Susan S. Smyth - Publications

Affiliations: 
Physiology University of Kentucky, Lexington, KY 
Area:
Biochemistry, Physiology Biology

82 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Mueller PA, Yang L, Ubele M, Mao G, Brandon J, Vandra J, Nichols TC, Escalante-Alcalde D, Morris AJ, Smyth SS. Coronary Artery Disease Risk-Associated Gene and Its Product Lipid Phosphate Phosphatase 3 Regulate Experimental Atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA119313056. PMID 31533471 DOI: 10.1161/ATVBAHA.119.313056  0.56
2019 Kraemer M, Mao G, Hammill C, Yan B, Li Y, Onono F, Smyth SS, Morris AJ. Effects of diet and hyperlipidemia on levels and distribution of circulating lysophosphatidic acid. Journal of Lipid Research. PMID 31484695 DOI: 10.1194/jlr.M093096  0.56
2019 Mao G, Smyth SS, Morris AJ. Regulation of PLPP3 gene expression by NF-kB family transcription factors. The Journal of Biological Chemistry. PMID 31362988 DOI: 10.1074/jbc.RA119.009002  0.56
2019 Wu C, Lu W, Zhang Y, Zhang G, Shi X, Hisada Y, Grover SP, Zhang X, Li L, Xiang B, Shi J, Li XA, Daugherty A, Smyth SS, Kirchhofer D, et al. Inflammasome Activation Triggers Blood Clotting and Host Death through Pyroptosis. Immunity. PMID 31076358 DOI: 10.1016/j.immuni.2019.04.003  0.32
2019 Yang L, Kraemer M, Fang XF, Angel PM, Drake RR, Morris AJ, Smyth SS. LPA Receptor 4 deficiency attenuates experimental atherosclerosis. Journal of Lipid Research. PMID 30796085 DOI: 10.1194/jlr.M091066  0.56
2019 Brandon JA, Kraemer M, Vandra J, Halder S, Ubele M, Morris AJ, Smyth SS. Adipose-derived autotaxin regulates inflammation and steatosis associated with diet-induced obesity. Plos One. 14: e0208099. PMID 30730895 DOI: 10.1371/journal.pone.0208099  0.56
2018 Federico L, Yang L, Brandon J, Panchatcharam M, Ren H, Mueller P, Sunkara M, Escalante-Alcalde D, Morris AJ, Smyth SS. Lipid phosphate phosphatase 3 regulates adipocyte sphingolipid synthesis, but not developmental adipogenesis or diet-induced obesity in mice. Plos One. 13: e0198063. PMID 29889835 DOI: 10.1371/journal.pone.0198063  0.56
2017 Dong A, Mueller P, Yang F, Yang L, Morris A, Smyth SS. Direct thrombin inhibition with dabigatran attenuates pressure overload-induced cardiac fibrosis and dysfunction in mice. Thrombosis Research. 159: 58-64. PMID 28982031 DOI: 10.1016/j.thromres.2017.09.016  0.32
2017 Kraemer MP, Halder S, Smyth SS, Morris AJ. Measurement of Lysophosphatidic Acid and Sphingosine-1-Phosphate by Liquid Chromatography-Coupled Electrospray Ionization Tandem Mass Spectrometry. Methods in Molecular Biology (Clifton, N.J.). PMID 28770493 DOI: 10.1007/7651_2017_55  0.56
2016 Morris AJ, Smyth SS. Regulation of Lysophosphatidic Acid Metabolism and Signaling by Lipoproteins. Arteriosclerosis, Thrombosis, and Vascular Biology. 36: 2029-30. PMID 27655776 DOI: 10.1161/ATVBAHA.116.308237  0.56
2016 Sexton TR, Wallace EL, Chen A, Charnigo RJ, Reda HK, Ziada KM, Gurley JC, Smyth SS. Thromboinflammatory response and predictors of outcomes in patients undergoing transcatheter aortic valve replacement. Journal of Thrombosis and Thrombolysis. PMID 26743061 DOI: 10.1007/s11239-015-1326-z  0.32
2015 Xiang B, Zhang G, Ye S, Zhang R, Huang C, Liu J, Tao M, Ruan C, Smyth SS, Whiteheart SW, Li Z. Characterization of a Novel Integrin Binding Protein, VPS33B, Which Is Important for Platelet Activation and In Vivo Thrombosis and Hemostasis. Circulation. 132: 2334-44. PMID 26399659 DOI: 10.1161/CIRCULATIONAHA.115.018361  0.32
2015 Klyachkin YM, Nagareddy PR, Ye S, Wysoczynski M, Asfour A, Gao E, Sunkara M, Brandon JA, Annabathula R, Ponnapureddy R, Solanki M, Pervaiz ZH, Smyth SS, Ratajczak MZ, Morris AJ, et al. Pharmacological Elevation of Circulating Bioactive Phosphosphingolipids Enhances Myocardial Recovery After Acute Infarction. Stem Cells Translational Medicine. PMID 26371341 DOI: 10.5966/sctm.2014-0273  0.56
2015 Abdel-Latif A, Heron PM, Morris AJ, Smyth SS. Lysophospholipids in coronary artery and chronic ischemic heart disease. Current Opinion in Lipidology. PMID 26270808 DOI: 10.1097/MOL.0000000000000226  0.56
2015 Reschen ME, Gaulton KJ, Lin D, Soilleux EJ, Morris AJ, Smyth SS, O'Callaghan CA. Lipid-induced epigenomic changes in human macrophages identify a coronary artery disease-associated variant that regulates PPAP2B Expression through Altered C/EBP-beta binding. Plos Genetics. 11: e1005061. PMID 25835000 DOI: 10.1371/journal.pgen.1005061  0.32
2015 George B, Wallace EL, Charnigo R, Wingerter KE, Kapadia P, Gurley JC, Smyth SS. A retrospective analysis of catheter-based thrombolytic therapy for acute submassive and massive pulmonary embolism. Vascular Medicine (London, England). 20: 122-30. PMID 25832600 DOI: 10.1177/1358863X14568135  0.32
2015 Sexton TR, Wallace EL, Macaulay TE, Charnigo RJ, Evangelista V, Campbell CL, Bailey AL, Smyth SS. The effect of rosuvastatin on platelet-leukocyte interactions in the setting of acute coronary syndrome. Journal of the American College of Cardiology. 65: 306-7. PMID 25614429 DOI: 10.1016/j.jacc.2014.10.047  0.32
2015 Ferraris VA, Boral LI, Cohen AJ, Smyth SS, White GC. Consensus review of the treatment of cardiovascular disease in people with hemophilia A and B. Cardiology in Review. 23: 53-68. PMID 25436468 DOI: 10.1097/CRD.0000000000000045  0.32
2015 Sexton TR, Wallace EL, Macaulay TE, Charnigo RJ, Evangelista V, Campbell CL, Bailey AL, Smyth SS. The effect of rosuvastatin on thromboinflammation in the setting of acute coronary syndrome. Journal of Thrombosis and Thrombolysis. 39: 186-95. PMID 25307674 DOI: 10.1007/s11239-014-1142-x  0.32
2014 Morris AJ, Smyth SS. Lipid phosphate phosphatases: more than one way to put the brakes on LPA signaling? Journal of Lipid Research. 55: 2195-7. PMID 25271297 DOI: 10.1194/jlr.C054957  0.56
2014 Ye S, Huang Y, Joshi S, Zhang J, Yang F, Zhang G, Smyth SS, Li Z, Takai Y, Whiteheart SW. Platelet secretion and hemostasis require syntaxin-binding protein STXBP5. The Journal of Clinical Investigation. 124: 4517-28. PMID 25244094 DOI: 10.1172/JCI75572  0.32
2014 Yang F, Dong A, Ahamed J, Sunkara M, Smyth SS. Granule cargo release from bone marrow-derived cells sustains cardiac hypertrophy. American Journal of Physiology. Heart and Circulatory Physiology. 307: H1529-38. PMID 25239803 DOI: 10.1152/ajpheart.00951.2013  0.32
2014 Totani L, Piccoli A, Dell'Elba G, Concetta A, Di Santo A, Martelli N, Federico L, Pamuklar Z, Smyth SS, Evangelista V. Phosphodiesterase type 4 blockade prevents platelet-mediated neutrophil recruitment at the site of vascular injury. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 1689-96. PMID 24925970 DOI: 10.1161/ATVBAHA.114.303939  0.32
2014 Nagareddy PR, Kraakman M, Masters SL, Stirzaker RA, Gorman DJ, Grant RW, Dragoljevic D, Hong ES, Abdel-Latif A, Smyth SS, Choi SH, Korner J, Bornfeldt KE, Fisher EA, Dixit VD, et al. Adipose tissue macrophages promote myelopoiesis and monocytosis in obesity. Cell Metabolism. 19: 821-35. PMID 24807222 DOI: 10.1016/j.cmet.2014.03.029  0.32
2014 Panchatcharam M, Salous AK, Brandon J, Miriyala S, Wheeler J, Patil P, Sunkara M, Morris AJ, Escalante-Alcalde D, Smyth SS. Mice with targeted inactivation of ppap2b in endothelial and hematopoietic cells display enhanced vascular inflammation and permeability. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 837-45. PMID 24504738 DOI: 10.1161/ATVBAHA.113.302335  0.32
2014 Smyth SS, Mueller P, Yang F, Brandon JA, Morris AJ. Arguing the case for the autotaxin-lysophosphatidic acid-lipid phosphate phosphatase 3-signaling nexus in the development and complications of atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 479-86. PMID 24482375 DOI: 10.1161/ATVBAHA.113.302737  0.32
2014 Storey RF, Kotha J, Smyth SS, Moliterno DJ, Rorick TL, Moccetti T, Valgimigli M, Dery JP, Cornel JH, Thomas GS, Huber K, Harrington RA, Hord E, Judge HM, Chen E, et al. Effects of vorapaxar on platelet reactivity and biomarker expression in non-ST-elevation acute coronary syndromes. The TRACER Pharmacodynamic Substudy. Thrombosis and Haemostasis. 111: 883-91. PMID 24402559 DOI: 10.1160/TH13-07-0624  0.32
2014 Wu T, Kooi CV, Shah P, Charnigo R, Huang C, Smyth SS, Morris AJ. Integrin-mediated cell surface recruitment of autotaxin promotes persistent directional cell migration. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 861-70. PMID 24277575 DOI: 10.1096/fj.13-232868  0.32
2013 Xiang B, Zhang G, Guo L, Li XA, Morris AJ, Daugherty A, Whiteheart SW, Smyth SS, Li Z. Platelets protect from septic shock by inhibiting macrophage-dependent inflammation via the cyclooxygenase 1 signalling pathway. Nature Communications. 4: 2657. PMID 24150174 DOI: 10.1038/ncomms3657  0.56
2013 Park GY, Lee YG, Berdyshev E, Nyenhuis S, Du J, Fu P, Gorshkova IA, Li Y, Chung S, Karpurapu M, Deng J, Ranjan R, Xiao L, Jaffe HA, Corbridge SJ, ... ... Smyth SS, et al. Autotaxin production of lysophosphatidic acid mediates allergic asthmatic inflammation. American Journal of Respiratory and Critical Care Medicine. 188: 928-40. PMID 24050723 DOI: 10.1164/rccm.201306-1014OC  0.32
2013 Salous AK, Panchatcharam M, Sunkara M, Mueller P, Dong A, Wang Y, Graf GA, Smyth SS, Morris AJ. Mechanism of rapid elimination of lysophosphatidic acid and related lipids from the circulation of mice. Journal of Lipid Research. 54: 2775-84. PMID 23948545 DOI: 10.1194/jlr.M039685  0.32
2013 Wallace EL, Kotter JR, Charnigo R, Kuvlieva LB, Smyth SS, Ziada KM, Campbell CL. Fibrinolytic therapy versus primary percutaneous coronary interventions for ST-segment elevation myocardial infarction in Kentucky: time to establish systems of care? Southern Medical Journal. 106: 391-8. PMID 23820318 DOI: 10.1097/SMJ.0b013e31829ba880  0.32
2013 Rodés-Cabau J, Dauerman HL, Cohen MG, Mehran R, Small EM, Smyth SS, Costa MA, Mega JL, O'Donoghue ML, Ohman EM, Becker RC. Antithrombotic treatment in transcatheter aortic valve implantation: insights for cerebrovascular and bleeding events. Journal of the American College of Cardiology. 62: 2349-59. PMID 23583252 DOI: 10.1016/j.jacc.2013.03.029  0.32
2013 Morris AJ, Smyth SS. Lysophosphatidic acid and cardiovascular disease: seeing is believing. Journal of Lipid Research. 54: 1153-5. PMID 23509404 DOI: 10.1194/jlr.E037887  0.32
2013 Karapetyan AV, Klyachkin YM, Selim S, Sunkara M, Ziada KM, Cohen DA, Zuba-Surma EK, Ratajczak J, Smyth SS, Ratajczak MZ, Morris AJ, Abdel-Latif A. Bioactive lipids and cationic antimicrobial peptides as new potential regulators for trafficking of bone marrow-derived stem cells in patients with acute myocardial infarction. Stem Cells and Development. 22: 1645-56. PMID 23282236 DOI: 10.1089/scd.2012.0488  0.32
2013 Gross AK, Dunn SP, Feola DJ, Martin CA, Charnigo R, Li Z, Abdel-Latif A, Smyth SS. Clopidogrel treatment and the incidence and severity of community acquired pneumonia in a cohort study and meta-analysis of antiplatelet therapy in pneumonia and critical illness. Journal of Thrombosis and Thrombolysis. 35: 147-54. PMID 23124575 DOI: 10.1007/s11239-012-0833-4  0.32
2013 Panchatcharam M, Miriyala S, Salous A, Wheeler J, Dong A, Mueller P, Sunkara M, Escalante-Alcalde D, Morris AJ, Smyth SS. Lipid phosphate phosphatase 3 negatively regulates smooth muscle cell phenotypic modulation to limit intimal hyperplasia. Arteriosclerosis, Thrombosis, and Vascular Biology. 33: 52-9. PMID 23104851 DOI: 10.1161/ATVBAHA.112.300527  0.32
2012 Xiang B, Zhang G, Ren H, Sunkara M, Morris AJ, Gartner TK, Smyth SS, Li Z. The P2Y(12) antagonists, 2MeSAMP and cangrelor, inhibit platelet activation through P2Y(12)/G(i)-dependent mechanism. Plos One. 7: e51037. PMID 23236426 DOI: 10.1371/journal.pone.0051037  0.32
2012 Dong A, Sunkara M, Panchatcharam M, Salous A, Selim S, Morris AJ, Smyth SS. Synergistic effect of anemia and red blood cells transfusion on inflammation and lung injury. Advances in Hematology. 2012: 924042. PMID 22919395 DOI: 10.1155/2012/924042  0.32
2012 Yang F, Dong A, Mueller P, Caicedo J, Sutton AM, Odetunde J, Barrick CJ, Klyachkin YM, Abdel-Latif A, Smyth SS. Coronary artery remodeling in a model of left ventricular pressure overload is influenced by platelets and inflammatory cells. Plos One. 7: e40196. PMID 22916095 DOI: 10.1371/journal.pone.0040196  0.32
2012 Rowley JW, Finn AV, French PA, Jennings LK, Bluestein D, Gross PL, Freedman JE, Steinhubl SR, Zimmerman GA, Becker RC, Dauerman HL, Smyth SS. Cardiovascular devices and platelet interactions: understanding the role of injury, flow, and cellular responses. Circulation. Cardiovascular Interventions. 5: 296-304. PMID 22511738 DOI: 10.1161/CIRCINTERVENTIONS.111.965426  0.32
2012 Federico L, Ren H, Mueller PA, Wu T, Liu S, Popovic J, Blalock EM, Sunkara M, Ovaa H, Albers HM, Mills GB, Morris AJ, Smyth SS. Autotaxin and its product lysophosphatidic acid suppress brown adipose differentiation and promote diet-induced obesity in mice. Molecular Endocrinology (Baltimore, Md.). 26: 786-97. PMID 22474126 DOI: 10.1210/me.2011-1229  0.32
2012 Cheng HY, Dong A, Panchatcharam M, Mueller P, Yang F, Li Z, Mills G, Chun J, Morris AJ, Smyth SS. Lysophosphatidic acid signaling protects pulmonary vasculature from hypoxia-induced remodeling. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 24-32. PMID 22015657 DOI: 10.1161/ATVBAHA.111.234708  0.32
2011 Zhang G, Xiang B, Ye S, Chrzanowska-Wodnicka M, Morris AJ, Gartner TK, Whiteheart SW, White GC, Smyth SS, Li Z. Distinct roles for Rap1b protein in platelet secretion and integrin αIIbβ3 outside-in signaling. The Journal of Biological Chemistry. 286: 39466-77. PMID 21940635 DOI: 10.1074/jbc.M111.239608  0.56
2011 Li Z, Smyth SS. Connexin 37 counteracts clotting. Circulation. 124: 873-5. PMID 21859981 DOI: 10.1161/CIRCULATIONAHA.111.045104  0.32
2011 Fulkerson Z, Wu T, Sunkara M, Kooi CV, Morris AJ, Smyth SS. Binding of autotaxin to integrins localizes lysophosphatidic acid production to platelets and mammalian cells. The Journal of Biological Chemistry. 286: 34654-63. PMID 21832043 DOI: 10.1074/jbc.M111.276725  0.56
2011 Zhang G, Xiang B, Dong A, Skoda RC, Daugherty A, Smyth SS, Du X, Li Z. Biphasic roles for soluble guanylyl cyclase (sGC) in platelet activation. Blood. 118: 3670-9. PMID 21803853 DOI: 10.1182/blood-2011-03-341107  0.32
2011 Selim S, Sunkara M, Salous AK, Leung SW, Berdyshev EV, Bailey A, Campbell CL, Charnigo R, Morris AJ, Smyth SS. Plasma levels of sphingosine 1-phosphate are strongly correlated with haematocrit, but variably restored by red blood cell transfusions. Clinical Science (London, England : 1979). 121: 565-72. PMID 21749329 DOI: 10.1042/CS20110236  0.32
2011 Zhao J, He D, Berdyshev E, Zhong M, Salgia R, Morris AJ, Smyth SS, Natarajan V, Zhao Y. Autotaxin induces lung epithelial cell migration through lysoPLD activity-dependent and -independent pathways. The Biochemical Journal. 439: 45-55. PMID 21696367 DOI: 10.1042/BJ20110274  0.56
2011 Bailey AL, Smyth SS, Campbell CL. The case against routine aspirin use for primary prevention in low-risk adults. American Family Physician. 83: 1387-90. PMID 21671539  0.32
2011 Hausmann J, Kamtekar S, Christodoulou E, Day JE, Wu T, Fulkerson Z, Albers HM, van Meeteren LA, Houben AJ, van Zeijl L, Jansen S, Andries M, Hall T, Pegg LE, Benson TE, ... ... Smyth SS, et al. Structural basis of substrate discrimination and integrin binding by autotaxin. Nature Structural & Molecular Biology. 18: 198-204. PMID 21240271 DOI: 10.1038/nsmb.1980  0.32
2011 Li Z, Yang F, Dunn S, Gross AK, Smyth SS. Platelets as immune mediators: their role in host defense responses and sepsis. Thrombosis Research. 127: 184-8. PMID 21075430 DOI: 10.1016/j.thromres.2010.10.010  0.32
2011 Campbell CL, Steinhubl SR, Hooper WC, Jozic J, Smyth SS, Bernstein D, De Staercke C, Syros G, Negus BH, Stuckey T, Stone GW, Mehran R, Dangas G. Bleeding events are associated with an increase in markers of inflammation in acute coronary syndromes: an ACUITY trial substudy. Journal of Thrombosis and Thrombolysis. 31: 139-45. PMID 20872045 DOI: 10.1007/s11239-010-0513-1  0.32
2010 Williams MS, Weiss EJ, Sabatine MS, Simon DI, Bahou WF, Becker LC, Parise LV, Dauerman HL, French PA, Smyth SS, Becker RC. Genetic regulation of platelet receptor expression and function: application in clinical practice and drug development. Arteriosclerosis, Thrombosis, and Vascular Biology. 30: 2372-84. PMID 21084706 DOI: 10.1161/ATVBAHA.110.218131  0.32
2010 Abdel-Latif A, Zuba-Surma EK, Ziada KM, Kucia M, Cohen DA, Kaplan AM, Van Zant G, Selim S, Smyth SS, Ratajczak MZ. Evidence of mobilization of pluripotent stem cells into peripheral blood of patients with myocardial ischemia. Experimental Hematology. 38: 1131-1142.e1. PMID 20800644 DOI: 10.1016/j.exphem.2010.08.003  0.32
2010 Ren H, Federico L, Huang H, Sunkara M, Drennan T, Frohman MA, Smyth SS, Morris AJ. A phosphatidic acid binding/nuclear localization motif determines lipin1 function in lipid metabolism and adipogenesis. Molecular Biology of the Cell. 21: 3171-81. PMID 20660155 DOI: 10.1091/mbc.E10-01-0073  0.32
2010 Albers HM, Dong A, van Meeteren LA, Egan DA, Sunkara M, van Tilburg EW, Schuurman K, van Tellingen O, Morris AJ, Smyth SS, Moolenaar WH, Ovaa H. Boronic acid-based inhibitor of autotaxin reveals rapid turnover of LPA in the circulation. Proceedings of the National Academy of Sciences of the United States of America. 107: 7257-62. PMID 20360563 DOI: 10.1073/pnas.1001529107  0.32
2010 Panchatcharam M, Miriyala S, Yang F, Leitges M, Chrzanowska-Wodnicka M, Quilliam LA, Anaya P, Morris AJ, Smyth SS. Enhanced proliferation and migration of vascular smooth muscle cells in response to vascular injury under hyperglycemic conditions is controlled by beta3 integrin signaling. The International Journal of Biochemistry & Cell Biology. 42: 965-74. PMID 20184965 DOI: 10.1016/j.biocel.2010.02.009  0.32
2010 Miriyala S, Subramanian T, Panchatcharam M, Ren H, McDermott MI, Sunkara M, Drennan T, Smyth SS, Spielmann HP, Morris AJ. Functional characterization of the atypical integral membrane lipid phosphatase PDP1/PPAPDC2 identifies a pathway for interconversion of isoprenols and isoprenoid phosphates in mammalian cells. The Journal of Biological Chemistry. 285: 13918-29. PMID 20110354 DOI: 10.1074/jbc.M109.083931  0.32
2010 Li G, Jin R, Norris RA, Zhang L, Yu S, Wu F, Markwald RR, Nanda A, Conway SJ, Smyth SS, Granger DN. Periostin mediates vascular smooth muscle cell migration through the integrins alphavbeta3 and alphavbeta5 and focal adhesion kinase (FAK) pathway. Atherosclerosis. 208: 358-65. PMID 19695571 DOI: 10.1016/j.atherosclerosis.2009.07.046  0.32
2009 Morris AJ, Selim S, Salous A, Smyth SS. Blood relatives: dynamic regulation of bioactive lysophosphatidic acid and sphingosine-1-phosphate metabolism in the circulation. Trends in Cardiovascular Medicine. 19: 135-40. PMID 19818950 DOI: 10.1016/j.tcm.2009.07.005  0.56
2009 Morris AJ, Panchatcharam M, Cheng HY, Federico L, Fulkerson Z, Selim S, Miriyala S, Escalante-Alcalde D, Smyth SS. Regulation of blood and vascular cell function by bioactive lysophospholipids. Journal of Thrombosis and Haemostasis : Jth. 7: 38-43. PMID 19630765 DOI: 10.1111/j.1538-7836.2009.03405.x  0.56
2009 Barrick CJ, Dong A, Waikel R, Corn D, Yang F, Threadgill DW, Smyth SS. Parent-of-origin effects on cardiac response to pressure overload in mice. American Journal of Physiology. Heart and Circulatory Physiology. 297: H1003-9. PMID 19561308 DOI: 10.1152/ajpheart.00896.2008  0.32
2009 Barrick CJ, Roberts RB, Rojas M, Rajamannan NM, Suitt CB, O'Brien KD, Smyth SS, Threadgill DW. Reduced EGFR causes abnormal valvular differentiation leading to calcific aortic stenosis and left ventricular hypertrophy in C57BL/6J but not 129S1/SvImJ mice. American Journal of Physiology. Heart and Circulatory Physiology. 297: H65-75. PMID 19448146 DOI: 10.1152/ajpheart.00866.2008  0.32
2009 Oestreich JH, Holt J, Dunn SP, Smyth SS, Campbell CL, Charnigo R, Akers WS, Steinhubl SR. Considerable variability in platelet activity among patients with coronary artery disease in response to an increased maintenance dose of clopidogrel. Coronary Artery Disease. 20: 207-13. PMID 19318928 DOI: 10.1097/MCA.0b013e328329924b  0.32
2009 Oestreich JH, Smyth SS, Campbell CL. Platelet function analysis: at the edge of meaning. Thrombosis and Haemostasis. 101: 217-9. PMID 19190799 DOI: 10.1160/TH08-12-0782  0.32
2009 Meredith D, Panchatcharam M, Miriyala S, Tsai YS, Morris AJ, Maeda N, Stouffer GA, Smyth SS. Dominant-negative loss of PPARgamma function enhances smooth muscle cell proliferation, migration, and vascular remodeling. Arteriosclerosis, Thrombosis, and Vascular Biology. 29: 465-71. PMID 19179641 DOI: 10.1161/ATVBAHA.109.184234  0.56
2009 Pamuklar Z, Federico L, Liu S, Umezu-Goto M, Dong A, Panchatcharam M, Fulkerson Z, Fulerson Z, Berdyshev E, Natarajan V, Fang X, van Meeteren LA, Moolenaar WH, Mills GB, Morris AJ, ... Smyth SS, et al. Autotaxin/lysopholipase D and lysophosphatidic acid regulate murine hemostasis and thrombosis. The Journal of Biological Chemistry. 284: 7385-94. PMID 19139100 DOI: 10.1074/jbc.M807820200  0.56
2009 Smyth SS, Woulfe DS, Weitz JI, Gachet C, Conley PB, Goodman SG, Roe MT, Kuliopulos A, Moliterno DJ, French PA, Steinhubl SR, Becker RC. G-protein-coupled receptors as signaling targets for antiplatelet therapy. Arteriosclerosis, Thrombosis, and Vascular Biology. 29: 449-57. PMID 19023091 DOI: 10.1161/ATVBAHA.108.176388  0.32
2008 Panchatcharam M, Miriyala S, Yang F, Rojas M, End C, Vallant C, Dong A, Lynch K, Chun J, Morris AJ, Smyth SS. Lysophosphatidic acid receptors 1 and 2 play roles in regulation of vascular injury responses but not blood pressure. Circulation Research. 103: 662-70. PMID 18703779 DOI: 10.1161/CIRCRESAHA.108.180778  0.32
2008 Federico L, Pamuklar Z, Smyth SS, Morris AJ. Therapeutic potential of autotaxin/lysophospholipase d inhibitors. Current Drug Targets. 9: 698-708. PMID 18691016  0.56
2008 Smyth SS, Cheng HY, Miriyala S, Panchatcharam M, Morris AJ. Roles of lysophosphatidic acid in cardiovascular physiology and disease. Biochimica Et Biophysica Acta. 1781: 563-70. PMID 18586114 DOI: 10.1016/j.bbalip.2008.05.008  0.56
2008 Pamuklar Z, Lee JS, Cheng HY, Panchatcharam M, Steinhubl S, Morris AJ, Charnigo R, Smyth SS. Individual heterogeneity in platelet response to lysophosphatidic acid: evidence for a novel inhibitory pathway. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 555-61. PMID 18202325 DOI: 10.1161/ATVBAHA.107.151837  0.56
2007 Morris AJ, Smyth SS. Measurement of autotaxin/lysophospholipase D activity. Methods in Enzymology. 434: 89-104. PMID 17954243 DOI: 10.1016/S0076-6879(07)34005-6  0.32
2007 Li G, Keenan AC, Young JC, Hall MJ, Pamuklar Z, Ohman EM, Steinhubl SR, Smyth SS. Effects of unfractionated heparin and glycoprotein IIb/IIIa antagonists versus bivalirdin on myeloperoxidase release from neutrophils. Arteriosclerosis, Thrombosis, and Vascular Biology. 27: 1850-6. PMID 17525363 DOI: 10.1161/ATVBAHA.107.144576  0.56
2007 Dorsch MP, Lee JS, Lynch DR, Dunn SP, Rodgers JE, Schwartz T, Colby E, Montague D, Smyth SS. Aspirin resistance in patients with stable coronary artery disease with and without a history of myocardial infarction. The Annals of Pharmacotherapy. 41: 737-41. PMID 17456544 DOI: 10.1345/aph.1H621  0.32
2007 Lee JS, Dunn SP, Marshall HM, Cohen MG, Smyth SS. A case report of simultaneous thrombosis of two coronary artery stents in association with clopidogrel resistance. Clinical Cardiology. 30: 200-3. PMID 17443655 DOI: 10.1002/clc.9  0.32
2007 Barrick CJ, Rojas M, Schoonhoven R, Smyth SS, Threadgill DW. Cardiac response to pressure overload in 129S1/SvImJ and C57BL/6J mice: temporal- and background-dependent development of concentric left ventricular hypertrophy. American Journal of Physiology. Heart and Circulatory Physiology. 292: H2119-30. PMID 17172276 DOI: 10.1152/ajpheart.00816.2006  0.32
2007 Evangelista V, Pamuklar Z, Piccoli A, Manarini S, Dell'elba G, Pecce R, Martelli N, Federico L, Rojas M, Berton G, Lowell CA, Totani L, Smyth SS. Src family kinases mediate neutrophil adhesion to adherent platelets. Blood. 109: 2461-9. PMID 17095622 DOI: 10.1182/blood-2006-06-029082  0.56
2006 Totani L, Piccoli A, Manarini S, Federico L, Pecce R, Martelli N, Cerletti C, Piccardoni P, Lowell CA, Smyth SS, Berton G, Evangelista V. Src-family kinases mediate an outside-in signal necessary for beta2 integrins to achieve full activation and sustain firm adhesion of polymorphonuclear leucocytes tethered on E-selectin. The Biochemical Journal. 396: 89-98. PMID 16433632 DOI: 10.1042/BJ20051924  0.56
2005 Chrzanowska-Wodnicka M, Smyth SS, Schoenwaelder SM, Fischer TH, White GC. Rap1b is required for normal platelet function and hemostasis in mice. The Journal of Clinical Investigation. 115: 680-7. PMID 15696195 DOI: 10.1172/JCI22973  0.32
2003 Smyth SS, Sciorra VA, Sigal YJ, Pamuklar Z, Wang Z, Xu Y, Prestwich GD, Morris AJ. Lipid phosphate phosphatases regulate lysophosphatidic acid production and signaling in platelets: studies using chemical inhibitors of lipid phosphate phosphatase activity. The Journal of Biological Chemistry. 278: 43214-23. PMID 12909631 DOI: 10.1074/jbc.M306709200  0.32
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