| Year |
Citation |
Score |
| 2025 |
Seydoux G. From embryos to condensates: A developmental biologist's journey. Journal of Molecular Biology. 169083. PMID 40086688 DOI: 10.1016/j.jmb.2025.169083 |
0.32 |
|
| 2024 |
Scholl A, Liu Y, Seydoux G. Caenorhabditis elegans germ granules accumulate hundreds of low translation mRNAs with no systematic preference for germ cell fate regulators. Development (Cambridge, England). 151. PMID 38984542 DOI: 10.1242/dev.202575 |
0.354 |
|
| 2022 |
Cassani M, Seydoux G. Specialized germline P-bodies are required to specify germ cell fate in C. elegans embryos. Development (Cambridge, England). PMID 36196602 DOI: 10.1242/dev.200920 |
0.39 |
|
| 2021 |
Schmidt H, Putnam A, Rasoloson D, Seydoux G. Protein-based condensation mechanisms drive the assembly of RNA-rich P granules. Elife. 10. PMID 34106046 DOI: 10.7554/eLife.63698 |
0.321 |
|
| 2020 |
Lee CS, Putnam A, Lu T, He S, Ouyang JPT, Seydoux G. Recruitment of mRNAs to P granules by condensation with intrinsically-disordered proteins. Elife. 9. PMID 31975687 DOI: 10.7554/Elife.52896 |
0.401 |
|
| 2020 |
Lee CS, Putnam A, Lu T, He S, Ouyang JPT, Seydoux G. Author response: Recruitment of mRNAs to P granules by condensation with intrinsically-disordered proteins Elife. DOI: 10.7554/Elife.52896.Sa2 |
0.32 |
|
| 2019 |
Ouyang JPT, Folkmann A, Bernard L, Lee CY, Seroussi U, Charlesworth AG, Claycomb JM, Seydoux G. P Granules Protect RNA Interference Genes from Silencing by piRNAs. Developmental Cell. PMID 31402283 DOI: 10.1016/J.Devcel.2019.07.026 |
0.385 |
|
| 2019 |
Cable J, Brangwynne C, Seydoux G, Cowburn D, Pappu RV, Castañeda CA, Berchowitz LE, Chen Z, Jonikas M, Dernburg A, Mittag T, Fawzi NL. Phase separation in biology and disease-a symposium report. Annals of the New York Academy of Sciences. PMID 31199001 DOI: 10.1111/Nyas.14126 |
0.345 |
|
| 2019 |
Putnam A, Cassani M, Smith J, Seydoux G. A gel phase promotes condensation of liquid P granules in Caenorhabditis elegans embryos. Nature Structural & Molecular Biology. PMID 30833787 DOI: 10.1038/S41594-019-0193-2 |
0.355 |
|
| 2019 |
Folkmann AW, Seydoux G. Spatial regulation of the polarity kinase PAR-1 by parallel inhibitory mechanisms. Development (Cambridge, England). PMID 30814118 DOI: 10.1242/Dev.171116 |
0.432 |
|
| 2018 |
Folkmann AW, Seydoux G. Single-molecule study reveals the frenetic lives of proteins in gradients. Proceedings of the National Academy of Sciences of the United States of America. 115: 9336-9338. PMID 30181287 DOI: 10.1073/Pnas.1812248115 |
0.435 |
|
| 2018 |
Seydoux G. The P Granules of C. elegans: A Genetic Model for the Study of RNA-Protein Condensates. Journal of Molecular Biology. PMID 30096346 DOI: 10.1016/J.Jmb.2018.08.007 |
0.429 |
|
| 2018 |
Seydoux G. The P Granules of C. elegans: A Genetic Model for the Study of RNA-Protein Condensates. Journal of Molecular Biology. PMID 30096346 DOI: 10.1016/j.jmb.2018.08.007 |
0.318 |
|
| 2017 |
Paix A, Folkmann A, Goldman DH, Kulaga H, Grzelak MJ, Rasoloson D, Paidemarry S, Green R, Reed RR, Seydoux G. Precision genome editing using synthesis-dependent repair of Cas9-induced DNA breaks. Proceedings of the National Academy of Sciences of the United States of America. 114: E10745-E10754. PMID 29183983 DOI: 10.1073/Pnas.1711979114 |
0.305 |
|
| 2017 |
Lee CS, Lu T, Seydoux G. Nanos promotes epigenetic reprograming of the germline by down-regulation of the THAP transcription factor LIN-15B. Elife. 6. PMID 29111977 DOI: 10.7554/Elife.30201 |
0.427 |
|
| 2017 |
Mok CA, Au V, Thompson OA, Edgley ML, Gevirtzman L, Yochem J, Lowry J, Memar N, Wallenfang MR, Rasoloson D, Bowerman B, Schnabel R, Seydoux G, Moerman DG, Waterston RH. MIP-MAP: High Throughput Mapping of Caenorhabditis elegans Temperature-Sensitive Mutants via Molecular Inversion Probes. Genetics. PMID 28827289 DOI: 10.1534/Genetics.117.300179 |
0.744 |
|
| 2017 |
Paix A, Folkmann A, Seydoux G. Precision genome editing using CRISPR-Cas9 and linear repair templates in C. elegans. Methods (San Diego, Calif.). PMID 28392263 DOI: 10.1016/J.Ymeth.2017.03.023 |
0.303 |
|
| 2016 |
Smith J, Calidas D, Schmidt H, Lu T, Rasoloson D, Seydoux G. Spatial patterning of P granules by RNA-induced phase separation of the intrinsically-disordered protein MEG-3. Elife. 5. PMID 27914198 DOI: 10.7554/Elife.21337 |
0.379 |
|
| 2016 |
Smith J, Calidas D, Schmidt H, Lu T, Rasoloson D, Seydoux G. Author response: Spatial patterning of P granules by RNA-induced phase separation of the intrinsically-disordered protein MEG-3 Elife. DOI: 10.7554/Elife.21337.016 |
0.319 |
|
| 2015 |
Paix A, Folkmann A, Rasoloson D, Seydoux G. High Efficiency, Homology-Directed Genome Editing in Caenorhabditis elegans Using CRISPR-Cas9 Ribonucleoprotein Complexes. Genetics. 201: 47-54. PMID 26187122 DOI: 10.1534/Genetics.115.179382 |
0.359 |
|
| 2014 |
Wang JT, Smith J, Chen BC, Schmidt H, Rasoloson D, Paix A, Lambrus BG, Calidas D, Betzig E, Seydoux G. Regulation of RNA granule dynamics by phosphorylation of serine-rich, intrinsically disordered proteins in C. elegans. Elife. 3: e04591. PMID 25535836 DOI: 10.7554/Elife.04591 |
0.459 |
|
| 2014 |
Paix A, Wang Y, Smith HE, Lee CY, Calidas D, Lu T, Smith J, Schmidt H, Krause MW, Seydoux G. Scalable and versatile genome editing using linear DNAs with microhomology to Cas9 Sites in Caenorhabditis elegans. Genetics. 198: 1347-56. PMID 25249454 DOI: 10.1534/Genetics.114.170423 |
0.331 |
|
| 2014 |
Wang Y, Wang JT, Rasoloson D, Stitzel ML, O' Connell KF, Smith HE, Seydoux G. Identification of suppressors of mbk-2/DYRK by whole-genome sequencing. G3 (Bethesda, Md.). 4: 231-41. PMID 24347622 DOI: 10.1534/G3.113.009126 |
0.667 |
|
| 2014 |
Wang JT, Smith J, Chen B, Schmidt H, Rasoloson D, Paix A, Lambrus BG, Calidas D, Betzig E, Seydoux G. Author response: Regulation of RNA granule dynamics by phosphorylation of serine-rich, intrinsically disordered proteins in C. elegans Elife. DOI: 10.7554/Elife.04591.031 |
0.402 |
|
| 2013 |
Motegi F, Seydoux G. The PAR network: redundancy and robustness in a symmetry-breaking system. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 368: 20130010. PMID 24062581 DOI: 10.1098/Rstb.2013.0010 |
0.411 |
|
| 2013 |
Seydoux G. 'Goldilocks' suppressor screen identifies web of polarity regulators. Nature Cell Biology. 15: 9-10. PMID 23263368 DOI: 10.1038/Ncb2666 |
0.317 |
|
| 2013 |
Wang JT, Seydoux G. Germ cell specification. Advances in Experimental Medicine and Biology. 757: 17-39. PMID 22872473 DOI: 10.1007/978-1-4614-4015-4_2 |
0.463 |
|
| 2012 |
Voronina E, Paix A, Seydoux G. The P granule component PGL-1 promotes the localization and silencing activity of the PUF protein FBF-2 in germline stem cells. Development (Cambridge, England). 139: 3732-40. PMID 22991439 DOI: 10.1242/Dev.083980 |
0.423 |
|
| 2011 |
Motegi F, Zonies S, Hao Y, Cuenca AA, Griffin E, Seydoux G. Microtubules induce self-organization of polarized PAR domains in Caenorhabditis elegans zygotes. Nature Cell Biology. 13: 1361-7. PMID 21983565 DOI: 10.1038/Ncb2354 |
0.779 |
|
| 2011 |
Griffin EE, Odde DJ, Seydoux G. Regulation of the MEX-5 gradient by a spatially segregated kinase/phosphatase cycle. Cell. 146: 955-68. PMID 21925318 DOI: 10.1016/J.Cell.2011.08.012 |
0.423 |
|
| 2011 |
Voronina E, Seydoux G, Sassone-Corsi P, Nagamori I. RNA granules in germ cells. Cold Spring Harbor Perspectives in Biology. 3. PMID 21768607 DOI: 10.1101/Cshperspect.A002774 |
0.433 |
|
| 2010 |
Gallo CM, Wang JT, Motegi F, Seydoux G. Cytoplasmic partitioning of P granule components is not required to specify the germline in C. elegans. Science (New York, N.Y.). 330: 1685-9. PMID 21127218 DOI: 10.1126/Science.1193697 |
0.384 |
|
| 2010 |
Merritt C, Seydoux G. The Puf RNA-binding proteins FBF-1 and FBF-2 inhibit the expression of synaptonemal complex proteins in germline stem cells. Development (Cambridge, England). 137: 1787-98. PMID 20431119 DOI: 10.1242/Dev.050799 |
0.686 |
|
| 2010 |
Zonies S, Motegi F, Hao Y, Seydoux G. Symmetry breaking and polarization of the C. elegans zygote by the polarity protein PAR-2. Development (Cambridge, England). 137: 1669-77. PMID 20392744 DOI: 10.1242/Dev.045823 |
0.768 |
|
| 2010 |
Voronina E, Seydoux G. The C. elegans homolog of nucleoporin Nup98 is required for the integrity and function of germline P granules. Development (Cambridge, England). 137: 1441-50. PMID 20335358 DOI: 10.1242/Dev.047654 |
0.391 |
|
| 2010 |
Merritt C, Seydoux G. Transgenic solutions for the germline. Wormbook : the Online Review of C. Elegans Biology. 1-21. PMID 20169625 DOI: 10.1895/Wormbook.1.148.1 |
0.565 |
|
| 2009 |
Cheng KC, Klancer R, Singson A, Seydoux G. Regulation of MBK-2/DYRK by CDK-1 and the pseudophosphatases EGG-4 and EGG-5 during the oocyte-to-embryo transition. Cell. 139: 560-72. PMID 19879842 DOI: 10.1016/J.Cell.2009.08.047 |
0.46 |
|
| 2008 |
Nakamura A, Seydoux G. Less is more: specification of the germline by transcriptional repression. Development (Cambridge, England). 135: 3817-27. PMID 18997110 DOI: 10.1242/Dev.022434 |
0.411 |
|
| 2008 |
Merritt C, Rasoloson D, Ko D, Seydoux G. 3' UTRs are the primary regulators of gene expression in the C. elegans germline. Current Biology : Cb. 18: 1476-82. PMID 18818082 DOI: 10.1016/J.Cub.2008.08.013 |
0.681 |
|
| 2008 |
Gallo CM, Munro E, Rasoloson D, Merritt C, Seydoux G. Processing bodies and germ granules are distinct RNA granules that interact in C. elegans embryos. Developmental Biology. 323: 76-87. PMID 18692039 DOI: 10.1016/J.Ydbio.2008.07.008 |
0.64 |
|
| 2008 |
Ghosh D, Seydoux G. Inhibition of transcription by the Caenorhabditis elegans germline protein PIE-1: genetic evidence for distinct mechanisms targeting initiation and elongation. Genetics. 178: 235-43. PMID 18202370 DOI: 10.1534/Genetics.107.083212 |
0.46 |
|
| 2007 |
Lee MH, Hook B, Pan G, Kershner AM, Merritt C, Seydoux G, Thomson JA, Wickens M, Kimble J. Conserved regulation of MAP kinase expression by PUF RNA-binding proteins. Plos Genetics. 3: e233. PMID 18166083 DOI: 10.1371/Journal.Pgen.0030233 |
0.683 |
|
| 2007 |
Motegi F, Seydoux G. Revisiting the role of microtubules in C. elegans polarity. The Journal of Cell Biology. 179: 367-9. PMID 17984317 DOI: 10.1083/Jcb.200710062 |
0.409 |
|
| 2007 |
Stitzel ML, Cheng KC, Seydoux G. Regulation of MBK-2/Dyrk kinase by dynamic cortical anchoring during the oocyte-to-zygote transition. Current Biology : Cb. 17: 1545-54. PMID 17869113 DOI: 10.1016/J.Cub.2007.08.049 |
0.761 |
|
| 2007 |
Stitzel ML, Seydoux G. Regulation of the oocyte-to-zygote transition. Science (New York, N.Y.). 316: 407-8. PMID 17446393 DOI: 10.1126/Science.1138236 |
0.754 |
|
| 2006 |
Seydoux G, Braun RE. Pathway to totipotency: lessons from germ cells. Cell. 127: 891-904. PMID 17129777 DOI: 10.1016/J.Cell.2006.11.016 |
0.416 |
|
| 2006 |
Gallo CM, Seydoux G. Toti "potent" repressors. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 28: 865-7. PMID 16937341 DOI: 10.1002/Bies.20454 |
0.427 |
|
| 2006 |
D'Agostino I, Merritt C, Chen PL, Seydoux G, Subramaniam K. Translational repression restricts expression of the C. elegans Nanos homolog NOS-2 to the embryonic germline. Developmental Biology. 292: 244-52. PMID 16499902 DOI: 10.1016/J.Ydbio.2005.11.046 |
0.808 |
|
| 2006 |
Hao Y, Boyd L, Seydoux G. Stabilization of cell polarity by the C. elegans RING protein PAR-2. Developmental Cell. 10: 199-208. PMID 16459299 DOI: 10.1016/J.Devcel.2005.12.015 |
0.636 |
|
| 2006 |
Stitzel ML, Pellettieri J, Seydoux G. The C. elegans DYRK Kinase MBK-2 Marks Oocyte Proteins for Degradation in Response to Meiotic Maturation. Current Biology : Cb. 16: 56-62. PMID 16338136 DOI: 10.1016/J.Cub.2005.11.063 |
0.817 |
|
| 2004 |
Seydoux G. Surfing the actomyosin wave: polarization of the C. elegans zygote. Developmental Cell. 7: 285-6. PMID 15363402 DOI: 10.1016/J.Devcel.2004.08.016 |
0.411 |
|
| 2004 |
DeRenzo C, Seydoux G. A clean start: degradation of maternal proteins at the oocyte-to-embryo transition. Trends in Cell Biology. 14: 420-6. PMID 15308208 DOI: 10.1016/J.Tcb.2004.07.005 |
0.784 |
|
| 2003 |
Pellettieri J, Reinke V, Kim SK, Seydoux G. Coordinate activation of maternal protein degradation during the egg-to-embryo transition in C. elegans. Developmental Cell. 5: 451-62. PMID 12967564 DOI: 10.1016/S1534-5807(03)00231-4 |
0.813 |
|
| 2003 |
DeRenzo C, Reese KJ, Seydoux G. Exclusion of germ plasm proteins from somatic lineages by cullin-dependent degradation. Nature. 424: 685-9. PMID 12894212 DOI: 10.1038/Nature01887 |
0.757 |
|
| 2003 |
Cuenca AA, Schetter A, Aceto D, Kemphues K, Seydoux G. Polarization of the C. elegans zygote proceeds via distinct establishment and maintenance phases. Development (Cambridge, England). 130: 1255-65. PMID 12588843 DOI: 10.1242/Dev.00284 |
0.48 |
|
| 2003 |
Subramaniam K, Seydoux G. Dedifferentiation of primary spermatocytes into germ cell tumors in C. elegans lacking the pumilio-like protein PUF-8. Current Biology : Cb. 13: 134-9. PMID 12546787 DOI: 10.1016/S0960-9822(03)00005-8 |
0.806 |
|
| 2002 |
Pellettieri J, Seydoux G. Anterior-posterior polarity in C. elegans and Drosophila--PARallels and differences. Science (New York, N.Y.). 298: 1946-50. PMID 12471246 DOI: 10.1126/Science.1072162 |
0.785 |
|
| 2002 |
Wallenfang MR, Seydoux G. cdk-7 Is required for mRNA transcription and cell cycle progression in Caenorhabditis elegans embryos. Proceedings of the National Academy of Sciences of the United States of America. 99: 5527-32. PMID 11960010 DOI: 10.1073/Pnas.082618399 |
0.796 |
|
| 2001 |
Strome S, Powers J, Dunn M, Reese K, Malone CJ, White J, Seydoux G, Saxton W. Spindle dynamics and the role of gamma-tubulin in early Caenorhabditis elegans embryos. Molecular Biology of the Cell. 12: 1751-64. PMID 11408582 DOI: 10.1091/Mbc.12.6.1751 |
0.795 |
|
| 2001 |
Tenenhaus C, Subramaniam K, Dunn MA, Seydoux G. PIE-1 is a bifunctional protein that regulates maternal and zygotic gene expression in the embryonic germ line of Caenorhabditis elegans. Genes & Development. 15: 1031-40. PMID 11316796 DOI: 10.1101/Gad.876201 |
0.498 |
|
| 2001 |
Seydoux G, Schedl T. The germline in C. elegans: origins, proliferation, and silencing. International Review of Cytology. 203: 139-85. PMID 11131515 DOI: 10.1016/S0074-7696(01)03006-6 |
0.448 |
|
| 2000 |
Halpern M, Seydoux G. Embryo emergent: elucidating the cell biology of development. The Santa Cruz Conference on Developmental Biology 2000. Embo Reports. 1: 469-72. PMID 11263487 DOI: 10.1093/Embo-Reports/Kvd115 |
0.348 |
|
| 2000 |
Golden A, Sadler PL, Wallenfang MR, Schumacher JM, Hamill DR, Bates G, Bowerman B, Seydoux G, Shakes DC. Metaphase to anaphase (mat) transition-defective mutants in Caenorhabditis elegans. The Journal of Cell Biology. 151: 1469-82. PMID 11134076 DOI: 10.1083/Jcb.151.7.1469 |
0.793 |
|
| 2000 |
Wallenfang MR, Seydoux G. Polarization of the anterior-posterior axis of C. elegans is a microtubule-directed process. Nature. 408: 89-92. PMID 11081513 DOI: 10.1038/35040562 |
0.796 |
|
| 2000 |
Reese KJ, Dunn MA, Waddle JA, Seydoux G. Asymmetric segregation of PIE-1 in C. elegans is mediated by two complementary mechanisms that act through separate PIE-1 protein domains. Molecular Cell. 6: 445-55. PMID 10983990 DOI: 10.1016/S1097-2765(00)00043-5 |
0.824 |
|
| 1999 |
Subramaniam K, Seydoux G. nos-1 and nos-2, two genes related to Drosophila nanos, regulate primordial germ cell development and survival in Caenorhabditis elegans. Development (Cambridge, England). 126: 4861-71. PMID 10518502 |
0.342 |
|
| 1999 |
Batchelder C, Dunn MA, Choy B, Suh Y, Cassie C, Shim EY, Shin TH, Mello C, Seydoux G, Blackwell TK. Transcriptional repression by the Caenorhabditis elegans germ-line protein PIE-1. Genes & Development. 13: 202-12. PMID 9925644 DOI: 10.1101/Gad.13.2.202 |
0.426 |
|
| 1998 |
Tenenhaus C, Schubert C, Seydoux G. Genetic requirements for PIE-1 localization and inhibition of gene expression in the embryonic germ lineage of Caenorhabditis elegans. Developmental Biology. 200: 212-24. PMID 9705228 DOI: 10.1006/Dbio.1998.8940 |
0.407 |
|
| 1997 |
Seydoux G, Dunn MA. Transcriptionally repressed germ cells lack a subpopulation of phosphorylated RNA polymerase II in early embryos of Caenorhabditis elegans and Drosophila melanogaster. Development (Cambridge, England). 124: 2191-201. PMID 9187145 |
0.327 |
|
| 1996 |
Seydoux G. Mechanisms of translational control in early development. Current Opinion in Genetics & Development. 6: 555-61. PMID 8939728 DOI: 10.1016/S0959-437X(96)80083-9 |
0.382 |
|
| 1996 |
Seydoux G, Mello CC, Pettitt J, Wood WB, Priess JR, Fire A. Repression of gene expression in the embryonic germ lineage of C. elegans. Nature. 382: 713-6. PMID 8751441 DOI: 10.1038/382713A0 |
0.655 |
|
| 1995 |
Seydoux G, Fire A. Whole-mount in situ hybridization for the detection of RNA in Caenorhabditis elegans embryos. Methods in Cell Biology. 48: 323-37. PMID 8531733 DOI: 10.1016/S0091-679X(08)61394-1 |
0.609 |
|
| 1994 |
Bucher EA, Seydoux G. Gastrulation in the nematode Caenorhabditis elegans Seminars in Developmental Biology. 5: 121-130. DOI: 10.1006/Sedb.1994.1016 |
0.376 |
|
| 1993 |
Seydoux G, Savage C, Greenwald I. Isolation and characterization of mutations causing abnormal eversion of the vulva in Caenorhabditis elegans. Developmental Biology. 157: 423-36. PMID 8500652 DOI: 10.1006/Dbio.1993.1146 |
0.332 |
|
| 1991 |
DeVoti J, Seydoux G, Beach D, McLeod M. Interaction between ran1+ protein kinase and cAMP dependent protein kinase as negative regulators of fission yeast meiosis. The Embo Journal. 10: 3759-68. PMID 1657594 DOI: 10.1002/J.1460-2075.1991.Tb04945.X |
0.468 |
|
| 1990 |
Seydoux G, Schedl T, Greenwald I. Cell-cell interactions prevent a potential inductive interaction between soma and germline in C. elegans. Cell. 61: 939-51. PMID 2350786 DOI: 10.1016/0092-8674(90)90060-R |
0.356 |
|
| 1990 |
Greenwald I, Seydoux G. Analysis of gain-of-function mutations of the lin-12 gene of Caenorhabditis elegans. Nature. 346: 197-9. PMID 2164160 DOI: 10.1038/346197A0 |
0.322 |
|
| 1989 |
Seydoux G, Greenwald I. Cell autonomy of lin-12 function in a cell fate decision in C. elegans. Cell. 57: 1237-45. PMID 2736627 DOI: 10.1016/0092-8674(89)90060-3 |
0.336 |
|
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