| Year |
Citation |
Score |
| 2023 |
Serwetnyk MA, Crowley VM, Brackett CM, Carter TR, Elahi A, Kommalapati VK, Chadli A, Blagg BSJ. Enniatin A Analogues as Novel Hsp90 Inhibitors that Modulate Triple-Negative Breast Cancer. Acs Medicinal Chemistry Letters. 14: 1785-1790. PMID 38116437 DOI: 10.1021/acsmedchemlett.3c00423 |
0.524 |
|
| 2023 |
Eisa NH, Crowley VM, Elahi A, Kommalapati VK, Serwetnyk MA, Llbiyi T, Lu S, Kainth K, Jilani Y, Marasco D, El Andaloussi A, Lee S, Tsai FTF, Rodriguez PC, Munn D, ... ... Chadli A, et al. Enniatin A inhibits the chaperone Hsp90 and unleashes the immune system against triple-negative breast cancer. Iscience. 26: 108308. PMID 38025772 DOI: 10.1016/j.isci.2023.108308 |
0.485 |
|
| 2023 |
Ajith A, Mamouni K, Horuzsko DD, Musa A, Dzutsev AK, Fang JR, Chadli A, Zhu X, Lebedyeva I, Trinchieri G, Horuzsko A. Targeting TREM1 augments antitumor T-cell immunity by inhibiting myeloid-derived suppressor cells and restraining anti-PD-1 resistance. The Journal of Clinical Investigation. PMID 37651197 DOI: 10.1172/JCI167951 |
0.326 |
|
| 2023 |
Patwardhan CA, Kommalapati VK, Llbiyi T, Singh D, Alfa E, Horuzsko A, Korkaya H, Panda S, Reilly CA, Popik V, Chadli A. Capsaicin binds the N-terminus of Hsp90, induces lysosomal degradation of Hsp70, and enhances the anti-tumor effects of 17-AAG (Tanespimycin). Scientific Reports. 13: 13790. PMID 37612326 DOI: 10.1038/s41598-023-40933-9 |
0.756 |
|
| 2019 |
Eisa NH, Jilani Y, Kainth K, Redd P, Lu S, Bougrine O, Abdul Sater H, Patwardhan CA, Shull A, Shi H, Liu K, ElSherbiny NM, Eissa LA, El-Shishtawy MM, Horuzsko A, ... ... Chadli A, et al. The co-chaperone UNC45A is essential for the expression of mitotic kinase NEK7 and tumorigenesis. The Journal of Biological Chemistry. PMID 30737284 DOI: 10.1074/Jbc.Ra118.006597 |
0.724 |
|
| 2018 |
Pinkerton DM, Chow S, Eisa NH, Kainth K, Vanden Berg TJ, Burns JM, Guddat LW, Savage GP, Chadli A, Williams CM. Synthesis of the seco-Limonoid BCD Ring System Identifies a Hsp90 Chaperon Machinery (p23) Inhibitor. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 30570197 DOI: 10.1002/Chem.201805420 |
0.341 |
|
| 2018 |
Poole CJ, Zheng W, Lee H, Young D, Lodh A, Chadli A, van Riggelen J. Targeting the MYC Oncogene in Burkitt Lymphoma through HSP90 Inhibition. Cancers. 10. PMID 30453475 DOI: 10.3390/cancers10110448 |
0.461 |
|
| 2018 |
Lee E, Ouzounova M, Piranlioglu R, Ma MT, Guzel M, Marasco D, Chadli A, Gestwicki JE, Cowell JK, Wicha MS, Hassan KA, Korkaya H. The pleiotropic effects of TNFα in breast cancer subtypes is regulated by TNFAIP3/A20. Oncogene. PMID 30166590 DOI: 10.1038/S41388-018-0472-0 |
0.306 |
|
| 2015 |
Chen F, Haigh S, Yu Y, Benson T, Wang Y, Li X, Dou H, Bagi Z, Verin AD, Stepp DW, Csanyi G, Chadli A, Weintraub NL, Smith SM, Fulton DJ. Nox5 stability and superoxide production Is regulated by C-terminal binding of Hsp90 and CO-chaperones. Free Radical Biology & Medicine. PMID 26456056 DOI: 10.1016/J.Freeradbiomed.2015.09.019 |
0.58 |
|
| 2015 |
Kabbaj FZ, Lu S, Faouzi Mel A, Meddah B, Proksch P, Cherrah Y, Altenbach HJ, Aly AH, Chadli A, Debbab A. Bioactive metabolites from Chaetomium aureum: structure elucidation and inhibition of the Hsp90 machine chaperoning activity. Bioorganic & Medicinal Chemistry. 23: 126-31. PMID 25482429 DOI: 10.1016/J.Bmc.2014.11.021 |
0.446 |
|
| 2015 |
Jilani Y, Lu S, Lei H, Karnitz LM, Chadli A. UNC45A localizes to centrosomes and regulates cancer cell proliferation through ChK1 activation. Cancer Letters. 357: 114-20. PMID 25444911 DOI: 10.1016/J.Canlet.2014.11.009 |
0.507 |
|
| 2015 |
Patwardhan CA, Alfa E, Lu S, Chadli A. Progesterone receptor chaperone complex-based high-throughput screening assay: identification of capsaicin as an inhibitor of the Hsp90 machine. Journal of Biomolecular Screening. 20: 223-9. PMID 25184514 DOI: 10.1177/1087057114549147 |
0.728 |
|
| 2015 |
Kabbaj FZ, Lu S, Faouzi MEA, Meddah B, Proksch P, Cherrah Y, Altenbach HJ, Aly AH, Chadli A, Debbab A. Bioactive metabolites from Chaetomium aureum: Structure elucidation and inhibition of the Hsp90 machine chaperoning activity Bioorganic and Medicinal Chemistry. 23: 126-131. DOI: 10.1016/j.bmc.2014.11.021 |
0.336 |
|
| 2014 |
Paul A, Garcia YA, Zierer B, Patwardhan C, Gutierrez O, Hildenbrand Z, Harris DC, Balsiger HA, Sivils JC, Johnson JL, Buchner J, Chadli A, Cox MB. The cochaperone SGTA (small glutamine-rich tetratricopeptide repeat-containing protein alpha) demonstrates regulatory specificity for the androgen, glucocorticoid, and progesterone receptors. The Journal of Biological Chemistry. 289: 15297-308. PMID 24753260 DOI: 10.1074/Jbc.M113.535229 |
0.708 |
|
| 2014 |
Patwardhan CA, Peterson LB, Blagg B, Chadli A. Abstract 3197: Gedunin inactivates the co-chaperone p23 causing cancer cell death by apoptosis Cancer Research. 74: 3197-3197. DOI: 10.1158/1538-7445.Am2014-3197 |
0.748 |
|
| 2013 |
Patwardhan CA, Fauq A, Peterson LB, Miller C, Blagg BS, Chadli A. Gedunin inactivates the co-chaperone p23 protein causing cancer cell death by apoptosis. The Journal of Biological Chemistry. 288: 7313-25. PMID 23355466 DOI: 10.1074/Jbc.M112.427328 |
0.75 |
|
| 2013 |
Okoye FBC, Lu S, Nworu CS, Esimone CO, Proksch P, Chadli A, Debbab A. Depsidone and diaryl ether derivatives from the fungus Corynespora cassiicola, an endophyte of Gongronema latifolium Tetrahedron Letters. 54: 4210-4214. DOI: 10.1016/J.Tetlet.2013.05.117 |
0.333 |
|
| 2012 |
Chen F, Yu Y, Qian J, Wang Y, Cheng B, Dimitropoulou C, Patel V, Chadli A, Rudic RD, Stepp DW, Catravas JD, Fulton DJ. Opposing actions of heat shock protein 90 and 70 regulate nicotinamide adenine dinucleotide phosphate oxidase stability and reactive oxygen species production. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 2989-99. PMID 23023377 DOI: 10.1161/Atvbaha.112.300361 |
0.544 |
|
| 2011 |
Chen F, Pandey D, Chadli A, Catravas JD, Chen T, Fulton DJ. Hsp90 regulates NADPH oxidase activity and is necessary for superoxide but not hydrogen peroxide production. Antioxidants & Redox Signaling. 14: 2107-19. PMID 21194376 DOI: 10.1089/Ars.2010.3669 |
0.485 |
|
| 2010 |
Chadli A, Felts SJ, Wang Q, Sullivan WP, Botuyan MV, Fauq A, Ramirez-Alvarado M, Mer G. Celastrol inhibits Hsp90 chaperoning of steroid receptors by inducing fibrillization of the Co-chaperone p23. The Journal of Biological Chemistry. 285: 4224-31. PMID 19996313 DOI: 10.1074/Jbc.M109.081018 |
0.601 |
|
| 2008 |
Chadli A, Felts SJ, Toft DO. GCUNC45 is the first Hsp90 co-chaperone to show alpha/beta isoform specificity. The Journal of Biological Chemistry. 283: 9509-12. PMID 18285346 DOI: 10.1074/jbc.C800017200 |
0.458 |
|
| 2008 |
Chadli A, Bruinsma ES, Stensgard B, Toft D. Analysis of Hsp90 cochaperone interactions reveals a novel mechanism for TPR protein recognition. Biochemistry. 47: 2850-7. PMID 18211007 DOI: 10.1021/bi7023332 |
0.429 |
|
| 2006 |
Chadli A, Graham JD, Abel MG, Jackson TA, Gordon DF, Wood WM, Felts SJ, Horwitz KB, Toft D. GCUNC-45 is a novel regulator for the progesterone receptor/hsp90 chaperoning pathway. Molecular and Cellular Biology. 26: 1722-30. PMID 16478993 DOI: 10.1128/Mcb.26.5.1722-1730.2006 |
0.537 |
|
| 2002 |
Hernández MP, Chadli A, Toft DO. HSP40 binding is the first step in the HSP90 chaperoning pathway for the progesterone receptor. The Journal of Biological Chemistry. 277: 11873-81. PMID 11809754 DOI: 10.1074/jbc.M111445200 |
0.491 |
|
| 2002 |
Bouhouche-Chatelier L, Chadli A, Catelli MG. The N-terminal adenosine triphosphate binding domain of Hsp90 is necessary and sufficient for interaction with estrogen receptor. Cell Stress & Chaperones. 6: 297-305. PMID 11795466 DOI: 10.1379/1466-1268(2001)006<0297:TNTATB>2.0.CO;2 |
0.398 |
|
| 2001 |
Chadli A, Bouhouche I, Sullivan W, Stensgard B, McMahon N, Catelli MG, Toft DO. Dimerization and N-terminal domain proximity underlie the function of the molecular chaperone heat shock protein 90. Proceedings of the National Academy of Sciences of the United States of America. 97: 12524-9. PMID 11050175 DOI: 10.1073/PNAS.220430297 |
0.419 |
|
| 2001 |
Marcu MG, Chadli A, Bouhouche I, Catelli M, Neckers LM. The heat shock protein 90 antagonist novobiocin interacts with a previously unrecognized ATP-binding domain in the carboxyl terminus of the chaperone. The Journal of Biological Chemistry. 275: 37181-6. PMID 10945979 DOI: 10.1074/JBC.M003701200 |
0.49 |
|
| 2000 |
Johnson BD, Chadli A, Felts SJ, Bouhouche I, Catelli MG, Toft DO. Hsp90 chaperone activity requires the full-length protein and interaction among its multiple domains. The Journal of Biological Chemistry. 275: 32499-507. PMID 10913439 DOI: 10.1074/JBC.M005195200 |
0.451 |
|
| 1999 |
Driancourt MA, Guet P, Reynaud K, Chadli A, Catelli MG. Presence of an aromatase inhibitor, possibly heat shock protein 90, in dominant follicles of cattle. Journal of Reproduction and Fertility. 115: 45-58. PMID 10341722 DOI: 10.1530/JRF.0.1150045 |
0.314 |
|
| 1999 |
Kang KI, Meng X, Devin-Leclerc J, Bouhouche I, Chadli A, Cadepond F, Baulieu EE, Catelli MG. The molecular chaperone Hsp90 can negatively regulate the activity of a glucocorticosteroid-dependent promoter. Proceedings of the National Academy of Sciences of the United States of America. 96: 1439-44. PMID 9990042 DOI: 10.1073/PNAS.96.4.1439 |
0.484 |
|
| 1999 |
Chadli A, Ladjimi MM, Baulieu EE, Catelli MG. Heat-induced oligomerization of the molecular chaperone Hsp90. Inhibition by ATP and geldanamycin and activation by transition metal oxyanions. The Journal of Biological Chemistry. 274: 4133-9. PMID 9933607 DOI: 10.1074/JBC.274.7.4133 |
0.415 |
|
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