| Year |
Citation |
Score |
| 2024 |
Stoolman JS, Grant RA, Poor TA, Weinberg SE, D'Alessandro KB, Tan J, Hu JY, Zerrer ME, Wood WA, Harding MC, Soni S, Ridge KM, Schumacker PT, Budinger GRS, Chandel NS. Mitochondrial respiration in microglia is essential for response to demyelinating injury but not proliferation. Nature Metabolism. PMID 39048801 DOI: 10.1038/s42255-024-01080-1 |
0.305 |
|
| 2024 |
Granat L, Knorr DY, Ranson DC, Chakrabarty RP, Chandel NS, Bateman JM. A Drosophila model of mitochondrial disease phenotypic heterogeneity. Biology Open. PMID 38304969 DOI: 10.1242/bio.060278 |
0.314 |
|
| 2023 |
Meade N, Toreev HK, Chakrabarty RP, Hesser CR, Park C, Chandel NS, Walsh D. The poxvirus F17 protein counteracts mitochondrially orchestrated antiviral responses. Nature Communications. 14: 7889. PMID 38036506 DOI: 10.1038/s41467-023-43635-y |
0.309 |
|
| 2023 |
Han S, Lee M, Shin Y, Giovanni R, Chakrabarty RP, Herrerias MM, Dada LA, Flozak AS, Reyfman PA, Khuder B, Reczek CR, Gao L, Lopéz-Barneo J, Gottardi CJ, Budinger GRS, ... Chandel NS, et al. Mitochondrial integrated stress response controls lung epithelial cell fate. Nature. PMID 37558881 DOI: 10.1038/s41586-023-06423-8 |
0.368 |
|
| 2023 |
Granat L, Knorr DY, Ranson DC, Hamer EL, Chakrabarty RP, Mattedi F, Fort-Aznar L, Hirth F, Sweeney ST, Vagnoni A, Chandel NS, Bateman JM. Yeast NDI1 reconfigures neuronal metabolism and prevents the unfolded protein response in mitochondrial complex I deficiency. Plos Genetics. 19: e1010793. PMID 37399212 DOI: 10.1371/journal.pgen.1010793 |
0.305 |
|
| 2023 |
Jiménez-Gómez B, Ortega-Sáenz P, Gao L, González-Rodríguez P, García-Flores P, Chandel N, López-Barneo J. Transgenic NADH dehydrogenase restores oxygen regulation of breathing in mitochondrial complex I-deficient mice. Nature Communications. 14: 1172. PMID 36859533 DOI: 10.1038/s41467-023-36894-2 |
0.359 |
|
| 2023 |
Robertson GL, Riffle S, Patel M, Bodnya C, Marshall A, Beasley HK, Garza-Lopez E, Shao J, Vue Z, Hinton A, Stoll MS, de Wet S, Theart RP, Chakrabarty RP, Loos B, ... Chandel NS, et al. DRP1 mutations associated with EMPF1 encephalopathy alter mitochondrial membrane potential and metabolic programs. Journal of Cell Science. 136. PMID 36763487 DOI: 10.1242/jcs.260370 |
0.347 |
|
| 2022 |
Chakrabarty RP, Chandel NS. Beyond ATP, new roles of mitochondria. The Biochemist. 44: 2-8. PMID 36248614 DOI: 10.1042/bio_2022_119 |
0.342 |
|
| 2022 |
Yuskaitis CJ, Modasia JB, Schrötter S, Rossitto LA, Groff KJ, Morici C, Mithal DS, Chakrabarty RP, Chandel NS, Manning BD, Sahin M. DEPDC5-dependent mTORC1 signaling mechanisms are critical for the anti-seizure effects of acute fasting. Cell Reports. 40: 111278. PMID 36044864 DOI: 10.1016/j.celrep.2022.111278 |
0.691 |
|
| 2022 |
Billingham LK, Stoolman JS, Vasan K, Rodriguez AE, Poor TA, Szibor M, Jacobs HT, Reczek CR, Rashidi A, Zhang P, Miska J, Chandel NS. Mitochondrial electron transport chain is necessary for NLRP3 inflammasome activation. Nature Immunology. PMID 35484407 DOI: 10.1038/s41590-022-01185-3 |
0.364 |
|
| 2022 |
Wang X, Shelton SD, Bordieanu B, Frank AR, Yi Y, Venigalla SSK, Gu Z, Lenser NP, Glogauer M, Chandel NS, Zhao H, Zhao Z, McFadden DG, Mishra P. Scinderin promotes fusion of electron transport chain dysfunctional muscle stem cells with myofibers. Nature Aging. 2: 155-169. PMID 35342888 DOI: 10.1038/s43587-021-00164-x |
0.328 |
|
| 2022 |
Guan N, Kobayashi H, Ishii K, Davidoff O, Sha F, Ikizler TA, Hao CM, Chandel NS, Haase VH. Disruption of mitochondrial complex III in cap mesenchyme but not in ureteric progenitors results in defective nephrogenesis associated with amino acid deficiency. Kidney International. PMID 35341793 DOI: 10.1016/j.kint.2022.02.030 |
0.323 |
|
| 2022 |
Vasan K, Clutter M, Fernandez Dunne S, George MD, Luan CH, Chandel NS, Martínez-Reyes I. Genes Involved in Maintaining Mitochondrial Membrane Potential Upon Electron Transport Chain Disruption. Frontiers in Cell and Developmental Biology. 10: 781558. PMID 35252167 DOI: 10.3389/fcell.2022.781558 |
0.388 |
|
| 2021 |
Mithal DS, Chandel NS. The Gro3p factor: Restoring NAD+/NADH homeostasis to ameliorate mitochondrial disease. Cell Metabolism. 33: 1905-1907. PMID 34614406 DOI: 10.1016/j.cmet.2021.09.006 |
0.762 |
|
| 2021 |
Ma W, Gil HJ, Liu X, Diebold LP, Morgan MA, Oxendine-Burns MJ, Gao P, Chandel NS, Oliver G. Mitochondrial respiration controls the Prox1-Vegfr3 feedback loop during lymphatic endothelial cell fate specification and maintenance. Science Advances. 7. PMID 33931446 DOI: 10.1126/sciadv.abe7359 |
0.339 |
|
| 2021 |
Steinert EM, Vasan K, Chandel NS. Mitochondrial Metabolism Regulation of T Cell-Mediated Immunity. Annual Review of Immunology. 39: 395-416. PMID 33902315 DOI: 10.1146/annurev-immunol-101819-082015 |
0.303 |
|
| 2021 |
Weng X, Kumar A, Cao L, He Y, Morgun E, Visvabharathy L, Zhao J, Sena LA, Weinberg SE, Chandel NS, Wang CR. Mitochondrial metabolism is essential for invariant natural killer T cell development and function. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33753493 DOI: 10.1073/pnas.2021385118 |
0.763 |
|
| 2021 |
Chakrabarty RP, Chandel NS. Mitochondria as Signaling Organelles Control Mammalian Stem Cell Fate. Cell Stem Cell. 28: 394-408. PMID 33667360 DOI: 10.1016/j.stem.2021.02.011 |
0.349 |
|
| 2021 |
Chandel NS. Mitochondria. Cold Spring Harbor Perspectives in Biology. 13. PMID 33649187 DOI: 10.1101/cshperspect.a040543 |
0.309 |
|
| 2021 |
Marinaccio C, Suraneni P, Celik H, Volk A, Wen QJ, Ling T, Bulic M, Lasho T, Koche RP, Famulare CA, Farnoud N, Stein B, Schieber M, Gurbuxani S, Root DE, ... ... Chandel NS, et al. LKB1/STK11 is a tumor suppressor in the progression of myeloproliferative neoplasms. Cancer Discovery. PMID 33579786 DOI: 10.1158/2159-8290.CD-20-1353 |
0.77 |
|
| 2021 |
Mithal DS, Chandel NS. Treating mitochondrial diseases with antibiotics. Nature Metabolism. 3: 5-6. PMID 33462513 DOI: 10.1038/s42255-020-00336-w |
0.737 |
|
| 2020 |
Ishii K, Kobayashi H, Taguchi K, Guan N, Li A, Tong C, Davidoff O, Tran PV, Sharma M, Chandel NS, Kapp ME, Fogo AB, Brooks CR, Haase VH. Kidney epithelial targeted mitochondrial transcription factor A deficiency results in progressive mitochondrial depletion associated with severe cystic disease. Kidney International. PMID 33159962 DOI: 10.1016/j.kint.2020.10.013 |
0.349 |
|
| 2020 |
Mithal DS, Chandel NS. Mitochondrial Dysfunction in Fragile-X Syndrome: Plugging the Leak May Save the Ship. Molecular Cell. 80: 381-383. PMID 33157013 DOI: 10.1016/j.molcel.2020.10.002 |
0.734 |
|
| 2020 |
Kong H, Reczek CR, McElroy GS, Steinert EM, Wang T, Sabatini DM, Chandel NS. Metabolic determinants of cellular fitness dependent on mitochondrial reactive oxygen species. Science Advances. 6. PMID 33148642 DOI: 10.1126/sciadv.abb7272 |
0.428 |
|
| 2020 |
Do-Umehara HC, Chen C, Zhang Q, Misharin AV, Abdala-Valencia H, Casalino-Matsuda SM, Reyfman PA, Anekalla KR, Gonzalez-Gonzalez FJ, Sala MA, Peng C, Wu P, Wong CCL, Kalhan R, Bharat A, ... ... Chandel NS, et al. Epithelial cell-specific loss of function of causes a spontaneous COPD-like phenotype and up-regulates expression in mice. Science Advances. 6: eabb7238. PMID 32851183 DOI: 10.1126/Sciadv.Abb7238 |
0.305 |
|
| 2020 |
Vasan K, Werner M, Chandel NS. Mitochondrial Metabolism as a Target for Cancer Therapy. Cell Metabolism. PMID 32668195 DOI: 10.1016/J.Cmet.2020.06.019 |
0.395 |
|
| 2020 |
Martínez-Reyes I, Cardona LR, Kong H, Vasan K, McElroy GS, Werner M, Kihshen H, Reczek CR, Weinberg SE, Gao P, Steinert EM, Piseaux R, Budinger GRS, Chandel NS. Mitochondrial ubiquinol oxidation is necessary for tumour growth. Nature. PMID 32641834 DOI: 10.1038/S41586-020-2475-6 |
0.428 |
|
| 2020 |
McElroy GS, Reczek CR, Reyfman PA, Mithal DS, Horbinski CM, Chandel NS. NAD+ Regeneration Rescues Lifespan, but Not Ataxia, in a Mouse Model of Brain Mitochondrial Complex I Dysfunction. Cell Metabolism. PMID 32574562 DOI: 10.1016/J.Cmet.2020.06.003 |
0.763 |
|
| 2020 |
Lee P, Chandel NS, Simon MC. Cellular adaptation to hypoxia through hypoxia inducible factors and beyond. Nature Reviews. Molecular Cell Biology. PMID 32144406 DOI: 10.1038/S41580-020-0227-Y |
0.468 |
|
| 2020 |
Kaplan N, Dong Y, Wang S, Yang W, Park JK, Wang J, Fiolek E, Perez White B, Chandel NS, Peng H, Lavker RM. FIH-1 engages novel binding partners to positively influence epithelial proliferation via p63. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 34: 525-539. PMID 31914679 DOI: 10.1096/Fj.201901512R |
0.361 |
|
| 2020 |
Martínez-Reyes I, Chandel NS. Mitochondrial TCA cycle metabolites control physiology and disease. Nature Communications. 11: 102. PMID 31900386 DOI: 10.1038/S41467-019-13668-3 |
0.406 |
|
| 2019 |
Bueno MJ, Jimenez-Renard V, Samino S, Capellades J, Junza A, López-Rodríguez ML, Garcia-Carceles J, Lopez-Fabuel I, Bolaños JP, Chandel NS, Yanes O, Colomer R, Quintela-Fandino M. Essentiality of fatty acid synthase in the 2D to anchorage-independent growth transition in transforming cells. Nature Communications. 10: 5011. PMID 31676791 DOI: 10.1038/S41467-019-13028-1 |
0.345 |
|
| 2019 |
Hunt RJ, Granat L, McElroy GS, Ranganathan R, Chandel NS, Bateman JM. Mitochondrial stress causes neuronal dysfunction via an ATF4-dependent increase in L-2-hydroxyglutarate. The Journal of Cell Biology. PMID 31645461 DOI: 10.1083/Jcb.201904148 |
0.388 |
|
| 2019 |
Zhao Z, Wang L, Bartom E, Marshall S, Rendleman E, Ryan C, Shilati A, Savas J, Chandel N, Shilatifard A. β-Catenin/Tcf7l2-dependent transcriptional regulation of GLUT1 gene expression by Zic family proteins in colon cancer. Science Advances. 5: eaax0698. PMID 31392276 DOI: 10.1126/Sciadv.Aax0698 |
0.335 |
|
| 2019 |
Fu Z, Ye J, Dean JW, Bostick JW, Weinberg SE, Xiong L, Oliff KN, Chen ZE, Avram D, Chandel NS, Zhou L. Requirement of Mitochondrial Transcription Factor A in Tissue-Resident Regulatory T Cell Maintenance and Function. Cell Reports. 28: 159-171.e4. PMID 31269437 DOI: 10.1016/J.Celrep.2019.06.024 |
0.438 |
|
| 2019 |
Stoolman JS, Chandel NS. Glucose Metabolism Linked to Antiviral Responses. Cell. 178: 10-11. PMID 31251910 DOI: 10.1016/J.Cell.2019.05.057 |
0.306 |
|
| 2019 |
Diebold LP, Gil HJ, Gao P, Martinez CA, Weinberg SE, Chandel NS. Mitochondrial complex III is necessary for endothelial cell proliferation during angiogenesis. Nature Metabolism. 1: 158-171. PMID 31106291 DOI: 10.1038/s42255-018-0011-x |
0.329 |
|
| 2019 |
Yao Q, Khan MP, Merceron C, LaGory EL, Tata Z, Mangiavini L, Hu J, Vemulapalli K, Chandel NS, Giaccia AJ, Schipani E. Suppressing Mitochondrial Respiration Is Critical for Hypoxia Tolerance in the Fetal Growth Plate. Developmental Cell. PMID 31105007 DOI: 10.1016/J.Devcel.2019.04.029 |
0.492 |
|
| 2019 |
Singer BD, Chandel NS. Immunometabolism of pro-repair cells. The Journal of Clinical Investigation. 130. PMID 31081802 DOI: 10.1172/Jci124613 |
0.427 |
|
| 2019 |
Miska J, Lee-Chang C, Rashidi A, Muroski ME, Chang AL, Lopez-Rosas A, Zhang P, Panek WK, Cordero A, Han Y, Ahmed AU, Chandel NS, Lesniak MS. HIF-1α Is a Metabolic Switch between Glycolytic-Driven Migration and Oxidative Phosphorylation-Driven Immunosuppression of Tregs in Glioblastoma. Cell Reports. 27: 226-237.e4. PMID 30943404 DOI: 10.1016/J.Celrep.2019.03.029 |
0.385 |
|
| 2019 |
Soberanes S, Misharin AV, Jairaman A, Morales-Nebreda L, McQuattie-Pimentel AC, Cho T, Hamanaka RB, Meliton AY, Reyfman PA, Walter JM, Chen CI, Chi M, Chiu S, Gonzalez-Gonzalez FJ, Antalek M, ... ... Chandel NS, et al. Metformin Targets Mitochondrial Electron Transport to Reduce Air-Pollution-Induced Thrombosis. Cell Metabolism. 29: 503. PMID 30726761 DOI: 10.1016/J.Cmet.2018.12.001 |
0.363 |
|
| 2019 |
Wen YA, Xiong X, Scott T, Li AT, Wang C, Weiss HL, Tan L, Bradford E, Fan TWM, Chandel NS, Barrett TA, Gao T. The mitochondrial retrograde signaling regulates Wnt signaling to promote tumorigenesis in colon cancer. Cell Death and Differentiation. PMID 30659235 DOI: 10.1038/S41418-018-0265-6 |
0.481 |
|
| 2019 |
Weinberg SE, Singer BD, Steinert EM, Martinez CA, Mehta MM, Martínez-Reyes I, Gao P, Helmin KA, Abdala-Valencia H, Sena LA, Schumacker PT, Turka LA, Chandel NS. Mitochondrial complex III is essential for suppressive function of regulatory T cells. Nature. PMID 30626970 DOI: 10.1038/S41586-018-0846-Z |
0.749 |
|
| 2019 |
May JL, Kouri FM, Hurley LA, Liu J, Tommasini-Ghelfi S, Ji Y, Gao P, Calvert AE, Lee A, Chandel NS, Davuluri RV, Horbinski CM, Locasale JW, Stegh AH. IDH3α regulates one-carbon metabolism in glioblastoma. Science Advances. 5: eaat0456. PMID 30613765 DOI: 10.1126/Sciadv.Aat0456 |
0.376 |
|
| 2019 |
McElroy GS, Chandel NS. Probing mitochondrial metabolism in vivo. Proceedings of the National Academy of Sciences of the United States of America. 116: 20-22. PMID 30563855 DOI: 10.1073/Pnas.1819614116 |
0.475 |
|
| 2019 |
Steinert EM, Weinberg SE, Chandel NS. Abstract B067: Distinct necessity of mitochondrial complex I and III for regulatory T-cell function Cancer Immunology Research. 7. DOI: 10.1158/2326-6074.Cricimteatiaacr18-B067 |
0.458 |
|
| 2018 |
Zhang S, Weinberg S, DeBerge M, Gainullina A, Schipma M, Kinchen JM, Ben-Sahra I, Gius DR, Charvet LY, Chandel NS, Schumacker PT, Thorp EB. Efferocytosis Fuels Requirements of Fatty Acid Oxidation and the Electron Transport Chain to Polarize Macrophages for Tissue Repair. Cell Metabolism. PMID 30595481 DOI: 10.1016/J.Cmet.2018.12.004 |
0.362 |
|
| 2018 |
Pusec CM, De Jesus A, Khan MW, Terry AR, Ludvik AE, Xu K, Giancola N, Pervaiz H, Smith ED, Ding X, Harrison S, Chandel NS, Becker TC, Hay N, Ardehali H, et al. Hepatic HKDC1 expression contributes to liver metabolism. Endocrinology. PMID 30517626 DOI: 10.1210/En.2018-00887 |
0.356 |
|
| 2018 |
Soberanes S, Misharin AV, Jairaman A, Morales-Nebreda L, McQuattie-Pimentel AC, Cho T, Hamanaka RB, Meliton AY, Walter JM, Chen CI, Chi M, Chiu S, Gonzalez-Gonzalez FJ, Antalek M, Adbala-Valencia H, ... ... Chandel NS, et al. Metformin Targets Mitochondrial Electron Transport to Reduce Air-Pollution-Induced Thrombosis. Cell Metabolism. PMID 30318339 DOI: 10.1016/J.Cmet.2018.09.019 |
0.351 |
|
| 2018 |
Mehta MM, Weinberg SE, Steinert EM, Chhiba K, Martinez CA, Gao P, Perlman HR, Bryce P, Hay N, Chandel NS. Hexokinase 2 is dispensable for T cell-dependent immunity. Cancer & Metabolism. 6: 10. PMID 30140438 DOI: 10.1186/S40170-018-0184-5 |
0.34 |
|
| 2018 |
Reczek CR, Chandel NS. ROS Promotes Cancer Cell Survival through Calcium Signaling. Cancer Cell. 33: 949-951. PMID 29894695 DOI: 10.1016/J.Ccell.2018.05.010 |
0.443 |
|
| 2018 |
Kong H, Chandel NS. To Claim Growth Turf, mTOR Says SOD Off. Molecular Cell. 70: 383-384. PMID 29727615 DOI: 10.1016/J.Molcel.2018.04.015 |
0.351 |
|
| 2018 |
Martínez-Reyes I, Chandel NS. Acetyl-CoA-directed gene transcription in cancer cells. Genes & Development. 32: 463-465. PMID 29692354 DOI: 10.1101/Gad.315168.118 |
0.332 |
|
| 2018 |
Lozoya OA, Martinez-Reyes I, Wang T, Grenet D, Bushel P, Li J, Chandel N, Woychik RP, Santos JH. Mitochondrial nicotinamide adenine dinucleotide reduced (NADH) oxidation links the tricarboxylic acid (TCA) cycle with methionine metabolism and nuclear DNA methylation. Plos Biology. 16: e2005707. PMID 29668680 DOI: 10.1371/Journal.Pbio.2005707 |
0.42 |
|
| 2018 |
Naguib A, Mathew G, Reczek CR, Watrud K, Ambrico A, Herzka T, Salas IC, Lee MF, El-Amine N, Zheng W, Di Francesco ME, Marszalek JR, Pappin DJ, Chandel NS, Trotman LC. Mitochondrial Complex I Inhibitors Expose a Vulnerability for Selective Killing of Pten-Null Cells. Cell Reports. 23: 58-67. PMID 29617673 DOI: 10.1016/J.Celrep.2018.03.032 |
0.401 |
|
| 2018 |
Steinert EM, Chandel NS. Mitochondria-ER Pas de Deux Controls Memory T Cell Function. Immunity. 48: 479-481. PMID 29562198 DOI: 10.1016/J.Immuni.2018.03.002 |
0.31 |
|
| 2018 |
Galluzzi L, Vitale I, Aaronson SA, Abrams JM, Adam D, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Annicchiarico-Petruzzelli M, Antonov AV, Arama E, Baehrecke EH, Barlev NA, ... ... Chandel NS, et al. Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. Cell Death and Differentiation. PMID 29362479 DOI: 10.1038/S41418-017-0012-4 |
0.413 |
|
| 2018 |
Xu S, Tao J, Yang L, Zhang E, Boriboun C, Zhou J, Sun T, Cheng M, Huang K, Shi J, Dong N, Liu Q, Zhao TC, Qiu H, Harris RA, ... Chandel N, et al. E2F1 Suppresses Oxidative Metabolism and Endothelial Differentiation of Bone Marrow Progenitor Cells. Circulation Research. PMID 29358228 DOI: 10.1161/Circresaha.117.311814 |
0.357 |
|
| 2017 |
Kong H, Chandel NS. Regulation of redox balance in cancer and T cells. The Journal of Biological Chemistry. PMID 29282291 DOI: 10.1074/Jbc.Tm117.000257 |
0.474 |
|
| 2017 |
Chandel NS. Mitochondria: back to the future. Nature Reviews. Molecular Cell Biology. PMID 29259335 DOI: 10.1038/Nrm.2017.133 |
0.415 |
|
| 2017 |
Martínez-Reyes I, Chandel NS. Waste Not, Want Not: Lactate Oxidation Fuels the TCA Cycle. Cell Metabolism. 26: 803-804. PMID 29211977 DOI: 10.1016/J.Cmet.2017.11.005 |
0.344 |
|
| 2017 |
Sala MA, Chen C, Zhang Q, Do-Umehara HC, Wu W, Misharin AV, Waypa GB, Fang D, Budinger GRS, Liu S, Chandel NS, Schumacker PT, Sznajder JI, Liu J. JNK2 Upregulates Hypoxia-Inducible Factors and Contributes to Hypoxia-Induced Erythropoiesis and Pulmonary Hypertension. The Journal of Biological Chemistry. PMID 29118187 DOI: 10.1074/Jbc.Ra117.000440 |
0.374 |
|
| 2017 |
Gonzalez-Gonzalez FJ, Chandel N, Jain M, Budinger GRS. Reactive oxygen species as signaling molecules in the development of lung fibrosis. Translational Research : the Journal of Laboratory and Clinical Medicine. PMID 29080401 DOI: 10.1016/J.Trsl.2017.09.005 |
0.347 |
|
| 2017 |
Reczek CR, Birsoy K, Kong H, Martínez-Reyes I, Wang T, Gao P, Sabatini DM, Chandel NS. A CRISPR screen identifies a pathway required for paraquat-induced cell death. Nature Chemical Biology. PMID 29058724 DOI: 10.1038/Nchembio.2499 |
0.437 |
|
| 2017 |
Horn A, Van der Meulen JH, Defour A, Hogarth M, Sreetama SC, Reed A, Scheffer L, Chandel NS, Jaiswal JK. Mitochondrial redox signaling enables repair of injured skeletal muscle cells. Science Signaling. 10. PMID 28874604 DOI: 10.1126/Scisignal.Aaj1978 |
0.428 |
|
| 2017 |
Mehta MM, Weinberg SE, Chandel NS. Mitochondrial control of immunity: beyond ATP. Nature Reviews. Immunology. PMID 28669986 DOI: 10.1038/Nri.2017.66 |
0.422 |
|
| 2017 |
Calvert AE, Chalastanis A, Wu Y, Hurley LA, Kouri FM, Bi Y, Kachman M, May JL, Bartom E, Hua Y, Mishra RK, Schiltz GE, Dubrovskyi O, Mazar AP, Peter ME, ... ... Chandel NS, et al. Cancer-Associated IDH1 Promotes Growth and Resistance to Targeted Therapies in the Absence of Mutation. Cell Reports. 19: 1858-1873. PMID 28564604 DOI: 10.1016/J.Celrep.2017.05.014 |
0.374 |
|
| 2017 |
Liu X, Zhang Y, Ni M, Cao H, Signer RAJ, Li D, Li M, Gu Z, Hu Z, Dickerson KE, Weinberg SE, Chandel NS, DeBerardinis RJ, Zhou F, Shao Z, et al. Regulation of mitochondrial biogenesis in erythropoiesis by mTORC1-mediated protein translation. Nature Cell Biology. PMID 28504707 DOI: 10.1038/Ncb3527 |
0.458 |
|
| 2017 |
Ansó E, Weinberg SE, Diebold LP, Thompson BJ, Malinge S, Schumacker PT, Liu X, Zhang Y, Shao Z, Steadman M, Marsh KM, Xu J, Crispino JD, Chandel NS. The mitochondrial respiratory chain is essential for haematopoietic stem cell function. Nature Cell Biology. PMID 28504706 DOI: 10.1038/Ncb3529 |
0.38 |
|
| 2017 |
McElroy GS, Chandel NS. Mitochondria control acute and chronic responses to hypoxia. Experimental Cell Research. 356: 217-222. PMID 28327410 DOI: 10.1016/J.Yexcr.2017.03.034 |
0.442 |
|
| 2016 |
Dutta RK, Kondeti VK, Sharma I, Chandel NS, Quaggin SE, Kanwar YS. Beneficial Effects of Myo-Inositol Oxygenase Deficiency in Cisplatin-Induced AKI. Journal of the American Society of Nephrology : Jasn. PMID 27895157 DOI: 10.1681/Asn.2016070744 |
0.355 |
|
| 2016 |
Kim SJ, Cheresh P, Jablonski RP, Morales-Nebreda L, Cheng Y, Hogan E, Yeldandi A, Chi M, Piseaux R, Ridge K, Michael Hart C, Chandel N, Scott Budinger GR, Kamp DW. Mitochondrial catalase overexpressed transgenic mice are protected against lung fibrosis in part via preventing alveolar epithelial cell mitochondrial DNA damage. Free Radical Biology & Medicine. PMID 27840320 DOI: 10.1016/J.Freeradbiomed.2016.11.007 |
0.44 |
|
| 2016 |
Almassalha LM, Bauer GM, Chandler JE, Gladstein S, Cherkezyan L, Stypula-Cyrus Y, Weinberg S, Zhang D, Thusgaard Ruhoff P, Roy HK, Subramanian H, Chandel NS, Szleifer I, Backman V. Label-free imaging of the native, living cellular nanoarchitecture using partial-wave spectroscopic microscopy. Proceedings of the National Academy of Sciences of the United States of America. PMID 27702891 DOI: 10.1073/Pnas.1608198113 |
0.303 |
|
| 2016 |
Chandel NS, Jasper H, Ho TT, Passegué E. Metabolic regulation of stem cell function in tissue homeostasis and organismal ageing. Nature Cell Biology. PMID 27428307 DOI: 10.1038/Ncb3385 |
0.324 |
|
| 2016 |
DeBerardinis RJ, Chandel NS. Fundamentals of cancer metabolism. Science Advances. 2: e1600200. PMID 27386546 DOI: 10.1126/Sciadv.1600200 |
0.366 |
|
| 2016 |
Navarro P, Bueno MJ, Zagorac I, Mondejar T, Sanchez J, Mourón S, Muñoz J, Gómez-López G, Jimenez-Renard V, Mulero F, Chandel NS, Quintela-Fandino M. Targeting Tumor Mitochondrial Metabolism Overcomes Resistance to Antiangiogenics. Cell Reports. PMID 27292634 DOI: 10.1016/J.Celrep.2016.05.052 |
0.377 |
|
| 2016 |
Diebold L, Chandel NS. Mitochondrial ROS regulation of proliferating cells. Free Radical Biology & Medicine. PMID 27154978 DOI: 10.1016/J.Freeradbiomed.2016.04.198 |
0.466 |
|
| 2016 |
Hamanaka RB, Weinberg SE, Reczek CR, Chandel NS. The Mitochondrial Respiratory Chain Is Required for Organismal Adaptation to Hypoxia. Cell Reports. PMID 27068470 DOI: 10.1016/J.Celrep.2016.03.044 |
0.483 |
|
| 2016 |
Israeli E, Dryanovski DI, Schumacker PT, Chandel NS, Singer JD, Julien JP, Goldman RD, Opal P. Intermediate filament aggregates cause mitochondrial dysmotility and increase energy demands in Giant Axonal Neuropathy. Human Molecular Genetics. PMID 27000625 DOI: 10.1093/Hmg/Ddw081 |
0.367 |
|
| 2016 |
Diebold LP, Chandel NS. HSC Fate Is Tethered to Mitochondria. Cell Stem Cell. 18: 303-4. PMID 26942848 DOI: 10.1016/J.Stem.2016.02.007 |
0.351 |
|
| 2016 |
Liu X, Zhang Y, Ni M, Cao H, Signer R, Li D, Gu Z, Hu Z, Chandel N, DeBerardinis R, Zhou F, Shao Z, Xu J. Mitochondria Coordinate Intracellular Metabolism and Epigenetic Gene Regulation during Erythropoiesis Blood. 128: 1038-1038. DOI: 10.1182/Blood.V128.22.1038.1038 |
0.473 |
|
| 2015 |
Martínez-Reyes I, Diebold LP, Kong H, Schieber M, Huang H, Hensley CT, Mehta MM, Wang T, Santos JH, Woychik R, Dufour E, Spelbrink JN, Weinberg SE, Zhao Y, DeBerardinis RJ, ... Chandel NS, et al. TCA Cycle and Mitochondrial Membrane Potential Are Necessary for Diverse Biological Functions. Molecular Cell. PMID 26725009 DOI: 10.1016/J.Molcel.2015.12.002 |
0.819 |
|
| 2015 |
Zhang Q, Kuang H, Chen C, Yan J, Do-Umehara HC, Liu XY, Dada L, Ridge KM, Chandel NS, Liu J. Corrigendum: The kinase Jnk2 promotes stress-induced mitophagy by targeting the small mitochondrial form of the tumor suppressor ARF for degradation. Nature Immunology. 16: 785. PMID 26086147 DOI: 10.1038/Ni0715-785B |
0.387 |
|
| 2015 |
Chandel NS. Evolution of Mitochondria as Signaling Organelles. Cell Metabolism. 22: 204-6. PMID 26073494 DOI: 10.1016/J.Cmet.2015.05.013 |
0.373 |
|
| 2015 |
Zhang Q, Kuang H, Chen C, Yan J, Do-Umehara HC, Liu XY, Dada L, Ridge KM, Chandel NS, Liu J. The kinase Jnk2 promotes stress-induced mitophagy by targeting the small mitochondrial form of the tumor suppressor ARF for degradation. Nature Immunology. 16: 458-66. PMID 25799126 DOI: 10.1038/Ni.3130 |
0.424 |
|
| 2015 |
Weinberg SE, Sena LA, Chandel NS. Mitochondria in the regulation of innate and adaptive immunity. Immunity. 42: 406-17. PMID 25786173 DOI: 10.1016/J.Immuni.2015.02.002 |
0.772 |
|
| 2015 |
Weinberg SE, Chandel NS. Targeting mitochondria metabolism for cancer therapy. Nature Chemical Biology. 11: 9-15. PMID 25517383 DOI: 10.1038/Nchembio.1712 |
0.433 |
|
| 2015 |
Reczek CR, Chandel NS. ROS-dependent signal transduction. Current Opinion in Cell Biology. 33: 8-13. PMID 25305438 DOI: 10.1016/J.Ceb.2014.09.010 |
0.394 |
|
| 2015 |
Galluzzi L, Bravo-San Pedro JM, Vitale I, Aaronson SA, Abrams JM, Adam D, Alnemri ES, Altucci L, Andrews D, Annicchiarico-Petruzzelli M, Baehrecke EH, Bazan NG, Bertrand MJ, Bianchi K, Blagosklonny MV, ... ... Chandel NS, et al. Essential versus accessory aspects of cell death: recommendations of the NCCD 2015. Cell Death and Differentiation. 22: 58-73. PMID 25236395 DOI: 10.1038/Cdd.2014.137 |
0.422 |
|
| 2014 |
Sullivan LB, Chandel NS. Mitochondrial reactive oxygen species and cancer. Cancer & Metabolism. 2: 17. PMID 25671107 DOI: 10.1186/2049-3002-2-17 |
0.756 |
|
| 2014 |
Martínez-Reyes I, Chandel NS. Mitochondrial one-carbon metabolism maintains redox balance during hypoxia. Cancer Discovery. 4: 1371-3. PMID 25477105 DOI: 10.1158/2159-8290.Cd-14-1228 |
0.511 |
|
| 2014 |
Chandel N. Four key questions about metformin and cancer. Bmc Biology. 12: 85. PMID 25347776 DOI: 10.1186/S12915-014-0085-1 |
0.438 |
|
| 2014 |
Schieber M, Chandel NS. TOR signaling couples oxygen sensing to lifespan in C. elegans. Cell Reports. 9: 9-15. PMID 25284791 DOI: 10.1016/J.Celrep.2014.08.075 |
0.81 |
|
| 2014 |
Queisser MA, Dada LA, Deiss-Yehiely N, Angulo M, Zhou G, Kouri FM, Knab LM, Liu J, Stegh AH, DeCamp MM, Budinger GR, Chandel NS, Ciechanover A, Iwai K, Sznajder JI. HOIL-1L functions as the PKCζ ubiquitin ligase to promote lung tumor growth. American Journal of Respiratory and Critical Care Medicine. 190: 688-98. PMID 25118570 DOI: 10.1164/Rccm.201403-0463Oc |
0.303 |
|
| 2014 |
Glasauer A, Chandel NS. Targeting antioxidants for cancer therapy. Biochemical Pharmacology. 92: 90-101. PMID 25078786 DOI: 10.1016/J.Bcp.2014.07.017 |
0.818 |
|
| 2014 |
Weinberg SE, Chandel NS. Futility sustains memory T cells. Immunity. 41: 1-3. PMID 25035944 DOI: 10.1016/J.Immuni.2014.06.009 |
0.3 |
|
| 2014 |
Chandel NS, Tuveson DA. The promise and perils of antioxidants for cancer patients. The New England Journal of Medicine. 371: 177-8. PMID 25006725 DOI: 10.1056/Nejmcibr1405701 |
0.371 |
|
| 2014 |
Chandel NS. Mitochondria and cancer. Cancer & Metabolism. 2: 8. PMID 24917929 DOI: 10.1186/2049-3002-2-8 |
0.423 |
|
| 2014 |
Chandel NS. Mitochondria as signaling organelles. Bmc Biology. 12: 34. PMID 24884669 DOI: 10.1186/1741-7007-12-34 |
0.456 |
|
| 2014 |
Mullen AR, Hu Z, Shi X, Jiang L, Boroughs LK, Kovacs Z, Boriack R, Rakheja D, Sullivan LB, Linehan WM, Chandel NS, DeBerardinis RJ. Oxidation of alpha-ketoglutarate is required for reductive carboxylation in cancer cells with mitochondrial defects. Cell Reports. 7: 1679-90. PMID 24857658 DOI: 10.1016/J.Celrep.2014.04.037 |
0.754 |
|
| 2014 |
Schieber M, Chandel NS. ROS function in redox signaling and oxidative stress. Current Biology : Cb. 24: R453-62. PMID 24845678 DOI: 10.1016/J.Cub.2014.03.034 |
0.781 |
|
| 2014 |
Wheaton WW, Weinberg SE, Hamanaka RB, Soberanes S, Sullivan LB, Anso E, Glasauer A, Dufour E, Mutlu GM, Budigner GS, Chandel NS. Metformin inhibits mitochondrial complex I of cancer cells to reduce tumorigenesis. Elife. 3: e02242. PMID 24843020 DOI: 10.7554/Elife.02242 |
0.816 |
|
| 2014 |
Hadji A, Ceppi P, Murmann AE, Brockway S, Pattanayak A, Bhinder B, Hau A, De Chant S, Parimi V, Kolesza P, Richards J, Chandel N, Djaballah H, Peter ME. Death induced by CD95 or CD95 ligand elimination. Cell Reports. 7: 208-22. PMID 24656822 DOI: 10.1016/J.Celrep.2014.02.035 |
0.372 |
|
| 2014 |
Sullivan LB, Chandel NS. Mitochondrial metabolism in TCA cycle mutant cancer cells. Cell Cycle (Georgetown, Tex.). 13: 347-8. PMID 24335489 DOI: 10.4161/Cc.27513 |
0.789 |
|
| 2014 |
Glasauer A, Sena LA, Diebold LP, Mazar AP, Chandel NS. Targeting SOD1 reduces experimental non–small-cell lung cancer. The Journal of Clinical Investigation. 124: 117-28. PMID 24292713 DOI: 10.1172/Jci71714 |
0.794 |
|
| 2014 |
Wheaton WW, Weinberg SE, Hamanaka RB, Soberanes S, Sullivan LB, Anso E, Glasauer A, Dufour E, Mutlu GM, Budigner GS, Chandel NS. Author response: Metformin inhibits mitochondrial complex I of cancer cells to reduce tumorigenesis Elife. DOI: 10.7554/Elife.02242.019 |
0.811 |
|
| 2014 |
Chandel NS. Metformin, mitochondria and cancer Cancer & Metabolism. 2. DOI: 10.1186/2049-3002-2-S1-O27 |
0.486 |
|
| 2014 |
Passegue E, Teitell M, Ding S, Rando T, Belmonte JCI, Ramalho-Santos M, Terzic A, Brunet A, Chandel NS, Bonnet D, Jasper H. Stem cell energetics Cell Metabolism. 20: 922-925. DOI: 10.1016/J.Cmet.2014.11.007 |
0.411 |
|
| 2013 |
Hamanaka RB, Chandel NS. Mitochondrial metabolism as a regulator of keratinocyte differentiation. Cellular Logistics. 3: e25456. PMID 24475371 DOI: 10.4161/Cl.25456 |
0.484 |
|
| 2013 |
Anso E, Mullen AR, Felsher DW, Matés JM, Deberardinis RJ, Chandel NS. Metabolic changes in cancer cells upon suppression of MYC. Cancer & Metabolism. 1: 7. PMID 24280108 DOI: 10.1186/2049-3002-1-7 |
0.381 |
|
| 2013 |
Peek CB, Affinati AH, Ramsey KM, Kuo HY, Yu W, Sena LA, Ilkayeva O, Marcheva B, Kobayashi Y, Omura C, Levine DC, Bacsik DJ, Gius D, Newgard CB, Goetzman E, ... Chandel NS, et al. Circadian clock NAD+ cycle drives mitochondrial oxidative metabolism in mice. Science (New York, N.Y.). 342: 1243417. PMID 24051248 DOI: 10.1126/Science.1243417 |
0.764 |
|
| 2013 |
Patra KC, Wang Q, Bhaskar PT, Miller L, Wang Z, Wheaton W, Chandel N, Laakso M, Muller WJ, Allen EL, Jha AK, Smolen GA, Clasquin MF, Robey RB, Hay N. Hexokinase 2 is required for tumor initiation and maintenance and its systemic deletion is therapeutic in mouse models of cancer. Cancer Cell. 24: 213-28. PMID 23911236 DOI: 10.1016/J.Ccr.2013.06.014 |
0.326 |
|
| 2013 |
Herrera I, Cisneros J, Maldonado M, Ramírez R, Ortiz-Quintero B, Anso E, Chandel NS, Selman M, Pardo A. Matrix metalloproteinase (MMP)-1 induces lung alveolar epithelial cell migration and proliferation, protects from apoptosis, and represses mitochondrial oxygen consumption. The Journal of Biological Chemistry. 288: 25964-75. PMID 23902766 DOI: 10.1074/Jbc.M113.459784 |
0.413 |
|
| 2013 |
Kamp DW, Liu G, Cheresh P, Kim SJ, Mueller A, Lam AP, Trejo H, Williams D, Tulasiram S, Baker M, Ridge K, Chandel NS, Beri R. Asbestos-induced alveolar epithelial cell apoptosis: The role of endoplasmic reticulum stress response American Journal of Respiratory Cell and Molecular Biology. 49: 892-901. PMID 23885834 DOI: 10.1165/Rcmb.2013-0053Oc |
0.367 |
|
| 2013 |
Chandel NS, Budinger GR. The good and the bad of antibiotics. Science Translational Medicine. 5: 192fs25. PMID 23825300 DOI: 10.1126/Scitranslmed.3006567 |
0.419 |
|
| 2013 |
Sullivan LB, Martinez-Garcia E, Nguyen H, Mullen AR, Dufour E, Sudarshan S, Licht JD, Deberardinis RJ, Chandel NS. The proto-oncometabolite fumarate binds glutathione to amplify ROS-dependent signaling. Molecular Cell. 51: 236-48. PMID 23747014 DOI: 10.1016/J.Molcel.2013.05.003 |
0.761 |
|
| 2013 |
Schieber MS, Chandel NS. ROS links glucose metabolism to breast cancer stem cell and EMT phenotype. Cancer Cell. 23: 265-7. PMID 23518342 DOI: 10.1016/J.Ccr.2013.02.021 |
0.776 |
|
| 2013 |
Sena LA, Li S, Jairaman A, Prakriya M, Ezponda T, Hildeman DA, Wang CR, Schumacker PT, Licht JD, Perlman H, Bryce PJ, Chandel NS. Mitochondria are required for antigen-specific T cell activation through reactive oxygen species signaling. Immunity. 38: 225-36. PMID 23415911 DOI: 10.1016/J.Immuni.2012.10.020 |
0.772 |
|
| 2013 |
Glasauer A, Chandel NS. ROS. Current Biology : Cb. 23: R100-2. PMID 23391379 DOI: 10.1016/j.cub.2012.12.011 |
0.814 |
|
| 2013 |
Hamanaka RB, Glasauer A, Hoover P, Yang S, Blatt H, Mullen AR, Getsios S, Gottardi CJ, DeBerardinis RJ, Lavker RM, Chandel NS. Mitochondrial reactive oxygen species promote epidermal differentiation and hair follicle development. Science Signaling. 6: ra8. PMID 23386745 DOI: 10.1126/Scisignal.2003638 |
0.822 |
|
| 2013 |
Jain M, Rivera S, Monclus EA, Synenki L, Zirk A, Eisenbart J, Feghali-Bostwick C, Mutlu GM, Budinger GR, Chandel NS. Mitochondrial reactive oxygen species regulate transforming growth factor-β signaling. The Journal of Biological Chemistry. 288: 770-7. PMID 23204521 DOI: 10.1074/Jbc.M112.431973 |
0.406 |
|
| 2013 |
Snyder CM, Shroff EH, Liu J, Chandel NS. The individual loss of the BH3-only proteins BID, BIM, PUMA, BAD and NOXA does not protect against nitric oxide-induced cell death. Plos One. DOI: 10.1371/Journal.Pone.0007059.G004 |
0.803 |
|
| 2012 |
Sena LA, Chandel NS. Physiological roles of mitochondrial reactive oxygen species. Molecular Cell. 48: 158-67. PMID 23102266 DOI: 10.1016/J.Molcel.2012.09.025 |
0.784 |
|
| 2012 |
Sullivan LB, Santos JH, Chandel NS. Mitochondria and telomeres: the promiscuous roles of TIN2. Molecular Cell. 47: 823-4. PMID 23020852 DOI: 10.1016/J.Molcel.2012.09.006 |
0.695 |
|
| 2012 |
Peng H, Kaplan N, Hamanaka RB, Katsnelson J, Blatt H, Yang W, Hao L, Bryar PJ, Johnson RS, Getsios S, Chandel NS, Lavker RM. microRNA-31/factor-inhibiting hypoxia-inducible factor 1 nexus regulates keratinocyte differentiation. Proceedings of the National Academy of Sciences of the United States of America. 109: 14030-4. PMID 22891326 DOI: 10.1073/Pnas.1111292109 |
0.321 |
|
| 2012 |
Jeon SM, Chandel NS, Hay N. AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress. Nature. 485: 661-5. PMID 22660331 DOI: 10.1038/Nature11066 |
0.423 |
|
| 2012 |
Soberanes S, Gonzalez A, Urich D, Chiarella SE, Radigan KA, Osornio-Vargas A, Joseph J, Kalyanaraman B, Ridge KM, Chandel NS, Mutlu GM, De Vizcaya-Ruiz A, Budinger GR. Particulate matter Air Pollution induces hypermethylation of the p16 promoter Via a mitochondrial ROS-JNK-DNMT1 pathway. Scientific Reports. 2: 275. PMID 22355787 DOI: 10.1038/Srep00275 |
0.37 |
|
| 2012 |
Hamanaka RB, Chandel NS. Targeting glucose metabolism for cancer therapy. The Journal of Experimental Medicine. 209: 211-5. PMID 22330683 DOI: 10.1084/Jem.20120162 |
0.345 |
|
| 2012 |
Mullen AR, Wheaton WW, Jin ES, Chen PH, Sullivan LB, Cheng T, Yang Y, Linehan WM, Chandel NS, DeBerardinis RJ. Reductive carboxylation supports growth in tumour cells with defective mitochondria. Nature. 481: 385-8. PMID 22101431 DOI: 10.1038/Nature10642 |
0.746 |
|
| 2012 |
Woo DK, Green PD, Santos JH, D'Souza AD, Walther Z, Martin WD, Christian BE, Chandel NS, Shadel GS. Mitochondrial genome instability and ROS enhance intestinal tumorigenesis in APC(Min/+) mice. The American Journal of Pathology. 180: 24-31. PMID 22056359 DOI: 10.1016/J.Ajpath.2011.10.003 |
0.486 |
|
| 2012 |
Mauro C, Leow SC, Anso E, Rocha S, Thotakura AK, Tornatore L, Moretti M, De Smaele E, Beg AA, Tergaonkar V, Chandel NS, Franzoso G. The Control of Cell Energy Metabolism by NF-Kb Transcription Factors Transplantation Journal. 94: 493. DOI: 10.1097/00007890-201211271-00943 |
0.307 |
|
| 2011 |
Shimi T, Butin-Israeli V, Adam SA, Hamanaka RB, Goldman AE, Lucas CA, Shumaker DK, Kosak ST, Chandel NS, Goldman RD. The role of nuclear lamin B1 in cell proliferation and senescence. Genes & Development. 25: 2579-93. PMID 22155925 DOI: 10.1101/Gad.179515.111 |
0.487 |
|
| 2011 |
Tormos KV, Chandel NS. Seeing the light: probing ROS in vivo using redox GFP. Cell Metabolism. 14: 720-1. PMID 22152299 DOI: 10.1016/J.Cmet.2011.11.008 |
0.789 |
|
| 2011 |
Hamanaka RB, Chandel NS. Cell biology. Warburg effect and redox balance. Science (New York, N.Y.). 334: 1219-20. PMID 22144609 DOI: 10.1126/Science.1215637 |
0.474 |
|
| 2011 |
Tormos KV, Anso E, Hamanaka RB, Eisenbart J, Joseph J, Kalyanaraman B, Chandel NS. Mitochondrial complex III ROS regulate adipocyte differentiation. Cell Metabolism. 14: 537-44. PMID 21982713 DOI: 10.1016/J.Cmet.2011.08.007 |
0.825 |
|
| 2011 |
Mauro C, Leow SC, Anso E, Rocha S, Thotakura AK, Tornatore L, Moretti M, De Smaele E, Beg AA, Tergaonkar V, Chandel NS, Franzoso G. NF-κB controls energy homeostasis and metabolic adaptation by upregulating mitochondrial respiration. Nature Cell Biology. 13: 1272-9. PMID 21968997 DOI: 10.1038/Ncb2324 |
0.413 |
|
| 2011 |
Vohwinkel CU, Lecuona E, Sun H, Sommer N, Vadász I, Chandel NS, Sznajder JI. Elevated CO(2) levels cause mitochondrial dysfunction and impair cell proliferation. The Journal of Biological Chemistry. 286: 37067-76. PMID 21903582 DOI: 10.1074/Jbc.M111.290056 |
0.406 |
|
| 2011 |
Gusarova GA, Trejo HE, Dada LA, Briva A, Welch LC, Hamanaka RB, Mutlu GM, Chandel NS, Prakriya M, Sznajder JI. Hypoxia leads to Na,K-ATPase downregulation via Ca(2+) release-activated Ca(2+) channels and AMPK activation. Molecular and Cellular Biology. 31: 3546-56. PMID 21730292 DOI: 10.1128/Mcb.05114-11 |
0.32 |
|
| 2011 |
Dirisina R, Katzman RB, Goretsky T, Managlia E, Mittal N, Williams DB, Qiu W, Yu J, Chandel NS, Zhang L, Barrett TA. p53 and PUMA independently regulate apoptosis of intestinal epithelial cells in patients and mice with colitis. Gastroenterology. 141: 1036-45. PMID 21699775 DOI: 10.1053/J.Gastro.2011.05.032 |
0.366 |
|
| 2011 |
Loor G, Kondapalli J, Iwase H, Chandel NS, Waypa GB, Guzy RD, Vanden Hoek TL, Schumacker PT. Mitochondrial oxidant stress triggers cell death in simulated ischemia-reperfusion. Biochimica Et Biophysica Acta. 1813: 1382-94. PMID 21185334 DOI: 10.1016/J.Bbamcr.2010.12.008 |
0.495 |
|
| 2011 |
Wheaton WW, Chandel NS. Hypoxia. 2. Hypoxia regulates cellular metabolism. American Journal of Physiology. Cell Physiology. 300: C385-93. PMID 21123733 DOI: 10.1152/Ajpcell.00485.2010 |
0.429 |
|
| 2011 |
Budinger GR, Mutlu GM, Urich D, Soberanes S, Buccellato LJ, Hawkins K, Chiarella SE, Radigan KA, Eisenbart J, Agrawal H, Berkelhamer S, Hekimi S, Zhang J, Perlman H, Schumacker PT, ... ... Chandel NS, et al. Epithelial cell death is an important contributor to oxidant-mediated acute lung injury. American Journal of Respiratory and Critical Care Medicine. 183: 1043-54. PMID 20959557 DOI: 10.1164/Rccm.201002-0181Oc |
0.323 |
|
| 2010 |
Loor G, Kondapalli J, Schriewer JM, Chandel NS, Vanden Hoek TL, Schumacker PT. Menadione triggers cell death through ROS-dependent mechanisms involving PARP activation without requiring apoptosis. Free Radical Biology & Medicine. 49: 1925-36. PMID 20937380 DOI: 10.1016/J.Freeradbiomed.2010.09.021 |
0.528 |
|
| 2010 |
Chandel NS. Mitochondrial complex III: an essential component of universal oxygen sensing machinery? Respiratory Physiology & Neurobiology. 174: 175-81. PMID 20708106 DOI: 10.1016/J.Resp.2010.08.004 |
0.436 |
|
| 2010 |
Hamanaka RB, Chandel NS. Mitochondrial reactive oxygen species regulate cellular signaling and dictate biological outcomes. Trends in Biochemical Sciences. 35: 505-13. PMID 20430626 DOI: 10.1016/J.Tibs.2010.04.002 |
0.46 |
|
| 2010 |
Weinberg F, Hamanaka R, Wheaton WW, Weinberg S, Joseph J, Lopez M, Kalyanaraman B, Mutlu GM, Budinger GR, Chandel NS. Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity. Proceedings of the National Academy of Sciences of the United States of America. 107: 8788-93. PMID 20421486 DOI: 10.1073/Pnas.1003428107 |
0.799 |
|
| 2010 |
Chandel NS. Mitochondrial regulation of oxygen sensing. Advances in Experimental Medicine and Biology. 661: 339-54. PMID 20204741 DOI: 10.1007/978-1-60761-500-2_22 |
0.508 |
|
| 2010 |
Tormos KV, Chandel NS. Inter-connection between mitochondria and HIFs. Journal of Cellular and Molecular Medicine. 14: 795-804. PMID 20158574 DOI: 10.1111/J.1582-4934.2010.01031.X |
0.829 |
|
| 2010 |
Na N, Chandel NS, Litvan J, Ridge KM. Mitochondrial reactive oxygen species are required for hypoxia-induced degradation of keratin intermediate filaments. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 799-809. PMID 19897662 DOI: 10.1096/Fj.08-128967 |
0.499 |
|
| 2009 |
Weinberg F, Chandel NS. Mitochondrial metabolism and cancer. Annals of the New York Academy of Sciences. 1177: 66-73. PMID 19845608 DOI: 10.1111/J.1749-6632.2009.05039.X |
0.755 |
|
| 2009 |
Hamanaka RB, Chandel NS. Mitochondrial reactive oxygen species regulate hypoxic signaling. Current Opinion in Cell Biology. 21: 894-9. PMID 19781926 DOI: 10.1016/J.Ceb.2009.08.005 |
0.486 |
|
| 2009 |
Snyder CM, Shroff EH, Liu J, Chandel NS. Nitric oxide induces cell death by regulating anti-apoptotic BCL-2 family members. Plos One. 4: e7059. PMID 19768117 DOI: 10.1371/Journal.Pone.0007059 |
0.832 |
|
| 2009 |
Weinberg F, Chandel NS. Reactive oxygen species-dependent signaling regulates cancer. Cellular and Molecular Life Sciences : Cmls. 66: 3663-73. PMID 19629388 DOI: 10.1007/S00018-009-0099-Y |
0.747 |
|
| 2009 |
Snyder CM, Chandel NS. Mitochondrial regulation of cell survival and death during low-oxygen conditions. Antioxidants & Redox Signaling. 11: 2673-83. PMID 19580395 DOI: 10.1089/Ars.2009.2730 |
0.783 |
|
| 2009 |
Shroff EH, Snyder CM, Budinger GR, Jain M, Chew TL, Khuon S, Perlman H, Chandel NS. BH3 peptides induce mitochondrial fission and cell death independent of BAX/BAK. Plos One. 4: e5646. PMID 19468307 DOI: 10.1371/Journal.Pone.0005646 |
0.819 |
|
| 2009 |
Gusarova GA, Dada LA, Kelly AM, Brodie C, Witters LA, Chandel NS, Sznajder JI. Alpha1-AMP-activated protein kinase regulates hypoxia-induced Na,K-ATPase endocytosis via direct phosphorylation of protein kinase C zeta. Molecular and Cellular Biology. 29: 3455-64. PMID 19380482 DOI: 10.1128/Mcb.00054-09 |
0.382 |
|
| 2009 |
Emerling BM, Weinberg F, Snyder C, Burgess Z, Mutlu GM, Viollet B, Budinger GR, Chandel NS. Hypoxic activation of AMPK is dependent on mitochondrial ROS but independent of an increase in AMP/ATP ratio. Free Radical Biology & Medicine. 46: 1386-91. PMID 19268526 DOI: 10.1016/J.Freeradbiomed.2009.02.019 |
0.815 |
|
| 2009 |
Urich D, Soberanes S, Burgess Z, Chiarella SE, Ghio AJ, Ridge KM, Kamp DW, Chandel NS, Mutlu GM, Budinger GRS. Proapoptotic Noxa is required for particulate matterinduced cell death and lung inflammation Faseb Journal. 23: 2055-2064. PMID 19237507 DOI: 10.1096/Fj.08-114546 |
0.391 |
|
| 2009 |
Soberanes S, Urich D, Baker CM, Burgess Z, Chiarella SE, Bell EL, Ghio AJ, De Vizcaya-Ruiz A, Liu J, Ridge KM, Kamp DW, Chandel NS, Schumacker PT, Mutlu GM, Budinger GR. Mitochondrial complex III-generated oxidants activate ASK1 and JNK to induce alveolar epithelial cell death following exposure to particulate matter air pollution. The Journal of Biological Chemistry. 284: 2176-86. PMID 19033436 DOI: 10.1074/Jbc.M808844200 |
0.515 |
|
| 2009 |
Klimova TA, Bell EL, Shroff EH, Weinberg FD, Snyder CM, Dimri GP, Schumacker PT, Budinger GR, Chandel NS. Hyperoxia-induced premature senescence requires p53 and pRb, but not mitochondrial matrix ROS. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 783-94. PMID 18948382 DOI: 10.1096/Fj.08-114256 |
0.808 |
|
| 2008 |
Chandel NS, Simon MC. Hypoxia-inducible factor: roles in development, physiology, and disease. Cell Death and Differentiation. 15: 619-20. PMID 18345017 DOI: 10.1038/Cdd.2008.11 |
0.317 |
|
| 2008 |
Emerling BM, Weinberg F, Liu JL, Mak TW, Chandel NS. PTEN regulates p300-dependent hypoxia-inducible factor 1 transcriptional activity through Forkhead transcription factor 3a (FOXO3a). Proceedings of the National Academy of Sciences of the United States of America. 105: 2622-7. PMID 18268343 DOI: 10.1073/Pnas.0706790105 |
0.799 |
|
| 2008 |
Klimova T, Chandel NS. Mitochondrial complex III regulates hypoxic activation of HIF. Cell Death and Differentiation. 15: 660-6. PMID 18219320 DOI: 10.1038/Sj.Cdd.4402307 |
0.791 |
|
| 2008 |
Vadász I, Dada LA, Briva A, Trejo HE, Welch LC, Chen J, Tóth PT, Lecuona E, Witters LA, Schumacker PT, Chandel NS, Seeger W, Sznajder JI. AMP-activated protein kinase regulates CO2-induced alveolar epithelial dysfunction in rats and human cells by promoting Na,K-ATPase endocytosis. The Journal of Clinical Investigation. 118: 752-62. PMID 18188452 DOI: 10.1172/Jci29723 |
0.335 |
|
| 2008 |
Lin X, David CA, Donnelly JB, Michaelides M, Chandel NS, Huang X, Warrior U, Weinberg F, Tormos KV, Fesik SW, Shen Y. A chemical genomics screen highlights the essential role of mitochondria in HIF-1 regulation. Proceedings of the National Academy of Sciences of the United States of America. 105: 174-9. PMID 18172210 DOI: 10.1073/Pnas.0706585104 |
0.803 |
|
| 2008 |
Bell EL, Klimova T, Chandel NS. Targeting the mitochondria for cancer therapy: regulation of hypoxia-inducible factor by mitochondria. Antioxidants & Redox Signaling. 10: 635-40. PMID 17999628 DOI: 10.1089/Ars.2007.1655 |
0.763 |
|
| 2008 |
Guzy RD, Sharma B, Bell E, Chandel NS, Schumacker PT. Loss of the SdhB, but Not the SdhA, subunit of complex II triggers reactive oxygen species-dependent hypoxia-inducible factor activation and tumorigenesis. Molecular and Cellular Biology. 28: 718-31. PMID 17967865 DOI: 10.1128/Mcb.01338-07 |
0.411 |
|
| 2007 |
Emerling BM, Viollet B, Tormos KV, Chandel NS. Compound C inhibits hypoxic activation of HIF-1 independent of AMPK. Febs Letters. 581: 5727-31. PMID 18036344 DOI: 10.1016/J.Febslet.2007.11.038 |
0.803 |
|
| 2007 |
Bell EL, Chandel NS. Genetics of mitochondrial electron transport chain in regulating oxygen sensing. Methods in Enzymology. 435: 447-61. PMID 17998068 DOI: 10.1016/S0076-6879(07)35023-4 |
0.429 |
|
| 2007 |
Bell EL, Chandel NS. Mitochondrial oxygen sensing: regulation of hypoxia-inducible factor by mitochondrial generated reactive oxygen species. Essays in Biochemistry. 43: 17-27. PMID 17705790 DOI: 10.1042/Bse0430017 |
0.505 |
|
| 2007 |
Wang HL, Akinci IO, Baker CM, Urich D, Bellmeyer A, Jain M, Chandel NS, Mutlu GM, Budinger GR. The intrinsic apoptotic pathway is required for lipopolysaccharide-induced lung endothelial cell death. Journal of Immunology (Baltimore, Md. : 1950). 179: 1834-41. PMID 17641050 DOI: 10.4049/Jimmunol.179.3.1834 |
0.437 |
|
| 2007 |
Iwase H, Robin E, Guzy RD, Mungai PT, Vanden Hoek TL, Chandel NS, Levraut J, Schumacker PT. Nitric oxide during ischemia attenuates oxidant stress and cell death during ischemia and reperfusion in cardiomyocytes. Free Radical Biology & Medicine. 43: 590-9. PMID 17640569 DOI: 10.1016/J.Freeradbiomed.2007.05.017 |
0.413 |
|
| 2007 |
Shroff EH, Snyder C, Chandel NS. Bcl-2 family members regulate anoxia-induced cell death. Antioxidants & Redox Signaling. 9: 1405-9. PMID 17627475 DOI: 10.1089/Ars.2007.1731 |
0.816 |
|
| 2007 |
Bell EL, Klimova TA, Eisenbart J, Schumacker PT, Chandel NS. Mitochondrial reactive oxygen species trigger hypoxia-inducible factor-dependent extension of the replicative life span during hypoxia. Molecular and Cellular Biology. 27: 5737-45. PMID 17562866 DOI: 10.1128/Mcb.02265-06 |
0.774 |
|
| 2007 |
Bell EL, Klimova TA, Eisenbart J, Moraes CT, Murphy MP, Budinger GR, Chandel NS. The Qo site of the mitochondrial complex III is required for the transduction of hypoxic signaling via reactive oxygen species production. The Journal of Cell Biology. 177: 1029-36. PMID 17562787 DOI: 10.1083/Jcb.200609074 |
0.733 |
|
| 2007 |
Shroff EH, Snyder C, Chandel NS. Role of Bcl-2 family members in anoxia induced cell death. Cell Cycle (Georgetown, Tex.). 6: 807-9. PMID 17377500 DOI: 10.4161/Cc.6.7.4044 |
0.825 |
|
| 2007 |
Subramanian RM, Chandel N, Budinger GR, Schumacker PT. Hypoxic conformance of metabolism in primary rat hepatocytes: a model of hepatic hibernation. Hepatology (Baltimore, Md.). 45: 455-64. PMID 17366663 DOI: 10.1002/Hep.21462 |
0.453 |
|
| 2007 |
Chandel NS, Budinger GR. The cellular basis for diverse responses to oxygen. Free Radical Biology & Medicine. 42: 165-74. PMID 17189822 DOI: 10.1016/J.Freeradbiomed.2006.10.048 |
0.533 |
|
| 2007 |
Brunelle JK, Shroff EH, Perlman H, Strasser A, Moraes CT, Flavell RA, Danial NN, Keith B, Thompson CB, Chandel NS. Loss of Mcl-1 protein and inhibition of electron transport chain together induce anoxic cell death. Molecular and Cellular Biology. 27: 1222-35. PMID 17145774 DOI: 10.1128/Mcb.01535-06 |
0.826 |
|
| 2006 |
Comellas AP, Dada LA, Lecuona E, Pesce LM, Chandel NS, Quesada N, Budinger GR, Strous GJ, Ciechanover A, Sznajder JI. Hypoxia-mediated degradation of Na,K-ATPase via mitochondrial reactive oxygen species and the ubiquitin-conjugating system. Circulation Research. 98: 1314-22. PMID 16614303 DOI: 10.1161/01.Res.0000222418.99976.1D |
0.381 |
|
| 2006 |
Mutlu GM, Snyder C, Bellmeyer A, Wang H, Hawkins K, Soberanes S, Welch LC, Ghio AJ, Chandel NS, Kamp D, Sznajder JI, Budinger GR. Airborne particulate matter inhibits alveolar fluid reabsorption in mice via oxidant generation. American Journal of Respiratory Cell and Molecular Biology. 34: 670-6. PMID 16439801 DOI: 10.1165/Rcmb.2005-0329Oc |
0.661 |
|
| 2006 |
Panduri V, Surapureddi S, Soberanes S, Weitzman SA, Chandel N, Kamp DW. P53 mediates amosite asbestos-induced alveolar epithelial cell mitochondria-regulated apoptosis. American Journal of Respiratory Cell and Molecular Biology. 34: 443-52. PMID 16357363 DOI: 10.1165/Rcmb.2005-0352Oc |
0.511 |
|
| 2005 |
Lewis JS, Meeke K, Osipo C, Ross EA, Kidawi N, Li T, Bell E, Chandel NS, Jordan VC. Intrinsic mechanism of estradiol-induced apoptosis in breast cancer cells resistant to estrogen deprivation. Journal of the National Cancer Institute. 97: 1746-59. PMID 16333030 DOI: 10.1093/Jnci/Dji400 |
0.354 |
|
| 2005 |
Lee VY, Schroedl C, Brunelle JK, Buccellato LJ, Akinci OI, Kaneto H, Snyder C, Eisenbart J, Budinger GR, Chandel NS. Bleomycin induces alveolar epithelial cell death through JNK-dependent activation of the mitochondrial death pathway. American Journal of Physiology. Lung Cellular and Molecular Physiology. 289: L521-8. PMID 16148050 DOI: 10.1152/Ajplung.00340.2004 |
0.814 |
|
| 2005 |
Bell EL, Emerling BM, Chandel NS. Mitochondrial regulation of oxygen sensing. Mitochondrion. 5: 322-32. PMID 16146708 DOI: 10.1016/J.Mito.2005.06.005 |
0.74 |
|
| 2005 |
Brunelle JK, Bell EL, Quesada NM, Vercauteren K, Tiranti V, Zeviani M, Scarpulla RC, Chandel NS. Oxygen sensing requires mitochondrial ROS but not oxidative phosphorylation. Cell Metabolism. 1: 409-14. PMID 16054090 DOI: 10.1016/J.Cmet.2005.05.002 |
0.828 |
|
| 2005 |
Emerling BM, Chandel NS. Oxygen sensing: getting pumped by sterols. Science's Stke : Signal Transduction Knowledge Environment. 2005: pe30. PMID 15972699 DOI: 10.1126/Stke.2892005Pe30 |
0.724 |
|
| 2005 |
Emerling BM, Platanias LC, Black E, Nebreda AR, Davis RJ, Chandel NS. Mitochondrial reactive oxygen species activation of p38 mitogen-activated protein kinase is required for hypoxia signaling. Molecular and Cellular Biology. 25: 4853-62. PMID 15923604 DOI: 10.1128/Mcb.25.12.4853-4862.2005 |
0.772 |
|
| 2004 |
Majewski N, Nogueira V, Bhaskar P, Coy PE, Skeen JE, Gottlob K, Chandel NS, Thompson CB, Robey RB, Hay N. Hexokinase-mitochondria interaction mediated by Akt is required to inhibit apoptosis in the presence or absence of Bax and Bak. Molecular Cell. 16: 819-30. PMID 15574336 DOI: 10.1016/J.Molcel.2004.11.014 |
0.462 |
|
| 2004 |
Alam H, Maizels ET, Park Y, Ghaey S, Feiger ZJ, Chandel NS, Hunzicker-Dunn M. Follicle-stimulating hormone activation of hypoxia-inducible factor-1 by the phosphatidylinositol 3-kinase/AKT/Ras homolog enriched in brain (Rheb)/mammalian target of rapamycin (mTOR) pathway is necessary for induction of select protein markers of follicular differentiation. The Journal of Biological Chemistry. 279: 19431-40. PMID 14982927 DOI: 10.1074/Jbc.M401235200 |
0.349 |
|
| 2004 |
DeHahn KC, Gonzales M, Gonzalez AM, Hopkinson SB, Chandel NS, Brunelle JK, Jones JC. The alpha4 laminin subunit regulates endothelial cell survival. Experimental Cell Research. 294: 281-9. PMID 14980521 DOI: 10.1016/J.Yexcr.2003.11.006 |
0.799 |
|
| 2004 |
Panduri V, Weitzman SA, Chandel NS, Kamp DW. Mitochondrial-derived free radicals mediate asbestos-induced alveolar epithelial cell apoptosis. American Journal of Physiology. Lung Cellular and Molecular Physiology. 286: L1220-7. PMID 14766669 DOI: 10.1152/Ajplung.00371.2003 |
0.519 |
|
| 2004 |
Brunelle JK, Santore MT, Budinger GR, Tang Y, Barrett TA, Zong WX, Kandel E, Keith B, Simon MC, Thompson CB, Hay N, Chandel NS. c-Myc sensitization to oxygen deprivation-induced cell death is dependent on Bax/Bak, but is independent of p53 and hypoxia-inducible factor-1. The Journal of Biological Chemistry. 279: 4305-12. PMID 14627695 DOI: 10.1074/Jbc.M312241200 |
0.828 |
|
| 2004 |
Buccellato LJ, Tso M, Akinci OI, Chandel NS, Budinger GR. Reactive oxygen species are required for hyperoxia-induced Bax activation and cell death in alveolar epithelial cells. The Journal of Biological Chemistry. 279: 6753-60. PMID 14625274 DOI: 10.1074/Jbc.M310145200 |
0.511 |
|
| 2003 |
Hanford HA, Wong CA, Kassan H, Cundiff DL, Chandel N, Underwood S, Mitchell CA, Soff GA. Angiostatin(4.5)-mediated apoptosis of vascular endothelial cells. Cancer Research. 63: 4275-80. PMID 12874037 |
0.303 |
|
| 2003 |
Dada LA, Chandel NS, Ridge KM, Pedemonte C, Bertorello AM, Sznajder JI. Hypoxia-induced endocytosis, of Na,K-ATPase in alveolar epithelial cells is mediated by mitochondrial reactive oxygen species and PKC-ζ Journal of Clinical Investigation. 111: 1057-1064. PMID 12671055 DOI: 10.1172/Jci16826 |
0.379 |
|
| 2003 |
Panduri V, Weitzman SA, Chandel N, Kamp DW. The mitochondria-regulated death pathway mediates asbestos-induced alveolar epithelial cell apoptosis. American Journal of Respiratory Cell and Molecular Biology. 28: 241-8. PMID 12540492 DOI: 10.1165/Rcmb.4903 |
0.499 |
|
| 2002 |
Schroedl C, McClintock DS, Budinger GR, Chandel NS. Hypoxic but not anoxic stabilization of HIF-1alpha requires mitochondrial reactive oxygen species. American Journal of Physiology. Lung Cellular and Molecular Physiology. 283: L922-31. PMID 12376345 DOI: 10.1152/Ajplung.00014.2002 |
0.394 |
|
| 2002 |
Brunelle JK, Chandel NS. Oxygen deprivation induced cell death: an update. Apoptosis : An International Journal On Programmed Cell Death. 7: 475-82. PMID 12370489 DOI: 10.1023/A:1020668923852 |
0.825 |
|
| 2002 |
Kamp DW, Panduri Va, Weitzman SA, Chandel N. Asbestos-induced alveolar epithelial cell apoptosis: role of mitochondrial dysfunction caused by iron-derived free radicals. Molecular and Cellular Biochemistry. 234: 153-60. PMID 12162428 |
0.363 |
|
| 2002 |
Chandel NS. Detection of oxygen-sensing properties of mitochondria. Methods in Enzymology. 352: 31-40. PMID 12125358 DOI: 10.1016/S0076-6879(02)52004-8 |
0.483 |
|
| 2002 |
Kulisz A, Chen N, Chandel NS, Shao Z, Schumacker PT. Mitochondrial ROS initiate phosphorylation of p38 MAP kinase during hypoxia in cardiomyocytes. American Journal of Physiology. Lung Cellular and Molecular Physiology. 282: L1324-9. PMID 12003789 DOI: 10.1152/Ajplung.00326.2001 |
0.456 |
|
| 2002 |
Santore MT, McClintock DS, Lee VY, Budinger GR, Chandel NS. Anoxia-induced apoptosis occurs through a mitochondria-dependent pathway in lung epithelial cells. American Journal of Physiology. Lung Cellular and Molecular Physiology. 282: L727-34. PMID 11880298 DOI: 10.1152/Ajplung.00281.2001 |
0.472 |
|
| 2002 |
Budinger GR, Tso M, McClintock DS, Dean DA, Sznajder JI, Chandel NS. Hyperoxia-induced apoptosis does not require mitochondrial reactive oxygen species and is regulated by Bcl-2 proteins. The Journal of Biological Chemistry. 277: 15654-60. PMID 11877388 DOI: 10.1074/Jbc.M109317200 |
0.511 |
|
| 2002 |
Lee VY, McClintock DS, Santore MT, Budinger GR, Chandel NS. Hypoxia sensitizes cells to nitric oxide-induced apoptosis. The Journal of Biological Chemistry. 277: 16067-74. PMID 11861645 DOI: 10.1074/Jbc.M111177200 |
0.504 |
|
| 2002 |
McClintock DS, Santore MT, Lee VY, Brunelle J, Budinger GR, Zong WX, Thompson CB, Hay N, Chandel NS. Bcl-2 family members and functional electron transport chain regulate oxygen deprivation-induced cell death. Molecular and Cellular Biology. 22: 94-104. PMID 11739725 DOI: 10.1128/Mcb.22.1.94-104.2002 |
0.843 |
|
| 2001 |
Chandel NS, Schumacker PT, Arch RH. Reactive oxygen species are downstream products of TRAF-mediated signal transduction. The Journal of Biological Chemistry. 276: 42728-36. PMID 11559697 DOI: 10.1074/Jbc.M103074200 |
0.392 |
|
| 2001 |
Waypa GB, Chandel NS, Schumacker PT. Model for hypoxic pulmonary vasoconstriction involving mitochondrial oxygen sensing. Circulation Research. 88: 1259-66. PMID 11420302 DOI: 10.1161/Hh1201.091960 |
0.372 |
|
| 2000 |
Chandel NS, Sznajder JI. Stretching the lung and programmed cell death. American Journal of Physiology. Lung Cellular and Molecular Physiology. 279: L1003-4. PMID 11076790 DOI: 10.1152/Ajplung.2000.279.6.L1003 |
0.305 |
|
| 2000 |
Chandel NS, Vander Heiden MG, Thompson CB, Schumacker PT. Redox regulation of p53 during hypoxia Oncogene. 19: 3840-3848. PMID 10951577 DOI: 10.1038/Sj.Onc.1203727 |
0.497 |
|
| 2000 |
Chandel NS, Trzyna WC, McClintock DS, Schumacker PT. Role of oxidants in NF-kappa B activation and TNF-alpha gene transcription induced by hypoxia and endotoxin. Journal of Immunology (Baltimore, Md. : 1950). 165: 1013-21. PMID 10878378 DOI: 10.4049/Jimmunol.165.2.1013 |
0.329 |
|
| 2000 |
Chandel NS, McClintock DS, Feliciano CE, Wood TM, Melendez JA, Rodriguez AM, Schumacker PT. Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1alpha during hypoxia: a mechanism of O2 sensing. The Journal of Biological Chemistry. 275: 25130-8. PMID 10833514 DOI: 10.1074/Jbc.M001914200 |
0.456 |
|
| 2000 |
Chandel NS, Schumacker PT. Cellular oxygen sensing by mitochondria: old questions, new insight. Journal of Applied Physiology (Bethesda, Md. : 1985). 88: 1880-9. PMID 10797153 DOI: 10.1152/Jappl.2000.88.5.1880 |
0.395 |
|
| 2000 |
Vander Heiden MG, Chandel NS, Li XX, Schumacker PT, Colombini M, Thompson CB. Outer mitochondrial membrane permeability can regulate coupled respiration and cell survival. Proceedings of the National Academy of Sciences of the United States of America. 97: 4666-71. PMID 10781072 DOI: 10.1073/Pnas.090082297 |
0.427 |
|
| 1999 |
Ali MH, Schlidt SA, Chandel NS, Hynes KL, Schumacker PT, Gewertz BL. Endothelial permeability and IL-6 production during hypoxia: role of ROS in signal transduction. The American Journal of Physiology. 277: L1057-65. PMID 10564193 DOI: 10.1152/Ajplung.1999.277.5.L1057 |
0.367 |
|
| 1999 |
Chandel NS, Schumacker PT. Cells depleted of mitochondrial DNA (rho0) yield insight into physiological mechanisms. Febs Letters. 454: 173-6. PMID 10431801 DOI: 10.1016/S0014-5793(99)00783-8 |
0.524 |
|
| 1999 |
Vander Heiden MG, Chandel NS, Schumacker PT, Thompson CB. Bcl-x(L) prevents cell death following growth factor withdrawal by facilitating mitochondrial ATP/ADP exchange Molecular Cell. 3: 159-167. PMID 10078199 DOI: 10.1016/S1097-2765(00)80307-X |
0.488 |
|
| 1998 |
Chandel NS, Maltepe E, Goldwasser E, Mathieu CE, Simon MC, Schumacker PT. Mitochondrial reactive oxygen species trigger hypoxia-induced transcription. Proceedings of the National Academy of Sciences of the United States of America. 95: 11715-20. PMID 9751731 DOI: 10.1073/Pnas.95.20.11715 |
0.51 |
|
| 1998 |
Duranteau J, Chandel NS, Kulisz A, Shao Z, Schumacker PT. Intracellular signaling by reactive oxygen species during hypoxia in cardiomyocytes. The Journal of Biological Chemistry. 273: 11619-24. PMID 9565580 DOI: 10.1074/Jbc.273.19.11619 |
0.436 |
|
| 1998 |
Budinger GR, Duranteau J, Chandel NS, Schumacker PT. Hibernation during hypoxia in cardiomyocytes. Role of mitochondria as the O2 sensor. The Journal of Biological Chemistry. 273: 3320-6. PMID 9452449 DOI: 10.1074/Jbc.273.6.3320 |
0.384 |
|
| 1997 |
Vander Heiden MG, Chandel NS, Williamson EK, Schumacker PT, Thompson CB. Bcl-x(L) regulates the membrane potential and volume homeostasis of mitochondria Cell. 91: 627-637. PMID 9393856 DOI: 10.1016/S0092-8674(00)80450-X |
0.469 |
|
| 1997 |
Chandel NS, Budinger GR, Choe SH, Schumacker PT. Cellular respiration during hypoxia. Role of cytochrome oxidase as the oxygen sensor in hepatocytes. The Journal of Biological Chemistry. 272: 18808-16. PMID 9228055 DOI: 10.1074/Jbc.272.30.18808 |
0.438 |
|
| 1996 |
Chandel NS, Budinger GR, Schumacker PT. Molecular oxygen modulates cytochrome c oxidase function. The Journal of Biological Chemistry. 271: 18672-7. PMID 8702521 DOI: 10.1074/Jbc.271.31.18672 |
0.35 |
|
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