Raymond M. Reilly - Publications

Affiliations: 
Pharmaceutical Sciences University of Toronto, Toronto, ON, Canada 
Area:
Pharmacy, Nanotechnology, Oncology, Women's Studies, Biochemistry, Biomedical Engineering

68 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Ku A, Chan C, Aghevlian S, Cai Z, Cescon D, Bratman SV, Ailles L, Hedley DW, Reilly RM. MicroSPECT/CT Imaging of Cell-Line and Patient-Derived EGFR-Positive Tumor Xenografts in Mice with Panitumumab Fab Modified with Hexahistidine Peptides to Enable Labeling with 99mTc (I) Tricarbonyl Complex. Molecular Pharmaceutics. PMID 31242384 DOI: 10.1021/acs.molpharmaceut.9b00422  0.52
2018 Aghevlian S, Cai Z, Lu Y, Hedley DW, Winnik MA, Reilly RM. Radioimmunotherapy of PANC-1 Human Pancreatic Cancer Xenografts in NRG Mice with Panitumumab Modified with Metal-Chelating Polymers (MCP) Complexed to 177Lu. Molecular Pharmaceutics. PMID 30589553 DOI: 10.1021/acs.molpharmaceut.8b01040  0.52
2018 Al-Saden N, Cai Z, Reilly RM. Tumor uptake and tumor/blood ratios for Zr-DFO-trastuzumab-DM1 on microPET/CT images in NOD/SCID mice with human breast cancer xenografts are directly correlated with HER2 expression and response to trastuzumab-DM1. Nuclear Medicine and Biology. 67: 43-51. PMID 30390575 DOI: 10.1016/j.nucmedbio.2018.10.002  0.52
2017 Lai P, Cai Z, Pignol JP, Lechtman E, Mashouf S, Lu Y, Winnik MA, Jaffray DA, Reilly RM. Monte Carlo simulation of radiation transport and dose deposition from locally released gold nanoparticles labeled with (111)In, (177)Lu or (90)Y incorporated into tissue implantable depots. Physics in Medicine and Biology. 62: 8581-8599. PMID 29077574 DOI: 10.1088/1361-6560/aa9106  0.52
2017 Lai P, Cai Z, Pignol JP, Lechtman E, Mashouf S, Lu Y, Winnik MA, Jaffray DA, Reilly RM. Monte Carlo simulation of radiation transport and dose deposition from locally released gold nanoparticles labeled with 111In, 177Lu or 90Y incorporated into tissue implantable depots. Physics in Medicine and Biology. PMID 28976913 DOI: 10.1088/1361-6560/aa9106  0.52
2016 Cai Z, Yook S, Lu Y, Bergstrom D, Winnik MA, Pignol JP, Reilly RM. Local Radiation Treatment of HER2-Positive Breast Cancer Using Trastuzumab-Modified Gold Nanoparticles Labeled with (177)Lu. Pharmaceutical Research. PMID 27987070 DOI: 10.1007/s11095-016-2082-2  0.52
2016 Lai P, Letchman E, Mashouf S, Pignol JP, Reilly RM. Depot system for controlled release of gold nanoparticles with precise intratumoral placement by permanent brachytherapy seed implantation (PSI) techniques. International Journal of Pharmaceutics. PMID 27818245 DOI: 10.1016/j.ijpharm.2016.11.001  0.52
2016 Cai Z, Chattopadhyay N, Yang K, Kwon YL, Yook S, Pignol JP, Reilly RM. (111)In-labeled trastuzumab-modified gold nanoparticles are cytotoxic in vitro to HER2-positive breast cancer cells and arrest tumor growth in vivo in athymic mice after intratumoral injection. Nuclear Medicine and Biology. 43: 818-826. PMID 27788375 DOI: 10.1016/j.nucmedbio.2016.08.009  0.52
2016 Cai Z, Kwon LY, Reilly RM. Monte-Carlo N-Particle (MCNP) Modeling of the Cellular Dosimetry of 64Cu - Comparison with MIRDcell S-Values and Implications for Studies of its Cytotoxic Effects. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 27660146 DOI: 10.2967/jnumed.116.175695  0.52
2016 Bergstrom D, Leyton JV, Zereshkian A, Chan C, Cai Z, Reilly RM. Paradoxical effects of Auger electron-emitting (111)In-DTPA-NLS-CSL360 radioimmunoconjugates on hCD45(+) cells in the bone marrow and spleen of leukemia-engrafted NOD/SCID or NRG mice. Nuclear Medicine and Biology. 43: 635-641. PMID 27497632 DOI: 10.1016/j.nucmedbio.2016.07.006  0.52
2016 Yook S, Lu Y, Jeong JJ, Cai Z, Tong L, Alwarda R, Pignol JP, Winnik MA, Reilly RM. Stability and Biodistribution of Thiol-Functionalized and (177)Lu-Labeled Metal Chelating Polymers Bound to Gold Nanoparticles. Biomacromolecules. 17: 1292-302. PMID 26974228 DOI: 10.1021/acs.biomac.5b01642  0.52
2016 Yook S, Cai Z, Lu Y, Winnik MA, Pignol JP, Reilly RM. Intratumorally Injected 177Lu-Labeled Gold Nanoparticles - Gold Nanoseed Brachytherapy with Application for Neo-Adjuvant Treatment of Locally Advanced Breast Cancer (LABC). Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 26848176 DOI: 10.2967/jnumed.115.168906  0.52
2015 Gao C, Leyton JV, Schimmer AD, Minden M, Reilly RM. Auger electron-emitting (111)In-DTPA-NLS-CSL360 radioimmunoconjugates are cytotoxic to human acute myeloid leukemia (AML) cells displaying the CD123(+)/CD131(-) phenotype of leukemia stem cells. Applied Radiation and Isotopes : Including Data, Instrumentation and Methods For Use in Agriculture, Industry and Medicine. 110: 1-7. PMID 26748017 DOI: 10.1016/j.apradiso.2015.12.043  0.52
2015 Leyton JV, Gao C, Williams B, Keating A, Minden M, Reilly RM. A radiolabeled antibody targeting CD123(+) leukemia stem cells - initial radioimmunotherapy studies in NOD/SCID mice engrafted with primary human AML. Leukemia Research Reports. 4: 55-9. PMID 26500848 DOI: 10.1016/j.lrr.2015.07.003  0.52
2015 Liu P, Boyle AJ, Lu Y, Adams J, Chi Y, Reilly RM, Winnik MA. Metal-Chelating Polymers (MCPs) with Zwitterionic Pendant Groups Complexed to Trastuzumab Exhibit Decreased Liver Accumulation Compared to Polyanionic MCP Immunoconjugates. Biomacromolecules. 16: 3613-23. PMID 26469142 DOI: 10.1021/acs.biomac.5b01066  0.52
2015 Razumienko EJ, Chen JC, Cai Z, Chan C, Reilly RM. Dual Receptor-Targeted Radioimmunotherapy of Human Breast Cancer Xenografts in Athymic Mice Co-Expressing HER2 and EGFR using 177Lu- or 111In-Labeled Bispecific Radioimmunoconjugates. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 26429962 DOI: 10.2967/jnumed.115.162339  0.52
2015 Spence T, De Souza R, Dou Y, Stapleton S, Reilly RM, Allen C. Integration of imaging into clinical practice to assess the delivery and performance of macromolecular and nanotechnology-based oncology therapies. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 26403800 DOI: 10.1016/j.jconrel.2015.09.036  0.52
2015 Yook S, Cai Z, Lu Y, Winnik MA, Pignol JP, Reilly RM. Radiation Nanomedicine for EGFR-Positive Breast Cancer: Panitumumab-Modified Gold Nanoparticles Complexed to the β-Particle-Emitter, (177)Lu. Molecular Pharmaceutics. 12: 3963-72. PMID 26402157 DOI: 10.1021/acs.molpharmaceut.5b00425  0.52
2015 Panosa C, Fonge H, Ferrer-Batallé M, Menéndez JA, Massaguer A, De Llorens R, Reilly RM. A comparison of non-biologically active truncated EGF (EGFt) and full-length hEGF for delivery of Auger electron-emitting (111)In to EGFR-positive breast cancer cells and tumor xenografts in athymic mice. Nuclear Medicine and Biology. PMID 26385534 DOI: 10.1016/j.nucmedbio.2015.08.003  0.4
2015 Ngo Ndjock Mbong G, Lu Y, Chan C, Cai Z, Liu P, Boyle AJ, Winnik MA, Reilly RM. Trastuzumab Labeled to High Specific Activity with (111)In by Site-Specific Conjugation to a Metal-Chelating Polymer Exhibits Amplified Auger Electron-Mediated Cytotoxicity on HER2-Positive Breast Cancer Cells. Molecular Pharmaceutics. 12: 1951-60. PMID 25919639 DOI: 10.1021/mp5007618  0.52
2015 Reilly RM, Lam K, Chan C, Levine M. Advancing novel molecular imaging agents from preclinical studies to first-in-humans phase I clinical trials in academia--a roadmap for overcoming perceived barriers. Bioconjugate Chemistry. 26: 625-32. PMID 25781873 DOI: 10.1021/acs.bioconjchem.5b00105  0.52
2015 Lam K, Chan C, Done SJ, Levine MN, Reilly RM. Preclinical pharmacokinetics, biodistribution, radiation dosimetry and acute toxicity studies required for regulatory approval of a Clinical Trial Application for a Phase I/II clinical trial of (111)In-BzDTPA-pertuzumab. Nuclear Medicine and Biology. 42: 78-84. PMID 25459109 DOI: 10.1016/j.nucmedbio.2014.09.011  0.52
2015 Boyle AJ, Cao PJ, Hedley DW, Sidhu SS, Winnik MA, Reilly RM. MicroPET/CT imaging of patient-derived pancreatic cancer xenografts implanted subcutaneously or orthotopically in NOD-scid mice using (64)Cu-NOTA-panitumumab F(ab')2 fragments. Nuclear Medicine and Biology. 42: 71-7. PMID 25456837 DOI: 10.1016/j.nucmedbio.2014.10.009  0.52
2014 Lam K, Scollard DA, Chan C, Levine MN, Reilly RM. Kit for the preparation of (111)In-labeled pertuzumab injection for imaging response of HER2-positive breast cancer to trastuzumab (Herceptin). Applied Radiation and Isotopes : Including Data, Instrumentation and Methods For Use in Agriculture, Industry and Medicine. 95: 135-142. PMID 25464190 DOI: 10.1016/j.apradiso.2014.10.011  0.52
2014 Leyton JV, Williams B, Gao C, Keating A, Minden M, Reilly RM. MicroSPECT/CT imaging of primary human AML engrafted into the bone marrow and spleen of NOD/SCID mice using 111In-DTPA-NLS-CSL360 radioimmunoconjugates recognizing the CD123+ / CD131- epitope expressed by leukemia stem cells. Leukemia Research. 38: 1367-73. PMID 25278187 DOI: 10.1016/j.leukres.2014.09.005  0.52
2014 Lu Y, Ngo Ndjock Mbong G, Liu P, Chan C, Cai Z, Weinrich D, Boyle AJ, Reilly RM, Winnik MA. Synthesis of polyglutamide-based metal-chelating polymers and their site-specific conjugation to trastuzumab for auger electron radioimmunotherapy. Biomacromolecules. 15: 2027-37. PMID 24838009 DOI: 10.1021/bm500174p  0.52
2014 Vallis KA, Reilly RM, Scollard D, Merante P, Brade A, Velauthapillai S, Caldwell C, Chan I, Freeman M, Lockwood G, Miller NA, Cornelissen B, Petronis J, Sabate K. Phase I trial to evaluate the tumor and normal tissue uptake, radiation dosimetry and safety of (111)In-DTPA-human epidermal growth factor in patients with metastatic EGFR-positive breast cancer. American Journal of Nuclear Medicine and Molecular Imaging. 4: 181-92. PMID 24753984  0.4
2014 Zereshkian A, Leyton JV, Cai Z, Bergstrom D, Weinfeld M, Reilly RM. The human polynucleotide kinase/phosphatase (hPNKP) inhibitor A12B4C3 radiosensitizes human myeloid leukemia cells to Auger electron-emitting anti-CD123 ¹¹¹In-NLS-7G3 radioimmunoconjugates. Nuclear Medicine and Biology. 41: 377-83. PMID 24637100 DOI: 10.1016/j.nucmedbio.2014.02.003  0.52
2014 Liu P, Cai Z, Kang JW, Boyle AJ, Adams J, Lu Y, Ngo Ndjock Mbong G, Sidhu S, Reilly RM, Winnik MA. Intracellular routing in breast cancer cells of streptavidin-conjugated trastuzumab Fab fragments linked to biotinylated doxorubicin-functionalized metal chelating polymers. Biomacromolecules. 15: 715-25. PMID 24506198 DOI: 10.1021/bm401483a  0.52
2013 Cai Z, Pignol JP, Chattopadhyay N, Kwon YL, Lechtman E, Reilly RM. Investigation of the effects of cell model and subcellular location of gold nanoparticles on nuclear dose enhancement factors using Monte Carlo simulation. Medical Physics. 40: 114101. PMID 24320476 DOI: 10.1118/1.4823787  0.52
2013 Panosa C, Tebar F, Ferrer-Batallé M, Fonge H, Seno M, Reilly RM, Massaguer A, De Llorens R. Development of an epidermal growth factor derivative with EGFR blocking activity. Plos One. 8: e69325. PMID 23935985 DOI: 10.1371/journal.pone.0069325  0.4
2013 Banerjee N, Fonge H, Mikhail A, Reilly RM, Bendayan R, Allen C. Estrone-3-sulphate, a potential novel ligand for targeting breast cancers. Plos One. 8: e64069. PMID 23717534 DOI: 10.1371/journal.pone.0064069  0.52
2013 Holloway CM, Scollard DA, Caldwell CB, Ehrlich L, Kahn HJ, Reilly RM. Phase I trial of intraoperative detection of tumor margins in patients with HER2-positive carcinoma of the breast following administration of 111In-DTPA-trastuzumab Fab fragments. Nuclear Medicine and Biology. 40: 630-7. PMID 23618841 DOI: 10.1016/j.nucmedbio.2013.03.005  0.52
2013 Chan C, Cai Z, Reilly RM. Trastuzumab labeled to high specific activity with ¹¹¹In by conjugation to G4 PAMAM dendrimers derivatized with multiple DTPA chelators exhibits increased cytotoxic potency on HER2-positive breast cancer cells. Pharmaceutical Research. 30: 1999-2009. PMID 23615858 DOI: 10.1007/s11095-013-1044-1  0.52
2013 Lechtman E, Mashouf S, Chattopadhyay N, Keller BM, Lai P, Cai Z, Reilly RM, Pignol JP. A Monte Carlo-based model of gold nanoparticle radiosensitization accounting for increased radiobiological effectiveness. Physics in Medicine and Biology. 58: 3075-87. PMID 23594417 DOI: 10.1088/0031-9155/58/10/3075  0.52
2013 Razumienko E, Dryden L, Scollard D, Reilly RM. MicroSPECT/CT imaging of co-expressed HER2 and EGFR on subcutaneous human tumor xenografts in athymic mice using ¹¹¹In-labeled bispecific radioimmunoconjugates. Breast Cancer Research and Treatment. 138: 709-18. PMID 23525982 DOI: 10.1007/s10549-013-2490-5  0.4
2013 Vasdev N, Green DE, Vines DC, McLarty K, McCormick PN, Moran MD, Houle S, Wilson AA, Reilly RM. Positron-emission tomography imaging of the TSPO with [18F]FEPPA in a preclinical breast cancer model Cancer Biotherapy and Radiopharmaceuticals. 28: 254-259. PMID 23350894 DOI: 10.1089/cbr.2012.1196  0.52
2013 Chattopadhyay N, Cai Z, Kwon YL, Lechtman E, Pignol JP, Reilly RM. Molecularly targeted gold nanoparticles enhance the radiation response of breast cancer cells and tumor xenografts to X-radiation. Breast Cancer Research and Treatment. 137: 81-91. PMID 23160926 DOI: 10.1007/s10549-012-2338-4  0.52
2013 Boyle AJ, Liu P, Lu Y, Weinrich D, Scollard DA, Ngo Njock Mbong G, Winnik MA, Reilly RM. The effect of metal-chelating polymers (MCPs) for 111In complexed via the streptavidin-biotin system to trastuzumab Fab fragments on tumor and normal tissue distribution in mice. Pharmaceutical Research. 30: 104-16. PMID 22907419 DOI: 10.1007/s11095-012-0853-y  0.52
2012 Liu P, Boyle AJ, Lu Y, Reilly RM, Winnik MA. Biotinylated polyacrylamide-based metal-chelating polymers and their influence on antigen recognition following conjugation to a trastuzumab Fab fragment. Biomacromolecules. 13: 2831-42. PMID 22871127 DOI: 10.1021/bm300843u  0.52
2012 Fasih A, Fonge H, Cai Z, Leyton JV, Tikhomirov I, Done SJ, Reilly RM. ¹¹¹In-Bn-DTPA-nimotuzumab with/without modification with nuclear translocation sequence (NLS) peptides: an Auger electron-emitting radioimmunotherapeutic agent for EGFR-positive and trastuzumab (Herceptin)-resistant breast cancer. Breast Cancer Research and Treatment. 135: 189-200. PMID 22736376 DOI: 10.1007/s10549-012-2137-y  0.52
2012 Chattopadhyay N, Fonge H, Cai Z, Scollard D, Lechtman E, Done SJ, Pignol JP, Reilly RM. Role of antibody-mediated tumor targeting and route of administration in nanoparticle tumor accumulation in vivo. Molecular Pharmaceutics. 9: 2168-79. PMID 22734589 DOI: 10.1021/mp300016p  0.52
2012 Lu Y, Chau M, Boyle AJ, Liu P, Niehoff A, Weinrich D, Reilly RM, Winnik MA. Effect of pendant group structure on the hydrolytic stability of polyaspartamide polymers under physiological conditions. Biomacromolecules. 13: 1296-306. PMID 22471754 DOI: 10.1021/bm2018239  0.52
2012 Fonge H, Huang H, Scollard D, Reilly RM, Allen C. Influence of formulation variables on the biodistribution of multifunctional block copolymer micelles. Journal of Controlled Release : Official Journal of the Controlled Release Society. 157: 366-74. PMID 21982897 DOI: 10.1016/j.jconrel.2011.09.088  0.4
2011 McLarty K, Moran MD, Scollard DA, Chan C, Sabha N, Mukherjee J, Guha A, McLaurin J, Nitz M, Houle S, Wilson AA, Reilly RM, Vasdev N. Comparisons of [18F]-1-deoxy-1-fluoro-scyllo-inositol with [18F]-FDG for PET imaging of inflammation, breast and brain cancer xenografts in athymic mice. Nuclear Medicine and Biology. 38: 953-9. PMID 21982567 DOI: 10.1016/j.nucmedbio.2011.02.017  0.52
2011 Cai Z, Chattopadhyay N, Liu WJ, Chan C, Pignol JP, Reilly RM. Optimized digital counting colonies of clonogenic assays using ImageJ software and customized macros: comparison with manual counting. International Journal of Radiation Biology. 87: 1135-46. PMID 21913819 DOI: 10.3109/09553002.2011.622033  0.52
2010 Chattopadhyay N, Cai Z, Pignol JP, Keller B, Lechtman E, Bendayan R, Reilly RM. Design and characterization of HER-2-targeted gold nanoparticles for enhanced X-radiation treatment of locally advanced breast cancer. Molecular Pharmaceutics. 7: 2194-206. PMID 20973534 DOI: 10.1021/mp100207t  0.52
2010 Costantini DL, McLarty K, Lee H, Done SJ, Vallis KA, Reilly RM. Antitumor effects and normal-tissue toxicity of 111In-nuclear localization sequence-trastuzumab in athymic mice bearing HER-positive human breast cancer xenografts. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 51: 1084-91. PMID 20554744 DOI: 10.2967/jnumed.109.072389  0.4
2010 Lee H, Fonge H, Hoang B, Reilly RM, Allen C. The effects of particle size and molecular targeting on the intratumoral and subcellular distribution of polymeric nanoparticles. Molecular Pharmaceutics. 7: 1195-208. PMID 20476759 DOI: 10.1021/mp100038h  0.4
2010 Lee H, Hoang B, Fonge H, Reilly RM, Allen C. In vivo distribution of polymeric nanoparticles at the whole-body, tumor, and cellular levels. Pharmaceutical Research. 27: 2343-55. PMID 20195708 DOI: 10.1007/s11095-010-0068-z  0.4
2010 Chan C, Cai Z, Su R, Reilly RM. 111In- or 99mTc-labeled recombinant VEGF bioconjugates: in vitro evaluation of their cytotoxicity on porcine aortic endothelial cells overexpressing Flt-1 receptors. Nuclear Medicine and Biology. 37: 105-15. PMID 20152709 DOI: 10.1016/j.nucmedbio.2009.10.001  0.52
2010 Cai Z, Pignol JP, Chan C, Reilly RM. Cellular dosimetry of (111)In using monte carlo N-particle computer code: comparison with analytic methods and correlation with in vitro cytotoxicity. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 51: 462-70. PMID 20150261 DOI: 10.2967/jnumed.109.063156  0.52
2010 Fonge H, Lee H, Reilly RM, Allen C. Multifunctional block copolymer micelles for the delivery of 111In to EGFR-positive breast cancer cells for targeted Auger electron radiotherapy. Molecular Pharmaceutics. 7: 177-86. PMID 19924993 DOI: 10.1021/mp900201v  0.4
2009 McLarty K, Fasih A, Scollard DA, Done SJ, Vines DC, Green DE, Costantini DL, Reilly RM. 18F-FDG small-animal PET/CT differentiates trastuzumab-responsive from unresponsive human breast cancer xenografts in athymic mice. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 50: 1848-56. PMID 19837760 DOI: 10.2967/jnumed.109.067231  0.52
2009 Vasdev N, Chio J, van Oosten EM, Nitz M, McLaurin J, Vines DC, Houle S, Reilly RM, Wilson AA. Synthesis and preliminary biological evaluations of [18F]-1-deoxy-1-fluoro-scyllo-inositol. Chemical Communications (Cambridge, England). 5527-9. PMID 19753345 DOI: 10.1039/b913317h  0.52
2009 McLarty K, Cornelissen B, Cai Z, Scollard DA, Costantini DL, Done SJ, Reilly RM. Micro-SPECT/CT with 111In-DTPA-pertuzumab sensitively detects trastuzumab-mediated HER2 downregulation and tumor response in athymic mice bearing MDA-MB-361 human breast cancer xenografts. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 50: 1340-8. PMID 19617342 DOI: 10.2967/jnumed.109.062224  0.52
2009 Cai Z, Vallis KA, Reilly RM. Computational analysis of the number, area and density of gamma-H2AX foci in breast cancer cells exposed to (111)In-DTPA-hEGF or gamma-rays using Image-J software. International Journal of Radiation Biology. 85: 262-71. PMID 19296344 DOI: 10.1080/09553000902748757  0.52
2009 McLarty K, Cornelissen B, Scollard DA, Done SJ, Chun K, Reilly RM. Associations between the uptake of 111In-DTPA-trastuzumab, HER2 density and response to trastuzumab (Herceptin) in athymic mice bearing subcutaneous human tumour xenografts. European Journal of Nuclear Medicine and Molecular Imaging. 36: 81-93. PMID 18712381 DOI: 10.1007/s00259-008-0923-x  0.4
2008 Cai Z, Chen Z, Bailey KE, Scollard DA, Reilly RM, Vallis KA. Relationship between induction of phosphorylated H2AX and survival in breast cancer cells exposed to 111In-DTPA-hEGF. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 49: 1353-61. PMID 18632822 DOI: 10.2967/jnumed.108.051805  0.52
2007 Hu M, Scollard D, Chan C, Chen P, Vallis K, Reilly RM. Effect of the EGFR density of breast cancer cells on nuclear importation, in vitro cytotoxicity, and tumor and normal-tissue uptake of [111In]DTPA-hEGF. Nuclear Medicine and Biology. 34: 887-96. PMID 17998090 DOI: 10.1016/j.nucmedbio.2007.06.010  0.4
2007 Bailey KE, Costantini DL, Cai Z, Scollard DA, Chen Z, Reilly RM, Vallis KA. Epidermal growth factor receptor inhibition modulates the nuclear localization and cytotoxicity of the Auger electron emitting radiopharmaceutical 111In-DTPA human epidermal growth factor. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 48: 1562-70. PMID 17704253 DOI: 10.2967/jnumed.107.044073  0.52
2007 Costantini DL, Chan C, Cai Z, Vallis KA, Reilly RM. (111)In-labeled trastuzumab (Herceptin) modified with nuclear localization sequences (NLS): an Auger electron-emitting radiotherapeutic agent for HER2/neu-amplified breast cancer. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 48: 1357-68. PMID 17631548 DOI: 10.2967/jnumed.106.037937  0.52
2007 Tang Y, Yang S, Gariépy J, Scollard DA, Reilly RM. Construction and evaluation of the tumor imaging properties of 123I-labeled recombinant and enzymatically generated Fab fragments of the TAG-72 monoclonal antibody CC49 Bioconjugate Chemistry. 18: 677-684. PMID 17361988 DOI: 10.1021/bc060260r  0.52
2006 Reilly RM, Chen P, Wang J, Scollard D, Cameron R, Vallis KA. Preclinical pharmacokinetic, biodistribution, toxicology, and dosimetry studies of 111In-DTPA-human epidermal growth factor: an auger electron-emitting radiotherapeutic agent for epidermal growth factor receptor-positive breast cancer. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 47: 1023-31. PMID 16741313  0.4
2005 Tang Y, Scollard D, Chen P, Wang J, Holloway C, Reilly RM. Imaging of HER2/neu expression in BT-474 human breast cancer xenografts in athymic mice using [(99m)Tc]-HYNIC-trastuzumab (Herceptin) Fab fragments. Nuclear Medicine Communications. 26: 427-32. PMID 15838425  0.4
2004 McCart JA, Mehta N, Scollard D, Reilly RM, Carrasquillo JA, Tang N, Deng H, Miller M, Xu H, Libutti SK, Alexander HR, Bartlett DL. Oncolytic vaccinia virus expressing the human somatostatin receptor SSTR2: molecular imaging after systemic delivery using 111In-pentetreotide. Molecular Therapy : the Journal of the American Society of Gene Therapy. 10: 553-61. PMID 15336655 DOI: 10.1016/j.ymthe.2004.06.158  0.4
2004 Reilly RM, Scollard DA, Wang J, Mondal H, Chen P, Henderson LA, Bowen BM, Vallis KA. A kit formulated under good manufacturing practices for labeling human epidermal growth factor with 111In for radiotherapeutic applications. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 45: 701-8. PMID 15073268  0.52
2002 Wang J, Reilly RM, Chen P, Yang S, Bray MR, Gariépy J, Chan C, Sandhu J. Fusion of the CH1 domain of IgG1 to epidermal growth factor (EGF) prolongs its retention in the blood but does not increase tumor uptake Cancer Biotherapy and Radiopharmaceuticals. 17: 665-671. PMID 12537670  0.52
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