| Year |
Citation |
Score |
| 2023 |
Shin BS, Ivanov IP, Kim JR, Cao C, Kinzy TG, Dever TE. eEF2 diphthamide modification restrains spurious frameshifting to maintain translational fidelity. Nucleic Acids Research. PMID 37246715 DOI: 10.1093/nar/gkad461 |
0.377 |
|
| 2021 |
Mateyak MK, He D, Sharma P, Kinzy TG. Mutational analysis reveals potential phosphorylation sites in eukaryotic Elongation Factor 1A that are important for its activity. Febs Letters. PMID 34293820 DOI: 10.1002/1873-3468.14164 |
0.376 |
|
| 2020 |
Manzon ER, Kinzy TG. Identification of functional partners of translation Elongation Factor 3 in
Saccharomyces cerevisiae The Faseb Journal. 34: 1-1. DOI: 10.1096/fasebj.2020.34.s1.03652 |
0.363 |
|
| 2018 |
Mateyak MK, Pupek JK, Garino AE, Knapp MC, Colmer SF, Kinzy TG, Dunaway S. Demonstration of translation elongation factor 3 activity from a non-fungal species, Phytophthora infestans. Plos One. 13: e0190524. PMID 29300771 DOI: 10.1371/Journal.Pone.0190524 |
0.519 |
|
| 2017 |
Mateyak MK, Kinzy TG. Breaking the Silos of Protein Synthesis. Trends in Biochemical Sciences. PMID 28669455 DOI: 10.1016/J.Tibs.2017.06.006 |
0.455 |
|
| 2016 |
Dever TE, Kinzy TG, Pavitt GD. Mechanism and Regulation of Protein Synthesis in Saccharomyces cerevisiae. Genetics. 203: 65-107. PMID 27183566 DOI: 10.1534/Genetics.115.186221 |
0.478 |
|
| 2014 |
Perez WB, Kinzy TG. Translation elongation factor 1A mutants with altered actin bundling activity show reduced aminoacyl-tRNA binding and alter initiation via eIF2α phosphorylation Journal of Biological Chemistry. 289: 20928-20938. PMID 24936063 DOI: 10.1074/Jbc.M114.570077 |
0.498 |
|
| 2014 |
Esposito AM, Kinzy TG. In vivo [35S]-methionine incorporation. Methods in Enzymology. 536: 55-64. PMID 24423266 DOI: 10.1016/B978-0-12-420070-8.00005-2 |
0.382 |
|
| 2013 |
Sasikumar AN, Kinzy TG. Mutations in the chromodomain-like insertion of translation elongation factor 3 compromise protein synthesis through reduced ATPase activity. The Journal of Biological Chemistry. 289: 4853-60. PMID 24379402 DOI: 10.1074/Jbc.M113.536201 |
0.501 |
|
| 2013 |
Li Z, Gonzalez PA, Sasvari Z, Kinzy TG, Nagy PD. Methylation of translation elongation factor 1A by the METTL10-like See1 methyltransferase facilitates tombusvirus replication in yeast and plants. Virology. 448: 43-54. PMID 24314635 DOI: 10.1016/J.Virol.2013.09.012 |
0.403 |
|
| 2013 |
Mateyak MK, Kinzy TG. ADP-ribosylation of translation elongation factor 2 by diphtheria toxin in yeast inhibits translation and cell separation. The Journal of Biological Chemistry. 288: 24647-55. PMID 23853096 DOI: 10.1074/Jbc.M113.488783 |
0.428 |
|
| 2012 |
Sasikumar AN, Perez WB, Kinzy TG. The many roles of the eukaryotic elongation factor 1 complex Wiley Interdisciplinary Reviews: Rna. 3: 543-555. PMID 22555874 DOI: 10.1002/Wrna.1118 |
0.459 |
|
| 2011 |
Sasvari Z, Izotova L, Kinzy TG, Nagy PD. Synergistic roles of eukaryotic translation elongation factors 1Bγ and 1A in stimulation of tombusvirus minus-strand synthesis. Plos Pathogens. 7: e1002438. PMID 22194687 DOI: 10.1371/Journal.Ppat.1002438 |
0.397 |
|
| 2011 |
Visweswaraiah J, Lageix S, Castilho BA, Izotova L, Kinzy TG, Hinnebusch AG, Sattlegger E. Evidence that eukaryotic translation elongation factor 1A (eEF1A) binds the Gcn2 protein C terminus and inhibits Gcn2 activity Journal of Biological Chemistry. 286: 36568-36579. PMID 21849502 DOI: 10.1074/Jbc.M111.248898 |
0.483 |
|
| 2011 |
Holets LM, Cottita J, Jakkaraj S, Chakrasali R, Kinzy T, Georg G, Tash J. Effect of H2-Gamendazole and Other Indazole Carboxylic Acid (ICA) Analogs on Primary Rat Sertoli Cells Cytoskeletal Structure and Elongation Factor 1 Alpha (EEF1A1) Expression and Function. Biology of Reproduction. 85: 582-582. DOI: 10.1093/Biolreprod/85.S1.582 |
0.319 |
|
| 2010 |
Li Z, Pogany J, Tupman S, Esposito AM, Kinzy TG, Nagy PD. Translation elongation factor 1A facilitates the assembly of the tombusvirus replicase and stimulates minus-strand synthesis. Plos Pathogens. 6: e1001175. PMID 21079685 DOI: 10.1371/Journal.Ppat.1001175 |
0.46 |
|
| 2010 |
Esposito AM, Kinzy TG. The eukaryotic translation elongation Factor 1Bgamma has a non-guanine nucleotide exchange factor role in protein metabolism. The Journal of Biological Chemistry. 285: 37995-8004. PMID 20926387 DOI: 10.1074/Jbc.M110.160887 |
0.431 |
|
| 2010 |
Van Goietsenoven G, Hutton J, Becker JP, Lallemand B, Robert F, Lefranc F, Pirker C, Vandenbussche G, Van Antwerpen P, Evidente A, Berger W, Prévost M, Pelletier J, Kiss R, Kinzy TG, et al. Targeting of eEF1A with Amaryllidaceae isocarbostyrils as a strategy to combat melanomas. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 4575-84. PMID 20643906 DOI: 10.1096/Fj.10-162263 |
0.32 |
|
| 2010 |
Esposito AM, Mateyak M, He D, Lewis M, Sasikumar AN, Hutton J, Copeland PR, Kinzy TG. Eukaryotic polyribosome profile analysis Journal of Visualized Experiments : Jove. PMID 20567211 DOI: 10.3791/1948 |
0.442 |
|
| 2010 |
Mateyak MK, Kinzy TG. eEF1A: thinking outside the ribosome. The Journal of Biological Chemistry. 285: 21209-13. PMID 20444696 DOI: 10.1074/Jbc.R110.113795 |
0.486 |
|
| 2010 |
Fan Y, Schlierf M, Gaspar AC, Dreux C, Kpebe A, Chaney L, Mathieu A, Hitte C, Grémy O, Sarot E, Horn M, Zhao Y, Kinzy TG, Rabinow L. Drosophila translational elongation factor-1gamma is modified in response to DOA kinase activity and is essential for cellular viability. Genetics. 184: 141-54. PMID 19841092 DOI: 10.1534/Genetics.109.109553 |
0.415 |
|
| 2009 |
Dinman JD, Kinzy TG. Expanding the ribosomal universe. Structure (London, England : 1993). 17: 1547-8. PMID 20004156 DOI: 10.1016/J.Str.2009.11.003 |
0.584 |
|
| 2008 |
Kinzy TG, De Stefano LA, Esposito AM, Hurley JM, Roy R, Valentin-Acevedo AJ, Chang KH, Davila J, Defren JM, Donovan J, Irizarry-Barreto P, Soto A, Ysla RM, Copeland HL, Copeland PR. A birth-to-death view of mRNA from the RNA recognition motif perspective. Biochemistry and Molecular Biology Education : a Bimonthly Publication of the International Union of Biochemistry and Molecular Biology. 36: 1-8. PMID 21591152 DOI: 10.1002/Bmb.20149 |
0.439 |
|
| 2008 |
Pittman YR, Kandl K, Lewis M, Valente L, Kinzy TG. Coordination of eukaryotic translation elongation factor 1A (eEF1A) function in actin organization and translation elongation by the guanine nucleotide exchange factor eEF1Balpha. The Journal of Biological Chemistry. 284: 4739-47. PMID 19095653 DOI: 10.1074/Jbc.M807945200 |
0.473 |
|
| 2008 |
Bockhorn J, Balar B, He D, Seitomer E, Copeland PR, Kinzy TG. Genome-wide screen of Saccharomyces cerevisiae null allele strains identifies genes involved in selenomethionine resistance. Proceedings of the National Academy of Sciences of the United States of America. 105: 17682-7. PMID 19004804 DOI: 10.1073/Pnas.0805642105 |
0.368 |
|
| 2008 |
Ozturk SB, Kinzy TG. Guanine nucleotide exchange factor independence of the G-protein eEF1A through novel mutant forms and biochemical properties. The Journal of Biological Chemistry. 283: 23244-53. PMID 18562321 DOI: 10.1074/Jbc.M801095200 |
0.513 |
|
| 2008 |
Tash JS, Chakrasali R, Jakkaraj SR, Hughes J, Smith SK, Hornbaker K, Heckert LL, Ozturk SB, Hadden MK, Kinzy TG, Blagg BS, Georg GI. Gamendazole, an orally active indazole carboxylic acid male contraceptive agent, targets HSP90AB1 (HSP90BETA) and EEF1A1 (eEF1A), and stimulates Il1a transcription in rat Sertoli cells. Biology of Reproduction. 78: 1139-52. PMID 18218611 DOI: 10.1095/Biolreprod.107.062679 |
0.366 |
|
| 2007 |
Gromadski KB, Schümmer T, Strømgaard A, Knudsen CR, Kinzy TG, Rodnina MV. Kinetics of the interactions between yeast elongation factors 1A and 1Balpha, guanine nucleotides, and aminoacyl-tRNA. The Journal of Biological Chemistry. 282: 35629-37. PMID 17925388 DOI: 10.1074/Jbc.M707245200 |
0.425 |
|
| 2007 |
Galkin O, Bentley AA, Gupta S, Compton BA, Mazumder B, Kinzy TG, Merrick WC, Hatzoglou M, Pestova TV, Hellen CUT, Komar AA. Roles of the negatively charged N-terminal extension of Saccharomyces cerevisiae ribosomal protein S5 revealed by characterization of a yeast strain containing human ribosomal protein S5 Rna. 13: 2116-2128. PMID 17901157 DOI: 10.1261/Rna.688207 |
0.478 |
|
| 2007 |
Plant EP, Nguyen P, Russ JR, Pittman YR, Nguyen T, Quesinberry JT, Kinzy TG, Dinman JD. Differentiating between near- and non-cognate codons in Saccharomyces cerevisiae. Plos One. 2: e517. PMID 17565370 DOI: 10.1371/Journal.Pone.0000517 |
0.666 |
|
| 2007 |
Hampsey M, Kinzy TG. Synchronicity: policing multiple aspects of gene expression by Ctk1. Genes & Development. 21: 1288-91. PMID 17545464 DOI: 10.1101/Gad.1564807 |
0.444 |
|
| 2007 |
Gross SR, Kinzy TG. Improper organization of the actin cytoskeleton affects protein synthesis at initiation. Molecular and Cellular Biology. 27: 1974-89. PMID 17178834 DOI: 10.1128/Mcb.00832-06 |
0.462 |
|
| 2006 |
Anand M, Balar B, Ulloque R, Gross SR, Kinzy TG. Domain and nucleotide dependence of the interaction between Saccharomyces cerevisiae translation elongation factors 3 and 1A. The Journal of Biological Chemistry. 281: 32318-26. PMID 16954224 DOI: 10.1074/Jbc.M601899200 |
0.407 |
|
| 2006 |
Ozturk SB, Vishnu MR, Olarewaju O, Starita LM, Masison DC, Kinzy TG. Unique classes of mutations in the Saccharomyces cerevisiae G-protein translation elongation factor 1A suppress the requirement for guanine nucleotide exchange. Genetics. 174: 651-63. PMID 16951075 DOI: 10.1534/Genetics.106.059899 |
0.555 |
|
| 2006 |
Ortiz PA, Ulloque R, Kihara GK, Zheng H, Kinzy TG. Translation elongation factor 2 anticodon mimicry domain mutants affect fidelity and diphtheria toxin resistance. The Journal of Biological Chemistry. 281: 32639-48. PMID 16950777 DOI: 10.1074/Jbc.M607076200 |
0.5 |
|
| 2006 |
Andersen CB, Becker T, Blau M, Anand M, Halic M, Balar B, Mielke T, Boesen T, Pedersen JS, Spahn CM, Kinzy TG, Andersen GR, Beckmann R. Structure of eEF3 and the mechanism of transfer RNA release from the E-site. Nature. 443: 663-8. PMID 16929303 DOI: 10.1038/Nature05126 |
0.432 |
|
| 2006 |
Pittman YR, Valente L, Jeppesen MG, Andersen GR, Patel S, Kinzy TG. Mg2+ and a key lysine modulate exchange activity of eukaryotic translation elongation factor 1B alpha. The Journal of Biological Chemistry. 281: 19457-68. PMID 16675455 DOI: 10.1074/Jbc.M601076200 |
0.359 |
|
| 2006 |
Chatterjee I, Gross SR, Kinzy TG, Chen KY. Rapid depletion of mutant eukaryotic initiation factor 5A at restrictive temperature reveals connections to actin cytoskeleton and cell cycle progression. Molecular Genetics and Genomics : Mgg. 275: 264-76. PMID 16408210 DOI: 10.1007/S00438-005-0086-4 |
0.378 |
|
| 2005 |
Ortiz PA, Kinzy TG. Dominant-negative mutant phenotypes and the regulation of translation elongation factor 2 levels in yeast. Nucleic Acids Research. 33: 5740-8. PMID 16214807 DOI: 10.1093/Nar/Gki882 |
0.515 |
|
| 2005 |
Gross SR, Kinzy TG. Translation elongation factor 1A is essential for regulation of the actin cytoskeleton and cell morphology. Nature Structural & Molecular Biology. 12: 772-8. PMID 16116436 DOI: 10.1038/Nsmb979 |
0.418 |
|
| 2005 |
Magazinnik T, Anand M, Sattlegger E, Hinnebusch AG, Kinzy TG. Interplay between GCN2 and GCN4 expression, translation elongation factor 1 mutations and translational fidelity in yeast Nucleic Acids Research. 33: 4584-4592. PMID 16100380 DOI: 10.1093/Nar/Gki765 |
0.438 |
|
| 2005 |
Chuang SM, Chen L, Lambertson D, Anand M, Kinzy TG, Madura K. Proteasome-mediated degradation of cotranslationally damaged proteins involves translation elongation factor 1A. Molecular and Cellular Biology. 25: 403-13. PMID 15601860 DOI: 10.1128/Mcb.25.1.403-413.2005 |
0.471 |
|
| 2005 |
Anand M, Balar B, Gross S, Ortiz P, Ozturk S, Pittman Y, Ulloque R, Kinzy T. Eukaryotic Translation Elongation Reactome - a Curated Knowledgebase of Biological Pathways. 13. DOI: 10.3180/React_1477.1 |
0.411 |
|
| 2004 |
Olarewaju O, Ortiz PA, Chowdhury WQ, Chatterjee I, Kinzy TG. The translation elongation factor eEF1B plays a role in the oxidative stress response pathway. Rna Biology. 1: 89-94. PMID 17179749 DOI: 10.4161/Rna.1.2.1033 |
0.403 |
|
| 2004 |
Andersen CF, Anand M, Boesen T, Van LB, Kinzy TG, Andersen GR. Purification and crystallization of the yeast translation elongation factor eEF3. Acta Crystallographica. Section D, Biological Crystallography. 60: 1304-7. PMID 15213400 DOI: 10.1107/S0907444904010716 |
0.438 |
|
| 2003 |
Jan E, Kinzy TG, Sarnow P. Divergent tRNA-like element supports initiation, elongation, and termination of protein biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. 100: 15410-5. PMID 14673072 DOI: 10.1073/Pnas.2535183100 |
0.436 |
|
| 2003 |
Valente L, Kinzy TG. Yeast as a sensor of factors affecting the accuracy of protein synthesis. Cellular and Molecular Life Sciences : Cmls. 60: 2115-30. PMID 14618259 DOI: 10.1007/S00018-003-2334-2 |
0.466 |
|
| 2003 |
Jeppesen MG, Ortiz P, Shepard W, Kinzy TG, Nyborg J, Andersen GR. The Crystal Structure of the Glutathione S-Transferase-like Domain of Elongation Factor 1Bγ from Saccharomyces cerevisiae Journal of Biological Chemistry. 278: 47190-47198. PMID 12972429 DOI: 10.1074/Jbc.M306630200 |
0.427 |
|
| 2003 |
Pomerening JR, Valente L, Kinzy TG, Jacobs TW. Mutation of a conserved CDK site converts a metazoan Elongation Factor 1Bbeta subunit into a replacement for yeast eEF1Balpha. Molecular Genetics and Genomics : Mgg. 269: 776-88. PMID 12898219 DOI: 10.1007/S00438-003-0888-1 |
0.485 |
|
| 2003 |
Jørgensen R, Ortiz PA, Carr-Schmid A, Nissen P, Kinzy TG, Andersen GR. Two crystal structures demonstrate large conformational changes in the eukaryotic ribosomal translocase. Nature Structural Biology. 10: 379-85. PMID 12692531 DOI: 10.1038/Nsb923 |
0.743 |
|
| 2003 |
Anand M, Chakraburtty K, Marton MJ, Hinnebusch AG, Kinzy TG. Functional interactions between yeast translation eukaryotic elongation factor (eEF) 1A and eEF3 Journal of Biological Chemistry. 278: 6985-6991. PMID 12493761 DOI: 10.1074/Jbc.M209224200 |
0.505 |
|
| 2002 |
Kandl KA, Munshi R, Ortiz PA, Andersen GR, Kinzy TG, Adams AE. Identification of a role for actin in translational fidelity in yeast. Molecular Genetics and Genomics : Mgg. 268: 10-8. PMID 12242494 DOI: 10.1007/S00438-002-0726-X |
0.444 |
|
| 2002 |
Jørgensen R, Carr-Schmid A, Ortiz PA, Kinzy TG, Andersen GR. Purification and crystallization of the yeast elongation factor eEF2. Acta Crystallographica. Section D, Biological Crystallography. 58: 712-5. PMID 11914505 DOI: 10.1107/S0907444902003001 |
0.752 |
|
| 2002 |
Carr-Schmid A, Pfund C, Craig EA, Kinzy TG. Novel G-protein complex whose requirement is linked to the translational status of the cell Molecular and Cellular Biology. 22: 2564-2574. PMID 11909951 DOI: 10.1128/Mcb.22.8.2564-2574.2002 |
0.785 |
|
| 2001 |
Anand M, Valente L, Carr-Schmid A, Munshi R, Olarewaju O, Ortiz PA, Kinzy TG. Translation elongation factor 1 functions in the yeast Saccharomyces cerevisiae. Cold Spring Harbor Symposia On Quantitative Biology. 66: 439-48. PMID 12762046 DOI: 10.1101/Sqb.2001.66.439 |
0.766 |
|
| 2001 |
Ruiz-Echevarria MJ, Munshi R, Tomback J, Kinzy TG, Peltz SW. Characterization of a general stabilizer element that blocks deadenylation-dependent mRNA decay. The Journal of Biological Chemistry. 276: 30995-1003. PMID 11423548 DOI: 10.1074/Jbc.M010833200 |
0.362 |
|
| 2001 |
Andersen GR, Valente L, Pedersen L, Kinzy TG, Nyborg J. Crystal structures of nucleotide exchange intermediates in the eEF1A-eEF1Bα complex Nature Structural Biology. 8: 531-534. PMID 11373622 DOI: 10.1038/88598 |
0.451 |
|
| 2001 |
Munshi R, Kandl KA, Carr-Schmid A, Whitacre JL, Adams AE, Kinzy TG. Overexpression of translation elongation factor 1A affects the organization and function of the actin cytoskeleton in yeast. Genetics. 157: 1425-36. PMID 11290701 |
0.792 |
|
| 2001 |
Pedersen L, Andersen GR, Knudsen CR, Kinzy TG, Nyborg J. Crystallization of the yeast elongation factor complex eEF1A-eEF1Bα Acta Crystallographica Section D: Biological Crystallography. 57: 159-161. PMID 11134944 DOI: 10.1107/S0907444900015559 |
0.371 |
|
| 2000 |
Andersen GR, Pedersen L, Valente L, Chatterjee I, Kinzy TG, Kjeldgaard M, Nyborg J. Structural basis for nucleotide exchange and competition with tRNA in the yeast elongation factor complex eEF1A:eEF1Balpha. Molecular Cell. 6: 1261-6. PMID 11106763 DOI: 10.1016/S1097-2765(00)00122-2 |
0.475 |
|
| 2000 |
Lee JH, Cook JR, Pollack BP, Kinzy TG, Norris D, Pestka S. Hsl7p, the yeast homologue of human JBP1, is a protein methyltransferase. Biochemical and Biophysical Research Communications. 274: 105-11. PMID 10903903 DOI: 10.1006/Bbrc.2000.3049 |
0.402 |
|
| 1999 |
Carr-Schmid A, Durko N, Cavallius J, Merrick WC, Kinzy TG. Mutations in a GTP-binding motif of eukaryotic elongation factor 1A reduce both translational fidelity and the requirement for nucleotide exchange Journal of Biological Chemistry. 274: 30297-30302. PMID 10514524 DOI: 10.1074/Jbc.274.42.30297 |
0.765 |
|
| 1999 |
Carr-Schmid A, Valente L, Loik VI, Williams T, Starita LM, Kinzy TG. Mutations in elongation factor 1beta, a guanine nucleotide exchange factor, enhance translational fidelity. Molecular and Cellular Biology. 19: 5257-66. PMID 10409717 DOI: 10.1128/Mcb.19.8.5257 |
0.751 |
|
| 1999 |
Cui Y, González CI, Kinzy TG, Dinman JD, Peltz SW. Mutations in the MOF2/SUI1 gene affect both translation and nonsense- mediated mRNA decay Rna. 5: 794-804. PMID 10376878 DOI: 10.1017/S1355838299982055 |
0.656 |
|
| 1998 |
Cui Y, Dinman JD, Kinzy TG, Peltz SW. The Mof2/Sui1 protein is a general monitor of translational accuracy Molecular and Cellular Biology. 18: 1506-1516. PMID 9488467 DOI: 10.1128/Mcb.18.3.1506 |
0.652 |
|
| 1997 |
Asano K, Kinzy TG, Merrick WC, Hershey JW. Conservation and diversity of eukaryotic translation initiation factor eIF3. The Journal of Biological Chemistry. 272: 1101-9. PMID 8995409 DOI: 10.1074/Jbc.272.2.1101 |
0.401 |
|
| 1994 |
Kinzy TG, Ripmaster TL, Woolford JL. Multiple genes encode the translation elongation factor EF-1 gamma in Saccharomyces cerevisiae. Nucleic Acids Research. 22: 2703-7. PMID 8041634 DOI: 10.1093/Nar/22.13.2703 |
0.398 |
|
| 1993 |
Hannig EM, Cigan AM, Freeman BA, Kinzy TG. GCD11, a negative regulator of GCN4 expression, encodes the gamma subunit of eIF-2 in Saccharomyces cerevisiae. Molecular and Cellular Biology. 13: 506-20. PMID 8417348 DOI: 10.1128/MCB.13.1.506 |
0.353 |
|
| 1990 |
Anthony DD, Kinzy TG, Merrick WC. Affinity labeling of eukaryotic initiation factor 2 and elongation factor 1 alpha beta gamma with GTP analogs. Archives of Biochemistry and Biophysics. 281: 157-62. PMID 2383020 DOI: 10.1016/0003-9861(90)90426-Y |
0.4 |
|
| 1990 |
Merrick WC, Dever TE, Kinzy TG, Conroy SC, Cavallius J, Owens CL. Characterization of protein synthesis factors from rabbit reticulocytes Bba - Gene Structure and Expression. 1050: 235-240. PMID 2207148 DOI: 10.1016/0167-4781(90)90173-Y |
0.367 |
|
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