Ira Herskowitz - Publications

1981-2003 Biochemistry and biophysics University of California, San Francisco, San Francisco, CA 

179 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2007 Jeong H, Herskowitz I, Kroetz DL, Rine J. Function-altering SNPs in the human multidrug transporter gene ABCB1 identified using a Saccharomyces-based assay. Plos Genetics. 3: e39. PMID 17352537 DOI: 10.1371/journal.pgen.0030039  1
2007 Ishida S, Herskowitz I. Genetic analysis of cisplatin resistance in yeast and mammals Yeast as a Tool in Cancer Research. 393-408. DOI: 10.1007/978-1-4020-5963-6_15  1
2006 Badagnani I, Sorani M, Edwards RH, Brown C, Castro RA, Huang CC, Stryke D, Kawamoto M, Johns SJ, Carlson EJ, Taylor T, Chan W, De La Cruz M, Ferrin TE, Burchard EG, ... Herskowitz I, et al. PharmGKB submission update: VI. PMT submissions of genetic variations in neurotransmitter transporters (SLC6, SLC17, and SLC18) to the PharmGKB network. Pharmacological Reviews. 58: 5-6. PMID 16507879 DOI: 10.1124/pr.58.1.3  1
2006 Shu Y, Urban TJ, Leabman MK, Fujita T, Erdman AR, Lagpacan LL, Brown C, Castro RA, Huang CC, Stryke D, Kawamoto M, Johns SJ, Taylor TR, Chan W, De La Cruz M, ... ... Herskowitz I, et al. PharmGKB submission update: V. PMT submissions of genetic variation in SLC22 family transporters. Pharmacological Reviews. 58: 3-4. PMID 16507878 DOI: 10.1124/pr.58.1.2  1
2005 Jolly ER, Chin CS, Herskowitz I, Li H. Genome-wide identification of the regulatory targets of a transcription factor using biochemical characterization and computational genomic analysis. Bmc Bioinformatics. 6: 275. PMID 16297241 DOI: 10.1186/1471-2105-6-275  0.01
2005 Huang LS, Doherty HK, Herskowitz I. The Smk1p MAP kinase negatively regulates Gsc2p, a 1,3-beta-glucan synthase, during spore wall morphogenesis in Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences of the United States of America. 102: 12431-6. PMID 16116083 DOI: 10.1073/pnas.0502324102  1
2005 Shih JL, Reck-Peterson SL, Newitt R, Mooseker MS, Aebersold R, Herskowitz I. Cell polarity protein Spa2P associates with proteins involved in actin function in Saccharomyces cerevisiae. Molecular Biology of the Cell. 16: 4595-608. PMID 16030260 DOI: 10.1091/mbc.E05-02-0108  1
2004 Galgoczy DJ, Cassidy-Stone A, Llinás M, O'Rourke SM, Herskowitz I, DeRisi JL, Johnson AD. Genomic dissection of the cell-type-specification circuit in Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences of the United States of America. 101: 18069-74. PMID 15604142 DOI: 10.1073/pnas.0407611102  1
2004 Shu Y, Leabman MK, Feng B, Mangravite LM, Huang CC, Stryke D, Kawamoto M, Johns SJ, DeYoung J, Carlson E, Ferrin TE, Herskowitz I, Giacomini KM. PharmGKB update: III. Genetic variants of SLC22A1, solute carrier family 22 (organic cation transporter), member 1. Pharmacological Reviews. 56: 161. PMID 15169925 DOI: 10.1124/pr.56.2.2  1
2004 Makovets S, Herskowitz I, Blackburn EH. Anatomy and dynamics of DNA replication fork movement in yeast telomeric regions. Molecular and Cellular Biology. 24: 4019-31. PMID 15082794  0.04
2004 O'Rourke SM, Herskowitz I. Unique and redundant roles for HOG MAPK pathway components as revealed by whole-genome expression analysis. Molecular Biology of the Cell. 15: 532-42. PMID 14595107 DOI: 10.1091/mbc.E03-07-0521  1
2003 Schindler K, Benjamin KR, Martin A, Boglioli A, Herskowitz I, Winter E. The Cdk-activating kinase Cak1p promotes meiotic S phase through Ime2p. Molecular and Cellular Biology. 23: 8718-28. PMID 14612412 DOI: 10.1128/MCB.23.23.8718-8728.2003  1
2003 Kroetz DL, Pauli-Magnus C, Hodges LM, Huang CC, Kawamoto M, Johns SJ, Stryke D, Ferrin TE, DeYoung J, Taylor T, Carlson EJ, Herskowitz I, Giacomini KM, Clark AG. Sequence diversity and haplotype structure in the human ABCB1 (MDR1, multidrug resistance transporter) gene. Pharmacogenetics. 13: 481-94. PMID 12893986 DOI: 10.1097/01.fpc.0000054113.14659.b9  1
2003 Leabman MK, Huang CC, Stryke D, Johns SJ, Kawamoto M, Ferrin TE, DeYoung J, Taylor TR, De La Cruz M, Herskowitz I, Giacomini KM. PharmGKB update: I. Genetic variants of the organic cation transporter 2 (OCT2, SLC22A2). Pharmacological Reviews. 55: 399. PMID 12869664 DOI: 10.1124/pr.55.3.6  1
2003 Benjamin KR, Zhang C, Shokat KM, Herskowitz I. Control of landmark events in meiosis by the CDK Cdc28 and the meiosis-specific kinase Ime2. Genes & Development. 17: 1524-39. PMID 12783856 DOI: 10.1101/gad.1101503  0.12
2003 Osato DH, Huang CC, Kawamoto M, Johns SJ, Stryke D, Wang J, Ferrin TE, Herskowitz I, Giacomini KM. Functional characterization in yeast of genetic variants in the human equilibrative nucleoside transporter, ENT1. Pharmacogenetics. 13: 297-301. PMID 12724623 DOI: 10.1097/01.fpc.0000054083.64000.2a  1
2003 Shu Y, Leabman MK, Feng B, Mangravite LM, Huang CC, Stryke D, Kawamoto M, Johns SJ, DeYoung J, Carlson E, Ferrin TE, Herskowitz I, Giacomini KM. Evolutionary conservation predicts function of variants of the human organic cation transporter, OCT1. Proceedings of the National Academy of Sciences of the United States of America. 100: 5902-7. PMID 12719534 DOI: 10.1073/pnas.0730858100  1
2003 Leabman MK, Huang CC, DeYoung J, Carlson EJ, Taylor TR, de la Cruz M, Johns SJ, Stryke D, Kawamoto M, Urban TJ, Kroetz DL, Ferrin TE, Clark AG, Risch N, Herskowitz I, et al. Natural variation in human membrane transporter genes reveals evolutionary and functional constraints. Proceedings of the National Academy of Sciences of the United States of America. 100: 5896-901. PMID 12719533 DOI: 10.1073/pnas.0730857100  1
2003 Clyne RK, Katis VL, Jessop L, Benjamin KR, Herskowitz I, Lichten M, Nasmyth K. Polo-like kinase Cdc5 promotes chiasmata formation and cosegregation of sister centromeres at meiosis I. Nature Cell Biology. 5: 480-5. PMID 12717442 DOI: 10.1038/ncb977  1
2003 Stryke D, Huang CC, Kawamoto M, Johns SJ, Carlson EJ, Deyoung JA, Leabman MK, Herskowitz I, Giacomini KM, Ferrin TE. SNP analysis and presentation in the Pharmacogenetics of Membrane Transporters Project. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 535-47. PMID 12603056  1
2002 Banuett F, Herskowitz I. Bud morphogenesis and the actin and microtubule cytoskeletons during budding in the corn smut fungus, Ustilago maydis. Fungal Genetics and Biology : Fg & B. 37: 149-70. PMID 12409100 DOI: 10.1016/S1087-1845(02)00548-0  1
2002 Ishida S, Lee J, Thiele DJ, Herskowitz I. Uptake of the anticancer drug cisplatin mediated by the copper transporter Ctr1 in yeast and mammals. Proceedings of the National Academy of Sciences of the United States of America. 99: 14298-302. PMID 12370430 DOI: 10.1073/pnas.162491399  1
2002 Leabman MK, Huang CC, Kawamoto M, Johns SJ, Stryke D, Ferrin TE, DeYoung J, Taylor T, Clark AG, Herskowitz I, Giacomini KM. Polymorphisms in a human kidney xenobiotic transporter, OCT2, exhibit altered function. Pharmacogenetics. 12: 395-405. PMID 12142729 DOI: 10.1097/00008571-200207000-00007  1
2002 O'Rourke SM, Herskowitz I, O'Shea EK. Yeast go the whole HOG for the hyperosmotic response. Trends in Genetics : Tig. 18: 405-12. PMID 12142009 DOI: 10.1016/S0168-9525(02)02723-3  1
2002 O'Rourke SM, Herskowitz I. A third osmosensing branch in Saccharomyces cerevisiae requires the Msb2 protein and functions in parallel with the Sho1 branch. Molecular and Cellular Biology. 22: 4739-49. PMID 12052881 DOI: 10.1128/MCB.22.13.4739-4749.2002  1
2002 Herskowitz I. Regulating natural health products. Science (New York, N.Y.). 296: 46-7. PMID 11962491  1
2002 Herskowitz I, O'Shea E. The 2001 Thomas Hunt Morgan Medal. Yasuji Oshima. Genetics. 160: 367-8. PMID 11894818  1
2002 Irie K, Tadauchi T, Takizawa PA, Vale RD, Matsumoto K, Herskowitz I. The Khd1 protein, which has three KH RNA-binding motifs, is required for proper localization of ASH1 mRNA in yeast. The Embo Journal. 21: 1158-67. PMID 11867544 DOI: 10.1093/emboj/21.5.1158  1
2001 McBride HJ, Sil A, Measday V, Yu Y, Moffat J, Maxon ME, Herskowitz I, Andrews B, Stillman DJ. The protein kinase Pho85 is required for asymmetric accumulation of the Ash1 protein in Saccharomyces cerevisiae. Molecular Microbiology. 42: 345-53. PMID 11703659 DOI: 10.1046/j.1365-2958.2001.02601.x  1
2001 Schlumpberger M, Prusiner SB, Herskowitz I. Induction of distinct [URE3] yeast prion strains. Molecular and Cellular Biology. 21: 7035-46. PMID 11564886 DOI: 10.1128/MCB.21.20.7035-7046.2001  1
2001 Maxon ME, Herskowitz I. Ash1p is a site-specific DNA-binding protein that actively represses transcription. Proceedings of the National Academy of Sciences of the United States of America. 98: 1495-500. PMID 11171979 DOI: 10.1073/pnas.98.4.1495  1
2001 Tadauchi T, Matsumoto K, Herskowitz I, Irie K. Post-transcriptional regulation through the HO 3'-UTR by Mpt5, a yeast homolog of Pumilio and FBF. The Embo Journal. 20: 552-61. PMID 11157761 DOI: 10.1093/emboj/20.3.552  1
2001 Pauli-Magnus C, DeYoung J, Herskowitz I, Giacomini KM, Kroetz DL. Ethnic differences in the allele frequency of polymorphisms in the MDR1 gene Clinical Pharmacology and Therapeutics. 69: P75.  1
2000 Schlumpberger M, Wille H, Baldwin MA, Butler DA, Herskowitz I, Prusiner SB. The prion domain of yeast Ure2p induces autocatalytic formation of amyloid fibers by a recombinant fusion protein. Protein Science : a Publication of the Protein Society. 9: 440-51. PMID 10752606 DOI: 10.1110/ps.9.3.440  1
2000 O'Shea EK, Herskowitz I. The ins and outs of cell-polarity decisions. Nature Cell Biology. 2: E39-41. PMID 10707093 DOI: 10.1038/35004065  1
1999 Grether ME, Herskowitz I. Genetic and biochemical characterization of the yeast spo12 protein. Molecular Biology of the Cell. 10: 3689-703. PMID 10564265  1
1999 Stryker MP, Basbaum A, DeFranco T, Herskowitz I, Yamamoto K. Hospital merger leaves clinical science intact. Nature. 401: 842. PMID 10553895  0.12
1999 Bishop JM. Hospital merger leaves clinical science intact. Nature. 401: 842. PMID 10553894 DOI: 10.1038/44680  1
1999 Herskowitz I. The shower Current Biology : Cb. 9: R713. PMID 10531015  0.01
1999 Park HO, Sanson A, Herskowitz I. Localization of Bud2p, a GTPase-activating protein necessary for programming cell polarity in yeast to the presumptive bud site. Genes & Development. 13: 1912-7. PMID 10444589  1
1999 Sanders SL, Gentzsch M, Tanner W, Herskowitz I. O-Glycosylation of Axl2/Bud10p by Pmt4p is required for its stability, localization, and function in daughter cells. The Journal of Cell Biology. 145: 1177-88. PMID 10366591 DOI: 10.1083/jcb.145.6.1177  1
1998 Herskowitz I. Coming early to the late genes. Current Biology : Cb. 8: R827-8. PMID 9822585  1
1998 Butty AC, Pryciak PM, Huang LS, Herskowitz I, Peter M. The role of Far1p in linking the heterotrimeric G protein to polarity establishment proteins during yeast mating. Science (New York, N.Y.). 282: 1511-6. PMID 9822386  1
1998 Philips J, Herskowitz I. Identification of Kel1p, a kelch domain-containing protein involved in cell fusion and morphology in Saccharomyces cerevisiae. The Journal of Cell Biology. 143: 375-89. PMID 9786949 DOI: 10.1083/jcb.143.2.375  1
1998 Chu S, DeRisi J, Eisen M, Mulholland J, Botstein D, Brown PO, Herskowitz I. The transcriptional program of sporulation in budding yeast. Science (New York, N.Y.). 282: 699-705. PMID 9784122 DOI: 10.1126/science.282.5389.699  1
1998 O'Rourke SM, Herskowitz I. The Hog1 MAPK prevents cross talk between the HOG and pheromone response MAPK pathways in Saccharomyces cerevisiae. Genes & Development. 12: 2874-86. PMID 9744864  1
1998 Tabtiang RK, Herskowitz I. Nuclear proteins Nut1p and Nut2p cooperate to negatively regulate a Swi4p-dependent lacZ reporter gene in Saccharomyces cerevisiae. Molecular and Cellular Biology. 18: 4707-18. PMID 9671481  1
1998 Chu S, Herskowitz I. Gametogenesis in yeast is regulated by a transcriptional cascade dependent on Ndt80. Molecular Cell. 1: 685-96. PMID 9660952  1
1998 Herskowitz I, Stahl FW. Genes to Cells in Mishima. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 3: 1-8. PMID 9581977 DOI: 10.1046/j.1365-2443.1998.00165.x  1
1998 Shaham S, Shuman MA, Herskowitz I. Death-defying yeast identify novel apoptosis genes. Cell. 92: 425-7. PMID 9491882 DOI: 10.1016/S0092-8674(00)80934-4  1
1997 Herskowitz I. Building organs and organisms: elements of morphogenesis exhibited by budding yeast. Cold Spring Harbor Symposia On Quantitative Biology. 62: 57-63. PMID 9598336  1
1997 Henchoz S, Chi Y, Catarin B, Herskowitz I, Deshaies RJ, Peter M. Phosphorylation- and ubiquitin-dependent degradation of the cyclin-dependent kinase inhibitor Far1p in budding yeast. Genes & Development. 11: 3046-60. PMID 9367986  1
1997 Gray JV, Ogas JP, Kamada Y, Stone M, Levin DE, Herskowitz I. A role for the Pkc1 MAP kinase pathway of Saccharomyces cerevisiae in bud emergence and identification of a putative upstream regulator. The Embo Journal. 16: 4924-37. PMID 9305635 DOI: 10.1093/emboj/16.16.4924  1
1997 Takizawa PA, Sil A, Swedlow JR, Herskowitz I, Vale RD. Actin-dependent localization of an RNA encoding a cell-fate determinant in yeast. Nature. 389: 90-3. PMID 9288973 DOI: 10.1038/38015  1
1997 Philips J, Herskowitz I. Osmotic balance regulates cell fusion during mating in Saccharomyces cerevisiae. The Journal of Cell Biology. 138: 961-74. PMID 9281576 DOI: 10.1083/jcb.138.5.961  1
1997 Park HO, Bi E, Pringle JR, Herskowitz I. Two active states of the Ras-related Bud1/Rsr1 protein bind to different effectors to determine yeast cell polarity. Proceedings of the National Academy of Sciences of the United States of America. 94: 4463-8. PMID 9114012 DOI: 10.1073/pnas.94.9.4463  1
1996 Peter M, Neiman AM, Park HO, van Lohuizen M, Herskowitz I. Functional analysis of the interaction between the small GTP binding protein Cdc42 and the Ste20 protein kinase in yeast. The Embo Journal. 15: 7046-59. PMID 9003780  1
1996 Leberer E, Chenevert J, Leeuw T, Harcus D, Herskowitz I, Thomas DY. Genetic interactions indicate a role for Mdg1p and the SH3 domain protein Bem1p in linking the G-protein mediated yeast pheromone signalling pathway to regulators of cell polarity. Molecular & General Genetics : Mgg. 252: 608-21. PMID 8914522 DOI: 10.1007/s004380050268  1
1996 Valtz N, Herskowitz I. Pea2 protein of yeast is localized to sites of polarized growth and is required for efficient mating and bipolar budding. The Journal of Cell Biology. 135: 725-39. PMID 8909546 DOI: 10.1083/jcb.135.3.725  1
1996 Banuett F, Herskowitz I. Discrete developmental stages during teliospore formation in the corn smut fungus, Ustilago maydis. Development (Cambridge, England). 122: 2965-76. PMID 8898211  1
1996 Sanders SL, Herskowitz I. The BUD4 protein of yeast, required for axial budding, is localized to the mother/BUD neck in a cell cycle-dependent manner. The Journal of Cell Biology. 134: 413-27. PMID 8707826 DOI: 10.1083/jcb.134.2.413  1
1996 Sil A, Herskowitz I. Identification of asymmetrically localized determinant, Ash1p, required for lineage-specific transcription of the yeast HO gene. Cell. 84: 711-22. PMID 8625409 DOI: 10.1016/S0092-8674(00)81049-1  1
1995 Herskowitz I, Park HO, Sanders S, Valtz N, Peter M. Programming of cell polarity in budding yeast by endogenous and exogenous signals. Cold Spring Harbor Symposia On Quantitative Biology. 60: 717-27. PMID 8824447  1
1995 Herskowitz I. MAP kinase pathways in yeast: for mating and more. Cell. 80: 187-97. PMID 7834739 DOI: 10.1016/0092-8674(95)90402-6  1
1995 Gerber MR, Farrell A, Deshaies RJ, Herskowitz I, Morgan DO. Cdc37 is required for association of the protein kinase Cdc28 with G1 and mitotic cyclins. Proceedings of the National Academy of Sciences of the United States of America. 92: 4651-5. PMID 7753858  1
1995 Chant J, Mischke M, Mitchell E, Herskowitz I, Pringle JR. Role of Bud3p in producing the axial budding pattern of yeast. The Journal of Cell Biology. 129: 767-78. PMID 7730410  1
1995 Kruger W, Peterson CL, Sil A, Coburn C, Arents G, Moudrianakis EN, Herskowitz I. Amino acid substitutions in the structured domains of histones H3 and H4 partially relieve the requirement of the yeast SWI/SNF complex for transcription. Genes & Development. 9: 2770-9. PMID 7590252  1
1995 Valtz N, Peter M, Herskowitz I. FAR1 is required for oriented polarization of yeast cells in response to mating pheromones. The Journal of Cell Biology. 131: 863-73. PMID 7490290 DOI: 10.1083/jcb.131.4.863  1
1994 Neiman AM, Herskowitz I. Reconstitution of a yeast protein kinase cascade in vitro: activation of the yeast MEK homologue STE7 by STE11. Proceedings of the National Academy of Sciences of the United States of America. 91: 3398-402. PMID 8159759  1
1994 Kaffman A, Herskowitz I, Tjian R, O'Shea EK. Phosphorylation of the transcription factor PHO4 by a cyclin-CDK complex, PHO80-PHO85. Science (New York, N.Y.). 263: 1153-6. PMID 8108735  1
1994 Peter M, Herskowitz I. Direct inhibition of the yeast cyclin-dependent kinase Cdc28-Cln by Far1. Science (New York, N.Y.). 265: 1228-31. PMID 8066461  1
1994 Chenevert J, Valtz N, Herskowitz I. Identification of genes required for normal pheromone-induced cell polarization in Saccharomyces cerevisiae. Genetics. 136: 1287-96. PMID 8013906  1
1994 Anna-Arriola SS, Herskowitz I. Isolation and DNA sequence of the STE13 gene encoding dipeptidyl aminopeptidase. Yeast (Chichester, England). 10: 801-10. PMID 7975897 DOI: 10.1002/yea.320100610  1
1994 Espinoza FH, Ogas J, Herskowitz I, Morgan DO. Cell cycle control by a complex of the cyclin HCS26 (PCL1) and the kinase PHO85. Science (New York, N.Y.). 266: 1388-91. PMID 7973730  1
1994 Peter M, Herskowitz I. Joining the complex: cyclin-dependent kinase inhibitory proteins and the cell cycle. Cell. 79: 181-4. PMID 7954786 DOI: 10.1016/0092-8674(94)90186-4  1
1994 Banuett F, Herskowitz I. Identification of fuz7, a Ustilago maydis MEK/MAPKK homolog required for a-locus-dependent and -independent steps in the fungal life cycle. Genes & Development. 8: 1367-78. PMID 7926737  1
1994 Banuett F, Herskowitz I. Morphological transitions in the life cycle of Ustilago maydis and their genetic control by the a and b loci Experimental Mycology. 18: 247-266. DOI: 10.1006/emyc.1994.1024  1
1993 Peter M, Gartner A, Horecka J, Ammerer G, Herskowitz I. FAR1 links the signal transduction pathway to the cell cycle machinery in yeast. Cell. 73: 747-60. PMID 8500168 DOI: 10.1016/0092-8674(93)90254-N  1
1993 McElreavey K, Vilain E, Abbas N, Herskowitz I, Fellous M. A regulatory cascade hypothesis for mammalian sex determination: SRY represses a negative regulator of male development. Proceedings of the National Academy of Sciences of the United States of America. 90: 3368-72. PMID 8475082  1
1993 Neiman AM, Stevenson BJ, Xu HP, Sprague GF, Herskowitz I, Wigler M, Marcus S. Functional homology of protein kinases required for sexual differentiation in Schizosaccharomyces pombe and Saccharomyces cerevisiae suggests a conserved signal transduction module in eukaryotic organisms. Molecular Biology of the Cell. 4: 107-20. PMID 8443406  1
1993 Park HO, Chant J, Herskowitz I. BUD2 encodes a GTPase-activating protein for Bud1/Rsr1 necessary for proper bud-site selection in yeast. Nature. 365: 269-74. PMID 8371782 DOI: 10.1038/365269a0  1
1993 Li JJ, Herskowitz I. Isolation of ORC6, a component of the yeast origin recognition complex by a one-hybrid system. Science (New York, N.Y.). 262: 1870-4. PMID 8266075  1
1993 Noble JA, Innis MA, Koonin EV, Rudd KE, Banuett F, Herskowitz I. The Escherichia coli hflA locus encodes a putative GTP-binding protein and two membrane proteins, one of which contains a protease-like domain. Proceedings of the National Academy of Sciences of the United States of America. 90: 10866-70. PMID 8248183 DOI: 10.1073/pnas.90.22.10866  1
1992 Horvitz HR, Herskowitz I. Mechanisms of asymmetric cell division: two Bs or not two Bs, that is the question. Cell. 68: 237-55. PMID 1733500  1
1992 Hoffmann FM, Sternberg PW, Herskowitz I. Learning about cancer genes through invertebrate genetics. Current Opinion in Genetics & Development. 2: 45-52. PMID 1633426 DOI: 10.1016/S0959-437X(05)80320-X  1
1992 Herskowitz I. Fungal physiology. Yeast branches out. Nature. 357: 190-1. PMID 1589015 DOI: 10.1038/357190a0  1
1992 Herskowitz I. Rage and confusion hide role of HIV Nature. 357: 188-191. PMID 1589014  1
1992 Chenevert J, Corrado K, Bender A, Pringle J, Herskowitz I. A yeast gene (BEM1) necessary for cell polarization whose product contains two SH3 domains. Nature. 356: 77-9. PMID 1538785 DOI: 10.1038/356077a0  1
1992 Chang F, Herskowitz I. Phosphorylation of FAR1 in response to alpha-factor: a possible requirement for cell-cycle arrest. Molecular Biology of the Cell. 3: 445-50. PMID 1498364  1
1992 Trueheart J, Herskowitz I. The a locus governs cytoduction in Ustilago maydis. Journal of Bacteriology. 174: 7831-3. PMID 1447150  1
1992 Lee RT, Peterson CL, Calman AF, Herskowitz I, O'Donnell JJ. Cloning of a human galactokinase gene (GK2) on chromosome 15 by complementation in yeast. Proceedings of the National Academy of Sciences of the United States of America. 89: 10887-91. PMID 1438294 DOI: 10.1073/pnas.89.22.10887  1
1992 Yoshinaga SK, Peterson CL, Herskowitz I, Yamamoto KR. Roles of SWI1, SWI2, and SWI3 proteins for transcriptional enhancement by steroid receptors. Science (New York, N.Y.). 258: 1598-604. PMID 1360703  1
1992 Peterson CL, Herskowitz I. Characterization of the yeast SWI1, SWI2, and SWI3 genes, which encode a global activator of transcription. Cell. 68: 573-83. PMID 1339306 DOI: 10.1016/0092-8674(92)90192-F  1
1992 Vilain E, McElreavey K, Herskowitz I, Fellous M. Sex determination: Facts and new concepts | LA DETERMINATION DU SEXE: FAITS ET NOUVEAUX CONCEPTS Medecine/Sciences. 8: I-VII.  1
1991 Kruger W, Herskowitz I. A negative regulator of HO transcription, SIN1 (SPT2), is a nonspecific DNA-binding protein related to HMG1. Molecular and Cellular Biology. 11: 4135-46. PMID 2072912  1
1991 Chant J, Herskowitz I. Genetic control of bud site selection in yeast by a set of gene products that constitute a morphogenetic pathway. Cell. 65: 1203-12. PMID 2065354  1
1991 Herskowitz I, Jensen RE. Putting the HO gene to work: practical uses for mating-type switching. Methods in Enzymology. 194: 132-46. PMID 2005783 DOI: 10.1016/0076-6879(91)94011-Z  1
1991 Peterson CL, Kruger W, Herskowitz I. A functional interaction between the C-terminal domain of RNA polymerase II and the negative regulator SIN1. Cell. 64: 1135-43. PMID 2004420 DOI: 10.1016/0092-8674(91)90268-4  1
1991 Covitz PA, Herskowitz I, Mitchell AP. The yeast RME1 gene encodes a putative zinc finger protein that is directly repressed by a1-alpha 2. Genes & Development. 5: 1982-9. PMID 1936989  1
1991 Chant J, Corrado K, Pringle JR, Herskowitz I. Yeast BUD5, encoding a putative GDP-GTP exchange factor, is necessary for bud site selection and interacts with bud formation gene BEM1. Cell. 65: 1213-24. PMID 1905981  1
1991 Herskowitz I, Ogas J, Andrews BJ, Chang F. Regulators of synthesis and activity of the G1 cyclins of budding yeast. Cold Spring Harbor Symposia On Quantitative Biology. 56: 33-40. PMID 1840254  1
1991 Ogas J, Andrews BJ, Herskowitz I. Transcriptional activation of CLN1, CLN2, and a putative new G1 cyclin (HCS26) by SWI4, a positive regulator of G1-specific transcription. Cell. 66: 1015-26. PMID 1832336 DOI: 10.1016/0092-8674(91)90445-5  1
1991 Marsh L, Neiman AM, Herskowitz I. Signal transduction during pheromone response in yeast. Annual Review of Cell Biology. 7: 699-728. PMID 1667085 DOI: 10.1146/annurev.cb.07.110191.003411  1
1990 Brenner S, Dove W, Herskowitz I, Thomas R. Genes and development: molecular and logical themes. Genetics. 126: 479-86. PMID 2249752  1
1990 Wang H, Clark I, Nicholson PR, Herskowitz I, Stillman DJ. The Saccharomyces cerevisiae SIN3 gene, a negative regulator of HO, contains four paired amphipathic helix motifs. Molecular and Cellular Biology. 10: 5927-36. PMID 2233725  1
1990 Andrews BJ, Herskowitz I. Regulation of cell cycle-dependent gene expression in yeast. The Journal of Biological Chemistry. 265: 14057-60. PMID 2201678  1
1990 Chang F, Herskowitz I. Identification of a gene necessary for cell cycle arrest by a negative growth factor of yeast: FAR1 is an inhibitor of a G1 cyclin, CLN2. Cell. 63: 999-1011. PMID 2147873 DOI: 10.1016/0092-8674(90)90503-7  1
1990 Neiman AM, Chang F, Komachi K, Herskowitz I. CDC36 and CDC39 are negative elements in the signal transduction pathway of yeast. Cell Regulation. 1: 391-401. PMID 2099190  1
1990 Schulz B, Banuett F, Dahl M, Schlesinger R, Schäfer W, Martin T, Herskowitz I, Kahmann R. The b alleles of U. maydis, whose combinations program pathogenic development, code for polypeptides containing a homeodomain-related motif. Cell. 60: 295-306. PMID 1967554 DOI: 10.1016/0092-8674(90)90744-Y  1
1990 Neiman AM, Chang F, Komachi K, Herskowitz I. CDC36 and CDC39 are negative elements in the signal transduction pathway of yeast Molecular Biology of the Cell. 1: 391-401.  1
1989 Banuett F, Herskowitz I. Different a alleles of Ustilago maydis are necessary for maintenance of filamentous growth but not for meiosis. Proceedings of the National Academy of Sciences of the United States of America. 86: 5878-82. PMID 16594058  0.08
1989 Andrews BJ, Herskowitz I. The yeast SWI4 protein contains a motif present in developmental regulators and is part of a complex involved in cell-cycle-dependent transcription. Nature. 342: 830-3. PMID 2689885 DOI: 10.1038/342830a0  1
1989 Andrews BJ, Herskowitz I. Identification of a DNA binding factor involved in cell-cycle control of the yeast HO gene. Cell. 57: 21-9. PMID 2649246 DOI: 10.1016/0092-8674(89)90168-2  1
1989 Herskowitz I. A regulatory hierarchy for cell specialization in yeast. Nature. 342: 749-57. PMID 2513489 DOI: 10.1038/342749a0  1
1988 Michaelis S, Herskowitz I. The a-factor pheromone of Saccharomyces cerevisiae is essential for mating. Molecular and Cellular Biology. 8: 1309-18. PMID 3285180  1
1988 Marsh L, Herskowitz I. From membrane to nucleus: The pathway of signal transduction in yeast and its genetic control Cold Spring Harbor Symposia On Quantitative Biology. 53: 557-565. PMID 3151177  1
1988 Herskowitz I. Life cycle of the budding yeast Saccharomyces cerevisiae. Microbiological Reviews. 52: 536-53. PMID 3070323  1
1988 Herskowitz I. The Hawthorne deletion twenty-five years later. Genetics. 120: 857-61. PMID 3066686  1
1988 Marsh L, Herskowitz I. STE2 protein of Saccharomyces kluyveri is a member of the rhodopsin/beta-adrenergic receptor family and is responsible for recognition of the peptide ligand alpha factor. Proceedings of the National Academy of Sciences of the United States of America. 85: 3855-9. PMID 2836861  1
1987 Wilson KL, Herskowitz I. STE16, a new gene required for pheromone production by a cells of Saccharomyces cerevisiae Genetics. 115: 441-449. PMID 3552875  1
1987 Sternberg PW, Stern MJ, Clark I, Herskowitz I. Activation of the yeast HO gene by release from multiple negative controls. Cell. 48: 567-77. PMID 3545494 DOI: 10.1016/0092-8674(87)90235-2  1
1987 Rine J, Herskowitz I. Four genes responsible for a position effect on expression from HML and HMR in Saccharomyces cerevisiae Genetics. 116: 9-22. PMID 3297920  1
1987 Banuett F, Herskowitz I. Identification of polypeptides encoded by an Escherichia coli locus (hflA) that governs the lysis-lysogeny decision of bacteriophage lambda Journal of Bacteriology. 169: 4076-4085. PMID 3040675  1
1987 Herskowitz I, Marsh L. Conservation of a receptor/signal transduction system Cell. 50: 995-996. PMID 3040269  1
1987 Fields S, Herskowitz I. Regulation by the yeast mating-type locus of STE12, a gene required for cell-type-specific expression Molecular and Cellular Biology. 7: 3818-3821. PMID 2824997  1
1987 Herskowitz I. Functional inactivation of genes by dominant negative mutations Nature. 329: 219-222. PMID 2442619  1
1986 Powers S, Michaelis S, Broek D, Santa Anna S, Field J, Herskowitz I, Wigler M. RAM, a gene of yeast required for a functional modification of RAS proteins and for production of mating pheromone a-factor. Cell. 47: 413-22. PMID 3533274 DOI: 10.1016/0092-8674(86)90598-2  1
1986 Wilson KL, Herskowitz I. Sequences upstream of the STE6 gene required for its expression and regulation by the mating type locus in Saccharomyces cerevisiae Proceedings of the National Academy of Sciences of the United States of America. 83: 2536-2540. PMID 3517872  1
1986 Mitchell AP, Herskowitz I. Activation of meiosis and sporulation by repression of the RME1 product in yeast Nature. 319: 738-742. PMID 3513021 DOI: 10.1038/319738a0  1
1986 Russell DW, Jensen R, Zoller MJ, Burke J, Errede B, Smith M, Herskowitz I. Structure of the Saccharomyces cerevisiae HO gene and analysis of its upstream regulatory region. Molecular and Cellular Biology. 6: 4281-94. PMID 3025649  1
1986 Banuett F, Hoyt MA, McFarlane L, Echols H, Herskowitz I. hflB, a new Escherichia coli locus regulating lysogeny and the level of bacteriophage lambda cII protein Journal of Molecular Biology. 187: 213-224. PMID 2939254 DOI: 10.1016/0022-2836(86)90229-9  1
1985 Herskowitz I. Cell biology: Yeast as the universal cell Nature. 316: 678-679. PMID 4033767 DOI: 10.1038/316678a0  1
1985 Fields S, Herskowitz I. The yeast STE12 product is required for expression of two sets of cell-type-specific genes Cell. 42: 923-930. PMID 3931921 DOI: 10.1016/0092-8674(85)90288-0  1
1985 Herskowitz I. A master regulatory locus that determines cell specialization in yeast Harvey Lectures. 81: 67-92. PMID 3916693  1
1985 Johnson AD, Herskowitz I. A repressor (MAT alpha 2 Product) and its operator control expression of a set of cell type specific genes in yeast. Cell. 42: 237-47. PMID 3893743 DOI: 10.1016/S0092-8674(85)80119-7  1
1985 Herskowitz I. Master regulatory loci in yeast and lambda Cold Spring Harbor Symposia On Quantitative Biology. 50: 565-574. PMID 2937606  1
1984 Stern M, Jensen R, Herskowitz I. Five SWI genes are required for expression of the HO gene in yeast Journal of Molecular Biology. 178: 853-868. PMID 6436497 DOI: 10.1016/0022-2836(84)90315-2  1
1984 Jensen RE, Herskowitz I. Directionality and regulation of cassette substitution in yeast Cold Spring Harbor Symposia On Quantitative Biology. 97-104. PMID 6397325  1
1984 Hall MN, Hereford L, Herskowitz I. Targeting of E. coli β-galactosidase to the nucleus in yeast Cell. 36: 1057-1065. PMID 6323016 DOI: 10.1016/0092-8674(84)90055-2  1
1984 Friedman DI, Olson ER, Georgopoulos C, Tilly K, Herskowitz I, Banuett F. Interactions of bacteriophage and host macromolecules in the growth of bacteriophage λ Microbiological Reviews. 48: 299-325. PMID 6240590  1
1984 Wilson KL, Herskowitz I. Negative regulation of STE6 gene expression by the α2 product of Saccharomyces cerevisiae Molecular and Cellular Biology. 4: 2420-2427. PMID 6096697  1
1983 Kassir Y, Hicks JB, Herskowitz I. SAD mutation of Saccharomyces cerevisiae is an extra a cassette Molecular and Cellular Biology. 3: 871-880. PMID 6346059  1
1983 Jensen R, Sprague GF, Herskowitz I. Regulation of yeast mating-type interconversion: feedback control of HO gene expression by the mating-type locus Proceedings of the National Academy of Sciences of the United States of America. 80: 3035-3039. PMID 6344075  1
1983 Sprague GF, Jensen R, Herskowitz I. Control of yeast cell type by the mating type locus: Positive regulation of the α-specific STE3 gene by the MATα 1 product Cell. 32: 409-415. PMID 6337727 DOI: 10.1016/0092-8674(83)90460-9  1
1983 Chan CS, Tye BK. A family of Saccharomyces cerevisiae repetitive autonomously replicating sequences that have very similar genomic environments. Journal of Molecular Biology. 168: 505-23. PMID 6310122 DOI: 10.1016/S0022-2836(83)80299-X  1
1983 Herskowitz I. Cellular differentiation, cell lineages, and transposable genetic cassettes in yeast Current Topics in Developmental Biology. 18: 1-14. PMID 6301757  1
1983 Ward DF, DeLong A, Gottesman ME. Escherichia coli nusB mutations that suppress nusA1 exhibit lambda N specificity. Journal of Molecular Biology. 168: 73-85. PMID 6224023 DOI: 10.1016/S0022-2836(83)80323-4  1
1982 Kurjan J, Herskowitz I. Structure of a yeast pheromone gene (MFα): A putative α-factor precursor contains four tandem copies of mature α-factor Cell. 30: 933-943. PMID 6754095 DOI: 10.1016/0092-8674(82)90298-7  1
1982 Forbes D, Herskowitz I. Polarity suppression by the Q gene product of bacteriophage λ Journal of Molecular Biology. 160: 549-569. PMID 6217346 DOI: 10.1016/0022-2836(82)90314-X  1
1981 Rine J, Sprague GF, Herskowitz I. rme1 Mutation of Saccharomyces cerevisiae: Map position and bypass of mating type locus control of sporulation Molecular and Cellular Biology. 1: 958-960. PMID 7050660  1
1981 Sprague GF, Rine J, Herskowitz I. Control of yeast cell type by the mating type locus. II. Genetic interactions between MATα and unlinked α-specific STE genes Journal of Molecular Biology. 153: 323-335. PMID 7040682 DOI: 10.1016/0022-2836(81)90281-3  1
1981 Sprague GF, Herskowitz I. Control of yeast cell type by the mating type locus. I. Identification and control of expression of the a-specific gene BAR1 Journal of Molecular Biology. 153: 305-321. PMID 7040681 DOI: 10.1016/0022-2836(81)90280-1  1
1981 Strathern J, Hicks J, Herskowitz I. Control of cell type in yeast by the mating type locus. The α1-α2 hypothesis Journal of Molecular Biology. 147: 357-372. PMID 7031257 DOI: 10.1016/0022-2836(81)90488-5  1
1981 Rine J, Jensen R, Hagen D, Blair L, Herskowitz I. Pattern of switching and fate of the replaced cassette in yeast mating-type interconversion Cold Spring Harbor Symposia On Quantitative Biology. 45: 951-960. PMID 6266770  1
1981 Sprague GF, Rine J, Herskowitz I. Homology and non-homology at the yeast mating type locus Nature. 289: 250-252. PMID 6256657 DOI: 10.1038/289250a0  1
1980 Rine J, Herskowitz I. The trans action of HMRa in mating type interconversion Mgg Molecular & General Genetics. 180: 99-105. PMID 7003314 DOI: 10.1007/BF00267357  1
1980 Herskowitz I, Hagen D. The lysis-lysogeny decision of phage lambda: explicit programming and responsiveness Annual Review of Genetics. 14: 399-445. PMID 6452089  1
1980 Toothman P, Herskowitz I. Rex-dependent exclusion of lambdoid phages III. Physiology of the abortive infection Virology. 102: 161-171. PMID 6445123 DOI: 10.1016/0042-6822(80)90078-1  1
1980 Toothman P, Herskowitz I. Rex-dependent exclusion of lambdoid phages II. Determinants of sensitivity to exclusion Virology. 102: 147-160. PMID 6445122 DOI: 10.1016/0042-6822(80)90077-X  1
1980 Kassir Y, Herskowitz I. A dominant mutation (SAD) bypassing the requirement for the a mating type locus in yeast sporulation Mgg Molecular & General Genetics. 180: 315-322. DOI: 10.1007/BF00425843  1
1979 Rine J, Strathern JN, Hicks JB, Herskowitz I. A suppressor of mating-type locus mutations in Saccharomyces cerevisiae: Evidence for and identification of cryptic mating-type loci Genetics. 93: 877-901. PMID 397913  1
1979 Strathern JN, Newlon CS, Herskowitz I, Hicks JB. Isolation of a circular derivative of yeast chromosome III: implications for the mechanism of mating type interconversion Cell. 18: 309-319. PMID 387260 DOI: 10.1016/0092-8674(79)90050-3  1
1979 Strathern JN, Herskowitz I. Asymmetry and directionality in production of new cell types during clonal growth: the switching pattern of homothallic yeast Cell. 17: 371-381. PMID 378408 DOI: 10.1016/0092-8674(79)90163-6  1
1979 McCullough J, Herskowitz I. Mating pheromones of Saccharomyces kluyveri: Pheromone interactions between Saccharomyces kluyveri and Saccharomyces cerevisiae Journal of Bacteriology. 138: 146-154. PMID 374360  1
1979 Jones MO, Fischer R, Herskowitz I, Echols H. Location of the regulatory site for establishment of repression by bacteriophage λ Proceedings of the National Academy of Sciences of the United States of America. 76: 150-154. PMID 284327  1
1979 Kushner PJ, Blair LC, Herskowitz I. Control of yeast cell types by mobile genes: A test Proceedings of the National Academy of Sciences of the United States of America. 76: 5264-5268.  1
1979 Strathern JN, Blair LC, Herskowitz I. Healing of mat mutations and control of mating type interconversion by the mating type locus in Saccharomyces cerevisiae Proceedings of the National Academy of Sciences of the United States of America. 76: 3425-3429.  1
1978 Jones MO, Herskowitz I. Mutants of bacteriophage λ which do not require the cIII gene for efficient lysogenization Virology. 88: 199-212. PMID 695324 DOI: 10.1016/0042-6822(78)90277-5  1
1977 Hicks JB, Herskowitz I. Interconversion of yeast mating types. II. Restoration of mating ability to sterile mutants in homothallic and heterothallic strains Genetics. 85: 373-393.  1
1977 Hicks JB, Strathern JN, Herskowitz I. Interconversion of yeast mating types. III. Action of the homothallism (HO) gene in cells homozygous for the mating type locus Genetics. 85: 395-405.  1
1976 Hicks JB, Herskowitz I. Evidence for a new diffusible element of mating pheromones in yeast Nature. 260: 246-248. PMID 768777  1
1976 Hicks JB, Herskowitz I. Interconversion of yeast mating types. I. Direct observations of the action of the homothallism (HO) gene Genetics. 83: 245-258.  1
1975 Eisen H, Georgiou M, Georgopoulos CP, Selzer G, Gussin G, Herskowitz I. The role of gene cro in phage development Virology. 68: 266-269. PMID 1189294 DOI: 10.1016/0042-6822(75)90168-3  1
1975 Strathern A, Herskowitz I. Defective prophage in Escherichia coli K12 strains Virology. 67: 136-143. PMID 1101520 DOI: 10.1016/0042-6822(75)90411-0  1
1974 Botstein D, Herskowitz I. Properties of hybrids between Salmonella phage P22 and coliphage lambda. Nature. 251: 584-9. PMID 4608090 DOI: 10.1038/251584a0  1
1974 Herskowitz I, Signer ER. Substitution mutation in bacteriophage lambda with new specificity for late gene expression. Virology. 61: 112-9. PMID 4415976 DOI: 10.1016/0042-6822(74)90246-3  1
1973 Herskowitz I. Control of gene expression in bacteriophage lambda Annual Review of Genetics. 7: 289-324. PMID 4593306  1
1971 Beckwith J, Herskowitz I, Ptashne M, Signer E, Thomas R. Political discussions at Gordon Conference [4] Science. 171: 752.  1
1970 Herskowitz I, Signer ER. A site essential for expression of all late genes in bacteriophage lambda. Journal of Molecular Biology. 47: 545-56. PMID 5418171 DOI: 10.1016/0022-2836(70)90321-9  1
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