Nikolaus S. Trede - Publications

Oncological Sciences University of Utah, Salt Lake City, UT 
Molecular Biology, Biochemistry, Pharmacology, Immunology, Oncology

45 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Oftedal BE, Maio S, Handel AE, White MPJ, Howie D, Davis S, Prevot N, Rota IA, Deadman ME, Kessler BM, Fischer R, Trede NS, Sezgin E, Maizels RM, Holländer GA. The chaperonin CCT8 controls proteostasis essential for T cell maturation, selection, and function. Communications Biology. 4: 681. PMID 34083746 DOI: 10.1038/s42003-021-02203-0  0.428
2018 Torre M, Solomon IH, Sutherland CL, Nikiforow S, DeAngelo DJ, Stone RM, Vaitkevicius H, Galinsky IA, Padera RF, Trede N, Santagata S. Neuropathology of a Case With Fatal CAR T-Cell-Associated Cerebral Edema. Journal of Neuropathology and Experimental Neurology. PMID 30060228 DOI: 10.1093/Jnen/Nly064  0.514
2018 Olson NE, Ragan SP, Ponko S, Trede NS, Stern HM, Sutherland CL. Tumor gene signature associated with neurotoxicity in R/R B-ALL patients treated with JCAR015, a CD19-directed CAR T cell product. Journal of Clinical Oncology. 36: 7007-7007. DOI: 10.1200/Jco.2018.36.15_Suppl.7007  0.422
2015 Murayama E, Sarris M, Redd M, Le Guyader D, Vivier C, Horsley W, Trede N, Herbomel P. NACA deficiency reveals the crucial role of somite-derived stromal cells in haematopoietic niche formation. Nature Communications. 6: 8375. PMID 26411530 DOI: 10.1038/Ncomms9375  0.374
2015 Niesvizky R, Richardson PG, Gabrail NY, Madan S, Yee AJ, Quayle SN, Almeciga-Pinto I, Jones SS, Houston L, Hayes D, Van Duzer J, Wheeler C, Trede NS, Raje NS. ACY-241, a Novel, HDAC6 Selective Inhibitor: Synergy with Immunomodulatory (IMiD®) Drugs in Multiple Myeloma (MM) Cells and Early Clinical Results (ACE-MM-200 Study) Blood. 126: 3040-3040. DOI: 10.1182/Blood.V126.23.3040.3040  0.328
2014 Cusick MF, Libbey JE, Trede NS, Fujinami RS. Targeting insulin-like growth factor 1 leads to amelioration of inflammatory demyelinating disease. Plos One. 9: e94486. PMID 24718491 DOI: 10.1371/Journal.Pone.0094486  0.469
2013 Choudhry P, Trede NS. DiGeorge syndrome gene tbx1 functions through wnt11r to regulate heart looping and differentiation. Plos One. 8: e58145. PMID 23533583 DOI: 10.1371/Journal.Pone.0058145  0.711
2013 Trede NS, Heaton W, Ridges S, Sofla H, Cusick M, Bearss D, Jones D, Fujinami RS. Discovery of biologically active oncologic and immunologic small molecule therapies using zebrafish: overview and example of modulation of T cell activation. Current Protocols in Pharmacology / Editorial Board, S.J. Enna (Editor-in-Chief) ... [Et Al.]. Unit14.24. PMID 23456612 DOI: 10.1002/0471141755.Ph1424S60  0.752
2012 Frazer JK, Batchelor LA, Bradley DF, Brown KH, Dobrinski KP, Lee C, Trede NS. Genomic amplification of an endogenous retrovirus in zebrafish T-cell malignancies. Advances in Hematology. 2012: 627920. PMID 22745640 DOI: 10.1155/2012/627920  0.527
2012 Hutchinson SA, Tooke-Locke E, Wang J, Tsai S, Katz T, Trede NS. Tbl3 regulates cell cycle length during zebrafish development. Developmental Biology. 368: 261-72. PMID 22659140 DOI: 10.1016/J.Ydbio.2012.05.024  0.428
2012 Blackburn JS, Liu S, Raiser DM, Martinez SA, Feng H, Meeker ND, Gentry J, Neuberg D, Look AT, Ramaswamy S, Bernards A, Trede NS, Langenau DM. Notch signaling expands a pre-malignant pool of T-cell acute lymphoblastic leukemia clones without affecting leukemia-propagating cell frequency. Leukemia. 26: 2069-78. PMID 22538478 DOI: 10.1038/Leu.2012.116  0.582
2012 Ridges S, Heaton WL, Joshi D, Choi H, Eiring A, Batchelor L, Choudhry P, Manos EJ, Sofla H, Sanati A, Welborn S, Agarwal A, Spangrude GJ, Miles RR, Cox JE, ... ... Trede NS, et al. Zebrafish screen identifies novel compound with selective toxicity against leukemia. Blood. 119: 5621-31. PMID 22490804 DOI: 10.1182/Blood-2011-12-398818  0.719
2012 Cusick MF, Libbey JE, Trede NS, Eckels DD, Fujinami RS. Human T cell expansion and experimental autoimmune encephalomyelitis inhibited by Lenaldekar, a small molecule discovered in a zebrafish screen. Journal of Neuroimmunology. 244: 35-44. PMID 22245285 DOI: 10.1016/J.Jneuroim.2011.12.024  0.583
2012 Renshaw SA, Trede NS. A model 450 million years in the making: zebrafish and vertebrate immunity. Disease Models & Mechanisms. 5: 38-47. PMID 22228790 DOI: 10.1242/Dmm.007138  0.31
2012 Frazer JK, Batchelor LA, Bradley DF, Brown KH, Dobrinski KP, Lee C, Trede NS. Genomic amplification of an endogenous retrovirus in zebrafish T-cell malignancies Advances in Hematology. 2012. DOI: 10.1155/2012/627920  0.422
2011 Rudner LA, Brown KH, Dobrinski KP, Bradley DF, Garcia MI, Smith ACH, Downie JM, Meeker ND, Look AT, Downing JR, Gutierrez A, Mullighan CG, Schiffman JD, Lee C, Trede NS, et al. Shared acquired genomic changes in zebrafish and human T-ALL Oncogene. 30: 4289-4296. PMID 21552289 DOI: 10.1038/Onc.2011.138  0.757
2011 Choudhry P, Joshi D, Funke B, Trede N. Alcama mediates Edn1 signaling during zebrafish cartilage morphogenesis. Developmental Biology. 349: 483-93. PMID 21073867 DOI: 10.1016/J.Ydbio.2010.11.006  0.728
2011 Mangum DS, Shams S, Downie JM, von Schwedler U, Rodic V, Engel M, Barnette P, Frazer JK, Trede N, Pei D, Cheng C, Pui C, Hunger SP, Yang JJ, Miles RR, et al. Focal 22q11.22 Loss Combined with IKZF1 Alterations Predict Very Poor Outcome in Childhood Acute Lymphoblastic Leukemia Blood. 118: 741-741. DOI: 10.1182/Blood.V118.21.741.741  0.301
2010 Mione MC, Trede NS. The zebrafish as a model for cancer. Disease Models & Mechanisms. 3: 517-23. PMID 20354112 DOI: 10.1242/Dmm.004747  0.35
2010 Meeker ND, Smith ACH, Frazer JK, Bradley DF, Rudner LA, Love C, Trede NS. Characterization of the zebrafish T cell receptor β locus Immunogenetics. 62: 23-29. PMID 20054533 DOI: 10.1007/S00251-009-0407-6  0.746
2010 Downie J, Barnette P, Rodic V, Frazer JK, Trede N, Devidas M, Mullighan C, Hunger S, Miles RR, Schiffman JD. T-Cell Receptor Gene Deletions Are Associated with High Risk Features and Worse Outcome In Childhood Precursor B-Cell Acute Lymphoblastic Leukemia (ALL) Blood. 116: 275-275. DOI: 10.1182/Blood.V116.21.275.275  0.381
2010 Miles RR, Downie J, Jahromi MS, Joshi D, Rodic V, Muschen M, Yang JJ, Evans WE, Meeker N, Trede N, Frazer JK, Barnette P, Schiffman JD. VPREB1 Deletions Occur Independent of Lambda-Light Chain Rearrangement and Predict Worse Outcome In Pediatric Acute Lymphoblastic Leukemia (ALL) Blood. 116: 273-273. DOI: 10.1182/Blood.V116.21.273.273  0.375
2010 Trede N, Ridges S, Joshi D, Beck J, Soffla H, Balan K, Manos B, Davis A, Sweeney N, Meeker N, Frazer JK, Agarwal A, Johnson R, Matei I, Montpellier B, et al. A Drug Screen in Zebrafish Identifies a New Therapeutic Agent Active in Acute Lymphoblastic Leukemia Blood. 116: 2129-2129. DOI: 10.1182/Blood.V116.21.2129.2129  0.767
2010 Rudner LA, Brown KH, Dobrinski KP, Bradley DF, Downie J, Meeker ND, Smith A, Garcia MI, Gutierrez A, Mullighan C, Look AT, Downing JR, Schiffman JD, Lee C, Trede N, et al. Cross-Species Comparison of Acquired Genetic Changes In T Cell Malignancy. Blood. 116: 1192-1192. DOI: 10.1182/Blood.V116.21.1192.1192  0.566
2009 Mione M, Meijer AH, Snaar-Jagalska BE, Spaink HP, Trede NS. Disease modeling in zebrafish: cancer and immune responses--a report on a workshop held in Spoleto, Italy, July 20-22, 2009. Zebrafish. 6: 445-51. PMID 20047471 DOI: 10.1089/Zeb.2009.0638  0.457
2009 Amigo JD, Ackermann GE, Cope JJ, Yu M, Cooney JD, Ma D, Langer NB, Shafizadeh E, Shaw GC, Horsely W, Trede NS, Davidson AJ, Barut BA, Zhou Y, Wojiski SA, et al. The role and regulation of friend of GATA-1 (FOG-1) during blood development in the zebrafish. Blood. 114: 4654-63. PMID 19729519 DOI: 10.1182/Blood-2008-12-189910  0.401
2009 Frazer JK, Meeker ND, Rudner L, Bradley DF, Smith AC, Demarest B, Joshi D, Locke EE, Hutchinson SA, Tripp S, Perkins SL, Trede NS. Heritable T-cell malignancy models established in a zebrafish phenotypic screen. Leukemia. 23: 1825-35. PMID 19516274 DOI: 10.1038/Leu.2009.116  0.62
2009 Jima DD, Shah RN, Orcutt TM, Joshi D, Law JM, Litman GW, Trede NS, Yoder JA. Enhanced transcription of complement and coagulation genes in the absence of adaptive immunity. Molecular Immunology. 46: 1505-16. PMID 19200601 DOI: 10.1016/J.Molimm.2008.12.021  0.303
2008 Trede NS, Ota T, Kawasaki H, Paw BH, Katz T, Demarest B, Hutchinson S, Zhou Y, Hersey C, Zapata A, Amemiya CT, Zon LI. Zebrafish mutants with disrupted early T-cell and thymus development identified in early pressure screen. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 237: 2575-84. PMID 18729230 DOI: 10.1002/Dvdy.21683  0.566
2008 Meeker ND, Trede NS. Immunology and zebrafish: spawning new models of human disease. Developmental and Comparative Immunology. 32: 745-57. PMID 18222541 DOI: 10.1016/J.Dci.2007.11.011  0.333
2008 Saltis M, Criscitiello MF, Ohta Y, Keefe M, Trede NS, Goitsuka R, Flajnik MF. Evolutionarily conserved and divergent regions of the autoimmune regulator (Aire) gene: a comparative analysis. Immunogenetics. 60: 105-14. PMID 18214467 DOI: 10.1007/S00251-007-0268-9  0.49
2008 Frazer JK, Meeker N, Bradley DF, Rudner L, Perkins SL, Trede N. Three Heritable T Cell Malignancy Models Established Using a Forward Genetic Mutagenesis Screen in Zebrafish. Blood. 112: 2052-2052. DOI: 10.1182/Blood.V112.11.2052.2052  0.627
2007 Trede NS, Medenbach J, Damianov A, Hung LH, Weber GJ, Paw BH, Zhou Y, Hersey C, Zapata A, Keefe M, Barut BA, Stuart AB, Katz T, Amemiya CT, Zon LI, et al. Network of coregulated spliceosome components revealed by zebrafish mutant in recycling factor p110. Proceedings of the National Academy of Sciences of the United States of America. 104: 6608-13. PMID 17416673 DOI: 10.1073/Pnas.0701919104  0.3
2005 Bahary N, Davidson A, Ransom D, Shepard J, Stern H, Trede N, Zhou Y, Barut B, Zon LI. The Zon laboratory guide to positional cloning in zebrafish. Methods in Cell Biology. 77: 305-29. PMID 15602919 DOI: 10.1016/S0091-679X(04)77017-X  0.301
2004 Ransom DG, Bahary N, Niss K, Traver D, Burns C, Trede NS, Paffett-Lugassy N, Saganic WJ, Lim CA, Hersey C, Zhou Y, Barut BA, Lin S, Kingsley PD, Palis J, et al. The zebrafish moonshine gene encodes transcriptional intermediary factor 1gamma, an essential regulator of hematopoiesis. Plos Biology. 2: E237. PMID 15314655 DOI: 10.1371/Journal.Pbio.0020237  0.388
2004 Langenau DM, Ferrando AA, Traver D, Kutok JL, Hezel JP, Kanki JP, Zon LI, Look AT, Trede NS. In vivo tracking of T cell development, ablation, and engraftment in transgenic zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 101: 7369-74. PMID 15123839 DOI: 10.1073/Pnas.0402248101  0.551
2004 Altmann SM, Mellon MT, Johnson MC, Paw BH, Trede NS, Zon LI, Kim CH. Cloning and characterization of an Mx gene and its corresponding promoter from the zebrafish, Danio rerio. Developmental and Comparative Immunology. 28: 295-306. PMID 14698216 DOI: 10.1016/J.Dci.2003.09.001  0.307
2003 Traver D, Herbomel P, Patton EE, Murphey RD, Yoder JA, Litman GW, Catic A, Amemiya CT, Zon LI, Trede NS. The zebrafish as a model organism to study development of the immune system. Advances in Immunology. 81: 253-330. PMID 14711058 DOI: 10.1016/S0065-2776(03)81007-6  0.429
2003 Paw BH, Davidson AJ, Zhou Y, Li R, Pratt SJ, Lee C, Trede NS, Brownlie A, Donovan A, Liao EC, Ziai JM, Drejer AH, Guo W, Kim CH, Gwynn B, et al. Cell-specific mitotic defect and dyserythropoiesis associated with erythroid band 3 deficiency. Nature Genetics. 34: 59-64. PMID 12669066 DOI: 10.1038/Ng1137  0.377
2003 Langenau DM, Traver D, Ferrando AA, Kutok JL, Aster JC, Kanki JP, Lin S, Prochownik E, Trede NS, Zon LI, Look AT. Myc-induced T cell leukemia in transgenic zebrafish. Science (New York, N.Y.). 299: 887-90. PMID 12574629 DOI: 10.1126/Science.1080280  0.512
2001 Trede NS, Zapata A, Zon LI. Fishing for lymphoid genes. Trends in Immunology. 22: 302-7. PMID 11377288 DOI: 10.1016/S1471-4906(01)01939-1  0.514
1998 Trede NS, Zon LI. Development of T-cells during fish embryogenesis. Developmental and Comparative Immunology. 22: 253-63. PMID 9700456 DOI: 10.1016/S0145-305X(98)00009-3  0.542
1994 Fuleihan R, Trede N, Chatila T, Geha RS. Superantigens activate HIV-1 gene expression in monocytic cells. Clinical Immunology and Immunopathology. 72: 357-61. PMID 8062448 DOI: 10.1006/Clin.1994.1153  0.322
1993 Trede NS, Chatila T, Geha RS. Activator protein-1 (AP-1) is stimulated by microbial superantigens in human monocytic cells. European Journal of Immunology. 23: 2129-35. PMID 8370396 DOI: 10.1002/Eji.1830230913  0.3
1992 Chatila T, Scholl P, Spertini F, Ramesh N, Trede N, Fuleihan R, Geha RS. Toxic shock syndrome toxin-1, toxic shock, and the immune system. Current Topics in Microbiology and Immunology. 174: 63-79. PMID 1802619 DOI: 10.1007/978-3-642-50998-8_5  0.429
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