Lucas B. Sullivan, Ph.D. - Publications

Affiliations: 
2013 Integrated Graduate Program in the Life Sciences Northwestern University, Evanston, IL 
Area:
Cell Biology, Biochemistry, Medicine and Surgery

26 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Rossmann MP, Hoi K, Chan V, Abraham BJ, Yang S, Mullahoo J, Papanastasiou M, Wang Y, Elia I, Perlin JR, Hagedorn EJ, Hetzel S, Weigert R, Vyas S, Nag PP, Sullivan LB, et al. Cell-specific transcriptional control of mitochondrial metabolism by TIF1γ drives erythropoiesis. Science (New York, N.Y.). 372: 716-721. PMID 33986176 DOI: 10.1126/science.aaz2740  0.01
2020 Davidsen K, Sullivan LB. Free Asparagine or Die: Cancer Cells Require Proteasomal Protein Breakdown to Survive Asparagine Depletion. Cancer Discovery. 10: 1632-1634. PMID 33139341 DOI: 10.1158/2159-8290.CD-20-1251  0.01
2020 Li Y, Ivica NA, Dong T, Papageorgiou DP, He Y, Brown DR, Kleyman M, Hu G, Chen WW, Sullivan LB, Del Rosario A, Hammond PT, Vander Heiden MG, Chen J. MFSD7C switches mitochondrial ATP synthesis to thermogenesis in response to heme. Nature Communications. 11: 4837. PMID 32973183 DOI: 10.1038/s41467-020-18607-1  0.01
2020 Augert A, Mathsyaraja H, Ibrahim AH, Freie B, Geuenich MJ, Cheng PF, Alibeckoff SP, Wu N, Hiatt JB, Basom R, Gazdar A, Sullivan LB, Eisenman RN, MacPherson D. MAX Functions as a Tumor Suppressor and Rewires Metabolism in Small Cell Lung Cancer. Cancer Cell. PMID 32470392 DOI: 10.1016/J.Ccell.2020.04.016  0.01
2020 Quon E, Hart ML, Sullivan LB. Redox Debt Leads to Metabolic Bankruptcy in Tumors. Trends in Cancer. 6: 359-361. PMID 32348730 DOI: 10.1016/J.Trecan.2020.02.012  0.01
2018 Sullivan LB. Metabolic Frugality Marks Cancer Cells for Immune Targeting. Cell. 174: 1344-1346. PMID 30193108 DOI: 10.1016/J.Cell.2018.08.023  0.01
2018 Sullivan LB, Luengo A, Danai LV, Bush LN, Diehl FF, Hosios AM, Lau AN, Elmiligy S, Malstrom S, Lewis CA, Vander Heiden MG. Aspartate is an endogenous metabolic limitation for tumour growth. Nature Cell Biology. PMID 29941931 DOI: 10.1038/S41556-018-0125-0  0.01
2017 Sullivan LB. Extracellular vesicles: Taking metabolism on the road. Nature Chemical Biology. 13: 924-925. PMID 28820875 DOI: 10.1038/Nchembio.2455  0.01
2016 Gui DY, Sullivan LB, Luengo A, Hosios AM, Bush LN, Gitego N, Davidson SM, Freinkman E, Thomas CJ, Vander Heiden MG. Environment Dictates Dependence on Mitochondrial Complex I for NAD+ and Aspartate Production and Determines Cancer Cell Sensitivity to Metformin. Cell Metabolism. PMID 27746050 DOI: 10.1016/J.Cmet.2016.09.006  0.01
2016 Sullivan LB, Gui DY, Heiden MG. Altered metabolite levels in cancer: implications for tumour biology and cancer therapy. Nature Reviews. Cancer. PMID 27658530 DOI: 10.1038/Nrc.2016.85  0.6
2016 Pacold ME, Brimacombe KR, Chan SH, Rohde JM, Lewis CA, Swier LJ, Possemato R, Chen WW, Sullivan LB, Fiske BP, Cho S, Freinkman E, Birsoy K, Abu MR, Shaul YD, et al. Corrigendum: A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate. Nature Chemical Biology. 12: 656. PMID 27434767 DOI: 10.1038/Nchembio0816-656  0.01
2016 Pacold ME, Brimacombe KR, Chan SH, Rohde JM, Lewis CA, Swier LJ, Possemato R, Chen WW, Sullivan LB, Fiske BP, Cho S, Freinkman E, Birsoy K, Abu-Remaileh M, Shaul YD, et al. A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate. Nature Chemical Biology. PMID 27110680 DOI: 10.1038/Nchembio.2070  0.6
2016 Olenchock BA, Moslehi J, Baik AH, Davidson SM, Williams J, Gibson WJ, Chakraborty AA, Pierce KA, Miller CM, Hanse EA, Kelekar A, Sullivan LB, Wagers AJ, Clish CB, Vander Heiden MG, et al. EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection. Cell. 165: 497. PMID 27058668 DOI: 10.1016/J.Cell.2016.03.037  0.01
2016 Olenchock BA, Moslehi J, Baik AH, Davidson SM, Williams J, Gibson WJ, Pierce KA, Miller CM, Hanse EA, Kelekar A, Sullivan LB, Wagers AJ, Clish CB, Vander Heiden MG, Kaelin WG. EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection. Cell. 164: 884-895. PMID 26919427 DOI: 10.1016/J.Cell.2016.02.006  0.6
2016 Hecht VC, Sullivan LB, Kimmerling RJ, Kim DH, Hosios AM, Stockslager MA, Stevens MM, Kang JH, Wirtz D, Vander Heiden MG, Manalis SR. Biophysical changes reduce energetic demand in growth factor-deprived lymphocytes. The Journal of Cell Biology. 212: 439-47. PMID 26880201 DOI: 10.1083/Jcb.201506118  0.6
2016 Davidson SM, Papagiannakopoulos T, Olenchock BA, Heyman JE, Keibler MA, Luengo A, Bauer MR, Jha AK, O'Brien JP, Pierce KA, Gui DY, Sullivan LB, Wasylenko TM, Subbaraj L, Chin CR, et al. Environment Impacts the Metabolic Dependencies of Ras-Driven Non-Small Cell Lung Cancer. Cell Metabolism. PMID 26853747 DOI: 10.1016/J.Cmet.2016.01.007  0.6
2015 Sullivan LB, Gui DY, Hosios AM, Bush LN, Freinkman E, Vander Heiden MG. Supporting Aspartate Biosynthesis Is an Essential Function of Respiration in Proliferating Cells. Cell. 162: 552-63. PMID 26232225 DOI: 10.1016/J.Cell.2015.07.017  0.6
2014 Sullivan LB, Chandel NS. Mitochondrial reactive oxygen species and cancer. Cancer & Metabolism. 2: 17. PMID 25671107 DOI: 10.1186/2049-3002-2-17  0.44
2014 Luengo A, Sullivan LB, Heiden MG. Understanding the complex-I-ty of metformin action: limiting mitochondrial respiration to improve cancer therapy. Bmc Biology. 12: 82. PMID 25347702 DOI: 10.1186/S12915-014-0082-4  0.6
2014 Mullen AR, Hu Z, Shi X, Jiang L, Boroughs LK, Kovacs Z, Boriack R, Rakheja D, Sullivan LB, Linehan WM, Chandel NS, DeBerardinis RJ. Oxidation of alpha-ketoglutarate is required for reductive carboxylation in cancer cells with mitochondrial defects. Cell Reports. 7: 1679-90. PMID 24857658 DOI: 10.1016/J.Celrep.2014.04.037  0.44
2014 Wheaton WW, Weinberg SE, Hamanaka RB, Soberanes S, Sullivan LB, Anso E, Glasauer A, Dufour E, Mutlu GM, Budigner GS, Chandel NS. Metformin inhibits mitochondrial complex I of cancer cells to reduce tumorigenesis. Elife. 3: e02242. PMID 24843020 DOI: 10.7554/Elife.02242  0.6
2014 Sullivan LB, Chandel NS. Mitochondrial metabolism in TCA cycle mutant cancer cells. Cell Cycle (Georgetown, Tex.). 13: 347-8. PMID 24335489 DOI: 10.4161/Cc.27513  0.44
2014 Wheaton WW, Weinberg SE, Hamanaka RB, Soberanes S, Sullivan LB, Anso E, Glasauer A, Dufour E, Mutlu GM, Budigner GS, Chandel NS. Author response: Metformin inhibits mitochondrial complex I of cancer cells to reduce tumorigenesis Elife. DOI: 10.7554/Elife.02242.019  0.6
2013 Sullivan LB, Martinez-Garcia E, Nguyen H, Mullen AR, Dufour E, Sudarshan S, Licht JD, Deberardinis RJ, Chandel NS. The proto-oncometabolite fumarate binds glutathione to amplify ROS-dependent signaling. Molecular Cell. 51: 236-48. PMID 23747014 DOI: 10.1016/J.Molcel.2013.05.003  0.6
2012 Sullivan LB, Santos JH, Chandel NS. Mitochondria and telomeres: the promiscuous roles of TIN2. Molecular Cell. 47: 823-4. PMID 23020852 DOI: 10.1016/J.Molcel.2012.09.006  0.44
2012 Mullen AR, Wheaton WW, Jin ES, Chen PH, Sullivan LB, Cheng T, Yang Y, Linehan WM, Chandel NS, DeBerardinis RJ. Reductive carboxylation supports growth in tumour cells with defective mitochondria. Nature. 481: 385-8. PMID 22101431 DOI: 10.1038/Nature10642  0.6
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