Kerry L. Fillgrove, Ph.D. - Publications

2001 Case Western Reserve University School of Medicine, Cleveland, OH, United States 

13 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Pero JE, Rossi MA, Kelly MJ, Lehman HD, Layton ME, Garbaccio RM, O'Brien JA, Magliaro BC, Uslaner JM, Huszar SL, Fillgrove KL, Tang C, Kuo Y, Joyce LA, Sherer EC, et al. Optimization of Novel Aza-benzimidazolone mGluR2 PAMs with Respect to LLE and PK Properties and Mitigation of CYP TDI. Acs Medicinal Chemistry Letters. 7: 312-7. PMID 26985321 DOI: 10.1021/acsmedchemlett.5b00459  0.52
2016 Layton ME, Reif AJ, Hartingh TJ, Rodzinak K, Dudkin V, Wang C, Arrington K, Kelly MJ, Garbaccio RM, O'Brien JA, Magliaro BC, Uslaner JM, Huszar SL, Fillgrove KL, Tang C, et al. Discovery of 5-aryl-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-ones as positive allosteric modulators of metabotropic glutamate subtype-2 (mGlu2) receptors with efficacy in a preclinical model of psychosis. Bioorganic & Medicinal Chemistry Letters. PMID 26810316 DOI: 10.1016/j.bmcl.2016.01.021  0.52
2010 Garbaccio RM, Brnardic EJ, Fraley ME, Hartman GD, Hutson PH, O'Brien JA, Magliaro BC, Uslaner JM, Huszar SL, Fillgrove KL, Small JH, Tang C, Kuo Y, Jacobson MA. Discovery of Oxazolobenzimidazoles as Positive Allosteric Modulators for the mGluR2 Receptor. Acs Medicinal Chemistry Letters. 1: 406-10. PMID 24900224 DOI: 10.1021/ml100115a  0.52
2010 Brnardic EJ, Fraley ME, Garbaccio RM, Layton ME, Sanders JM, Culberson C, Jacobson MA, Magliaro BC, Hutson PH, O'Brien JA, Huszar SL, Uslaner JM, Fillgrove KL, Tang C, Kuo Y, et al. 3-Aryl-5-phenoxymethyl-1,3-oxazolidin-2-ones as positive allosteric modulators of mGluR2 for the treatment of schizophrenia: Hit-to-lead efforts. Bioorganic & Medicinal Chemistry Letters. 20: 3129-33. PMID 20409708 DOI: 10.1016/j.bmcl.2010.03.089  0.52
2008 Tiller PR, Yu S, Castro-Perez J, Fillgrove KL, Baillie TA. High-throughput, accurate mass liquid chromatography/tandem mass spectrometry on a quadrupole time-of-flight system as a 'first-line' approach for metabolite identification studies. Rapid Communications in Mass Spectrometry : Rcm. 22: 1053-61. PMID 18327855 DOI: 10.1002/rcm.3472  0.52
2007 Fillgrove KL, Pakhomova S, Schaab MR, Newcomer ME, Armstrong RN. Structure and mechanism of the genomically encoded fosfomycin resistance protein, FosX, from Listeria monocytogenes. Biochemistry. 46: 8110-20. PMID 17567049 DOI: 10.1021/bi700625p  0.52
2005 Rigsby RE, Fillgrove KL, Beihoffer LA, Armstrong RN. Fosfomycin resistance proteins: a nexus of glutathione transferases and epoxide hydrolases in a metalloenzyme superfamily. Methods in Enzymology. 401: 367-79. PMID 16399398 DOI: 10.1016/S0076-6879(05)01023-2  0.52
2004 Rigsby RE, Rife CL, Fillgrove KL, Newcomer ME, Armstrong RN. Phosphonoformate: a minimal transition state analogue inhibitor of the fosfomycin resistance protein, FosA. Biochemistry. 43: 13666-73. PMID 15504029 DOI: 10.1021/bi048767h  0.52
2003 Fillgrove KL, Pakhomova S, Newcomer ME, Armstrong RN. Mechanistic diversity of fosfomycin resistance in pathogenic microorganisms. Journal of the American Chemical Society. 125: 15730-1. PMID 14677948 DOI: 10.1021/ja039307z  0.52
2002 Liu B, Wang Y, Fillgrove KL, Anderson VE. Triclosan inhibits enoyl-reductase of type I fatty acid synthase in vitro and is cytotoxic to MCF-7 and SKBr-3 breast cancer cells. Cancer Chemotherapy and Pharmacology. 49: 187-93. PMID 11935210 DOI: 10.1007/s00280-001-0399-x  0.52
2001 Fillgrove KL, Anderson VE. The mechanism of dienoyl-CoA reduction by 2,4-dienoyl-CoA reductase is stepwise: observation of a dienolate intermediate. Biochemistry. 40: 12412-21. PMID 11591162 DOI: 10.1021/bi0111606  0.52
2000 Fillgrove KL, Anderson VE. Orientation of coenzyme A substrates, nicotinamide and active site functional groups in (Di)enoyl-coenzyme A reductases. Biochemistry. 39: 7001-11. PMID 10841782 DOI: 10.1021/bi0000566  0.52
1999 Fillgrove KL, Anderson VE, Mizugaki M. Cloning, expression, and purification of the functional 2,4-dienoyl-CoA reductase from rat liver mitochondria. Protein Expression and Purification. 17: 57-63. PMID 10497069 DOI: 10.1006/prep.1999.1101  0.52
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