Emily Bernstein - Publications

Cancer Biology Icahn School of Medicine at Mount Sinai, New York, NY, United States 
Biochemistry, Molecular Biology, Human Development

52 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Mzoughi S, Fong JY, Papadopoli D, Koh CM, Hulea L, Pigini P, Di Tullio F, Andreacchio G, Hoppe MM, Wollmann H, Low D, Caldez MJ, Peng Y, Torre D, Zhao JN, ... ... Bernstein E, et al. PRDM15 is a key regulator of metabolism critical to sustain B-cell lymphomagenesis. Nature Communications. 11: 3520. PMID 32665551 DOI: 10.1038/S41467-020-17064-0  0.4
2019 Qadeer ZA, Valle-Garcia D, Hasson D, Sun Z, Cook A, Nguyen C, Soriano A, Ma A, Griffiths LM, Zeineldin M, Filipescu D, Jubierre L, Chowdhury A, Deevy O, Chen X, ... ... Bernstein E, et al. ATRX In-Frame Fusion Neuroblastoma Is Sensitive to EZH2 Inhibition via Modulation of Neuronal Gene Signatures. Cancer Cell. PMID 31631027 DOI: 10.1016/J.Ccell.2019.09.002  0.4
2019 Wang S, Zhang C, Hasson D, Desai A, SenBanerjee S, Magnani E, Ukomadu C, Lujambio A, Bernstein E, Sadler KC. Epigenetic Compensation Promotes Liver Regeneration. Developmental Cell. PMID 31231040 DOI: 10.1016/J.Devcel.2019.05.034  0.4
2019 Steinbach N, Hasson D, Mathur D, Stratikopoulos EE, Sachidanandam R, Bernstein E, Parsons RE. PTEN interacts with the transcription machinery on chromatin and regulates RNA polymerase II-mediated transcription. Nucleic Acids Research. PMID 31169889 DOI: 10.1093/Nar/Gkz272  0.4
2019 Qadeer Z, Valle-Garcia D, Hasson D, Soriano A, Ma A, Griffiths L, Zeineldin M, Sun Z, Jubierre L, Filipescu D, Chowdhury A, Deevy O, Chen X, Finkelstein D, Bahrami A, ... ... Bernstein E, et al. Gene-05. Atrx In-Frame Fusion Neuroblastoma Is Sensitive To Ezh2 Inhibition Via Modulation Of Neuronal Gene Signatures Neuro-Oncology. 21. DOI: 10.1093/Neuonc/Noz036.076  0.4
2018 Strub T, Ghiraldini FG, Carcamo S, Li M, Wroblewska A, Singh R, Goldberg MS, Hasson D, Wang Z, Gallagher SJ, Hersey P, Ma'ayan A, Long GV, Scolyer RA, Brown B, ... ... Bernstein E, et al. SIRT6 haploinsufficiency induces BRAF melanoma cell resistance to MAPK inhibitors via IGF signalling. Nature Communications. 9: 3440. PMID 30143629 DOI: 10.1038/S41467-018-05966-Z  0.44
2018 Alonso A, Bernstein E, Hasson D. Histone Native Chromatin Immunoprecipitation. Methods in Molecular Biology (Clifton, N.J.). 1832: 77-104. PMID 30073523 DOI: 10.1007/978-1-4939-8663-7_5  0.4
2018 Giricz O, Mo Y, Dahlman KB, Cotto-Rios XM, Vardabasso C, Nguyen H, Matusow B, Bartenstein M, Polishchuk V, Johnson DB, Bhagat TD, Shellooe R, Burton E, Tsai J, Zhang C, ... ... Bernstein E, et al. The RUNX1/IL-34/CSF-1R axis is an autocrinally regulated modulator of resistance to BRAF-V600E inhibition in melanoma. Jci Insight. 3. PMID 30046005 DOI: 10.1172/Jci.Insight.120422  0.36
2018 Giricz O, Mo Y, Dahlman KB, Cotto-Rios XM, Vardabasso C, Nguyen H, Matusow B, Bartenstein M, Polishchuck-Lee V, Johnson DB, Bhagat TB, Shellooe R, Burton E, Habets G, Greally JM, ... ... Bernstein E, et al. Abstract 2515: Aberrant expression of CSF1R in melanoma is driven through an endogenous viral promoter and it contributes to malignant growth and BRAF-inhibitor resistance Cancer Research. 78: 2515-2515. DOI: 10.1158/1538-7445.Am2018-2515  0.36
2017 Fontanals-Cirera B, Hasson D, Vardabasso C, Di Micco R, Agrawal P, Chowdhury A, Gantz M, de Pablos-Aragoneses A, Morgenstern A, Wu P, Filipescu D, Valle-Garcia D, Darvishian F, Roe JS, Davies MA, ... ... Bernstein E, et al. Harnessing BET Inhibitor Sensitivity Reveals AMIGO2 as a Melanoma Survival Gene. Molecular Cell. 68: 731-744.e9. PMID 29149598 DOI: 10.1016/J.Molcel.2017.11.004  0.4
2017 Pünzeler S, Link S, Wagner G, Keilhauer EC, Kronbeck N, Spitzer RM, Leidescher S, Markaki Y, Mentele E, Regnard C, Schneider K, Takahashi D, Kusakabe M, Vardabasso C, Zink LM, ... ... Bernstein E, et al. Multivalent binding of PWWP2A to H2A.Z regulates mitosis and neural crest differentiation. The Embo Journal. PMID 28645917 DOI: 10.15252/Embj.201695757  0.36
2016 Vardabasso C, Bernstein E. Can histone proteins promote the growth of melanoma? Melanoma Management. 3: 1-4. PMID 30190866 DOI: 10.2217/Mmt.15.35  0.36
2016 Chung CY, Sun Z, Mullokandov G, Bosch A, Qadeer ZA, Cihan E, Rapp Z, Parsons R, Aguirre-Ghiso JA, Farias EF, Brown BD, Gaspar-Maia A, Bernstein E. Cbx8 Acts Non-canonically with Wdr5 to Promote Mammary Tumorigenesis. Cell Reports. PMID 27346354 DOI: 10.1016/J.Celrep.2016.06.002  0.36
2016 Vardabasso C, Hake SB, Bernstein E. Histone variant H2A.Z.2: A novel driver of melanoma progression. Molecular & Cellular Oncology. 3: e1073417. PMID 27308593 DOI: 10.1080/23723556.2015.1073417  0.36
2016 Valle-García D, Qadeer ZA, McHugh DS, Ghiraldini FG, Chowdhury AH, Hasson D, Dyer MA, Recillas-Targa F, Bernstein E. ATRX binds to atypical chromatin domains at the 3' exons of zinc finger genes to preserve H3K9me3 enrichment. Epigenetics. 0. PMID 27029610 DOI: 10.1080/15592294.2016.1169351  0.52
2015 Bansal N, Petrie K, Christova R, Chung CY, Leibovitch BA, Howell L, Gil V, Sbirkov Y, Lee E, Wexler J, Ariztia EV, Sharma R, Zhu J, Bernstein E, Zhou MM, et al. Targeting the SIN3A-PF1 interaction inhibits epithelial to mesenchymal transition and maintenance of a stem cell phenotype in triple negative breast cancer. Oncotarget. PMID 26460951 DOI: 10.18632/Oncotarget.6048  0.52
2015 Vardabasso C, Gaspar-Maia A, Hasson D, Pünzeler S, Valle-Garcia D, Straub T, Keilhauer EC, Strub T, Dong J, Panda T, Chung CY, Yao JL, Singh R, Segura MF, Fontanals-Cirera B, ... ... Bernstein E, et al. Histone Variant H2A.Z.2 Mediates Proliferation and Drug Sensitivity of Malignant Melanoma. Molecular Cell. 59: 75-88. PMID 26051178 DOI: 10.1016/J.Molcel.2015.05.009  0.52
2015 Sosa MS, Parikh F, Maia AG, Estrada Y, Bosch A, Bragado P, Ekpin E, George A, Zheng Y, Lam HM, Morrissey C, Chung CY, Farias EF, Bernstein E, Aguirre-Ghiso JA. NR2F1 controls tumour cell dormancy via SOX9- and RARβ-driven quiescence programmes. Nature Communications. 6: 6170. PMID 25636082 DOI: 10.1038/Ncomms7170  0.52
2015 Vardabasso C, Gaspar-Maia A, Punzeler S, Valle-Garcia D, Hasson D, Straub T, Keilhauer EC, Strub T, Panda T, Segura MF, Chung C, Verma AK, Mann M, Hernando E, Hake SB, ... Bernstein E, et al. Abstract A12: Histone variant H2A.Z.2 mediates proliferation and drug sensitivity of malignant melanoma Cancer Research. 75. DOI: 10.1158/1538-7445.Mel2014-A12  0.44
2015 Duarte LF, Young ARJ, Wang Z, Wu H, Panda T, Kou Y, Kapoor A, Hasson D, Mills NR, Ma'ayan A, Narita M, Bernstein E. Abstract SY10-04: Histone tail alterations in cellular senescence Cancer Research. 75. DOI: 10.1158/1538-7445.Am2015-Sy10-04  0.44
2014 Duarte LF, Young AR, Wang Z, Wu HA, Panda T, Kou Y, Kapoor A, Hasson D, Mills NR, Ma'ayan A, Narita M, Bernstein E. Histone H3.3 and its proteolytically processed form drive a cellular senescence programme. Nature Communications. 5: 5210. PMID 25394905 DOI: 10.1038/Ncomms6210  0.52
2014 Valle-García D, Griffiths LM, Dyer MA, Bernstein E, Recillas-Targa F. The ATRX cDNA is prone to bacterial IS10 element insertions that alter its structure. Springerplus. 3: 222. PMID 24834375 DOI: 10.1186/2193-1801-3-222  0.52
2014 Qadeer ZA, Harcharik S, Valle-Garcia D, Chen C, Birge MB, Vardabasso C, Duarte LF, Bernstein E. Decreased expression of the chromatin remodeler ATRX associates with melanoma progression Journal of Investigative Dermatology. 134: 1768-1772. PMID 24468746 DOI: 10.1038/Jid.2014.45  0.52
2014 Vardabasso C, Hasson D, Ratnakumar K, Chung CY, Duarte LF, Bernstein E. Histone variants: emerging players in cancer biology. Cellular and Molecular Life Sciences : Cmls. 71: 379-404. PMID 23652611 DOI: 10.1007/S00018-013-1343-Z  0.52
2014 Duarte LF, Young AR, Wu H, Panda T, Wang Z, Maia AG, Hasson D, Kapoor A, Narita M, Bernstein E. Abstract 2247: Histone H3 cleavage via Cathepsin L drives a cellular senescence program Cancer Research. 74: 2247-2247. DOI: 10.1158/1538-7445.Am2014-2247  0.44
2013 Wu HA, Balsbaugh JL, Chandler H, Georgilis A, Zullow H, Shabanowitz J, Hunt DF, Gil J, Peters G, Bernstein E. Mitogen-activated protein kinase signaling mediates phosphorylation of polycomb ortholog Cbx7. The Journal of Biological Chemistry. 288: 36398-408. PMID 24194518 DOI: 10.1074/Jbc.M113.486266  0.52
2013 Mungamuri SK, Murk W, Grumolato L, Bernstein E, Aaronson SA. Chromatin modifications sequentially enhance ErbB2 expression in ErbB2-positive breast cancers. Cell Reports. 5: 302-13. PMID 24120871 DOI: 10.1016/J.Celrep.2013.09.009  0.52
2013 Gaspar-Maia A, Qadeer ZA, Hasson D, Ratnakumar K, Leu NA, Leroy G, Liu S, Costanzi C, Valle-Garcia D, Schaniel C, Lemischka I, Garcia B, Pehrson JR, Bernstein E. MacroH2A histone variants act as a barrier upon reprogramming towards pluripotency. Nature Communications. 4: 1565. PMID 23463008 DOI: 10.1038/Ncomms2582  0.52
2013 Ratnakumar K, Bernstein E. ATRX: the case of a peculiar chromatin remodeler. Epigenetics. 8: 3-9. PMID 23249563 DOI: 10.4161/Epi.23271  1
2013 Chung C, Gaspar-Maia A, Mullokandov G, Bosch-Gutierrez A, Farias E, Brown B, Bernstein E. Abstract A021: Loss-of-function screen for breast tumor initiating cells reveals PRC1 dependence Molecular Cancer Research. 11. DOI: 10.1158/1557-3125.Advbc-A021  0.32
2013 Gaspar-Maia A, Qadeer ZA, Hasson D, Ratnakumar K, Leu NA, Leroy G, Liu S, Costanzi C, Valle-Garcia D, Schaniel C, Lemischka I, Garcia B, Pehrson JR, Bernstein E. MacroH2A histone variants act as a barrier upon reprogramming towards pluripotency (Nature Communications (2013) 4, (1565) DOI: 10.1038/ncomms2582) Nature Communications. 4. DOI: 10.1038/Ncomms3090  0.52
2012 Chicas A, Kapoor A, Wang X, Aksoy O, Evertts AG, Zhang MQ, Garcia BA, Bernstein E, Lowe SW. H3K4 demethylation by Jarid1a and Jarid1b contributes to retinoblastoma-mediated gene silencing during cellular senescence. Proceedings of the National Academy of Sciences of the United States of America. 109: 8971-6. PMID 22615382 DOI: 10.1073/Pnas.1119836109  0.52
2012 Ratnakumar K, Duarte LF, LeRoy G, Hasson D, Smeets D, Vardabasso C, Bönisch C, Zeng T, Xiang B, Zhang DY, Li H, Wang X, Hake SB, Schermelleh L, Garcia BA, ... Bernstein E, et al. ATRX-mediated chromatin association of histone variant macroH2A1 regulates α-globin expression. Genes & Development. 26: 433-8. PMID 22391447 DOI: 10.1101/Gad.179416.111  0.52
2012 Bragado P, Estrada Y, Sosa MS, Avivar-Valderas A, Cannan D, Genden E, Teng M, Ranganathan AC, Wen HC, Kapoor A, Bernstein E, Aguirre-Ghiso JA. Analysis of marker-defined HNSCC subpopulations reveals a dynamic regulation of tumor initiating properties. Plos One. 7: e29974. PMID 22276135 DOI: 10.1371/Journal.Pone.0029974  0.52
2012 O'Loghlen A, Muñoz-Cabello AM, Gaspar-Maia A, Wu HA, Banito A, Kunowska N, Racek T, Pemberton HN, Beolchi P, Lavial F, Masui O, Vermeulen M, Carroll T, Graumann J, Heard E, ... ... Bernstein E, et al. MicroRNA regulation of Cbx7 mediates a switch of Polycomb orthologs during ESC differentiation. Cell Stem Cell. 10: 33-46. PMID 22226354 DOI: 10.1016/J.Stem.2011.12.004  0.52
2011 Ang YS, Gaspar-Maia A, Lemischka IR, Bernstein E. Stem cells and reprogramming: breaking the epigenetic barrier? Trends in Pharmacological Sciences. 32: 394-401. PMID 21621281 DOI: 10.1016/J.Tips.2011.03.002  0.52
2011 Ang YS, Tsai SY, Lee DF, Monk J, Su J, Ratnakumar K, Ding J, Ge Y, Darr H, Chang B, Wang J, Rendl M, Bernstein E, Schaniel C, Lemischka IR. Wdr5 mediates self-renewal and reprogramming via the embryonic stem cell core transcriptional network. Cell. 145: 183-97. PMID 21477851 DOI: 10.1016/J.Cell.2011.03.003  0.52
2010 Kapoor A, Goldberg MS, Cumberland LK, Ratnakumar K, Segura MF, Emanuel PO, Menendez S, Vardabasso C, Leroy G, Vidal CI, Polsky D, Osman I, Garcia BA, Hernando E, Bernstein E. The histone variant macroH2A suppresses melanoma progression through regulation of CDK8. Nature. 468: 1105-9. PMID 21179167 DOI: 10.1038/Nature09590  1
2009 Schaniel C, Ang YS, Ratnakumar K, Cormier C, James T, Bernstein E, Lemischka IR, Paddison PJ. Smarcc1/Baf155 couples self-renewal gene repression with changes in chromatin structure in mouse embryonic stem cells. Stem Cells (Dayton, Ohio). 27: 2979-91. PMID 19785031 DOI: 10.1002/Stem.223  0.52
2008 Wu HA, Bernstein E. Partners in imprinting: noncoding RNA and polycomb group proteins. Developmental Cell. 15: 637-8. PMID 19000827 DOI: 10.1016/J.Devcel.2008.10.008  0.68
2008 Bernstein E, Muratore-Schroeder TL, Diaz RL, Chow JC, Changolkar LN, Shabanowitz J, Heard E, Pehrson JR, Hunt DF, Allis CD. A phosphorylated subpopulation of the histone variant macroH2A1 is excluded from the inactive X chromosome and enriched during mitosis. Proceedings of the National Academy of Sciences of the United States of America. 105: 1533-8. PMID 18227505 DOI: 10.1073/Pnas.0711632105  0.52
2007 Whitcomb SJ, Basu A, Allis CD, Bernstein E. Polycomb Group proteins: an evolutionary perspective. Trends in Genetics : Tig. 23: 494-502. PMID 17825942 DOI: 10.1016/J.Tig.2007.08.006  0.52
2007 Ooi SK, Qiu C, Bernstein E, Li K, Jia D, Yang Z, Erdjument-Bromage H, Tempst P, Lin SP, Allis CD, Cheng X, Bestor TH. DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA. Nature. 448: 714-7. PMID 17687327 DOI: 10.1038/Nature05987  0.52
2007 Goldberg AD, Allis CD, Bernstein E. Epigenetics: a landscape takes shape. Cell. 128: 635-8. PMID 17320500 DOI: 10.1016/J.Cell.2007.02.006  0.52
2006 Bernstein E, Duncan EM, Masui O, Gil J, Heard E, Allis CD. Mouse polycomb proteins bind differentially to methylated histone H3 and RNA and are enriched in facultative heterochromatin Molecular and Cellular Biology. 26: 2560-2569. PMID 16537902 DOI: 10.1128/Mcb.26.7.2560-2569.2006  0.52
2005 Bernstein E, Allis CD. RNA meets chromatin Genes and Development. 19: 1635-1655. PMID 16024654 DOI: 10.1101/Gad.1324305  0.52
2004 Svoboda P, Stein P, Anger M, Bernstein E, Hannon GJ, Schultz RM. RNAi and expression of retrotransposons MuERV-L and IAP in preimplantation mouse embryos. Developmental Biology. 269: 276-85. PMID 15081373 DOI: 10.1016/J.Ydbio.2004.01.028  0.52
2003 Bernstein E, Kim SY, Carmell MA, Murchison EP, Alcorn H, Li MZ, Mills AA, Elledge SJ, Anderson KV, Hannon GJ. Dicer is essential for mouse development. Nature Genetics. 35: 215-7. PMID 14528307 DOI: 10.1038/Ng1253  0.52
2002 Paddison PJ, Caudy AA, Bernstein E, Hannon GJ, Conklin DS. Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells. Genes & Development. 16: 948-58. PMID 11959843 DOI: 10.1101/Gad.981002  0.52
2001 Bernstein E, Denli AM, Hannon GJ. The rest is silence. Rna (New York, N.Y.). 7: 1509-21. PMID 11720281  0.52
2001 Bernstein E, Caudy AA, Hammond SM, Hannon GJ. Role for a bidentate ribonuclease in the initiation step of RNA interference Nature. 409: 363-366. PMID 11201747 DOI: 10.1038/35053110  0.52
2000 Hammond SM, Bernstein E, Beach D, Hannon GJ. An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells Nature. 404: 293-296. PMID 10749213 DOI: 10.1038/35005107  0.52
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