperfusion injury Circulation. 88: 2812-2826. PMID 8252695 DOI: 10.1161/01.Cir.88.6.2812 |
0.411 |
|
1993 |
Li Y, Kuppusamy P, Zweier J, Trush M. Generation of reactive oxygen from the copper-mediated oxidation of the benzene metabolite, 1,4-hydroquinone: Role in DNA damage Free Radical Biology and Medicine. 15: 540. DOI: 10.1016/0891-5849(93)90447-3 |
0.337 |
|
1993 |
Li Y, Kuppusamy P, Zweier J, Trush M. Chemical mechanism and biological effects of the SOD-accelerated oxidation of 1,4-hydroquinone Free Radical Biology and Medicine. 15: 475. DOI: 10.1016/0891-5849(93)90203-7 |
0.326 |
|
1992 |
Ambrosio G, Zweier JL, Flaherty JT. The relationship between oxygen radical generation and impairment of myocardial energy metabolism following post-ischemic reperfusion. Journal of Molecular and Cellular Cardiology. 23: 1359-74. PMID 1811055 DOI: 10.1016/0022-2828(91)90183-M |
0.407 |
|
1992 |
Povey AC, Wilson VL, Zweier JL, Kuppusamy P, O'Neill IK, Harris CC. Detection by 32P-postlabelling of DNA adducts induced by free radicals and unsaturated aldehydes formed during the aerobic decomposition of fecapentaene-12. Carcinogenesis. 13: 395-401. PMID 1547529 DOI: 10.1093/Carcin/13.3.395 |
0.343 |
|
1992 |
Grill HP, Zweier JL, Kuppusamy P, Weisfeldt ML, Flaherty JT. Direct measurement of myocardial free radical generation in an in vivo model: Effects of postischemic reperfusion and treatment with human recombinant superoxide dismutase Journal of the American College of Cardiology. 20: 1604-1611. PMID 1333498 DOI: 10.1016/0735-1097(92)90457-X |
0.382 |
|
1991 |
Guyton KZ, Bhan P, Kuppusamy P, Zweier JL, Trush MA, Kensler TW. Free radical-derived quinone methide mediates skin tumor promotion by butylated hydroxytoluene hydroperoxide: Expanded role for electrophiles in multistage carcinogenesis Proceedings of the National Academy of Sciences of the United States of America. 88: 946-950. PMID 1846971 DOI: 10.1073/Pnas.88.3.946 |
0.306 |
|
1991 |
Zweier JL, Thompson-Gorman S, Kuppusamy P. Measurement of oxygen concentrations in the intact beating heart using electron paramagnetic resonance spectroscopy: A technique for measuring oxygen concentrations in situ Journal of Bioenergetics and Biomembranes. 23: 855-871. PMID 1663949 DOI: 10.1007/Bf00786005 |
0.361 |
|
1991 |
Corretti MC, Koretsune Y, Kusuoka H, Chacko VP, Zweier JL, Marban E. Glycolytic inhibition and calcium overload as consequences of exogenously generated free radicals in rabbit hearts. The Journal of Clinical Investigation. 88: 1014-25. PMID 1653271 DOI: 10.1172/Jci115361 |
0.353 |
|
1990 |
Maupoil-David V, Rochette L, Zweier JL. Determination by electron paramagnetic resonance (EPR) spectroscopy of superoxide and hydroxyl free radical scavenging effects of sulfhydryl-containing substances Journal of Molecular and Cellular Cardiology. 22: S49. DOI: 10.1016/0022-2828(90)91676-X |
0.333 |
|
1989 |
Weisfeldt ML, Zweier J, Ambrosio G, Becker LC, Flaherty JT. Evidence that free radicals result in reperfusion injury in heart muscle. Basic Life Sciences. 49: 911-9. PMID 2855014 DOI: 10.1007/978-1-4684-5568-7_149 |
0.366 |
|
1989 |
Zweier JL, Duke SS, Kuppusamy P, Sylvester JT, Gabrielson EW. Electron paramagnetic resonance evidence that cellular oxygen toxicity is caused by the generation of superoxide and hydroxyl free radicals Febs Letters. 252: 12-16. PMID 2547649 DOI: 10.1016/0014-5793(89)80881-6 |
0.405 |
|
1989 |
Taffe BG, Zweier JL, Pannell LK, Kensler TW. Generation of reactive intermediates from the tumor promoter butylated hydroxytoluene hydroperoxide in isolated murine keratinocytes or by hematin. Carcinogenesis. 10: 1261-8. PMID 2472232 DOI: 10.1093/Carcin/10.7.1261 |
0.341 |
|
1988 |
Zweier JL, Rayburn BK, Flaherty JT, Weisfeldt ML. Recombinant superoxide dismutase reduces oxygen free radical concentrations in reperfused myocardium. The Journal of Clinical Investigation. 80: 1728-34. PMID 3680525 DOI: 10.1172/Jci113264 |
0.386 |
|
1988 |
Zweier JL, Kuppusamy P. Electron paramagnetic resonance measurements of free radicals in the intact beating heart: A technique for detection and characterization of free radicals in whole biological tissues Proceedings of the National Academy of Sciences of the United States of America. 85: 5703-5707. PMID 2840672 DOI: 10.1073/Pnas.85.15.5703 |
0.372 |
|
1988 |
Zweier JL, Kuppusamy P, Lutty GA. Measurement of endothelial cell free radical generation: Evidence for a central mechanism of free radical injury in postischemic tissues Proceedings of the National Academy of Sciences of the United States of America. 85: 4046-4050. PMID 2836868 DOI: 10.1073/Pnas.85.11.4046 |
0.4 |
|
1987 |
Zweier JL, Flaherty JT, Weisfeldt ML. Direct measurement of free radical generation following reperfusion of ischemic myocardium. Proceedings of the National Academy of Sciences of the United States of America. 84: 1404-7. PMID 3029779 DOI: 10.1016/S0022-2828(86)80267-X |
0.364 |
|
1987 |
Ambrosio G, Zweier JL, Jacobus WE, Weisfeldt ML, Flaherty JT. Improvement of postischemic myocardial function and metabolism induced by administration of deferoxamine at the time of reflow: the role of iron in the pathogenesis of reperfusion injury. Circulation. 76: 906-15. PMID 2820615 DOI: 10.1161/01.Cir.76.4.906 |
0.36 |
|
1987 |
WILLIAMS R, ZWEIER J, WEISFELDT M, FLAHERTY J. Effects of deferoxamine (DEF) on ischemic and reperfusion free radical concentrations Journal of Molecular and Cellular Cardiology. 19: S76-S76. DOI: 10.1016/S0022-2828(87)80852-0 |
0.323 |
|
1986 |
Hilton BD, Misra R, Zweier JL. Magnetic resonance studies of fredericamycin A: Evidence for O2-dependent free-radical formation Biochemistry. 25: 5533-5539. PMID 3022794 DOI: 10.1021/Bi00367A028 |
0.353 |
|
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