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Murray Korc - Publications

Affiliations: 
Pharmacology and Toxicology Dartmouth College, Hanover, NH, United States 
Area:
Pharmacology, Biochemistry, General
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Year Citation  Score
2023 Korc M. Heparin Prowess: Favorable Vascular-Immune Reprogramming in Pancreatic Cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 37099035 DOI: 10.1158/1078-0432.CCR-23-0346  0.313
2020 Sasaki N, Gomi F, Yoshimura H, Yamamoto M, Matsuda Y, Michishita M, Hatakeyama H, Kawano Y, Toyoda M, Korc M, Ishiwata T. FGFR4 Inhibitor BLU9931 Attenuates Pancreatic Cancer Cell Proliferation and Invasion While Inducing Senescence: Evidence for Senolytic Therapy Potential in Pancreatic Cancer. Cancers. 12. PMID 33066597 DOI: 10.3390/cancers12102976  0.366
2019 Kornmann M, Lopez M, Beger H, Korc M. Expression of the IIIc Variant of FGF Receptor-1 Confers Mitogenic Responsiveness to Heparin and FGF-5 in TAKA-1 Pancreatic Ductal Cells. International Journal of Gastrointestinal Cancer. 29: 85-92. PMID 12754391  0.323
2019 McElyea S, Korc M. Abstract C31: The glycosaminoglycan syndecan-4 facilitates pancreatic cancer progression and biologic aggressiveness Cancer Research. 79. DOI: 10.1158/1538-7445.Panca19-C31  0.434
2018 Lin CC, Korc M. Designer hydrogels: Shedding light on the physical chemistry of the pancreatic cancer microenvironment. Cancer Letters. PMID 30118843 DOI: 10.1016/j.canlet.2018.08.008  0.321
2018 Korc M. Beyond Kras: MYC Rules in Pancreatic Cancer. Cellular and Molecular Gastroenterology and Hepatology. 6: 223-224. PMID 30105283 DOI: 10.1016/j.jcmgh.2018.04.009  0.345
2018 Danilov AV, Neupane D, Nagaraja AS, Feofanova EV, Humphries LA, DiRenzo J, Korc M. Correction: DeltaNp63alpha-Mediated Induction of Epidermal Growth Factor Receptor Promotes Pancreatic Cancer Cell Growth and Chemoresistance. Plos One. 13: e0192927. PMID 29420628 DOI: 10.1371/journal.pone.0192927  0.793
2017 Ouyang H, Gore J, Deitz S, Korc M. microRNA-10b enhances pancreatic cancer cell invasion by suppressing TIP30 expression and promoting EGF and TGF-β actions. Oncogene. PMID 28604742 DOI: 10.1038/onc.2017.190  0.356
2017 Prabhu L, Wei H, Chen L, Demir Ö, Sandusky G, Sun E, Wang J, Mo J, Zeng L, Fishel M, Safa A, Amaro R, Korc M, Zhang ZY, Lu T. Adapting AlphaLISA high throughput screen to discover a novel small-molecule inhibitor targeting protein arginine methyltransferase 5 in pancreatic and colorectal cancers. Oncotarget. PMID 28591716 DOI: 10.18632/Oncotarget.18102  0.302
2017 Lai X, Wang M, McElyea SD, Sherman S, House M, Korc M. A microRNA signature in circulating exosomes is superior to exosomal glypican-1 levels for diagnosing pancreatic cancer. Cancer Letters. PMID 28232049 DOI: 10.1016/J.Canlet.2017.02.019  0.363
2016 Korc M. RelA: a tale of a stitch in time. The Journal of Clinical Investigation. PMID 27454293 DOI: 10.1172/JCI89156  0.308
2016 Gore J, Imasuen-Williams IE, Conteh AM, Craven KE, Cheng M, Korc M. Combined targeting of TGF-beta, EGFR and HER2 suppresses lymphangiogenesis and metastasis in a pancreatic cancer model. Cancer Letters. PMID 27267807 DOI: 10.1016/j.canlet.2016.05.037  0.362
2016 Muratore S, Zeng X, Korc M, McElyea S, Wilhelm J, Bellin M, Beilman G. Metastatic Pancreatic Adenocarcinoma After Total Pancreatectomy Islet Autotransplantation for Chronic Pancreatitis. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 27137483 DOI: 10.1111/Ajt.13851  0.394
2015 Craven KE, Gore J, Wilson JL, Korc M. Angiogenic gene signature in human pancreatic cancer correlates with TGF-beta and inflammatory transcriptomes. Oncotarget. PMID 26586478 DOI: 10.18632/oncotarget.6345  0.346
2015 Palam LR, Gore J, Craven KE, Wilson JL, Korc M. Integrated stress response is critical for gemcitabine resistance in pancreatic ductal adenocarcinoma. Cell Death & Disease. 6: e1913. PMID 26469962 DOI: 10.1038/Cddis.2015.264  0.312
2015 Joshi GK, Deitz-McElyea S, Liyanage T, Lawrence K, Mali S, Sardar R, Korc M. Label-Free Nanoplasmonic-Based Short Noncoding RNA Sensing at Attomolar Concentrations Allows for Quantitative and Highly Specific Assay of MicroRNA-10b in Biological Fluids and Circulating Exosomes. Acs Nano. 9: 11075-89. PMID 26444644 DOI: 10.1021/Acsnano.5B04527  0.302
2015 Kwon JJ, Nabinger SC, Vega Z, Sahu SS, Alluri RK, Abdul-Sater Z, Yu Z, Gore J, Nalepa G, Saxena R, Korc M, Kota J. Pathophysiological role of microRNA-29 in pancreatic cancer stroma. Scientific Reports. 5: 11450. PMID 26095125 DOI: 10.1038/srep11450  0.329
2015 Gore J, Craven KE, Wilson JL, Cote GA, Cheng M, Nguyen HV, Cramer HM, Sherman S, Korc M. TCGA data and patient-derived orthotopic xenografts highlight pancreatic cancer-associated angiogenesis. Oncotarget. 6: 7504-21. PMID 25762644  0.322
2015 Korc M. Pancreatic cancer-associated diabetes is an "exosomopathy". Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 1508-10. PMID 25645860 DOI: 10.1158/1078-0432.CCR-14-2990  0.315
2014 Ki CS, Lin TY, Korc M, Lin CC. Thiol-ene hydrogels as desmoplasia-mimetic matrices for modeling pancreatic cancer cell growth, invasion, and drug resistance. Biomaterials. 35: 9668-77. PMID 25176061 DOI: 10.1016/j.biomaterials.2014.08.014  0.348
2014 Gore J, Korc M. Pancreatic cancer stroma: friend or foe? Cancer Cell. 25: 711-2. PMID 24937454 DOI: 10.1016/j.ccr.2014.05.026  0.357
2014 Matsuda Y, Yoshimura H, Ueda J, Naito Z, Korc M, Ishiwata T. Nestin delineates pancreatic cancer stem cells in metastatic foci of NOD/Shi-scid IL2Rγ(null) (NOG) mice. The American Journal of Pathology. 184: 674-85. PMID 24412093 DOI: 10.1016/j.ajpath.2013.11.014  0.317
2014 Liu F, Gore AJ, Wilson JL, Korc M. DUSP1 is a novel target for enhancing pancreatic cancer cell sensitivity to gemcitabine. Plos One. 9: e84982. PMID 24409315 DOI: 10.1371/journal.pone.0084982  0.309
2014 Ouyang H, Gore J, Deitz S, Korc M. microRNA-10b enhances pancreatic cancer cell invasion by suppressing TIP30 expression and promoting EGF and TGF-β actions. Oncogene. 33: 4664-74. PMID 24096486 DOI: 10.1038/onc.2013.405  0.775
2014 Ueda J, Matsuda Y, Yamahatsu K, Uchida E, Naito Z, Korc M, Ishiwata T. Epithelial splicing regulatory protein 1 is a favorable prognostic factor in pancreatic cancer that attenuates pancreatic metastases. Oncogene. 33: 4485-95. PMID 24077287 DOI: 10.1038/onc.2013.392  0.427
2013 Sempere LF, Korc M. A method for conducting highly sensitive microRNA in situ hybridization and immunohistochemical analysis in pancreatic cancer. Methods in Molecular Biology (Clifton, N.J.). 980: 43-59. PMID 23359149 DOI: 10.1007/978-1-62703-287-2_4  0.42
2013 Norris AM, Gore A, Balboni A, Young A, Longnecker DS, Korc M. AGR2 is a SMAD4-suppressible gene that modulates MUC1 levels and promotes the initiation and progression of pancreatic intraepithelial neoplasia. Oncogene. 32: 3867-76. PMID 22945649 DOI: 10.1038/Onc.2012.394  0.407
2012 Thornley JA, Trask HW, Ringelberg CS, Ridley CJ, Wang S, Sal-Lari RC, Moore JH, Korc M, Tomlinson CR. SMAD4-dependent polysome RNA recruitment in human pancreatic cancer cells. Molecular Carcinogenesis. 51: 771-82. PMID 22965423 DOI: 10.1002/Mc.20845  0.415
2012 Deharvengt S, Marmarelis M, Korc M. Concomitant targeting of EGF receptor, TGF-beta and SRC points to a novel therapeutic approach in pancreatic cancer. Plos One. 7: e39684. PMID 22761868 DOI: 10.1371/journal.pone.0039684  0.329
2012 Ishiwata T, Matsuda Y, Yamamoto T, Uchida E, Korc M, Naito Z. Enhanced expression of fibroblast growth factor receptor 2 IIIc promotes human pancreatic cancer cell proliferation. The American Journal of Pathology. 180: 1928-41. PMID 22440254 DOI: 10.1016/j.ajpath.2012.01.020  0.446
2012 Whipple CA, Young AL, Korc M. A KrasG12D-driven genetic mouse model of pancreatic cancer requires glypican-1 for efficient proliferation and angiogenesis Oncogene. 31: 2535-2544. PMID 21996748 DOI: 10.1038/Onc.2011.430  0.409
2012 Ebert M, Yokoyama M, Kobrin M, Friess H, Buchler M, Korc M. Increased mdm2 expression and immunoreactivity in human pancreatic ductal adenocarcinoma. International Journal of Oncology. 5: 1279-84. PMID 21559710 DOI: 10.3892/Ijo.5.6.1279  0.465
2012 Yokoyama M, Ebert M, Funatomi H, Friess H, Buchler M, Johnson G, Korc M. Amphiregulin is a potent mitogen in human pancreatic-cancer cells - correlation with patient survival. International Journal of Oncology. 6: 625-31. PMID 21556580 DOI: 10.3892/ijo.6.3.625  0.407
2012 Yokoyama M, Funatomi H, Kobrin M, Ebert M, Friess H, Buchler M, Korc M. Betacellulin, a member of the epidermal growth-factor family, is overexpressed in human pancreatic-cancer. International Journal of Oncology. 7: 825-9. PMID 21552910 DOI: 10.3892/ijo.7.4.825  0.451
2012 Yokoyama M, Funatomi H, Hope C, Damm D, Friess H, Buchler M, Abraham J, Korc M. Heparin-binding EGF-like growth factor expression and biological action in human pancreatic cancer cells. International Journal of Oncology. 8: 289-95. PMID 21544358 DOI: 10.3892/ijo.8.2.289  0.417
2011 Carrière C, Young AL, Gunn JR, Longnecker DS, Korc M. Acute pancreatitis accelerates initiation and progression to pancreatic cancer in mice expressing oncogenic Kras in the Nestin cell lineage Plos One. 6. PMID 22140463 DOI: 10.1371/Journal.Pone.0027725  0.42
2011 Preis M, Korc M. Signaling pathways in pancreatic cancer. Critical Reviews in Eukaryotic Gene Expression. 21: 115-29. PMID 22077151  0.368
2011 Danilov AV, Neupane D, Nagaraja AS, Feofanova EV, Humphries LA, DiRenzo J, Korc M. DeltaNp63alpha-mediated induction of epidermal growth factor receptor promotes pancreatic cancer cell growth and chemoresistance. Plos One. 6: e26815. PMID 22053213 DOI: 10.1371/Journal.Pone.0026815  0.819
2011 Carrire C, Gore AJ, Norris AM, Gunn JR, Young AL, Longnecker DS, Korc M. Deletion of Rb accelerates pancreatic carcinogenesis by oncogenic kras and impairs senescence in premalignant lesions Gastroenterology. 141: 1091-1101. PMID 21699781 DOI: 10.1053/J.Gastro.2011.05.041  0.479
2011 Wang Z, Banerjee S, Ahmad A, Li Y, Azmi AS, Gunn JR, Kong D, Bao B, Ali S, Gao J, Mohammad RM, Miele L, Korc M, Sarkar FH. Activated K-ras and INK4a/Arf deficiency cooperate during the development of pancreatic cancer by activation of Notch and NF-κB signaling pathways. Plos One. 6: e20537. PMID 21673986 DOI: 10.1371/Journal.Pone.0020537  0.301
2011 Sempere LF, Gunn JR, Korc M. A novel 3-dimensional culture system uncovers growth stimulatory actions by TGFβ in pancreatic cancer cells. Cancer Biology & Therapy. 12: 198-207. PMID 21613822 DOI: 10.4161/Cbt.12.3.15979  0.418
2011 Liu X, Sempere LF, Guo Y, Korc M, Kauppinen S, Freemantle SJ, Dmitrovsky E. Involvement of microRNAs in lung cancer biology and therapy. Translational Research : the Journal of Laboratory and Clinical Medicine. 157: 200-8. PMID 21420030 DOI: 10.1016/J.Trsl.2011.01.001  0.377
2011 Matsuda Y, Naito Z, Kawahara K, Nakazawa N, Korc M, Ishiwata T. Nestin is a novel target for suppressing pancreatic cancer cell migration, invasion and metastasis. Cancer Biology & Therapy. 11: 512-23. PMID 21258211 DOI: 10.4161/Cbt.11.5.14673  0.466
2011 Ueda J, Kawahara K, Fujii T, Yamahatsu K, Suzuki T, Matsuda Y, Uchida E, Korc M, Naito Z, Ishiwata T. Abstract 5240: Establishment of novel human pancreatic cancer cell lines from liver and lung metastases in NOD/SCID/γcnull(NOG) mice Cancer Research. 71: 5240-5240. DOI: 10.1158/1538-7445.Am2011-5240  0.45
2011 Whipple CA, Korc M. Abstract 2811: GPC1 promotes tumor growth and angiogenesis in a KrasG12D- Driven mouse model of pancreatic cancer Cancer Research. 71: 2811-2811. DOI: 10.1158/1538-7445.Am2011-2811  0.505
2011 Matsuda Y, Yamahatsu K, Kawahara K, Suzuki T, Fujii T, Yamamoto T, Korc M, Naito Z, Ishiwata T. Abstract 2457: Nestin regulates pancreatic cancer stem cell functions Cancer Research. 71: 2457-2457. DOI: 10.1158/1538-7445.Am2011-2457  0.46
2011 Wang Z, Banerjee S, Ahmad A, Azmi AS, Bao B, Ali S, Mohammad RM, Miele L, Korc M, Sarkar FH. Abstract 2385: Activated Kras and INK4a/Arf deficiency cooperate to produce pancreatic cancer involved with Notch and NF-κB pathways Cancer Research. 71: 2385-2385. DOI: 10.1158/1538-7445.Am2011-2385  0.431
2011 Danilov A, Neupane D, DiRenzo J, Korc M. Abstract 223: ΔNp63α, a p53 family member protein, promotes tumor progression in pancreatic cancer Cancer Research. 71: 223-223. DOI: 10.1158/1538-7445.Am2011-223  0.799
2011 Ishiwata T, Matsuda Y, Kawahara K, Yamamoto T, Teduka K, Suzuki T, Peng W, Korc M, Naito Z. Abstract 1204: Fibroblast growth factor receptor 2 as a novel therapeutic target for cancer cell growth and angiogenesis in human pancreatic cancer Cancer Research. 71: 1204-1204. DOI: 10.1158/1538-7445.Am2011-1204  0.544
2010 Korc M. Driver mutations: a roadmap for getting close and personal in pancreatic cancer. Cancer Biology & Therapy. 10: 588-91. PMID 20716952 DOI: 10.4161/Cbt.10.6.13128  0.371
2010 Sempere LF, Preis M, Yezefski T, Ouyang H, Suriawinata AA, Silahtaroglu A, Conejo-Garcia JR, Kauppinen S, Wells W, Korc M. Fluorescence-based codetection with protein markers reveals distinct cellular compartments for altered MicroRNA expression in solid tumors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 4246-55. PMID 20682703 DOI: 10.1158/1078-0432.Ccr-10-1152  0.761
2010 Liu X, Sempere LF, Ouyang H, Memoli VA, Andrew AS, Luo Y, Demidenko E, Korc M, Shi W, Preis M, Dragnev KH, Li H, Direnzo J, Bak M, Freemantle SJ, et al. MicroRNA-31 functions as an oncogenic microRNA in mouse and human lung cancer cells by repressing specific tumor suppressors. The Journal of Clinical Investigation. 120: 1298-309. PMID 20237410 DOI: 10.1172/Jci39566  0.778
2010 Deharvengt SJ, Gunn JR, Pickett SB, Korc M. Intratumoral delivery of shRNA targeting cyclin D1 attenuates pancreatic cancer growth. Cancer Gene Therapy. 17: 325-33. PMID 19851352 DOI: 10.1038/Cgt.2009.75  0.458
2010 Sempere LF, Preis M, Yezefski T, Ouyang H, Suriawinata AA, Silahtaroglu A, Conejo-Garcia JR, Kauppinen S, Wells W, Korc M. Abstract LB-360: Fluorescence-based co-registration with protein markers reveals distinct cellular compartments for altered microRNA expression in solid tumors Cancer Research. 70. DOI: 10.1158/1538-7445.Am10-Lb-360  0.407
2010 Liu X, Sempere LF, Ouyang H, Memoli VA, Andrew AS, Luo Y, Demidenko E, Korc M, Shi W, Preis M, Dragnev KH, Liu H, DiRenzo J, Bak M, Kauppinen S, et al. Abstract 5698: MicroRNA-31 acts as an oncomir in lung cancer by repressing specific tumor suppressors Cancer Research. 70: 5698-5698. DOI: 10.1158/1538-7445.Am10-5698  0.777
2010 Ishiwata T, Matsuda Y, Kawahara K, Yamamoto T, Teduka K, Uchida E, Korc M, Naito Z. Abstract 4101: Fibroblast growth factor receptor (FGFR) 2 IIIc, is a novel molecular target for suppressing pancreatic cancer cell growth and migration Cancer Research. 70: 4101-4101. DOI: 10.1158/1538-7445.Am10-4101  0.543
2010 Matsuda Y, Ishiwata T, Kawamoto M, Yamomoto T, Kawahara K, Teduka K, Peng W, Yamahatsu K, Korc M, Naito Z. Abstract 408: Stem cell marker Nestin regulated the migration and invasion of pancreatic cancer cells Cancer Research. 70: 408-408. DOI: 10.1158/1538-7445.Am10-408  0.487
2009 Korc M. Smad4: gatekeeper gene in head and neck squamous cell carcinoma. The Journal of Clinical Investigation. 119: 3208-11. PMID 19841540 DOI: 10.1172/Jci41230  0.39
2009 Korc M, Friesel RE. The role of fibroblast growth factors in tumor growth. Current Cancer Drug Targets. 9: 639-51. PMID 19508171 DOI: 10.2174/156800909789057006  0.379
2009 Shin S, Asano T, Yao Y, Zhang R, Claret FX, Korc M, Sabapathy K, Menter DG, Abbruzzese JL, Reddy SA. Activator protein-1 has an essential role in pancreatic cancer cells and is regulated by a novel Akt-mediated mechanism. Molecular Cancer Research : McR. 7: 745-54. PMID 19435822 DOI: 10.1158/1541-7786.Mcr-08-0462  0.435
2009 Carrière C, Young AL, Gunn JR, Longnecker DS, Korc M. Acute pancreatitis markedly accelerates pancreatic cancer progression in mice expressing oncogenic Kras. Biochemical and Biophysical Research Communications. 382: 561-5. PMID 19292977 DOI: 10.1016/J.Bbrc.2009.03.068  0.457
2009 Liu X, Sempere LF, Galimberti F, Freemantle SJ, Black C, Dragnev KH, Yan M, Fiering S, Memoli V, Li H, Direnzo J, Korc M, Cole CN, Bak M, Kauppinen S, et al. Uncovering growth-Suppressive micro rNAs in lung cancer Clinical Cancer Research. 15: 1177-1183. PMID 19228723 DOI: 10.1158/1078-0432.Ccr-08-1355  0.403
2009 Seeley ES, Carrière C, Goetze T, Longnecker DS, Korc M. Pancreatic cancer and precursor pancreatic intraepithelial neoplasia lesions are devoid of primary cilia. Cancer Research. 69: 422-30. PMID 19147554 DOI: 10.1158/0008-5472.CAN-08-1290  0.383
2009 Ketterer K, Kong B, Frank D, Giese NA, Bauer A, Hoheisel J, Korc M, Kleeff J, Michalski CW, Friess H. Neuromedin U is overexpressed in pancreatic cancer and increases invasiveness via the hepatocyte growth factor c-Met pathway. Cancer Letters. 277: 72-81. PMID 19118941 DOI: 10.1016/J.Canlet.2008.11.028  0.518
2009 Bauer A, Kleeff J, Bier M, Wirtz M, Kayed H, Esposito I, Korc M, Hafner M, Hoheisel JD, Friess H. Identification of malignancy factors by analyzing cystic tumors of the pancreas. Pancreatology : Official Journal of the International Association of Pancreatology (Iap) ... [Et Al.]. 9: 34-44. PMID 19077453 DOI: 10.1159/000178873  0.347
2009 Kawamoto M, Ishiwata T, Cho K, Uchida E, Korc M, Naito Z, Tajiri T. Nestin expression correlates with nerve and retroperitoneal tissue invasion in pancreatic cancer. Human Pathology. 40: 189-98. PMID 18799194 DOI: 10.1016/J.Humpath.2008.02.022  0.494
2009 Formentini A, Prokopchuk O, Sträter J, Kleeff J, Grochola LF, Leder G, Henne-Bruns D, Korc M, Kornmann M. Interleukin-13 exerts autocrine growth-promoting effects on human pancreatic cancer, and its expression correlates with a propensity for lymph node metastases. International Journal of Colorectal Disease. 24: 57-67. PMID 18758789 DOI: 10.1007/S00384-008-0550-9  0.39
2008 Whipple CA, Lander AD, Korc M. Discovery of a novel molecule that regulates tumor growth and metastasis. Thescientificworldjournal. 8: 1250-3. PMID 19082421 DOI: 10.1100/Tsw.2008.152  0.477
2008 Neupane D, Korc M. 14-3-3sigma Modulates pancreatic cancer cell survival and invasiveness. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 7614-23. PMID 19047086 DOI: 10.1158/1078-0432.CCR-08-1366  0.798
2008 Szafranska AE, Doleshal M, Edmunds HS, Gordon S, Luttges J, Munding JB, Barth RJ, Gutmann EJ, Suriawinata AA, Marc Pipas J, Tannapfel A, Korc M, Hahn SA, Labourier E, Tsongalis GJ. Analysis of microRNAs in pancreatic fine-needle aspirates can classify benign and malignant tissues. Clinical Chemistry. 54: 1716-24. PMID 18719196 DOI: 10.1373/Clinchem.2008.109603  0.374
2008 Sempere LF, Korc M. Shining the spotlight on shed KRAS in pancreatic cancer. Cancer Biology & Therapy. 7: 361-3. PMID 18614859 DOI: 10.4161/Cbt.7.3.5582  0.492
2008 Whipple C, Korc M. Targeting angiogenesis in pancreatic cancer: Rationale and pitfalls Langenbeck's Archives of Surgery. 393: 901-910. PMID 18210149 DOI: 10.1007/S00423-008-0280-Z  0.445
2008 Aikawa T, Whipple CA, Lopez ME, Gunn J, Young A, Lander AD, Korc M. Glypican-1 modulates the angiogenic and metastatic potential of human and mouse cancer cells. The Journal of Clinical Investigation. 118: 89-99. PMID 18064304 DOI: 10.1172/Jci32412  0.406
2008 Liu X, Sempere L, Galimberti F, Freemantle S, Black C, Fiering S, Cole C, Dragnev K, Memoli V, Korc M, Li H, DiRenzo J, Bak M, Kauppinen S, Dmitrovsky E. Abstract A135: Uncovering tumor suppressive and oncogenic microRNAs in lung cancer Cancer Prevention Research. 1. DOI: 10.1158/1940-6207.Prev-08-A135  0.402
2008 Ishiwata T, Kawamoto M, Kawamoto Y, Teduka K, Matsuda Y, Onda M, Uchida E, Tajiri T, Korc M, Naito Z. OVER-EXPRESSION OF FGFR2 IIIC ISOFORM ENHANCES THE GROWTH OF PANCREATIC CANCER Pancreas. 37: 476. DOI: 10.1097/01.mpa.0000335480.46603.d9  0.41
2007 Chang KC, Komm B, Arnold NB, Korc M. The application of differential display as a gene profiling tool. Methods in Molecular Biology (Clifton, N.J.). 383: 31-40. PMID 18217677 DOI: 10.1007/978-1-59745-335-6_3  0.317
2007 Korc M. Pancreatic cancer-associated stroma production. American Journal of Surgery. 194: S84-6. PMID 17903452 DOI: 10.1016/J.Amjsurg.2007.05.004  0.484
2007 Cho K, Ishiwata T, Uchida E, Nakazawa N, Korc M, Naito Z, Tajiri T. Enhanced expression of keratinocyte growth factor and its receptor correlates with venous invasion in pancreatic cancer. The American Journal of Pathology. 170: 1964-74. PMID 17525264 DOI: 10.2353/Ajpath.2007.060935  0.508
2007 Liu Z, Neiss N, Zhou S, Henne-Bruns D, Korc M, Bachem M, Kornmann M. Identification of a fibroblast growth factor receptor 1 splice variant that inhibits pancreatic cancer cell growth. Cancer Research. 67: 2712-9. PMID 17363592 DOI: 10.1158/0008-5472.CAN-06-3843  0.439
2007 Arnold NB, Arkus N, Gunn J, Korc M. The histone deacetylase inhibitor suberoylanilide hydroxamic acid induces growth inhibition and enhances gemcitabine-induced cell death in pancreatic cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 18-26. PMID 17200334 DOI: 10.1158/1078-0432.Ccr-06-0914  0.476
2007 Kolb A, Kleeff J, Arnold N, Giese NA, Giese T, Korc M, Friess H. Expression and differential signaling of heregulins in pancreatic cancer cells. International Journal of Cancer. 120: 514-23. PMID 17096356 DOI: 10.1002/Ijc.22360  0.554
2007 Matsushita A, Götze T, Kawamoto M, Cho K, Nakamura Y, Aimoto T, Uchida E, Ishiwata T, Naito Z, Tajiri T, Korc M. NEUROPILIN-1 ASSOCIATION WITH c-MET IN PANCREATIC CANCER CELLS ENHANCES HEPATOCYTE GROWTH FACTOR-MEDIATED CELL INVASION Pancreas. 35: 415. DOI: 10.1097/01.mpa.0000297744.81562.ac  0.398
2006 Tomlinson CR, Korc M. Squeezing data from pancreatic juice. Cancer Biology & Therapy. 5: 1390-1. PMID 17172808 DOI: 10.4161/Cbt.5.10.3486  0.342
2006 Kayed H, Kleeff J, Keleg S, Jiang X, Penzel R, Giese T, Zentgraf H, Büchler MW, Korc M, Friess H. Correlation of glypican-1 expression with TGF-beta, BMP, and activin receptors in pancreatic ductal adenocarcinoma. International Journal of Oncology. 29: 1139-48. PMID 17016645  0.347
2006 Aikawa T, Gunn J, Spong SM, Klaus SJ, Korc M. Connective tissue growth factor-specific antibody attenuates tumor growth, metastasis, and angiogenesis in an orthotopic mouse model of pancreatic cancer. Molecular Cancer Therapeutics. 5: 1108-16. PMID 16731742 DOI: 10.1158/1535-7163.MCT-05-0516  0.429
2006 Guo J, Kleeff J, Zhao Y, Li J, Giese T, Esposito I, Büchler MW, Korc M, Friess H. Yes-associated protein (YAP65) in relation to Smad7 expression in human pancreatic ductal adenocarcinoma. International Journal of Molecular Medicine. 17: 761-7. PMID 16596258 DOI: 10.3892/Ijmm.17.5.761  0.487
2006 Ebert MP, Korc M, Malfertheiner P, Röcken C. Advances, challenges, and limitations in serum-proteome-based cancer diagnosis. Journal of Proteome Research. 5: 19-25. PMID 16396491 DOI: 10.1021/Pr050271E  0.375
2006 Kayed H, Kleeff J, Kolb A, Ketterer K, Keleg S, Felix K, Giese T, Penzel R, Zentgraf H, Büchler MW, Korc M, Friess H. FXYD3 is overexpressed in pancreatic ductal adenocarcinoma and influences pancreatic cancer cell growth. International Journal of Cancer. 118: 43-54. PMID 16003754 DOI: 10.1002/Ijc.21257  0.531
2006 Neupane D, Korc M. OVEREXPRESSION OF 14-3-3?? CONFERS A GROWTH AND SURVIVAL ADVANTAGE IN PANCREATIC CANCER Pancreas. 33: 486. DOI: 10.1097/00006676-200611000-00168  0.799
2006 Kornmann M, Zhou S, Henne-Bruns D, Korc M, Bachem M, Liu Z. EXPRESSION OF FGFR1-IIIB INHIBITS PANCREATIC CANCER CELL GROWTH IN VITRO AND IN VIVO Pancreas. 33: 475. DOI: 10.1097/00006676-200611000-00130  0.434
2005 Yasutome M, Gunn J, Korc M. Restoration of Smad4 in BxPC3 pancreatic cancer cells attenuates proliferation without altering angiogenesis. Clinical & Experimental Metastasis. 22: 461-73. PMID 16320109 DOI: 10.1007/S10585-005-2891-X  0.428
2005 Ding K, Lopez-Burks M, Sánchez-Duran JA, Korc M, Lander AD. Growth factor-induced shedding of syndecan-1 confers glypican-1 dependence on mitogenic responses of cancer cells. The Journal of Cell Biology. 171: 729-38. PMID 16286510 DOI: 10.1083/Jcb.200508010  0.429
2005 Chan JK, Pham H, You XJ, Cloven NG, Burger RA, Rose GS, Van Nostrand K, Korc M, Disaia PJ, Fan H. Suppression of ovarian cancer cell tumorigenicity and evasion of Cisplatin resistance using a truncated epidermal growth factor receptor in a rat model. Cancer Research. 65: 3243-8. PMID 15833856 DOI: 10.1158/0008-5472.Can-03-3013  0.435
2005 Boyer Arnold N, Korc M. Smad7 abrogates transforming growth factor-beta1-mediated growth inhibition in COLO-357 cells through functional inactivation of the retinoblastoma protein. The Journal of Biological Chemistry. 280: 21858-66. PMID 15811853 DOI: 10.1074/Jbc.M500583200  0.368
2004 Bloushtain N, Qimron U, Bar-Ilan A, Hershkovitz O, Gazit R, Fima E, Korc M, Vlodavsky I, Bovin NV, Porgador A. Membrane-associated heparan sulfate proteoglycans are involved in the recognition of cellular targets by NKp30 and NKp46. Journal of Immunology (Baltimore, Md. : 1950). 173: 2392-401. PMID 15294952 DOI: 10.4049/Jimmunol.173.4.2392  0.364
2004 Li J, Kleeff J, Kayed H, Felix K, Penzel R, Büchler MW, Korc M, Friess H. Glypican-1 antisense transfection modulates TGF-beta-dependent signaling in Colo-357 pancreatic cancer cells. Biochemical and Biophysical Research Communications. 320: 1148-55. PMID 15249209 DOI: 10.1016/J.Bbrc.2004.06.063  0.484
2004 Li J, Kleeff J, Giese N, Büchler MW, Korc M, Friess H. Gefitinib ('Iressa', ZD1839), a selective epidermal growth factor receptor tyrosine kinase inhibitor, inhibits pancreatic cancer cell growth, invasion, and colony formation. International Journal of Oncology. 25: 203-10. PMID 15202007  0.415
2004 Fukasawa M, Korc M. Vascular endothelial growth factor-trap suppresses tumorigenicity of multiple pancreatic cancer cell lines. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 3327-32. PMID 15161686 DOI: 10.1158/1078-0432.Ccr-03-0820  0.405
2004 Arnold NB, Ketterer K, Kleeff J, Friess H, Büchler MW, Korc M. Thioredoxin is downstream of Smad7 in a pathway that promotes growth and suppresses cisplatin-induced apoptosis in pancreatic cancer. Cancer Research. 64: 3599-606. PMID 15150118 DOI: 10.1158/0008-5472.Can-03-2999  0.497
2004 Guweidhi A, Kleeff J, Giese N, El Fitori J, Ketterer K, Giese T, Büchler MW, Korc M, Friess H. Enhanced expression of 14-3-3sigma in pancreatic cancer and its role in cell cycle regulation and apoptosis. Carcinogenesis. 25: 1575-85. PMID 15073049 DOI: 10.1093/carcin/bgh159  0.398
2004 Fukahi K, Fukasawa M, Neufeld G, Itakura J, Korc M. Aberrant expression of neuropilin-1 and -2 in human pancreatic cancer cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 581-90. PMID 14760080  0.315
2004 Guo J, Kleeff J, Li J, Ding J, Hammer J, Zhao Y, Giese T, Korc M, Büchler MW, Friess H. Expression and functional significance of CDC25B in human pancreatic ductal adenocarcinoma. Oncogene. 23: 71-81. PMID 14712212 DOI: 10.1038/Sj.Onc.1206926  0.507
2004 Kleeff J, Kothari NH, Friess H, Fan H, Korc M. Adenovirus-mediated transfer of a truncated fibroblast growth factor (FGF) type I receptor blocks FGF-2 signaling in multiple pancreatic cancer cell lines. Pancreas. 28: 25-30. PMID 14707726 DOI: 10.1097/00006676-200401000-00004  0.364
2003 Ketterer K, Rao S, Friess H, Weiss J, Büchler MW, Korc M. Reverse transcription-PCR analysis of laser-captured cells points to potential paracrine and autocrine actions of neurotrophins in pancreatic cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 5127-36. PMID 14613990  0.418
2003 Friess H, Ding J, Kleeff J, Fenkell L, Rosinski JA, Guweidhi A, Reidhaar-Olson JF, Korc M, Hammer J, Büchler MW. Microarray-based identification of differentially expressed growth- and metastasis-associated genes in pancreatic cancer Cellular and Molecular Life Sciences. 60: 1180-1199. PMID 12861384 DOI: 10.1007/S00018-003-3036-5  0.418
2003 Liao Q, Guo J, Kleeff J, Zimmermann A, Büchler MW, Korc M, Friess H. Down-regulation of the dual-specificity phosphatase MKP-1 suppresses tumorigenicity of pancreatic cancer cells. Gastroenterology. 124: 1830-45. PMID 12806617 DOI: 10.1016/S0016-5085(03)00398-6  0.441
2003 Friess H, Zhu Z, Liard V, Shi X, Shrikhande SV, Wang L, Lieb K, Korc M, Palma C, Zimmermann A, Reubi JC, Büchler MW. Neurokinin-1 receptor expression and its potential effects on tumor growth in human pancreatic cancer. Laboratory Investigation; a Journal of Technical Methods and Pathology. 83: 731-42. PMID 12746482 DOI: 10.1097/01.Lab.0000067499.57309.F6  0.477
2003 Korc M. Pathways for aberrant angiogenesis in pancreatic cancer. Molecular Cancer. 2: 8. PMID 12556241 DOI: 10.1186/1476-4598-2-8  0.404
2003 Rowland-Goldsmith MA, Maruyama H, Matsuda K, Idezawa T, Ralli M, Ralli S, Korc M. Soluble type II transforming growth factor-beta receptor attenuates expression of metastasis-associated genes and suppresses pancreatic cancer cell metastasis. Molecular Cancer Therapeutics. 1: 161-7. PMID 12467210  0.315
2003 Kleeff J, Friess H, Buechler M, Kothari N, Datta S, Fan H, Korc M. Adenovirus mediated transfer of a truncated fibroblast growth factor (FGF) typ I receptor blocks FGF2 signaling in pancreatic cancer cells Gastroenterology. 124: A104. DOI: 10.1016/S0016-5085(03)80511-5  0.356
2002 Zhu Z, Kleeff J, Kayed H, Wang L, Korc M, Büchler MW, Friess H. Nerve growth factor and enhancement of proliferation, invasion, and tumorigenicity of pancreatic cancer cells. Molecular Carcinogenesis. 35: 138-47. PMID 12410565 DOI: 10.1002/Mc.10083  0.533
2002 Schneider D, Kleeff J, Berberat PO, Zhu Z, Korc M, Friess H, Büchler MW. Induction and expression of betaig-h3 in pancreatic cancer cells. Biochimica Et Biophysica Acta. 1588: 1-6. PMID 12379307 DOI: 10.1016/S0925-4439(02)00052-2  0.438
2002 Matsuda K, Idezawa T, You XJ, Kothari NH, Fan H, Korc M. Multiple mitogenic pathways in pancreatic cancer cells are blocked by a truncated epidermal growth factor receptor. Cancer Research. 62: 5611-7. PMID 12359775  0.399
2002 Zhu Z, Friess H, Kleeff J, Wang L, Wirtz M, Zimmermann A, Korc M, Büchler MW. Glypican-3 expression is markedly decreased in human gastric cancer but not in esophageal cancer. American Journal of Surgery. 184: 78-83. PMID 12135726 DOI: 10.1016/S0002-9610(02)00884-X  0.41
2002 Kornmann M, Ishiwata T, Matsuda K, Lopez ME, Fukahi K, Asano G, Beger HG, Korc M. IIIc isoform of fibroblast growth factor receptor 1 is overexpressed in human pancreatic cancer and enhances tumorigenicity of hamster ductal cells. Gastroenterology. 123: 301-13. PMID 12105858 DOI: 10.1053/Gast.2002.34174  0.472
2002 Kleeff J, Fukahi K, Lopez ME, Friess H, Büchler MW, Sosnowski BA, Korc M. Targeting of suicide gene delivery in pancreatic cancer cells via FGF receptors. Cancer Gene Therapy. 9: 522-32. PMID 12032663 DOI: 10.1038/Sj.Cgt.7700464  0.49
2002 Kornmann M, Lopez ME, Beger HG, Korc M. Expression of the IIIc variant of FGF receptor-1 confers mitogenic responsiveness to heparin and FGF-5 in TAKA-1 pancreatic ductal cells. International Journal of Pancreatology : Official Journal of the International Association of Pancreatology. 29: 85-92. PMID 11876253 DOI: 10.1385/Ijgc:29:2:085  0.401
2002 Tempia-Caliera AA, Horvath LZ, Zimmermann A, Tihanyi TT, Korc M, Friess H, Büchler MW. Adhesion molecules in human pancreatic cancer. Journal of Surgical Oncology. 79: 93-100. PMID 11815996 DOI: 10.1002/Jso.10053  0.335
2001 Xu Z, Friess H, Solioz M, Aebi S, Korc M, Kleeff J, Büchler MW. Bcl-x(L) antisense oligonucleotides induce apoptosis and increase sensitivity of pancreatic cancer cells to gemcitabine. International Journal of Cancer. 94: 268-74. PMID 11668508 DOI: 10.1002/Ijc.1447  0.416
2001 Wildi S, Kleeff J, Maruyama H, Maurer CA, Büchler MW, Korc M. Overexpression of activin A in stage IV colorectal cancer. Gut. 49: 409-17. PMID 11511564 DOI: 10.1136/Gut.49.3.409  0.432
2001 Friess H, Guo XZ, Tempia-Caliera AA, Fukuda A, Martignoni ME, Zimmermann A, Korc M, Büchler MW. Differential expression of metastasis-associated genes in papilla of vater and pancreatic cancer correlates with disease stage. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 19: 2422-32. PMID 11331321 DOI: 10.1200/Jco.2001.19.9.2422  0.469
2001 Tang RF, Itakura J, Aikawa T, Matsuda K, Fujii H, Korc M, Matsumoto Y. Overexpression of lymphangiogenic growth factor VEGF-C in human pancreatic cancer. Pancreas. 22: 285-92. PMID 11291931 DOI: 10.1097/00006676-200104000-00010  0.339
2001 Luo J, Guo P, Matsuda K, Truong N, Lee A, Chun C, Cheng SY, Korc M. Pancreatic cancer cell-derived vascular endothelial growth factor is biologically active in vitro and enhances tumorigenicity in vivo. International Journal of Cancer. 92: 361-9. PMID 11291072 DOI: 10.1002/Ijc.1202  0.445
2001 Gaubert F, Escaffit F, Bertrand C, Korc M, Pradayrol L, Clemente F, Estival A. Expression of the high molecular weight fibroblast growth factor-2 isoform of 210 amino acids is associated with modulation of protein kinases C delta and epsilon and ERK activation. The Journal of Biological Chemistry. 276: 1545-54. PMID 11031252 DOI: 10.1074/Jbc.M001184200  0.365
2001 Itakura J, Tang R, Aikawa T, Fujii H, Korc M, Matsumoto Y. Overexpression of lymphangiogenic growth factor VEGF-C in human pancreatic cancer European Journal of Cancer. 37: S40. DOI: 10.1016/S0959-8049(01)80627-4  0.334
2000 Conejo JR, Kleeff J, Koliopanos A, Matsuda K, Zhu ZW, Goecke H, Bicheng N, Zimmermann A, Korc M, Friess H, Büchler MW. Syndecan-1 expression is up-regulated in pancreatic but not in other gastrointestinal cancers. International Journal of Cancer. 88: 12-20. PMID 10962434 DOI: 10.1002/1097-0215(20001001)88:1<12::Aid-Ijc3>3.0.Co;2-T  0.52
2000 Wang L, Friess H, Zhu Z, Frigeri L, Zimmermann A, Korc M, Berberat PO, Büchler MW. Galectin-1 and galectin-3 in chronic pancreatitis. Laboratory Investigation; a Journal of Technical Methods and Pathology. 80: 1233-41. PMID 10950114 DOI: 10.1038/Labinvest.3780131  0.373
2000 Zhu Z, Kleeff J, Friess H, Wang L, Zimmermann A, Yarden Y, Büchler MW, Korc M. Epiregulin is Up-regulated in pancreatic cancer and stimulates pancreatic cancer cell growth. Biochemical and Biophysical Research Communications. 273: 1019-24. PMID 10891365 DOI: 10.1006/Bbrc.2000.3033  0.527
2000 Kleeff J, Kornmann M, Sawhney H, Korc M. Actinomycin D induces apoptosis and inhibits growth of pancreatic cancer cells. International Journal of Cancer. 86: 399-407. PMID 10760829 DOI: 10.1002/(Sici)1097-0215(20000501)86:3<399::Aid-Ijc15>3.0.Co;2-G  0.474
2000 Lopez ME, Korc M. A novel type I fibroblast growth factor receptor activates mitogenic signaling in the absence of detectable tyrosine phosphorylation of FRS2. Journal of Biological Chemistry. 275: 15933-15939. PMID 10748122 DOI: 10.1074/Jbc.M909299199  0.324
2000 Kornmann M, Ishiwata T, Kleeff J, Beger HG, Korc M. Fas and Fas-ligand expression in human pancreatic cancer. Annals of Surgery. 231: 368-79. PMID 10714630 DOI: 10.1097/00000658-200003000-00010  0.445
2000 Kornmann M, Ishiwata T, Maruyama H, Beger HG, Korc M. Coexpression of FAS and FAS-ligand in chronic pancreatitis: correlation with apoptosis. Pancreas. 20: 123-8. PMID 10707926 DOI: 10.1097/00006676-200003000-00003  0.37
2000 Friess H, Wang L, Zhu Z, Gerber R, Schröder M, Fukuda A, Zimmermann A, Korc M, Büchler MW. Growth factor receptors are differentially expressed in cancers of the papilla of vater and pancreas. Annals of Surgery. 230: 767-74; discussion 7. PMID 10615931 DOI: 10.1097/00000658-199912000-00005  0.493
2000 Itakura J, Ishiwata T, Shen B, Kornmann M, Korc M. Concomitant over-expression of vascular endothelial growth factor and its receptors in pancreatic cancer. International Journal of Cancer. 85: 27-34. PMID 10585578 DOI: 10.1002/(Sici)1097-0215(20000101)85:1<27::Aid-Ijc5>3.0.Co;2-8  0.483
2000 Wagner M, Kleeff J, Friess H, Büchler MW, Korc M. Enhanced expression of the type II transforming growth factor-beta receptor is associated with decreased survival in human pancreatic cancer. Pancreas. 19: 370-6. PMID 10547197 DOI: 10.1097/00006676-199911000-00008  0.488
2000 Friess H, Kleeff J, Korc M, Büchler MW. Molecular aspects of pancreatic cancer and future perspectives. Digestive Surgery. 16: 281-90. PMID 10449972 DOI: 10.1159/000018737  0.405
2000 Xu Z, Friess H, Aebi S, Korc M, Kleeff JH, Buchler MW. Increased sensitivity to gemcitabine following Bcl-xL antisense treatment in pancreatic cancer cells Gastroenterology. 118: A521. DOI: 10.1016/S0016-5085(00)84211-0  0.35
2000 Lopez ME, Korc M. Novel type I fibroblast growth factor receptor in pancreatic cancer Gastroenterology. 118: A183. DOI: 10.1016/S0016-5085(00)82806-1  0.368
1999 Zhu Z, Friess H, diMola FF, Zimmermann A, Graber HU, Korc M, Büchler MW. Nerve growth factor expression correlates with perineural invasion and pain in human pancreatic cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 17: 2419-28. PMID 10561305 DOI: 10.1200/Jco.1999.17.8.2419  0.462
1999 Friess H, Fukuda A, Tang WH, Eichenberger A, Furlan N, Zimmermann A, Korc M, Büchler MW. Concomitant analysis of the epidermal growth factor receptor family in esophageal cancer: overexpression of epidermal growth factor receptor mRNA but not of c-erbB-2 and c-erbB-3. World Journal of Surgery. 23: 1010-8. PMID 10512940 DOI: 10.1007/S002689900616  0.422
1999 Kleeff J, Wildi S, Kumbasar A, Friess H, Lander AD, Korc M. Stable transfection of a glypican-1 antisense construct decreases tumorigenicity in PANC-1 pancreatic carcinoma cells. Pancreas. 19: 281-8. PMID 10505759 DOI: 10.1097/00006676-199910000-00009  0.425
1999 Kleeff J, Friess H, Simon P, Susmallian S, Büchler P, Zimmermann A, Büchler MW, Korc M. Overexpression of Smad2 and colocalization with TGF-beta1 in human pancreatic cancer. Digestive Diseases and Sciences. 44: 1793-802. PMID 10505717 DOI: 10.1023/A:1018882320500  0.427
1999 Kleeff J, Ishiwata T, Maruyama H, Friess H, Truong P, Büchler MW, Falb D, Korc M. The TGF-beta signaling inhibitor Smad7 enhances tumorigenicity in pancreatic cancer. Oncogene. 18: 5363-72. PMID 10498890 DOI: 10.1038/Sj.Onc.1202909  0.412
1999 Maruyama H, Kleeff J, Wildi S, Friess H, Büchler MW, Israel MA, Korc M. Id-1 and Id-2 are overexpressed in pancreatic cancer and in dysplastic lesions in chronic pancreatitis. The American Journal of Pathology. 155: 815-22. PMID 10487839 DOI: 10.1016/S0002-9440(10)65180-2  0.509
1999 Kornmann M, Tangvoranuntakul P, Korc M. TGF-β-1 up-regulates cyclin D1 expression in colo-357 cells, whereas suppression of cyclin D1 levels is associated with down-regulation of the type I TGF-β receptor International Journal of Cancer. 83: 247-254. PMID 10471535 DOI: 10.1002/(Sici)1097-0215(19991008)83:2<247::Aid-Ijc17>3.0.Co;2-0  0.366
1999 Graber HU, Friess H, Zimmermann A, Korc M, Adler G, Schmid R, Büchler MW. Bak expression and cell death occur in peritumorous tissue but not in pancreatic cancer cells. Journal of Gastrointestinal Surgery : Official Journal of the Society For Surgery of the Alimentary Tract. 3: 74-80; discussion 81. PMID 10457328 DOI: 10.1016/S1091-255X(99)80012-2  0.476
1999 Kleeff J, Wildi S, Friess H, Korc M. Ligand induced upregulation of the type II transforming growth factor (TGF-beta) receptor enhances TGF-beta responsiveness in COLO-357 cells. Pancreas. 18: 364-70. PMID 10231841 DOI: 10.1097/00006676-199905000-00006  0.339
1999 Kleeff J, Kusama T, Rossi DL, Ishiwata T, Maruyama H, Friess H, Büchler MW, Zlotnik A, Korc M. Detection and localization of Mip-3alpha/LARC/Exodus, a macrophage proinflammatory chemokine, and its CCR6 receptor in human pancreatic cancer. International Journal of Cancer. 81: 650-7. PMID 10225458 DOI: 10.1002/(Sici)1097-0215(19990517)81:4<650::Aid-Ijc23>3.0.Co;2-#  0.412
1999 Kleeff J, Maruyama H, Ishiwata T, Sawhney H, Friess H, Büchler MW, Korc M. Bone morphogenetic protein 2 exerts diverse effects on cell growth in vitro and is expressed in human pancreatic cancer in vivo. Gastroenterology. 116: 1202-16. PMID 10220513 DOI: 10.1016/S0016-5085(99)70024-7  0.373
1999 Abou-Shady M, Baer HU, Friess H, Berberat P, Zimmermann A, Graber H, Gold LI, Korc M, Büchler MW. Transforming growth factor betas and their signaling receptors in human hepatocellular carcinoma. American Journal of Surgery. 177: 209-15. PMID 10219856 DOI: 10.1016/S0002-9610(99)00012-4  0.307
1999 Ebert M, Yokoyama M, Ishiwata T, Friess H, Büchler MW, Malfertheiner P, Korc M. Alteration of fibroblast growth factor and receptor expression after acute pancreatitis in humans. Pancreas. 18: 240-6. PMID 10206481 DOI: 10.1097/00006676-199904000-00004  0.307
1999 Bristow RE, Baldwin RL, Yamada SD, Korc M, Karlan BY. Altered expression of transforming growth factor-β ligands and receptors in primary and recurrent ovarian carcinoma Cancer. 85: 658-668. PMID 10091739 DOI: 10.1002/(Sici)1097-0142(19990201)85:3<658::Aid-Cncr16>3.0.Co;2-M  0.333
1999 Kleeff J, Maruyama H, Friess H, Büchler MW, Falb D, Korc M. Smad6 suppresses TGF-beta-induced growth inhibition in COLO-357 pancreatic cancer cells and is overexpressed in pancreatic cancer. Biochemical and Biophysical Research Communications. 255: 268-73. PMID 10049697 DOI: 10.1006/Bbrc.1999.0171  0.446
1999 Graber HU, Friess H, Kaufmann B, Willi D, Zimmermann A, Korc M, Büchler MW. ErbB-4 mRNA expression is decreased in non-metastatic pancreatic cancer. International Journal of Cancer. Journal International Du Cancer. 84: 24-7. PMID 9988227 DOI: 10.1002/(Sici)1097-0215(19990219)84:1<24::Aid-Ijc5>3.0.Co;2-2  0.527
1998 Friess H, Lu Z, Graber HU, Zimmermann A, Adler G, Korc M, Schmid RM, Büchler MW. bax, but not bcl-2, influences the prognosis of human pancreatic cancer. Gut. 43: 414-21. PMID 9863489 DOI: 10.1136/Gut.43.3.414  0.471
1998 Guo XZ, Friess H, Di Mola FF, Heinicke JM, Abou-Shady M, Graber HU, Baer HU, Zimmermann A, Korc M, Büchler MW. KAI1, a new metastasis suppressor gene, is reduced in metastatic hepatocellular carcinoma. Hepatology (Baltimore, Md.). 28: 1481-8. PMID 9828210 DOI: 10.1002/Hep.510280606  0.341
1998 Kleeff J, Ishiwata T, Kumbasar A, Friess H, Büchler MW, Lander AD, Korc M. The cell-surface heparan sulfate proteoglycan glypican-1 regulates growth factor action in pancreatic carcinoma cells and is overexpressed in human pancreatic cancer. The Journal of Clinical Investigation. 102: 1662-73. PMID 9802880 DOI: 10.1172/Jci4105  0.53
1998 Ishiwata T, Kornmann M, Beger HG, Korc M. Enhanced fibroblast growth factor 5 expression in stromal and exocrine elements of the pancreas in chronic pancreatitis. Gut. 43: 134-9. PMID 9771418 DOI: 10.1136/Gut.43.1.134  0.374
1998 Wagner M, Kleeff J, Lopez ME, Bockman I, Massaqué J, Korc M. Transfection of the type I TGF-beta receptor restores TGF-beta responsiveness in pancreatic cancer. International Journal of Cancer. 78: 255-60. PMID 9754660 DOI: 10.1002/(Sici)1097-0215(19981005)78:2<255::Aid-Ijc21>3.0.Co;2-8  0.361
1998 Kleeff J, Ishiwata T, Friess H, Büchler MW, Korc M. Concomitant over-expression of activin/inhibin beta subunits and their receptors in human pancreatic cancer. International Journal of Cancer. 77: 860-8. PMID 9714055 DOI: 10.1002/(Sici)1097-0215(19980911)77:6<860::Aid-Ijc11>3.0.Co;2-5  0.528
1998 Maurer CA, Friess H, Kretschmann B, Zimmermann A, Stauffer A, Baer HU, Korc M, Büchler MW. Increased expression of erbB3 in colorectal cancer is associated with concomitant increase in the level of erbB2. Human Pathology. 29: 771-7. PMID 9712416 DOI: 10.1016/S0046-8177(98)90444-0  0.485
1998 Kornmann M, Beger HG, Korc M. Role of fibroblast growth factors and their receptors in pancreatic cancer and chronic pancreatitis. Pancreas. 17: 169-75. PMID 9700949 DOI: 10.1097/00006676-199808000-00010  0.367
1998 Friess H, Guo XZ, Berberat P, Graber HU, Zimmermann A, Korc M, Büchler MW. Reduced KAI1 expression in pancreatic cancer is associated with lymph node and distant metastases. International Journal of Cancer. Journal International Du Cancer. 79: 349-55. PMID 9699525 DOI: 10.1002/(Sici)1097-0215(19980821)79:4<349::Aid-Ijc7>3.0.Co;2-V  0.397
1998 Ishiwata T, Friess H, Büchler MW, Lopez ME, Korc M. Characterization of keratinocyte growth factor and receptor expression in human pancreatic cancer. The American Journal of Pathology. 153: 213-22. PMID 9665482 DOI: 10.1016/S0002-9440(10)65562-9  0.466
1998 Kornmann M, Ishiwata T, Itakura J, Tangvoranuntakul P, Beger HG, Korc M. Increased cyclin D1 in human pancreatic cancer is associated with decreased postoperative survival Oncology. 55: 363-369. PMID 9663429 DOI: 10.1159/000011879  0.322
1998 Kleeff J, Korc M. Up-regulation of transforming growth factor (TGF)-beta receptors by TGF-beta1 in COLO-357 cells. The Journal of Biological Chemistry. 273: 7495-500. PMID 9516449 DOI: 10.1074/Jbc.273.13.7495  0.381
1998 Wagner M, Lopez ME, Cahn M, Korc M. Suppression of fibroblast growth factor receptor signaling inhibits pancreatic cancer growth in vitro and in vivo. Gastroenterology. 114: 798-807. PMID 9516401 DOI: 10.1016/S0016-5085(98)70594-3  0.498
1998 Friess H, Lu Z, Riesle E, Uhl W, Bründler AM, Horvath L, Gold LI, Korc M, Büchler MW. Enhanced expression of TGF-betas and their receptors in human acute pancreatitis. Annals of Surgery. 227: 95-104. PMID 9445116 DOI: 10.1097/00000658-199801000-00014  0.37
1998 Kornmann M, Arber N, Korc M. Inhibition of basal and mitogen-stimulated pancreatic cancer cell growth by cyclin D1 antisense is associated with loss of tumorigenicity and potentiation of cytotoxicity to cisplatinum. The Journal of Clinical Investigation. 101: 344-52. PMID 9435306 DOI: 10.1172/Jci1323  0.478
1998 Korc M. Role of Growth Factors in Pancreatic Cancer Surgical Oncology Clinics of North America. 7: 25-41. DOI: 10.1016/S1055-3207(18)30283-7  0.489
1998 Friess H, Duarte R, Kleeff J, Fukuda A, Tang W, Graber H, Schilling M, Zimmermann A, Korc M, Büchler MW. The plasminogen activator/plasmin system is up-regulated after acute necrotizing pancreatitis in human beings Surgery. 124: 79-86. DOI: 10.1016/S0039-6060(98)70078-9  0.407
1998 Ebert M, Yokoyama M, Ishiwata T, Friess H, Büchler M, Malfertheiner P, Korc M. Alteration of fibroblast growth factor expression following acute pancreatitis Gastroenterology. 114: A455. DOI: 10.1016/S0016-5085(98)81838-6  0.304
1997 Lu Z, Friess H, Graber HU, Guo X, Schilling M, Zimmermann A, Korc M, Büchler MW. Presence of two signaling TGF-beta receptors in human pancreatic cancer correlates with advanced tumor stage. Digestive Diseases and Sciences. 42: 2054-63. PMID 9365135 DOI: 10.1023/A:1018814416903  0.352
1997 Ishiwata T, Bergmann U, Kornmann M, Lopez M, Beger HG, Korc M. Altered expression of insulin-like growth factor II receptor in human pancreatic cancer. Pancreas. 15: 367-73. PMID 9361090 DOI: 10.1097/00006676-199711000-00006  0.404
1997 Kornmann M, Ishiwata T, Beger HG, Korc M. Fibroblast growth factor-5 stimulates mitogenic signaling and is overexpressed in human pancreatic cancer: evidence for autocrine and paracrine actions. Oncogene. 15: 1417-24. PMID 9333017 DOI: 10.1038/Sj.Onc.1201307  0.513
1997 Hsiang D, Friess H, Büchler MW, Ebert M, Butler J, Korc M. Absence of K-ras mutations in the pancreatic parenchyma of patients with chronic pancreatitis. American Journal of Surgery. 174: 242-6. PMID 9324130 DOI: 10.1016/S0002-9610(97)00133-5  0.314
1997 Funatomi H, Itakura J, Ishiwata T, Pastan I, Thompson SA, Johnson GR, Korc M. Amphiregulin antisense oligonucleotide inhibits the growth of T3M4 human pancreatic cancer cells and sensitizes the cells to EGF receptor-targeted therapy. International Journal of Cancer. 72: 512-7. PMID 9247297 DOI: 10.1002/(Sici)1097-0215(19970729)72:3<512::Aid-Ijc21>3.0.Co;2-C  0.518
1997 Naef M, Ishiwata T, Friess H, Büchler MW, Gold LI, Korc M. Differential localization of transforming growth factor‐β isoforms in human gastric mucosa and overexpression in gastric carcinoma International Journal of Cancer. 71: 131-137. PMID 9139831 DOI: 10.1002/(Sici)1097-0215(19970410)71:2<131::Aid-Ijc1>3.0.Co;2-1  0.346
1997 Cantero D, Friess H, Deflorin J, Zimmermann A, Bründler MA, Riesle E, Korc M, Büchler MW. Enhanced expression of urokinase plasminogen activator and its receptor in pancreatic carcinoma. British Journal of Cancer. 75: 388-95. PMID 9020484 DOI: 10.1038/Bjc.1997.63  0.496
1996 Bergmann U, Funatomi H, Kornmann M, Ishiwata T, Beger H, Korc M. Insulin-like growth factor II activates mitogenic signaling in pancreatic cancer cells via IRS-1. International Journal of Oncology. 9: 487-92. PMID 21541539 DOI: 10.3892/ijo.9.3.487  0.307
1996 Wagner M, Cao T, Lopez ME, Hope C, van Nostrand K, Kobrin MS, Fan HU, Büchler MW, Korc M. Expression of a truncated EGF receptor is associated with inhibition of pancreatic cancer cell growth and enhanced sensitivity to cisplatinum. International Journal of Cancer. 68: 782-7. PMID 8980184 DOI: 10.1002/(Sici)1097-0215(19961211)68:6<782::Aid-Ijc16>3.0.Co;2-2  0.464
1996 Friess H, Berberat P, Schilling M, Kunz J, Korc M, Büchler MW. Pancreatic cancer: the potential clinical relevance of alterations in growth factors and their receptors. Journal of Molecular Medicine (Berlin, Germany). 74: 35-42. PMID 8834768 DOI: 10.1007/BF00202070  0.376
1996 Lopez ME, Kobrin MS, Moriai T, Yokoyama M, Friess H, Büchler M, Korc M. Single-strand conformation polymorphism analysis of the epidermal growth factor receptor at codon 497. Pancreas. 12: 216-20. PMID 8830326 DOI: 10.1097/00006676-199604000-00002  0.349
1996 Baldwin RL, Kobrin MS, Tran T, Pastan I, Korc M. Cytotoxic effects of TGF-α-Pseudomonas exotoxin A fusion protein in human pancreatic carcinoma cells Pancreas. 13: 16-21. PMID 8783329 DOI: 10.1097/00006676-199607000-00002  0.412
1996 Baldwin RL, Friess H, Yokoyama M, Lopez ME, Kobrin MS, Büchler MW, Korc M. Attenuated ALK5 receptor expression in human pancreatic cancer: Correlation with resistance to growth inhibition International Journal of Cancer. 67: 283-288. PMID 8760600 DOI: 10.1002/(Sici)1097-0215(19960717)67:2<283::Aid-Ijc21>3.0.Co;2-B  0.39
1996 Visser CJ, de Weger RA, van Blokland WT, Seifert-Bock I, Kobrin MS, Korc M, Woutersen RA. Epidermal growth factor receptor expression in pancreatic lesions induced in the rat by azaserine. British Journal of Cancer. 74: 92-8. PMID 8679465 DOI: 10.1038/Bjc.1996.321  0.409
1996 Visser CJ, Bruggink AH, Korc M, Kobrin MS, de Weger RA, Seifert-Bock I, van Blokland WT, van Garderen-Hoetmer A, Woutersen RA. Overexpression of transforming growth factor-alpha and epidermal growth factor receptor, but not epidermal growth factor, in exocrine pancreatic tumours in hamsters. Carcinogenesis. 17: 779-85. PMID 8625491 DOI: 10.1093/Carcin/17.4.779  0.395
1996 Estival A, Monzat V, Miquel K, Gaubert F, Hollande E, Korc M, Vaysse N, Clemente F. Differential regulation of fibroblast growth factor (FGF) receptor-1 mRNA and protein by two molecular forms of basic FGF. Modulation of FGFR-1 mRNA stability. Journal of Biological Chemistry. 271: 5663-5670. PMID 8621430 DOI: 10.1074/Jbc.271.10.5663  0.406
1996 Naef M, Yokoyama M, Friess H, Büchler MW, Korc M. Co-expression of heparin-binding EGF-like growth factor and related peptides in human gastric carcinoma. International Journal of Cancer. 66: 315-21. PMID 8621250 DOI: 10.1002/(Sici)1097-0215(19960503)66:3<315::Aid-Ijc8>3.0.Co;2-1  0.425
1996 Bergmann U, Funatomi H, Kornmann M, Beger HG, Korc M. Increased expression of insulin receptor substrate-1 in human pancreatic cancer. Biochemical and Biophysical Research Communications. 220: 886-90. PMID 8607861 DOI: 10.1006/Bbrc.1996.0500  0.457
1995 Ebert M, Yokoyama M, Friess H, Kobrin MS, Büchler MW, Korc M. Induction of platelet-derived growth factor A and B chains and over-expression of their receptors in human pancreatic cancer. International Journal of Cancer. 62: 529-35. PMID 7665222 DOI: 10.1002/Ijc.2910620507  0.447
1995 Bruner KL, Rodgers WH, Gold LI, Korc M, Hargrove JT, Matrisian LM, Osteen KG. Transforming growth factor β mediates the progesterone suppression of an epithelial metalloproteinase by adjacent stroma in the human endometrium Proceedings of the National Academy of Sciences of the United States of America. 92: 7362-7366. PMID 7638197 DOI: 10.1073/Pnas.92.16.7362  0.321
1995 Ebert M, Friess H, Büchler MW, Korc M. Differential distribution of human epidermal growth factor receptor family in acute pancreatitis. Digestive Diseases and Sciences. 40: 2134-42. PMID 7587780 DOI: 10.1007/Bf02208997  0.431
1995 Siddiqi I, Funatomi H, Kobrin MS, Friess H, Büchler MW, Korc M. Increased expression of keratinocyte growth factor in human pancreatic cancer. Biochemical and Biophysical Research Communications. 215: 309-15. PMID 7575607 DOI: 10.1006/Bbrc.1995.2467  0.521
1995 Deflorin J, Friess H, Schmid R, Horvath L, Korc M, Adler G, Büchler M. Enhanced expression of apoptotic factors implicate a role in human pancreatic cancer Gastroenterology. 108: A349. DOI: 10.1016/0016-5085(95)24055-1  0.366
1994 Friess H, Yamanaka Y, Büchler M, Kobrin MS, Tahara E, Korc M. Cripto, a member of the epidermal growth factor family, is over-expressed in human pancreatic cancer and chronic pancreatitis. International Journal of Cancer. 56: 668-74. PMID 8314343 DOI: 10.1002/Ijc.2910560511  0.543
1994 Friess H, Yamanaka Y, Büchler M, Ebert M, Beger HG, Gold LI, Korc M. Enhanced expression of transforming growth factor beta isoforms in pancreatic cancer correlates with decreased survival. Gastroenterology. 105: 1846-56. PMID 8253361 DOI: 10.1016/0016-5085(93)91084-U  0.414
1994 Kobrin MS, Funatomi H, Friess H, Buchler MW, Stathis P, Korc M. Induction and expression of heparin-binding EGF-like growth factor in human pancreatic cancer. Biochemical and Biophysical Research Communications. 202: 1705-9. PMID 8060360 DOI: 10.1006/bbrc.1994.2131  0.439
1994 Korc M, Friess H, Yamanaka Y, Kobrin MS, Buchler M, Beger HG. Chronic pancreatitis is associated with increased concentrations of epidermal growth factor receptor, transforming growth factor alpha, and phospholipase C gamma. Gut. 35: 1468-73. PMID 7959207 DOI: 10.1136/Gut.35.10.1468  0.409
1994 Moriai T, Kobrin MS, Hope C, Speck L, Korc M. A variant epidermal growth factor receptor exhibits altered type alpha transforming growth factor binding and transmembrane signaling. Proceedings of the National Academy of Sciences of the United States of America. 91: 10217-21. PMID 7937865 DOI: 10.1073/Pnas.91.21.10217  0.356
1994 Longnecker DS, Pour PM, Scarpelli DG, Caldas C, Redston MS, Hahn SA, Seymour AB, Hruban RH, Yeo CJ, Kern SE, Ruggeri BA, Klein-Szanto AJP, Huang LY, Lang D, Andr’en-Sandberg Å, ... ... Korc M, et al. Investigational strategies for detection and intervention in early-stage pancreatic cancer International Journal of Pancreatology. 16: 183-310. PMID 7868945 DOI: 10.1007/Bf02944330  0.346
1994 Friess H, Yamanaka Y, Büchler M, Hammer K, Kobrin MS, Beger HG, Korc M. A subgroup of patients with chronic pancreatitis overexpress the c-erb B-2 protooncogene. Annals of Surgery. 220: 183-92. PMID 7519839 DOI: 10.1097/00000658-199408000-00010  0.322
1994 Gold LI, Korc M. Expression of Transforming Growth Factor-β1, 2, and 3 m RNAand Protein in Human Cancers Digestive Surgery. 11: 150-156. DOI: 10.1159/000172246  0.361
1994 Korc M, Friess H, Kobrin MS, Ebert M, Büchler MW. Growth Factors in Human Pancreatic Cancer: Update on the Role of the Epidermal Growth Factor Receptor Digestive Surgery. 11: 147-149. DOI: 10.1159/000172245  0.448
1993 Casey G, Yamanaka Y, Friess H, Kobrin MS, Lopez ME, Buchler M, Beger HG, Korc M. p53 mutations are common in pancreatic cancer and are absent in chronic pancreatitis. Cancer Letters. 69: 151-60. PMID 8513440 DOI: 10.1016/0304-3835(93)90168-9  0.428
1993 Moriai T, Kobrin MS, Korc M. Cloning of a variant epidermal growth factor receptor. Biochemical and Biophysical Research Communications. 191: 1034-9. PMID 8466482 DOI: 10.1006/Bbrc.1993.1321  0.448
1993 Baldwin RL, Korc M. Growth inhibition of human pancreatic carcinoma cells by transforming growth factor beta-1. Growth Factors (Chur, Switzerland). 8: 23-34. PMID 8383514 DOI: 10.3109/08977199309029131  0.408
1993 Korc M. Islet growth factors: curing diabetes and preventing chronic pancreatitis? The Journal of Clinical Investigation. 92: 1113-4. PMID 8376573 DOI: 10.1172/Jci116677  0.336
1993 Yamanaka Y, Friess H, Kobrin MS, Büchler M, Kunz J, Beger HG, Korc M. Overexpression of HER2/neu oncogene in human pancreatic carcinoma. Human Pathology. 24: 1127-34. PMID 8104858 DOI: 10.1016/0046-8177(93)90194-L  0.431
1992 Korc M. Growth factors and pancreatic cancer. International Journal of Pancreatology : Official Journal of the International Association of Pancreatology. 9: 87-91. PMID 1744452 DOI: 10.1007/Bf02925583  0.466
1992 Korc M, Chandrasekar B, Yamanaka Y, Friess H, Buchier M, Beger HG. Overexpression of the epidermal growth factor receptor in human pancreatic cancer is associated with concomitant increases in the levels of epidermal growth factor and transforming growth factor alpha. The Journal of Clinical Investigation. 90: 1352-60. PMID 1401070 DOI: 10.1172/Jci116001  0.442
1991 Korc M. Potential role of the epidermal growth factor receptor in human pancreatic cancer. International Journal of Pancreatology : Official Journal of the International Association of Pancreatology. 7: 71-81. PMID 2081930 DOI: 10.1007/Bf02924222  0.403
1991 Chandrasekar B, Korc M. Basic fibroblast growth factor is a calcium-mobilizing secretagogue in rat pancreatic acini. Biochemical and Biophysical Research Communications. 177: 166-170. PMID 1710445 DOI: 10.1016/0006-291X(91)91963-D  0.367
1990 Garewal H, Meltzer P, Trent J, Prabhala R, Sampliner R, Korc M. Epidermal growth factor receptor overexpression and trisomy 7 in a case of Barrett's esophagus. Digestive Diseases and Sciences. 35: 1115-20. PMID 2390926 DOI: 10.1007/Bf01537584  0.378
1990 Raitano AB, Scuderi P, Korc M. Long-term effect of tumor necrosis factor and gamma interferon in human pancreatic carcinoma cells. International Journal of Pancreatology. 6: 109-118. PMID 2121855 DOI: 10.1007/Bf02933045  0.372
1990 Chang S, Brannon PM, Korc M. Effects of dietary manganese deficiency on rat pancreatic amylase mRNA levels. Journal of Nutrition. 120: 1228-1234. PMID 1698952 DOI: 10.1093/Jn/120.10.1228  0.307
1989 Ackerman MS, Roeske WR, Heck RJ, Korc M. Identification and characterization of muscarinic receptors in cultured human pancreatic carcinoma cells Pancreas. 4: 363-370. PMID 2734280 DOI: 10.1097/00006676-198906000-00014  0.362
1989 Morisset J, Larose L, Korc M. Epidermal Growth Factor Inhibits Rat Pancreatic Cell Proliferation, Causes Acinar Cell Hypertrophy, and Prevents Caerulein-Induced Desensitization of Amylase Release* Endocrinology. 124: 2693-2698. PMID 2470581 DOI: 10.1210/Endo-124-6-2693  0.38
1988 Komm BS, Terpening CM, Benz DJ, Graeme KA, Gallegos A, Korc M, Greene GL, O'Malley BW, Haussler MR. Estrogen binding, receptor mRNA, and biologic response in osteoblast-like osteosarcoma cells. Science (New York, N.Y.). 241: 81-4. PMID 3164526 DOI: 10.1126/Science.3164526  0.339
1988 BIRCH M, MEYSKENS F, KORC M. Protein Kinase C and Melanocyte Transformation Pigment Cell Research. 1: 163-168. DOI: 10.1111/J.1600-0749.1988.Tb00808.X  0.351
1987 Smith JJ, Derynck R, Korc M. Production of transforming growth factor alpha in human pancreatic cancer cells: evidence for a superagonist autocrine cycle. Proceedings of the National Academy of Sciences of the United States of America. 84: 7567-70. PMID 3499610 DOI: 10.1073/Pnas.84.21.7567  0.39
1987 Brockenbrough JS, Korc M. Effects of 1-oleoyl-2-acetyl glycerol are distinct from those of phorbol ester in rat pancreatic acini. Life Sciences. 40: 1625-1631. PMID 2436020 DOI: 10.1016/0024-3205(87)90129-9  0.365
1987 Brannon PM, Collins VP, Korc M. Alterations of pancreatic digestive enzyme content in the manganese-deficient rat. The Journal of Nutrition. 117: 305-11. PMID 2435870 DOI: 10.1093/Jn/117.2.305  0.324
1986 Rao RK, Thornburg W, Korc M, Matrisian LM, Magun BE, Koldovský O. Processing of epidermal growth factor by suckling and adult rat intestinal cells. The American Journal of Physiology. 250: G850-5. PMID 3521322 DOI: 10.1152/Ajpgi.1986.250.6.G850  0.324
1986 Korc M, Meltzer P, Trent J. Enhanced expression of epidermal growth factor receptor correlates with alterations of chromosome 7 in human pancreatic cancer Proceedings of the National Academy of Sciences of the United States of America. 83: 5141-5144. PMID 3014534 DOI: 10.1073/Pnas.83.14.5141  0.408
1986 Hazlett D, Korc M, Brannon PM. Effects of malnutrition and chronic reserpine treatment on pancreatic exocrine function. Pediatric Research. 20: 1236-1239. PMID 2432455 DOI: 10.1203/00006450-198612000-00009  0.317
1986 Brannon PM, Demarest AS, Sabb JE, Korc M. Dietary modulation of epidermal growth factor action in cultured pancreatic acinar cells of the rat. Journal of Nutrition. 116: 1306-1315. PMID 2427673 DOI: 10.1093/Jn/116.7.1306  0.364
1985 Korc M, Magun BE. Residual inhibition of epidermal growth factor binding by pancreatic secretagogues and phorbol ester in rat pancreas. Journal of Cellular Physiology. 124: 344-348. PMID 3876345 DOI: 10.1002/Jcp.1041240226  0.356
1985 Korc M, Magun BE. Binding and processing of epidermal growth factor in Panc-I human pancreatic carcinoma cells. Life Sciences. 36: 1849-1855. PMID 2985903 DOI: 10.1016/0024-3205(85)90158-4  0.395
1984 Korc M, Matrisian LM, Magun BE. Cytosolic calcium regulates epidermal growth factor endocytosis in rat pancreas and cultured fibroblasts. Proceedings of the National Academy of Sciences of the United States of America. 81: 461-5. PMID 6320188 DOI: 10.1073/Pnas.81.2.461  0.388
1984 Korc M, Matrisian LM, Nakamura R, Magun BE. Epidermal growth factor binding is altered in pancreatic acini from diabetic rats. Life Sciences. 35: 2049-55. PMID 6092811 DOI: 10.1016/0024-3205(84)90562-9  0.313
1983 Korc M, Matrisian LM, Magun BE. Direct modulation of epidermal growth factor binding by cholecystokinin. Life Sciences. 33: 561-8. PMID 6310297 DOI: 10.1016/0024-3205(83)90131-5  0.333
1983 Korc M, Matrisian LM, Planck SR, Magun BE. Binding of epidermal growth factor in rat pancreatic acini Biochemical and Biophysical Research Communications. 111: 1066-1073. PMID 6301480 DOI: 10.1016/0006-291X(83)91408-0  0.362
Low-probability matches (unlikely to be authored by this person)
2011 Preis M, Gardner TB, Gordon SR, Pipas JM, Mackenzie TA, Klein EE, Longnecker DS, Gutmann EJ, Sempere LF, Korc M. MicroRNA-10b expression correlates with response to neoadjuvant therapy and survival in pancreatic ductal adenocarcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 5812-21. PMID 21652542 DOI: 10.1158/1078-0432.CCR-11-0695  0.3
2012 Kerley-Hamilton JS, Trask HW, Ridley CJ, Dufour E, Lesseur C, Ringelberg CS, Moodie KL, Shipman SL, Korc M, Gui J, Shworak NW, Tomlinson CR. Inherent and benzo[a]pyrene-induced differential aryl hydrocarbon receptor signaling greatly affects life span, atherosclerosis, cardiac gene expression, and body and heart growth in mice. Toxicological Sciences : An Official Journal of the Society of Toxicology. 126: 391-404. PMID 22228805 DOI: 10.1093/Toxsci/Kfs002  0.299
1991 Knight SA, Kohr W, Korc M. Manganese-stimulated phosphorylation of a rat pancreatic protein: identity with elongation factor 2. Biochimica Et Biophysica Acta. 1092: 196-204. PMID 2018786 DOI: 10.1016/0167-4889(91)90157-S  0.299
2013 Wang Z, Ali S, Banerjee S, Bao B, Li Y, Azmi AS, Korc M, Sarkar FH. Activated K-Ras and INK4a/Arf deficiency promote aggressiveness of pancreatic cancer by induction of EMT consistent with cancer stem cell phenotype. Journal of Cellular Physiology. 228: 556-62. PMID 22806240 DOI: 10.1002/Jcp.24162  0.297
2016 Kleeff J, Korc M, Apte M, La Vecchia C, Johnson CD, Biankin AV, Neale RE, Tempero M, Tuveson DA, Hruban RH, Neoptolemos JP. Pancreatic cancer. Nature Reviews. Disease Primers. 2: 16022. PMID 27158978 DOI: 10.1038/nrdp.2016.22  0.296
2001 Lu Z, Kleeff J, Shrikhande S, Zimmermann T, Korc M, Friess H, Büchler MW. Expression of the multidrug-resistance 1 (MDR1) gene and prognosis in human pancreatic cancer. Pancreas. 21: 240-7. PMID 11039467 DOI: 10.1097/00006676-200010000-00004  0.294
1999 di Mola FF, Friess H, Scheuren A, Di Sebastiano P, Graber H, Egger B, Zimmermann A, Korc M, Büchler MW. Transforming growth factor-betas and their signaling receptors are coexpressed in Crohn's disease. Annals of Surgery. 229: 67-75. PMID 9923802 DOI: 10.1097/00000658-199901000-00009  0.293
2002 Kleeff J, Shi X, Bode HP, Hoover K, Shrikhande S, Bryant PJ, Korc M, Büchler MW, Friess H. Altered expression and localization of the tight junction protein ZO-1 in primary and metastatic pancreatic cancer. Pancreas. 23: 259-65. PMID 11590321 DOI: 10.1097/00006676-200110000-00006  0.293
2016 Gore AJ, Deitz SL, Palam LR, Craven KE, Korc M. Pancreatic cancer-associated retinoblastoma 1 dysfunction enables TGF-β to promote proliferation. The Journal of Clinical Investigation. 126: 2774. PMID 27367186 DOI: 10.1172/JCI88840  0.289
2007 Formentini A, Prokopchuk O, Leder G, Straeter J, Kleeff J, Korc M, Henne-Bruns D, Kornmann M. 3513 POSTER Interleukin-13 exerts autocrine growth promoting effects in human pancreatic cancer and its expression correlates with a propensity for lymph node metastases European Journal of Cancer Supplements. 5: 263. DOI: 10.1016/s1359-6349(07)71016-9  0.289
2000 Fallon J, Reid S, Kinyamu R, Opole I, Opole R, Baratta J, Korc M, Endo TL, Duong A, Nguyen G, Karkehabadhi M, Twardzik D, Patel S, Loughlin S. In vivo induction of massive proliferation, directed migration, and differentiation of neural cells in the adult mammalian brain. Proceedings of the National Academy of Sciences of the United States of America. 97: 14686-91. PMID 11121069 DOI: 10.1073/Pnas.97.26.14686  0.288
2009 Philip PA, Mooney M, Jaffe D, Eckhardt G, Moore M, Meropol N, Emens L, O'Reilly E, Korc M, Ellis L, Benedetti J, Rothenberg M, Willett C, Tempero M, Lowy A, et al. Consensus report of the national cancer institute clinical trials planning meeting on pancreas cancer treatment. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 27: 5660-9. PMID 19858397 DOI: 10.1200/Jco.2009.21.9022  0.285
1981 Korc M, Iwamoto Y, Sankaran H, Williams JA, Goldfine ID. Insulin action in pancreatic acini from streptozotocin-treated rats. I. Stimulation of protein synthesis American Journal of Physiology-Gastrointestinal and Liver Physiology. 240. PMID 6161541 DOI: 10.1152/Ajpgi.1981.240.1.G56  0.285
2009 Trask HW, Cowper-Sal-lari R, Sartor MA, Gui J, Heath CV, Renuka J, Higgins AJ, Andrews P, Korc M, Moore JH, Tomlinson CR. Microarray analysis of cytoplasmic versus whole cell RNA reveals a considerable number of missed and false positive mRNAs. Rna (New York, N.Y.). 15: 1917-28. PMID 19703940 DOI: 10.1261/Rna.1677409  0.285
1984 Korc M. Manganese Action on Protein Synthesis in Diabetic Rat Pancreas: Evidence for a Possible Physiological Role Journal of Nutrition. 114: 2119-2126. PMID 6491765 DOI: 10.1093/Jn/114.11.2119  0.285
2005 Korc M. Targeted therapeutics in pancreatic cancer: a ray of hope. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 410-1. PMID 15671574  0.284
2016 Kwon JJ, Willy JA, Quirin KA, Wek RC, Korc M, Yin XM, Kota J. Novel role of miR-29a in pancreatic cancer autophagy and its therapeutic potential. Oncotarget. PMID 27626694 DOI: 10.18632/Oncotarget.11928  0.282
2011 Thornley JA, Trask HW, Ridley CJ, Korc M, Gui J, Ringelberg CS, Wang S, Tomlinson CR. Differential regulation of polysome mRNA levels in mouse Hepa-1C1C7 cells exposed to dioxin. Toxicology in Vitro : An International Journal Published in Association With Bibra. 25: 1457-67. PMID 21570461 DOI: 10.1016/J.Tiv.2011.04.020  0.282
1997 Deflorin J, Friess H, Schobinger S, Bründler M, Schilling M, Naef M, Korc M, Büchler MW. Overexpression of the Epidermal Growth Factor Receptor Family in Gastric Cancer Suggests a Role in Tumor Pathogenesis Digestive Surgery. 14: 252-259. DOI: 10.1159/000172554  0.28
1978 Korc M, Sankaran H, Wong KY, Williams JA, Goldfine ID. Insulin receptors in isolated mouse pancreatic acini Biochemical and Biophysical Research Communications. 84: 293-299. PMID 363126 DOI: 10.1016/0006-291X(78)90169-9  0.28
1995 Ebert M, Friess H, Korc M, Büchler M. Altered expression of the human epidermal growth factor (HER) family in acute pancreatitis suggests a prominent role for HER-1 Gastroenterology. 108: A351. DOI: 10.1016/0016-5085(95)24060-8  0.28
1999 Kleeff J, Friess H, Korc M, Büchler M. Gentherapie bei gastrointestinalen Tumoren am Beispiel des Pankreaskarzinoms: Standortbestimmung und Perspektiven Visceral Medicine. 15: 181-187. DOI: 10.1159/000012551  0.28
1998 Ebert M, Kasper HU, Hernberg S, Friess H, Büchler MW, Roessner A, Korc M, Malfertheiner P. Overexpression of platelet-derived growth factor (PDGF) B chain and type beta PDGF receptor in human chronic pancreatitis. Digestive Diseases and Sciences. 43: 567-74. PMID 9539653 DOI: 10.1023/A:1018867209170  0.279
2007 Liu Z, Ishiwata T, Zhou S, Maier S, Henne-Bruns D, Korc M, Bachem M, Kornmann M. Human fibroblast growth factor receptor 1-IIIb is a functional fibroblast growth factor receptor expressed in the pancreas and involved in proliferation and movement of pancreatic ductal cells. Pancreas. 35: 147-57. PMID 17632321 DOI: 10.1097/mpa.0b013e318053e7e3  0.279
1981 Korc M, Owerbach D, Quinto C, Rutter WJ. Pancreatic islet-acinar cell interaction: amylase messenger RNA levels ar determined by insulin. Science (New York, N.Y.). 213: 351-3. PMID 6166044 DOI: 10.1126/Science.6166044  0.279
2017 Andersen DK, Korc M, Petersen GM, Eibl G, Li D, Rickels MR, Chari ST, Abbruzzese JL. Diabetes, Pancreatogenic Diabetes, and Pancreatic Cancer. Diabetes. 66: 1103-1110. PMID 28507210 DOI: 10.2337/Db16-1477  0.278
2007 Carrière C, Seeley ES, Goetze T, Longnecker DS, Korc M. The Nestin progenitor lineage is the compartment of origin for pancreatic intraepithelial neoplasia. Proceedings of the National Academy of Sciences of the United States of America. 104: 4437-42. PMID 17360542 DOI: 10.1073/pnas.0701117104  0.278
1982 Korc M. Regulation of pancreatic protein synthesis by cholecystokinin and calcium American Journal of Physiology-Gastrointestinal and Liver Physiology. 243. PMID 6807107 DOI: 10.1152/Ajpgi.1982.243.1.G69  0.278
1978 Williams JA, Korc M, Dormer RL. Action of secretagogues on a new preparation of functionally intact, isolated pancreatic acini. American Journal of Physiology-Endocrinology and Metabolism. 235: 517-524. PMID 215042 DOI: 10.1152/Ajpendo.1978.235.5.E517  0.278
2014 Slee RB, Grimes BR, Bansal R, Gore J, Blackburn C, Brown L, Gasaway R, Jeong J, Victorino J, March KL, Colombo R, Herbert BS, Korc M. Selective inhibition of pancreatic ductal adenocarcinoma cell growth by the mitotic MPS1 kinase inhibitor NMS-P715. Molecular Cancer Therapeutics. 13: 307-15. PMID 24282275 DOI: 10.1158/1535-7163.Mct-13-0324  0.277
1981 Korc M, Bailey AC, Williams JA. Regulation of protein synthesis in normal and diabetic rat pancreas by cholecystokinin. The American Journal of Physiology. 241: G116-21. PMID 6791509 DOI: 10.1152/Ajpgi.1981.241.2.G116  0.275
1983 Korc M. Manganese action on pancreatic protein synthesis in normal and diabetic rats American Journal of Physiology-Gastrointestinal and Liver Physiology. 245. PMID 6638186 DOI: 10.1152/Ajpgi.1983.245.5.G628  0.275
2007 Fukasawa M, Matsushita A, Korc M. Neuropilin-1 interacts with integrin beta1 and modulates pancreatic cancer cell growth, survival and invasion. Cancer Biology & Therapy. 6: 1173-80. PMID 17726369  0.274
2016 Liu HY, Greene T, Lin TY, Dawes CS, Korc M, Lin CC. Enzyme-mediated stiffening hydrogels for probing activation of pancreatic stellate cells. Acta Biomaterialia. PMID 27769941 DOI: 10.1016/j.actbio.2016.10.027  0.273
1981 Sankaran H, Iwamoto Y, Korc M, Williams JA, Goldfine ID. Insulin action in pancreatic acini from streptozotocin-treated rats. II. Binding of 125I-insulin to receptors. American Journal of Physiology-Gastrointestinal and Liver Physiology. 240. PMID 7006418 DOI: 10.1152/Ajpgi.1981.240.1.G63  0.269
1987 Werner L, Korc M, Brannon PM. Effects of manganese deficiency and dietary composition on rat pancreatic enzyme content. Journal of Nutrition. 117: 2079-2085. PMID 2447251 DOI: 10.1093/Jn/117.12.2079  0.269
2007 Matsushita A, Götze T, Korc M. Hepatocyte growth factor-mediated cell invasion in pancreatic cancer cells is dependent on neuropilin-1. Cancer Research. 67: 10309-16. PMID 17974973 DOI: 10.1158/0008-5472.CAN-07-3256  0.269
1995 Friess H, Büchler M, Hofbauer B, Uhl W, Gold L, Korc M. Overexpression of transforming growth factor βs and their receptors in acute pancreatitis in humans Gastroenterology. 108: A354. DOI: 10.1016/0016-5085(95)24075-6  0.266
2016 Logsdon DP, Grimard M, Luo M, Shahda S, Jiang Y, Tong Y, Yu Z, Zyromski N, Schipani E, Carta F, Supuran CT, Korc M, Ivan M, Kelley MR, Fishel ML. Regulation of HIF1α under Hypoxia by APE1/Ref-1 Impacts CA9 Expression: Dual-Targeting in Patient-Derived 3D Pancreatic Cancer Models. Molecular Cancer Therapeutics. PMID 27535970 DOI: 10.1158/1535-7163.Mct-16-0253  0.266
2017 Kota J, Hancock J, Kwon J, Korc M. Pancreatic Cancer: Stroma and its Current and Emerging Targeted Therapies. Cancer Letters. PMID 28093284 DOI: 10.1016/j.canlet.2016.12.035  0.266
2018 Liu HY, Korc M, Lin CC. Biomimetic and enzyme-responsive dynamic hydrogels for studying cell-matrix interactions in pancreatic ductal adenocarcinoma. Biomaterials. 160: 24-36. PMID 29353105 DOI: 10.1016/j.biomaterials.2018.01.012  0.265
2000 Wildi S, Kleeff JH, Maruyama H, Friess H, Maurer C, Buchler MW, Korc M. Reduction of the angiostatic chemokine SF-1 and concomitant increase of its receptor CXCR-4 in colorectal cancer Gastroenterology. 118: A769. DOI: 10.1016/S0016-5085(00)85215-4  0.264
2011 Carrière C, Mirocha S, Deharvengt S, Gunn JR, Korc M. Aberrant expressions of AP-2α splice variants in pancreatic cancer. Pancreas. 40: 695-700. PMID 21654541 DOI: 10.1097/MPA.0b013e31821f2715  0.264
2012 Cubillos-Ruiz JR, Baird JR, Tesone AJ, Rutkowski MR, Scarlett UK, Camposeco-Jacobs AL, Anadon-Arnillas J, Harwood NM, Korc M, Fiering SN, Sempere LF, Conejo-Garcia JR. Reprogramming tumor-associated dendritic cells in vivo using miRNA mimetics triggers protective immunity against ovarian cancer. Cancer Research. 72: 1683-93. PMID 22307839 DOI: 10.1158/0008-5472.Can-11-3160  0.263
2000 Kornmann M, Ishiwata T, Lopez ME, Beger HG, Korc M. The IIIc splice variant of FGF receptor-1 contributesto the transformation of pancreatic ductal cells in vitro and in vivo Gastroenterology. 118: A1056. DOI: 10.1016/S0016-5085(00)86375-1  0.263
2010 Preis M, Korc M. Kinase signaling pathways as targets for intervention in pancreatic cancer. Cancer Biology & Therapy. 9: 754-63. PMID 20234186  0.263
2014 Korc M. p38 MAPK in pancreatic cancer: finding a protective needle in the haystack. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 5866-8. PMID 25135483 DOI: 10.1158/1078-0432.CCR-14-1543  0.262
2002 di Mola FF, Friess H, Riesle E, Koliopanos A, Büchler P, Zhu Z, Brigstock DR, Korc M, Büchler MW. Connective tissue growth factor is involved in pancreatic repair and tissue remodeling in human and rat acute necrotizing pancreatitis. Annals of Surgery. 235: 60-7. PMID 11753043 DOI: 10.1097/00000658-200201000-00008  0.262
2012 Ali S, Banerjee S, Logna F, Bao B, Philip PA, Korc M, Sarkar FH. Inactivation of Ink4a/Arf leads to deregulated expression of miRNAs in K-Ras transgenic mouse model of pancreatic cancer. Journal of Cellular Physiology. 227: 3373-80. PMID 22213426 DOI: 10.1002/Jcp.24036  0.262
1995 Ebert M, Yokoyama M, Friess H, Büchler M, Korc M. Overexpression of platelet-derived growth factor (PDGF) receptors in human pancreatic ductal adenocarcinoma Gastroenterology. 108: A351. DOI: 10.1016/0016-5085(95)24062-4  0.26
2004 Korc M. Update on diabetes mellitus. Disease Markers. 20: 161-5. PMID 15502249 DOI: 10.1155/2004/945073  0.259
1987 Bell C, Rosenblum M, Harsh G, Korc M, Meltzer P, Trent J. 12 Correlation of chromosome 7 alterations with expression of epidermal growth factor receptor (EGF) in human glial and pancreatic carcinomas Cancer Genetics and Cytogenetics. 28: 31. DOI: 10.1016/0165-4608(87)90291-3  0.259
2018 Enane FO, Saunthararajah Y, Korc M. Differentiation therapy and the mechanisms that terminate cancer cell proliferation without harming normal cells. Cell Death & Disease. 9: 912. PMID 30190481 DOI: 10.1038/s41419-018-0919-9  0.258
2006 Ishiwata T, Kudo M, Onda M, Fujii T, Teduka K, Suzuki T, Korc M, Naito Z. Defined localization of nestin-expressing cells in L-arginine-induced acute pancreatitis. Pancreas. 32: 360-8. PMID 16670618 DOI: 10.1097/01.mpa.0000220860.01120.21  0.257
1999 Lee WL, Chen JW, Ting CT, Ishiwata T, Lin SJ, Korc M, Wang PH. Insulin-Like Growth Factor I Improves Cardiovascular Function and Suppresses Apoptosis of Cardiomyocytes in Dilated Cardiomyopathy1. Endocrinology. 140: 4831-4840. PMID 28200652 DOI: 10.1210/Endo.140.10.7082  0.256
2018 Quirin KA, Kwon JJ, Alioufi A, Factora T, Temm CJ, Jacobsen M, Sandusky GE, Shontz K, Chicoine LG, Clark KR, Mendell JT, Korc M, Kota J. Safety and Efficacy of AAV Retrograde Pancreatic Ductal Gene Delivery in Normal and Pancreatic Cancer Mice. Molecular Therapy. Methods & Clinical Development. 8: 8-20. PMID 29349096 DOI: 10.1016/j.omtm.2017.09.006  0.253
2021 Principe DR, Korc M, Kamath SD, Munshi HG, Rana A. Trials and tribulations of pancreatic cancer immunotherapy. Cancer Letters. PMID 33549709 DOI: 10.1016/j.canlet.2021.01.031  0.251
2014 Gore AJ, Deitz SL, Palam LR, Craven KE, Korc M. Pancreatic cancer-associated retinoblastoma 1 dysfunction enables TGF-β to promote proliferation. The Journal of Clinical Investigation. 124: 338-52. PMID 24334458 DOI: 10.1172/Jci71526  0.251
1983 Korc M. Effect of lanthanum on pancreatic protein synthesis in streptozotocin-diabetic rats American Journal of Physiology-Gastrointestinal and Liver Physiology. 244. PMID 6299118 DOI: 10.1152/Ajpgi.1983.244.3.G321  0.249
2012 Liu F, Korc M. Cdk4/6 inhibition induces epithelial-mesenchymal transition and enhances invasiveness in pancreatic cancer cells. Molecular Cancer Therapeutics. 11: 2138-48. PMID 22869556 DOI: 10.1158/1535-7163.MCT-12-0562  0.246
1998 Friess H, Lu Z, Graber H, Zimmermann A, Andren-Sandberg A, Adler G, Korc M, Schmid R, Büchler M. Disturbance in apoptosis influences the outcome of patients with pancreatic cancer Gastroenterology. 114: A597. DOI: 10.1016/S0016-5085(98)82435-9  0.245
1999 di Mola FF, Friess H, Martignoni ME, Di Sebastiano P, Zimmermann A, Innocenti P, Graber H, Gold LI, Korc M, Büchler MW. Connective tissue growth factor is a regulator for fibrosis in human chronic pancreatitis. Annals of Surgery. 230: 63-71. PMID 10400038 DOI: 10.1097/00000658-199907000-00010  0.245
2015 Shannon HE, Fishel ML, Xie J, Gu D, McCarthy BP, Riley AA, Sinn AL, Silver JM, Peterman K, Kelley MR, Hanenberg H, Korc M, Pollok KE, Territo PR. Longitudinal Bioluminescence Imaging of Primary Versus Abdominal Metastatic Tumor Growth in Orthotopic Pancreatic Tumor Models in NSG Mice. Pancreas. 44: 64-75. PMID 25406955 DOI: 10.1097/Mpa.0000000000000238  0.239
1994 Friess H, Korc M, Büchler MW. Growth Factors and Growth Factor Receptors in Benign Pancreatic Disorders Digestive Surgery. 11: 138-142. DOI: 10.1159/000172243  0.238
2012 Morden NE, Liu SK, Smith J, Mackenzie TA, Skinner J, Korc M. Response to Comment on: Morden et al. Further Exploration of the Relationship Between Insulin Glargine and Incident Cancer: A Retrospective Cohort Study of Older Medicare Patients. Diabetes Care 2011;34:1965-1971 Diabetes Care. 35: e16-e16. DOI: 10.2337/Dc11-2080  0.236
2007 Wildi S, Kleeff J, Mayerle J, Zimmermann A, Böttinger EP, Wakefield L, Büchler MW, Friess H, Korc M. Suppression of transforming growth factor beta signalling aborts caerulein induced pancreatitis and eliminates restricted stimulation at high caerulein concentrations. Gut. 56: 685-92. PMID 17135311 DOI: 10.1136/Gut.2006.105833  0.235
1987 Korc M, Schoni MH. Modulation of cytosolic free calcium levels by extracellular phosphate and lanthanum. Proceedings of the National Academy of Sciences of the United States of America. 84: 1282-1285. PMID 3469669 DOI: 10.1073/Pnas.84.5.1282  0.234
1998 Kornmann M, Ishiwata T, Arber N, Beger HG, Korc M. Increased cyclin D1 expression in chronic pancreatitis. Pancreas. 17: 158-62. PMID 9700947 DOI: 10.1097/00006676-199808000-00008  0.233
2016 Korc M. Sugar-Coated Proteins Pave the Way to Improving Pancreatic Cancer Diagnosis. Cellular and Molecular Gastroenterology and Hepatology. 2: 118-119. PMID 28174710 DOI: 10.1016/j.jcmgh.2016.01.001  0.231
2012 Kerley-Hamilton JS, Trask HW, Ridley CJ, Dufour E, Ringelberg CS, Nurinova N, Wong D, Moodie KL, Shipman SL, Moore JH, Korc M, Shworak NW, Tomlinson CR. Obesity is mediated by differential aryl hydrocarbon receptor signaling in mice fed a Western diet. Environmental Health Perspectives. 120: 1252-9. PMID 22609946 DOI: 10.1289/Ehp.1205003  0.23
1988 Korc M, Schöni MH. Quin 2 and Manganese Define Multiple Alterations in Cellular Calcium Homeostasis in Diabetic Rat Pancreas Diabetes. 37: 13-20. PMID 3121414 DOI: 10.2337/Diab.37.1.13  0.229
2014 Joshi GK, Deitz-McElyea S, Johnson M, Mali S, Korc M, Sardar R. Highly specific plasmonic biosensors for ultrasensitive microRNA detection in plasma from pancreatic cancer patients. Nano Letters. 14: 6955-63. PMID 25379951 DOI: 10.1021/Nl503220S  0.228
2014 Cote GA, Gore AJ, McElyea SD, Heathers LE, Xu H, Sherman S, Korc M. A pilot study to develop a diagnostic test for pancreatic ductal adenocarcinoma based on differential expression of select miRNA in plasma and bile. The American Journal of Gastroenterology. 109: 1942-52. PMID 25350767 DOI: 10.1038/Ajg.2014.331  0.228
1989 Siwik SA, Korc M. Manganese attenuates secretagogue-mediated phospholipid hydrolysis in AR42J cells Life Sciences. 45: 1959-1965. PMID 2557509 DOI: 10.1016/0024-3205(89)90570-5  0.227
1997 Riesle E, Friess H, Zhao L, Wagner M, Uhl W, Baczako K, Gold LI, Korc M, Büchler MW. Increased expression of transforming growth factor beta s after acute oedematous pancreatitis in rats suggests a role in pancreatic repair. Gut. 40: 73-9. PMID 9155579 DOI: 10.1136/gut.40.1.73  0.227
2018 Baracos VE, Martin L, Korc M, Guttridge DC, Fearon KCH. Cancer-associated cachexia. Nature Reviews. Disease Primers. 4: 17105. PMID 29345251 DOI: 10.1038/nrdp.2017.105  0.225
2019 Korc M. Pathogenesis of Pancreatic Cancer-Related Diabetes Mellitus: Quo Vadis? Pancreas. 48: 594-597. PMID 31090659 DOI: 10.1097/MPA.0000000000001300  0.22
2003 Korc M. Diabetes mellitus in the era of proteomics. Molecular & Cellular Proteomics : McP. 2: 399-404. PMID 12851465 DOI: 10.1074/Mcp.R300005-Mcp200  0.22
1988 Sugg EE, Serra M, Shook JE, Yamamura HI, Burks TF, Korc M, Hruby VJ. Cholecystokinic activity of N alpha-hydroxysulfonyl-[Nle28,31]CCK26-33 analogues modified at the C-terminal residue. International Journal of Peptide and Protein Research. 31: 514-9. PMID 2457563 DOI: 10.1111/J.1399-3011.1988.Tb00910.X  0.219
2013 Andersen DK, Andren-Sandberg Å, Duell EJ, Goggins M, Korc M, Petersen GM, Smith JP, Whitcomb DC. Pancreatitis-diabetes-pancreatic cancer: summary of an NIDDK-NCI workshop. Pancreas. 42: 1227-37. PMID 24152948 DOI: 10.1097/MPA.0b013e3182a9ad9d  0.215
1991 Glinsmann-Gibson BJ, Korc M. Regulation of transforming growth factor-alpha mRNA expression in T3M4 human pancreatic carcinoma cells. Pancreas. 6: 142-9. PMID 1886882 DOI: 10.1097/00006676-199103000-00003  0.214
2018 Gbolahan OB, Sehdev A, Shahda S, Perkins S, Korc M, Loehrer PJ, O'Neil BH. A phase II trial of cabozantinib and erlotinib for patients with EGFR and c-MET co-expressing metastatic pancreatic adenocarcinoma. Journal of Clinical Oncology. 36: TPS4157-TPS4157. DOI: 10.1200/Jco.2018.36.15_Suppl.Tps4157  0.211
2017 Korc M, Jeon CY, Edderkaoui M, Pandol SJ, Petrov MS. Tobacco and alcohol as risk factors for pancreatic cancer. Best Practice & Research. Clinical Gastroenterology. 31: 529-536. PMID 29195672 DOI: 10.1016/j.bpg.2017.09.001  0.209
2014 Prabhu L, Mundade R, Korc M, Loehrer PJ, Lu T. Critical role of NF-κB in pancreatic cancer. Oncotarget. 5: 10969-75. PMID 25473891  0.207
2018 Hart PA, Andersen DK, Mather KJ, Castonguay AC, Bajaj M, Bellin MD, Bradley D, Contreras N, Habtezion A, Korc M, Kudva Y, Petrov MS, Whitcomb DC, Yadav D, Yuan Y, et al. Evaluation of a Mixed Meal Test for Diagnosis and Characterization of PancrEaTogEniC DiabeTes Secondary to Pancreatic Cancer and Chronic Pancreatitis: Rationale and Methodology for the DETECT Study From the Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer. Pancreas. 47: 1239-1243. PMID 30325863 DOI: 10.1097/Mpa.0000000000001168  0.204
1999 Friess H, Zhu ZW, di Mola FF, Kulli C, Graber HU, Andren-Sandberg A, Zimmermann A, Korc M, Reinshagen M, Büchler MW. Nerve growth factor and its high-affinity receptor in chronic pancreatitis. Annals of Surgery. 230: 615-24. PMID 10561084 DOI: 10.1097/00000658-199911000-00002  0.204
2013 Kramer-Marek G, Gore J, Korc M. Molecular imaging in pancreatic cancer--a roadmap for therapeutic decisions. Cancer Letters. 341: 132-8. PMID 23941833 DOI: 10.1016/j.canlet.2013.08.008  0.196
2017 Duell EJ, Lujan-Barroso L, Sala N, Deitz McElyea S, Overvad K, Tjonneland A, Olsen A, Weiderpass E, Busund LT, Moi L, Muller D, Vineis P, Aune D, Matullo G, Naccarati A, ... ... Korc M, et al. Plasma microRNAs as biomarkers of pancreatic cancer risk in a prospective cohort study. International Journal of Cancer. PMID 28542740 DOI: 10.1002/ijc.30790  0.195
2022 Principe DR, Kamath SD, Korc M, Munshi HG. The immune modifying effects of chemotherapy and advances in chemo-immunotherapy. Pharmacology & Therapeutics. 236: 108111. PMID 35016920 DOI: 10.1016/j.pharmthera.2022.108111  0.192
2003 Ebert MP, Yu J, Hoffmann J, Rocco A, Röcken C, Kahmann S, Müller O, Korc M, Sung JJ, Malfertheiner P. Loss of beta-catenin expression in metastatic gastric cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 21: 1708-14. PMID 12721245 DOI: 10.1200/Jco.2003.10.017  0.192
1991 Sundareshan P, Misiorowski RL, Davis JR, Korc M, Hendrix MJ. Effects of epidermal growth factor on growth response, morphology, and invasive potential of human endometrial carcinoma cell line RL95-2. Cancer Communications. 3: 149-58. PMID 1904255 DOI: 10.3727/095535491820873380  0.191
1986 Sugg EE, Shook JE, Serra M, Korc M, Yamamura HI, Burks TF, Hruby VJ. Synthesis and biological evaluation of N alpha-hydroxysulfonyl-[Nle28,31]-CCK26-33. Life Sciences. 39: 1623-9. PMID 2430160 DOI: 10.1016/0024-3205(86)90158-X  0.191
1995 Friess H, Deflorin J, Furlan N, Schilling M, Korc M, Büchler M. Epidermal growth factor receptor but not C-ERBB-3 is overexpressed in oesophageal carcinomas Gastroenterology. 108: A470. DOI: 10.1016/0016-5085(95)26196-6  0.189
2018 Yip-Schneider MT, Simpson R, Carr RA, Wu H, Fan H, Liu Z, Korc M, Zhang J, Schmidt CM. Circulating Leptin and Branched Chain Amino Acids-Correlation with Intraductal Papillary Mucinous Neoplasm Dysplastic Grade. Journal of Gastrointestinal Surgery : Official Journal of the Society For Surgery of the Alimentary Tract. PMID 30215202 DOI: 10.1007/s11605-018-3963-y  0.185
2010 Whipple CA, Korc M. Angiogenesis signaling pathways as targets in cancer therapy Handbook of Cell Signaling, 2/E. 3: 2895-2905. DOI: 10.1016/B978-0-12-374145-5.00333-8  0.184
1997 Friess H, Cantero D, Graber H, Tang WH, Guo X, Kashiwagi M, Zimmermann A, Gold L, Korc M, Büchler MW. Enhanced urokinase plasminogen activation in chronic pancreatitis suggests a role in its pathogenesis. Gastroenterology. 113: 904-13. PMID 9287983 DOI: 10.1016/S0016-5085(97)70186-0  0.183
2011 Morden NE, Liu SK, Smith J, Mackenzie TA, Skinner J, Korc M. Further exploration of the relationship between insulin glargine and incident cancer: a retrospective cohort study of older Medicare patients. Diabetes Care. 34: 1965-71. PMID 21775752 DOI: 10.2337/dc11-0699  0.182
2006 Korc M. The joy of discovery. Cancer Biology & Therapy. 5: 884-8. PMID 16880731 DOI: 10.4161/Cbt.5.7.3121  0.18
1993 Yamanaka Y, Friess H, Büchler M, Beger HG, Gold LI, Korc M. Synthesis and expression of transforming growth factor beta-1, beta-2, and beta-3 in the endocrine and exocrine pancreas. Diabetes. 42: 746-56. PMID 8482432 DOI: 10.2337/diab.42.5.746  0.174
1991 Korc M, Chandrasekar B, Siwik SA. Cholecystokinin-induced phosphatidylinositol hydrolysis in rat pancreatic acinar cells: modulation by extracellular calcium and manganese. Endocrinology. 129: 39-46. PMID 1647303 DOI: 10.1210/endo-129-1-39  0.173
2016 Nguyen HV, Gore J, Zhong X, Savant SS, Deitz-McElyea S, Schmidt CM, House MG, Korc M. MicroRNA Expression in a Readily Accessible Common Hepatic Artery Lymph Node Predicts Time to Pancreatic Cancer Recurrence Postresection. Journal of Gastrointestinal Surgery : Official Journal of the Society For Surgery of the Alimentary Tract. PMID 27456015 DOI: 10.1007/s11605-016-3208-x  0.172
2021 Principe DR, Underwood PW, Korc M, Trevino JG, Munshi HG, Rana A. The Current Treatment Paradigm for Pancreatic Ductal Adenocarcinoma and Barriers to Therapeutic Efficacy. Frontiers in Oncology. 11: 688377. PMID 34336673 DOI: 10.3389/fonc.2021.688377  0.168
2017 Eibl G, Cruz-Monserrate Z, Korc M, Petrov MS, Goodarzi MO, Fisher WE, Habtezion A, Lugea A, Pandol SJ, Hart PA, Andersen DK. Diabetes Mellitus and Obesity as Risk Factors for Pancreatic Cancer. Journal of the Academy of Nutrition and Dietetics. PMID 28919082 DOI: 10.1016/J.Jand.2017.07.005  0.165
1999 Baer HU, Friess H, Abou-Shady M, Berberat P, Zimmermann A, Gold LI, Korc M, Büchler MW. Transforming growth factor betas and their receptors in human liver cirrhosis. European Journal of Gastroenterology & Hepatology. 10: 1031-9. PMID 9895050 DOI: 10.1097/00042737-199812000-00009  0.16
1999 Doeberitz MvK, Doeberitz CvK, Friess H, Kleeff J, Klockow N, Zöller M, Matzku S, Weitz J, Koch M, Schmid RM, Gansauge F, Werner M, Höfler H, Moehler M, Heike M, ... ... Korc M, et al. Band 15, Heft 2, Juni 1999 Visceral Medicine. 15: 105-108. DOI: 10.1159/000012556  0.158
2015 Nguyen HV, Korc M, Gore J, Zhong X, Savant S, Schmidt CM. MicroRNA expression in common hepatic artery lymph nodes as a prognostic marker in pancreatic ductal adenocarcinoma Journal of the American College of Surgeons. 221: e131. DOI: 10.1016/j.jamcollsurg.2015.08.250  0.158
1998 Kleeff J, Korc M. Transcriptional up-regulation of transforming growth factor-β (TGF-β) receptors by TGF-β1 correlates with expression of cyclin d-dependent kinase inhibitors Gastroenterology. 114: A626. DOI: 10.1016/S0016-5085(98)82557-2  0.157
2018 Simpson RE, Yip-Schneider MT, Wu H, Fan H, Liu Z, Korc M, Zhang J, Schmidt CM. Circulating Thrombospondin-2 enhances prediction of malignant intraductal papillary mucinous neoplasm. American Journal of Surgery. PMID 30293901 DOI: 10.1016/j.amjsurg.2018.08.026  0.153
1993 Yamanaka Y, Friess H, Buchler M, Beger HG, Gold LI, Korc M. Synthesis and expression of transforming growth factor beta-1, beta-2, and beta-3 in the endocrine and exocrine pancreas Diabetes. 42: 746-756. DOI: 10.2337/diabetes.42.5.746  0.151
2018 Abbruzzese JL, Andersen DK, Borrebaeck CAK, Chari ST, Costello E, Cruz-Monserrate Z, Eibl G, Engleman EG, Fisher WE, Habtezion A, Kim SK, Korc M, Logsdon C, Lyssiotis CA, Pandol SJ, et al. The Interface of Pancreatic Cancer With Diabetes, Obesity, and Inflammation: Research Gaps and Opportunities: Summary of a National Institute of Diabetes and Digestive and Kidney Diseases Workshop. Pancreas. 47: 516-525. PMID 29702529 DOI: 10.1097/Mpa.0000000000001037  0.147
2013 Gore A, Norris A, Korc M. RB loss in conjunction with oncogenic Kras causes perturbations in TGF-β signaling and upregulates AGR2 expression Pancreatology. 13: e27-e28. DOI: 10.1016/j.pan.2012.12.149  0.144
2015 Craven KE, Gore J, Korc M. Overview of pre-clinical and clinical studies targeting angiogenesis in pancreatic ductal adenocarcinoma. Cancer Letters. PMID 26723874 DOI: 10.1016/j.canlet.2015.11.047  0.143
2015 Craven KE, Gore J, Korc M. Overview of pre-clinical and clinical studies targeting angiogenesis in pancreatic ductal adenocarcinoma Cancer Letters. DOI: 10.1016/j.canlet.2015.11.047  0.142
1996 Horvath LZ, Friess H, Schilling M, Borisch B, Deflorin J, Gold LI, Korc M, Büchler MW. Altered expression of transforming growth factor-beta S in chronic renal rejection. Kidney International. 50: 489-98. PMID 8840277 DOI: 10.1038/ki.1996.340  0.14
2016 Hart PA, Bellin MD, Andersen DK, Bradley D, Cruz-Monserrate Z, Forsmark CE, Goodarzi MO, Habtezion A, Korc M, Kudva YC, Pandol SJ, Yadav D, Chari ST. Type 3c (pancreatogenic) diabetes mellitus secondary to chronic pancreatitis and pancreatic cancer. The Lancet. Gastroenterology & Hepatology. 1: 226-237. PMID 28404095 DOI: 10.1016/S2468-1253(16)30106-6  0.138
2005 Samnotra V, Memoli VA, Ernstoff MS, Tretter CPG, Heaney JA, Korc M, Farell TJ, Simmons P. Primary adrenocortical tumors: EGFR, c-Kit and Her-2/neu receptor staining patterns Journal of Clinical Oncology. 23: 4770-4770. DOI: 10.1200/JCO.2005.23.16_SUPPL.4770  0.137
2017 Coté GA, Xu H, Easler JJ, Imler TD, Teal E, Sherman S, Korc M. Informative patterns of health care utilization prior to the diagnosis of pancreatic ductal adenocarcinoma. American Journal of Epidemiology. PMID 28541521 DOI: 10.1093/Aje/Kwx168  0.135
2001 Zhu ZW, Friess H, Wang L, Abou-Shady M, Zimmermann A, Lander AD, Korc M, Kleeff J, Büchler MW. Enhanced glypican-3 expression differentiates the majority of hepatocellular carcinomas from benign hepatic disorders. Gut. 48: 558-64. PMID 11247902 DOI: 10.1136/gut.48.4.558  0.135
2022 Hart PA, Papachristou GI, Park WG, Dyer AM, Chinchilli VM, Afghani E, Akshintala VS, Andersen DK, Buxbaum JL, Conwell DL, Dungan KM, Easler JJ, Fogel EL, Greenbaum CJ, Kalyani RR, ... Korc M, et al. Rationale and Design for the Diabetes RElated to Acute Pancreatitis and Its Mechanisms Study: A Prospective Cohort Study From the Type 1 Diabetes in Acute Pancreatitis Consortium. Pancreas. 51: 568-574. PMID 36206460 DOI: 10.1097/MPA.0000000000002079  0.134
2012 Pipas JM, Zaki BI, McGowan MM, Tsapakos MJ, Ripple GH, Suriawinata AA, Tsongalis GJ, Colacchio TA, Gordon SR, Sutton JE, Srivastava A, Smith KD, Gardner TB, Korc M, Davis TH, et al. Neoadjuvant cetuximab, twice-weekly gemcitabine, and intensity-modulated radiotherapy (IMRT) in patients with pancreatic adenocarcinoma. Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo. 23: 2820-7. PMID 22571859 DOI: 10.1093/annonc/mds109  0.13
2017 Pendharkar SA, Drury M, Walia M, Korc M, Petrov MS. Gastrin-Releasing Peptide and Glucose Metabolism Following Pancreatitis. Gastroenterology Research. 10: 224-234. PMID 28912908 DOI: 10.14740/gr890w  0.121
2017 Vasudevaraja V, Renbarger J, Shah RG, Kinnebrew G, Korc M, Wang L, Huo Y, Liu E, Li L, Cheng L. PMTDS: a computational method based on genetic interaction networks for Precision Medicine Target-Drug Selection in cancer Quantitative Biology. 5: 380-394. DOI: 10.1007/s40484-017-0126-1  0.118
2016 Shih H, Greene T, Korc M, Lin CC. Modular and Adaptable Tumor Niche Prepared from Visible Light Initiated Thiol-Norbornene Photopolymerization. Biomacromolecules. 17: 3872-3882. PMID 27936722 DOI: 10.1021/acs.biomac.6b00931  0.117
2012 Al-Haddad MA, Schmidt CM, Korc M, Li L, Skaar T. Mo1195 miRNA Can Identify Intraductal Papillary Mucinous Neoplasms (IPMNs) With Advanced Dysplasia Gastroenterology. 142: S-618-S-619. DOI: 10.1016/S0016-5085(12)62375-0  0.111
2015 Han B, Qu C, Park K, Korc M, Konieczny SF. Recapitulation of complex transport and action of drugs at tumor microenvironment using tumor-microenvironment-on-chip. Cancer Letters. PMID 26688098 DOI: 10.1016/J.Canlet.2015.12.003  0.105
1995 Friess H, Berberat P, Deflorin J, Baer H, Gold L, Korc M, Büchler M. Overexpression of TGF-β1 and TGF-β receptor type II but not of TGF-β2 and TGF-β receptor type III in human liver cirrhosis Gastroenterology. 108: A1067. DOI: 10.1016/0016-5085(95)28570-9  0.103
2008 Patnaik A, Pipas M, Rosen LS, Wood L, Phipps K, Mulay M, Garay C, Korc M, Sarantopoulos J. A phase I dose escalation and pharmacokinetic (PK) study of intravenous (iv) aflibercept (VEGF Trap) plus weekly gemcitabine (Gem) in patients (pts) with advanced solid tumors: preliminary results. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 26: 3558. PMID 27949663 DOI: 10.1200/jco.2008.26.15_suppl.3558  0.091
2014 Sina M, Coté GA, Korc M. Improving the diagnostic accuracy of endoscopic ultrasound-guided fine-needle aspiration using microRNAs. Gastroenterology. 147: 930-2. PMID 25150790 DOI: 10.1053/j.gastro.2014.08.015  0.083
1998 di Mola F, Friess H, Scheuren A, Di Sebastiano P, Graber H, Egger B, Zimmermann A, Korc M, Büchler M. TGF-βs and their receptors influence the outcome in Crohn's disease Gastroenterology. 114: A966. DOI: 10.1016/S0016-5085(98)83933-4  0.081
2000 Kleeff JH, Zhu Z, Wang L, Zimmermann A, Korc M, Friess H, Buchler MW. Glypican-3 is a potential tumor marker for hepatocellular carcinoma Gastroenterology. 118: A261. DOI: 10.1016/S0016-5085(00)83121-2  0.074
1998 Friess H, Guo X, DiMola F, Heinicke J, Andren-Sandberg A, Graber H, Baer H, Zimmermann A, Korc M, Büchler M. KaI1 influences the metastatic potential in hepatocellular carcinomas Gastroenterology. 114: A1242-A1243. DOI: 10.1016/S0016-5085(98)85041-5  0.039
1998 Wang PH, Korc M. Searching for the Holy Grail: the cause of diabetes. Lancet (London, England). s4. PMID 9454047 DOI: 10.1016/0140-6736(95)90003-9  0.019
2015 Cote GA, Gore AJ, McElyea SD, Xu H, Sherman S, Korc M. Response to Le Large et al. The American Journal of Gastroenterology. 110: 769-70. PMID 25942303 DOI: 10.1038/Ajg.2015.82  0.01
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