| Year |
Citation |
Score |
| 2019 |
Inzucchi SE, Viscoli CM, Young LH, Kernan WN. Diabetes prevention and cardiovascular complications. Diabetologia. PMID 31522231 DOI: 10.1007/S00125-019-04999-3 |
0.323 |
|
| 2019 |
Ma Y, Su KN, Pfau D, Rao VS, Wu X, Hu X, Leng L, Du X, Piecychna M, Bedi K, Campbell SG, Eichmann A, Testani JM, Margulies KB, Bucala R, ... Young LH, et al. Cardiomyocyte d-dopachrome tautomerase protects against heart failure. Jci Insight. 4. PMID 31484822 DOI: 10.1172/Jci.Insight.128900 |
0.357 |
|
| 2019 |
Pfau D, Thorn SL, Zhang J, Mikush N, Renaud JM, Klein R, deKemp RA, Wu X, Hu X, Sinusas AJ, Young LH, Tirziu D. Angiotensin Receptor Neprilysin Inhibitor Attenuates Myocardial Remodeling and Improves Infarct Perfusion in Experimental Heart Failure. Scientific Reports. 9: 5791. PMID 30962467 DOI: 10.1038/S41598-019-42113-0 |
0.385 |
|
| 2019 |
Spence JD, Viscoli CM, Inzucchi SE, Dearborn-Tomazos J, Ford GA, Gorman M, Furie KL, Lovejoy AM, Young LH, Kernan WN. Pioglitazone Therapy in Patients With Stroke and Prediabetes: A Post Hoc Analysis of the IRIS Randomized Clinical Trial. Jama Neurology. PMID 30734043 DOI: 10.1001/Jamaneurol.2019.0079 |
0.348 |
|
| 2018 |
Viscoli CM, Kent DM, Conwit R, Dearborn JL, Furie KL, Gorman M, Guarino PD, Inzucchi SE, Stuart A, Young LH, Kernan WN. Scoring System to Optimize Pioglitazone Therapy After Stroke Based on Fracture Risk. Stroke. STROKEAHA118022745. PMID 30580725 DOI: 10.1161/Strokeaha.118.022745 |
0.31 |
|
| 2018 |
Dearborn JL, Viscoli CM, Inzucchi SE, Young LH, Kernan WN. Metabolic syndrome identifies normal weight insulin-resistant stroke patients at risk for recurrent vascular disease. International Journal of Stroke : Official Journal of the International Stroke Society. 1747493018816425. PMID 30507360 DOI: 10.1177/1747493018816425 |
0.308 |
|
| 2018 |
Wang D, Hu X, Lee SH, Chen F, Jiang K, Tu Z, Liu Z, Du J, Wang L, Yin C, Liao Y, Shang H, Martin KA, Herzog RI, Young LH, et al. Diabetes Exacerbates Myocardial Ischemia/Reperfusion Injury by Down-Regulation of MicroRNA and Up-Regulation of O-GlcNAcylation. Jacc. Basic to Translational Science. 3: 350-362. PMID 30062222 DOI: 10.1016/J.Jacbts.2018.01.005 |
0.355 |
|
| 2018 |
Young LH, Viscoli CM, Schwartz GG, Inzucchi SE, Curtis JP, Gorman MJ, Furie KL, Conwit R, Spatz E, Lovejoy A, Abbott JD, Jacoby DL, Kolansky DM, Ling FS, Pfau SE, et al. Heart Failure After Ischemic Stroke or TIA in Insulin-Resistant Patients Without Diabetes Treated with Pioglitazone. Circulation. PMID 29934374 DOI: 10.1161/Circulationaha.118.034763 |
0.388 |
|
| 2018 |
INZUCCHI SE, VISCOLI CM, YOUNG LH, GORMAN MJ, CONWIT RA, SCHWARTZ GG, KERNAN W. What Mediated Pioglitazone's Cardiovascular (CV) Benefit in the IRIS Trial? Diabetes. 67: 17-LB. DOI: 10.2337/Db18-17-Lb |
0.316 |
|
| 2018 |
Yaghi S, Furie K, Viscoli CM, Kamel H, Gorman M, Dearborn J, Young LH, Inzucchi SE, Lovejoy AM, Kasner SE, Conwit R, Kernan WN. Abstract 101: Pioglitazone Prevents Stroke in Patients With a Recent TIA or Ischemic Stroke: a Secondary Analysis of the IRIS Trial Stroke. 49. DOI: 10.1161/Str.49.Suppl_1.101 |
0.351 |
|
| 2017 |
Perdigoto AL, Young LH, Inzucchi SE. Pioglitazone and cardiovascular risk reduction: time for a second look? Cardiovascular Endocrinology. 6: 55-61. PMID 31646121 DOI: 10.1097/Xce.0000000000000110 |
0.376 |
|
| 2017 |
Neuman RI, van Kalmthout JAM, Pfau DJ, Menendez DM, Young LH, Forrest JN. AMP-activated protein kinase and adenosine are both metabolic modulators regulating chloride secretion in the shark rectal gland (Squalus acanthias). American Journal of Physiology. Cell Physiology. PMID 29351415 DOI: 10.1152/Ajpcell.00171.2017 |
0.307 |
|
| 2017 |
Yaghi S, Furie KL, Viscoli CM, Kamel H, Gorman M, Dearborn J, Young LH, Inzucchi SE, Lovejoy AM, Kasner SE, Conwit R, Kernan WN. Pioglitazone Prevents Stroke in Patients with a Recent TIA or Ischemic Stroke: A Planned Secondary Analysis of the IRIS Trial. Circulation. PMID 29084736 DOI: 10.1161/Circulationaha.117.030458 |
0.332 |
|
| 2017 |
Young LH, Viscoli CM, Inzucchi SE, Kernan WN. Response by Young et al to Letters Regarding Article, "Cardiac Outcomes After Ischemic Stroke or Transient Ischemic Attack: Effects of Pioglitazone in Patients With Insulin Resistance Without Diabetes Mellitus". Circulation. 136: 1567-1568. PMID 29038213 DOI: 10.1161/Circulationaha.117.030513 |
0.394 |
|
| 2017 |
Kernan WN, Viscoli CM, Dearborn JL, Kent DM, Conwit R, Fayad P, Furie KL, Gorman M, Guarino PD, Inzucchi SE, Stuart A, Young LH. Targeting Pioglitazone Hydrochloride Therapy After Stroke or Transient Ischemic Attack According to Pretreatment Risk for Stroke or Myocardial Infarction. Jama Neurology. PMID 28975241 DOI: 10.1001/Jamaneurol.2017.2136 |
0.308 |
|
| 2017 |
Inzucchi SE, Viscoli CM, Young LH, Furie KL, Gorman M, Lovejoy AM, Dagogo-Jack S, Ismail-Beigi F, Korytkowski MT, Pratley RE, Schwartz GG, Kernan WN. Response to Comment on Inzucchi et al. Pioglitazone Prevents Diabetes in Patients With Insulin Resistance and Cerebrovascular Disease. Diabetes Care 2016;39:1684-1692. Diabetes Care. 40: e47-e48. PMID 28325804 DOI: 10.2337/Dci16-0048 |
0.356 |
|
| 2017 |
Young LH, Viscoli CM, Curtis JP, Inzucchi SE, Schwartz GG, Lovejoy AM, Furie KL, Gorman MJ, Conwit RA, Abbott JD, Jacoby DL, Kolansky DM, Pfau SE, Ling FS, Kernan WN, et al. Cardiac Outcomes After Ischemic Stroke or TIA: Effects of Pioglitazone in Patients with Insulin Resistance Without Diabetes. Circulation. PMID 28246237 DOI: 10.1161/Circulationaha.116.024863 |
0.411 |
|
| 2016 |
Viscoli CM, Inzucchi SE, Young LH, Insogna KL, Conwit R, Furie KL, Gorman M, Kelly MA, Lovejoy AM, Kernan WN. Pioglitazone and Risk for Bone Fracture: Safety Data from a Randomized Clinical Trial. The Journal of Clinical Endocrinology and Metabolism. jc20163237. PMID 27935736 DOI: 10.1210/Jc.2016-3237 |
0.301 |
|
| 2016 |
Bartulos O, Zhuang ZW, Huang Y, Mikush N, Suh C, Bregasi A, Wang L, Chang W, Krause DS, Young LH, Pober JS, Qyang Y. ISL1 cardiovascular progenitor cells for cardiac repair after myocardial infarction. Jci Insight. 1. PMID 27525311 DOI: 10.1172/Jci.Insight.80920 |
0.37 |
|
| 2016 |
Inzucchi SE, Viscoli CM, Young LH, Furie KL, Gorman M, Lovejoy AM, Dagogo-Jack S, Ismail-Beigi F, Korytkowski MT, Pratley RE, Schwartz GG, Kernan WN. Pioglitazone Prevents Diabetes in Insulin-Resistant Patients With Cerebrovascular Disease. Diabetes Care. PMID 27465265 DOI: 10.2337/Dc16-0798 |
0.397 |
|
| 2016 |
Kernan WN, Viscoli CM, Furie KL, Young LH, Inzucchi SE, Gorman M, Guarino PD, Lovejoy AM, Peduzzi PN, Conwit R, Brass LM, Schwartz GG, Adams HP, Berger L, Carolei A, et al. Pioglitazone after Ischemic Stroke or Transient Ischemic Attack. The New England Journal of Medicine. PMID 26886418 DOI: 10.1056/Nejmoa1506930 |
0.362 |
|
| 2015 |
Chyun DA, Wackers FJ, Inzucchi SE, Jose P, Weiss C, Davey JA, Heller GV, Iskandrian AE, Young LH. Autonomic dysfunction independently predicts poor cardiovascular outcomes in asymptomatic individuals with type 2 diabetes in the DIAD study. Sage Open Medicine. 3: 2050312114568476. PMID 26770763 DOI: 10.1177/2050312114568476 |
0.32 |
|
| 2015 |
Zaha VG, Qi D, Su KN, Palmeri M, Lee HY, Hu X, Wu X, Shulman GI, Rabinovitch PS, Russell R, Young LH. AMPK is critical for mitochondrial function during reperfusion after myocardial ischemia. Journal of Molecular and Cellular Cardiology. PMID 26746142 DOI: 10.1016/J.Yjmcc.2015.12.032 |
0.388 |
|
| 2015 |
Kim GE, Ross JL, Xie C, Su KN, Zaha VG, Wu X, Palmeri M, Ashraf M, Akar JG, Russell KS, Akar FG, Young LH. LKB1 deletion causes early changes in atrial channel expression and electrophysiology prior to atrial fibrillation. Cardiovascular Research. 108: 197-208. PMID 26378152 DOI: 10.1093/Cvr/Cvv212 |
0.304 |
|
| 2015 |
Qi D, Young LH. AMPK: energy sensor and survival mechanism in the ischemic heart. Trends in Endocrinology and Metabolism: Tem. PMID 26160707 DOI: 10.1016/J.Tem.2015.05.010 |
0.448 |
|
| 2015 |
Kim GE, Young LH. AMPK and the Atrial Response to Metabolic Inhibition. Journal of the American College of Cardiology. 66: 59-61. PMID 26139059 DOI: 10.1016/J.Jacc.2015.04.054 |
0.317 |
|
| 2014 |
Viscoli CM, Brass LM, Carolei A, Conwit R, Ford GA, Furie KL, Gorman M, Guarino PD, Inzucchi SE, Lovejoy AM, Parsons MW, Peduzzi PN, Ringleb PA, Schwartz GG, Spence JD, ... ... Young LH, et al. Pioglitazone for secondary prevention after ischemic stroke and transient ischemic attack: rationale and design of the Insulin Resistance Intervention after Stroke Trial. American Heart Journal. 168: 823-9.e6. PMID 25458644 DOI: 10.1016/J.Ahj.2014.07.016 |
0.353 |
|
| 2014 |
Qi D, Atsina K, Qu L, Hu X, Wu X, Xu B, Piecychna M, Leng L, Fingerle-Rowson G, Zhang J, Bucala R, Young LH. The vestigial enzyme D-dopachrome tautomerase protects the heart against ischemic injury. The Journal of Clinical Investigation. 124: 3540-50. PMID 24983315 DOI: 10.1172/Jci73061 |
0.407 |
|
| 2014 |
Kim GE, Ross JL, Xie C, Wu X, Palmeri M, Zaha VG, Ashraf M, Akar JG, Russell KS, Akar FG, Young LH. LKB1 is a Critical Regulator of Early Atrial Growth and Electrophysiological Function Biophysical Journal. 106: 304a. DOI: 10.1016/J.Bpj.2013.11.1764 |
0.329 |
|
| 2013 |
Li J, Qi D, Cheng H, Hu X, Miller EJ, Wu X, Russell KS, Mikush N, Zhang J, Xiao L, Sherwin RS, Young LH. Urocortin 2 autocrine/paracrine and pharmacologic effects to activate AMP-activated protein kinase in the heart. Proceedings of the National Academy of Sciences of the United States of America. 110: 16133-8. PMID 24043794 DOI: 10.1073/Pnas.1312775110 |
0.411 |
|
| 2013 |
Wang J, Tong C, Yan X, Yeung E, Gandavadi S, Hare AA, Du X, Chen Y, Xiong H, Ma C, Leng L, Young LH, Jorgensen WL, Li J, Bucala R. Limiting cardiac ischemic injury by pharmacological augmentation of macrophage migration inhibitory factor-AMP-activated protein kinase signal transduction. Circulation. 128: 225-36. PMID 23753877 DOI: 10.1161/Circulationaha.112.000862 |
0.426 |
|
| 2013 |
Jaba IM, Zhuang ZW, Li N, Jiang Y, Martin KA, Sinusas AJ, Papademetris X, Simons M, Sessa WC, Young LH, Tirziu D. NO triggers RGS4 degradation to coordinate angiogenesis and cardiomyocyte growth. The Journal of Clinical Investigation. 123: 1718-31. PMID 23454748 DOI: 10.1172/Jci65112 |
0.374 |
|
| 2013 |
Hage FG, Wackers FJ, Bansal S, Chyun DA, Young LH, Inzucchi SE, Iskandrian AE. The heart rate response to adenosine: a simple predictor of adverse cardiac outcomes in asymptomatic patients with type 2 diabetes. International Journal of Cardiology. 167: 2952-7. PMID 22981277 DOI: 10.1016/J.Ijcard.2012.08.011 |
0.402 |
|
| 2012 |
Zaha VG, Young LH. AMP-activated protein kinase regulation and biological actions in the heart. Circulation Research. 111: 800-14. PMID 22935535 DOI: 10.1161/Circresaha.111.255505 |
0.384 |
|
| 2012 |
Tandon S, Wackers FJ, Inzucchi SE, Bansal S, Staib LH, Chyun DA, Davey JA, Young LH. Gender-based divergence of cardiovascular outcomes in asymptomatic patients with type 2 diabetes: results from the DIAD study. Diabetes & Vascular Disease Research. 9: 124-30. PMID 22228772 DOI: 10.1177/1479164111431470 |
0.318 |
|
| 2012 |
Hage FG, Wackers FJT, Bansal S, Chyun DA, Young LH, Inzucchi S, Iskandrian AE. THE HEART RATE RESPONSE TO ADENOSINE AS A PREDICTOR OF ADVERSE CARDIAC OUTCOMES IN THE DETECTION OF ISCHEMIA IN ASYMPTOMATIC DIABETICS STUDY Journal of the American College of Cardiology. 59: E1162. DOI: 10.1016/S0735-1097(12)61163-2 |
0.404 |
|
| 2011 |
Kim AS, Miller EJ, Wright TM, Li J, Qi D, Atsina K, Zaha V, Sakamoto K, Young LH. A small molecule AMPK activator protects the heart against ischemia-reperfusion injury. Journal of Molecular and Cellular Cardiology. 51: 24-32. PMID 21402077 DOI: 10.1016/J.Yjmcc.2011.03.003 |
0.418 |
|
| 2011 |
Bansal S, Wackers FJ, Inzucchi SE, Chyun DA, Davey JA, Staib LH, Young LH. Five-year outcomes in high-risk participants in the Detection of Ischemia in Asymptomatic Diabetics (DIAD) study: a post hoc analysis. Diabetes Care. 34: 204-9. PMID 20929989 DOI: 10.2337/Dc10-1194 |
0.345 |
|
| 2011 |
Tandon S, Bansal S, Inzucchi SE, Staib LH, Davey JA, Chyun DA, Young LH, Wackers FJT. SCREENING ASYMPTOMATIC PATIENTS WITH TYPE 2 DIABETES FOR SILENT MYOCARDIAL ISCHEMIA: IMPORTANT GENDER DIFFERENCES FROM THE DETECTION OF ISCHEMIA IN ASYMPTOMATIC DIABETICS (DIAD) STUDY Journal of the American College of Cardiology. 57: E745. DOI: 10.1016/S0735-1097(11)60745-6 |
0.372 |
|
| 2010 |
Young LH. Risk stratification in diabetes: not all patients or perfusion defects are the same. Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology. 17: 990-2. PMID 21042899 DOI: 10.1007/S12350-010-9306-3 |
0.422 |
|
| 2010 |
Young LH. Diet-induced obesity obstructs insulin signaling in the heart. American Journal of Physiology. Heart and Circulatory Physiology. 298: H306-7. PMID 19940075 DOI: 10.1152/Ajpheart.01088.2009 |
0.312 |
|
| 2010 |
Bansal S, Wackers FJT, Inzucchi S, Young LH, Chyun DA. CARDIAC OUTCOMES AFTER SCREENING FOR ASYMPTOMATIC CORONARY ARTERY DISEASE IN PATIENTS WITH METABOLIC SYNDROME: POST-HOC ANALYSIS OF THE DIAD TRIAL Journal of the American College of Cardiology. 55: A141.E1325. DOI: 10.1016/S0735-1097(10)61326-5 |
0.315 |
|
| 2009 |
Qi D, Hu X, Wu X, Merk M, Leng L, Bucala R, Young LH. Cardiac macrophage migration inhibitory factor inhibits JNK pathway activation and injury during ischemia/reperfusion. The Journal of Clinical Investigation. 119: 3807-16. PMID 19920350 DOI: 10.1172/Jci39738 |
0.387 |
|
| 2009 |
Wackers FJ, Young LH. Lessons learned from the detection of ischemia in asymptomatic diabetics (DIAD) study. Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology. 16: 855-9. PMID 19685266 DOI: 10.1007/S12350-009-9138-1 |
0.3 |
|
| 2009 |
Young LH, Wackers FJ, Chyun DA, Davey JA, Barrett EJ, Taillefer R, Heller GV, Iskandrian AE, Wittlin SD, Filipchuk N, Ratner RE, Inzucchi SE. Cardiac outcomes after screening for asymptomatic coronary artery disease in patients with type 2 diabetes: the DIAD study: a randomized controlled trial. Jama. 301: 1547-55. PMID 19366774 DOI: 10.1001/Jama.2009.476 |
0.351 |
|
| 2009 |
Kernan WN, Viscoli CM, Demarco D, Mendes B, Shrauger K, Schindler JL, McVeety JC, Sicklick A, Moalli D, Greco P, Bravata DM, Eisen S, Resor L, Sena K, Story D, ... ... Young LH, et al. Boosting enrollment in neurology trials with Local Identification and Outreach Networks (LIONs). Neurology. 72: 1345-51. PMID 19365056 DOI: 10.1212/Wnl.0B013E3181A0Fda3 |
0.306 |
|
| 2009 |
Kim AS, Miller EJ, Young LH. AMP-activated protein kinase: a core signalling pathway in the heart. Acta Physiologica (Oxford, England). 196: 37-53. PMID 19239414 DOI: 10.1111/J.1748-1716.2009.01978.X |
0.428 |
|
| 2009 |
Wackers FJT, Young LH. Screening for asymptomatic coronary artery disease in patients with type 2 diabetes - Reply Jama - Journal of the American Medical Association. 302: 736-737. DOI: 10.1001/Jama.2009.1190 |
0.321 |
|
| 2008 |
Young LH. AMP-activated protein kinase conducts the ischemic stress response orchestra. Circulation. 117: 832-40. PMID 18268160 DOI: 10.1161/Circulationaha.107.713115 |
0.381 |
|
| 2008 |
Miller EJ, Li J, Leng L, McDonald C, Atsumi T, Bucala R, Young LH. Macrophage migration inhibitory factor stimulates AMP-activated protein kinase in the ischaemic heart. Nature. 451: 578-82. PMID 18235500 DOI: 10.1038/Nature06504 |
0.407 |
|
| 2007 |
Bax JJ, Young LH, Frye RL, Bonow RO, Steinberg HO, Barrett EJ. Screening for coronary artery disease in patients with diabetes. Diabetes Care. 30: 2729-36. PMID 17901530 DOI: 10.2337/Dc07-9927 |
0.365 |
|
| 2007 |
Wackers FJ, Chyun DA, Young LH, Heller GV, Iskandrian AE, Davey JA, Barrett EJ, Taillefer R, Wittlin SD, Filipchuk N, Ratner RE, Inzucchi SE. Resolution of asymptomatic myocardial ischemia in patients with type 2 diabetes in the Detection of Ischemia in Asymptomatic Diabetics (DIAD) study. Diabetes Care. 30: 2892-8. PMID 17682123 DOI: 10.2337/Dc07-1250 |
0.384 |
|
| 2007 |
Miller EJ, Li J, Sinusas KM, Holman GD, Young LH. Infusion of a biotinylated bis-glucose photolabel: a new method to quantify cell surface GLUT4 in the intact mouse heart. American Journal of Physiology. Endocrinology and Metabolism. 292: E1922-8. PMID 17341550 DOI: 10.1152/Ajpendo.00170.2006 |
0.356 |
|
| 2007 |
Reznick RM, Zong H, Li J, Morino K, Moore IK, Yu HJ, Liu ZX, Dong J, Mustard KJ, Hawley SA, Befroy D, Pypaert M, Hardie DG, Young LH, Shulman GI. Aging-associated reductions in AMP-activated protein kinase activity and mitochondrial biogenesis. Cell Metabolism. 5: 151-6. PMID 17276357 DOI: 10.1016/J.Cmet.2007.01.008 |
0.302 |
|
| 2006 |
Chyun DA, Young LH. Diabetes mellitus and cardiovascular disease. The Nursing Clinics of North America. 41: 681-95, viii-ix. PMID 17059982 DOI: 10.1016/J.Cnur.2006.07.007 |
0.384 |
|
| 2006 |
Papaioannou GI, Kasapis C, Seip RL, Grey NJ, Katten D, Wackers FJ, Inzucchi SE, Engel S, Taylor A, Young LH, Chyun DA, Davey JA, Iskandrian AE, Ratner RE, Robinson EC, et al. Value of peripheral vascular endothelial function in the detection of relative myocardial ischemia in asymptomatic type 2 diabetic patients who underwent myocardial perfusion imaging. Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology. 13: 362-8. PMID 16750781 DOI: 10.1016/J.Nuclcard.2006.01.022 |
0.371 |
|
| 2006 |
Li J, Coven DL, Miller EJ, Hu X, Young ME, Carling D, Sinusas AJ, Young LH. Activation of AMPK alpha- and gamma-isoform complexes in the intact ischemic rat heart. American Journal of Physiology. Heart and Circulatory Physiology. 291: H1927-34. PMID 16648175 DOI: 10.1152/Ajpheart.00251.2006 |
0.325 |
|
| 2005 |
Drexler AJ, Nesto RW, Abrahamson MJ, Bakris G, Bell D, Brunzell J, Dandona P, Davidson J, Fonseca V, Fowler M, Frye R, Giles T, Haffner S, Hollenberg N, Hsueh W, ... ... Young LH, et al. Evaluating the cardiovascular effects of the thiazolidinediones and their place in the management of type 2 diabetes in relation to the metabolic syndrome. Metabolic Syndrome and Related Disorders. 3: 147-73. PMID 18370723 DOI: 10.1089/Met.2005.3.147 |
0.322 |
|
| 2005 |
Li J, Miller EJ, Ninomiya-Tsuji J, Russell RR, Young LH. AMP-activated protein kinase activates p38 mitogen-activated protein kinase by increasing recruitment of p38 MAPK to TAB1 in the ischemic heart. Circulation Research. 97: 872-9. PMID 16179588 DOI: 10.1161/01.Res.0000187458.77026.10 |
0.389 |
|
| 2005 |
Young LH, Li J, Baron SJ, Russell RR. AMP-activated protein kinase: a key stress signaling pathway in the heart. Trends in Cardiovascular Medicine. 15: 110-8. PMID 16039971 DOI: 10.1016/J.Tcm.2005.04.005 |
0.422 |
|
| 2005 |
Baron SJ, Li J, Russell RR, Neumann D, Miller EJ, Tuerk R, Wallimann T, Hurley RL, Witters LA, Young LH. Dual mechanisms regulating AMPK kinase action in the ischemic heart. Circulation Research. 96: 337-45. PMID 15653571 DOI: 10.1161/01.Res.0000155723.53868.D2 |
0.369 |
|
| 2005 |
Wackers FJT, Young LH, Inzucchi SE, Chyun DA. Detection of Silent Myocardial Ischemia in Asymptomatic Diabetic Subjects Diabetes Care. 28: 232-233. DOI: 10.2337/Diacare.28.1.232 |
0.394 |
|
| 2005 |
Miller EJ, Russell RR, Li J, Young LH. AMPK - A pivotal rheostat in the control of cardiac metabolism Drug Discovery Today: Disease Mechanisms. 2: 93-100. DOI: 10.1016/J.Ddmec.2005.05.008 |
0.397 |
|
| 2004 |
Russell RR, Li J, Coven DL, Pypaert M, Zechner C, Palmeri M, Giordano FJ, Mu J, Birnbaum MJ, Young LH. AMP-activated protein kinase mediates ischemic glucose uptake and prevents postischemic cardiac dysfunction, apoptosis, and injury. The Journal of Clinical Investigation. 114: 495-503. PMID 15314686 DOI: 10.1172/Jci19297 |
0.453 |
|
| 2004 |
Wackers FJ, Young LH, Inzucchi SE, Chyun DA, Davey JA, Barrett EJ, Taillefer R, Wittlin SD, Heller GV, Filipchuk N, Engel S, Ratner RE, Iskandrian AE. Detection of silent myocardial ischemia in asymptomatic diabetic subjects: the DIAD study. Diabetes Care. 27: 1954-61. PMID 15277423 DOI: 10.2337/Diacare.27.8.1954 |
0.371 |
|
| 2004 |
Papaioannou GI, Seip RL, Grey NJ, Katten D, Taylor A, Inzucchi SE, Young LH, Chyun DA, Davey JA, Wackers FJ, Iskandrian AE, Ratner RE, Robinson EC, Carolan S, Engel S, et al. Brachial artery reactivity in asymptomatic patients with type 2 diabetes mellitus and microalbuminuria (from the Detection of Ischemia in Asymptomatic Diabetics-brachial artery reactivity study). The American Journal of Cardiology. 94: 294-9. PMID 15276091 DOI: 10.1016/J.Amjcard.2004.04.022 |
0.354 |
|
| 2004 |
Li J, Hu X, Selvakumar P, Russell RR, Cushman SW, Holman GD, Young LH. Role of the nitric oxide pathway in AMPK-mediated glucose uptake and GLUT4 translocation in heart muscle. American Journal of Physiology. Endocrinology and Metabolism. 287: E834-41. PMID 15265762 DOI: 10.1152/Ajpendo.00234.2004 |
0.354 |
|
| 2004 |
Huang Y, Hickey RP, Yeh JL, Liu D, Dadak A, Young LH, Johnson RS, Giordano FJ. Cardiac myocyte-specific HIF-1alpha deletion alters vascularization, energy availability, calcium flux, and contractility in the normoxic heart. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 1138-40. PMID 15132980 DOI: 10.1096/Fj.04-1510Fje |
0.361 |
|
| 2004 |
Johnson BF, Nesto RW, Pfeifer MA, Slater WR, Vinik AI, Chyun DA, Law G, Wackers FJ, Young LH. Cardiac abnormalities in diabetic patients with neuropathy: effects of aldose reductase inhibitor administration. Diabetes Care. 27: 448-54. PMID 14747227 DOI: 10.2337/Diacare.27.2.448 |
0.375 |
|
| 2004 |
Nesto RW, Bell D, Bonow RO, Fonseca V, Grundy SM, Horton ES, Le Winter M, Porte D, Semenkovich CF, Smith S, Young LH, Kahn R. Thiazolidinedione use, fluid retention, and congestive heart failure: a consensus statement from the American Heart Association and American Diabetes Association. Diabetes Care. 27: 256-63. PMID 14693998 DOI: 10.2337/Diacare.27.1.256 |
0.397 |
|
| 2004 |
Inzucchi SE, Young LH, Chyun DA, Wackers FJT. Screening for coronary artery disease in diabetic patients: The DIAD study The British Journal of Diabetes & Vascular Disease. 4: 317-319. DOI: 10.1177/14746514040040050501 |
0.412 |
|
| 2003 |
Young LH. Insulin resistance and the effects of thiazolidinediones on cardiac metabolism. The American Journal of Medicine. 115: 75S-80S. PMID 14678870 DOI: 10.1016/J.Amjmed.2003.09.013 |
0.428 |
|
| 2003 |
Nesto RW, Bell D, Bonow RO, Fonseca V, Grundy SM, Horton ES, Le Winter M, Porte D, Semenkovich CF, Smith S, Young LH, Kahn R. Thiazolidinedione use, fluid retention, and congestive heart failure: a consensus statement from the American Heart Association and American Diabetes Association. October 7, 2003. Circulation. 108: 2941-8. PMID 14662691 DOI: 10.1161/01.Cir.0000103683.99399.7E |
0.397 |
|
| 2003 |
Coven DL, Hu X, Cong L, Bergeron R, Shulman GI, Hardie DG, Young LH. Physiological role of AMP-activated protein kinase in the heart: graded activation during exercise. American Journal of Physiology. Endocrinology and Metabolism. 285: E629-36. PMID 12759223 DOI: 10.1152/Ajpendo.00171.2003 |
0.329 |
|
| 2003 |
Young LH, Jose P, Chyun D. Diagnosis of CAD in patients with diabetes: who to evaluate. Current Diabetes Reports. 3: 19-27. PMID 12643142 DOI: 10.1007/S11892-003-0048-3 |
0.385 |
|
| 2003 |
Wackers FJ, Young LH, Inzucchi SE, Chyun DA, Davey JA. Detection of ischemia in asymptomatic diabetics: Preliminary results of the DIAD study Journal of the American College of Cardiology. 41: 409. DOI: 10.1016/S0735-1097(03)81197-X |
0.337 |
|
| 2002 |
Chyun D, Vaccarino V, Murillo J, Young LH, Krumholz HM. Acute myocardial infarction in the elderly with diabetes. Heart & Lung : the Journal of Critical Care. 31: 327-39. PMID 12487011 DOI: 10.1067/Mhl.2002.126049 |
0.402 |
|
| 2002 |
Chyun D, Vaccarino V, Murillo J, Young LH, Krumholz HM. Cardiac Outcomes After Myocardial Infarction in Elderly Patients With Diabetes Mellitus American Journal of Critical Care. 11: 504-519. DOI: 10.4037/Ajcc2002.11.6.504 |
0.44 |
|
| 2001 |
Russell RR, Chyun D, Song S, Sherwin RS, Tamborlane WV, Lee FA, Pfeifer MA, Rife F, Wackers FJ, Young LH. Cardiac responses to insulin-induced hypoglycemia in nondiabetic and intensively treated type 1 diabetic patients. American Journal of Physiology. Endocrinology and Metabolism. 281: E1029-36. PMID 11595660 DOI: 10.1152/Ajpendo.2001.281.5.E1029 |
0.394 |
|
| 2001 |
Bergeron R, Previs SF, Cline GW, Perret P, Russell RR, Young LH, Shulman GI. Effect of 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside infusion on in vivo glucose and lipid metabolism in lean and obese Zucker rats. Diabetes. 50: 1076-82. PMID 11334411 DOI: 10.2337/Diabetes.50.5.1076 |
0.343 |
|
| 2001 |
Young L, Russell R, Coven D, Shulman G, Sinusas A. Activation of glucose transport in the ischemic heart: Translocation of GLUT4 and GLUT1 by 5′-AMP-activated protein kinase Journal of Molecular and Cellular Cardiology. 33: A145. DOI: 10.1016/S0022-2828(01)90556-5 |
0.379 |
|
| 2000 |
McNulty PH, Jacob R, Deckelbaum LI, Young LH. Effect of hyperinsulinemia on myocardial amino acid uptake in patients with coronary artery disease. Metabolism: Clinical and Experimental. 49: 1365-9. PMID 11079831 DOI: 10.1053/Meta.2000.9510 |
0.4 |
|
| 2000 |
Young LH, Coven DL, Russell RR. Cellular and molecular regulation of cardiac glucose transport. Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology. 7: 267-76. PMID 10888399 DOI: 10.1016/S1071-3581(00)70016-X |
0.349 |
|
| 1999 |
Young LH, Russell RR, Yin R, Caplan MJ, Ren J, Bergeron R, Shulman GI, Sinusas AJ. Regulation of myocardial glucose uptake and transport during ischemia and energetic stress. The American Journal of Cardiology. 83: 25H-30H. PMID 10750583 DOI: 10.1016/S0002-9149(99)00253-2 |
0.405 |
|
| 1999 |
Russell RR, Bergeron R, Shulman GI, Young LH. Translocation of myocardial GLUT-4 and increased glucose uptake through activation of AMPK by AICAR. The American Journal of Physiology. 277: H643-9. PMID 10444490 DOI: 10.1152/Ajpheart.1999.277.2.H643 |
0.391 |
|
| 1999 |
Bergeron R, Russell RR, Young LH, Ren JM, Marcucci M, Lee A, Shulman GI. Effect of AMPK activation on muscle glucose metabolism in conscious rats. The American Journal of Physiology. 276: E938-44. PMID 10329989 DOI: 10.1152/Ajpendo.1999.276.5.E938 |
0.344 |
|
| 1999 |
Young LH, Renfu Y, Hu X, Chong S, Hasan S, Jacob R, Sherwin RS. Insulin-like growth factor I stimulates cardiac myosin heavy chain and actin synthesis in the awake rat. The American Journal of Physiology. 276: E143-50. PMID 9886960 DOI: 10.1152/Ajpendo.1999.276.1.E143 |
0.335 |
|
| 1998 |
Russell RR, Yin R, Caplan MJ, Hu X, Ren J, Shulman GI, Sinusas AJ, Young LH. Additive effects of hyperinsulinemia and ischemia on myocardial GLUT1 and GLUT4 translocation in vivo. Circulation. 98: 2180-6. PMID 9815873 DOI: 10.1161/01.Cir.98.20.2180 |
0.362 |
|
| 1997 |
Young LH, Renfu Y, Russell R, Hu X, Caplan M, Ren J, Shulman GI, Sinusas AJ. Low-flow ischemia leads to translocation of canine heart GLUT-4 and GLUT-1 glucose transporters to the sarcolemma in vivo. Circulation. 95: 415-22. PMID 9008459 DOI: 10.1161/01.Cir.95.2.415 |
0.364 |
|
| 1996 |
Jacob R, Hu X, Niederstock D, Hasan S, McNulty PH, Sherwin RS, Young LH. IGF-I stimulation of muscle protein synthesis in the awake rat: permissive role of insulin and amino acids. The American Journal of Physiology. 270: E60-6. PMID 8772474 DOI: 10.1152/Ajpendo.1996.270.1.E60 |
0.317 |
|
| 1995 |
McNulty PH, Louard RJ, Deckelbaum LI, Zaret BL, Young LH. Hyperinsulinemia inhibits myocardial protein degradation in patients with cardiovascular disease and insulin resistance. Circulation. 92: 2151-6. PMID 7554195 DOI: 10.1161/01.Cir.92.8.2151 |
0.42 |
|
| 1994 |
Young LH, Stirewalt W, McNulty PH, Revkin JH, Barrett EJ. Effect of insulin on rat heart and skeletal muscle phenylalanyl-tRNA labeling and protein synthesis in vivo. The American Journal of Physiology. 267: E337-42. PMID 8074214 DOI: 10.1152/Ajpendo.1994.267.2.E337 |
0.34 |
|
| 1993 |
McNulty PH, Young LH, Barrett EJ. Response of rat heart and skeletal muscle protein in vivo to insulin and amino acid infusion. The American Journal of Physiology. 264: E958-65. PMID 8333520 DOI: 10.1152/Ajpendo.1993.264.6.E958 |
0.319 |
|
| 1992 |
Young LH, Dahl DM, Rauner D, Barrett EJ. Physiological hyperinsulinemia inhibits myocardial protein degradation in vivo in the canine heart. Circulation Research. 71: 393-400. PMID 1628395 DOI: 10.1161/01.Res.71.2.393 |
0.37 |
|
| 1992 |
YOUNG L. Physiologic hyperinsulinemia inhibits canine myocardial protein degradation in vivo Journal of Molecular and Cellular Cardiology. 24: S26. DOI: 10.1016/0022-2828(92)92934-5 |
0.322 |
|
| 1991 |
Young LH, McNulty PH, Morgan C, Deckelbaum LI, Zaret BL, Barrett EJ. Myocardial protein turnover in patients with coronary artery disease. Effect of branched chain amino acid infusion. The Journal of Clinical Investigation. 87: 554-60. PMID 1991838 DOI: 10.1172/Jci115030 |
0.4 |
|
| 1990 |
Young LH, Jaffe CC, Revkin JH, McNulty PH, Cleman M. Metabolic and functional effects of perfluorocarbon distal perfusion during coronary angioplasty. The American Journal of Cardiology. 65: 986-90. PMID 2327360 DOI: 10.1016/0002-9149(90)91001-M |
0.367 |
|
| 1990 |
Revkin JH, Young LH, Stirewalt WS, Dahl DM, Gelfand RA, Zaret BL, Barrett EJ. In vivo measurement of myocardial protein turnover using an indicator dilution technique. Circulation Research. 67: 902-12. PMID 2208613 DOI: 10.1161/01.Res.67.4.902 |
0.368 |
|
| 1989 |
Young LH, Zaret BL, Barrett EJ. Physiologic hyperinsulinemia stimulates lactate extraction by heart muscle in the conscious dog. Metabolism: Clinical and Experimental. 38: 1115-9. PMID 2682138 DOI: 10.1016/0026-0495(89)90049-8 |
0.375 |
|
| 1988 |
Barrett EJ, Schwartz RG, Young LH, Jacob R, Zaret BL. Effect of chronic diabetes on myocardial fuel metabolism and insulin sensitivity. Diabetes. 37: 943-8. PMID 3290011 DOI: 10.2337/Diab.37.7.943 |
0.405 |
|
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