Willem-Hendrik Gispen, Ph.D. - Publications

Affiliations: 
Medical pharmacology Utrecht University, Utrecht, Netherlands 
Area:
Molecular pharmacology en neuropharmacology
Website:
https://profs.library.uu.nl/index.php/profrec/getprofdata/678/55/133/0

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Year Citation  Score
2008 Van Ree JM, Bohus B, Csontos KM, Gispen WH, Greven HM, Nijkamp FP, Opmeer FA, de Rotte GAA, Van Wimersma Greidanus TB, Witter A, de Wied D. γ -Melanotropin and Brain Function Peptides of the Pars Intermedia. 263-276. DOI: 10.1002/9780470720646.ch15  0.729
2003 Ruitenberg MJ, Plant GW, Hamers FP, Wortel J, Blits B, Dijkhuizen PA, Gispen WH, Boer GJ, Verhaagen J. Ex vivo adenoviral vector-mediated neurotrophin gene transfer to olfactory ensheathing glia: effects on rubrospinal tract regeneration, lesion size, and functional recovery after implantation in the injured rat spinal cord. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 7045-58. PMID 12904465  0.626
2002 De Winter F, Oudega M, Lankhorst AJ, Hamers FP, Blits B, Ruitenberg MJ, Pasterkamp RJ, Gispen WH, Verhaagen J. Injury-induced class 3 semaphorin expression in the rat spinal cord. Experimental Neurology. 175: 61-75. PMID 12009760 DOI: 10.1006/exnr.2002.7884  0.612
2000 Brook GA, Houweling DA, Gieling RG, Hermanns T, Joosten EA, Bär DP, Gispen WH, Schmitt AB, Leprince P, Noth J, Nacimiento W. Attempted endogenous tissue repair following experimental spinal cord injury in the rat: involvement of cell adhesion molecules L1 and NCAM? The European Journal of Neuroscience. 12: 3224-38. PMID 10998106 DOI: 10.1046/J.1460-9568.2000.00228.X  0.734
1999 Holtmaat AJ, Huizinga CT, Margolis FL, Gispen WH, Verhaagen J. Transgenic expression of B-50/GAP-43 in mature olfactory neurons triggers downregulation of native B-50/GAP-43 expression in immature olfactory neurons. Brain Research. Molecular Brain Research. 74: 197-207. PMID 10640691 DOI: 10.1016/S0169-328X(99)00263-6  0.786
1998 Aarts LH, Schotman P, Verhaagen J, Schrama LH, Gispen WH. The role of the neural growth associated protein B-50/GAP-43 in morphogenesis. Advances in Experimental Medicine and Biology. 446: 85-106. PMID 10079839 DOI: 10.1007/978-1-4615-4869-0_6  0.604
1998 Duckers HJ, van Dokkum RP, Verhaagen J, van Luijtelaar EL, Coenen AM, Lopes da Silva FH, Gispen WH. Neurotrophic ACTH4-9 analogue therapy normalizes electroencephalographic alterations in chronic experimental allergic encephalomyelitis. The European Journal of Neuroscience. 10: 3709-20. PMID 9875350 DOI: 10.1046/j.1460-9568.1998.00382.x  0.627
1998 Holtmaat AJ, Oestreicher AB, Gispen WH, Verhaagen J. Manipulation of gene expression in the mammalian nervous system: application in the study of neurite outgrowth and neuroregeneration-related proteins. Brain Research. Brain Research Reviews. 26: 43-71. PMID 9600624 DOI: 10.1016/S0165-0173(97)00044-1  0.776
1997 Oestreicher AB, De Graan PN, Gispen WH, Verhaagen J, Schrama LH. B-50, the growth associated protein-43: modulation of cell morphology and communication in the nervous system. Progress in Neurobiology. 53: 627-86. PMID 9447616 DOI: 10.1016/S0301-0082(97)00043-9  0.633
1997 Buffo A, Holtmaat AJ, Savio T, Verbeek JS, Oberdick J, Oestreicher AB, Gispen WH, Verhaagen J, Rossi F, Strata P. Targeted overexpression of the neurite growth-associated protein B-50/GAP-43 in cerebellar Purkinje cells induces sprouting after axotomy but not axon regeneration into growth-permissive transplants. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 8778-91. PMID 9348347 DOI: 10.1523/Jneurosci.17-22-08778.1997  0.793
1997 Holtmaat AJ, Hermens WT, Sonnemans MA, Giger RJ, Van Leeuwen FW, Kaplitt MG, Oestreicher AB, Gispen WH, Verhaagen J. Adenoviral vector-mediated expression of B-50/GAP-43 induces alterations in the membrane organization of olfactory axon terminals in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 6575-86. PMID 9254670 DOI: 10.1523/Jneurosci.17-17-06575.1997  0.787
1997 Duckers HJ, Muller HJ, Verhaagen J, Nicolay K, Gispen WH. Longitudinal in vivo magnetic resonance imaging studies in experimental allergic encephalomyelitis: effect of a neurotrophic treatment on cortical lesion development. Neuroscience. 77: 1163-73. PMID 9130795 DOI: 10.1016/S0306-4522(96)00514-3  0.604
1996 Duckers HJ, van Dokkum RP, Verhaagen J, Lopes da Silva FH, Gispen WH. Functional and neurophysiological evidence of the efficacy of trophic pharmacotherapy using an adrenocorticotrophic hormone4-9 analog in experimental allergic encephalomyelitis, an animal model of multiple sclerosis. Neuroscience. 71: 507-21. PMID 9053803 DOI: 10.1016/0306-4522(95)00451-3  0.642
1996 Holtmaat AJ, Hermens WT, Oestreicher AB, Gispen WH, Kaplitt MG, Verhaagen J. Efficient adenoviral vector-directed expression of a foreign gene to neurons and sustentacular cells in the mouse olfactory neuroepithelium. Brain Research. Molecular Brain Research. 41: 148-56. PMID 8883946 DOI: 10.1016/0169-328X(96)00085-X  0.769
1996 van Rijzingen IM, Gispen WH, Spruijt BM. The ACTH(4-9) analog ORG 2766 and recovery after brain damage in animal models--a review. Behavioural Brain Research. 74: 1-15. PMID 8851911 DOI: 10.1016/0166-4328(95)00039-9  0.345
1996 Ulenkate HJ, Gispen WH, Jennekens FG. Effects of ciliary neurotrophic factor on retrograde cell reaction after facial nerve crush in young adult rats. Brain Research. 717: 29-37. PMID 8738250 DOI: 10.1016/0006-8993(95)01512-4  0.628
1996 Hamers FP, Plantinga LC, Verhaagen J, Neijt JP, Gispen WH. Upregulation of B50/GAP-43 protein mRNA in rat dorsal root ganglia during cisplatin intoxication. Journal of Neuroscience Research. 44: 142-8. PMID 8723222 DOI: 10.1002/(SICI)1097-4547(19960415)44:2<142::AID-JNR6>3.0.CO;2-D  0.657
1995 Ulenkate HJ, Gispen WH, Jennekens FG. No evidence for enhancement of recovery from a crush lesion of a motor nerve in rats by Org2766. Restorative Neurology and Neuroscience. 9: 85-91. PMID 21551836 DOI: 10.3233/Rnn-1995-9203  0.61
1995 Chepkova AN, French P, De Wied D, Ontskul AH, Ramakers GM, Skrebitski VG, Gispen WH, Urban IJ. Long-lasting enhancement of synaptic excitability of CA1/subiculum neurons of the rat ventral hippocampus by vasopressin and vasopressin(4-8). Brain Research. 701: 255-66. PMID 8925289 DOI: 10.1016/0006-8993(95)01006-7  0.606
1995 Verhaagen J, Hermens WT, Dijkhuizen PA, Holtmaat AJ, Gispen WH. Use of viral vectors to promote neuroregeneration. Clinical Neuroscience (New York, N.Y.). 3: 275-83. PMID 8914794  0.771
1995 Holtmaat AJ, Dijkhuizen PA, Oestreicher AB, Romijn HJ, Van der Lugt NM, Berns A, Margolis FL, Gispen WH, Verhaagen J. Directed expression of the growth-associated protein B-50/GAP-43 to olfactory neurons in transgenic mice results in changes in axon morphology and extraglomerular fiber growth. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 7953-65. PMID 8613733 DOI: 10.1523/Jneurosci.15-12-07953.1995  0.794
1995 Zhang YP, Verhaagen J, Hamers FP, Gispen WH. [Elevated expression of B-50 (GAP-43) -mRNA in a subpopulation of olfactory bulb mitral cells following axotomy]. Sheng Li Xue Bao : [Acta Physiologica Sinica]. 47: 38-44. PMID 7784897  0.647
1995 Plantinga LC, Verhaagen J, Edwards PM, Hali M, Brakkee JH, Gispen WH. Pharmacological evidence for the involvement of endogenous alpha-MSH-like peptides in peripheral nerve regeneration. Peptides. 16: 319-24. PMID 7784262 DOI: 10.1016/0196-9781(94)00179-0  0.653
1995 Hol EM, Gispen WH, Bär PR. ACTH-related peptides: receptors and signal transduction systems involved in their neurotrophic and neuroprotective actions. Peptides. 16: 979-93. PMID 7479345 DOI: 10.1016/0196-9781(95)00017-E  0.683
1995 Nacimiento W, Sappok T, Brook GA, Tóth L, Oestreicher AB, Gispen WH, Noth J, Kreutzberg GW. B-50 (GAP-43) in the rat spinal cord caudal to hemisection: lack of intraspinal sprouting by dorsal root axons. Neuroscience Letters. 194: 13-6. PMID 7478195 DOI: 10.1016/0304-3940(95)11707-4  0.511
1994 Verhaagen J, Hermens WT, Kaplitt MG, Pfaff DW, Gispen WH. B-50/GAP-43 expression via a defective herpes simplex virus vector results in persistent morphological changes in non-neuronal cells. Gene Therapy. 1: S81. PMID 8542427  0.614
1994 Duckers HJ, Verhaagen J, de Bruijn E, Gispen WH. Effective use of a neurotrophic ACTH4-9 analogue in the treatment of a peripheral demyelinating syndrome (experimental allergic neuritis). An intervention study. Brain : a Journal of Neurology. 117: 365-74. PMID 8186962  0.651
1994 Joosten EA, Bär PR, Gispen WH. Corticospinal axons and mechanism of target innervation in rat lumbar spinal cord. Brain Research. Developmental Brain Research. 79: 122-7. PMID 8070056 DOI: 10.1016/0165-3806(94)90055-8  0.312
1994 Plantinga LC, Verhaagen J, Wong SL, Edwards PM, Bär PR, Gispen WH. The neurotrophic peptide Org 2766 does not influence the expression of the immediate early gene c-fos following sciatic nerve crush in the rat. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 12: 117-25. PMID 7942087 DOI: 10.1016/0736-5748(94)90004-3  0.652
1994 Gispen WH, Verhaagen J, Bär D. ACTH/MSH-derived peptides and peripheral nerve plasticity: neuropathies, neuroprotection and repair. Progress in Brain Research. 100: 223-9. PMID 7938523 DOI: 10.1016/S0079-6123(08)60789-X  0.787
1994 Ulenkate HJ, Kaal EC, Gispen WH, Jennekens FG. Ciliary neurotrophic factor improves muscle fibre reinnervation after facial nerve crush in young rats. Acta Neuropathologica. 88: 558-64. PMID 7879603 DOI: 10.1007/Bf00296493  0.553
1994 Hol EM, Verhage M, Gispen WH, Bär PR. The role of calcium and cAMP in the mechanism of action of two melanocortins: alpha MSH and the ACTH4-9 analogue Org 2766. Brain Research. 662: 109-16. PMID 7859062 DOI: 10.1016/0006-8993(94)90802-8  0.669
1994 Verhaagen J, Hermens WT, Oestreicher AB, Gispen WH, Rabkin SD, Pfaff DW, Kaplitt MG. Expression of the growth-associated protein B-50/GAP43 via a defective herpes-simplex virus vector results in profound morphological changes in non-neuronal cells. Brain Research. Molecular Brain Research. 26: 26-36. PMID 7854056 DOI: 10.1016/0169-328X(94)90070-1  0.638
1994 Gerritsen van der Hoop R, Hamers FP, Neijt JP, Veldman H, Gispen WH, Jennekens FG. Protection against cisplatin induced neurotoxicity by ORG 2766: histological and electrophysiological evidence. Journal of the Neurological Sciences. 126: 109-15. PMID 7853014 DOI: 10.1016/0022-510X(94)90259-3  0.579
1994 Hol EM, Mandys V, Sodaar P, Gispen WH, Bär PR. Protection by an ACTH4-9 analogue against the toxic effects of cisplatin and taxol on sensory neurons and glial cells in vitro. Journal of Neuroscience Research. 39: 178-85. PMID 7837287 DOI: 10.1002/jnr.490390208  0.667
1994 Hol EM, Gispen WH, Bär PR. Involvement of calcium and cAMP in the mechanism of action of two melanocortins: alpha MSH and an ACTH-(4-9) analogue. Annals of the New York Academy of Sciences. 739: 324-7. PMID 7832486 DOI: 10.1111/J.1749-6632.1994.Tb19836.X  0.646
1994 Plantinga LC, Schrama LH, Eggen BJ, Gispen WH, Verhaagen J, Lemke G. B-50/GAP-43 mRNA expression in cultured primary Schwann cells is regulated by cyclic AMP. Neuroreport. 5: 2465-8. PMID 7696581 DOI: 10.1097/00001756-199412000-00015  0.639
1994 Duckers H, van Dokkum R, Verhaagen J, Gispen W. A neurotrophic ACTH(4–9) analogue prevents the formation of central demyelinating lesions in CEAE and normalizes central conduction slowing Journal of Neuroimmunology. 54: 164. DOI: 10.1016/0165-5728(94)90333-6  0.599
1993 Ulenkate HJ, Verhaagen J, Plantinga LC, Mercken M, Veldman H, Jennekens FG, Gispen WH, Oestreicher AB. Upregulation of B-50/GAP-43 in Schwann cells at denervated motor endplates and in motoneurons after rat facial nerve crush. Restorative Neurology and Neuroscience. 6: 35-47. PMID 21551729 DOI: 10.3233/Rnn-1993-6104  0.747
1993 Plantinga LC, Verhaagen J, Gispen WH. The expression of B-50/GAP-43 in Schwann cells. Annals of the New York Academy of Sciences. 679: 412-7. PMID 8512206 DOI: 10.1111/j.1749-6632.1993.tb18331.x  0.62
1993 Plantinga LC, Verhaagen J, Edwards PM, Hol EM, Bär PR, Gispen WH. The expression of B-50/GAP-43 in Schwann cells is upregulated in degenerating peripheral nerve stumps following nerve injury. Brain Research. 602: 69-76. PMID 8448659 DOI: 10.1016/0006-8993(93)90243-G  0.782
1993 Nacimiento W, Mautes A, Töpper R, Oestreicher AB, Gispen WH, Nacimiento AC, Noth J, Kreutzberg GW. B-50 (GAP-43) in the spinal cord caudal to hemisection: indication for lack of intraspinal sprouting in dorsal root axons. Journal of Neuroscience Research. 35: 603-17. PMID 8411265 DOI: 10.1002/Jnr.490350604  0.481
1993 Hol EM, Hermens WT, Verhaagen J, Gispen WH, Bär PR. alpha MSH but not Org 2766 induces expression of c-fos in cultured rat spinal cord cells. Neuroreport. 4: 651-4. PMID 8394152  0.765
1993 Hol EM, van Essen EH, Gispen WH, Bär PR. alpha-MSH and ACTH4-9 analogue Org 2766 induce a cAMP increase in cultured rat spinal cord cells. Annals of the New York Academy of Sciences. 680: 533-5. PMID 8390185  0.648
1993 Duckers HJ, Verhaagen J, Gispen WH. A neurotrophic analogue of ACTH4-9 protects against experimental allergic neuritis. Annals of the New York Academy of Sciences. 680: 493-5. PMID 8390175  0.582
1993 Hamers FP, Pette C, Bravenboer B, Vecht CJ, Neijt JP, Gispen WH. Cisplatin-induced neuropathy in mature rats: effects of the melanocortin-derived peptide ORG 2766. Cancer Chemotherapy and Pharmacology. 32: 162-6. PMID 8387400 DOI: 10.1007/Bf00685621  0.394
1993 Bär PR, Renkema GH, Veraart CM, Hol EM, Gispen WH. Nimodipine protects cultured spinal cord neurones from depolarization-induced inhibition of neurite outgrowth. Cell Calcium. 14: 293-9. PMID 8370065 DOI: 10.1016/0143-4160(93)90050-G  0.649
1993 Nacimiento W, Töpper R, Fischer A, Möbius E, Oestreicher AB, Gispen WH, Nacimiento AC, Noth J, Kreutzberg GW. B-50 (GAP-43) in Onuf's nucleus of the adult cat. Brain Research. 613: 80-7. PMID 8348306 DOI: 10.1016/0006-8993(93)90457-X  0.482
1993 Nacimiento W, Töpper R, Fischer A, Oestreicher AB, Nacimiento AC, Gispen WH, Noth J, Kreutzberg GW. Immunocytochemistry of B-50 (GAP-43) in the spinal cord and in dorsal root ganglia of the adult cat. Journal of Neurocytology. 22: 413-24. PMID 8345365 DOI: 10.1007/BF01181562  0.5
1993 Verhaagen J, Zhang Y, Hamers FP, Gispen WH. Elevated expression of B-50 (GAP-43)-mRNA in a subpopulation of olfactory bulb mitral cells following axotomy. Journal of Neuroscience Research. 35: 162-9. PMID 8320748 DOI: 10.1002/jnr.490350206  0.669
1993 Ulenkate HJ, Verhagen MA, Gispen WH, Jennekens FG. The neurotrophic analogue of ACTH(4-9) reduces the perineuronal microglial reaction after rat facial nerve crush. Glia. 9: 219-26. PMID 8294151 DOI: 10.1002/Glia.440090307  0.628
1993 Hesselmans LF, Wieneke GH, Oey PL, Groenhout DM, van der Graaf Y, Gispen WH, Jennekens FG. Evaluation of electrophysiological and clinical tests in an exploratory trial of Org 2766 in motor neuron disease. Neuromuscular Disorders : Nmd. 3: 319-25. PMID 8268729 DOI: 10.1016/0960-8966(93)90025-F  0.491
1993 Florijn WJ, Holtmaat AJ, de Lang H, Spierenburg H, Gispen WH, Versteeg DH. Peptide-induced grooming behavior and caudate nucleus dopamine release. Brain Research. 625: 169-72. PMID 8242396 DOI: 10.1016/0006-8993(93)90151-C  0.732
1993 Duckers HJ, Verhaagen J, Gispen WH. The neurotrophic analogue of ACTH(4-9), Org 2766, protects against experimental allergic neuritis. Brain : a Journal of Neurology. 116: 1059-75. PMID 8221047  0.656
1993 Bär PR, Hol EM, Gispen WH. Trophic effects of melanocortins on neuronal cells in culture. Annals of the New York Academy of Sciences. 692: 284-6. PMID 8215033  0.627
1993 Versteeg DH, Florijn WJ, Holtmaat AJ, Gispen WH, De Wildt DJ. Synchronism of pressor response and grooming behavior in freely moving, conscious rats following intracerebroventricular administration of ACTH/MSH-like peptides. Brain Research. 631: 265-9. PMID 8131054 DOI: 10.1016/0006-8993(93)91544-3  0.738
1993 Hamers FP, Pette C, Neijt JP, Gispen WH. The ACTH-(4-9) analog, ORG 2766, prevents taxol-induced neuropathy in rats. European Journal of Pharmacology. 233: 177-8. PMID 8097161 DOI: 10.1016/0014-2999(93)90367-Q  0.361
1992 Ramakers GJ, Verhaagen J, Oestreicher AB, Margolis FL, van Bergen en Henegouwen PM, Gispen WH. Immunolocalization of B-50 (GAP-43) in the mouse olfactory bulb: predominant presence in preterminal axons. Journal of Neurocytology. 21: 853-69. PMID 1469462 DOI: 10.1007/Bf01191683  0.64
1992 van der Neut R, Hol EM, Gispen WH, Bär PR. Stimulation by melanocortins of neurite outgrowth from spinal and sensory neurons in vitro. Peptides. 13: 1109-15. PMID 1337376 DOI: 10.1016/0196-9781(92)90015-U  0.681
1992 Plantinga LC, Verhaagen J, Edwards PM, Schrama LH, Burbach JP, Gispen WH. Expression of the pro-opiomelanocortin gene in dorsal root ganglia, spinal cord and sciatic nerve after sciatic nerve crush in the rat. Brain Research. Molecular Brain Research. 16: 135-42. PMID 1334192 DOI: 10.1016/0169-328X(92)90203-N  0.659
1992 Gispen WH, Hamers FP, Vecht CJ, Jennekens FG, Neyt JP. ACTH/MSH like peptides in the treatment of cisplatin neuropathy. The Journal of Steroid Biochemistry and Molecular Biology. 43: 179-83. PMID 1326318  0.565
1990 Gispen WH, Boonstra J, De Graan PN, Jennekens FG, Oestreicher AB, Schotman P, Schrama LH, Verhaagen J, Margolis FL. B-50/GAP-43 in neuronal development and repair. Restorative Neurology and Neuroscience. 1: 237-44. PMID 21551562 DOI: 10.3233/Rnn-1990-13410  0.755
1990 van der Hoop RG, Vecht CJ, van der Burg ME, Elderson A, Boogerd W, Heimans JJ, Vries EP, van Houwelingen JC, Jennekens FG, Gispen WH. Prevention of cisplatin neurotoxicity with an ACTH(4-9) analogue in patients with ovarian cancer. The New England Journal of Medicine. 322: 89-94. PMID 2152972 DOI: 10.1056/Nejm199001113220204  0.531
1990 Verhaagen J, Oestreicher AB, Grillo M, Khew-Goodall YS, Gispen WH, Margolis FL. Neuroplasticity in the olfactory system: differential effects of central and peripheral lesions of the primary olfactory pathway on the expression of B-50/GAP43 and the olfactory marker protein. Journal of Neuroscience Research. 26: 31-44. PMID 2141653 DOI: 10.1002/Jnr.490260105  0.637
1989 Hesselmans LF, Jennekens FG, van den Oord CJ, Oestreicher AB, Veldman H, Gispen WH. A light and electron microscopical study of B-50 (GAP-43) in human intramuscular nerve and neuromuscular junctions during development. Journal of the Neurological Sciences. 89: 301-11. PMID 2926454 DOI: 10.1016/0022-510X(89)90031-2  0.546
1989 Verhaagen J, Oestreicher AB, Gispen WH, Margolis FL. The expression of the growth associated protein B50/GAP43 in the olfactory system of neonatal and adult rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 9: 683-91. PMID 2918383 DOI: 10.1523/Jneurosci.09-02-00683.1989  0.652
1989 Van der Zee CE, Nielander HB, Vos JP, Lopes da Silva S, Verhaagen J, Oestreicher AB, Schrama LH, Schotman P, Gispen WH. Expression of growth-associated protein B-50 (GAP43) in dorsal root ganglia and sciatic nerve during regenerative sprouting. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 9: 3505-12. PMID 2552034 DOI: 10.1523/Jneurosci.09-10-03505.1989  0.697
1989 de Koning P, Verhaagen J, Sloot W, Jennekens FG, Gispen WH. Org.2766 stimulates collateral sprouting in the soleus muscle of the rat following partial denervation. Muscle & Nerve. 12: 353-9. PMID 2542784 DOI: 10.1002/Mus.880120503  0.712
1988 Verhaagen J, Oesteicher AB, Edwards PM, Veldman H, Jennekens FG, Gispen WH. Light- and electron-microscopical study of phosphoprotein B-50 following denervation and reinnervation of the rat soleus muscle. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 8: 1759-66. PMID 2966853 DOI: 10.1523/Jneurosci.08-05-01759.1988  0.752
1988 Gerritsen van der Hoop R, de Koning P, Boven E, Neijt JP, Jennekens FG, Gispen WH. Efficacy of the neuropeptide ORG.2766 in the prevention and treatment of cisplatin-induced neurotoxicity in rats. European Journal of Cancer & Clinical Oncology. 24: 637-42. PMID 2838292 DOI: 10.1016/0277-5379(88)90293-3  0.537
1988 Verhaagen J, Edwards PM, Gispen WH. Damaged rat peripheral nerves do not contain detectable amounts of alpha-MSH. Journal of Neuroscience Research. 19: 14-8. PMID 2830414 DOI: 10.1002/jnr.490190103  0.649
1988 Hoop RGvd, Neijt J, Jennekens F, Gispen W, Bär P, Wokke J, Jennekens F. Scientific meeting of the Amsterdamsche Neurologenvereeniging held in Amsterdam, 3rd December 1987 Clinical Neurology and Neurosurgery. 90: 183-184. DOI: 10.1016/S0303-8467(88)80047-7  0.583
1987 De Koning P, Neijt JP, Jennekens FG, Gispen WH. Evaluation of cis-diamminedichloroplatinum (II) (cisplatin) neurotoxicity in rats. Toxicology and Applied Pharmacology. 89: 81-7. PMID 3590191 DOI: 10.1016/0041-008X(87)90178-5  0.555
1987 de Koning P, Neijt JP, Jennekens FG, Gispen WH. Org.2766 protects from cisplatin-induced neurotoxicity in rats. Experimental Neurology. 97: 746-50. PMID 3040462 DOI: 10.1016/0014-4886(87)90132-4  0.562
1987 Gispen WH, De Koning P, Kuiters RR, Van der Zee CE, Verhaagen J. On the neurotrophic action of melanocortins. Progress in Brain Research. 72: 319-31. PMID 3039580 DOI: 10.1016/S0079-6123(08)60218-6  0.588
1987 Verhaagen J, Edwards PM, Jennekens FG, Schotman P, Gispen WH. Early effect of an ACTH4-9 analog (Org.2766) on regenerative sprouting demonstrated by the use of neurofilament-binding antibodies isolated from a serum raised by alpha-MSH immunization. Brain Research. 404: 142-50. PMID 3032330 DOI: 10.1016/0006-8993(87)91365-5  0.723
1987 Verhaagen J, Edwards PM, Jennekens FG, Gispen WH. Pharmacological aspects of the influence of melanocortins on the formation of regenerative peripheral nerve sprouts. Peptides. 8: 581-4. PMID 2819831 DOI: 10.1016/0196-9781(87)90028-3  0.745
1987 Dekker A, Gispen WH, de Wied D. Axonal regeneration, growth factors and neuropeptides. Life Sciences. 41: 1667-78. PMID 2443782  0.56
1986 Verhaagen J, Edwards PM, Jennekens FG, Schotman P, Gispen WH. Alpha-melanocyte-stimulating hormone stimulates the outgrowth of myelinated nerve fibers after peripheral nerve crush. Experimental Neurology. 92: 451-4. PMID 3956675 DOI: 10.1016/0014-4886(86)90098-1  0.738
1986 Gispen WH, Isaacson RL, Spruijt BM, de Wied D. Melanocortins, neural plasticity and aging. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 10: 415-26. PMID 3025925 DOI: 10.1016/0278-5846(86)90015-1  0.567
1986 Verhaagen J, van Hooff CO, Edwards PM, De Graan PN, Oestreicher AB, Schotman P, Jennekens FG, Gispen WH. The kinase C substrate protein B-50 and axonal regeneration. Brain Research Bulletin. 17: 737-41. PMID 2948616 DOI: 10.1016/0361-9230(86)90084-5  0.745
1986 Verhaagen J, Edwards PM, Schotman P, Jennekens FG, Gispen WH. Characterization of epitopes shared by alpha-melanocyte-stimulating hormone (alpha-MSH) and the 150-kD neurofilament protein (NF150): relationship to neurotrophic sequences. Journal of Neuroscience Research. 16: 589-600. PMID 2432275 DOI: 10.1002/jnr.490160402  0.703
1984 Edwards PM, Van der Zee CE, Verhaagen J, Schotman P, Jennekens FG, Gispen WH. Evidence that the neurotrophic actions of alpha-MSH may derive from its ability to mimick the actions of a peptide formed in degenerating nerve stumps. Journal of the Neurological Sciences. 64: 333-40. PMID 6432963 DOI: 10.1016/0022-510X(84)90181-3  0.739
1984 Bijlsma WA, Jennekens FG, Schotman P, Gispen WH. Neurotrophic factors and regeneration in the peripheral nervous system. Psychoneuroendocrinology. 9: 199-215. PMID 6093175 DOI: 10.1016/0306-4530(84)90001-5  0.53
1983 Bijlsma WA, van Asselt E, Veldman H, Jennekens FG, Schotman P, Gispen WH. Ultrastructural study of effect of ACTH4-10 on nerve regeneration; axons become larger in number and smaller in diameter. Acta Neuropathologica. 62: 24-30. PMID 6318504 DOI: 10.1007/Bf00684916  0.565
1983 Bijlsma WA, Schotman P, Jennekens FG, Gispen WH. Regeneration and protein synthesis in the spinal cord: the influence of ACTH-like peptides on cell-free protein synthesis. Neuroscience Letters. 38: 297-302. PMID 6314188 DOI: 10.1016/0304-3940(83)90385-3  0.579
1983 Bijlsma WA, Schotman P, Jennekens FG, Gispen WH, De Wied D. The enhanced recovery of sensorimotor function in rats is related to the melanotropic moiety of ACTH/MSH neuropeptides. European Journal of Pharmacology. 92: 231-6. PMID 6313395 DOI: 10.1016/0014-2999(83)90291-1  0.727
1983 Bijlsma WA, Jennekens FG, Schotman P, Gispen WH. Stimulation by ACTH4-10 of nerve fiber regeneration following sciatic nerve crush. Muscle & Nerve. 6: 104-12. PMID 6304506 DOI: 10.1002/Mus.880060205  0.547
1983 Drago F, Bohus B, Gispen WH, Scapagnini U, De Wied D. Prolactin-enhanced grooming behavior: interaction with ACTH. Brain Research. 263: 277-82. PMID 6301648 DOI: 10.1016/0006-8993(83)90320-7  0.591
1982 Zwiers H, Jolles J, Aloyo VJ, Oestreicher AB, Gispen WH. ACTH and synaptic membrane phosphorylation in rat brain. Progress in Brain Research. 56: 405-17. PMID 6298877 DOI: 10.1016/S0079-6123(08)63787-5  0.567
1982 Jolles J, van Dongen CJ, ten Haaf J, Gispen WH. Polyphosphoinositide metabolism in rat brain: effects of neuropeptides, neurotransmitters and cyclic nucleotides. Peptides. 3: 709-14. PMID 6129617  0.576
1981 Bijlsma WA, Jennekens FG, Schotman P, Gispen WH. Effects of corticotrophin (ACTH) on recovery of sensorimotor function in the rat: structure-activity study. European Journal of Pharmacology. 76: 73-9. PMID 6274673 DOI: 10.1016/0014-2999(81)90011-X  0.592
1981 Jolles J, Zwiers H, Dekker A, Wirtz KW, Gispen WH. Corticotropin-(1--24)-tetracosapeptide affects protein phosphorylation and polyphosphoinositide metabolism in rat brain. The Biochemical Journal. 194: 283-91. PMID 6272727 DOI: 10.1042/Bj1940283  0.56
1981 Jolles J, Schrama LH, Gispen WH. Calcium-dependent turnover of brain polyphosphoinositides in vitro after prelabelling in vivo. Biochimica Et Biophysica Acta. 666: 90-8. PMID 6271236  0.577
1981 Jolles J, Bär PR, Gispen WH. Modulation of brain polyphosphoinositide metabolism by ACTH and beta-endorphin: structure-activity studies. Brain Research. 224: 315-26. PMID 6269709  0.569
1981 van Ree JM, Bohus B, Csontos KM, Gispen WH, Greven HM, Nijkamp FP, Opmeer FA, de Rotte GA, van Wimersma Greidanus TB, Witter A, de Wied D. Gamma-melanotropin and brain function. Ciba Foundation Symposium. 81: 263-76. PMID 6268381  0.71
1981 van Ree JM, Bohus B, Csontos KM, Gispen WH, Greven HM, Nijkamp FP, Opmeer FA, de Rotte GA, van Wimersma Greidanus TB, Witter A, de Wied D. Behavioral profile of gamma-MSH: relationship with ACTH and beta-endorphin action. Life Sciences. 28: 2875-8. PMID 6267399 DOI: 10.1016/0024-3205(81)90104-1  0.709
1980 Rees HD, Verhoef J, Witter A, Gispen WH, de Wied D. Autoradiographic studies with a behaviorally potent 3H-ACTH4--9 analog in the brain after intraventricular injection in rats. Brain Research Bulletin. 5: 509-14. PMID 6253028  0.604
1980 Jolles J, Zwiers H, van Dongen CJ, Schotman P, Wirtz KW, Gispen WH. Modulation of brain polyphosphoinositide metabolism by ACTH-sensitive protein phosphorylation. Nature. 286: 623-5. PMID 6250080 DOI: 10.1038/286623A0  0.559
1980 Gispen WH, Ormond D, ten Haaf J, De Wied D. Modulation of ACTH-induced grooming by [Des-Tyr1]-gamma-endorphin and haloperidol. European Journal of Pharmacology. 63: 203-7. PMID 6247168  0.573
1980 Verhoef J, Loeber JG, Burbach JP, Gispen WH, Witter A, de Wied D. Alpha-endorphin, gamma-endorphin and their des-tyrosine fragments in rat pituitary and brain tissue. Life Sciences. 26: 851-9. PMID 6154859 DOI: 10.1016/0024-3205(80)90347-1  0.579
1980 Gispen WH, de Wied D. ACTH as neuromodulator: behavioral and neurochemical aspects. Progress in Clinical and Biological Research. 39: 251-63. PMID 6105672  0.523
1979 Wiegant VM, Jolles J, Colbern DL, Zimmermann E, Gispen WH. Intracerebroventricular ACTH activates the pituitary-adrenal system:dissociation from a behavioral response. Life Sciences. 25: 1791-6. PMID 231165  0.539
1979 Jolles J, Wirtz KW, Schotman P, Gispen WH. Pituitary hormones influence polyphosphoinositide metabolism in rat brain. Febs Letters. 105: 110-4. PMID 226403 DOI: 10.1016/0014-5793(79)80897-2  0.58
1979 Jolles J, Rompa-Barendregt J, Gispen WH. ACTH-induced excessive grooming in the rat: the influence of environmental and motivational factors. Hormones and Behavior. 12: 60-72. PMID 225257  0.571
1979 Jolles J, Rompa-Barendregt J, Gispen W. Novelty and grooming behavior in the rat Behavioral and Neural Biology. 25: 563-572. DOI: 10.1016/S0163-1047(79)90362-5  0.564
1978 Jolles J, Wiegant VM, Gispen WH. Reduced behavioral effectiveness of ACTH(1-24) after a second administration: interaction with opiates. Neuroscience Letters. 9: 261-6. PMID 19605229  0.56
1978 Reith ME, Schotman P, Gispen WH. Measurements of in vivo rates of protein synthesis in brain, spinal cord, heart and liver of young versus adult rats, intact versus hypophysectomized rats. Journal of Neurochemistry. 30: 587-94. PMID 681932 DOI: 10.1111/j.1471-4159.1978.tb07812.x  0.536
1978 Wiegant VM, Colbern D, Van Wimersma Greidanus TB, Gispen WH. Differential behavioral effects of ACTH 4-10 and [D-Phe7]ACTH 4-10 Brain Research Bulletin. 3: 167-170. PMID 206319 DOI: 10.1016/0361-9230(78)90042-4  0.579
1978 SCHOTMAN P, GIPON L, JENNEKENS FG, GISPEN WH. POLYNEUROPATHIES AND CNS PROTEIN METABOLISM Journal of Neuropathology and Experimental Neurology. 37: 820-837. DOI: 10.1097/00005072-197811000-00008  0.523
1977 Schotman P, Reith ME, Gispen WH. Effects of stressful procedures as ether anesthesia and intracranial injections on amino acid incorporation into brain protein. Brain Research Bulletin. 2: 83-7. PMID 880489 DOI: 10.1016/0361-9230(77)90002-8  0.528
1977 Gispen WH, Reith ME, Schotman P, Wiegant VM, Zwiers H, de Wied D. CNS and ACTH-like peptides: neurochemical response and interaction with opiates. Advances in Biochemical Psychopharmacology. 17: 61-80. PMID 200081  0.686
1977 Wiegant VM, Gispen WH, Terenius L, de Wied D. ACTH-like peptides and morphine: interaction at the level of the CNS. Psychoneuroendocrinology. 2: 63-70. PMID 198834  0.564
1977 Gispen WH, van Ree JM, de Wied D. Lipotropin and the central nervous system. International Review of Neurobiology. 20: 209-50. PMID 22510  0.558
1977 Reith M, Schotman P, Gispen W, de Wied D. Pituitary peptides as modulators of neural functioning Trends in Biochemical Sciences. 2: 56-58. DOI: 10.1016/0968-0004(77)90095-0  0.555
1976 De Wied D, Gispen WH. Impaired development of tolerance to morphine analgesia in rats with hereditary diabetes insipidus. Psychopharmacologia. 46: 27-9. PMID 1257364 DOI: 10.1007/BF00421545  0.573
1976 de Wied D, van Wimersma Greidanus TB, Bohus B, Urban I, Gispen WH. Vasopressin and memory consolidation. Progress in Brain Research. 45: 181-94. PMID 1013337 DOI: 10.1016/S0079-6123(08)60990-5  0.654
1976 Gispen WH, Wiegant VM, Bradbury AF, Hulme EC, Smyth DG, Snell CR, de Wied D. Induction of excessive grooming in the rat by fragments of lipotropin. Nature. 264: 794-5. PMID 189197 DOI: 10.1038/264794A0  0.614
1976 Gispen WH, Buitelaar J, Wiegant VM, Terenius L, De Wied D. Interaction between ACTH fragments, brain opiate receptors and morphine-induced analgesia. European Journal of Pharmacology. 39: 393-7. PMID 185067  0.584
1975 Reith ME, Schotman P, Gispen WH. The neurotropic action of ACTH: effects of ACTH-like peptides on the incorporation of leucine into protein of brain stem slices from hypophysectomized rats. Neuroscience Letters. 1: 55-9. PMID 19604752 DOI: 10.1016/0304-3940(75)90012-9  0.569
1975 Gispen WH, Krivoy WA, de Wied D, Zimmermann E. Effect of rifampicin on development of tolerance to analgesic actions. Life Sciences. 17: 247-51. PMID 1160497  0.527
1975 Terenius L, Gispen WH, De Wied D. ACTH-like peptides and opiate receptors in the rat brain: structure-activity studies. European Journal of Pharmacology. 33: 395-9. PMID 241656 DOI: 10.1016/0014-2999(75)90185-5  0.592
1975 Reith ME, Schotman P, Gispen WH. Effects of behaviorally active ACTH analogs on brain protein metabolism. Progress in Brain Research. 42: 195-200. PMID 172963 DOI: 10.1016/S0079-6123(08)63660-2  0.51
1975 Gispen WH, Wiegant VM, Greven HM, de Wied D. The induction of excessive grooming in the rat by intraventricular application of peptides derived from ACTH: structure-activity studies. Life Sciences. 17: 645-52. PMID 171535  0.588
1975 Gispen WH, Van Wimersma Greidanus TB, Waters-Ezrin C, Zimmermann E, Krivoy WA, De Wied D. Influence of peptides on reduced response of rats to electric footshock after acute administration of morphine. European Journal of Pharmacology. 33: 99-105. PMID 170120 DOI: 10.1016/0014-2999(75)90143-0  0.711
1974 Reith ME, Schotman P, Gispen WH. Hypophysectomy, ACTH1-10 and in vitro protein synthesis in rat brain stem slices. Brain Research. 81: 571-5. PMID 4373137 DOI: 10.1016/0006-8993(74)90855-5  0.541
1973 Bohus B, Gispen WH, De Wied D. Effect of lysine vasopressin and ACTH 4-10 on conditioned avoidance behavior of hypophysectomized rats. Neuroendocrinology. 11: 137-43. PMID 4349360 DOI: 10.1159/000122126  0.571
1972 Schotman P, Gispen WH, Jansz HS, De Wied D. Effects of ACTH analogues on macromolecule metabolism in the brain stem of hypophysectomized rats. Brain Research. 46: 349-62. PMID 4344078 DOI: 10.1016/0006-8993(72)90025-X  0.699
1972 Versteeg DH, Gispen WH, Schotmann P, Witter A, de Wied D. Hypophysectomy and rat brain metabolism: effects of synthetic ACTH analogs. Advances in Biochemical Psychopharmacology. 6: 219-39. PMID 4341334  0.578
1971 Gispen WH, de Wied D, Schotman P, Jansz HS. Brain stem polysomes and avoidance performance of hypophysectomized rats subjected to peptide treatment. Brain Research. 31: 341-51. PMID 4328057 DOI: 10.1016/0006-8993(71)90187-9  0.707
1970 Gispen WH, de Wied D, Schotman P, Jansz HS. On the relationship between the deficient performance of hypophysectomized rats in shuttle-box conditioning and the RNA metabolism in their brain stem. Brain Research. 24: 551. PMID 5494550  0.686
1970 Gispen WH, de Wied D, Schotman P, Jansz HS. Effects of hypophysectomy on RNA metabolism in rat brain stem. Journal of Neurochemistry. 17: 751-61. PMID 4987663 DOI: 10.1111/J.1471-4159.1970.Tb03345.X  0.682
1970 Gispen WH, v Wimersma Greidanus TB, de Wied D. Effects of hypophysectomy and ACTH 1-10 on responsiveness to electric shock in rats. Physiology & Behavior. 5: 143-6. PMID 4337772  0.564
Low-probability matches (unlikely to be authored by this person)
1996 Maaswinkel H, Gispen WH, Spruijt BM. Effects of an electrolytic lesion of the prelimbic area on anxiety-related and cognitive tasks in the rat. Behavioural Brain Research. 79: 51-9. PMID 8883816 DOI: 10.1016/0166-4328(95)00261-8  0.29
1991 Van der Zee CE, Brakkee JH, Gispen WH. Putative neurotrophic factors and functional recovery from peripheral nerve damage in the rat. British Journal of Pharmacology. 103: 1041-6. PMID 1678980  0.289
1989 Schmidt-Michels M, Edwards PM, Oestreicher AB, Gispen WH. Colchicine effect on B-50/GAP43 phosphoprotein localization in rat dorsal root ganglion explants. Neuroscience Letters. 97: 285-90. PMID 2717063 DOI: 10.1016/0304-3940(89)90612-5  0.286
1996 Sigling HO, Gispen W, van Engeland H, Spruijt BM. The development of home-seeking behavior in rat pups European Neuropsychopharmacology. 6: S4-154-S4-155. DOI: 10.1016/0924-977X(96)83121-X  0.284
1996 Hens JJ, Oestreicher AB, De Wit M, Marquart A, Gispen WH, De Graan PN. Evidence for a role of calmodulin in calcium-induced noradrenaline release from permeated synaptosomes: effects of calmodulin antibodies and antagonists. Journal of Neurochemistry. 66: 1933-42. PMID 8780020 DOI: 10.1046/J.1471-4159.1996.66051933.X  0.274
1996 Verkade P, Verkleij AJ, Annaert WG, Gispen WH, Oestreicher AB. Ultrastructural localization of B-50/growth-associated protein-43 to anterogradely transported synaptophysin-positive and calcitonin gene-related peptide-negative vesicles in the regenerating rat sciatic nerve. Neuroscience. 71: 489-505. PMID 9053802 DOI: 10.1016/0306-4522(95)00463-7  0.274
1996 van Rijzingen IM, van Doremalen E, Gispen WH, Spruijt BM. Long-term impoverished housing effects on Morris maze performance after a fimbria lesion. Behavioural Brain Research. 77: 149-54. PMID 8762165 DOI: 10.1016/0166-4328(95)00210-3  0.271
1990 Sporel-Ozakat RE, Edwards PM, Van der Hoop RG, Gispen WH. An ACTH-(4-9) analogue, Org 2766, improves recovery from acrylamide neuropathy in rats. European Journal of Pharmacology. 186: 181-7. PMID 1963145  0.27
1985 de Graan PN, van Hooff CO, Tilly BC, Oestreicher AB, Schotman P, Gispen WH. Phosphoprotein B-50 in nerve growth cones from fetal rat brain. Neuroscience Letters. 61: 235-41. PMID 2934647 DOI: 10.1016/0304-3940(85)90470-7  0.269
1997 de Groot JC, Hamers FP, Gispen WH, Smoorenburg GF. Co-administration of the neurotrophic ACTH(4-9) analogue, ORG 2766, may reduce the cochleotoxic effects of cisplatin. Hearing Research. 106: 9-19. PMID 9112103 DOI: 10.1016/S0378-5955(96)00213-4  0.265
1998 Schaaper WMM, Adan RAH, Posthuma TA, Oosterom J, Gispen WH, Meloen RH. Synthesis of cyclic α-MSH peptides Letters in Peptide Science. 5: 205-208. DOI: 10.1023/A:1008877507882  0.265
1994 Schipper N, Verhoef J, Romeijn S, Brakkee J, Wiegant V, Gispen W, Merkus F. P21 Nasal absorption of an ACTH(4–9) peptide analogue and its effect on peripheral nerve regeneration in rats Journal of Controlled Release. 29: 394-395. DOI: 10.1016/0168-3659(94)90103-1  0.26
1996 Maaswinkel H, Baars AM, Gispen WH, Spruijt BM. Roles of the basolateral amygdala and hippocampus in social recognition in rats. Physiology & Behavior. 60: 55-63. PMID 8804643 DOI: 10.1016/0031-9384(95)02233-3  0.259
1991 Edwards PM, Sporel-Ozakat E, Gispen WH. Neurotoxic acrylamide and neurotrophic melanocortin peptides--can contrasting actions provide clues about modes of action? Neuropathology and Applied Neurobiology. 17: 91-104. PMID 1857491  0.257
1995 Alonso G, Ridet JL, Oestreicher AB, Gispen WH, Privat A. B-50 (GAP-43) immunoreactivity is rarely detected within intact catecholaminergic and serotonergic axons innervating the brain and spinal cord of the adult rat, but is associated with these axons following lesion. Experimental Neurology. 134: 35-48. PMID 7545587 DOI: 10.1006/exnr.1995.1034  0.257
1996 Verkade P, Verkleij AJ, Gispen WH, Oestreicher AB. Ultrastructural evidence for the lack of co-transport of B-50/GAP-43 and calmodulin in myelinated axons of the regenerating rat sciatic nerve. Journal of Neurocytology. 25: 583-95. PMID 8971638  0.255
2000 Ramakers GM, Heinen K, Gispen WH, de Graan PN. Long term depression in the CA1 field is associated with a transient decrease in pre- and postsynaptic PKC substrate phosphorylation. The Journal of Biological Chemistry. 275: 28682-7. PMID 10867003 DOI: 10.1074/Jbc.M003068200  0.254
1991 Van Lookeren Campagne M, Oestreicher AB, Buma P, Verkleij AJ, Gispen WH. Ultrastructural localization of adrenocorticotrophic hormone and the phosphoprotein B-50/growth-associated protein 43 in freeze-substituted, Lowicryl HM20-embedded mesencephalic central gray substance of the rat. Neuroscience. 42: 517-29. PMID 1716747  0.254
1992 Stecher B, Hens JJ, Weller U, Gratzl M, Gispen WH, De Graan PN. Noradrenaline release from permeabilized synaptosomes is inhibited by the light chain of tetanus toxin. Febs Letters. 312: 192-4. PMID 1426251 DOI: 10.1016/0014-5793(92)80933-8  0.253
1987 De Koning P, Gispen WH. Org.2766 improves functional and electrophysiological aspects of regenerating sciatic nerve in the rat. Peptides. 8: 415-22. PMID 2821519 DOI: 10.1016/0196-9781(87)90003-9  0.252
1988 Gispen WH, Colbern DL, Spruijt BM. Molecular transduction mechanisms in ACTH-induced grooming. Psychopharmacology Series. 4: 215-31. PMID 2839822 DOI: 10.1007/978-3-642-73223-2_16  0.249
1995 Alonso G, Oestreicher AB, Gispen WH, Privat A. Immunolocalization of B-50 (GAP-43) in intact and lesioned neurohypophysis of adult rats. Experimental Neurology. 131: 93-107. PMID 7895816 DOI: 10.1016/0014-4886(95)90011-X  0.244
2003 Vogelaar CF, Hoekman MF, Gispen WH, Burbach JP. Homeobox gene expression in adult dorsal root ganglia during sciatic nerve regeneration: is regeneration a recapitulation of development? European Journal of Pharmacology. 480: 233-50. PMID 14623366 DOI: 10.1016/j.ejphar.2003.08.110  0.244
2000 Ramakers GM, Pasinelli P, van Beest M, van der Slot A, Gispen WH, De Graan PN. Activation of pre- and postsynaptic protein kinase C during tetraethylammonium-induced long-term potentiation in the CA1 field of the hippocampus. Neuroscience Letters. 286: 53-6. PMID 10822151 DOI: 10.1016/S0304-3940(00)01081-8  0.242
1997 Verkade P, Schrama LH, Verkleij AJ, Gispen WH, Oestreicher AB. Ultrastructural co-localization of calmodulin and B-50/growth-associated protein-43 at the plasma membrane of proximal unmyelinated axon shafts studied in the model of the regenerating rat sciatic nerve. Neuroscience. 79: 1207-18. PMID 9219979 DOI: 10.1016/S0306-4522(97)00041-9  0.242
1985 Gispen WH, Leunissen JL, Oestreicher AB, Verkleij AJ, Zwiers H. Presynaptic localization of B-50 phosphoprotein: the (ACTH)-sensitive protein kinase substrate involved in rat brain polyphosphoinositide metabolism. Brain Research. 328: 381-5. PMID 2985187 DOI: 10.1016/0006-8993(85)91054-6  0.241
1996 Verzè L, Buffo A, Rossi F, Oestreicher AB, Gispen WH, Strata P. Increase of B-50/GAP-43 immunoreactivity in uninjured muscle nerves of MDX mice. Neuroscience. 70: 807-15. PMID 9045090 DOI: 10.1016/S0306-4522(96)83017-X  0.241
1989 Van der Zee CE, Van der Hoop RG, Gispen WH. Beneficial effect of Org 2766 in treatment of peripheral neuropathy in streptozocin-induced diabetic rats. Diabetes. 38: 225-30. PMID 2536628 DOI: 10.2337/diab.38.2.225  0.24
1995 Verkade P, Oestreicher AB, Verkleij AJ, Gispen WH. The increase in B-50/GAP-43 in regenerating rat sciatic nerve occurs predominantly in unmyelinated axon shafts: a quantitative ultrastructural study. The Journal of Comparative Neurology. 356: 433-43. PMID 7642804 DOI: 10.1002/cne.903560310  0.24
2009 Gispen WH, Wiegant VM. Opiate antagonists suppress ACTH(1-24)-induced excessive grooming in the rat. Neuroscience Letters. 2: 159-64. PMID 19604834 DOI: 10.1016/0304-3940(76)90008-2  0.24
1988 van der Zee CE, Schuurman T, Traber J, Gispen WH. Oral administration of nimodipine accelerates functional recovery following peripheral nerve damage in the rat. Neuroscience Letters. 83: 143-8. PMID 3441293 DOI: 10.1016/0304-3940(87)90231-X  0.239
1994 Kappelle AC, Biessels G, Brakkee JH, Gispen WH. Influence of dihydropyridines on the recovery of sensory function after a caudal nerve crush in the rat. Restorative Neurology and Neuroscience. 6: 271-6. PMID 21551757 DOI: 10.3233/RNN-1994-6402  0.237
1990 Spruijt B, Pitsikas N, Algeri S, Gispen WH. Org2766 improves performance of rats with unilateral lesions in the fimbria fornix in a spatial learning task. Brain Research. 527: 192-7. PMID 2174715 DOI: 10.1016/0006-8993(90)91137-6  0.235
1997 van Meeteren NL, Brakkee JH, Helders PJ, Croiset G, Gispen WH, Wiegant VM. Recovery of function after sciatic nerve crush lesion in rats selected for diverging locomotor activity in the open field. Neuroscience Letters. 238: 131-4. PMID 9464637 DOI: 10.1016/S0304-3940(97)00870-7  0.235
1991 Hamers FP, van der Hoop RG, Steerenburg PA, Neijt JP, Gispen WH. Putative neurotrophic factors in the protection of cisplatin-induced peripheral neuropathy in rats. Toxicology and Applied Pharmacology. 111: 514-22. PMID 1660632  0.234
1992 Jap Tjoen San ER, Schmidt-Michels M, Oestreicher AB, Gispen WH, Schotman P. Inhibition of nerve growth factor-induced B-50/GAP-43 expression by antisense oligomers interferes with neurite outgrowth of PC12 cells. Biochemical and Biophysical Research Communications. 187: 839-46. PMID 1388357  0.234
1986 De Koning P, Brakkee JH, Gispen WH. Methods for producing a reproducible crush in the sciatic and tibial nerve of the rat and rapid and precise testing of return of sensory function. Beneficial effects of melanocortins. Journal of the Neurological Sciences. 74: 237-46. PMID 3016200 DOI: 10.1016/0022-510X(86)90109-7  0.233
1988 Gorgels TG, Oestreicher AB, de Kort EJ, Gispen WH. Immunocytochemical distribution of the protein kinase C substrate B-50 (GAP43) in developing rat pyramidal tract. Neuroscience Letters. 83: 59-64. PMID 3441300 DOI: 10.1016/0304-3940(87)90216-3  0.231
1992 Janssen U, Richter-Landsberg C, Oestreicher AB, De Graaf PN, Gispen WH, Flohr H. Identification of a B-50-like protein in frog brain synaptosomes. Brain Research. 570: 21-6. PMID 1535531  0.229
1988 Van der Zee CE, Brakkee JH, Gispen WH. alpha-MSH and Org.2766 in peripheral nerve regeneration: different routes of delivery. European Journal of Pharmacology. 147: 351-7. PMID 2837394 DOI: 10.1016/0014-2999(88)90168-9  0.228
1979 Wiegant VM, Dunn AJ, Schotman P, Gispen WH. ACTH-like neurotropic peptides: possible regulators of rat brain cyclic AMP. Brain Research. 168: 565-84. PMID 219939 DOI: 10.1016/0006-8993(79)90310-X  0.228
1999 van der Kraan M, Tatro JB, Entwistle ML, Brakkee JH, Burbach JP, Adan RA, Gispen WH. Expression of melanocortin receptors and pro-opiomelanocortin in the rat spinal cord in relation to neurotrophic effects of melanocortins. Brain Research. Molecular Brain Research. 63: 276-86. PMID 9878783 DOI: 10.1016/S0169-328X(98)00291-5  0.228
2003 Ter Laak MP, Brakkee JH, Adan RA, Hamers FP, Gispen WH. The potent melanocortin receptor agonist melanotan-II promotes peripheral nerve regeneration and has neuroprotective properties in the rat. European Journal of Pharmacology. 462: 179-83. PMID 12591111 DOI: 10.1016/S0014-2999(02)02945-X  0.227
1986 Van Hooff CO, De Graan PN, Boonstra J, Oestreicher AB, Schmidt-Michels MH, Gispen WH. Nerve growth factor enhances the level of the protein kinase C substrate B-50 in pheochromocytoma PC12 cells. Biochemical and Biophysical Research Communications. 139: 644-51. PMID 3533064 DOI: 10.1016/S0006-291X(86)80039-0  0.224
1986 Edwards PM, Kuiters RR, Boer GJ, Gispen WH. Recovery from peripheral nerve transection is accelerated by local application of alpha-MSH by means of microporous Accurel polypropylene tubes. Journal of the Neurological Sciences. 74: 171-6. PMID 3734835 DOI: 10.1016/0022-510X(86)90102-4  0.224
1989 van der Hoop RG, Brakkee JH, Kapelle A, Samson M, de Koning P, Gispen WH. A new approach for the evaluation of recovery after peripheral nerve damage. Journal of Neuroscience Methods. 26: 111-6. PMID 2851075 DOI: 10.1016/0165-0270(88)90159-8  0.222
1989 Van Hooff CO, Holthuis JC, Oestreicher AB, Boonstra J, De Graan PN, Gispen WH. Nerve growth factor-induced changes in the intracellular localization of the protein kinase C substrate B-50 in pheochromocytoma PC12 cells. The Journal of Cell Biology. 108: 1115-25. PMID 2537833 DOI: 10.1083/JCB.108.3.1115  0.222
1991 Di Luca M, Cimino M, De Graan PN, Oestreicher AB, Gispen WH, Cattabeni F. Microencephaly reduces the phosphorylation of the PKC substrate B-50/GAP43 in rat cortex and hippocampus. Brain Research. 538: 95-101. PMID 1826859  0.221
1991 Sporel-Ozakat RE, Edwards PM, Hepgul KT, Savas A, Gispen WH. A simple method for reducing autotomy in rats after peripheral nerve lesions. Journal of Neuroscience Methods. 36: 263-5. PMID 2062121  0.221
2000 ter Laak MP, Hamers FP, Kirk CJ, Gispen WH. rhGGF2 protects against cisplatin-induced neuropathy in the rat. Journal of Neuroscience Research. 60: 237-44. PMID 10740229 DOI: 10.1002/(SICI)1097-4547(20000415)60:2<237::AID-JNR13>3.0.CO;2-5  0.221
1989 Van der Neut R, Bär PR, Sodaar P, Gispen WH. Trophic influences of alpha-MSH and ACTH4-10 on neuronal outgrowth in vitro. Peptides. 9: 1015-20. PMID 2854241 DOI: 10.1016/0196-9781(88)90082-4  0.221
1981 Zwiers H, Aloyo VJ, Gispen WH. Behavioral and neurochemical effects of the new opioid peptide dynorphin-(1-13): comparison with other neuropeptides Life Sciences. 28: 2545-2551. PMID 6265732 DOI: 10.1016/0024-3205(81)90597-X  0.217
1996 Ramakers G, Gispen W, DeGraan P. Changes in pre- and postsynaptic PKC substrate phosphorylation after mGluR stimulation and LTD induction Neuropharmacology. 35. DOI: 10.1016/0028-3908(96)84741-1  0.216
1990 van der Neut R, Oestreicher AB, Gispen WH, Bär PR. The expression of B-50/GAP-43 during development of rat spinal neurons in culture is regulated by interneuronal contact. Neuroscience Letters. 109: 36-41. PMID 2138260 DOI: 10.1016/0304-3940(90)90534-G  0.216
1991 Gispen WH, Nielander HB, De Graan PN, Oestreicher AB, Schrama LH, Schotman P. Role of the growth-associated protein B-50/GAP-43 in neuronal plasticity. Molecular Neurobiology. 5: 61-85. PMID 1840422  0.216
1999 Lankhorst AJ, Duis SE, ter Laak MP, Joosten EA, Hamers FP, Gispen WH. Functional recovery after central infusion of alpha-melanocyte-stimulating hormone in rats with spinal cord contusion injury. Journal of Neurotrauma. 16: 323-31. PMID 10225218  0.216
1992 van Lookeren Campagne M, Dotti CG, Verkleij AJ, Gispen WH, Oestreicher AB. Redistribution of B-50/growth-associated protein 43 during differentiation and maturation of rat hippocampal neurons in vitro. Neuroscience. 51: 601-19. PMID 1336822 DOI: 10.1016/0306-4522(92)90300-Q  0.216
1990 Van Lookeren Campagne M, Oestreicher AB, Van Bergen en Henegouwen PM, Gispen WH. Ultrastructural double localization of B-50/GAP43 and synaptophysin (p38) in the neonatal and adult rat hippocampus. Journal of Neurocytology. 19: 948-61. PMID 2149862  0.214
1996 Biewenga JE, Schrama LH, Gispen WH. Presynaptic phosphoprotein B-50/GAP-43 in neuronal and synaptic plasticity. Acta Biochimica Polonica. 43: 327-38. PMID 8862178  0.214
1992 Jap Tjoen San ER, Schmidt-Michels M, Oestreicher AB, Schotman P, Gispen WH. Dexamethasone-induced effects on B-50/GAP-43 expression and neurite outgrowth in PC12 cells. Journal of Molecular Neuroscience : Mn. 3: 189-95. PMID 1389999  0.211
1998 Aarts LH, Schrama LH, Hage WJ, Bos JL, Gispen WH, Schotman P. B-50/GAP-43-induced formation of filopodia depends on Rho-GTPase. Molecular Biology of the Cell. 9: 1279-92. PMID 9614174 DOI: 10.1091/Mbc.9.6.1279  0.211
1999 Joosten EA, Majewska B, Houweling DA, Bär PR, Gispen WH. Alpha-melanocyte stimulating hormone promotes regrowth of injured axons in the adult rat spinal cord. Journal of Neurotrauma. 16: 543-53. PMID 10391370  0.21
1991 Pitsikas N, Spruijt BM, Josephy M, Algeri S, Gispen WH. Effect of Org2766, an ACTH(4-9) analogue, on recovery after bilateral transection of the fimbria fornix in the rat. Pharmacology, Biochemistry, and Behavior. 38: 931-4. PMID 1651522  0.209
1994 Vandertop WP, de Vries WB, Notermans NC, Tulleken CA, Gispen WH. Experimentally-induced autonomic neuropathy: beneficial effect of a topical ACTH4-9 analogue on oculomotor nerve regeneration. Neurosurgery. 35: 457-61; discussion 4. PMID 7800137  0.209
1990 Müller LJ, Gerritsen van der Hoop R, Moorer-van Delft CM, Gispen WH, Roubos EW. Morphological and electrophysiological study of the effects of cisplatin and ORG.2766 on rat spinal ganglion neurons. Cancer Research. 50: 2437-42. PMID 2156619  0.209
1992 de Jong GI, Jansen AS, Horvath E, Gispen WH, Luiten PG. Nimodipine effects on cerebral microvessels and sciatic nerve in aging rats. Neurobiology of Aging. 13: 73-81. PMID 1542385  0.208
1995 Aarts LH, van der Linden JA, Hage WJ, van Rozen AJ, Oestreicher AB, Gispen WH, Schotman P. N-terminal cysteines essential for Golgi sorting of B-50 (GAP-43) in PC12 cells. Neuroreport. 6: 969-72. PMID 7632901  0.208
1986 Oestreicher AB, Dekker LV, Gispen WH. A radioimmunoassay for the phosphoprotein B-50: distribution in rat brain. Journal of Neurochemistry. 46: 1366-9. PMID 2937882 DOI: 10.1111/j.1471-4159.1986.tb01748.x  0.206
1991 Ramakers GJ, Oestreicher AB, Wolters PS, van Leeuwen FW, De Graan PN, Gispen WH. Developmental changes in B-50 (GAP-43) in primary cultures of cerebral cortex: B-50 immunolocalization, axonal elongation rate and growth cone morphology. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 9: 215-30. PMID 1833954 DOI: 10.1016/0736-5748(91)90042-K  0.205
1999 Dijkstra S, Bär PR, Gispen WH, Joosten EA. Selective stimulation of dendrite outgrowth from identified corticospinal neurons by homotopic astrocytes. Neuroscience. 92: 1331-42. PMID 10426488 DOI: 10.1016/S0306-4522(99)00060-3  0.204
1993 Florijn WJ, Mulder AH, Versteeg DH, Gispen WH. Adrenocorticotropin/alpha-melanocyte-stimulating hormone (ACTH/MSH)-like peptides modulate adenylate cyclase activity in rat brain slices: evidence for an ACTH/MSH receptor-coupled mechanism. Journal of Neurochemistry. 60: 2204-11. PMID 8388034  0.204
1994 Bäurle J, Oestreicher AB, Gispen WH, Grüsser-Cornehls U. Lesion-specific pattern of immunocytochemical distribution of growth-associated protein B-50 (GAP-43) in the cerebellum of Weaver and PCD-mutant mice: lack of B-50 involvement in neuroplasticity of Purkinje cell terminals? Journal of Neuroscience Research. 38: 327-35. PMID 7932867 DOI: 10.1002/jnr.490380311  0.204
1999 Aarts LH, Verkade P, van Dalen JJ, van Rozen AJ, Gispen WH, Schrama LH, Schotman P. B-50/GAP-43 potentiates cytoskeletal reorganization in raft domains. Molecular and Cellular Neurosciences. 14: 85-97. PMID 10532807 DOI: 10.1006/mcne.1999.0775  0.204
2000 Houben MP, Lankhorst AJ, van Dalen JJ, Veldman H, Joosten EA, Hamers FP, Gispen WH, Schrama LH. Pre- and postsynaptic localization of RC3/neurogranin in the adult rat spinal cord: an immunohistochemical study. Journal of Neuroscience Research. 59: 750-9. PMID 10700012 DOI: 10.1002/(SICI)1097-4547(20000315)59:6<750::AID-JNR7>3.0.CO;2-B  0.203
1991 Van der Neut R, Gispen WH, Bär PR. Serum from patients with amyotrophic lateral sclerosis induces the expression of B-50/GAP-43 and neurofilament in cultured rat fetal spinal neurons. Molecular and Chemical Neuropathology / Sponsored by the International Society For Neurochemistry and the World Federation of Neurology and Research Groups On Neurochemistry and Cerebrospinal Fluid. 14: 247-58. PMID 1835579  0.203
1995 Vandertop WP, de Vries WB, Notermans NC, Tulleken CA, Gispen WH. Neural influences on the iris of diabetic rats and effect of oculomotor nerve crush. Journal of the Autonomic Nervous System. 55: 112-4. PMID 8690843 DOI: 10.1016/0165-1838(95)00034-U  0.202
1991 van Lookeren Campagne M, Oestreicher AB, van der Krift TP, Gispen WH, Verkleij AJ. Freeze-substitution and Lowicryl HM20 embedding of fixed rat brain: suitability for immunogold ultrastructural localization of neural antigens. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 39: 1267-79. PMID 1833448  0.202
1986 Oestreicher AB, Gispen WH. Comparison of the immunocytochemical distribution of the phosphoprotein B-50 in the cerebellum and hippocampus of immature and adult rat brain. Brain Research. 375: 267-79. PMID 2942220 DOI: 10.1016/0006-8993(86)90747-X  0.2
1982 Kristjansson GI, Zwiers H, Oestreicher AB, Gispen WH. Evidence that the synaptic phosphoprotein B-50 is localized exclusively in nerve tissue. Journal of Neurochemistry. 39: 371-8. PMID 6211521 DOI: 10.1111/j.1471-4159.1982.tb03958.x  0.199
1998 Houweling DA, Lankhorst AJ, Gispen WH, Bär PR, Joosten EA. Collagen containing neurotrophin-3 (NT-3) attracts regrowing injured corticospinal axons in the adult rat spinal cord and promotes partial functional recovery. Experimental Neurology. 153: 49-59. PMID 9743566 DOI: 10.1006/exnr.1998.6867  0.199
1997 Di Luca M, Caputi A, Cattabeni F, De Graan PN, Gispen WH, Raiteri M, Fassio A, Schmid G, Bonanno G. Increased presynaptic protein kinase C activity and glutamate release in rats with a prenatally induced hippocampal lesion. The European Journal of Neuroscience. 9: 472-9. PMID 9104589 DOI: 10.1111/j.1460-9568.1997.tb01624.x  0.198
1993 De Graan PN, Moritz A, de Wit M, Gispen WH. Purification of B-50 by 2-mercaptoethanol extraction from rat brain synaptosomal plasma membranes. Neurochemical Research. 18: 875-81. PMID 8371830 DOI: 10.1007/BF00998271  0.197
1997 van Meeteren NL, Brakkee JH, Helders PJ, Wiegant VM, Gispen WH. Functional recovery from sciatic nerve crush lesion in the rat correlates with individual differences in responses to chronic intermittent stress. Journal of Neuroscience Research. 48: 524-32. PMID 9210522 DOI: 10.1002/(SICI)1097-4547(19970615)48:6<524::AID-JNR5>3.0.CO;2-C  0.196
1994 DeGraan PN, Hens JJ, Gispen WH. Presynaptic PKC substrate B-50 (GAP-43) and neurotransmitter release: studies with permeated synaptosomes. Neurotoxicology. 15: 41-7. PMID 7916446  0.196
1991 Ramakers GJ, De Graan PN, Oestreicher AB, Boer GJ, Corner MA, Gispen WH. Developmental changes in B-50 (GAP-43) in primary cultures of cerebral cortex: content and phosphorylation of B-50. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 9: 231-41. PMID 1833955 DOI: 10.1016/0736-5748(91)90043-L  0.194
1980 Zwiers H, Verhoef J, Schotman P, Gispen WH. A new phosphorylation-inhibiting peptide (PIP) with behavioral activity from rat brain membranes. Febs Letters. 112: 168-72. PMID 7189477 DOI: 10.1016/0014-5793(80)80172-4  0.194
1993 Schipper NG, Verhoef JC, De Lannoy LM, Romeijn SG, Brakkee JH, Wiegant VM, Gispen WH, Merkus FW. Nasal administration of an ACTH(4-9) peptide analogue with dimethyl-beta-cyclodextrin as an absorption enhancer: pharmacokinetics and dynamics. British Journal of Pharmacology. 110: 1335-40. PMID 8306072  0.194
1990 Hoop RGvd, Vecht C, Burg MVd, Elderson A, Boogerd W, Heimans J, Vries E, Houwelingen JV, Jennekens F, Gispen W, Neijt J. Citation from the literature OncologyPrevention of cisplatin neurotoxicity with an ACTH (4–9) analogue in patients with ovarian cancer International Journal of Gynecology & Obstetrics. 33. DOI: 10.1016/0020-7292(90)90051-L  0.194
1992 Van Lookeren Campagne M, Dotti CG, Jap Tjoen San ER, Verkleij AJ, Gispen WH, Oestreicher AB. B-50/GAP43 localization in polarized hippocampal neurons in vitro: an ultrastructural quantitative study. Neuroscience. 50: 35-52. PMID 1407559 DOI: 10.1016/0306-4522(92)90380-K  0.193
1994 Vandertop WP, de Vries WB, Notermans NC, Tulleken CA, Gispen WH. Experimentally induced autonomic neuropathy: beneficial effect of a systemic ACTH4-9 analogue on oculomotor nerve regeneration. Restorative Neurology and Neuroscience. 7: 37-43. PMID 21551770 DOI: 10.3233/RNN-1994-7106  0.192
1991 Mandys V, van der Neut R, Bär PR, Gispen WH. Cultivation of rat fetal spinal cord slices in a semi-solid medium: a new approach to studying axonal outgrowth and regeneration. Journal of Neuroscience Methods. 38: 63-9. PMID 1921469  0.192
1995 Van Dam PS, Van Asbeck BS, Erkelens DW, Marx JJ, Gispen WH, Bravenboer B. The role of oxidative stress in neuropathy and other diabetic complications. Diabetes/Metabolism Reviews. 11: 181-92. PMID 8536540 DOI: 10.1002/Dmr.5610110303  0.19
1991 Nielander HB, Van Rozen AJ, Schrama LH, Kasparaitis M, Oestreicher AB, Gispen WH, Schotman P. Phosphoprotein B-50: localization of proteolytic sites for S. aureus V8 protease using truncated cRNAs for cell-free translation. Journal of Molecular Neuroscience : Mn. 3: 85-93. PMID 1726045  0.19
1989 Terheggen PM, van der Hoop RG, Floot BG, Gispen WH. Cellular distribution of cis-diamminedichloroplatinum(II)-DNA binding in rat dorsal root spinal ganglia: effect of the neuroprotecting peptide ORG.2766. Toxicology and Applied Pharmacology. 99: 334-43. PMID 2544043 DOI: 10.1016/0041-008X(89)90015-X  0.19
1998 van Meeteren NL, Brakkee JH, Helders PJ, Gispen WH. The effect of exercise training on functional recovery after sciatic nerve crush in the rat. Journal of the Peripheral Nervous System : Jpns. 3: 277-82. PMID 10970128  0.189
1988 Oestreicher AB, Devay P, Isaacson RL, Gispen WH. Changes in the distribution of the neuron-specific B-50, neurofilament protein and glial fibrillary acidic proteins following an unilateral mesencephalic lesion in the rat. Brain Research Bulletin. 21: 713-22. PMID 3146409 DOI: 10.1016/0361-9230(88)90037-8  0.189
1991 Edwards PM, Sporel-Ozakat RE, Gispen WH. Peripheral pain fiber function is relatively insensitive to the neurotoxic actions of acrylamide in the rat. Toxicology and Applied Pharmacology. 111: 43-8. PMID 1658984  0.189
1989 Van Lookeren Campagne M, Oestreicher A, van Bergen en Henegouwen P, Gispen W. Localization of B-50/GAP43 and synaptophysin in the neonatal and adult rat brain Cell Differentiation and Development. 27: 197. DOI: 10.1016/0922-3371(89)90598-4  0.188
1983 Aloyo VJ, Spruijt B, Zwiers H, Gispen WH. Peptide-induced excessive grooming in the rat: The role of opiate receptors Peptides. 4: 833-836. PMID 6324139 DOI: 10.1016/0196-9781(83)90076-1  0.188
1990 Van der Zee CE, Schuurman T, van der Hoop RG, Traber J, Gispen WH. Beneficial effect of nimodipine on peripheral nerve function in aged rats. Neurobiology of Aging. 11: 451-6. PMID 2381504  0.188
1997 van de Meent H, Hamers FP, Lankhorst AJ, Joosten EA, Gispen WH. Beneficial effects of the melanocortin alpha-melanocyte-stimulating hormone on clinical and neurophysiological recovery after experimental spinal cord injury. Neurosurgery. 40: 122-30; discussion 1. PMID 8971834 DOI: 10.1097/00006123-199701000-00028  0.187
2001 Biessels GJ, Smale S, Duis SE, Kamal A, Gispen WH. The effect of gamma-linolenic acid-alpha-lipoic acid on functional deficits in the peripheral and central nervous system of streptozotocin-diabetic rats. Journal of the Neurological Sciences. 182: 99-106. PMID 11137514 DOI: 10.1016/S0022-510X(00)00456-1  0.187
1992 Hendriksen PH, Oey PL, Wieneke GH, van Huffelen AC, Gispen WH. Hypoxic neuropathy versus diabetic neuropathy. An electrophysiological study in rats. Journal of the Neurological Sciences. 110: 99-106. PMID 1506876  0.186
2004 Nijenhuis WA, Wanders N, Kruijtzer JA, Liskamp RM, Gispen WH, Adan RA. Accelerating sensory recovery after sciatic nerve crush: non-selective versus melanocortin MC4 receptor-selective peptides. European Journal of Pharmacology. 495: 145-52. PMID 15249163 DOI: 10.1016/j.ejphar.2004.05.037  0.186
1990 Dekker LV, De Graan PN, Spierenburg H, De Wit M, Versteeg DH, Gispen WH. Evidence for a relationship between B-50 (GAP-43) and [3H]noradrenaline release in rat brain synaptosomes. European Journal of Pharmacology. 188: 113-22. PMID 1969352 DOI: 10.1016/0922-4106(90)90046-Z  0.186
1997 Edgar MA, Pasinelli P, DeWit M, Anton B, Dokas LA, Pastorino L, DiLuca M, Cattabeni F, Gispen WH, De Graan PN. Phosphorylation of the casein kinase II domain of B-50 (GAP-43) in rat cortical growth cones. Journal of Neurochemistry. 69: 2206-15. PMID 9349568 DOI: 10.1046/J.1471-4159.1997.69052206.X  0.185
1995 Eggen BJ, Brandsma D, Kasperaitis M, Gispen WH, Schrama LH. Rat B-50 gene transcription and translation. Brain Research. 690: 73-81. PMID 7496809 DOI: 10.1016/0006-8993(95)00589-I  0.185
1989 Van Hooff C, De Graan P, Oestreicher A, Gispen W. Muscarinic receptor activation stimulates B-50/GAP43 phosphorylation in isolated nerve growth cones The Journal of Neuroscience. 9: 3753-3759. DOI: 10.1523/JNEUROSCI.09-11-03753.1989  0.183
1992 GISPEN WH. EFFECTS OF ACTH NEUROPEPTIDES ON NERVE REPAIR AND NEUROPATHY, ANIMAL AND HUMAN STUDIES Behavioural Pharmacology. 3: 11. DOI: 10.1097/00008877-199204001-00028  0.183
1977 Wiegant VM, Gispen WH. ACTH-induced excessive grooming in the rat: latent activity of ACTH4-10. Behavioral Biology. 19: 554-8. PMID 193484 DOI: 10.1016/S0091-6773(77)92083-1  0.183
1981 Gispen WH, Isaacson RL. ACTH-induced excessive grooming in the rat. Pharmacology & Therapeutics. 12: 209-46. PMID 6114501 DOI: 10.1016/0163-7258(81)90081-4  0.183
1996 Van Rijzingen IM, Van Doremalen E, Josephy M, Gispen WH, Spruijt BM. ACTH(4-9) analog ORG2766 treatment 7 months delayed still improves morris maze performance of fimbria-lesioned rats. Pharmacology, Biochemistry, and Behavior. 53: 163-9. PMID 8848446 DOI: 10.1016/0091-3057(95)02011-X  0.183
1993 van Meeteren NLU, Brakkee JH, Gispen WH. The effect of physical exercise on functional recovery following a peripheral nerve lesion in the rat Physiotherapy Theory and Practice. 9: 77-85. DOI: 10.3109/09593989309052919  0.183
2005 Biessels GJ, ter Laak MP, Kamal A, Gispen WH. Effects of the Ca2+ antagonist nimodipine on functional deficits in the peripheral and central nervous system of streptozotocin-diabetic rats. Brain Research. 1035: 86-93. PMID 15713280 DOI: 10.1016/j.brainres.2004.12.025  0.182
1991 Jap Tjoen San ER, Schmidt-Michels MH, Spruijt BM, Oestreicher AB, Schotman P, Gispen WH. Quantitation of the growth-associated protein B-50/GAP-43 and neurite outgrowth in PC12 cells. Journal of Neuroscience Research. 29: 149-54. PMID 1832465 DOI: 10.1002/jnr.490290203  0.182
1990 Jap Tjoen San E, Schmidt-Michels M, Oestreicher B, Schotman P, Gispen W. Dexamethasone inhibits B-50 (GAP-43) protein expression and neurite formation in PCS2 cells European Journal of Pharmacology. 183: 1686-1687. DOI: 10.1016/0014-2999(90)91981-G  0.182
1996 Biessels G, Kappelle AC, Van Buren T, Bravenboer B, Gispen WH. Effects of the combination of Org 2766 and nimodipine on nerve conduction velocity in streptozotocin-diabetic rats Diabetes, Nutrition and Metabolism - Clinical and Experimental. 9: 29-32.  0.181
1993 Di Luca M, Merazzi F, De Graan PN, Cimino M, Balduini W, Gispen WH, Cattabeni F. Selective alteration in B-50/GAP-43 phosphorylation in brain areas of animals characterized by cognitive impairment. Brain Research. 607: 329-32. PMID 8481807 DOI: 10.1016/0006-8993(93)91525-W  0.18
1995 Joosten EA, Bär PR, Gispen WH. Directional regrowth of lesioned corticospinal tract axons in adult rat spinal cord. Neuroscience. 69: 619-26. PMID 8552254 DOI: 10.1016/0306-4522(95)00270-S  0.18
1986 Spruijt BM, Ellenbroek B, Cools AR, Gispen WH. The colliculus superior modulates ACTH-induced excessive grooming. Life Sciences. 39: 461-70. PMID 3016441 DOI: 10.1016/0024-3205(86)90526-6  0.18
1995 van Rijzingen IM, Gispen WH, Spruijt BM. Olfactory bulbectomy temporarily impairs Morris maze performance: an ACTH(4-9) analog accellerates return of function. Physiology & Behavior. 58: 147-52. PMID 7667412 DOI: 10.1016/0031-9384(95)00032-E  0.177
1989 Jap Tjoen San E, Schmidt-Michels M, Oestreicher A, Spruijt B, Schotman P, Gispen W. Quantitative analysis of NGF induced neurite formation in PC12 cells: The role of protein kinase C and its neuron specific substrate B-50 Cell Differentiation and Development. 27: 195. DOI: 10.1016/0922-3371(89)90591-1  0.176
1996 Joosten EA, Reshilov LN, Gispen WH, Bär PR. Embryonic form of N-CAM and development of the rat corticospinal tract; immuno-electron microscopical localization during spinal white matter ingrowth. Brain Research. Developmental Brain Research. 94: 99-105. PMID 8816282 DOI: 10.1016/0165-3806(96)00017-X  0.176
1996 Van Buren T, Kasbergen CM, Gispen WH, De Wildt DJ. Presynaptic deficit of sympathetic nerves: a cause for disturbed sciatic nerve blood flow responsiveness in diabetic rats. European Journal of Pharmacology. 296: 277-83. PMID 8904079 DOI: 10.1016/0014-2999(95)00718-0  0.176
1993 Bravenboer B, Kappelle AC, van Buren T, Erkelens DW, Gispen WH. ACTH4-9 analogue ORG 2766 can improve existing neuropathy in streptozocin-induced diabetic rats. Acta Diabetologica. 30: 21-4. PMID 8392402 DOI: 10.1007/BF00572869  0.175
1995 Jap Tjoen San ER, van Rozen AJ, Nielander HB, Oestreicher AB, Gispen WH, Schotman P. Expression levels of B-50/GAP-43 in PC12 cells are decisive for the complexity of their neurites and growth cones. Journal of Molecular Neuroscience : Mn. 6: 185-200. PMID 8672401 DOI: 10.1007/BF02736764  0.175
1994 Kappelle AC, Biessels G, Bravenboer B, van Buren T, Traber J, de Wildt DJ, Gispen WH. Beneficial effect of the Ca2+ antagonist, nimodipine, on existing diabetic neuropathy in the BB/Wor rat. British Journal of Pharmacology. 111: 887-93. PMID 8019766 DOI: 10.1111/j.1476-5381.1994.tb14821.x  0.174
1995 Cízková D, Sekerková G, Oestreicher AB, Gispen WH, Zigová T. Distribution of growth associated protein (B-50/GAP-43) and glial fibrillary acidic protein (GFAP) immunoreactivity in rat homotopic olfactory bulb transplants. Archives Italiennes De Biologie. 133: 237-50. PMID 8849315  0.174
1992 Bravenboer B, Kappelle AC, Hamers FP, van Buren T, Erkelens DW, Gispen WH. Potential use of glutathione for the prevention and treatment of diabetic neuropathy in the streptozotocin-induced diabetic rat. Diabetologia. 35: 813-7. PMID 1397775 DOI: 10.1007/BF00399926  0.173
1999 van Dam PS, Bravenboer B, van Asbeck BS, Marx JJ, Gispen WH. High rat food vitamin E content improves nerve function in streptozotocin-diabetic rats. European Journal of Pharmacology. 376: 217-22. PMID 10448879 DOI: 10.1016/S0014-2999(99)00376-3  0.172
1995 Vandertop WP, de Vries WB, Notermans NC, Tulleken CA, Gispen WH. Beneficial effect of an ACTH4-9 analogue on experimentally induced diabetic autonomic neuropathy in the eye of the rat under general anaesthesia. Journal of the Autonomic Nervous System. 51: 49-57. PMID 7722215 DOI: 10.1016/0165-1838(95)80006-V  0.171
2000 Lankhorst AJ, ter Laak MP, Hamers FP, Gispen WH. Combined treatment with alphaMSH and methylprednisolone fails to improve functional recovery after spinal injury in the rat. Brain Research. 859: 334-40. PMID 10719082 DOI: 10.1016/S0006-8993(00)02025-4  0.171
1988 Van Hooff C, De Graan P, Oestreicher A, Gispen W. B-50 phosphorylation and polyphosphoinositide metabolism in nerve growth cone membranes The Journal of Neuroscience. 8: 1789-1795. DOI: 10.1523/JNEUROSCI.08-05-01789.1988  0.171
1983 Isaacson RL, Hannigan JH, Brakkee JH, Gispen WH. The time course of excessive grooming after neuropeptide administration. Brain Research Bulletin. 11: 289-93. PMID 6315189 DOI: 10.1016/0361-9230(83)90162-4  0.17
1995 Hens JJ, De Wit M, Boomsma F, Mercken M, Oestreicher AB, Gispen WH, De Graan PN. N-terminal-specific anti-B-50 (GAP-43) antibodies inhibit Ca(2+)-induced noradrenaline release, B-50 phosphorylation and dephosphorylation, and calmodulin binding. Journal of Neurochemistry. 64: 1127-36. PMID 7861143 DOI: 10.1046/j.1471-4159.1995.64031127.x  0.169
1992 Van Lookeren Campagne M, Dotti CG, Verkleij AJ, Gispen WH, Oestreicher AB. B-50/GAP43 localization on membranes of putative transport vesicles in the cell body, neurites and growth cones of cultured hippocampal neurons. Neuroscience Letters. 137: 129-32. PMID 1385647 DOI: 10.1016/0304-3940(92)90314-W  0.168
1995 Di Luca M, Caputi A, Cinquanta M, Cimino M, Marini P, Princivalle A, De Graan PN, Gispen WH, Cattabeni F. Changes in protein kinase C and its presynaptic substrate B-50/GAP-43 after intrauterine exposure to methylazoxy-methanol, a treatment inducing cortical and hippocampal damage and cognitive deficit in rats. The European Journal of Neuroscience. 7: 899-906. PMID 7613626 DOI: 10.1111/j.1460-9568.1995.tb01077.x  0.168
1988 Aloyo VJ, Zwiers H, De Graan PN, Gispen WH. Phosphorylation of the neuronal protein kinase C substrate B-50: in vitro assay conditions alter sensitivity to ACTH. Neurochemical Research. 13: 343-8. PMID 3393264 DOI: 10.1007/Bf00972484  0.168
1993 Nielander HB, French P, Oestreicher AB, Gispen WH, Schotman P. Spontaneous morphological changes by overexpression of the growth-associated protein B-50/GAP-43 in a PC12 cell line. Neuroscience Letters. 162: 46-50. PMID 8121634 DOI: 10.1016/0304-3940(93)90556-Z  0.168
1999 Van Dam PS, Van Asbeck BS, Bravenboer B, Van Oirschot JF, Marx JJ, Gispen WH. Nerve conduction and antioxidant levels in experimentally diabetic rats: effects of streptozotocin dose and diabetes duration. Metabolism: Clinical and Experimental. 48: 442-7. PMID 10206435  0.168
1999 Aarts LH, Verkade P, Schrama LH, Oestreicher AB, Gispen WH, Schotman P. Local accumulations of B-50/GAP-43 evoke excessive bleb formation in PC12 cells. Molecular Neurobiology. 20: 17-28. PMID 10595870 DOI: 10.1007/BF02741362  0.168
1994 Hamers FP, Klis SF, Gispen WH, Smoorenburg GF. Application of a neuroprotective ACTH(4-9) analog to affect cisplatin ototoxicity: an electrocochleographic study in guinea pigs. European Archives of Oto-Rhino-Laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (Eufos) : Affiliated With the German Society For Oto-Rhino-Laryngology - Head and Neck Surgery. 251: 23-9. PMID 8179863  0.167
2000 Vrinten DH, Gispen WH, Groen GJ, Adan RA. Antagonism of the melanocortin system reduces cold and mechanical allodynia in mononeuropathic rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 8131-7. PMID 11050135  0.167
1974 Gispen W, de Kloet E, Reith M, Wiegant V, Schotman P. Pituitary, peptides and brain function: some neurochemical aspects Brain Research. 66: 368-369. DOI: 10.1016/0006-8993(74)90182-6  0.166
1991 Danks AM, Oestreicher AB, Spruijt BM, Gispen WH, Isaacson RL. Behavioral and anatomical consequences of unilateral fornix lesions and the administration of nimodipine. Brain Research. 557: 308-12. PMID 1747762 DOI: 10.1016/0006-8993(91)90150-T  0.166
2003 Vogelaar CF, Smits SM, Brakkee JH, Gispen WH, Smidt MP, Schrama LH, Hoekman MFM, Burbach JPH. Homeobox gene repertoire in adult rat dorsal root ganglia Neuroscience Research Communications. 32: 49-59. DOI: 10.1002/nrc.10058  0.166
1997 Verhage M, de Vries KJ, Røshol H, Burbach JP, Gispen WH, Südhof TC. DOC2 proteins in rat brain: complementary distribution and proposed function as vesicular adapter proteins in early stages of secretion. Neuron. 18: 453-61. PMID 9115738 DOI: 10.1016/S0896-6273(00)81245-3  0.165
1996 Di Luca M, Pastorino L, Raverdino V, De Graan PN, Caputi A, Gispen WH, Cattabeni F. Determination of the endogenous phosphorylation state of B-50/GAP-43 and neurogranin in different brain regions by electrospray mass spectrometry. Febs Letters. 389: 309-13. PMID 8766722 DOI: 10.1016/0014-5793(96)00612-6  0.164
1986 De Graan PN, Spruijt BM, Eberle AN, Girard J, Gispen WH. ACTH1-4 potentiates alpha-MSH-induced melanophore dispersion and excessive grooming. Peptides. 7: 1-4. PMID 3012487 DOI: 10.1016/0196-9781(86)90051-3  0.164
1992 Mandys V, Gispen W, Bär P. αMSH improves axonal outgrowth from dorsal root ganglia treated in vitro with cisplatin Neurochemistry International. 21: A3. DOI: 10.1016/0197-0186(92)91907-E  0.164
1981 Schotman P, Allaart J, Gispen WH. Pineal protein synthesis highly sensitive to ACTH-like neuropeptides. Brain Research. 219: 121-35. PMID 6266596 DOI: 10.1016/0006-8993(81)90272-9  0.163
1979 Zwiers H, Tonnaer J, Wiegant VM, Schotman P, Gispen WH. ACTH-sensitive protein kinase from rat brain membranes. Journal of Neurochemistry. 33: 247-56. PMID 222880 DOI: 10.1111/j.1471-4159.1979.tb11726.x  0.163
1993 Kappelle AC, Bravenboer B, van Buren T, Traber J, Erkelens DW, Gispen WH. Amelioration by the Ca2+ antagonist, nimodipine of an existing neuropathy in the streptozotocin-induced, diabetic rat. British Journal of Pharmacology. 108: 780-5. PMID 8467365 DOI: 10.1111/j.1476-5381.1993.tb12878.x  0.163
1990 Nielander HB, Schrama LH, van Rozen AJ, Kasperaitis M, Oestreicher AB, Gispen WH, Schotman P. Mutation of serine 41 in the neuron-specific protein B-50 (GAP-43) prohibits phosphorylation by protein kinase C. Journal of Neurochemistry. 55: 1442-5. PMID 2144585  0.163
1994 Eggen BJ, Nielander HB, Rensen-de Leeuw MG, Schotman P, Gispen WH, Schrama LH. Identification of two promoter regions in the rat B-50/GAP-43 gene. Brain Research. Molecular Brain Research. 23: 221-34. PMID 8057779 DOI: 10.1016/0169-328X(94)90229-1  0.162
1986 Schrama LH, De Graan PN, Eichberg J, Gispen WH. Feedback control of the inositol phospholipid response in rat brain is sensitive to ACTH. European Journal of Pharmacology. 121: 403-4. PMID 3009210 DOI: 10.1016/0014-2999(86)90261-X  0.162
1983 Dokas LA, Zwiers H, Coy DH, Gispen WH. Somatostatin and analogs inhibit endogenous synaptic plasma membrane protein phosphorylation in vitro. European Journal of Pharmacology. 88: 185-93. PMID 6133768 DOI: 10.1016/0014-2999(83)90005-5  0.162
1985 Van Dongen CJ, Zwiers H, De Graan PN, Gispen WH. Modulation of the activity of purified phosphatidylinositol 4-phosphate kinase by phosphorylated and dephosphorylated B-50 protein. Biochemical and Biophysical Research Communications. 128: 1219-27. PMID 2988532 DOI: 10.1016/0006-291X(85)91070-8  0.162
1994 Adan RA, Oosterom J, Ludvigsdottir G, Brakkee JH, Burbach JP, Gispen WH. Identification of antagonists for melanocortin MC3, MC4 and MC5 receptors. European Journal of Pharmacology. 269: 331-7. PMID 7895772 DOI: 10.1016/0922-4106(94)90041-8  0.161
1990 Heemskerk FM, Schrama LH, Gianotti C, Spierenburg H, Versteeg DH, De Graan PN, Gispen WH. 4-Aminopyridine stimulates B-50 (GAP43) phosphorylation and [3H]noradrenaline release in rat hippocampal slices. Journal of Neurochemistry. 54: 863-9. PMID 2137530 DOI: 10.1111/j.1471-4159.1990.tb02331.x  0.16
1990 Heemskerk FM, Schrama LH, De Graan PN, Gispen WH. 4-Aminopyridine stimulates B-50 (GAP-43) phosphorylation in rat synaptosomes. Journal of Molecular Neuroscience : Mn. 2: 11-7. PMID 2147857 DOI: 10.1007/BF02896921  0.16
1994 Joosten EA, Gispen WH, Bär PR. Tropism and corticospinal target selection in the rat. Neuroscience. 59: 33-41. PMID 8190270 DOI: 10.1016/0306-4522(94)90096-5  0.16
1980 Zwiers H, Schotman P, Gispen WH. Purification and some characteristics of an ACTH-sensitive protein kinase and its substrate protein in rat brain membranes. Journal of Neurochemistry. 34: 1689-99. PMID 6247451 DOI: 10.1111/J.1471-4159.1980.TB11262.X  0.16
1977 Gispen WH, Schotman P. ACTH and brain RNA: changes in content and labelling of RNA in rat brain stem. Neuroendocrinology. 21: 97-110. PMID 189247 DOI: 10.1159/000122516  0.159
1982 Traber J, Klein HR, Gispen WH. Actions of antidepressant and neuroleptic drugs on ACTH- and novelty-induced behavior in the rat. European Journal of Pharmacology. 80: 407-14. PMID 6125402 DOI: 10.1016/0014-2999(82)90087-5  0.159
1990 Gispen WH. Therapeutic potential for melanocortins in peripheral nerve disease. Trends in Pharmacological Sciences. 11: 221-2. PMID 2166368  0.159
1982 Aloyo VJ, Zwiers H, Gispen WH. B-50 Protein Kinase and Kinase C in Rat Brain Progress in Brain Research. 56: 303-315. PMID 6219430 DOI: 10.1016/S0079-6123(08)63781-4  0.159
1986 Spruijt BM, Cools AR, Ellenbroek BA, Gispen WH. Dopaminergic modulation of ACTH-induced grooming. European Journal of Pharmacology. 120: 249-56. PMID 3005003 DOI: 10.1016/0014-2999(86)90465-6  0.158
1983 Tielen AM, de Graan PN, Mollevanger WJ, Lopes da Silva FH, Gispen WH. Quantitative relationship between post-tetanic biochemical and electrophysiological changes in rat hippocampal slices. Brain Research. 277: 189-92. PMID 6315139  0.158
1978 Cools AR, Wiegant VM, Gispen WH. Distinct dopaminergic systems in ACTH-induced grooming. European Journal of Pharmacology. 50: 265-8. PMID 211042 DOI: 10.1016/0014-2999(78)90359-X  0.158
1995 Joosten EA, Bär PR, Gispen WH. Collagen implants and cortico-spinal axonal growth after mid-thoracic spinal cord lesion in the adult rat. Journal of Neuroscience Research. 41: 481-90. PMID 7473879 DOI: 10.1002/jnr.490410407  0.158
1998 Dokas LA, Ting S, Edgar MA, Oestreicher AB, Gispen WH, DeGraan PN. Regulation of in vitro phosphorylation of the casein kinase II sites in B-50 (GAP-43). Brain Research. 781: 320-8. PMID 9507176 DOI: 10.1016/S0006-8993(97)01257-2  0.157
2004 Manschot SM, Kappelle LJ, Gispen WH, Biessels GJ. Long-term angiotensin converting enzyme inhibition dose-dependently improves nerve conduction velocity and evoked potential latencies in streptozotocin-diabetic rats Neuroscience Research Communications. 35: 51-62. DOI: 10.1002/nrc.20019  0.157
1987 Schrama LH, De Graan PN, Oestreicher AB, Gispen WH. B-50 phosphorylation, protein kinase C and the induction of excessive grooming behavior in the rat. Advances in Experimental Medicine and Biology. 221: 393-408. PMID 2829585 DOI: 10.1007/978-1-4684-7618-7_29  0.157
1998 van Dam PS, van Asbeck BS, Bravenboer B, van Oirschot JF, Gispen WH, Marx JJ. Nerve function and oxidative stress in diabetic and vitamin E-deficient rats. Free Radical Biology & Medicine. 24: 18-26. PMID 9436610 DOI: 10.1016/S0891-5849(97)00122-6  0.156
1992 Di Luca M, de Graan PN, De Angelis L, Gispen WH, Cattabeni F. Measurement of relative amounts of phospho- and dephospho-B-50(GAP-43) peptides by fast atom bombardment-mass spectrometry. Febs Letters. 301: 150-4. PMID 1533190  0.155
1998 van der Kraan M, Adan RA, Entwistle ML, Gispen WH, Burbach JP, Tatro JB. Expression of melanocortin-5 receptor in secretory epithelia supports a functional role in exocrine and endocrine glands. Endocrinology. 139: 2348-55. PMID 9564844 DOI: 10.1210/endo.139.5.6008  0.155
1993 Joosten EA, Bär PR, Gispen WH, Bregman BS. Transient projections from rat occipital cortex are able to respond to a spinal target derived diffusible factor in vitro. Neuroscience Letters. 164: 85-8. PMID 8152621 DOI: 10.1016/0304-3940(93)90863-G  0.155
1991 Dekker LV, De Graan PN, Pijnappel P, Oestreicher AB, Gispen WH. Noradrenaline release from streptolysin O-permeated rat cortical synaptosomes: effects of calcium, phorbol esters, protein kinase inhibitors, and antibodies to the neuron-specific protein kinase C substrate B-50 (GAP-43). Journal of Neurochemistry. 56: 1146-53. PMID 1825843  0.155
1989 Gorgels T, Van Lookeren Campagne M, Oestreicher A, Gribnau A, Gispen W. B-50/GAP43 is localized at the cytoplasmic side of the plasma membrane in developing and adult rat pyramidal tract The Journal of Neuroscience. 9: 3861-3869. DOI: 10.1523/JNEUROSCI.09-11-03861.1989  0.154
2000 Proper EA, Oestreicher AB, Jansen GH, Veelen CW, van Rijen PC, Gispen WH, de Graan PN. Immunohistochemical characterization of mossy fibre sprouting in the hippocampus of patients with pharmaco-resistant temporal lobe epilepsy. Brain : a Journal of Neurology. 123: 19-30. PMID 10611117  0.154
1999 Hoogland G, Blomenröhr M, Dijstelbloem H, de Wit M, Spierenburg HA, van Veelen CW, van Rijen PC, van Huffelen AC, Gispen WH, de Graan PN. Characterization of neocortical and hippocampal synaptosomes from temporal lobe epilepsy patients. Brain Research. 837: 55-66. PMID 10433988 DOI: 10.1016/S0921-4534(99)00331-7  0.154
1990 van Lookeren Campagne M, Oestreicher A, van der Krift T, Gispen W, Verkleij A. Immunogold ultrastructural localization of neural antigens in Lowicryl HM20 embedded, freeze substituted rat brain tissue Micron and Microscopica Acta. 21: 225-226. DOI: 10.1016/0739-6260(90)90123-W  0.153
1982 Aloyo VJ, Zwiers H, Gispen WH. ACTH1–24 Releases a Protein from Synaptosomal Plasma Membranes Journal of Neurochemistry. 38: 871-875. PMID 6278086 DOI: 10.1111/j.1471-4159.1982.tb05323.x  0.153
1993 Kappelle AC, Biessels GJ, Van Buren T, Erkelens DW, De Wildt DJ, Gispen WH. Effects of nimodipine on sciatic nerve blood flow and vasa nervorum responsiveness in the diabetic rat. European Journal of Pharmacology. 250: 43-9. PMID 8119324 DOI: 10.1016/0014-2999(93)90619-S  0.153
1971 Gispen WH, Schotman P. Effect of hypophysectomy and conditioned avoidance behavior on macromolecule metabolism in the brain stem of the rat. Progress in Brain Research. 32: 236-44. PMID 5491103 DOI: 10.1016/S0079-6123(08)61539-3  0.152
1977 Colbern D, Isaacson RL, Bohus B, Gispen WH. Limbic-midbrain lesions and ACTH-induced excessive grooming. Life Sciences. 21: 393-401. PMID 197362 DOI: 10.1016/0024-3205(77)90520-3  0.152
1992 Gianotti C, Nunzi MG, Gispen WH, Corradetti R. Phosphorylation of the presynaptic protein B-50 (GAP-43) is increased during electrically induced long-term potentiation. Neuron. 8: 843-8. PMID 1534012 DOI: 10.1016/0896-6273(92)90198-M  0.152
2005 Kruijtzer JA, Nijenhuis WA, Wanders N, Gispen WH, Liskamp RM, Adan RA. Peptoid-peptide hybrids as potent novel melanocortin receptor ligands. Journal of Medicinal Chemistry. 48: 4224-30. PMID 15974575 DOI: 10.1021/Jm0490033  0.152
1999 Adan RA, Szklarczyk AW, Oosterom J, Brakkee JH, Nijenhuis WA, Schaaper WM, Meloen RH, Gispen WH. Characterization of melanocortin receptor ligands on cloned brain melanocortin receptors and on grooming behavior in the rat. European Journal of Pharmacology. 378: 249-58. PMID 10493100 DOI: 10.1016/S0014-2999(99)00465-3  0.152
1981 Bär PR, Gispen WH, Isaacson RL. Behavioral and regional neurochemical sequelae of hippocampal destruction in the rat. Pharmacology, Biochemistry, and Behavior. 14: 305-12. PMID 6262839 DOI: 10.1016/0091-3057(81)90395-6  0.152
1996 Adan RA, van der Kraan M, Doornbos RP, Bär PR, Burbach JP, Gispen WH. Melanocortin receptors mediate alpha-MSH-induced stimulation of neurite outgrowth in neuro 2A cells. Brain Research. Molecular Brain Research. 36: 37-44. PMID 9011763 DOI: 10.1016/0169-328X(95)00236-L  0.151
1997 van Rijzingen IM, Gispen WH, Spruijt BM. Postoperative environmental enrichment attenuates fimbria-fornix lesion-induced impairments in Morris maze performance. Neurobiology of Learning and Memory. 67: 21-8. PMID 9013497 DOI: 10.1006/nlme.1996.3735  0.151
1990 Schotman P, Nielander HB, Van Rozen AJ, Frankena H, Schrama LH, Gispen WH. Microheterogeneity of the growth-associated neuronal protein B-50 (GAP-43). Contribution of phosphorylation by protein kinase Ca. Journal of Chromatography. 483: 301-9. PMID 2625438 DOI: 10.1016/S0021-9673(01)93129-2  0.151
2001 Vrinten DH, Adan RA, Groen GJ, Gispen WH. Chronic blockade of melanocortin receptors alleviates allodynia in rats with neuropathic pain. Anesthesia and Analgesia. 93: 1572-7, table of con. PMID 11726447  0.151
1988 Traber J, Spencer DG, Glaser T, Gispen WH. Actions of psychoactive drugs on ACTH- and novelty-induced behavior in the rat. Annals of the New York Academy of Sciences. 525: 270-80. PMID 2839068 DOI: 10.1111/j.1749-6632.1988.tb38612.x  0.15
1998 Von Frijtag JC, Croiset G, Gispen WH, Adan RA, Wiegant VM. The role of central melanocortin receptors in the activation of the hypothalamus-pituitary-adrenal-axis and the induction of excessive grooming. British Journal of Pharmacology. 123: 1503-8. PMID 9605554 DOI: 10.1038/sj.bjp.0701750  0.149
1990 Dekker LV, De Graan PN, De Wit M, Hens JJ, Gispen WH. Depolarization-induced phosphorylation of the protein kinase C substrate B-50 (GAP-43) in rat cortical synaptosomes. Journal of Neurochemistry. 54: 1645-52. PMID 2139108 DOI: 10.1111/j.1471-4159.1990.tb01217.x  0.149
1981 Van Dijk AMA, King GB, Schotman P, Gispen WH. GTP-sensitive phosphorylation of proteins in a postmitochondrial supernatant from rat brainstem affected by ACTH1-24 Neurochemical Research. 6: 847-861. PMID 6273759 DOI: 10.1007/BF00965043  0.149
1990 Heemskerk FM, Schrama LH, Gispen WH. Activation of protein kinase C by 4-aminopyridine dependent on Na+ channel activity in rat hippocampal slices. Neuroscience Letters. 106: 315-21. PMID 2557567 DOI: 10.1016/0304-3940(89)90183-3  0.149
1980 Bär PR, Schotman P, Gispen WH. Enkephalins affect hippocampal membrane phosphorylation. European Journal of Pharmacology. 65: 165-74. PMID 7398785 DOI: 10.1016/0014-2999(80)90389-1  0.148
1995 de Groen PC, Eggen BJ, Gispen WH, Schotman P, Schrama LH. Cloning and promoter analysis of the human B-50/GAP-43 gene. Journal of Molecular Neuroscience : Mn. 6: 109-19. PMID 8746449 DOI: 10.1007/BF02736770  0.147
1993 Nielander HB, De Groen PC, Eggen BJ, Schrama LH, Gispen WH, Schotman P. Structure of the human gene for the neural phosphoprotein B-50 (GAP-43). Brain Research. Molecular Brain Research. 19: 293-302. PMID 8231732 DOI: 10.1016/0169-328X(93)90128-C  0.147
1988 Gispen WH. Transmembrane signal transduction and ACTH-induced excessive grooming in the rat. Annals of the New York Academy of Sciences. 525: 141-9. PMID 2839063 DOI: 10.1111/j.1749-6632.1988.tb38602.x  0.147
1993 Ramakers GM, Urban IJ, De Graan PN, Di Luca M, Cattabeni F, Gispen WH. The impaired long-term potentiation in the CA1 field of the hippocampus of cognitive deficient microencephalic rats is restored by D-serine. Neuroscience. 54: 49-60. PMID 8100048 DOI: 10.1016/0306-4522(93)90382-P  0.147
2000 Adan RA, Gispen WH. Melanocortins and the brain: from effects via receptors to drug targets. European Journal of Pharmacology. 405: 13-24. PMID 11033310 DOI: 10.1016/S0014-2999(00)00537-9  0.146
2006 Koopmans GC, Brans M, Gómez-Pinilla F, Duis S, Gispen WH, Torres-Aleman I, Joosten EA, Hamers FP. Circulating insulin-like growth factor I and functional recovery from spinal cord injury under enriched housing conditions. The European Journal of Neuroscience. 23: 1035-46. PMID 16519668 DOI: 10.1111/J.1460-9568.2006.04627.X  0.145
1988 De Graan PN, Dekker LV, De Wit M, Schrama LH, Gispen WH. Modulation of B-50 phosphorylation and polyphosphoinositide metabolism in synaptic plasma membranes by protein kinase C, phorbol diesters and ACTH. Journal of Receptor Research. 8: 345-61. PMID 2838621 DOI: 10.3109/10799898809048997  0.145
1987 Heemskerk FM, Schrama LH, de Graan PN, Gispen WH. 4-Aminopyridine inhibits synaptosomal plasma membrane protein phosphorylation in vitro: effect of the selective NMDA-antagonist 2-amino-5-phosphonovalerate. Biochemical and Biophysical Research Communications. 147: 94-9. PMID 2443136 DOI: 10.1016/S0006-291X(87)80091-8  0.144
1997 van Meeteren NL, Brakkee JH, Hamers FP, Helders PJ, Gispen WH. Exercise training improves functional recovery and motor nerve conduction velocity after sciatic nerve crush lesion in the rat. Archives of Physical Medicine and Rehabilitation. 78: 70-7. PMID 9014961 DOI: 10.1016/S0003-9993(97)90013-7  0.144
1977 GIPON L, SCHOTMAN P, JENNEKENS FGI, GISPEN WH. POLYNEUROPATHIES AND CNS PROTEIN METABOLISM. I. DESCRIPTION OF THE ACRYLAMIDE SYNDROME IN RATS Neuropathology and Applied Neurobiology. 3: 115-123. DOI: 10.1111/j.1365-2990.1977.tb00575.x  0.144
1982 Oestreicher AB, Zwiers H, Gispen WH, Roberts S. Characterization of infant rat cerebral cortical membrane proteins phosphorylated in vivo: identification of the ACTH-sensitive phosphoprotein B-50. Journal of Neurochemistry. 39: 683-92. PMID 6284876 DOI: 10.1111/J.1471-4159.1982.Tb07947.X  0.144
1996 Van Buren T, Kappelle AC, Kasbergen CM, Gispen WH, De Wildt DJ. A disturbed macrocirculatory supply as a determinant for a reduced sciatic nerve blood flow in diabetic rats. European Journal of Pharmacology. 318: 73-80. PMID 9007515 DOI: 10.1016/S0014-2999(96)00775-3  0.144
1989 Oestreicher AB, De Graan PN, Schrama LH, Lamme VA, Bloemen RJ, Schotman P, Gispen WH. The protein kinase C phosphosite(s) in B-50 (GAP-43) are confined to 15K phosphofragments produced by Staphylococcus aureus V8 protease. Neurochemistry International. 14: 361-72. PMID 20504438 DOI: 10.1016/0197-0186(89)90063-6  0.143
1990 Dokas LA, Pisano MR, Schrama LH, Zwiers H, Gispen WH. Dephosphorylation of B-50 in synaptic plasma membranes. Brain Research Bulletin. 24: 321-9. PMID 2159832 DOI: 10.1016/0361-9230(90)90086-F  0.142
2004 Sajti E, van Meeteren N, Kavelaars A, van der Net J, Gispen WH, Heijnen C. Individual differences in behavior of inbred Lewis rats are associated with severity of joint destruction in adjuvant-induced arthritis. Brain, Behavior, and Immunity. 18: 505-14. PMID 15331121 DOI: 10.1016/j.bbi.2003.12.004  0.142
1986 Spruijt BM, Cools AR, Gispen WH. The periaqueductal gray: a prerequisite for ACTH-induced excessive grooming. Behavioural Brain Research. 20: 19-25. PMID 3013234 DOI: 10.1016/0166-4328(86)90097-5  0.142
1981 Aloyo VJ, Zwiers H, Bär PR, Gispen WH. ACTH SOLUBILIZATION OF A KINASE FROM RAT BRAIN SYNAPTOSOMAL PLASMA MEMBRANES Biochemical Society Transactions. 9: 356P-356P. DOI: 10.1042/bst009356pa  0.141
1993 Bär PR, Mandys V, Turecek R, Gispen WH. Alpha-melanocyte-stimulating hormone has protective properties against the toxic effect of cisplatin on cultured dorsal root ganglia. Annals of the New York Academy of Sciences. 680: 649-51. PMID 8390209  0.141
1990 De Graan PN, Oestreicher AB, De Wit M, Kroef M, Schrama LH, Gispen WH. Evidence for the binding of calmodulin to endogenous B-50 (GAP-43) in native synaptosomal plasma membranes. Journal of Neurochemistry. 55: 2139-41. PMID 2146368  0.141
2003 Kamal A, Ramakers GM, Biessels GJ, Gispen WH. Effects of a phorbol ester and cyclosporin A on hippocampal synaptic plasticity in streptozotocin-induced-diabetic rats: reduced sensitivity to phorbol esters. Neuroscience Letters. 339: 45-8. PMID 12618297 DOI: 10.1016/S0304-3940(02)01451-9  0.14
2003 Kamal A, Artola A, Biessels GJ, Gispen WH, Ramakers GM. Increased spike broadening and slow afterhyperpolarization in CA1 pyramidal cells of streptozotocin-induced diabetic rats. Neuroscience. 118: 577-83. PMID 12699792 DOI: 10.1016/S0306-4522(02)00874-6  0.14
2006 Dijkstra S, Duis S, Pans IM, Lankhorst AJ, Hamers FP, Veldman H, Bär PR, Gispen WH, Joosten EA, Geisert EE. Intraspinal administration of an antibody against CD81 enhances functional recovery and tissue sparing after experimental spinal cord injury. Experimental Neurology. 202: 57-66. PMID 16806185 DOI: 10.1016/J.Expneurol.2006.05.011  0.14
1999 Di Luca M, Ruts L, Gardoni F, Cattabeni F, Biessels GJ, Gispen WH. NMDA receptor subunits are modified transcriptionally and post-translationally in the brain of streptozotocin-diabetic rats. Diabetologia. 42: 693-701. PMID 10382589 DOI: 10.1007/s001250051217  0.139
1986 van Dongen CJ, Kok JW, Schrama LH, Oestreicher AB, Gispen WH. Immunochemical characterization of phosphatidylinositol 4-phosphate kinase from rat brain. The Biochemical Journal. 233: 859-64. PMID 3010943 DOI: 10.1042/BJ2330859  0.139
1999 Biessels GJ, Cristino NA, Rutten GJ, Hamers FP, Erkelens DW, Gispen WH. Neurophysiological changes in the central and peripheral nervous system of streptozotocin-diabetic rats. Course of development and effects of insulin treatment. Brain : a Journal of Neurology. 122: 757-68. PMID 10219786 DOI: 10.1093/brain/122.4.757  0.139
1993 Hens JJ, Ghijsen WE, Dimjati W, Wiegant VM, Oestreicher AB, Gispen WH, De Graan PN. Evidence for a role of protein kinase C substrate B-50 (GAP-43) in Ca(2+)-induced neuropeptide cholecystokinin-8 release from permeated synaptosomes. Journal of Neurochemistry. 61: 602-9. PMID 8336144  0.138
2012 Kamal A, Ramakers GM, Gispen WH, Biessels GJ. Effect of chronic intracerebroventricular insulin administration in rats on the peripheral glucose metabolism and synaptic plasticity of CA1 hippocampal neurons. Brain Research. 1435: 99-104. PMID 22206925 DOI: 10.1016/j.brainres.2011.11.057  0.137
1994 Gispen WH, Hamers FP. Calcium and neuronal dysfunction in peripheral nervous system. Annals of the New York Academy of Sciences. 747: 419-30. PMID 7847688  0.137
2003 Manschot SM, Gispen WH, Kappelle LJ, Biessels GJ. Nerve conduction velocity and evoked potential latencies in streptozotocin-diabetic rats: effects of treatment with an angiotensin converting enzyme inhibitor. Diabetes/Metabolism Research and Reviews. 19: 469-77. PMID 14648806 DOI: 10.1002/Dmrr.401  0.137
1988 Isaacson RL, Danks AM, Brakkee J, Schefman K, Gispen WH. Excessive grooming induced by the administration of codeine and morphine. Behavioral and Neural Biology. 50: 37-45. PMID 3401196 DOI: 10.1016/S0163-1047(88)90756-X  0.136
1994 Adan RA, Cone RD, Burbach JP, Gispen WH. Differential effects of melanocortin peptides on neural melanocortin receptors. Molecular Pharmacology. 46: 1182-90. PMID 7808440  0.136
1990 Van der Zee CE, Van den Buuse M, Gispen WH. Beneficial effect of an ACTH-(4-9) analog on peripheral neuropathy and blood pressure response to tyramine in streptozocin diabetic rats. European Journal of Pharmacology. 177: 211-3. PMID 2155811 DOI: 10.1016/0014-2999(90)90273-9  0.136
1998 Hens JJ, De Wit M, Ghijsen WE, Leenders AG, Boddeke HW, Kissmehl R, Wiegant VM, Weller U, Gispen WH, De Graan PN. Role of calcineurin in Ca2+-induced release of catecholamines and neuropeptides. Journal of Neurochemistry. 71: 1978-86. PMID 9798922  0.135
1996 van Dam PS, Bravenboer B, van Asbeck BS, van Oirschot JF, Marx JJ, Gispen WH. Effects of insulin treatment on endoneurial and systemic oxidative stress in relation to nerve conduction in streptozotocin-diabetic rats. European Journal of Clinical Investigation. 26: 1143-9. PMID 9013090  0.135
1996 van Meeteren NL, Brakkee JH, Biessels GJ, Kappelle AC, Helders PJ, Gispen WH. Effect of exercise training on acute (crush lesion) and chronic (diabetes mellitus) peripheral neuropathy in the rat. Restorative Neurology and Neuroscience. 10: 85-93. PMID 21551857 DOI: 10.3233/RNN-1996-10204  0.134
1989 Van Hooff CO, Oestreicher AB, De Graan PN, Gispen WH. Role of the growth cone in neuronal differentiation. Molecular Neurobiology. 3: 101-33. PMID 2679766 DOI: 10.1007/BF02935590  0.134
1998 Sigling HO, Van Engeland H, Gispen WH, Spruijt BM. Attachment in rat pups, an experimental approach Neuroscience Research Communications. 23: 169-179. DOI: 10.1002/(SICI)1520-6769(199811/12)23:3<169::AID-NRC5>3.0.CO;2-W  0.134
1996 Biessels GJ, Stevens EJ, Mahmood SJ, Gispen WH, Tomlinson DR. Insulin partially reverses deficits in peripheral nerve blood flow and conduction in experimental diabetes. Journal of the Neurological Sciences. 140: 12-20. PMID 8866422 DOI: 10.1016/0022-510X(96)00080-9  0.133
2001 Lankhorst AJ, ter Laak MP, van Laar TJ, van Meeteren NL, de Groot JC, Schrama LH, Hamers FP, Gispen WH. Effects of enriched housing on functional recovery after spinal cord contusive injury in the adult rat. Journal of Neurotrauma. 18: 203-15. PMID 11229712 DOI: 10.1089/08977150150502622  0.133
2006 Kamal A, Biessels GJ, Gispen WH, Ramakers GM. Synaptic transmission changes in the pyramidal cells of the hippocampus in streptozotocin-induced diabetes mellitus in rats. Brain Research. 1073: 276-80. PMID 16455062 DOI: 10.1016/j.brainres.2005.12.070  0.132
1999 Oosterom J, Nijenhuis WA, Schaaper WM, Slootstra J, Meloen RH, Gispen WH, Burbach JP, Adan RA. Conformation of the core sequence in melanocortin peptides directs selectivity for the melanocortin MC3 and MC4 receptors. The Journal of Biological Chemistry. 274: 16853-60. PMID 10358030 DOI: 10.1074/jbc.274.24.16853  0.132
1998 Van Buren T, Kasbergen CM, Gispen WH, De Wildt DJ. In vivo cardiovascular reactivity and baroreflex activity in diabetic rats. Cardiovascular Research. 38: 763-71. PMID 9747445 DOI: 10.1016/S0008-6363(98)00038-8  0.131
1984 Jork R, de Graan PN, van Dongen CJ, Zwiers H, Matthies H, Gispen WH. Dopamine-induced changes in protein phosphorylation and polyphosphoinositide metabolism in rat hippocampus. Brain Research. 291: 73-81. PMID 6320956 DOI: 10.1016/0006-8993(84)90652-8  0.13
1998 Mizgalska JA, Berent U, Mac M, Oestreicher AB, De Graan PNE, Gispen WH, Nalȩcz MJ, Nalȩcz KA. Accumulation of palmitoylcarnitine in neuroblastoma NB-2a cells affects the expression, phosphorylation and localization of B-50 protein Neuroscience Research Communications. 22: 73-82. DOI: 10.1002/(SICI)1520-6769(199803/04)22:2<73::AID-NRC2>3.0.CO;2-M  0.129
1984 de Graan PN, van de Kamp AJ, Hup DR, Gispen WH, van de Veerdonk FC. Calcium requirement for alpha-MSH action on melanophores: studies with forskolin. Journal of Receptor Research. 4: 521-36. PMID 6098671 DOI: 10.3109/10799898409042571  0.129
2003 Van Meeteren NL, Eggers R, Lankhorst AJ, Gispen WH, Hamers FP. Locomotor recovery after spinal cord contusion injury in rats is improved by spontaneous exercise. Journal of Neurotrauma. 20: 1029-37. PMID 14588119 DOI: 10.1089/089771503770195876  0.129
2001 Vrinten DH, Kalkman CJ, Adan RA, Gispen WH. Neuropathic pain: a possible role for the melanocortin system? European Journal of Pharmacology. 429: 61-9. PMID 11698027 DOI: 10.1016/S0014-2999(01)01306-1  0.129
2003 Vrinten DH, Gispen WH, Kalkman CJ, Adan RA. Interaction between the spinal melanocortin and opioid systems in a rat model of neuropathic pain. Anesthesiology. 99: 449-54. PMID 12883419 DOI: 10.1097/00000542-200308000-00028  0.128
1987 De Graan PN, Schrama LH, Brussaard AB, Jork R, Gispen WH. 4-Aminopyridine affects synaptosomal protein phosphorylation in rat hippocampal slices. Brain Research. 404: 345-9. PMID 3032338 DOI: 10.1016/0006-8993(87)91392-8  0.128
1980 Bär PR, Schotman P, Gispen WH, Tielen AM, Lopes Da Silva FH. Changes in synaptic membrane phosphorylation after tetanic stimulation in the dentate area of the rat hippocampal slice. Brain Research. 198: 478-84. PMID 7407613  0.128
1996 Biessels G, Gispen WH. The calcium hypothesis of brain aging and neurodegenerative disorders: significance in diabetic neuropathy. Life Sciences. 59: 379-87. PMID 8761325 DOI: 10.1016/0024-3205(96)00316-5  0.127
2002 Starowicz K, Przewlocki R, Gispen WH, Przewlocka B. Modulation of melanocortin-induced changes in spinal nociception by mu-opioid receptor agonist and antagonist in neuropathic rats. Neuroreport. 13: 2447-52. PMID 12499847 DOI: 10.1097/01.wnr.0000047683.08940.57  0.127
1994 Mandys V, Turecek R, Gispen WH, Bär PR. Organotypic cultures of chick dorsal root ganglia in a semi-solid medium: A model for neurotoxicity testing. Toxicology in Vitro : An International Journal Published in Association With Bibra. 8: 81-90. PMID 20692892 DOI: 10.1016/0887-2333(94)90211-9  0.127
1985 de Graan PN, Oestreicher AB, Zwiers H, Gispen WH, van de Veerdonk FC. Characterization of alpha-MSH-induced changes in the phosphorylation of a 53 kDa protein in Xenopus melanophores. Molecular and Cellular Endocrinology. 42: 127-33. PMID 4065423 DOI: 10.1016/0303-7207(85)90100-5  0.127
2000 Ter Laak MP, Lankhorst AJ, Schrama LH, Gispen WH. Neuropathies Neuroscience Research Communications. 26: 227-239. DOI: 10.1002/1520-6769(200005/06)26:3<227::AID-NRC10>3.0.CO;2-B  0.126
2005 Wels B, Kruijtzer JA, Garner K, Nijenhuis WA, Gispen WH, Adan RA, Liskamp RM. Synthesis of a novel potent cyclic peptide MC4-ligand by ring-closing metathesis. Bioorganic & Medicinal Chemistry. 13: 4221-7. PMID 15876540 DOI: 10.1016/J.Bmc.2005.04.027  0.126
1980 Gispen WH, Brakkee JH, Isaacson RL. Hypophysectomy and novelty-induced grooming in the rat. Behavioral and Neural Biology. 29: 481-6. PMID 7447850 DOI: 10.1016/S0163-1047(80)92711-9  0.125
1997 Ramakers GM, Pasinelli P, Hens JJ, Gispen WH, De Graan PN. Protein kinase C in synaptic plasticity: changes in the in situ phosphorylation state of identified pre- and postsynaptic substrates. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 21: 455-86. PMID 9153068 DOI: 10.1016/S0278-5846(97)00013-4  0.125
1983 Hershkowitz M, Zwiers H, Gispen WH. The effect of ACTH on rat brain synaptic plasma membrane lipid fluidity. Biochimica Et Biophysica Acta. 692: 495-7. PMID 6293574 DOI: 10.1016/0005-2736(82)90402-3  0.125
1993 De Graan PN, Gispen WH. The role of B-50/GAP-43 in transmitter release: studies with permeated synaptosomes. Biochemical Society Transactions. 21: 406-10. PMID 8103004  0.125
2001 Hamers FP, Lankhorst AJ, van Laar TJ, Veldhuis WB, Gispen WH. Automated quantitative gait analysis during overground locomotion in the rat: its application to spinal cord contusion and transection injuries. Journal of Neurotrauma. 18: 187-201. PMID 11229711 DOI: 10.1089/08977150150502613  0.124
1986 Schrama LH, De Graan PN, Wadman WJ, Lopes da Silva FH, Gispen WH. Long-term potentiation and 4-aminopyridine-induced changes in protein and lipid phosphorylation in the hippocampal slice. Progress in Brain Research. 69: 245-57. PMID 2833801 DOI: 10.1016/S0079-6123(08)61063-8  0.123
1986 Eichberg J, de Graan PN, Schrama LH, Gispen WH. Dioctanoylglycerol and phorbol diesters enhance phosphorylation of phosphoprotein B-50 in native synaptic plasma membranes. Biochemical and Biophysical Research Communications. 136: 1007-12. PMID 2941012 DOI: 10.1016/0006-291X(86)90433-X  0.123
1995 Ramakers GM, De Graan PN, Urban IJ, Kraay D, Tang T, Pasinelli P, Oestreicher AB, Gispen WH. Temporal differences in the phosphorylation state of pre- and postsynaptic protein kinase C substrates B-50/GAP-43 and neurogranin during long-term potentiation. The Journal of Biological Chemistry. 270: 13892-8. PMID 7775448 DOI: 10.1074/jbc.270.23.13892  0.123
1982 Lopes da Silva FH, Bär PR, Tielen AM, Gispen WH. Changes in membrane phosphorylation correlated with long-lasting potentiation in rat hippocampal slices. Progress in Brain Research. 56: 339-47. PMID 7163505 DOI: 10.1016/S0079-6123(08)63783-8  0.123
2013 Kamal A, Ramakers GM, Gispen WH, Biessels GJ, Al Ansari A. Hyperinsulinemia in rats causes impairment of spatial memory and learning with defects in hippocampal synaptic plasticity by involvement of postsynaptic mechanisms. Experimental Brain Research. 226: 45-51. PMID 23371746 DOI: 10.1007/s00221-013-3409-4  0.122
1992 De Graan P, Gispen W. The role of B-50/GAP-43 in the mechanism of neurotransmitter release Neurochemistry International. 21: S18. DOI: 10.1016/0197-0186(92)91782-R  0.122
1993 Hamers FP, Brakkee JH, Cavalletti E, Tedeschi M, Marmonti L, Pezzoni G, Neijt JP, Gispen WH. Reduced glutathione protects against cisplatin-induced neurotoxicity in rats. Cancer Research. 53: 544-9. PMID 8425186  0.12
2004 Sajti E, Kavelaars A, van Meeteren N, Teunis M, Gispen WH, Heijnen C. Tumor angiogenesis and metastasis formation are associated with individual differences in behavior of inbred Lewis rats. Brain, Behavior, and Immunity. 18: 497-504. PMID 15331120 DOI: 10.1016/j.bbi.2003.11.009  0.12
1987 Spruijt BM, Welbergen P, Brakkee J, Gispen WH. Behavioral changes in ACTH-(1-24)-induced excessive grooming in aging rats. Neurobiology of Aging. 8: 265-70. PMID 3037401 DOI: 10.1016/0197-4580(87)90011-X  0.119
2003 Nijenhuis WA, Kruijtzer JA, Wanders N, Vrinten DH, Garner KM, Schaaper WM, Meloen RH, Gispen WH, Liskamp RM, Adan RA. Discovery and in vivo evaluation of new melanocortin-4 receptor-selective peptides. Peptides. 24: 271-80. PMID 12668212 DOI: 10.1016/S0196-9781(03)00032-9  0.119
1999 Kamal A, Ramakers GM, Urban IJ, De Graan PN, Gispen WH. Chemical LTD in the CA1 field of the hippocampus from young and mature rats. The European Journal of Neuroscience. 11: 3512-6. PMID 10564359  0.119
1978 Colbern DL, Isaacson RL, Green EJ, Gispen WH. Repeated intraventricular injections of ACTH 1-24: the effects of home or novel environments on excessive grooming. Behavioral Biology. 23: 381-7. PMID 212007 DOI: 10.1016/S0091-6773(78)91407-4  0.118
1986 Spruijt BM, Hoglund U, Gispen WH, Meyerson BJ. Effects of ACTH1-24 on male rat behavior in an exploratory, copulatory and socio-sexual approach test. Psychoneuroendocrinology. 10: 431-8. PMID 3003775 DOI: 10.1016/0306-4530(85)90082-4  0.118
2000 Gispen WH. [Nobel prize in physiology of medicine for year 2000 for research of signal transduction in the nervous system]. Nederlands Tijdschrift Voor Geneeskunde. 144: 2184-7. PMID 11103253  0.118
1990 De Graan PN, Schrama LH, Heemskerk FM, Dekker LV, Gispen WH. The role of protein kinase C substrate B-50 (GAP-43) in neurotransmitter release and long-term potentiation. Advances in Experimental Medicine and Biology. 268: 347-58. PMID 1981651 DOI: 10.1007/978-1-4684-5769-8_38  0.117
2002 van Dam EJ, Ruiter B, Kamal A, Ramakers GM, Gispen WH, de Graan PN. N-methyl-D-aspartate-induced long-term depression is associated with a decrease in postsynaptic protein kinase C substrate phosphorylation in rat hippocampal slices. Neuroscience Letters. 320: 129-32. PMID 11852179 DOI: 10.1016/S0304-3940(02)00037-X  0.117
1988 Spruijt BM, Welbergen P, Brakkee J, Gispen WH. An ethological analysis of excessive grooming in young and aged rats. Annals of the New York Academy of Sciences. 525: 89-100. PMID 2839073 DOI: 10.1111/j.1749-6632.1988.tb38598.x  0.116
2006 Artola A, von Frijtag JC, Fermont PC, Gispen WH, Schrama LH, Kamal A, Spruijt BM. Long-lasting modulation of the induction of LTD and LTP in rat hippocampal CA1 by behavioural stress and environmental enrichment. The European Journal of Neuroscience. 23: 261-72. PMID 16420435 DOI: 10.1111/j.1460-9568.2005.04552.x  0.116
1984 Dokas LA, Zwiers H, Gispen WH. Alteration of hippocampal B50 phosphorylation after adrenalectomy. Brain Research Bulletin. 13: 33-8. PMID 6478268 DOI: 10.1016/0361-9230(84)90004-2  0.115
1996 van de Meent H, Hamers FP, Lankhorst AJ, Buise MP, Joosten EA, Gispen WH. New assessment techniques for evaluation of posttraumatic spinal cord function in the rat. Journal of Neurotrauma. 13: 741-54. PMID 9002060  0.115
1996 Biessels GJ, Kamal A, Ramakers GM, Urban IJ, Spruijt BM, Erkelens DW, Gispen WH. Place learning and hippocampal synaptic plasticity in streptozotocin-induced diabetic rats. Diabetes. 45: 1259-66. PMID 8772732  0.114
1974 Schotman P, Gipon L, Gispen WH. Conversion of (4,5-3H)leucine into 3H2O and tritiated metabolites and brain tissue. Comparison of a peripheral and intracranial route of administration. Brain Research. 70: 377-80. PMID 4406419 DOI: 10.1016/0006-8993(74)90330-8  0.114
1988 Isaacson RL, Danks AM, Oestreicher AB, Brakkee JH, Gispen WH. Spontaneous bodily rotations and direction of locomotion at different times after radio frequency lesions at sites in and near the substantia nigra. Physiology & Behavior. 44: 199-204. PMID 3237825 DOI: 10.1016/0031-9384(88)90138-2  0.114
1993 Gispen WH. Neuronal plasticity and function. Clinical Neuropharmacology. 16: S5-11. PMID 8519003  0.113
2000 Rousseau JB, Van Lochem PB, Gispen WH, Spruijt BM. Classification of rat behavior with an image-processing method and a neural network. Behavior Research Methods, Instruments, & Computers : a Journal of the Psychonomic Society, Inc. 32: 63-71. PMID 10758665  0.113
1991 Heemskerk FM, Schrama LH, Ghijsen WE, De Graan PN, Lopes da Silva FH, Gispen WH. Presynaptic mechanism of action of 4-aminopyridine: changes in intracellular free Ca2+ concentration and its relationship to B-50 (GAP-43) phosphorylation. Journal of Neurochemistry. 56: 1827-35. PMID 1851203  0.113
2002 Biessels GJ, ter Laak MP, Hamers FP, Gispen WH. Neuronal Ca2+ disregulation in diabetes mellitus. European Journal of Pharmacology. 447: 201-9. PMID 12151012 DOI: 10.1016/S0014-2999(02)01844-7  0.113
2003 Kamphuis PJ, Gardoni F, Kamal A, Croiset G, Bakker JM, Cattabeni F, Gispen WH, van Bel F, Di Luca M, Wiegant VM. Long-lasting effects of neonatal dexamethasone treatment on spatial learning and hippocampal synaptic plasticity: involvement of the NMDA receptor complex. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 911-3. PMID 12626441 DOI: 10.1096/fj.02-0333fje  0.113
2001 Oosterom J, Garner KM, den Dekker WK, Nijenhuis WA, Gispen WH, Burbach JP, Barsh GS, Adan RA. Common requirements for melanocortin-4 receptor selectivity of structurally unrelated melanocortin agonist and endogenous antagonist, Agouti protein. The Journal of Biological Chemistry. 276: 931-6. PMID 11024027 DOI: 10.1074/jbc.M007261200  0.113
1982 Bär PR, Tielen AM, Lopes Da Silva FH, Zwiers H, Gispen WH. Membrane phosphoproteins of rat hippocampus: sensitivity to tetanic stimulation and enkephalin. Brain Research. 245: 69-79. PMID 6288196  0.112
1998 Van Buren T, Schiereck P, De Ruiter GJ, Gispen WH, De Wildt DJ. Vagal efferent control of electrical properties of the heart in experimental diabetes. Acta Diabetologica. 35: 19-25. PMID 9625285 DOI: 10.1007/s005920050096  0.112
1977 Gispen WH, Perumal R, Wilson JE, Glassman E. Phosphorylation of proteins of synaptosome-enriched fractions of brain during short-term training experience: the effects of various behavioral treatments. Behavioral Biology. 21: 358-63. PMID 921679 DOI: 10.1016/S0091-6773(77)90146-8  0.111
1997 Maaswinkel H, Gispen WH, Spruijt BM. Executive function of the hippocampus in social behavior in the rat. Behavioral Neuroscience. 111: 777-84. PMID 9267654 DOI: 10.1037/0735-7044.111.4.777  0.111
1993 Florijn WJ, Hens JJ, de Graan PN, Versteeg DH, Gispen WH. Effects of ACTH-(1-24) on dopamine and noradrenaline release, B-50 phosphorylation and calmodulin binding to B-50 in vitro. Life Sciences. 52: 1013-22. PMID 8445991 DOI: 10.1016/0024-3205(93)90193-7  0.11
1984 Bär PR, Wiegant F, Lopes da Silva FH, Gispen WH. Tetanic stimulation affects the metabolism of phosphoinositides in hippocampal slices. Brain Research. 321: 381-5. PMID 6093940  0.11
1995 van Buren T, Kasbergen C, Gispen W, de Wildt D. Improvement of macrocirculatory flow responsiveness by the neuroprotective action of the ACTH4–9analogue ORG 2766 in diabetic rats Pharmacological Research. 31: 239. DOI: 10.1016/1043-6618(95)87214-0  0.11
1998 Kamal A, Biessels GJ, Gispen WH, Urban IJ. Increasing age reduces expression of long-term depression and dynamic range of transmission plasticity in CA1 field of the rat hippocampus. Neuroscience. 83: 707-15. PMID 9483555 DOI: 10.1016/S0306-4522(97)00394-1  0.11
1986 Gispen WH. Phosphoprotein B-50 and phosphoinositides in brain synaptic plasma membranes: a possible feedback relationship. Biochemical Society Transactions. 14: 163-5. PMID 3007235 DOI: 10.1042/BST0140163  0.11
1995 Pasinelli P, Ramakers GM, Urban IJ, Hens JJ, Oestreicher AB, de Graan PN, Gispen WH. Long-term potentiation and synaptic protein phosphorylation. Behavioural Brain Research. 66: 53-9. PMID 7755899 DOI: 10.1016/0166-4328(94)00124-X  0.109
1993 Hens JJ, Benfenati F, Nielander HB, Valtorta F, Gispen WH, De Graan PN. B-50/GAP-43 binds to actin filaments without affecting actin polymerization and filament organization. Journal of Neurochemistry. 61: 1530-3. PMID 8377002 DOI: 10.1111/J.1471-4159.1993.Tb13649.X  0.109
2008 Manschot SM, Biessels GJ, Rutten GE, Kessels RP, Kessels RC, Gispen WH, Kappelle LJ. Peripheral and central neurologic complications in type 2 diabetes mellitus: no association in individual patients. Journal of the Neurological Sciences. 264: 157-62. PMID 17850822 DOI: 10.1016/j.jns.2007.08.011  0.108
1983 Oestreicher AB, Zwiers H, Gispen WH. Synaptic membrane phosphorylation: target for neurotransmitters and peptides. Progress in Brain Research. 55: 349-67. PMID 6131478 DOI: 10.1016/S0079-6123(08)64208-9  0.107
1981 Wiegant VM, Zwiers H, Gispen WH. Neuropeptides and brain cAMP and phosphoproteins. Pharmacology & Therapeutics. 12: 463-90. PMID 6269125 DOI: 10.1016/0163-7258(81)90093-0  0.107
1984 Van Dongen CJ, Zwiers H, Gispen WH. Purification and partial characterization of the phosphatidylinositol 4-phosphate kinase from rat brain. The Biochemical Journal. 223: 197-203. PMID 6093768 DOI: 10.1042/BJ2230197  0.106
1996 Vandertop WP, de Vries WB, Notermans NC, Nijsen MJ, de Wildt DJ, Tulleken CA, Gispen WH. Cisplatin-induced autonomic neuropathy: does it really exist? Journal of Neuro-Oncology. 27: 53-60. PMID 8699226  0.106
2010 Merkestein M, Gispen WH, Adan RAH. Melanocortins: Brain Effects Encyclopedia of Neuroscience. 713-719. DOI: 10.1016/B978-008045046-9.01448-0  0.105
2002 Biessels GJ, van der Heide LP, Kamal A, Bleys RL, Gispen WH. Ageing and diabetes: implications for brain function. European Journal of Pharmacology. 441: 1-14. PMID 12007915 DOI: 10.1016/S0014-2999(02)01486-3  0.105
1977 Wiegant VM, Cools AR, Gispen WH. ACTH-induced excessive grooming involves brain dopamine. European Journal of Pharmacology. 41: 343-5. PMID 190018 DOI: 10.1016/0014-2999(77)90330-2  0.104
1986 De Graan PN, Oestreicher AB, Schrama LH, Gispen WH. Phosphoprotein B-50: localization and function. Progress in Brain Research. 69: 37-50. PMID 2965821 DOI: 10.1016/S0079-6123(08)61047-X  0.104
1985 Gispen WH, Schrama LH, Eichberg J. Stimulation of protein kinase C reduces ACTH-induced excessive grooming European Journal of Pharmacology. 114: 399-400. PMID 2998817 DOI: 10.1016/0014-2999(85)90387-5  0.103
1993 Hens JJ, De Wit M, Dekker LV, Boomsma F, Oestreicher AB, Margolis F, Gispen WH, De Graan PN. Studies on the role of B-50 (GAP-43) in the mechanism of Ca(2+)-induced noradrenaline release: lack of involvement of protein kinase C after the Ca2+ trigger. Journal of Neurochemistry. 60: 1264-73. PMID 8455026 DOI: 10.1111/J.1471-4159.1993.Tb03286.X  0.103
1990 Pitsikas N, Spruijt BM, Algeri S, Gispen WH. The ACTH/MSH (4-9) analog Org2766 improves retrieval of information after a fimbria fornix transection. Peptides. 11: 911-4. PMID 2178248  0.102
1994 Kappelle AC, Biessels G, Van Buren T, Bravenboer B, De Wildt DJ, Gispen WH. The effect of diabetes mellitus on development of autonomic neuropathy in the rat: Beneficial effects of the ACTH4-9 analogue Org 2766 on existing diabetic neuropathy Diabetes, Nutrition and Metabolism - Clinical and Experimental. 7: 63-70.  0.101
1996 van Rijzingen IM, Gispen WH, Dam R, Spruijt BM. Chronic and intra-amygdala administrations of the ACTH(4-9) analog ORG 2766 modulate behavioral changes after manipulation of NMDA-receptor activity. Brain Research. 717: 200-3. PMID 8738274 DOI: 10.1016/0006-8993(96)00128-X  0.101
2000 Dijkstra S, Geisert EE JR, Gispen WH, Bär PR, Joosten EA. Up-regulation of CD81 (target of the antiproliferative antibody; TAPA) by reactive microglia and astrocytes after spinal cord injury in the rat. The Journal of Comparative Neurology. 428: 266-77. PMID 11064366 DOI: 10.1002/1096-9861(20001211)428:2<266::Aid-Cne6>3.0.Co;2-0  0.099
1992 Moritz A, De Graan PN, Gispen WH, Wirtz KW. Phosphatidic acid is a specific activator of phosphatidylinositol-4-phosphate kinase. The Journal of Biological Chemistry. 267: 7207-10. PMID 1313792  0.099
1993 Van Doremalen E, Gispen W, Spruijt B. Individual housing partially compensates/facilitates performance in a spatial orientation task in both hippocampal damaged and intact rats Behavioural Processes. 29: 150-151. DOI: 10.1016/0376-6357(93)90076-4  0.098
1975 Perumal R, Gispen WH, Wilson JE, Glassman E. Phosphorylation of Proteins from the Brains of Mice Subjected to Short-term Behavioral Experiences Progress in Brain Research. 42: 201-207. PMID 1197722 DOI: 10.1016/S0079-6123(08)63661-4  0.098
1998 Biessels GJ, Kamal A, Urban IJ, Spruijt BM, Erkelens DW, Gispen WH. Water maze learning and hippocampal synaptic plasticity in streptozotocin-diabetic rats: effects of insulin treatment. Brain Research. 800: 125-35. PMID 9685609 DOI: 10.1016/S0006-8993(98)00510-1  0.096
2003 Manschot SM, Biessels GJ, Cameron NE, Cotter MA, Kamal A, Kappelle LJ, Gispen WH. Angiotensin converting enzyme inhibition partially prevents deficits in water maze performance, hippocampal synaptic plasticity and cerebral blood flow in streptozotocin-diabetic rats. Brain Research. 966: 274-82. PMID 12618350 DOI: 10.1016/S0006-8993(02)04211-7  0.095
2000 Gispen WH, Biessels GJ. Cognition and synaptic plasticity in diabetes mellitus. Trends in Neurosciences. 23: 542-9. PMID 11074263 DOI: 10.1016/S0166-2236(00)01656-8  0.094
1982 Wiegant VM, Reul JM, Gispen WH. Modulation of adenylate cyclase by protein phosphorylation: effects of ACTH. Progress in Brain Research. 56: 397-404. PMID 6298876 DOI: 10.1016/S0079-6123(08)63786-3  0.094
1994 Bravenboer B, Hendrikse PH, Oey PL, van Huffelen AC, Groenhout C, Gispen WH, Erkelens DW. Randomized double-blind placebo-controlled trial to evaluate the effect of the ACTH4-9 analogue ORG 2766 in IDDM patients with neuropathy. Diabetologia. 37: 408-13. PMID 8063043  0.094
2002 Proper EA, Hoogland G, Kappen SM, Jansen GH, Rensen MG, Schrama LH, van Veelen CW, van Rijen PC, van Nieuwenhuizen O, Gispen WH, de Graan PN. Distribution of glutamate transporters in the hippocampus of patients with pharmaco-resistant temporal lobe epilepsy. Brain : a Journal of Neurology. 125: 32-43. PMID 11834591  0.093
1977 Perumal R, Gispen WH, Glassman E, Wilson JE. Phosphorylation of proteins of synaptosome-enriched fractions of brain during short-term training experience: biochemical characterization. Behavioral Biology. 21: 341-57. PMID 921678 DOI: 10.1016/S0091-6773(77)90131-6  0.093
1998 Van Buren T, Vleeming W, Krutzen MM, Van de Kuil T, Gispen WH, De Wildt DJ. Vascular responses of isolated mesenteric resistance and basilar arteries from short- and long-term diabetic rats. Naunyn-Schmiedeberg's Archives of Pharmacology. 358: 663-70. PMID 9879726  0.093
1997 Adan RA, Gispen WH. Brain melanocortin receptors: from cloning to function. Peptides. 18: 1279-87. PMID 9396074 DOI: 10.1016/S0196-9781(97)00078-8  0.092
2001 Biessels GJ, Braun KP, de Graaf RA, van Eijsden P, Gispen WH, Nicolay K. Cerebral metabolism in streptozotocin-diabetic rats: an in vivo magnetic resonance spectroscopy study. Diabetologia. 44: 346-53. PMID 11317667 DOI: 10.1007/S001250051625  0.092
1986 Gispen WH, De Graan PN, Chan SY, Routtenberg A. Comparison between the neural acidic proteins B-50 and F1. Progress in Brain Research. 69: 383-6. PMID 2965822 DOI: 10.1016/S0079-6123(08)61072-9  0.09
2006 Jirsova K, Mandys V, Gispen WH, Bär PR. Cisplatin-induced apoptosis in cultures of human Schwann cells. Neuroscience Letters. 392: 22-6. PMID 16236448 DOI: 10.1016/j.neulet.2005.08.068  0.09
1998 Houweling DA, Bär PR, Gispen WH, Joosten EA. Spinal cord injury: bridging the lesion and the role of neurotrophic factors in repair. Progress in Brain Research. 117: 455-71. PMID 9932425  0.089
2000 Kamal A, Biessels GJ, Duis SE, Gispen WH. Learning and hippocampal synaptic plasticity in streptozotocin-diabetic rats: interaction of diabetes and ageing. Diabetologia. 43: 500-6. PMID 10819245 DOI: 10.1007/s001250051335  0.089
1998 Oosterom J, Burbach JP, Gispen WH, Adan RA. Asp10 in Lys-gamma2-MSH determines selective activation of the melanocortin MC3 receptor. European Journal of Pharmacology. 354: R9-11. PMID 9726642 DOI: 10.1016/S0014-2999(98)00491-9  0.089
1979 Gispen WH, Zwiers H, Wiegant VM, Schotman P, Wilson JE. The behaviorally active neuropeptide ACTH as neurohormone and neuromodulator: the role of cyclic nucleotides and membrane phosphoproteins. Advances in Experimental Medicine and Biology. 116: 199-224. PMID 224670 DOI: 10.1007/978-1-4684-3503-0_11  0.088
2001 Popoviç M, Biessels GJ, Isaacson RL, Gispen WH. Learning and memory in streptozotocin-induced diabetic rats in a novel spatial/object discrimination task. Behavioural Brain Research. 122: 201-7. PMID 11334650 DOI: 10.1016/S0166-4328(01)00186-3  0.087
1995 Verhage M, Hens JJ, De Grann PN, Boomsma F, Wiegant VM, da Silva FH, Gispen WH, Ghijsen WE. Ba2+ replaces Ca2+/calmodulin in the activation of protein phosphatases and in exocytosis of all major transmitters. European Journal of Pharmacology. 291: 387-98. PMID 8719425 DOI: 10.1016/0922-4106(95)90081-0  0.087
1981 Gispen WH. On the neurochemical mechanism of action of ACTH. Progress in Brain Research. 53: 193-206. PMID 6109359 DOI: 10.1016/S0079-6123(08)60065-5  0.086
1992 Bär P, Renkema H, Gispen W. Nimodipin restores normal neurite outgrowth after a depolarisation-induced disturbance of calcium homeostasis Neurochemistry International. 21: A3. DOI: 10.1016/0197-0186(92)91905-C  0.085
2005 van der Heide LP, Kamal A, Artola A, Gispen WH, Ramakers GM. Insulin modulates hippocampal activity-dependent synaptic plasticity in a N-methyl-d-aspartate receptor and phosphatidyl-inositol-3-kinase-dependent manner. Journal of Neurochemistry. 94: 1158-66. PMID 16092951 DOI: 10.1111/j.1471-4159.2005.03269.x  0.083
1984 Verhallen PF, Demel RA, Zwiers H, Gispen WH. Adrenocorticotropic hormone (ACTH)-lipid interactions. Implications for involvement of amphipathic helix formation. Biochimica Et Biophysica Acta. 775: 246-54. PMID 6087904 DOI: 10.1016/0005-2736(84)90176-7  0.082
1984 Gispen WH. Neuropeptides and behavior: ACTH. Scandinavian Journal of Psychology. 16-25. PMID 6322288 DOI: 10.1111/J.1467-9450.1982.TB00448.X  0.082
1973 Gispen WH, van der Poel AM, Wimersma Greidanus TB. Pituitary-adrenal influences on behavior: responses to test situation with or without electric footshock. Physiology & Behavior. 10: 345-50. PMID 4351700 DOI: 10.1016/0031-9384(73)90320-X  0.081
1999 Kamal A, Biessels GJ, Urban IJ, Gispen WH. Hippocampal synaptic plasticity in streptozotocin-diabetic rats: impairment of long-term potentiation and facilitation of long-term depression. Neuroscience. 90: 737-45. PMID 10218775 DOI: 10.1016/S0306-4522(98)00485-0  0.081
1985 van Dongen CJ, Zwiers H, Gispen WH. Microdetermination of phosphoinositides in a single extract. Analytical Biochemistry. 144: 104-9. PMID 2984954 DOI: 10.1016/0003-2697(85)90090-9  0.081
2005 Artola A, Kamal A, Ramakers GM, Biessels GJ, Gispen WH. Diabetes mellitus concomitantly facilitates the induction of long-term depression and inhibits that of long-term potentiation in hippocampus. The European Journal of Neuroscience. 22: 169-78. PMID 16029206 DOI: 10.1111/j.1460-9568.2005.04205.x  0.08
2001 Veenema HC, van Hooff JA, Gispen WH, Spruijt BM. Increased rigidity with age in social behavior of Java-monkeys (Macaca fascicularis). Neurobiology of Aging. 22: 273-81. PMID 11182477 DOI: 10.1016/S0197-4580(00)00204-9  0.079
2000 Hoogland G, Hens JJ, De Wit M, van Veelen CW, van Huffelen AC, Gispen WH, de Graan PN. Glutamate and gamma-aminobutyric acid content and release of synaptosomes from temporal lobe epilepsy patients. Journal of Neuroscience Research. 60: 686-95. PMID 10820440 DOI: 10.1002/(SICI)1097-4547(20000601)60:5<686::AID-JNR14>3.0.CO;2-P  0.077
1977 SCHOTMAN P, GIPON L, JENNEKENS FGI, GISPEN WH. POLYNEUROPATHIES AND CNS PROTEIN METABOLISM. II. CHANGES IN THE INCORPORATION RATE OF LEUCINE DURING ACRYLAMIDE INTOXICATION Neuropathology and Applied Neurobiology. 3: 125-136. DOI: 10.1111/j.1365-2990.1977.tb00576.x  0.077
1997 Adan RA, Oosterom J, Toonen RF, Kraan MV, Burbach JP, Gispen WH. Molecular pharmacology of neural melanocortin receptors. Receptors & Channels. 5: 215-23. PMID 9606726  0.077
1993 Moritz A, Westerman J, De Graan PN, Payrastre B, Gispen WH, Wirtz KW. Characterization of phosphatidylinositol-4-phosphate 5-kinase activities from bovine brain membranes. Biochimica Et Biophysica Acta. 1168: 79-86. PMID 8389203 DOI: 10.1016/0005-2760(93)90269-F  0.076
1991 Harmers FP, Gispen WH, Neijt JP. Neurotoxic side-effects of cisplatin. European Journal of Cancer (Oxford, England : 1990). 27: 372-6. PMID 1827334  0.075
1993 Gispen WH. The potential of melanotropins in the treatment of nervous system diseases. Annals of the New York Academy of Sciences. 680: 401-11. PMID 8390160  0.075
1972 Gispen WH, Schotman P, de Kloet ER. Brain RNA and hypophysectomy; a topographical study. Neuroendocrinology. 9: 285-96. PMID 5030043 DOI: 10.1159/000122060  0.074
1992 Verhage M, Gispen W, de Graan P. Vasopressin and oxytocin induced elevations of intracellular free Ca2+ in sympathetic ganglia Neurochemistry International. 21: D5. DOI: 10.1016/0197-0186(92)92131-M  0.074
1993 Gispen W. Towards the European Decade of Brain Research European Neuropsychopharmacology. 3: 179-180. DOI: 10.1016/0924-977X(93)90012-B  0.074
1991 Dekker LV, De Graan PN, Gispen WH. Transmitter release: target of regulation by protein kinase C? Progress in Brain Research. 89: 209-33. PMID 1686660  0.072
2003 van der Heide LP, Hoekman MF, Biessels GJ, Gispen WH. Insulin inhibits extracellular regulated kinase 1/2 phosphorylation in a phosphatidylinositol 3-kinase (PI3) kinase-dependent manner in Neuro2a cells. Journal of Neurochemistry. 86: 86-91. PMID 12807428 DOI: 10.1046/j.1471-4159.2003.01828.x  0.071
2004 Biessels GJ, Bravenboer B, Gispen WH. Glucose, insulin and the brain: modulation of cognition and synaptic plasticity in health and disease: a preface. European Journal of Pharmacology. 490: 1-4. PMID 15094068 DOI: 10.1016/j.ejphar.2004.02.057  0.071
1990 Kavelaars A, Eggen BJ, De Graan PN, Gispen WH, Heijnen CJ. The phosphorylation of the CD3 gamma chain of T lymphocytes is modulated by beta-endorphin. European Journal of Immunology. 20: 943-5. PMID 2140792 DOI: 10.1002/eji.1830200435  0.07
2001 Proper EA, Jansen GH, van Veelen CW, van Rijen PC, Gispen WH, de Graan PN. A grading system for hippocampal sclerosis based on the degree of hippocampal mossy fiber sprouting. Acta Neuropathologica. 101: 405-9. PMID 11355312  0.068
1984 Spruijt BM, Gispen WH. Prolonged animal observation by use of digitized videodisplays. Pharmacology, Biochemistry, and Behavior. 19: 765-9. PMID 6647510 DOI: 10.1016/0091-3057(83)90077-1  0.068
1987 Spruijt B, Gispen W. 79. Effects of ACTH(4–9) on age-related behavioral changes Clinical Neurology and Neurosurgery. 89: 28-29. DOI: 10.1016/0303-8467(87)90079-5  0.065
2002 Artola A, Kamal A, Ramakers GM, Gardoni F, Di Luca M, Biessels GJ, Cattabeni F, Gispen WH. Synaptic plasticity in the diabetic brain: advanced aging? Progress in Brain Research. 138: 305-14. PMID 12432776 DOI: 10.1016/S0079-6123(02)38084-1  0.065
1999 Kamal A, Spoelstra K, Biessels GJ, Urban IJ, Gispen WH. Effects of changes in glucose concentration on synaptic plasticity in hippocampal slices. Brain Research. 824: 238-42. PMID 10196454 DOI: 10.1016/S0006-8993(99)01215-9  0.064
1992 Bravenboer B, Erkelens DW, Gispen WH. Rationale for the use of the ACTH4-9 analogue ORG 2766 in the treatment of diabetic neuropathy. The Netherlands Journal of Medicine. 41: 255-8. PMID 1337372  0.064
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