Benjamin A. Nacev, Ph.D. - Publications

2013 Pharmacology Johns Hopkins University, Baltimore, MD 
Pharmacology, Pharmaceutical Chemistry, Biochemistry

15 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Head SA, Shi WQ, Yang EJ, Nacev BA, Hong SY, Pasunooti KK, Li RJ, Shim JS, Liu JO. Simultaneous Targeting of NPC1 and VDAC1 by Itraconazole Leads to Synergistic Inhibition of mTOR Signaling and Angiogenesis. Acs Chemical Biology. 12: 174-182. PMID 28103683 DOI: 10.1021/Acschembio.6B00849  0.92
2015 Kshitiz, Afzal J, Suhail Y, Ahn EH, Goyal R, Hubbi ME, Hussaini Q, Ellison DD, Goyal J, Nacev B, Kim DH, Lee JH, Frankel S, Gray K, Bankoti R, et al. Control of the interface between heterotypic cell populations reveals the mechanism of intercellular transfer of signaling proteins. Integrative Biology : Quantitative Biosciences From Nano to Macro. 7: 364-72. PMID 25784457 DOI: 10.1039/C4Ib00209A  0.92
2015 Pandey R, Botros MA, Nacev BA, Albig AR. Cyclosporin a disrupts notch signaling and vascular lumen maintenance. Plos One. 10: e0119279. PMID 25775018 DOI: 10.1371/Journal.Pone.0119279  0.92
2013 Zhang F, Bhat S, Gabelli SB, Chen X, Miller MS, Nacev BA, Cheng YL, Meyers DJ, Tenney K, Shim JS, Crews P, Amzel LM, Ma D, Liu JO. Pyridinylquinazolines selectively inhibit human methionine aminopeptidase-1 in cells Journal of Medicinal Chemistry. 56: 3996-4016. PMID 23634668 DOI: 10.1021/Jm400227Z  0.92
2012 Nacev BA, Grassi P, Dell A, Haslam SM, Liu JO. Abstract 2316: Itraconazole, an antifungal drug with anti-angiogenic activity, inhibits VEGFR2 trafficking, glycosylation, and signaling in endothelial cells Cancer Research. 72: 2316-2316. DOI: 10.1158/1538-7445.Am2012-2316  0.92
2011 Nacev BA, Grassi P, Dell A, Haslam SM, Liu JO. The antifungal drug itraconazole inhibits vascular endothelial growth factor receptor 2 (VEGFR2) glycosylation, trafficking, and signaling in endothelial cells. The Journal of Biological Chemistry. 286: 44045-56. PMID 22025615 DOI: 10.1074/Jbc.M111.278754  0.92
2011 Nacev BA, Liu JO. Synergistic inhibition of endothelial cell proliferation, tube formation, and sprouting by cyclosporin A and itraconazole. Plos One. 6: e24793. PMID 21969860 DOI: 10.1371/Journal.Pone.0024793  0.92
2011 Shi W, Nacev BA, Aftab BT, Head S, Rudin CM, Liu JO. Itraconazole side chain analogues: structure-activity relationship studies for inhibition of endothelial cell proliferation, vascular endothelial growth factor receptor 2 (VEGFR2) glycosylation, and hedgehog signaling. Journal of Medicinal Chemistry. 54: 7363-74. PMID 21936514 DOI: 10.1021/Jm200944B  0.92
2011 Nacev BA, Low WK, Huang Z, Su TT, Su Z, Alkuraya H, Kasuga D, Sun W, Träger M, Braun M, Fischer G, Zhang K, Liu JO. A calcineurin-independent mechanism of angiogenesis inhibition by a nonimmunosuppressive cyclosporin A analog. The Journal of Pharmacology and Experimental Therapeutics. 338: 466-75. PMID 21562139 DOI: 10.1124/Jpet.111.180851  0.92
2011 Wilson BA, Wang H, Nacev BA, Mease RC, Liu JO, Pomper MG, Isaacs WB. High-throughput screen identifies novel inhibitors of cancer biomarker α-methylacyl coenzyme A racemase (AMACR/P504S). Molecular Cancer Therapeutics. 10: 825-38. PMID 21441411 DOI: 10.1158/1535-7163.Mct-10-0902  0.92
2011 Aftab BT, Shi W, Nacev BA, Head S, Liu JO, Rudin CM. Abstract C147: Itraconazole side-chain analogs reveal a distinct structure-activity relationship for inhibition of hedgehog pathway signaling. Molecular Cancer Therapeutics. 10. DOI: 10.1158/1535-7163.Targ-11-C147  0.92
2010 Shi W, Nacev BA, Bhat S, Liu JO. Impact of Absolute Stereochemistry on the Antiangiogenic and Antifungal Activities of Itraconazole. Acs Medicinal Chemistry Letters. 1: 155-159. PMID 21892383 DOI: 10.1021/Ml1000068  0.92
2010 Shim JS, Matsui Y, Bhat S, Nacev BA, Xu J, Bhang HE, Dhara S, Han KC, Chong CR, Pomper MG, So A, Liu JO. Effect of nitroxoline on angiogenesis and growth of human bladder cancer. Journal of the National Cancer Institute. 102: 1855-73. PMID 21088277 DOI: 10.1093/Jnci/Djq457  0.92
2010 Xiao Q, Zhang F, Nacev BA, Liu JO, Pei D. Protein N-terminal processing: substrate specificity of Escherichia coli and human methionine aminopeptidases. Biochemistry. 49: 5588-99. PMID 20521764 DOI: 10.1021/Bi1005464  0.92
2009 Liu JO, Nacev BA, Xu J, Bhat S. It takes two binding sites for calcineurin and NFAT to tango. Molecular Cell. 33: 676-8. PMID 19328062 DOI: 10.1016/J.Molcel.2009.03.005  0.92
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