Dale F. Mierke, Ph.D. - Publications

Chemistry Dartmouth College, Hanover, NH, United States 
Biophysical chemistry, high resolution NMR, peptide hormone structure and function

183 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Barczewski AH, Ragusa MJ, Mierke DF, Pellegrini M. Production, Crystallization, and Structure Determination of the IKK-binding Domain of NEMO. Journal of Visualized Experiments : Jove. PMID 31929506 DOI: 10.3791/60339  0.48
2019 Barczewski AH, Ragusa MJ, Mierke DF, Pellegrini M. The IKK-binding domain of NEMO is an irregular coiled coil with a dynamic binding interface. Scientific Reports. 9: 2950. PMID 30814588 DOI: 10.1038/s41598-019-39588-2  0.48
2017 Busatto N, Salvagnin U, Resentini F, Quaresimin S, Navazio L, Marin O, Pellegrini M, Costa F, Mierke DF, Trainotti L. The Peach RGF/GLV Signaling Peptide pCTG134 Is Involved in a Regulatory Circuit That Sustains Auxin and Ethylene Actions. Frontiers in Plant Science. 8: 1711. PMID 29075273 DOI: 10.3389/fpls.2017.01711  0.48
2017 Privett B, Pellegrini M, Kovacikova G, Taylor R, Skorupski K, Mierke DF, Kull FJ. Identification of a Small Molecule Activator for AphB, a LysR-Type Virulence Transcriptional Regulator in Vibrio cholerae. Biochemistry. PMID 28640592 DOI: 10.1021/acs.biochem.7b00337  0.48
2015 Gaidos G, Panaitiu AE, Guo B, Pellegrini M, Mierke DF. Identification and Characterization of the Interaction Site between cFLIPL and Calmodulin. Plos One. 10: e0141692. PMID 26529318 DOI: 10.1371/journal.pone.0141692  1
2015 Li W, Zheng S, Higgins M, Morra RP, Mendis AT, Chien CW, Ojima I, Mierke DF, Dinkova-Kostova AT, Honda T. New Monocyclic, Bicyclic, and Tricyclic Ethynylcyanodienones as Activators of the Keap1/Nrf2/ARE Pathway and Inhibitors of Inducible Nitric Oxide Synthase. Journal of Medicinal Chemistry. 58: 4738-48. PMID 25965897 DOI: 10.1021/acs.jmedchem.5b00393  1
2015 Bucur O, Gaidos G, Yatawara A, Pennarun B, Rupasinghe C, Roux J, Andrei S, Guo B, Panaitiu A, Pellegrini M, Mierke DF, Khosravi-Far R. A novel caspase 8 selective small molecule potentiates TRAIL-induced cell death. Scientific Reports. 5: 9893. PMID 25962125 DOI: 10.1038/srep09893  1
2015 Yatawara A, Gaidos G, Rupasinghe CN, O'Hara BA, Pellegrini M, Atwood WJ, Mierke DF. Small-molecule inhibitors of JC polyomavirus infection. Journal of Peptide Science : An Official Publication of the European Peptide Society. 21: 236-42. PMID 25522925 DOI: 10.1002/psc.2731  1
2015 Song GJ, Leslie KL, Barrick S, Mamonova T, Fitzpatrick JM, Drombosky KW, Peyser N, Wang B, Pellegrini M, Bauer PM, Friedman PA, Mierke DF, Bisello A. Phosphorylation of ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) by Akt promotes stability and mitogenic function of S-phase kinase-associated protein-2 (Skp2). The Journal of Biological Chemistry. 290: 2879-87. PMID 25492869 DOI: 10.1074/jbc.M114.609768  1
2015 Zheng F, Jewell H, Fitzpatrick J, Zhang J, Mierke DF, Grigoryan G. Computational design of selective peptides to discriminate between similar PDZ domains in an oncogenic pathway. Journal of Molecular Biology. 427: 491-510. PMID 25451599 DOI: 10.1016/j.jmb.2014.10.014  1
2015 Yu J, Rupasinghe C, Wilson JL, Taylor L, Rahimi N, Mierke D, Polgar P. Targeting receptor tyrosine kinases and their downstream signaling with cell-penetrating peptides in human pulmonary artery smooth muscle and endothelial cells. Chemical Biology & Drug Design. 85: 586-97. PMID 25298192 DOI: 10.1111/cbdd.12446  1
2014 Guo B, Audu CO, Cochran JC, Mierke DF, Pellegrini M. Protein engineering of the N-terminus of NEMO: structure stabilization and rescue of IKKβ binding. Biochemistry. 53: 6776-85. PMID 25286246 DOI: 10.1021/bi500861x  1
2014 Fitzpatrick JM, Pellegrini M, Cushing PR, Mierke DF. Small molecule inhibition of the Na(+)/H(+) exchange regulatory factor 1 and parathyroid hormone 1 receptor interaction. Biochemistry. 53: 5916-22. PMID 25171053 DOI: 10.1021/bi500368k  1
2014 Guo B, Gurel PS, Shu R, Higgs HN, Pellegrini M, Mierke DF. Monitoring ATP hydrolysis and ATPase inhibitor screening using (1)H NMR. Chemical Communications (Cambridge, England). 50: 12037-9. PMID 25170530 DOI: 10.1039/c4cc04399e  1
2014 O'Hara BA, Rupasinghe C, Yatawara A, Gaidos G, Mierke DF, Atwood WJ. Gallic acid-based small-molecule inhibitors of JC and BK polyomaviral infection. Virus Research. 189: 280-5. PMID 24960120 DOI: 10.1016/j.virusres.2014.06.008  1
2014 Audu CO, Plati JJ, Pellegrini M, Mierke DF. Engineering a soluble parathyroid hormone GPCR mimetic. Proteins. 82: 1370-5. PMID 24375686 DOI: 10.1002/prot.24503  1
2013 Green DS, Rupasinghe C, Warburton R, Wilson JL, Sallum CO, Taylor L, Yatawara A, Mierke D, Polgar P, Hill N. A cell permeable peptide targeting the intracellular loop 2 of endothelin B receptor reduces pulmonary hypertension in a hypoxic rat model. Plos One. 8: e81309. PMID 24312288 DOI: 10.1371/journal.pone.0081309  1
2013 Pennarun B, Gaidos G, Bucur O, Tinari A, Rupasinghe C, Jin T, Dewar R, Song K, Santos MT, Malorni W, Mierke D, Khosravi-Far R. killerFLIP: a novel lytic peptide specifically inducing cancer cell death. Cell Death & Disease. 4: e894. PMID 24176852 DOI: 10.1038/cddis.2013.401  1
2013 Audu CO, Cochran JC, Pellegrini M, Mierke DF. Recombinant production of TEV cleaved human parathyroid hormone. Journal of Peptide Science : An Official Publication of the European Peptide Society. 19: 504-10. PMID 23794508 DOI: 10.1002/psc.2528  1
2013 Fellows A, Mierke DF, Nichols RC. AUF1-RGG peptides up-regulate the VEGF antagonist, soluble VEGF receptor-1 (sFlt-1). Cytokine. 64: 337-42. PMID 23769804 DOI: 10.1016/j.cyto.2013.05.019  1
2013 Fellows A, Deng B, Mierke DF, Robey RB, Nichols RC. Peptides modeled on the RGG domain of AUF1/hnRNP-D regulate 3' UTR-dependent gene expression. International Immunopharmacology. 17: 132-41. PMID 23747316 DOI: 10.1016/j.intimp.2013.05.014  1
2013 Yatawara A, Wilson JL, Taylor L, Polgar P, Mierke DF. C-terminus of ETA/ETB receptors regulate endothelin-1 signal transmission. Journal of Peptide Science : An Official Publication of the European Peptide Society. 19: 257-62. PMID 23436727 DOI: 10.1002/psc.2499  1
2013 Yatawara AK, Hodoscek M, Mierke DF. Ligand binding site identification by higher dimension molecular dynamics. Journal of Chemical Information and Modeling. 53: 674-80. PMID 23394112 DOI: 10.1021/ci300561b  1
2012 Audu CO, O'Hara B, Pellegrini M, Wang L, Atwood WJ, Mierke DF. Reining in polyoma virus associated nephropathy: design and characterization of a template mimicking BK viral coat protein cellular binding. Biochemistry. 51: 8092-9. PMID 23002929 DOI: 10.1021/bi300639d  1
2012 Sallum CO, Wilson JL, Rupasinghe C, Berg E, Yu J, Green DS, Taylor L, Mierke D, Polgar P. Enhancing and limiting endothelin-1 signaling with a cell-penetrating peptide mimicking the third intracellular loop of the ETB receptor. Chemical Biology & Drug Design. 80: 374-81. PMID 22553998 DOI: 10.1111/j.1747-0285.2012.01405.x  1
2012 Zheng S, Santosh Laxmi YR, David E, Dinkova-Kostova AT, Shiavoni KH, Ren Y, Zheng Y, Trevino I, Bumeister R, Ojima I, Wigley WC, Bliska JB, Mierke DF, Honda T. Synthesis, chemical reactivity as Michael acceptors, and biological potency of monocyclic cyanoenones, novel and highly potent anti-inflammatory and cytoprotective agents. Journal of Medicinal Chemistry. 55: 4837-46. PMID 22533790 DOI: 10.1021/jm3003922  1
2011 Dong JZ, Shen Y, Zhang J, Tsomaia N, Mierke DF, Taylor JE. Discovery and characterization of taspoglutide, a novel analogue of human glucagon-like peptide-1, engineered for sustained therapeutic activity in type 2 diabetes. Diabetes, Obesity & Metabolism. 13: 19-25. PMID 21114599 DOI: 10.1111/j.1463-1326.2010.01313.x  1
2010 Dinkova-Kostova AT, Talalay P, Sharkey J, Zhang Y, Holtzclaw WD, Wang XJ, David E, Schiavoni KH, Finlayson S, Mierke DF, Honda T. An exceptionally potent inducer of cytoprotective enzymes: elucidation of the structural features that determine inducer potency and reactivity with Keap1. The Journal of Biological Chemistry. 285: 33747-55. PMID 20801881 DOI: 10.1074/jbc.M110.163485  1
2010 Yu J, Taylor L, Mierke D, Berg E, Shia M, Fishman J, Sallum C, Polgar P. Limiting angiotensin II signaling with a cell-penetrating peptide mimicking the second intracellular loop of the angiotensin II type-I receptor Chemical Biology and Drug Design. 76: 70-76. PMID 20492449 DOI: 10.1111/j.1747-0285.2010.00985.x  1
2010 Ahn KH, Nishiyama A, Mierke DF, Kendall DA. Hydrophobic residues in helix 8 of cannabinoid receptor 1 are critical for structural and functional properties. Biochemistry. 49: 502-11. PMID 20025243 DOI: 10.1021/bi901619r  1
2009 Ahn KH, Bertalovitz AC, Mierke DF, Kendall DA. Dual role of the second extracellular loop of the cannabinoid receptor 1: ligand binding and receptor localization. Molecular Pharmacology. 76: 833-42. PMID 19643997 DOI: 10.1124/mol.109.057356  1
2009 Kessler H, Chatterjee J, Doedens L, Operrer F, Biron E, Hoyer D, Schmid H, Gilon C, Hruby VJ, Mierkes DF. New perspective in peptide chemistry by N-alkylation. Advances in Experimental Medicine and Biology. 611: 229-31. PMID 19400173 DOI: 10.1007/978-0-387-73657-0_106  1
2009 Chatterjee J, Ovadia O, Gilon C, Hoffman A, Mierke D, Kessler H. N-methylated cyclic pentapeptides as template structures. Advances in Experimental Medicine and Biology. 611: 109-10. PMID 19400115 DOI: 10.1007/978-0-387-73657-0_48  1
2009 Ahn KH, Pellegrini M, Tsomaia N, Yatawara AK, Kendall DA, Mierke DF. Structural analysis of the human cannabinoid receptor one carboxyl-terminus identifies two amphipathic helices. Biopolymers. 91: 565-73. PMID 19274719 DOI: 10.1002/bip.21179  1
2009 Thomas BE, Sharma S, Mierke DF, Rosenblatt M. PTH and PTH antagonist induce different conformational changes in the PTHR1 receptor. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 24: 925-34. PMID 19063682 DOI: 10.1359/jbmr.081228  1
2008 Assil-Kishawi I, Samra TA, Mierke DF, Abou-Samra AB. Residue 17 of sauvagine cross-links to the first transmembrane domain of corticotropin-releasing factor receptor 1 (CRFR1). The Journal of Biological Chemistry. 283: 35644-51. PMID 18955489 DOI: 10.1074/jbc.M806351200  1
2008 Famous KR, Kumaresan V, Sadri-Vakili G, Schmidt HD, Mierke DF, Cha JH, Pierce RC. Phosphorylation-dependent trafficking of GluR2-containing AMPA receptors in the nucleus accumbens plays a critical role in the reinstatement of cocaine seeking. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 11061-70. PMID 18945913 DOI: 10.1523/JNEUROSCI.1221-08.2008  1
2008 Monaghan P, Thomas BE, Woznica I, Wittelsberger A, Mierke DF, Rosenblatt M. Mapping peptide hormone-receptor interactions using a disulfide-trapping approach. Biochemistry. 47: 5889-95. PMID 18459800 DOI: 10.1021/bi800122f  1
2008 Wittelsberger A, Mierke DF, Rosenblatt M. Mapping ligand-receptor interfaces: approaching the resolution limit of benzophenone-based photoaffinity scanning. Chemical Biology & Drug Design. 71: 380-3. PMID 18312550 DOI: 10.1111/j.1747-0285.2008.00646.x  1
2008 Thomas BE, Woznica I, Mierke DF, Wittelsberger A, Rosenblatt M. Conformational changes in the parathyroid hormone receptor associated with activation by agonist. Molecular Endocrinology (Baltimore, Md.). 22: 1154-62. PMID 18258686 DOI: 10.1210/me.2007-0520  1
2008 Chatterjee J, Mierke DF, Kessler H. Conformational preference and potential templates of N-methylated cyclic pentaalanine peptides. Chemistry (Weinheim An Der Bergstrasse, Germany). 14: 1508-17. PMID 18080261 DOI: 10.1002/chem.200701029  1
2007 Stone SR, Giragossian C, Mierke DF, Jackson GE. Further evidence for a C-terminal structural motif in CCK2 receptor active peptide hormones. Peptides. 28: 2211-22. PMID 17950490 DOI: 10.1016/j.peptides.2007.09.008  1
2007 Dugan AS, Gasparovic ML, Tsomaia N, Mierke DF, O'Hara BA, Manley K, Atwood WJ. Identification of amino acid residues in BK virus VP1 that are critical for viability and growth. Journal of Virology. 81: 11798-808. PMID 17699578 DOI: 10.1128/JVI.01316-07  1
2007 Stone SR, Mierke DF, Jackson GE. Evidence for a C-terminal structural motif in gastrin and its bioactive fragments in membrane mimetic media. Peptides. 28: 1561-71. PMID 17698249 DOI: 10.1016/j.peptides.2007.07.009  1
2007 Mierke DF, Mao L, Pellegrini M, Piserchio A, Plati J, Tsomaia N. Structural characterization of the parathyroid hormone receptor domains determinant for ligand binding. Biochemical Society Transactions. 35: 721-3. PMID 17635133 DOI: 10.1042/BST0350721  1
2007 Yu J, Lubinsky D, Tsomaia N, Huang Z, Taylor L, Mierke D, Navarro J, Miraz O, Polgar P. Activation of ERK, JNK, Akt, and G-protein coupled signaling by hybrid angiotensin II AT1/bradykinin B2 receptors expressed in HEK-293 cells. Journal of Cellular Biochemistry. 101: 192-204. PMID 17212359 DOI: 10.1002/jcb.21161  1
2007 Wolde M, Fellows A, Cheng J, Kivenson A, Coutermarsh B, Talebian L, Karlson K, Piserchio A, Mierke DF, Stanton BA, Guggino WB, Madden DR. Targeting CAL as a negative regulator of DeltaF508-CFTR cell-surface expression: an RNA interference and structure-based mutagenetic approach. The Journal of Biological Chemistry. 282: 8099-109. PMID 17158866 DOI: 10.1074/jbc.M611049200  1
2007 Plati J, Tsomaia N, Piserchio A, Mierke DF. Structural features of parathyroid hormone receptor coupled to Galpha(s)-protein. Biophysical Journal. 92: 535-40. PMID 17040990 DOI: 10.1529/biophysj.106.094813  1
2006 Chatterjee J, Mierke D, Kessler H. N-methylated cyclic pentaalanine peptides as template structures Journal of the American Chemical Society. 128: 15164-15172. PMID 17117868 DOI: 10.1021/ja063123d  1
2006 Sun X, Mierke DF, Biswas T, Lee SY, Landy A, Radman-Livaja M. Architecture of the 99 bp DNA-six-protein regulatory complex of the lambda att site. Molecular Cell. 24: 569-80. PMID 17114059 DOI: 10.1016/j.molcel.2006.10.006  1
2006 Heller M, Sukopp M, Tsomaia N, John M, Mierke DF, Reif B, Kessler H. The conformation of cyclo(-D-Pro-Ala4-) as a model for cyclic pentapeptides of the DL4 type. Journal of the American Chemical Society. 128: 13806-14. PMID 17044709 DOI: 10.1021/ja063174a  1
2006 D'Antona AM, Ahn KH, Wang L, Mierke DF, Lucas-Lenard J, Kendall DA. A cannabinoid receptor 1 mutation proximal to the DRY motif results in constitutive activity and reveals intramolecular interactions involved in receptor activation. Brain Research. 1108: 1-11. PMID 16879811 DOI: 10.1016/j.brainres.2006.05.042  1
2006 Piserchio A, Spaller M, Mierke DF. Targeting the PDZ domains of molecular scaffolds of transmembrane ion channels. The Aaps Journal. 8: E396-401. PMID 16796391 DOI: 10.1208/aapsj080245  1
2006 Gee GV, Dugan AS, Tsomaia N, Mierke DF, Atwood WJ. The role of sialic acid in human polyomavirus infections. Glycoconjugate Journal. 23: 19-26. PMID 16575519 DOI: 10.1007/s10719-006-5434-z  1
2006 Wittelsberger A, Thomas BE, Mierke DF, Rosenblatt M. Methionine acts as a "magnet" in photoaffinity crosslinking experiments. Febs Letters. 580: 1872-6. PMID 16516210 DOI: 10.1016/j.febslet.2006.02.050  1
2006 Wittelsberger A, Corich M, Thomas BE, Lee BK, Barazza A, Czodrowski P, Mierke DF, Chorev M, Rosenblatt M. The mid-region of parathyroid hormone (1-34) serves as a functional docking domain in receptor activation. Biochemistry. 45: 2027-34. PMID 16475791 DOI: 10.1021/bi051833a  1
2005 Piserchio A, Fellows A, Madden DR, Mierke DF. Association of the cystic fibrosis transmembrane regulator with CAL: structural features and molecular dynamics. Biochemistry. 44: 16158-66. PMID 16331976 DOI: 10.1021/bi0516475  1
2005 Horrigan DM, Tetreault ML, Tsomaia N, Vasileiou C, Borhan B, Mierke DF, Crouch RK, Zimmerman AL. Defining the retinoid binding site in the rod cyclic nucleotide-gated channel. The Journal of General Physiology. 126: 453-60. PMID 16230468 DOI: 10.1085/jgp.200509387  1
2005 Wang L, Piserchio A, Mierke DF. Structural characterization of the intermolecular interactions of synapse-associated protein-97 with the NR2B subunit of N-methyl-D-aspartate receptors. The Journal of Biological Chemistry. 280: 26992-6. PMID 15929985 DOI: 10.1074/jbc.M503555200  1
2005 Seck T, Pellegrini M, Florea AM, Grignoux V, Baron R, Mierke DF, Horne WC. The delta e13 isoform of the calcitonin receptor forms a six-transmembrane domain receptor with dominant-negative effects on receptor surface expression and signaling. Molecular Endocrinology (Baltimore, Md.). 19: 2132-44. PMID 15860547 DOI: 10.1210/me.2004-0472  1
2005 Yu J, Polgar P, Lubinsky D, Gupta M, Wang L, Mierke D, Taylor L. Coulombic and hydrophobic interactions in the first intracellular loop are vital for bradykinin B2 receptor ligand binding and consequent signal transduction Biochemistry. 44: 5295-5306. PMID 15807523 DOI: 10.1021/bi048288i  1
2005 Sun C, Mierke DF. Characterization of interactions of Na+/H+ exchanger regulatory factor-1 with the parathyroid hormone receptor and phospholipase C. The Journal of Peptide Research : Official Journal of the American Peptide Society. 65: 411-7. PMID 15787971 DOI: 10.1111/j.1399-3011.2005.00240.x  1
2005 Radman-Livaja M, Biswas T, Mierke D, Landy A. Architecture of recombination intermediates visualized by in-gel FRET of λ integrase-Holliday junction-arm DNA complexes Proceedings of the National Academy of Sciences of the United States of America. 102: 3913-3920. PMID 15753294 DOI: 10.1073/pnas.0500844102  1
2005 Saviano M, Isernia C, Bassarello C, Di Lello P, Galdiero S, Mierke DF, Benedetti E, Pedone C. Conformational analysis by NMR and distance geometry techniques of a peptide mimetic of the third helix of the Antennapedia homeodomain. The Journal of Peptide Research : Official Journal of the American Peptide Society. 65: 200-8. PMID 15705164 DOI: 10.1111/j.1399-3011.2005.00226.x  1
2005 Piserchio A, Zelesky V, Yu J, Taylor L, Polgar P, Mierke DF. Bradykinin B2 receptor signaling: structural and functional characterization of the C-terminus. Biopolymers. 80: 367-73. PMID 15682437 DOI: 10.1002/bip.20220  1
2004 Gee GV, Tsomaia N, Mierke DF, Atwood WJ. Modeling a sialic acid binding pocket in the external loops of JC virus VP1. The Journal of Biological Chemistry. 279: 49172-6. PMID 15347668 DOI: 10.1074/jbc.M409326200  1
2004 Yu J, Liu B, Eramian D, Mierke D, Taylor L, Polgar P. K317, R319, and E320 within the proximal C-terminus of the bradykinin B2 receptor form a motif important for phospholipase C and phospholipase A 2 but not connective tissue growth factor related signaling Journal of Cellular Biochemistry. 92: 547-559. PMID 15156566 DOI: 10.1002/jcb.20075  1
2004 Jang MK, Mierke DF, Russek SJ, Farb DH. A steroid modulatory domain on NR2B controls N-methyl-D-aspartate receptor proton sensitivity. Proceedings of the National Academy of Sciences of the United States of America. 101: 8198-203. PMID 15150412 DOI: 10.1073/pnas.0401838101  1
2004 Piserchio A, Salinas GD, Li T, Marshall J, Spaller MR, Mierke DF. Targeting specific PDZ domains of PSD-95; structural basis for enhanced affinity and enzymatic stability of a cyclic peptide. Chemistry & Biology. 11: 469-73. PMID 15123241 DOI: 10.1016/j.chembiol.2004.03.013  1
2004 Tsomaia N, Shimizu M, Shimizu N, Gardella TJ, Mierke DF. Cooperative interaction of arginine-19 and the N-terminal signaling domain in the affinity and potency of parathyroid hormone. Biochemistry. 43: 3459-70. PMID 15035617 DOI: 10.1021/bi036127t  1
2004 Giragossian C, Schaschke N, Moroder L, Mierke DF. Conformational and molecular modeling studies of beta-cyclodextrin-heptagastrin and the third extracellular loop of the cholecystokinin 2 receptor. Biochemistry. 43: 2724-31. PMID 15005607 DOI: 10.1021/bi035509w  1
2004 Tsomaia N, Pellegrini M, Hyde K, Gardella TJ, Mierke DF. Toward parathyroid hormone minimization: conformational studies of cyclic PTH(1-14) analogues. Biochemistry. 43: 690-9. PMID 14730973 DOI: 10.1021/bi035703i  1
2003 Giragossian C, Sugg EE, Szewczyk JR, Mierke DF. Intermolecular interactions between peptidic and nonpeptidic agonists and the third extracellular loop of the cholecystokinin 1 receptor. Journal of Medicinal Chemistry. 46: 3476-82. PMID 12877585 DOI: 10.1021/jm030144z  1
2003 Giragossian C, Mierke DF. Determination of ligand-receptor interactions of cholecystokinin by nuclear magnetic resonance. Life Sciences. 73: 705-13. PMID 12801592 DOI: 10.1016/S0024-3205(03)00391-6  1
2003 Pal-Ghosh R, Yu J, Prado GN, Taylor L, Mierke DF, Polgar P. Chimeric exchanges within the bradykinin B2 receptor intracellular face with the prostaglandin EP2 receptor as the donor: importance of the second intracellular loop for cAMP synthesis. Archives of Biochemistry and Biophysics. 415: 54-62. PMID 12801512 DOI: 10.1016/S0003-9861(03)00217-0  1
2002 Ulfers AL, Piserchio A, Mierke DF. Extracellular domains of the neurokinin-1 receptor: structural characterization and interactions with substance P. Biopolymers. 66: 339-49. PMID 12539262 DOI: 10.1002/bip.10312  1
2002 Piserchio A, Shimizu N, Gardella TJ, Mierke DF. Residue 19 of the parathyroid hormone: structural consequences. Biochemistry. 41: 13217-23. PMID 12403623 DOI: 10.1021/bi0261600  1
2002 Prado GN, Taylor L, Zhou X, Ricupero D, Mierke DF, Polgar P. Mechanisms regulating the expression, self-maintenance, and signaling-function of the bradykinin B2 and B1 receptors. Journal of Cellular Physiology. 193: 275-86. PMID 12384980 DOI: 10.1002/jcp.10175  1
2002 Ulfers AL, McMurry JL, Miller A, Wang L, Kendall DA, Mierke DF. Cannabinoid receptor-G protein interactions: G(alphai1)-bound structures of IC3 and a mutant with altered G protein specificity. Protein Science : a Publication of the Protein Society. 11: 2526-31. PMID 12237474 DOI: 10.1110/ps.0218402  1
2002 Ulfers AL, McMurry JL, Kendall DA, Mierke DF. Structure of the third intracellular loop of the human cannabinoid 1 receptor. Biochemistry. 41: 11344-50. PMID 12234176 DOI: 10.1021/bi0259610  1
2002 Han Y, Giragossian C, Mierke DF, Chorev M. Ni-to-Ni+ 3-ethylene-bridged partially modified retro-inverso tetrapeptide beta-turn mimetic: design, synthesis, and structural characterization. The Journal of Organic Chemistry. 67: 5085-97. PMID 12126392 DOI: 10.1021/jo011041w  1
2002 Bisello A, Chorev M, Rosenblatt M, Monticelli L, Mierke DF, Ferrari SL. Selective ligand-induced stabilization of active and desensitized parathyroid hormone type 1 receptor conformations. The Journal of Biological Chemistry. 277: 38524-30. PMID 12107160 DOI: 10.1074/jbc.M202544200  1
2002 Giragossian C, Pellegrini M, Mierke DF. NMR studies of CCK-8/CCK1 complex support membrane-associated pathway for ligand-receptor interaction. Canadian Journal of Physiology and Pharmacology. 80: 383-7. PMID 12056543 DOI: 10.1139/y02-031  1
2002 Giragossian C, Stone S, Papini AM, Moroder L, Mierke DF. Conformational and molecular modeling studies of sulfated cholecystokinin-15. Biochemical and Biophysical Research Communications. 293: 1053-9. PMID 12051766 DOI: 10.1016/S0006-291X(02)00334-0  1
2002 Yu J, Prado GN, Taylor L, Piserchio A, Gupta A, Mierke DF, Polgar P. Global chimeric exchanges within the intracellular face of the bradykinin B2 receptor with corresponding angiotensin II type Ia receptor regions: generation of fully functional hybrids showing characteristic signaling of the AT1a receptor. Journal of Cellular Biochemistry. 85: 809-19. PMID 11968020 DOI: 10.1002/jcb.10171  1
2002 Piserchio A, Han Y, Chorev M, Mierke DF. Structural characterization of a cyclic dipeptidomimetic: the effect of ring size on a 1,2,5-trisubstituted-3-oxo-1,4-diazepine system. Biopolymers. 64: 16-25. PMID 11948438 DOI: 10.1002/bip.10080  1
2002 Han Y, Mierke DF, Chorev M. Homologs of 1,2,5-hexahydro-3-one-1H-1,4-diazepine (DAP) as novel dipeptidomimetics and molecular scaffolds: efficient preparation of synthons. Biopolymers. 64: 1-15. PMID 11948437 DOI: 10.1002/bip.10079  1
2002 Giragossian C, Mierke DF. Intermolecular interactions between cholecystokinin-8 and the third extracellular loop of the cholecystokinin-2 receptor. Biochemistry. 41: 4560-6. PMID 11926817 DOI: 10.1021/bi0160009  1
2002 Monticelli L, Mammi S, Mierke DF. Molecular characterization of a ligand-tethered parathyroid hormone receptor. Biophysical Chemistry. 95: 165-72. PMID 11897155 DOI: 10.1016/S0301-4622(02)00005-4  1
2002 Piserchio A, Prado GN, Zhang R, Yu J, Taylor L, Polgar P, Mierke DF. Structural insight into the role of the second intracellular loop of the bradykinin 2 receptor in signaling and internalization. Biopolymers. 63: 239-46. PMID 11807751 DOI: 10.1002/bip.10072  1
2002 Piserchio A, Pellegrini M, Mehta S, Blackman SM, Garcia EP, Marshall J, Mierke DF. The PDZ1 domain of SAP90. Characterization of structure and binding. The Journal of Biological Chemistry. 277: 6967-73. PMID 11744724 DOI: 10.1074/jbc.M109453200  1
2001 Scheibler L, Mierke DF, Bitan G, Rosenblatt M, Chorev M. Identification of a contact domain between echistatin and the integrin alpha(v)beta(3) by photoaffinity cross-linking. Biochemistry. 40: 15117-26. PMID 11735394 DOI: 10.1021/bi0109156  1
2001 Prado GN, Mierke DF, LeBlanc T, Manseau M, Taylor L, Yu J, Zhang R, Pal-Ghosh R, Polgar P. Role of hydroxyl containing residues in the intracellular region of rat bradykinin B(2) receptor in signal transduction, receptor internalization, and resensitization. Journal of Cellular Biochemistry. 83: 435-47. PMID 11596112 DOI: 10.1002/jcb.1241  1
2001 Mierke DF, Giragossian C. Peptide hormone binding to G-protein-coupled receptors: structural characterization via NMR techniques. Medicinal Research Reviews. 21: 450-71. PMID 11579442 DOI: 10.1002/med.1018  1
2001 Macdonald D, Mierke DF, Li H, Pellegrini M, Sachais B, Krause JE, Leeman SE, Boyd ND. Photoaffinity labeling of mutant neurokinin-1 receptors reveals additional structural features of the substance P/NK-1 receptor complex. Biochemistry. 40: 2530-9. PMID 11327875 DOI: 10.1021/bi001880x  1
2001 Saviano G, Rossi F, Benedetti E, Pedone C, Mierke DF, Maione A, Zanotti G, Tancredi T, Saviano M. Structural consequences of metal complexation of cyclo[Pro-Phe-Phe-Ala-Xaa]2 decapeptides. Chemistry (Weinheim An Der Bergstrasse, Germany). 7: 1176-83. PMID 11322543 DOI: 10.1002/1521-3765(20010316)7:6<1176::AID-CHEM1176>3.0.CO;2-W  1
2001 Giragossian C, Mierke DF. Intermolecular interactions between cholecystokinin-8 and the third extracellular loop of the cholecystokinin A receptor. Biochemistry. 40: 3804-9. PMID 11300760 DOI: 10.1021/bi002659n  1
2001 Pellegrini M, Bremer AA, Ulfers AL, Boyd ND, Mierke DF. Molecular characterization of the substance P*neurokinin-1 receptor complex: development of an experimentally based model. The Journal of Biological Chemistry. 276: 22862-7. PMID 11294871 DOI: 10.1074/jbc.M101057200  1
2001 Rölz C, Mierke DF. Characterization of the molecular motions of constitutively active G protein-coupled receptors for parathyroid hormone. Biophysical Chemistry. 89: 119-28. PMID 11254206 DOI: 10.1016/S0301-4622(00)00222-2  1
2001 Giragossian C, Nardi E, Savery C, Pellegrini M, Meini S, Maggi CA, Papini AM, Mierke DF. Structural characterization of lipopeptide agonists for the bradykinin B2 receptor. Biopolymers. 58: 511-20. PMID 11241222 DOI: 10.1002/1097-0282(20010415)58:5<511::AID-BIP1026>3.0.CO;2-Z  1
2001 Rovero P, Pellegrini M, Di Fenza A, Meini S, Quartara L, Maggi CA, Formaggio F, Toniolo C, Mierke DF. Agonist activity at the kinin B1 receptor: structural requirements of the central tetrapeptide. Journal of Medicinal Chemistry. 44: 274-8. PMID 11170638 DOI: 10.1021/jm000319u  1
2000 Pellegrini M, Liehr S, Fisher AL, Laub PB, Cooperman BS, Mierke DF. Structure-based optimization of peptide inhibitors of mammalian ribonucleotide reductase. Biochemistry. 39: 12210-5. PMID 11015199 DOI: 10.1021/bi001323a  1
2000 Bitan G, Scheibler L, Mierke DF, Rosenblatt M, Chorev M. Ligand-integrin alpha v beta 3 interaction determined by photoaffinity cross-linking: a challenge to the prevailing model. Biochemistry. 39: 11014-23. PMID 10998238 DOI: 10.1021/bi000877a  1
2000 Piserchio A, Bisello A, Rosenblatt M, Chorev M, Mierke DF. Characterization of parathyroid hormone/receptor interactions: structure of the first extracellular loop. Biochemistry. 39: 8153-60. PMID 10889021 DOI: 10.1021/bi000196f  1
2000 Greenberg Z, Bisello A, Mierke DF, Rosenblatt M, Chorev M. Mapping the bimolecular interface of the parathyroid hormone (PTH)-PTH1 receptor complex: spatial proximity between Lys(27) (of the hormone principal binding domain) and leu(261) (of the first extracellular loop) of the human PTH1 receptor. Biochemistry. 39: 8142-52. PMID 10889020 DOI: 10.1021/bi000195n  1
2000 Piserchio A, Usdin T, Mierke DF. Structure of tuberoinfundibular peptide of 39 residues. The Journal of Biological Chemistry. 275: 27284-90. PMID 10856302 DOI: 10.1074/jbc.M003869200  1
1999 Pellegrini M, Mierke DF. Molecular complex of cholecystokinin-8 and N-terminus of the cholecystokinin A receptor by NMR spectroscopy. Biochemistry. 38: 14775-83. PMID 10555959 DOI: 10.1021/bi991272l  1
1999 Pellegrini M, Mierke DF. Structural characterization of peptide hormone/receptor interactions by NMR spectroscopy. Biopolymers. 51: 208-20. PMID 10516572 DOI: 10.1002/(SICI)1097-0282(1999)51:3<208::AID-BIP4>3.0.CO;2-U  1
1999 Pellegrini M, Tancredi M, Rovero P, Mierke DF. Probing the topological arrangement of the N- and C-terminal residues of bradykinin for agonist activity at the B1 receptor. Journal of Medicinal Chemistry. 42: 3369-77. PMID 10464023 DOI: 10.1021/jm9901069  1
1999 Rölz C, Pellegrini M, Mierke DF. Molecular characterization of the receptor-ligand complex for parathyroid hormone. Biochemistry. 38: 6397-405. PMID 10350457 DOI: 10.1021/bi9829276  1
1999 Mierke DF, Pellegrini M. Parathyroid hormone and parathyroid hormone-related protein: model systems for the development of an osteoporosis therapy. Current Pharmaceutical Design. 5: 21-36. PMID 10066882  1
1999 Mierke DF. Models for understanding and predicting protein structure Theoretical and Computational Chemistry. 6: 637-653. DOI: 10.1016/S1380-7323(99)80027-2  1
1998 Prado GN, Mierke DF, Pellegrini M, Taylor L, Polgar P. Motif mutation of bradykinin B2 receptor second intracellular loop and proximal C terminus is critical for signal transduction, internalization, and resensitization. The Journal of Biological Chemistry. 273: 33548-55. PMID 9837936 DOI: 10.1074/jbc.273.50.33548  1
1998 Pellegrini M, Bisello A, Rosenblatt M, Chorev M, Mierke DF. Binding domain of human parathyroid hormone receptor: from conformation to function. Biochemistry. 37: 12737-43. PMID 9737850 DOI: 10.1021/bi981265h  1
1998 Bisello A, Adams AE, Mierke DF, Pellegrini M, Rosenblatt M, Suva LJ, Chorev M. Parathyroid hormone-receptor interactions identified directly by photocross-linking and molecular modeling studies. The Journal of Biological Chemistry. 273: 22498-505. PMID 9712875 DOI: 10.1074/jbc.273.35.22498  1
1998 Grdadolnik SG, Pristovsek P, Mierke DF. Vancomycin: conformational consequences of the sugar substituent. Journal of Medicinal Chemistry. 41: 2090-9. PMID 9622550 DOI: 10.1021/jm9705972  1
1998 Mierke DF. Therapeutic approaches for sticky situations. IBC Conference on Integrins: applying multidisciplinary approaches for targeted therapies. Cambridge, MA, USA, 29-30 January 1998. Molecular Medicine Today. 4: 194-5. PMID 9612797 DOI: 10.1016/S1357-4310(98)01248-9  1
1998 Pellegrini M, Royo M, Rosenblatt M, Chorev M, Mierke DF. Addressing the tertiary structure of human parathyroid hormone-(1-34). The Journal of Biological Chemistry. 273: 10420-7. PMID 9553100 DOI: 10.1074/jbc.273.17.10420  1
1998 Armand P, Kirshenbaum K, Goldsmith RA, Farr-Jones S, Barron AE, Truong KT, Dill KA, Mierke DF, Cohen FE, Zuckermann RN, Bradley EK. NMR determination of the major solution conformation of a peptoid pentamer with chiral side chains. Proceedings of the National Academy of Sciences of the United States of America. 95: 4309-14. PMID 9539733 DOI: 10.1073/pnas.95.8.4309  1
1998 Mierke DF. Overlapping ensemble dynamics: A method for structure calculations of multiple configurational isomers Journal of the American Chemical Society. 120: 10721-10723. DOI: 10.1021/ja974090s  1
1998 Weitz IS, Pellegrini M, Royo M, Mierke DF, Chorev M. 1,2,5-Trisubstituted 1,4-diazepine-3-one: A novel dipeptidomimetic molecular scaffold Letters in Peptide Science. 5: 83-86.  1
1998 Pellegrini M, Weitz I, Chorev M, Mierke DF. Conformational investigation of a novel, dipeptide based molecular scaffold Letters in Peptide Science. 5: 151-153.  1
1998 Benedetti E, Isernia C, Nastri F, Pedone C, Saviano M, Mierke DF, Melchiorri P, Negri L, Potenza RL, Severini C, Erspamer V. Conformational analysis by NMR and distance-geometry techniques of deltorphin analogs European Journal of Organic Chemistry. 2279-2287.  1
1997 Weitz IS, Pellegrini M, Mierke DF, Chorev M. Synthesis of a Trisubstituted 1,4-Diazepin-3-one-Based Dipeptidomimetic as a Novel Molecular Scaffold. The Journal of Organic Chemistry. 62: 2527-2534. PMID 11671593 DOI: 10.1021/jo962257e  1
1997 Mercurio E, Pellegrini M, Mierke DF. Structure, dynamics, and topological orientation of the polyether, ionophore antibiotic monensin, in a micellar environment. Biopolymers. 42: 759-69. PMID 10904548 DOI: 10.1002/(SICI)1097-0282(199712)42:7<759::AID-BIP2>3.0.CO;2-S  1
1997 Grdadolnik SG, Mierke DF. Structural characterization of the molecular dimer of the peptide antibiotic vancomycin by distance geometry in four spatial dimensions Journal of Chemical Information and Computer Sciences. 37: 1044-1047. PMID 9392857  1
1997 Grdadolnik SG, Mierke DF, Carlson GH. Vancomycin: Interactions with a model cell membrane Biopolymers. 42: 627-632. PMID 9358729 DOI: 10.1002/(SICI)1097-0282(199711)42:6<627::AID-BIP1>3.0.CO;2-W  1
1997 Pellegrini M, Bisello A, Rosenblatt M, Chorev M, Mierke DF. Conformational studies of RS-66271, an analog of parathyroid hormone- related protein with pronounced bone anabolic activity Journal of Medicinal Chemistry. 40: 3025-3031. PMID 9301664 DOI: 10.1021/jm970181o  1
1997 Mierke DF, Maretto S, Schievano E, DeLuca D, Bisello A, Mammi S, Rosenblatt M, Peggion E, Chorev M. Conformational studies of mono- and bicyclic parathyroid hormone- related protein-derived agonists Biochemistry. 36: 10372-10383. PMID 9265617 DOI: 10.1021/bi970771o  1
1997 Pellegrini M, Royo M, Chorev M, Mierke DF. Conformational consequences of i, i+3 cystine linkages: Nucleation for α-helicity? Journal of Peptide Research. 49: 404-414. PMID 9211221  1
1997 Maretto S, Mammi S, Bissacco E, Peggion E, Bisello A, Rosenblatt M, Chorev M, Mierke DF. Mono- and bicyclic analogs of parathyroid hormone-related protein. 2. Conformational analysis of antagonists by CD, NMR, and distance geometry calculations Biochemistry. 36: 3300-3307. PMID 9116008 DOI: 10.1021/bi9619031  1
1997 Pellegrini M, Mierke DF. Threonine 6-bradykinin: Molecular dynamics simulations in a biphasic membrane mimetic Journal of Medicinal Chemistry. 40: 99-104. PMID 9016333 DOI: 10.1021/jm9605389  1
1997 Pellegrini M, Mammi S, Peggion E, Mierke DF. Threonine 6-bradykinin: Structural characterization in the presence of micelles by nuclear magnetic resonance and distance geometry Journal of Medicinal Chemistry. 40: 92-98. PMID 9016332 DOI: 10.1021/jm9605391  1
1997 Pellegrini M, Weitz IS, Chorev M, Mierke DF. A trisubstituted 1,4-diazepine-3-one-based dipeptidomimetic: Conformational characterization by NMR and computer simulation Journal of the American Chemical Society. 119: 2430-2436. DOI: 10.1021/ja963144f  1
1996 Pellegrini M, Royo M, Chorev M, Mierke DF. Conformational characterization of a peptide mimetic of the third cytoplasmic loop of the G-protein coupled parathyroid hormone/parathyroid hormone related protein receptor Biopolymers - Peptide Science Section. 40: 653-666. PMID 9140202 DOI: 10.1002/(SICI)1097-0282(1996)40:6<653::AID-BIP5>3.0.CO;2-V  1
1996 Pellegrini M, Gobbo M, Rocchi R, Peggion E, Mammi S, Mierke DF. Threonine6-bradykinin: Conformational study of a flexible peptide in dimethyl sulfoxide by nmr and ensemble calculations Biopolymers - Peptide Science Section. 40: 561-569. PMID 9101761 DOI: 10.1002/(SICI)1097-0282(1996)40:5<561::AID-BIP14>3.0.CO;2-K  1
1996 Markert RLM, Ruppach H, Gehring S, Dietrich U, Mierke DF, Köck M, Rübsamen-Waigmann H, Griesinger C. Secondary structural elements as a basis for antibody recognition in the immunodominant region of human immunodeficiency viruses 1 and 2 European Journal of Biochemistry. 237: 188-204. PMID 8620873  1
1996 Mierke DF, Royo M, Pellegrini M, Sun H, Chorev M. Peptide mimetic of the third cytoplasmic loop of the PTH/PTHrP receptor Journal of the American Chemical Society. 118: 8998-9004. DOI: 10.1021/ja960454p  1
1995 Mierke DF, Rudolph-Bohner S, Muller G, Moroder L. Structure of two microcystins: Refinement with nuclear Overhauser effects and ensemble calculations Biopolymers. 36: 811-828. DOI: 10.1002/bip.360360613  1
1995 Eberstadt M, Guba W, Kessler H, Kogler H, Mierke DF. Conformation and dynamics of dimeric ureido-balhimycin Biopolymers. 36: 429-437. DOI: 10.1002/bip.360360406  1
1995 Eberstadt M, Gemmecker G, Mierke DF, Kessler H. Scalar coupling constants - Their analysis and their application for the elucidation of structures Angewandte Chemie (International Edition in English). 34: 1671-1695.  1
1994 Rudolph-Böhner S, Mierke DF, Moroder L. Molecular structure of the cyanobacterial tumor-promoting microcystins Febs Letters. 349: 319-323. PMID 8050589 DOI: 10.1016/0014-5793(94)00680-6  1
1994 Jahnke W, Mierke DF, Beress L, Kessler H. Structure of cobra cardiotoxin CTXI as derived from nuclear magnetic resonance spectroscopy and distance geometry calculations Journal of Molecular Biology. 240: 445-458. PMID 8046750 DOI: 10.1006/jmbi.1994.1460  1
1994 Mierke DF, Huber T, Kessler H. Coupling constants again: Experimental restraints in structure refinement Journal of Computer-Aided Molecular Design. 8: 29-40. PMID 8035210 DOI: 10.1007/BF00124347  1
1994 Mierke DF, Geyer A, Kessler H. Coupling constants and hydrogen bonds as experimental restraints in a distance geometry refinement protocol International Journal of Peptide and Protein Research. 44: 325-331. PMID 7875934  1
1994 Grdadolnik SG, Mierke DF, Byk G, Zeltser I, Gilon C, Kessler H. Comparison of the conformation of active and nonactive backbone cyclic analogs of substance P as a tool to elucidate features of the bioactive conformation: NMR and molecular dynamics in DMSO and water. Journal of Medicinal Chemistry. 37: 2145-52. PMID 7518522  1
1994 Mierke DF, Kurz M, Kessler H. Peptide flexibility and calculations of an ensemble of molecules Journal of the American Chemical Society. 116: 1042-1049.  1
1994 Mierke DF, Scheek RM, Kessler H. Coupling constants as restraints in ensemble distance driven dynamics Biopolymers. 34: 559-563.  1
1993 Moroder L, Musiol HJ, Kocher K, Bali JP, Schneider CH, Guba W, Muller G, Mierke DF, Kessler H. Synthetic immunogens. The effect of the conformational space on biological and immunological responses to dimeric hormone constructs European Journal of Biochemistry. 212: 325-333. PMID 8444171  1
1993 Mierke DF, Kessler H. Improved molecular dynamics simulations for the determination of peptide structures Biopolymers. 33: 1003-1017. PMID 8343582  1
1993 Van Oijen AH, Behrens S, Mierke DF, Kessler H, Van Boom JH, Liskamp RMJ. Synthesis and structure of cyclic phosphopeptides containing a phosphodiester linkage Journal of Organic Chemistry. 58: 3722-3730.  1
1993 Konat RK, Mierke DF, Kessler H, Kutscher B, Bernd M, Voegeli R. Synthesis and solvent effects on the conformation of hymenistatin 1 Helvetica Chimica Acta. 76: 1649-1666.  1
1992 Kessler H, Mierke DF, Saulitis J, Seip S, Steuernagel S, Wein T, Will M. The structure of Ro 09-0198 in different environments Biopolymers. 32: 427-433. PMID 1623138 DOI: 10.1002/bip.360320420  1
1992 Yamazaki T, Mierke DF, Said-Nejad OE, Felder ER, Goodman M. 14-membered cyclic opioids related to dermorphin and their partially retro-inverso modified analogues. II. Preferred conformations in solution as studied by 1H-NMR spectroscopy. International Journal of Peptide and Protein Research. 39: 161-81. PMID 1517015  1
1992 Said-Nejad OE, Felder ER, Mierke DF, Yamazaki T, Schiller PW, Goodman M. 14-membered cyclic opioids related to dermorphin and their partially retro-inverso modified analogues. I. Synthesis and biological activity. International Journal of Peptide and Protein Research. 39: 145-60. PMID 1517014  1
1992 Mierke DF, Kessler H. Combined use of homo- and heteronuclear coupling constants as restraints in molecular dynamics simulations Biopolymers. 32: 1277-1282. PMID 1420958  1
1992 Mierke DF, Durr H, Kessler H, Jung G. Neuropeptide Y. Optimized solid-phase synthesis and conformational analysis in trifluoroethanol European Journal of Biochemistry. 206: 39-48. PMID 1316841 DOI: 10.1111/j.1432-1033.1992.tb16899.x  1
1992 Saulitis J, Mierke DF, Byk G, Gilon C, Kessler H. Conformation of cyclic analogues of substance P: NMR and molecular dynamics in dimethyl sulfoxide Journal of the American Chemical Society. 114: 4818-4827. DOI: 10.1021/ja00038a054  1
1992 Eberstadt M, Mierke DF, Kock M, Kessler H. Peptide conformation from coupling constants: Scalar couplings as restraints in MD simulations Helvetica Chimica Acta. 75: 2583-2592. DOI: 10.1002/hlca.19920750813  1
1992 Mierke DF, Reggelin M. Simultaneous determination of conformation and configuration using distance geometry Journal of Organic Chemistry. 57: 6365-6367.  1
1992 Reggelin M, Hoffmann H, Köck M, Mierke DF. Determination of conformation and relative configuration of a small, rapidly tumbling molecule in solution by combined application of NOESY and restrained MD calculations Journal of the American Chemical Society. 114: 3272-3277.  1
1992 Mierke DF, Grdadolnik SG, Kessler H. Use of one-bond Cα-Hα coupling constants as restraints in MD simulations Journal of the American Chemical Society. 114: 8283-8284.  1
1992 Kurz M, Mierke DF, Kessler H. Calculation of molecular dynamics for peptides in dimethyl sulfoxide: Elimination of vacuum effects Angewandte Chemie (International Edition in English). 31: 210-212.  1
1991 Goodman M, Sald-Nejad OE, Felder E, Mierke DF, Yamazaki T, Schiller PW. Peptidomimetic opioids--synthesis, spectroscopy, and computer simulations. Nida Research Monograph. 112: 218-38. PMID 1754000  1
1991 Mierke DF, Kessler H. Molecular dynamics with dimethyl sulfoxide as a solvent. Conformation of a cyclic hexapeptide Journal of the American Chemical Society. 113: 9466-9470.  1
1991 Kessler H, Mierke DF, Donald D, Furber M. Toward the understanding of immunosuppression Angewandte Chemie - International Edition in English. 30: 954-955.  1
1991 Mierke DF, Schmieder P, Karuso P, Kessler H. Conformational analysis of the cis- and trans-isomers of FK506 by NMR and molecular dynamics Helvetica Chimica Acta. 74: 1027-1047.  1
1990 Mierke DF, Schiller PW, Goodman M. A conformational comparison of two stereoisomeric cyclic dermorphin analogues employing NMR and computer simulations. Biopolymers. 29: 943-52. PMID 2369622 DOI: 10.1002/bip.360290607  1
1990 Mierke DF, Nössner G, Schiller PW, Goodman M. Morphiceptin analogs containing 2-aminocyclopentane carboxylic acid as a peptidomimetic for proline. International Journal of Peptide and Protein Research. 35: 35-45. PMID 2323882  1
1990 Bairaktari E, Mierke DF, Mammi S, Peggion E. Conformations of bombolitins I and III in aqueous solutions: Circular dichroism,1H NMR, and computer simulation studies Biochemistry®. 29: 10097-10102. PMID 2271640  1
1990 Bairaktari E, Mierke DF, Mammi S, Peggion E. Conformational studies by circular dichroism,1H NMR, and computer simulations of bombolitins i and iii in aqueous solution containing surfactant micelles Biochemistry®. 29: 10090-10096. PMID 2271639  1
1990 Mierke DF, Said-Nejad OE, Schiller PW, Goodman M. Enkephalin analogues containing beta-naphthylalanine at the fourth position. Biopolymers. 29: 179-96. PMID 2158358 DOI: 10.1002/bip.360290123  1
1990 Mierke DF, Pattaroni C, Delaet N, Toy A, Goodman M, Tancredi T, Motta A, Temussi PA, Moroder L, Bovermann G. Cyclic hexapeptides related to somatostatin. Conformational analysis employing 1H-NMR and molecular dynamics. International Journal of Peptide and Protein Research. 36: 418-32. PMID 1980490  1
1990 Karuso P, Kessler H, Mierke DF. Solution structure of FK 506 from nuclear magnetic resonance and molecular dynamics Journal of the American Chemical Society. 112: 9434-9436. DOI: 10.1021/ja00181a078  1
1990 Benedetti E, Di Blasio B, Pavone V, Pedone C, Fuller WD, Mierke DF, Goodman M. Crystal structure of two retro-inverso sweeteners Journal of the American Chemical Society. 112: 8909-8912.  1
1990 Bairaktari E, Mierke DF, Mammi S, Peggion E. Observation of a cis amide isomer within a linear peptide Journal of the American Chemical Society. 112: 5383.  1
1989 Palmer DE, Mierke DF, Pattaroni C, Goodman M, Wakamiya T, Fukase K, Kitazawa M, Fujita H, Shiba T. Interactive NMR and computer simulation studies of lanthionine-ring structures. Biopolymers. 28: 397-408. PMID 2720116 DOI: 10.1002/bip.360280137  1
1989 Goodman M, Mierke DF. Configurations of morphiceptins by 1H and 13C NMR spectroscopy Journal of the American Chemical Society. 111: 3489-3496.  1
1989 Mierke DF, Yamazaki T, Said-Nejad OE, Felder ER, Goodman M. Cis/trans isomers in cyclic peptides without N-substituted amides Journal of the American Chemical Society. 111: 6847-6849.  1
1988 Mapelli C, Stammer CH, Lok S, Mierke DF, Goodman M. Synthesis, taste properties, and conformational analysis of four stereoisomeric cyclopropane analogs of aspartame. International Journal of Peptide and Protein Research. 32: 484-95. PMID 3246476  1
1987 Venkatachalapathi YV, Mierke DF, Taulane JP, Goodman M. Gas-phase IR spectra of substituted alkylamides. Biopolymers. 26: 763-73. PMID 3593891 DOI: 10.1002/bip.360260514  1
1987 Mierke DF, Lucietto P, Goodman M, Schiller PW. Conformational studies of diastereomeric cyclic enkephalins by 1H-NMR and computer simulations. Biopolymers. 26: 1573-86. PMID 2822165 DOI: 10.1002/bip.360260909  1
1987 Goodman M, Coddington J, Mierke DF, Fuller WD. A model for the sweet taste of stereoisomeric retro-inverso and dipeptide amides Journal of the American Chemical Society. 109: 4712-4714.  1
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