Year |
Citation |
Score |
2019 |
Pattabhi S, Lotti SN, Berger MP, Singh S, Lux CT, Jacoby K, Lee C, Negre O, Scharenberg AM, Rawlings DJ. In Vivo Outcome of Homology-Directed Repair at the HBB Gene in HSC Using Alternative Donor Template Delivery Methods. Molecular Therapy. Nucleic Acids. 17: 277-288. PMID 31279229 DOI: 10.1016/J.Omtn.2019.05.025 |
0.675 |
|
2019 |
Lux CT, Pattabhi S, Berger M, Nourigat C, Flowers DA, Negre O, Humbert O, Yang JG, Lee C, Jacoby K, Bernstein I, Kiem HP, Scharenberg A, Rawlings DJ. TALEN-Mediated Gene Editing of in Human Hematopoietic Stem Cells Leads to Therapeutic Fetal Hemoglobin Induction. Molecular Therapy. Methods & Clinical Development. 12: 175-183. PMID 30705922 DOI: 10.1016/J.Omtm.2018.12.008 |
0.599 |
|
2017 |
Jacoby K, Lambert AR, Scharenberg AM. Characterization of homing endonuclease binding and cleavage specificities using yeast surface display SELEX (YSD-SELEX). Nucleic Acids Research. 45: e11. PMID 28180328 DOI: 10.1093/Nar/Gkw864 |
0.669 |
|
2017 |
Lux C, Jacoby K, Pattabhi S, Yang J, Humbert O, Gordon B, Bernstein ID, Rawlings DJ, Scharenberg AM. Talen Mediated Therapeutic Gene Editing Strategy for ß-Hemoglobinopathies Blood. 130: 3340-3340. DOI: 10.1182/Blood.V130.Suppl_1.3340.3340 |
0.426 |
|
2016 |
Gwiazda KS, Grier AE, Sahni J, Burleigh SM, Martin U, Yang JG, Popp NA, Krutein MC, Khan IF, Jacoby K, Jensen MC, Rawlings DJ, Scharenberg AM. High efficiency CRISPR/Cas9-mediated gene editing in primary human T-cells using mutant adenoviral E4orf6/E1b55k "helper" proteins. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 27203437 DOI: 10.1038/Mt.2016.105 |
0.675 |
|
2016 |
Grier AE, Burleigh S, Sahni J, Clough CA, Cardot V, Choe DC, Krutein MC, Rawlings DJ, Jensen MC, Scharenberg AM, Jacoby K. pEVL: A Linear Plasmid for Generating mRNA IVT Templates With Extended Encoded Poly(A) Sequences. Molecular Therapy. Nucleic Acids. 5: e306. PMID 27093168 DOI: 10.1038/Mtna.2016.21 |
0.594 |
|
2014 |
Jacoby K, Scharenberg AM. Homing endonuclease target determination using SELEX adapted for yeast surface display. Methods in Molecular Biology (Clifton, N.J.). 1123: 165-90. PMID 24510268 DOI: 10.1007/978-1-62703-968-0_13 |
0.685 |
|
2012 |
Certo MT, Gwiazda KS, Kuhar R, Sather B, Curinga G, Mandt T, Brault M, Lambert AR, Baxter SK, Jacoby K, Ryu BY, Kiem HP, Gouble A, Paques F, Rawlings DJ, et al. Coupling endonucleases with DNA end-processing enzymes to drive gene disruption. Nature Methods. 9: 973-5. PMID 22941364 DOI: 10.1038/Nmeth.2177 |
0.585 |
|
2012 |
Jacoby K, Metzger M, Shen BW, Certo MT, Jarjour J, Stoddard BL, Scharenberg AM. Expanding LAGLIDADG endonuclease scaffold diversity by rapidly surveying evolutionary sequence space. Nucleic Acids Research. 40: 4954-64. PMID 22334611 DOI: 10.1093/Nar/Gkr1303 |
0.723 |
|
2011 |
Takeuchi R, Lambert AR, Mak AN, Jacoby K, Dickson RJ, Gloor GB, Scharenberg AM, Edgell DR, Stoddard BL. Tapping natural reservoirs of homing endonucleases for targeted gene modification. Proceedings of the National Academy of Sciences of the United States of America. 108: 13077-82. PMID 21784983 DOI: 10.1073/Pnas.1107719108 |
0.735 |
|
2008 |
Aoki SK, Malinverni JC, Jacoby K, Thomas B, Pamma R, Trinh BN, Remers S, Webb J, Braaten BA, Silhavy TJ, Low DA. Contact-dependent growth inhibition requires the essential outer membrane protein BamA (YaeT) as the receptor and the inner membrane transport protein AcrB. Molecular Microbiology. 70: 323-40. PMID 18761695 DOI: 10.1111/J.1365-2958.2008.06404.X |
0.314 |
|
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