William T. Gerthoffer - Publications

Affiliations: 
College of Medicine University of South Alabama, Mobile, AL, United States 
Area:
Cell Biology, Biochemistry, Molecular Biology

32 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Ramelli SC, Gerthoffer WT. MicroRNA Targets for Asthma Therapy. Advances in Experimental Medicine and Biology. 1303: 89-105. PMID 33788189 DOI: 10.1007/978-3-030-63046-1_6  0.4
2020 Ramelli SC, Comer BS, McLendon JM, Sandy LL, Ferretti AP, Barrington R, Sparks J, Matar M, Fewell J, Gerthoffer WT. Nanoparticle Delivery of Anti-inflammatory LNA Oligonucleotides Prevents Airway Inflammation in a HDM Model of Asthma. Molecular Therapy. Nucleic Acids. 19: 1000-1014. PMID 32044723 DOI: 10.1016/J.Omtn.2019.12.033  0.44
2018 Ba M, Rawat S, Lao R, Grous M, Salmon M, Halayko AJ, Gerthoffer WT, Singer CA. Differential regulation of cytokine and chemokine expression by MK2 and MK3 in airway smooth muscle cells. Pulmonary Pharmacology & Therapeutics. PMID 30205157 DOI: 10.1016/J.Pupt.2018.09.004  0.44
2016 Ramelli S, McLendon JM, Ferretti AP, Fewell J, Barrington R, Gerthoffer WT. Antisense MicroRNA Therapy of Airway Remodeling in House Dust Mite-sensitized Mice. Annals of the American Thoracic Society. 13: S101-2. PMID 27027939 DOI: 10.1513/Annalsats.201507-414Mg  0.44
2015 McLendon JM, Joshi SR, Sparks J, Matar M, Fewell JG, Abe K, Oka M, McMurtry IF, Gerthoffer WT. Lipid nanoparticle delivery of a microRNA-145 inhibitor improves experimental pulmonary hypertension. Journal of Controlled Release : Official Journal of the Controlled Release Society. 210: 67-75. PMID 25979327 DOI: 10.1016/J.Jconrel.2015.05.261  0.44
2015 Comer BS, Ba M, Singer CA, Gerthoffer WT. Epigenetic targets for novel therapies of lung diseases. Pharmacology & Therapeutics. 147: 91-110. PMID 25448041 DOI: 10.1016/J.Pharmthera.2014.11.006  0.44
2015 Comer BS, Camoretti-Mercado B, Kogut PC, Halayko AJ, Solway J, Gerthoffer WT. Cyclooxygenase-2 and microRNA-155 expression are elevated in asthmatic airway smooth muscle cells. American Journal of Respiratory Cell and Molecular Biology. 52: 438-47. PMID 25180620 DOI: 10.1165/Rcmb.2014-0129Oc  0.44
2014 Comer BS, Camoretti-Mercado B, Kogut PC, Halayko AJ, Solway J, Gerthoffer WT. MicroRNA-146a and microRNA-146b expression and anti-inflammatory function in human airway smooth muscle. American Journal of Physiology. Lung Cellular and Molecular Physiology. 307: L727-34. PMID 25217662 DOI: 10.1152/Ajplung.00174.2014  0.44
2013 Tran T, Teoh CM, Tam JK, Qiao Y, Chin CY, Chong OK, Stewart AG, Harris T, Wong WS, Guan SP, Leung BP, Gerthoffer WT, Unruh H, Halayko AJ. Laminin drives survival signals to promote a contractile smooth muscle phenotype and airway hyperreactivity. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 3991-4003. PMID 23756649 DOI: 10.1096/Fj.12-221341  0.44
2013 Gerthoffer WT, Solway J, Camoretti-Mercado B. Emerging targets for novel therapy of asthma. Current Opinion in Pharmacology. 13: 324-30. PMID 23639507 DOI: 10.1016/J.Coph.2013.04.002  0.44
2012 Joshi SR, Comer BS, McLendon JM, Gerthoffer WT. MicroRNA Regulation of Smooth Muscle Phenotype. Molecular and Cellular Pharmacology. 4: 1-16. PMID 25309675  0.44
2012 Gerthoffer WT, Schaafsma D, Sharma P, Ghavami S, Halayko AJ. Motility, survival, and proliferation. Comprehensive Physiology. 2: 255-81. PMID 23728975 DOI: 10.1002/Cphy.C110018  0.44
2011 Joshi SR, McLendon JM, Comer BS, Gerthoffer WT. MicroRNAs-control of essential genes: Implications for pulmonary vascular disease. Pulmonary Circulation. 1: 357-64. PMID 22140625 DOI: 10.4103/2045-8932.87301  0.44
2011 Singer CA, Lontay B, Unruh H, Halayko AJ, Gerthoffer WT. Src mediates cytokine-stimulated gene expression in airway myocytes through ERK MAPK. Cell Communication and Signaling : Ccs. 9: 14. PMID 21599982 DOI: 10.1186/1478-811X-9-14  0.44
2011 Milton DL, Schneck AN, Ziech DA, Ba M, Facemyer KC, Halayko AJ, Baker JE, Gerthoffer WT, Cremo CR. Direct evidence for functional smooth muscle myosin II in the 10S self-inhibited monomeric conformation in airway smooth muscle cells. Proceedings of the National Academy of Sciences of the United States of America. 108: 1421-6. PMID 21205888 DOI: 10.1073/Pnas.1011784108  0.44
2011 Gosens R, Stelmack GL, Bos ST, Dueck G, Mutawe MM, Schaafsma D, Unruh H, Gerthoffer WT, Zaagsma J, Meurs H, Halayko AJ. Caveolin-1 is required for contractile phenotype expression by airway smooth muscle cells. Journal of Cellular and Molecular Medicine. 15: 2430-42. PMID 21199324 DOI: 10.1111/J.1582-4934.2010.01246.X  0.44
2010 Dowell ML, Lavoie TL, Lakser OJ, Dulin NO, Fredberg JJ, Gerthoffer WT, Seow CY, Mitchell RW, Solway J. MEK modulates force-fluctuation-induced relengthening of canine tracheal smooth muscle. The European Respiratory Journal. 36: 630-7. PMID 20110395 DOI: 10.1183/09031936.00160209  0.44
2010 Kuhn AR, Schlauch K, Lao R, Halayko AJ, Gerthoffer WT, Singer CA. MicroRNA expression in human airway smooth muscle cells: role of miR-25 in regulation of airway smooth muscle phenotype. American Journal of Respiratory Cell and Molecular Biology. 42: 506-13. PMID 19541842 DOI: 10.1165/Rcmb.2009-0123Oc  0.44
2009 Redhu NS, Saleh A, Shan L, Gerthoffer WT, Kung SK, Halayko AJ, Lamkhioued B, Gounni AS. Proinflammatory and Th2 cytokines regulate the high affinity IgE receptor (FcepsilonRI) and IgE-dependant activation of human airway smooth muscle cells. Plos One. 4: e6153. PMID 19582151 DOI: 10.1371/Journal.Pone.0006153  0.44
2009 Watanabe S, Yamasaki A, Hashimoto K, Shigeoka Y, Chikumi H, Hasegawa Y, Sumikawa T, Takata M, Okazaki R, Watanabe M, Yokogawa T, Yamamura M, Hayabuchi T, Gerthoffer WT, Halayko AJ, et al. Expression of functional leukotriene B4 receptors on human airway smooth muscle cells. The Journal of Allergy and Clinical Immunology. 124: 59-65.e1-3. PMID 19477492 DOI: 10.1016/J.Jaci.2009.03.024  0.44
2009 Lavoie TL, Dowell ML, Lakser OJ, Gerthoffer WT, Fredberg JJ, Seow CY, Mitchell RW, Solway J. Disrupting actin-myosin-actin connectivity in airway smooth muscle as a treatment for asthma? Proceedings of the American Thoracic Society. 6: 295-300. PMID 19387033 DOI: 10.1513/pats.200808-078RM  0.44
2008 Sharma P, Tran T, Stelmack GL, McNeill K, Gosens R, Mutawe MM, Unruh H, Gerthoffer WT, Halayko AJ. Expression of the dystrophin-glycoprotein complex is a marker for human airway smooth muscle phenotype maturation. American Journal of Physiology. Lung Cellular and Molecular Physiology. 294: L57-68. PMID 17993586 DOI: 10.1152/Ajplung.00378.2007  0.44
2007 Gosens R, Stelmack GL, Dueck G, Mutawe MM, Hinton M, McNeill KD, Paulson A, Dakshinamurti S, Gerthoffer WT, Thliveris JA, Unruh H, Zaagsma J, Halayko AJ. Caveolae facilitate muscarinic receptor-mediated intracellular Ca2+ mobilization and contraction in airway smooth muscle. American Journal of Physiology. Lung Cellular and Molecular Physiology. 293: L1406-18. PMID 17890325 DOI: 10.1152/Ajplung.00312.2007  0.44
2007 Gosens R, Dueck G, Rector E, Nunes RO, Gerthoffer WT, Unruh H, Zaagsma J, Meurs H, Halayko AJ. Cooperative regulation of GSK-3 by muscarinic and PDGF receptors is associated with airway myocyte proliferation. American Journal of Physiology. Lung Cellular and Molecular Physiology. 293: L1348-58. PMID 17873004 DOI: 10.1152/Ajplung.00346.2007  0.44
2007 Salinthone S, Ba M, Hanson L, Martin JL, Halayko AJ, Gerthoffer WT. Overexpression of human Hsp27 inhibits serum-induced proliferation in airway smooth muscle myocytes and confers resistance to hydrogen peroxide cytotoxicity. American Journal of Physiology. Lung Cellular and Molecular Physiology. 293: L1194-207. PMID 17720870 DOI: 10.1152/Ajplung.00453.2006  0.44
2007 Tran T, Ens-Blackie K, Rector ES, Stelmack GL, McNeill KD, Tarone G, Gerthoffer WT, Unruh H, Halayko AJ. Laminin-binding integrin alpha7 is required for contractile phenotype expression by human airway myocytes. American Journal of Respiratory Cell and Molecular Biology. 37: 668-80. PMID 17641293 DOI: 10.1165/Rcmb.2007-0165Oc  0.44
2007 An SS, Bai TR, Bates JH, Black JL, Brown RH, Brusasco V, Chitano P, Deng L, Dowell M, Eidelman DH, Fabry B, Fairbank NJ, Ford LE, Fredberg JJ, Gerthoffer WT, et al. Airway smooth muscle dynamics: a common pathway of airway obstruction in asthma. The European Respiratory Journal. 29: 834-60. PMID 17470619 DOI: 10.1183/09031936.00112606  0.44
2007 Gosens R, Dueck G, Gerthoffer WT, Unruh H, Zaagsma J, Meurs H, Halayko AJ. p42/p44 MAP kinase activation is localized to caveolae-free membrane domains in airway smooth muscle. American Journal of Physiology. Lung Cellular and Molecular Physiology. 292: L1163-72. PMID 17237147 DOI: 10.1152/Ajplung.00471.2006  0.44
2006 Tran T, McNeill KD, Gerthoffer WT, Unruh H, Halayko AJ. Endogenous laminin is required for human airway smooth muscle cell maturation. Respiratory Research. 7: 117. PMID 16968549 DOI: 10.1186/1465-9921-7-117  0.44
2006 Gosens R, Stelmack GL, Dueck G, McNeill KD, Yamasaki A, Gerthoffer WT, Unruh H, Gounni AS, Zaagsma J, Halayko AJ. Role of caveolin-1 in p42/p44 MAP kinase activation and proliferation of human airway smooth muscle. American Journal of Physiology. Lung Cellular and Molecular Physiology. 291: L523-34. PMID 16617096 DOI: 10.1152/Ajplung.00013.2006  0.44
2005 Dowell ML, Lakser OJ, Gerthoffer WT, Fredberg JJ, Stelmack GL, Halayko AJ, Solway J, Mitchell RW. Latrunculin B increases force fluctuation-induced relengthening of ACh-contracted, isotonically shortened canine tracheal smooth muscle. Journal of Applied Physiology (Bethesda, Md. : 1985). 98: 489-97. PMID 15465883 DOI: 10.1152/Japplphysiol.01378.2003  0.44
2004 Bai TR, Bates JH, Brusasco V, Camoretti-Mercado B, Chitano P, Deng LH, Dowell M, Fabry B, Ford LE, Fredberg JJ, Gerthoffer WT, Gilbert SH, Gunst SJ, Hai CM, Halayko AJ, et al. On the terminology for describing the length-force relationship and its changes in airway smooth muscle. Journal of Applied Physiology (Bethesda, Md. : 1985). 97: 2029-34. PMID 15531570 DOI: 10.1152/Japplphysiol.00884.2004  0.44
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