William T. Gerthoffer - Related publications

College of Medicine University of South Alabama, Mobile, AL, United States 
Cell Biology, Biochemistry, Molecular Biology
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 Lim JO, Lee SJ, Kim WI, Pak SW, Moon C, Shin IS, Heo JD, Ko JW, Kim JC. Titanium Dioxide Nanoparticles Exacerbate Allergic Airway Inflammation via TXNIP Upregulation in a Mouse Model of Asthma. International Journal of Molecular Sciences. 22. PMID 34576095 DOI: 10.3390/ijms22189924   
2021 Wang Q, Hong L, Chen M, Shi J, Lin X, Huang L, Tang T, Guo Y, Yuan X, Jiang S. Targeting M2 Macrophages Alleviates Airway Inflammation and Remodeling in Asthmatic Mice miR-378a-3p/GRB2 Pathway. Frontiers in Molecular Biosciences. 8: 717969. PMID 34589519 DOI: 10.3389/fmolb.2021.717969   
2021 Smith GJ, Tovar A, Kanke M, Wang Y, Deshane JS, Sethupathy P, Kelada SNP. Ozone-induced changes in the murine lung extracellular vesicle small RNA landscape. Physiological Reports. 9: e15054. PMID 34558223 DOI: 10.14814/phy2.15054   
2021 Senavirathna LK, Liang Y, Huang C, Yang X, Bamunuarachchi G, Xu D, Dang Q, Sivasami P, Vaddadi K, Munteanu MC, Hewawasam S, Cheresh P, Kamp DW, Liu L. Long Noncoding RNA Inhibits Lung Fibroblast Proliferation via a Reduction of β-Catenin. International Journal of Molecular Sciences. 22. PMID 34445242 DOI: 10.3390/ijms22168536   
2021 Chen H, He A, Li H, Chen H, Xie H, Luo L, Huang Y, Chen J, Guan J, He Q, Ma J, Ou C, Tao A, Yan J. TSSK4 upregulation in alveolar epithelial type-II cells facilitates pulmonary fibrosis through HSP90-AKT signaling restriction and AT-II apoptosis. Cell Death & Disease. 12: 938. PMID 34645797 DOI: 10.1038/s41419-021-04232-3   
2021 Zheng J, Zhu S, Xu H, Li J, Tang H, Zhou Y, Huang Z, Liu G. miR-363-3p inhibits rat lung alveolar type II cell proliferation by downregulating expression and induces cell apoptosis via cellular oxidative stress and G1-phase cell cycle arrest. Translational Pediatrics. 10: 2095-2105. PMID 34584880 DOI: 10.21037/tp-21-303   
2021 Zhang XL, An J, Deng YZ, Fang XZ, Xu CY, Liu XF, Bai ZH, Zhang G, Cui MY. A novel miRNA-762/NFIX pathway modulates LPS-induced acute lung injury. International Immunopharmacology. 100: 108066. PMID 34492536 DOI: 10.1016/j.intimp.2021.108066   
2021 Cheng R, Xu H, Hong Y. miR221 regulates TGF-β1-induced HSC activation through inhibiting autophagy by directly targeting LAMP2. Molecular Medicine Reports. 24. PMID 34498712 DOI: 10.3892/mmr.2021.12417   
2021 Liu J, Li S, Fei X, Nan X, Shen Y, Xiu H, Cormier SA, Lu C, Guo C, Wang S, Cai Z, Wang P. Increased alveolar epithelial TRAF6 via autophagy-dependent TRIM37 degradation mediates particulate matter-induced lung metastasis. Autophagy. 1-19. PMID 34524943 DOI: 10.1080/15548627.2021.1965421   
2021 Wang H, Zhong B, Geng Y, Hao J, Jin Q, Zhang Y, Dong L, Gao D, Li J, Hou W. TIPE2 inhibits PDGF-BB-induced phenotype switching in airway smooth muscle cells through the PI3K/Akt signaling pathway. Respiratory Research. 22: 238. PMID 34446024 DOI: 10.1186/s12931-021-01826-5   
2021 Li H, Quan F, Zhang P, Shao Y. Long non-coding RNA SNHG16, binding with miR-106b-5p, promoted cell apoptosis and inflammation in allergic rhinitis by up-regulating leukemia inhibitory factor to activate the JAK1/STAT3 signaling pathway. Human & Experimental Toxicology. 9603271211035665. PMID 34407675 DOI: 10.1177/09603271211035665   
2021 Leal K, Saavedra K, Rebolledo C, Salazar LA. MicroRNAs hsa-miR-618 and hsa-miR-297 Might Modulate the Pleiotropic Effects Exerted by Statins in Endothelial Cells Through the Inhibition of ROCK2 Kinase: Approach. Frontiers in Cardiovascular Medicine. 8: 704175. PMID 34485404 DOI: 10.3389/fcvm.2021.704175   
2021 Zhang Y, Tang J, Li N, Tao J, Zhang Y, Zhang Y, Ye Y, Zheng Q, Xu T, Liu Y, Zhang P, Li L, Li H, He Y, Su H, et al. Prenatal hypoxia induced ETR activation and abnormal ROS signaling in pulmonary arteries and cells of rat offspring. Reproductive Toxicology (Elmsford, N.Y.). PMID 34478853 DOI: 10.1016/j.reprotox.2021.08.009   
2021 Cho HY, Jedlicka AE, Chang FH, Marzec J, Bauer AK, Kleeberger SR. Transcriptomics Underlying Pulmonary Ozone Pathogenesis Regulated by Inflammatory Mediators in Mice. Antioxidants (Basel, Switzerland). 10. PMID 34573120 DOI: 10.3390/antiox10091489   
2021 Wu Q, Gui W, Jiao B, Han L, Wang F. miR-138 inhibits epithelial-mesenchymal transition in silica-induced pulmonary fibrosis by regulating ZEB2. Toxicology. 152925. PMID 34481903 DOI: 10.1016/j.tox.2021.152925   
2021 Xiao K, Song L, Hu Y, He W, Hou F, Yan P, Xu J, Wang K, Tao Y, Li D, Xie L. Novel Role of miR-18a-5p and Galanin in Rat Lung Ischemia Reperfusion-Mediated Response. Oxidative Medicine and Cellular Longevity. 2021: 6621921. PMID 34497682 DOI: 10.1155/2021/6621921   
2021 Li L, Zuo X, Liu D, Luo H, Zhu H. The Functional Roles of RNAs Cargoes Released by Neutrophil-Derived Exosomes in Dermatomyositis. Frontiers in Pharmacology. 12: 727901. PMID 34603043 DOI: 10.3389/fphar.2021.727901   
2021 Chang KW, Zhang X, Lin SC, Lin YC, Li CH, Akhrymuk I, Lin SH, Lin CC. Atractylodin Suppresses TGF-β-Mediated Epithelial-Mesenchymal Transition in Alveolar Epithelial Cells and Attenuates Bleomycin-Induced Pulmonary Fibrosis in Mice. International Journal of Molecular Sciences. 22. PMID 34681813 DOI: 10.3390/ijms222011152   
2021 Lu R, Zhu W, Sun H, Zhang L, Yu Z, Nie Z, Gao Y. Study on the Effect and Mechanism of miR-185 on Lower Extremity Deep Venous Thrombosis. Molecular Biotechnology. PMID 34647243 DOI: 10.1007/s12033-021-00412-w   
2021 Tan W, Wang Y, Chen Y, Chen C. Cell tracing reveals the transdifferentiation fate of mouse lung epithelial cells during pulmonary fibrosis . Experimental and Therapeutic Medicine. 22: 1188. PMID 34475978 DOI: 10.3892/etm.2021.10622   
2021 Hussain MS, Sharma P, Dhanjal DS, Khurana N, Vyas M, Sharma N, Mehta M, Tambuwala MM, Satija S, Sohal SS, Oliver BGG, Sharma HS. Nanotechnology based advanced therapeutic strategies for targeting interleukins in chronic respiratory diseases. Chemico-Biological Interactions. 109637. PMID 34506765 DOI: 10.1016/j.cbi.2021.109637   
2021 Park SJ, Kim TH, Lee K, Kang MA, Jang HJ, Ryu HW, Oh SR, Lee HJ. Kurarinone Attenuates BLM-Induced Pulmonary Fibrosis via Inhibiting TGF-β Signaling Pathways. International Journal of Molecular Sciences. 22. PMID 34445094 DOI: 10.3390/ijms22168388   
2021 Zhang J, Lei H, Li X. LncRNA SNHG14 contributes to proinflammatory cytokine production in rheumatoid arthritis via the regulation of the miR-17-5p/MINK1-JNK pathway. Environmental Toxicology. PMID 34529319 DOI: 10.1002/tox.23361   
2021 Berghausen EM, Janssen W, Vantler M, Gnatzy-Feik LL, Krause M, Behringer A, Joseph C, Zierden M, Freyhaus HT, Klinke A, Baldus S, Alcazar MA, Savai R, Pullamsetti SS, Wong DW, et al. Disrupted PI3K subunit p110α signaling protects against pulmonary hypertension and reverses established disease in rodents. The Journal of Clinical Investigation. 131. PMID 34596056 DOI: 10.1172/JCI136939   
2021 Carmo-Fernandes A, Puschkarow M, Peters K, Gnipp S, Peters M. The Pathogenic Role of Smooth Muscle Cell-Derived Wnt5a in a Murine Model of Lung Fibrosis. Pharmaceuticals (Basel, Switzerland). 14. PMID 34451852 DOI: 10.3390/ph14080755   
2021 Han Y, Ali MK, Dua K, Spiekerkoetter E, Mao Y. Role of Long Non-Coding RNAs in Pulmonary Arterial Hypertension. Cells. 10. PMID 34440661 DOI: 10.3390/cells10081892   
2021 Siques P, Pena E, Brito J, El Alam S. Oxidative Stress, Kinase Activation, and Inflammatory Pathways Involved in Effects on Smooth Muscle Cells During Pulmonary Artery Hypertension Under Hypobaric Hypoxia Exposure. Frontiers in Physiology. 12: 690341. PMID 34434114 DOI: 10.3389/fphys.2021.690341   
2021 Tian Y, Lv J, Su Z, Wu T, Li X, Hu X, Zhang J, Wu L. LRRK2 plays essential roles in maintaining lung homeostasis and preventing the development of pulmonary fibrosis. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34446559 DOI: 10.1073/pnas.2106685118   
2021 Duan JX, Guan XX, Yang HH, Mei WX, Chen P, Tao JH, Li Q, Zhou Y. Vasoactive intestinal peptide attenuates bleomycin-induced murine pulmonary fibrosis by inhibiting epithelial-mesenchymal transition: Restoring autophagy in alveolar epithelial cells. International Immunopharmacology. 101: 108211. PMID 34634687 DOI: 10.1016/j.intimp.2021.108211   
2021 Chu SJ, Tang SE, Pao HP, Wu SY, Liao WI. Protease-Activated Receptor-1 Antagonist Protects Against Lung Ischemia/Reperfusion Injury. Frontiers in Pharmacology. 12: 752507. PMID 34658893 DOI: 10.3389/fphar.2021.752507   
2021 Jeong MH, Kim HR, Park YJ, Chung KH, Kim HS. Reprogrammed lung epithelial cells by decrease of miR-451a in extracellular vesicles contribute to aggravation of pulmonary fibrosis. Cell Biology and Toxicology. PMID 34460027 DOI: 10.1007/s10565-021-09626-9   
2021 Jung S, Lee MS, Chang E, Kim CT, Kim Y. Mulberry ( L.) Fruit Extract Ameliorates Inflammation via Regulating MicroRNA-21/132/143 Expression and Increases the Skeletal Muscle Mitochondrial Content and AMPK/SIRT Activities. Antioxidants (Basel, Switzerland). 10. PMID 34573085 DOI: 10.3390/antiox10091453   
2021 Song J, Jung KJ, Cho JW, Park T, Han SC, Park D. Transcriptomic Analysis of Polyhexamethyleneguanidine-Induced Lung Injury in Mice after a Long-Term Recovery. Toxics. 9. PMID 34678949 DOI: 10.3390/toxics9100253   
2021 Liu Y, Wei L, He C, Chen R, Meng L. Lipoxin A4 inhibits ovalbumin-induced airway inflammation and airway remodeling in a mouse model of asthma. Chemico-Biological Interactions. 109660. PMID 34537180 DOI: 10.1016/j.cbi.2021.109660   
2021 Chen HB, Xu XH, Yu CG, Wan MT, Feng CL, Zhao ZY, Mei DE, Chen JL. Tuberous sclerosis complex-lymphangioleiomyomatosis involving several visceral organs: A case report. World Journal of Clinical Cases. 9: 7085-7091. PMID 34540963 DOI: 10.12998/wjcc.v9.i24.7085   
2021 Kadota T, Fujita Y, Araya J, Watanabe N, Fujimoto S, Kawamoto H, Minagawa S, Hara H, Ohtsuka T, Yamamoto Y, Kuwano K, Ochiya T. Human bronchial epithelial cell-derived extracellular vesicle therapy for pulmonary fibrosis via inhibition of TGF-β-WNT crosstalk. Journal of Extracellular Vesicles. 10: e12124. PMID 34377373 DOI: 10.1002/jev2.12124   
2021 Zhang J, He W, Zheng D, He Q, Tan M, Jin J. Exosomal‑miR‑1184 derived from mesenchymal stem cells alleviates cisplatin‑associated acute kidney injury. Molecular Medicine Reports. 24. PMID 34515319 DOI: 10.3892/mmr.2021.12435   
2021 Yao G, Wang X, Wang Y, Hou Q, Gao R, Wang Y, Teng L, Lin W, Wang Z, Jin Y, Chen J. miR‑4792 regulates inflammatory responses in ‑infected microglia. International Journal of Molecular Medicine. 48. PMID 34498713 DOI: 10.3892/ijmm.2021.5031   
2021 Zeng W, Fu L, Xu H. MicroRNA-206 relieves irradiation-induced neuroinflammation by regulating connexin 43. Experimental and Therapeutic Medicine. 22: 1186. PMID 34475976 DOI: 10.3892/etm.2021.10620   
2021 He J, Xuan X, Jiang M, Li J, Li N, Nie T. Long non-coding RNA SNHG1 relieves microglia activation by downregulating miR-329-3p expression in an model of cerebral infarction. Experimental and Therapeutic Medicine. 22: 1148. PMID 34504593 DOI: 10.3892/etm.2021.10581   
2021 Li Y, Tan J, Miao Y, Zhang Q. MicroRNA in extracellular vesicles regulates inflammation through macrophages under hypoxia. Cell Death Discovery. 7: 285. PMID 34635652 DOI: 10.1038/s41420-021-00670-2   
2021 Ge XY, Zhu TT, Yao MZ, Liu H, Wu Q, Qiao J, Zhang WF, Hu CP. MicroRNA-137 Inhibited Hypoxia-Induced Proliferation of Pulmonary Artery Smooth Muscle Cells by Targeting Calpain-2. Biomed Research International. 2021: 2202888. PMID 34513987 DOI: 10.1155/2021/2202888   
2021 Wu Y, Peng W, Fang M, Wu M, Wu M. MSCs-Derived Extracellular Vesicles Carrying miR-212-5p Alleviate Myocardial Infarction-Induced Cardiac Fibrosis via NLRC5/VEGF/TGF-β1/SMAD Axis. Journal of Cardiovascular Translational Research. PMID 34508321 DOI: 10.1007/s12265-021-10156-2   
2021 Zhuang C, Piao C, Choi M, Ha J, Lee M. Delivery of MiRNA-92a Inhibitor Using RP1-Linked Peptide Elicits Anti-Inflammatory Effects in an Acute Lung Injury Model. Journal of Biomedical Nanotechnology. 17: 1273-1283. PMID 34446131 DOI: 10.1166/jbn.2021.3102   
2021 Kaneshita S, Kida T, Yoshioka M, Nishioka K, Raje M, Sakashita A, Hirano A, Sagawa T, Kasahara A, Inoue T, Fujioka K, Nagahara H, Wada M, Kohno M, Strovel JW, et al. CG223, a novel BET inhibitor, exerts TGF-β1-mediated antifibrotic effects in a murine model of bleomycin-induced pulmonary fibrosis. Pulmonary Pharmacology & Therapeutics. 102057. PMID 34425215 DOI: 10.1016/j.pupt.2021.102057   
2021 Wu N, Li Z, Wang J, Geng L, Yue Y, Deng Z, Wang Q, Zhang Q. Low molecular weight fucoidan attenuating pulmonary fibrosis by relieving inflammatory reaction and progression of epithelial-mesenchymal transition. Carbohydrate Polymers. 273: 118567. PMID 34560978 DOI: 10.1016/j.carbpol.2021.118567   
2021 Wang Y, Mou Q, Zhu Z, Zhao L, Zhu L. MALAT1 promotes liver fibrosis by sponging miR‑181a and activating TLR4‑NF‑κB signaling. International Journal of Molecular Medicine. 48. PMID 34651657 DOI: 10.3892/ijmm.2021.5048   
2021 Min JH, Kim SM, Park JW, Kwon NH, Goo SH, Ngatinem, Ningsih S, Paik JH, Choi S, Oh SR, Han SB, Ahn KS, Lee JW. Exerts Anti-inflammatory Effects in Mice of LPS-induced ALI via downregulating of MAPK and NF-κB activation. Journal of Microbiology and Biotechnology. 31. PMID 34489373 DOI: 10.4014/jmb.2107.07023   
2021 Sun W, Byon CH, Kim DH, Choi HI, Park JS, Joo SY, Kim IJ, Jung I, Bae EH, Ma SK, Kim SW. Renoprotective Effects of Maslinic Acid on Experimental Renal Fibrosis in Unilateral Ureteral Obstruction Model via Targeting MyD88. Frontiers in Pharmacology. 12: 708575. PMID 34588982 DOI: 10.3389/fphar.2021.708575   
2021 Wang S, Tan Y, Yang T, Liu C, Li R. Pulmonary AngII promotes LPS-induced lung inflammation by regulating microRNA-143. Cytotechnology. 1-10. PMID 34493899 DOI: 10.1007/s10616-021-00493-0