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Jan B. Hoek - Publications

Molecular Pharmacology and Structural Biology Thomas Jefferson University, Philadelphia, PA, United States 
Biochemistry, Pharmacology

103 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Barnhart BK, Kan T, Srivastava A, Wessner CE, Waters J, Ambelil M, Eisenbrey JR, Hoek JB, Vadigepalli R. Longitudinal ultrasound imaging and network modeling in rats reveal sex-dependent suppression of liver regeneration after resection in alcoholic liver disease. Frontiers in Physiology. 14: 1102393. PMID 36969577 DOI: 10.3389/fphys.2023.1102393  0.366
2021 Gaspers LD, Thomas AP, Hoek JB, Bartlett PJ. Ethanol Disrupts Hormone-Induced Calcium Signaling in Liver. Function (Oxford, England). 2: zqab002. PMID 33604575 DOI: 10.1093/function/zqab002  0.327
2020 Campos G, Schmidt-Heck W, De Smedt J, Widera A, Ghallab A, Pütter L, González D, Edlund K, Cadenas C, Marchan R, Guthke R, Verfaillie C, Hetz C, Sachinidis A, Braeuning A, ... ... Hoek J, et al. Inflammation-associated suppression of metabolic gene networks in acute and chronic liver disease. Archives of Toxicology. PMID 31919559 DOI: 10.1007/S00204-019-02630-3  0.404
2020 Barnhart B, Chopra C, Achanta S, Hoek JB, Vadigepalli R. Compensatory Enzyme Expression In Response To Chronic Ethanol Intake And Partial Hepatectomy Disrupts Zone‐Specific Organization Of Lobular Metabolism In The Rat Liver The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.07230  0.439
2020 Barnhart B, Kan T, Wessner CE, Eisenbrey JR, Hoek JB, Vadigepalli R. Sex‐dependent Liver Volume Recovery and Hemodynamics Measured by Non‐Invasive Ultrasound Imaging after Partial Hepatectomy in Rats The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.07223  0.338
2018 Achanta S, Verma A, Srivastava A, Nilakantan H, Hoek JB, Vadigepalli R. Single cell gene expression analysis identifies chronic alcoholmediated shift in hepatocyte molecular states after partial hepatectomy. Gene Expression. PMID 30189915 DOI: 10.3727/105221618X15361728786767  0.358
2017 Bartlett PJ, Antony AN, Agarwal A, Hilly M, Prince VL, Combettes L, Hoek JB, Gaspers LD. Chronic alcohol feeding potentiates hormone-induced calcium signalling in hepatocytes. The Journal of Physiology. PMID 28220501 DOI: 10.1113/JP273891  0.306
2016 Kuttippurathu L, Patra B, Cook D, Hoek JB, Vadigepalli R. Pattern analysis uncovers a chronic ethanol-induced disruption of the switch-like dynamics of C/EBP-β and C/EBP-α genome-wide binding during liver regeneration. Physiological Genomics. physiolgenomics.0009. PMID 27815535 DOI: 10.1152/Physiolgenomics.00097.2016  0.385
2016 Juskeviciute E, Dippold RP, Antony AN, Swarup A, Vadigepalli R, Hoek JB. Inhibition of miR-21 rescues liver regeneration after partial hepatectomy in ethanol-fed rats. American Journal of Physiology. Gastrointestinal and Liver Physiology. ajpgi.00292.2016. PMID 27634014 DOI: 10.1152/Ajpgi.00292.2016  0.783
2016 Kuttippurathu L, Juskeviciute E, Dippold RP, Hoek JB, Vadigepalli R. A novel comparative pattern analysis approach identifies chronic alcohol mediated dysregulation of transcriptomic dynamics during liver regeneration. Bmc Genomics. 17: 260. PMID 27012785 DOI: 10.1186/S12864-016-2492-X  0.789
2016 Antony AN, Paillard M, Moffat C, Juskeviciute E, Correnti J, Bolon B, Rubin E, Csordás G, Seifert EL, Hoek JB, Hajnóczky G. MICU1 regulation of mitochondrial Ca(2+) uptake dictates survival and tissue regeneration. Nature Communications. 7: 10955. PMID 26956930 DOI: 10.1038/Ncomms10955  0.743
2016 Antony AN, Paillard M, Moffat C, Juskeviciute E, Rubin E, Csordas G, Seifert E, Hajnoczky G, Hoek JB. MICU1 Regulation of Mitochondrial Calcium Uptake is Crucial for Liver Regeneration Biophysical Journal. 110: 311a. DOI: 10.1016/J.Bpj.2015.11.1672  0.421
2016 Paillard M, Antony AN, Moffat C, Juskeviciute E, Bolon B, Rubin E, Csordás G, Seifert EL, Hoek JB, Hajnóczky G. MICU1, the Ca2+ Sensing Regulator of the Mitochondrial Ca2+ Uniporter is Required for Adaptation to Postnatal Life Biophysical Journal. 110: 311a. DOI: 10.1016/J.Bpj.2015.11.1671  0.325
2015 Nilakantan H, Kuttippurathu L, Parrish A, Hoek JB, Vadigepalli R. In Vivo Zonal Variation and Liver Cell-Type Specific NF-κB Localization after Chronic Adaptation to Ethanol and following Partial Hepatectomy. Plos One. 10: e0140236. PMID 26452159 DOI: 10.1371/Journal.Pone.0140236  0.318
2015 Cook DJ, Patra B, Kuttippurathu L, Hoek JB, Vadigepalli R. A novel, dynamic pattern-based analysis of NF-κB binding during the priming phase of liver regeneration reveals switch-like functional regulation of target genes. Frontiers in Physiology. 6: 189. PMID 26217230 DOI: 10.3389/Fphys.2015.00189  0.309
2015 Correnti JM, Cook D, Aksamitiene E, Swarup A, Ogunnaike B, Vadigepalli R, Hoek JB. Adiponectin fine-tuning of liver regeneration dynamics revealed through cellular network modelling. The Journal of Physiology. 593: 365-83. PMID 25630259 DOI: 10.1113/Jphysiol.2014.284109  0.761
2014 Correnti JM, Cook D, Aksamitiene E, Swarup A, Ogunnaike B, Vadigepalli R, Hoek JB. Adiponectin fine-tuning of liver regeneration dynamics revealed through cellular network modeling. The Journal of Physiology. PMID 25384784 DOI: 10.1113/jphysiol.2014.284109  0.752
2014 Romero F, Shah D, Duong M, Stafstrom W, Hoek JB, Kallen CB, Lang CH, Summer R. Chronic alcohol ingestion in rats alters lung metabolism, promotes lipid accumulation, and impairs alveolar macrophage functions. American Journal of Respiratory Cell and Molecular Biology. 51: 840-9. PMID 24940828 DOI: 10.1165/Rcmb.2014-0127Oc  0.345
2014 Correnti JM, Juskeviciute E, Swarup A, Hoek JB. Pharmacological ceramide reduction alleviates alcohol-induced steatosis and hepatomegaly in adiponectin knockout mice. American Journal of Physiology. Gastrointestinal and Liver Physiology. 306: G959-73. PMID 24742988 DOI: 10.1152/Ajpgi.00395.2013  0.762
2014 Neill T, Torres A, Buraschi S, Owens RT, Hoek JB, Baffa R, Iozzo RV. Decorin induces mitophagy in breast carcinoma cells via peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) and mitostatin. The Journal of Biological Chemistry. 289: 4952-68. PMID 24403067 DOI: 10.1074/Jbc.M113.512566  0.642
2013 Dippold RP, Vadigepalli R, Gonye GE, Patra B, Hoek JB. Chronic ethanol feeding alters miRNA expression dynamics during liver regeneration. Alcoholism, Clinical and Experimental Research. 37: E59-69. PMID 22823254 DOI: 10.1111/J.1530-0277.2012.01852.X  0.785
2013 Noronha Antony A, Moffat C, Swarup A, Seifert E, Hoek JB. Substrate Oxidation Control of Respiratory Rates in Primary Hepatocytes Biophysical Journal. 104: 302a. DOI: 10.1016/J.Bpj.2012.11.1684  0.308
2013 Csordas G, Mankus D, Anil Noronha A, Hoek J, Mannella C, Hajnoczky G. ER-Mitochondrial Ultrastructure in the Liver of Normal and Ethnaol-Fed Rats Biophysical Journal. 104: 216a. DOI: 10.1016/J.Bpj.2012.11.1221  0.441
2012 Dippold RP, Vadigepalli R, Gonye GE, Hoek JB. Chronic ethanol feeding enhances miR-21 induction during liver regeneration while inhibiting proliferation in rats. American Journal of Physiology. Gastrointestinal and Liver Physiology. 303: G733-43. PMID 22790595 DOI: 10.1152/Ajpgi.00019.2012  0.77
2012 Freeman K, Brureau A, Vadigepalli R, Staehle MM, Brureau MM, Gonye GE, Hoek JB, Hooper DC, Schwaber JS. Temporal changes in innate immune signals in a rat model of alcohol withdrawal in emotional and cardiorespiratory homeostatic nuclei. Journal of Neuroinflammation. 9: 97. PMID 22626265 DOI: 10.1186/1742-2094-9-97  0.328
2012 Das S, Hajnóczky N, Antony AN, Csordás G, Gaspers LD, Clemens DL, Hoek JB, Hajnóczky G. Mitochondrial morphology and dynamics in hepatocytes from normal and ethanol-fed rats. PflüGers Archiv : European Journal of Physiology. 464: 101-9. PMID 22526459 DOI: 10.1007/S00424-012-1100-4  0.462
2012 Freeman K, Staehle MM, Gümüş ZH, Vadigepalli R, Gonye GE, Nichols CN, Ogunnaike BA, Hoek JB, Schwaber JS. Rapid temporal changes in the expression of a set of neuromodulatory genes during alcohol withdrawal in the dorsal vagal complex: molecular evidence of homeostatic disturbance. Alcoholism, Clinical and Experimental Research. 36: 1688-700. PMID 22486438 DOI: 10.1111/J.1530-0277.2012.01791.X  0.319
2012 Csordas G, Mankus D, Shaikh T, Meng X, Hoek J, Mannella C, Hajnoczky G. SR-Mitochondrial Ultrastructure in the Heart of Normal and Ethanol-Fed Rats Biophysical Journal. 102: 437a. DOI: 10.1016/J.Bpj.2011.11.2393  0.403
2010 Maxwell CR, Spangenberg RJ, Hoek JB, Silberstein SD, Oshinsky ML. Acetate causes alcohol hangover headache in rats. Plos One. 5: e15963. PMID 21209842 DOI: 10.1371/Journal.Pone.0015963  0.406
2010 Bansal S, Liu CP, Sepuri NB, Anandatheerthavarada HK, Selvaraj V, Hoek J, Milne GL, Guengerich FP, Avadhani NG. Mitochondria-targeted cytochrome P450 2E1 induces oxidative damage and augments alcohol-mediated oxidative stress. The Journal of Biological Chemistry. 285: 24609-19. PMID 20529841 DOI: 10.1074/Jbc.M110.121822  0.397
2008 Juskeviciute E, Vadigepalli R, Hoek JB. Temporal and functional profile of the transcriptional regulatory network in the early regenerative response to partial hepatectomy in the rat. Bmc Genomics. 9: 527. PMID 18990226 DOI: 10.1186/1471-2164-9-527  0.338
2008 Crumm S, Cofan M, Juskeviciute E, Hoek JB. Adenine nucleotide changes in the remnant liver: An early signal for regeneration after partial hepatectomy. Hepatology (Baltimore, Md.). 48: 898-908. PMID 18697206 DOI: 10.1002/Hep.22421  0.389
2008 Pastorino JG, Hoek JB. Regulation of hexokinase binding to VDAC. Journal of Bioenergetics and Biomembranes. 40: 171-82. PMID 18683036 DOI: 10.1007/S10863-008-9148-8  0.307
2005 Szabo G, Hoek JB, Darley-Usmar V, Hajnoczky G, Knudsen T, Mochly-Rosen D, Zakhari S. RSA 2004: combined basic research satellite symposium - session three: alcohol and mitochondrial metabolism: at the crossroads of life and death. Alcoholism, Clinical and Experimental Research. 29: 1749-52. PMID 16205376 DOI: 10.1097/01.Alc.0000179318.48376.Cd  0.408
2005 Hoek J, Thiele GM, Klassen LW, Mandrekar P, Zakhari S, Cook RT, Ray NB, Happel KI, Kolls JK, Kovacs EJ, Szab G. RSA 2004: combined basic research satellite symposium-mechanisms of alcohol-mediated organ and tissue damage: inflammation and immunity and alcohol and mitochondrial metabolism: at the crossroads of life and death session one: alcohol, cellular and organ damage. Alcoholism, Clinical and Experimental Research. 29: 1735-43. PMID 16205374 DOI: 10.1097/01.Alc.0000179313.64522.56  0.348
2005 Lakshman R, Cederbaum AI, Hoek JB, Konishi M, Koop D, Donohu TM. Use of CYP2E1-transfected human liver cell lines in elucidating the actions of ethanol. Alcoholism, Clinical and Experimental Research. 29: 1726-34. PMID 16205373 DOI: 10.1097/01.Alc.0000179379.03078.8F  0.404
2005 Covarrubias MY, Khan RL, Vadigepalli R, Hoek JB, Schwaber JS. Chronic alcohol exposure alters transcription broadly in a key integrative brain nucleus for homeostasis: the nucleus tractus solitarius. Physiological Genomics. 24: 45-58. PMID 16189278 DOI: 10.1152/Physiolgenomics.00184.2005  0.334
2005 Hajnóczky G, Buzas CJ, Pacher P, Hoek JB, Rubin E. Alcohol and mitochondria in cardiac apoptosis: mechanisms and visualization. Alcoholism, Clinical and Experimental Research. 29: 693-701. PMID 15897712 DOI: 10.1097/01.Alc.0000163493.45344.7A  0.355
2005 Shulga N, Hoek JB, Pastorino JG. Elevated PTEN levels account for the increased sensitivity of ethanol-exposed cells to tumor necrosis factor-induced cytotoxicity. The Journal of Biological Chemistry. 280: 9416-24. PMID 15623531 DOI: 10.1074/Jbc.M409505200  0.431
2004 Rubin R, Harrison R, Chen XF, Corzitotto J, Hoek JB, Hallak H. Inhibition of insulin-like growth factor I receptor tyrosine kinase by ethanol. Biochemical Pharmacology. 68: 2009-17. PMID 15476672 DOI: 10.1016/J.Bcp.2004.06.032  0.344
2004 Hoek JB, Pastorino JG. Cellular signaling mechanisms in alcohol-induced liver damage. Seminars in Liver Disease. 24: 257-72. PMID 15349804 DOI: 10.1055/S-2004-832939  0.487
2003 Pastorino JG, Shulga N, Hoek JB. TNF-alpha-induced cell death in ethanol-exposed cells depends on p38 MAPK signaling but is independent of Bid and caspase-8. American Journal of Physiology. Gastrointestinal and Liver Physiology. 285: G503-16. PMID 12748063 DOI: 10.1152/Ajpgi.00442.2002  0.393
2003 Davies AM, Hershman S, Stabley GJ, Hoek JB, Peterson J, Cahill A. A Ca2+-induced mitochondrial permeability transition causes complete release of rat liver endonuclease G activity from its exclusive location within the mitochondrial intermembrane space. Identification of a novel endo-exonuclease activity residing within the mitochondrial matrix. Nucleic Acids Research. 31: 1364-73. PMID 12582256 DOI: 10.1093/Nar/Gkg205  0.332
2002 Hoek JB, Pastorino JG. Ethanol, oxidative stress, and cytokine-induced liver cell injury. Alcohol (Fayetteville, N.Y.). 27: 63-8. PMID 12062639 DOI: 10.1016/S0741-8329(02)00215-X  0.444
2002 Hoek JB, Cahill A, Pastorino JG. Alcohol and mitochondria: a dysfunctional relationship. Gastroenterology. 122: 2049-63. PMID 12055609 DOI: 10.1053/Gast.2002.33613  0.419
2000 Nojiri S, Hoek J. Suppression of epidermal growth factor-induced phospholipase C activation associated with actin rearrangement in rat hepatocytes in primary culture Hepatology. 32: 947-957. PMID 11050044 DOI: 10.1053/Jhep.2000.18662  0.312
2000 Pastorino JG, Hoek JB. Ethanol potentiates tumor necrosis factor-α cytotoxicity in hepatoma cells and primary rat hepatocytes by promoting induction of the mitochondrial permeability transition Hepatology. 31: 1141-1152. PMID 10796891 DOI: 10.1053/He.2000.7013  0.375
2000 Miro O, Robert J, Casademont J, Alonso JR, Nicolas JM, Fernandez-Sola J, Urbano-Marquez A, Hoek JB, Cardellach F. Heart Mitochondrial Respiratory Chain Complexes Are Functionally Unaffected in Heavy Ethanol Drinkers Without Cardiomyopathy Alcoholism: Clinical and Experimental Research. 24: 859-864. DOI: 10.1111/J.1530-0277.2000.Tb02066.X  0.352
2000 MARCINKEVICIUTE A, MILDAZIENE V, CRUMM S, DEMIN O, HOEK JB, KHOLODENKO B. Kinetics and control of oxidative phosphorylation in rat liver mitochondria after chronic ethanol feeding Biochemical Journal. 349: 519-526. DOI: 10.1042/bj3490519  0.309
1999 Diehl AM, Hoek JB. Mitochondrial uncoupling: Role of uncoupling protein anion carriers and relationship to thermogenesis and weight control 'The benefits of losing control' Journal of Bioenergetics and Biomembranes. 31: 493-506. PMID 10653477 DOI: 10.1023/A:1005452624640  0.319
1999 Pastorino JG, Marcineviciute A, Cahill A, Hoek JB. Potentiation by chronic ethanol treatment of the mitochondrial permeability transition. Biochemical and Biophysical Research Communications. 265: 405-409. PMID 10558880 DOI: 10.1006/Bbrc.1999.1696  0.41
1999 Pastorino JG, Tafani M, Rothman RJ, Marcineviciute A, Hoek JB, Farber JL. Functional Consequences of the Sustained or Transient Activation by Bax of the Mitochondrial Permeability Transition Pore Journal of Biological Chemistry. 274: 31734-31739. PMID 10531385 DOI: 10.1074/Jbc.274.44.31734  0.307
1999 Kholodenko BN, Demin OV, Moehren G, Hoek JB. Quantification of short term signaling by the epidermal growth factor receptor Journal of Biological Chemistry. 274: 30169-30181. PMID 10514507 DOI: 10.1074/Jbc.274.42.30169  0.3
1999 Cahill A, Stabley GJ, Wang X, Hoek JB. Chronic ethanol consumption causes alterations in the structural integrity of mitochondrial DNA in aged rats. Hepatology. 30: 881-888. PMID 10498638 DOI: 10.1002/Hep.510300434  0.426
1999 Hoek JB. Endotoxin and alcoholic liver disease: Tolerance and susceptibility Hepatology. 29: 1602-1604. PMID 10216149 DOI: 10.1002/Hep.510290536  0.374
1998 Hoek JB, Kholodenko BN. The intracellular signaling network as a target for ethanol Alcoholism: Clinical and Experimental Research. 22. PMID 9727641 DOI: 10.1111/J.1530-0277.1998.Tb04007.X  0.355
1998 Larsson C, Thomas AP, Hoek JB. Carbachol-stimulated Ca2+ increase in single neuroblastoma SH-SY5Y cells: effects of ethanol. Alcoholism, Clinical and Experimental Research. 22: 637-45. PMID 9622444 DOI: 10.1111/J.1530-0277.1998.Tb04305.X  0.341
1997 Cahill A, Wang X, Hoek JB. Increased Oxidative Damage To Mitochondrial Dna Following Chronic Ethanol Consumption Biochemical and Biophysical Research Communications. 235: 286-290. PMID 9199183 DOI: 10.1006/Bbrc.1997.6774  0.4
1997 Saso K, Moehren G, Higashi K, Hoek JB. Differential inhibition of epidermal growth factor signaling pathways in rat hepatocytes by long-term ethanol treatment Gastroenterology. 112: 2073-2088. PMID 9178701 DOI: 10.1053/Gast.1997.V112.Pm9178701  0.441
1997 Ponnappa BC, Marciniak R, Schneider T, Hoek JB, Rubin E. Ethanol consumption and susceptibility of the pancreas to cerulein-induced pancreatitis. Pancreas. 14: 150-157. PMID 9057187 DOI: 10.1097/00006676-199703000-00007  0.42
1996 Resnicoff M, Cui S, Coppola D, Hoek JB, Rubin R. Ethanol‐Induced Inhibition of Cell Proliferation Is Modulated by Insulin‐Like Growth Factor‐I Receptor Levels Alcoholism: Clinical and Experimental Research. 20: 961-966. PMID 8865975 DOI: 10.1111/J.1530-0277.1996.Tb05278.X  0.36
1996 Saso K, Higashi K, Nomura T, Hoshino M, Ito M, Moehren G, Hoek JB. Inhibitory Effect of Ethanol on Hepatocyte Growth Factor-Induced DNA Synthesis and Ca2+ Mobilization in Rat Hepatocytes Alcoholism: Clinical and Experimental Research. 20: 330A-334A. DOI: 10.1111/J.1530-0277.1996.Tb01802.X  0.395
1996 Nomura T, Higashi K, Hoshino M, Saso K, Itou M, Hoek JB. Effect of Glutathione on Inositol 1,4,5-Triphosphate-Induced Ca2+ Release in Permeabilized Hepatocytes from Control and Chronic Ethanol-Fed Rats Alcoholism: Clinical and Experimental Research. 20: 325A-329A. DOI: 10.1111/J.1530-0277.1996.Tb01801.X  0.391
1996 Higashi K, Hoshino M, Nomura T, Saso K, Ito M, Hoek JB. Interaction of Protein Phosphatases and Ethanol on Phospholipase C-Mediated Intracellular Signal Transduction Processes in Rat Hepatocytes: Role of Protein Kinase A Alcoholism: Clinical and Experimental Research. 20: 320A-324A. DOI: 10.1111/J.1530-0277.1996.Tb01800.X  0.382
1995 Pastorino JG, Snyder JW, Hoek JB, Farber JL. Ca2+ depletion prevents anoxic death of hepatocytes by inhibiting mitochondrial permeability transition. The American Journal of Physiology. 268: C676-85. PMID 7900774 DOI: 10.1152/Ajpcell.1995.268.3.C676  0.317
1995 Larsson C, Simonsson P, Hoek JB, Alling C. Ethanol inhibits the peak of muscarinic receptor-stimulated formation of inositol 1,4,5-trisphosphate in neuroblastoma SH-SY5Y cells Biochemical Pharmacology. 50: 647-654. PMID 7669067 DOI: 10.1016/0006-2952(95)00179-4  0.381
1995 Hoek JB, Farber JL, Thomas AP, Wang X. Calcium ion-dependent signalling and mitochondrial dysfunction: mitochondrial calcium uptake during hormonal stimulation in intact liver cells and its implication for the mitochondrial permeability transition Biochimica Et Biophysica Acta. 1271: 93-102. PMID 7599232 DOI: 10.1016/0925-4439(95)00015-V  0.335
1995 Victorov AV, Hoek JB. Secretion of prostaglandins elicited by lipopolysaccharide and ethanol in cultured rat Kupffer cells Biochemical and Biophysical Research Communications. 215: 691-697. PMID 7488010 DOI: 10.1006/Bbrc.1995.2519  0.361
1994 Benistant C, Moehren G, Gustavsson L, Torres-Marquez E, Hoek JB, Rubin R. Leupeptin inhibits phospholipases D and C activation in rat hepatocytes. Biochimica Et Biophysica Acta. 1223: 84-90. PMID 8061057 DOI: 10.1016/0167-4889(94)90076-0  0.359
1993 Ponnappa BC, Dodge GR, Dudkowski B, Hoek JB, Iozzo RV, Rubin E. Stimulation of protein synthesis in isolated pancreatic acini from chronically ethanol-fed rats is due to alterations in post-transcriptional regulation. Biochimica Et Biophysica Acta. 1158: 113-9. PMID 7691180 DOI: 10.1016/0304-4165(93)90004-R  0.39
1992 Ala‐Kokko L, Günzler V, Hoek JB, Rubin E, Prockop DJ. Hepatic fibrosis in rats produced by carbon tetrachloride and dimethylnitrosamine: Observations suggesting immunoassays of serum for the 75 fragment of type IV collagen are a more sensitive index of liver damage than immunoassays for the NH2‐terminal propeptide of type III procollagen Hepatology. 16: 167-172. PMID 1618469 DOI: 10.1002/Hep.1840160128  0.319
1992 Cardellach F, Galofré J, Grau JM, Casademont J, Hoek JB, Rubin E, Urbano-Márquez A. Oxidative metabolism in muscle mitochondria from patients with chronic alcoholism. Annals of Neurology. 31: 515-8. PMID 1596087 DOI: 10.1002/Ana.410310509  0.341
1992 Hoek JB, Thomas AP, Rooney TA, Higashi K, Rubin E. Ethanol and signal transduction in the liver The Faseb Journal. 6: 2386-2396. DOI: 10.1096/Fasebj.6.7.1563591  0.442
1991 Gustavsson L, Moehren G, Hoek JB. Phosphatidylethanol formation in rat hepatocytes. Annals of the New York Academy of Sciences. 625: 438-440. PMID 2058899 DOI: 10.1111/J.1749-6632.1991.Tb33873.X  0.301
1991 Cardellach F, Taraschi TF, Ellingson JS, Stubbs CD, Rubin E, Hoek JB. Maintenance of structural and functional characteristics of skeletal-muscle mitochondria and sarcoplasmic-reticular membranes after chronic ethanol treatment. The Biochemical Journal. 274: 565-73. PMID 1848761 DOI: 10.1042/Bj2740565  0.409
1991 Hoek JB, Higashi K. Effects of alcohol on polyphosphoinositide-mediated intracellular signaling Annals of the New York Academy of Sciences. 625: 375-387. PMID 1647733 DOI: 10.1111/J.1749-6632.1991.Tb33865.X  0.302
1990 Hoek JB, Rubin E. Alcohol and membrane-associated signal transduction Alcohol and Alcoholism. 25: 143-156. PMID 2198031 DOI: 10.1093/Oxfordjournals.Alcalc.A044989  0.428
1990 Hoek JB, Taraschi TF, Higashi K, Rubin E, Thomas AP. Phospholipase C activation by ethanol in rat hepatocytes is unaffected by chronic ethanol feeding Biochemical Journal. 272: 59-64. PMID 2176085 DOI: 10.1042/Bj2720059  0.432
1990 Rubin R, Hoek JB. Inhibition of ethanol-induced platelet activation by agents that elevate cAMP Thrombosis Research. 58: 625-632. PMID 2166973 DOI: 10.1016/0049-3848(90)90308-Y  0.361
1990 Ponnappa BC, Hoek JB, Jubinski L, Rubin E. Ethanol withdrawal stimulates protein synthesis in rat pancreatic lobules. Biochimica Et Biophysica Acta. 1036: 107-112. PMID 1699603 DOI: 10.1016/0304-4165(90)90021-N  0.385
1989 Masaki N, Thomas AP, Hoek JB, Farber JL. Intracellular acidosis protects cultured hepatocytes from the toxic consequences of a loss of mitochondrial energization. Archives of Biochemistry and Biophysics. 272: 152-161. PMID 2735760 DOI: 10.1016/0003-9861(89)90206-3  0.306
1988 Ponnappa BC, Hoek JB, Jubinski L, Rubin E. Effect of chronic ethanol ingestion on pancreatic protein synthesis Bba - General Subjects. 966: 390-402. PMID 3416016 DOI: 10.1016/0304-4165(88)90090-6  0.378
1988 Rubin R, Hoek JB. Alcohol-induced stimulation of phospholipase C in human platelets requires G-protein activation Biochemical Journal. 254: 147-153. PMID 3140795 DOI: 10.1042/Bj2540147  0.39
1988 Hoek JB, Rubin R, Thomas A. Ethanol-induced phospholipase C activation is inhibited by phorbol esters in isolated hepatocytes. Biochemical Journal. 251: 865-871. PMID 3137925 DOI: 10.1042/Bj2510865  0.391
1988 Hoek JB, Taraschi TF. Cellular adaptation to ethanol Trends in Biochemical Sciences. 13: 269-274. PMID 3076725 DOI: 10.1016/0968-0004(88)90161-2  0.347
1988 Dorio RJ, Hoek JB, Rubin E, Forman HJ. Ethanol modulation of rat alveolar macrophage superoxide production. Biochemical Pharmacology. 37: 3528-3531. PMID 2844192 DOI: 10.1016/0006-2952(88)90708-3  0.357
1988 Rubin R, Hoek JB. Ethanol-induced stimulation of phosphoinositide turnover and calcium influx in isolated hepatocytes Biochemical Pharmacology. 37: 2461-2466. PMID 2839195 DOI: 10.1016/0006-2952(88)90374-7  0.378
1988 Hoek JB, Taraschi TF, Rubin E. Functional implications of the interaction of ethanol with biologic membranes: actions of ethanol on hormonal signal transduction systems. Seminars in Liver Disease. 8: 36-46. PMID 2834828 DOI: 10.1055/S-2008-1040527  0.35
1988 Rubin R, Ponnappa BC, Thomas AP, Hoek JB. Ethanol stimulates shape change in human platelets by activation of phosphoinositide-specific phospholipase C. Archives of Biochemistry and Biophysics. 260: 480-492. PMID 2829732 DOI: 10.1016/0003-9861(88)90472-9  0.366
1987 Rubin R, Thomas AP, Hoek JB. Ethanol does not stimulate guanine nucleotide-induced activation of phospholipase C in permeabilized hepatocytes. Archives of Biochemistry and Biophysics. 256: 29-38. PMID 3606126 DOI: 10.1016/0003-9861(87)90422-X  0.367
1987 Hoek JB. Effects of ethanol on calcium homeostasis in rat hepatocytes and its interaction with the phosphoinositide-dependent pathway of signal transduction Annals of the New York Academy of Sciences. 492: 212-223. PMID 3037963 DOI: 10.1111/J.1749-6632.1987.Tb48671.X  0.374
1987 DORIO RJ, HOEK JB, FORMAN HJ, RUBIN E. The Effect of Ethanol on Superoxide Production in Alveolar Macrophages Annals of the New York Academy of Sciences. 492: 324-326. DOI: 10.1111/J.1749-6632.1987.Tb48684.X  0.328
1987 THOMAS AP, HOEK JB, RUBIN E. Elevation of Inositol 1,4,5-Trisphosphate Levels after Acute Ethanol Treatment of Rat Hepatocytes Annals of the New York Academy of Sciences. 492: 250-255. DOI: 10.1111/J.1749-6632.1987.Tb48676.X  0.385
1987 RUBIN R, HOEK JB. Ethanol-Induced Activation of Polyphosphoinositide Turnover in Rat Hepatocytes Annals of the New York Academy of Sciences. 492: 248-249. DOI: 10.1111/J.1749-6632.1987.Tb48675.X  0.412
1987 HOEK JB, RUBIN R, THOMAS AP. Phorbol Esters Inhibit Ethanol-Induced Calcium Mobilization and Polyphosphoinositide Turnover in Isolated Hepatocytes Annals of the New York Academy of Sciences. 492: 245-247. DOI: 10.1111/J.1749-6632.1987.Tb48674.X  0.354
1981 Williamson JR, Cooper RH, Hoek JB. Role of calcium in the hormonal regulation of liver metabolism. Biochimica Et Biophysica Acta. 639: 243-95. PMID 7039675 DOI: 10.1016/0304-4173(81)90012-4  0.333
1980 Wanders RJ, Hoek JB, Tager JM. Origin of the ammonia found in protein-free extracts of rat-liver mitochondria and rat hepatocytes. European Journal of Biochemistry. 110: 197-202. PMID 7439158 DOI: 10.1111/J.1432-1033.1980.Tb04855.X  0.51
1974 Hoek JB, Ernster L, de Haan EJ, Tager JM. The nicotinamide nucleotide specificity of glutamate dehydrogenase in intact rat-liver mitochondria. Biochimica Et Biophysica Acta. 333: 546-59. PMID 4152605 DOI: 10.1016/0005-2728(74)90138-8  0.525
1973 Hoek JB, Tager JM. The oxidoreduction state of free NAD(P) and mass-action ratio of total nicotinamide nucleotides in isolated ratliver mitochondria Bba - Bioenergetics. 325: 197-212. PMID 4148618 DOI: 10.1016/0005-2728(73)90096-0  0.453
1972 Meijer AJ, Brouwer A, Reijngoud DJ, Hoek JB, Tager JM. Transport of glutamate in rat-liver mitochondria. Biochimica Et Biophysica Acta. 283: 421-9. PMID 4649357 DOI: 10.1016/0005-2728(72)90259-9  0.5
1971 Lofrumento NE, Hoek JB, Meyer AJ, Tager JM. Phosphate transport in rat-liver mitochondria. Biochimica Et Biophysica Acta. 226: 297-308. PMID 5575160 DOI: 10.1016/0005-2728(71)90096-X  0.518
1969 Hoek JB, Charles R, De Haan EJ, Tager JM. Glutamate oxidation in rat-liver homogenate. Biochimica Et Biophysica Acta. 172: 407-16. PMID 5782247 DOI: 10.1016/0005-2728(69)90137-6  0.495
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