Mariana Nikolova-Karakashian - Publications

Physiology University of Kentucky, Lexington, KY 
Biochemistry, Physiology Biology

36 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Deevska GM, Nikolova-Karakashian MN. The expanding role of sphingolipids in lipid droplet biogenesis. Biochimica Et Biophysica Acta. PMID 28743537 DOI: 10.1016/j.bbalip.2017.07.008  0.32
2017 Nolan MW, Gieger TL, Karakashian AA, Nikolova-Karakashian MN, Posner LP, Roback DM, Rivera JN, Chang S. Outcomes of Spatially Fractionated Radiotherapy (GRID) for Bulky Soft Tissue Sarcomas in a Large Animal Model. Technology in Cancer Research & Treatment. 1533034617690980. PMID 28168937 DOI: 10.1177/1533034617690980  0.48
2017 Deevska GM, Dotson PP, Karakashian AA, Isaac G, Wrona M, Kelly SB, Merrill AH, Nikolova-Karakashian MN. Novel interconnections in lipid metabolism revealed by overexpression of sphingomyelin synthase-1. The Journal of Biological Chemistry. PMID 28087695 DOI: 10.1074/jbc.M116.751602  0.48
2016 Shi L, Banerjee D, Dobierzewska A, Sabapathi S, Karakashian A, Giltiay N, Nikolova-Karakashian MN. Direct regulation of IGF Binding Protein 1 (IGFBP1) Promoter by Interleukin 1β via insulin- and FoxO-1 independent mechanism. American Journal of Physiology. Endocrinology and Metabolism. ajpendo.00289.2015. PMID 26884383 DOI: 10.1152/ajpendo.00289.2015  1
2015 Dotson PP, Karakashian AA, Nikolova-Karakashian MN. Neutral sphingomyelinase-2 is a redox sensitive enzyme: role of catalytic cysteine residues in regulation of enzymatic activity through changes in oligomeric state. The Biochemical Journal. 465: 371-82. PMID 25287744 DOI: 10.1042/BJ20140665  0.48
2014 Moylan JS, Smith JD, Wolf Horrell EM, McLean JB, Deevska GM, Bonnell MR, Nikolova-Karakashian MN, Reid MB. Neutral sphingomyelinase-3 mediates TNF-stimulated oxidant activity in skeletal muscle. Redox Biology. 2: 910-20. PMID 25180167 DOI: 10.1016/j.redox.2014.07.006  1
2014 Deevska G, Sunkara M, Karakashian C, Peppers B, Morris AJ, Nikolova-Karakashian MN. Effect of procysteine on aging-associated changes in hepatic GSH and SMase: evidence for transcriptional regulation of smpd3. Journal of Lipid Research. 55: 2041-52. PMID 25047167 DOI: 10.1194/jlr.M048223  1
2014 Empinado HM, Deevska GM, Nikolova-Karakashian M, Yoo JK, Christou DD, Ferreira LF. Diaphragm dysfunction in heart failure is accompanied by increases in neutral sphingomyelinase activity and ceramide content. European Journal of Heart Failure. 16: 519-25. PMID 24596158 DOI: 10.1002/ejhf.73  0.32
2012 Dobierzewska A, Shi L, Karakashian AA, Nikolova-Karakashian MN. Interleukin 1β regulation of FoxO1 protein content and localization: evidence for a novel ceramide-dependent mechanism. The Journal of Biological Chemistry. 287: 44749-60. PMID 23105097 DOI: 10.1074/jbc.M112.378836  0.48
2012 Deevska GM, Sunkara M, Morris AJ, Nikolova-Karakashian MN. Characterization of secretory sphingomyelinase activity, lipoprotein sphingolipid content and LDL aggregation in ldlr-/- mice fed on a high-fat diet. Bioscience Reports. 32: 479-90. PMID 22712892 DOI: 10.1042/BSR20120036  1
2011 Dobierzewska A, Giltiay NV, Sabapathi S, Karakashian AA, Nikolova-Karakashian MN. Protein phosphatase 2A and neutral sphingomyelinase 2 regulate IRAK-1 protein ubiquitination and degradation in response to interleukin-1beta. The Journal of Biological Chemistry. 286: 32064-73. PMID 21708940 DOI: 10.1074/jbc.M111.238030  0.48
2011 Nikolova-Karakashian MN, Reid MB. Sphingolipid metabolism, oxidant signaling, and contractile function of skeletal muscle. Antioxidants & Redox Signaling. 15: 2501-17. PMID 21453197 DOI: 10.1089/ars.2011.3940  1
2011 Deevska GM, Nikolova-Karakashian MN. The twists and turns of sphingolipid pathway in glucose regulation. Biochimie. 93: 32-8. PMID 20561942 DOI: 10.1016/j.biochi.2010.05.016  0.32
2010 Nikolova-Karakashian MN, Rozenova KA. Ceramide in stress response. Advances in Experimental Medicine and Biology. 688: 86-108. PMID 20919648  0.76
2010 Ferreira LF, Moylan JS, Gilliam LA, Smith JD, Nikolova-Karakashian M, Reid MB. Sphingomyelinase stimulates oxidant signaling to weaken skeletal muscle and promote fatigue. American Journal of Physiology. Cell Physiology. 299: C552-60. PMID 20519448 DOI: 10.1152/ajpcell.00065.2010  1
2010 Rozenova KA, Deevska GM, Karakashian AA, Nikolova-Karakashian MN. Studies on the role of acid sphingomyelinase and ceramide in the regulation of tumor necrosis factor alpha (TNFalpha)-converting enzyme activity and TNFalpha secretion in macrophages. The Journal of Biological Chemistry. 285: 21103-13. PMID 20236926 DOI: 10.1074/jbc.M109.080671  0.76
2009 Deevska GM, Rozenova KA, Giltiay NV, Chambers MA, White J, Boyanovsky BB, Wei J, Daugherty A, Smart EJ, Reid MB, Merrill AH, Nikolova-Karakashian M. Acid Sphingomyelinase Deficiency Prevents Diet-induced Hepatic Triacylglycerol Accumulation and Hyperglycemia in Mice. The Journal of Biological Chemistry. 284: 8359-68. PMID 19074137 DOI: 10.1074/jbc.M807800200  1
2008 Nikolova-Karakashian M, Karakashian A, Rutkute K. Role of neutral sphingomyelinases in aging and inflammation. Sub-Cellular Biochemistry. 49: 469-86. PMID 18751923 DOI: 10.1007/978-1-4020-8831-5_18  1
2007 Rutkute K, Asmis RH, Nikolova-Karakashian MN. Regulation of neutral sphingomyelinase-2 by GSH: a new insight to the role of oxidative stress in aging-associated inflammation. Journal of Lipid Research. 48: 2443-52. PMID 17693623 DOI: 10.1194/jlr.M700227-JLR200  1
2007 Rutkute K, Karakashian AA, Giltiay NV, Dobierzewska A, Nikolova-Karakashian MN. Aging in rat causes hepatic hyperresposiveness to interleukin-1beta which is mediated by neutral sphingomyelinase-2. Hepatology (Baltimore, Md.). 46: 1166-76. PMID 17668873 DOI: 10.1002/hep.21777  1
2007 Rutkute K, Nikolova-Karakashian MN. Regulation of insulin-like growth factor binding protein-1 expression during aging. Biochemical and Biophysical Research Communications. 361: 263-9. PMID 17645865 DOI: 10.1016/j.bbrc.2007.06.079  1
2006 Li XA, Guo L, Asmis R, Nikolova-Karakashian M, Smart EJ. Scavenger receptor BI prevents nitric oxide-induced cytotoxicity and endotoxin-induced death. Circulation Research. 98: e60-5. PMID 16574909 DOI: 10.1161/01.RES.0000219310.00308.10  1
2005 Giltiay NV, Karakashian AA, Alimov AP, Ligthle S, Nikolova-Karakashian MN. Ceramide- and ERK-dependent pathway for the activation of CCAAT/enhancer binding protein by interleukin-1beta in hepatocytes. Journal of Lipid Research. 46: 2497-505. PMID 16106045 DOI: 10.1194/jlr.M500337-JLR200  0.48
2005 Sathishkumar S, Boyanovsky B, Karakashian AA, Rozenova K, Giltiay NV, Kudrimoti M, Mohiuddin M, Ahmed MM, Nikolova-Karakashian M. Elevated sphingomyelinase activity and ceramide concentration in serum of patients undergoing high dose spatially fractionated radiation treatment: implications for endothelial apoptosis. Cancer Biology & Therapy. 4: 979-86. PMID 16096366  0.48
2004 Karakashian AA, Giltiay NV, Smith GM, Nikolova-Karakashian MN. Expression of neutral sphingomyelinase-2 (NSMase-2) in primary rat hepatocytes modulates IL-β-induced JNK activation Faseb Journal. 18: 968-970. PMID 15059969 DOI: 10.1096/fj.03-0875fje  1
2003 Boyanovsky B, Karakashian A, King K, Giltiay N, Nikolova-Karakashian M. Uptake and metabolism of low density lipoproteins with elevated ceramide content by human microvascular endothelial cells: implications for the regulation of apoptosis. The Journal of Biological Chemistry. 278: 26992-9. PMID 12721293 DOI: 10.1074/jbc.M301536200  0.76
2002 Claycombe KJ, Wu D, Nikolova-Karakashian M, Palmer H, Beharka A, Paulson KE, Meydani SN. Ceramide mediates age-associated increase in macrophage cyclooxygenase-2 expression. The Journal of Biological Chemistry. 277: 30784-91. PMID 12072440 DOI: 10.1074/jbc.M204463200  1
2002 Li XA, Titlow WB, Jackson BA, Giltiay N, Nikolova-Karakashian M, Uittenbogaard A, Smart EJ. High density lipoprotein binding to scavenger receptor, Class B, type I activates endothelial nitric-oxide synthase in a ceramide-dependent manner. The Journal of Biological Chemistry. 277: 11058-63. PMID 11792700 DOI: 10.1074/jbc.M110985200  1
2002 Deaciuc IV, D'Souza NB, Nikolova-Karakashian M, De Villiers WJS, Sarphie TG, Hill DB, McClain CJ. The regulation of Fas (CD95/Apo-1)-mediated liver apoptosis in Kupffer cell-depleted mice Hepatology Research. 24: 192-204. DOI: 10.1016/S1386-6346(02)00021-9  1
2000 Yu ZF, Nikolova-Karakashian M, Zhou D, Cheng G, Schuchman EH, Mattson MP. Pivotal role for acidic sphingomyelinase in cerebral ischemia-induced ceramide and cytokine production, and neuronal apoptosis Journal of Molecular Neuroscience. 15: 85-97. PMID 11220788 DOI: 10.1385/JMN:15:2:85  1
1999 Merrill AH, Nikolova-Karakashian M, Schmelz EM, Morgan ET, Stewart J. Regulation of cytochrome P450 expression by sphingolipids Chemistry and Physics of Lipids. 102: 131-139. PMID 11001567 DOI: 10.1016/S0009-3084(99)00081-X  1
1999 Merrill AH, Morgan ET, Nikolova-Karakashian M, Stewart J. Sphingomyelin hydrolysis and regulation of the expression of the gene for cytochrome P450 Biochemical Society Transactions. 27: 383-387. PMID 10917607  1
1997 Kok JW, Nikolova-Karakashian M, Klappe K, Alexander C, Merrill AH. Dihydroceramide biology. Structure-specific metabolism and intracellular localization Journal of Biological Chemistry. 272: 21128-21136. PMID 9261117 DOI: 10.1074/jbc.272.34.21128  1
1997 Nikolova-Karakashian M, Morgan ET, Alexander C, Liotta DC, Merrill AH. Bimodal regulation of ceramidase by interleukin-1β. Implications for the regulation of cytochrome P450 2C11 (CYP2C11) Journal of Biological Chemistry. 272: 18718-18724. PMID 9228043 DOI: 10.1074/jbc.272.30.18718  1
1996 Morgan ET, Nikolova-Karakashian M, Chen JQ, Merrill AH. Sphingolipid-dependent signaling in regulation of cytochrome P450 expression Methods in Enzymology. 272: 381-388. PMID 8791797  1
1995 Chen J, Nikolova-Karakashian M, Merrill AH, Morgan ET. Regulation of cytochrome P450 2C11 (CYP2C11) gene expression by interleukin-1, sphingomyelin hydrolysis, and ceramides in rat hepatocytes Journal of Biological Chemistry. 270: 25233-25238. PMID 7559661 DOI: 10.1074/jbc.270.42.25233  1
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