Year |
Citation |
Score |
2022 |
Mokkapati S, Narayan VM, Manyam GC, Lim AH, Duplisea JJ, Kokorovic A, Miest TS, Mitra AP, Plote D, Anand SS, Metcalfe MJ, Dunner K, Johnson BA, Czerniak BA, Nieminen T, ... ... McConkey DJ, et al. Lentiviral interferon: A novel method for gene therapy in bladder cancer. Molecular Therapy Oncolytics. 26: 141-157. PMID 35847448 DOI: 10.1016/j.omto.2022.06.005 |
0.366 |
|
2020 |
Hoffman-Censits J, Choi W, Bivalacqua TJ, Pierorazio P, Kates M, Lombardo K, Parini V, McConkey D, Trabulsi EJ, Hahn N, Matoso A. Small Cell Bladder Cancer Response to Second-line and Beyond Checkpoint Inhibitor Therapy: Retrospective Experience. Clinical Genitourinary Cancer. PMID 33358150 DOI: 10.1016/j.clgc.2020.10.009 |
0.3 |
|
2020 |
Chalfin* H, Harris K, Glavaris S, Gorin M, Kates M, Kearney M, Jendrisak A, Fong M, Matoso A, Johnson M, Pienta K, Hoffman-Censits J, Valera V, Apolo A, Bivalacqua T, ... ... McConkey D, et al. PD51-03 DIGITAL PATHOLOGY OF CIRCULATING TUMOR CELLS WITH MORPHOLOGIC ANALYSIS IS FEASIBLE IN LOCALIZED BLADDER CANCER The Journal of Urology. 203: e1084. DOI: 10.1097/Ju.0000000000000953.03 |
0.331 |
|
2020 |
Choi W, Fong M, Hoffman-Censits J, Rombardo K, Parimi V, Matoso A, Hahn N, Comperat E, Mcconkey D. Mp17-14 Molecular Characterization And Response To The Immunotherapy Of Small Cell Bladder Cancer The Journal of Urology. 203. DOI: 10.1097/Ju.0000000000000842.014 |
0.386 |
|
2019 |
Ligon JA, Oke TF, Choi W, Fong MH, Levin A, Rhee DS, Morris CD, Siegel N, Hsieu EH, Meyer CF, McConkey DJ, Anders RA, Pardoll DM, Llosa NJ. Abstract 4973: The immunosuppressive tumor microenvironment of metastatic osteosarcoma inhibits the cytotoxic effect of tumor-infiltrating lymphocytes Immunology. DOI: 10.1158/1538-7445.Sabcs18-4973 |
0.315 |
|
2019 |
Chalfin* H, Glavaris S, Gorin M, Kates M, Yan Fong MH, Bivalacqua T, Johnson M, Pienta K, Hahn N, McConkey D. MP05-02 CTC AND CTDNA ASSAYS REVEAL COMPLIMENTARY INFORMATION FOR METASTATIC UROTHELIAL CANCER PATIENTS Journal of Urology. 201. DOI: 10.1097/01.Ju.0000554992.99804.5E |
0.303 |
|
2018 |
White MC, Schroeder RD, Zhu K, Xiong K, McConkey DJ. HRI-mediated translational repression reduces proteotoxicity and sensitivity to bortezomib in human pancreatic cancer cells. Oncogene. PMID 29720726 DOI: 10.1038/S41388-018-0227-Y |
0.822 |
|
2018 |
Yoshida T, Sopko NA, Kates M, Liu X, Joice G, McConkey DJ, Bivalacqua TJ. Three-dimensional organoid culture reveals involvement of Wnt/β-catenin pathway in proliferation of bladder cancer cells. Oncotarget. 9: 11060-11070. PMID 29541396 DOI: 10.1016/J.Juro.2018.02.1697 |
0.357 |
|
2018 |
Wehrenberg B, Neal D, Ochoa A, Choi W, McConkey D. Abstract LB-317: Anti-invasive effects of saracatinib in preclinical models of luminal bladder cancer Tumor Biology. DOI: 10.1158/1538-7445.Am2018-Lb-317 |
0.328 |
|
2018 |
Glavaris S, Chalfin H, Fong M, Christenson E, Ahmed AK, Caruso E, Shin J, Johnson M, Dong L, Gorin M, Bivalacqua T, Pienta K, Hahn N, McConkey D. PD15-12 BLADDER CANCER CIRCULATING TUMOR CELL CONCENTRATION FLUCTUATES IN THE ABSENCE OF SYSTEMIC THERAPY OR SURGERY Journal of Urology. 199. DOI: 10.1016/J.Juro.2018.02.811 |
0.322 |
|
2018 |
Duplisea J, Mokkapati S, Metcalfe M, Dunner K, Czerniak B, Nieminen T, Heikura T, Yla-Herttuala S, Parker N, McConkey D, Dinney C. MP54-03 LENTIVIRAL INTERFERON: A NOVEL METHOD FOR GENE THERAPY IN BLADDER CANCER Journal of Urology. 199. DOI: 10.1016/J.Juro.2018.02.1694 |
0.305 |
|
2018 |
Duplisea J, Metcalfe M, Sundi D, Ferguson J, Li R, Pretzsch S, Kamat A, Navai N, Shah J, Bondaruk J, Czerniak B, Choi W, McConkey D, Black P, Dinney C. MP47-04 REFINING SELECTION CRITERIA FOR NEOADJUVANT CHEMOTHERAPY IN PATIENTS WITH MUSCLE INVASIVE BLADDER CANCER: COMBINING CLINICAL RISK FEATURES AND INTRINSIC MOLECULAR SUBTYPES Journal of Urology. 199. DOI: 10.1016/J.Juro.2018.02.1483 |
0.307 |
|
2017 |
Schroeder RD, Choi W, Hong DS, McConkey DJ. Autophagy is required for crizotinib-induced apoptosis in MET-amplified gastric cancer cells. Oncotarget. 8: 51675-51687. PMID 28881678 DOI: 10.18632/Oncotarget.18386 |
0.481 |
|
2017 |
Schroeder RD, Choi W, Hong DS, McConkey DJ. Autophagy is required for crizotinib-induced apoptosis in MET-amplified gastric cancer cells. Oncotarget. PMID 28637004 DOI: 10.18632/oncotarget.18386 |
0.379 |
|
2017 |
Seiler R, Ashab HA, Erho N, van Rhijn BW, Winters B, Douglas J, Van Kessel KE, Fransen van de Putte EE, Sommerlad M, Wang NQ, Choeurng V, Gibb EA, Palmer-Aronsten B, Lam LL, Buerki C, ... ... McConkey DJ, et al. Impact of Molecular Subtypes in Muscle-invasive Bladder Cancer on Predicting Response and Survival after Neoadjuvant Chemotherapy. European Urology. PMID 28390739 DOI: 10.1016/J.Eururo.2017.03.030 |
0.312 |
|
2017 |
Choi W, Ochoa A, McConkey DJ, Aine M, Höglund M, Kim WY, Real FX, Kiltie AE, Milsom I, Dyrskjøt L, Lerner SP. Genetic Alterations in the Molecular Subtypes of Bladder Cancer: Illustration in the Cancer Genome Atlas Dataset. European Urology. PMID 28365159 DOI: 10.1016/J.Eururo.2017.03.010 |
0.34 |
|
2017 |
Mobley A, Zhang S, Bondaruk J, Wang Y, Majewski T, Caraway NP, Huang L, Shoshan E, Velazquez-Torres G, Nitti G, Lee S, Lee JG, Fuentes-Mattei E, Willis D, Zhang L, ... ... McConkey D, et al. Aurora Kinase A is a Biomarker for Bladder Cancer Detection and Contributes to its Aggressive Behavior. Scientific Reports. 7: 40714. PMID 28102366 DOI: 10.1038/Srep40714 |
0.433 |
|
2017 |
Abbosh PH, Liu D, Choi W, El-Deiry WS, Rosenberg JE, McConkey D, Plimack ER, Allen EMV. Abstract 3979: Immune correlates of pathologic response in bladder cancer patients undergoing neoadjuvant chemotherapy Cancer Research. 77: 3979-3979. DOI: 10.1158/1538-7445.Am2017-3979 |
0.304 |
|
2017 |
Majewski T, Bondaruk J, Yao H, Lee S, Lee J, Zhang S, Choi W, Zhang L, Guo C, Dinney C, McConkey D, Baggerly K, Czerniak B. Molecular characterization of field effects and their progression to clinically evident bladder cancer Urologic Oncology: Seminars and Original Investigations. 35: 609. DOI: 10.1016/J.Urolonc.2017.06.010 |
0.31 |
|
2017 |
Ferguson J, Li R, Metcalfe M, Peng H, Rauscher F, McConkey D, Dinney C. MP98-07 LIMD2 EXPRESSION IS UPREGULATED IN BLADDER CANCER LYMPH NODE METASTASES, CORRELATES WITH THE AGGRESSIVE BASAL MOLECULAR PHENOTYPE, AND IS IMPLICATED IN BLADDER CANCER METASTASIS. Journal of Urology. 197. DOI: 10.1016/J.Juro.2017.02.3072 |
0.313 |
|
2017 |
Abbosh P, Liu D, Choid W, El-Deiry W, Rosenberg J, McConkey D, Plimack E, Van Allen E. MP88-11 IMMUNE CORRELATES OF PATHOLOGIC RESPONSE IN BLADDER CANCER PATIENTS UNDERGOING NEOADJUVANT CHEMOTHERAPY Journal of Urology. 197. DOI: 10.1016/J.Juro.2017.02.2736 |
0.304 |
|
2017 |
Yoshida T, Sharma A, Kates M, Sopko N, Liu X, Hahn N, McConkey D, Ahuja N, Bivalacqua T. MP65-20 EPIGENETIC PRIMING WITH 5-AZACITIDINE INCREASES SENSITIVITY OF BLADDER CANCER CELLS TO CHEMOTHERAPEUTIC AGENTS Journal of Urology. 197. DOI: 10.1016/J.Juro.2017.02.2014 |
0.393 |
|
2017 |
Kates M, Nirschl T, Sopko N, Matsui H, Baras A, Netto G, Hahn N, McConkey D, Drake C, Bivalacqua T. MP65-06 INTRAVESICAL BCG INDUCES CD4+ T CELL EXPANSION BUT NOT ACTIVATION IN A CLINICALLY RELEVANT IMMUNE COMPETENT MODEL OF BLADDER CANCER Journal of Urology. 197. DOI: 10.1016/J.Juro.2017.02.2000 |
0.333 |
|
2017 |
Seiler R, Ashab HAD, Erho N, Rhijn BWGv, Winters B, Douglas J, Kessel KV, Putte EEFvd, Sommerlad M, Wang Q, Choeurng V, Gibb EA, Palmer-Aronsten B, Lam LL, Buerki C, ... ... McConkey DJ, et al. Mp34-01 Molecular Subtypes Of Muscle Invasive Bladder Cancer Are Related To Benefit From Neoadjuvant Chemotherapy: Development Of A Single Sample Patient Assay The Journal of Urology. 197. DOI: 10.1016/J.Juro.2017.02.1018 |
0.311 |
|
2016 |
McConkey DJ, Choi W, Ochoa A, Dinney CPN. Intrinsic subtypes and bladder cancer metastasis. Asian Journal of Urology. 3: 260-267. PMID 29264194 DOI: 10.1016/j.ajur.2016.09.009 |
0.304 |
|
2016 |
Dadhania V, Zhang M, Zhang L, Bondaruk J, Majewski T, Siefker-Radtke A, Guo CC, Dinney C, Cogdell DE, Zhang S, Lee S, Lee JG, Weinstein JN, Baggerly K, McConkey D, et al. Meta-Analysis of the Luminal and Basal Subtypes of Bladder Cancer and the Identification of Signature Immunohistochemical Markers for Clinical Use. Ebiomedicine. PMID 27612592 DOI: 10.1016/J.Ebiom.2016.08.036 |
0.312 |
|
2016 |
Roth B, Jayaratna I, Sundi D, Cheng T, Melquist J, Choi W, Porten S, Nitti G, Navai N, Wszolek M, Guo C, Czerniak B, McConkey D, Dinney C. Employing an orthotopic model to study the role of epithelial-mesenchymal transition in bladder cancer metastasis. Oncotarget. PMID 27494900 DOI: 10.18632/Oncotarget.11009 |
0.4 |
|
2016 |
Czerniak B, Dinney C, McConkey D. Origins of Bladder Cancer. Annual Review of Pathology. 11: 149-74. PMID 26907529 DOI: 10.1146/Annurev-Pathol-012513-104703 |
0.416 |
|
2016 |
Sundi D, Choi W, Jayaratna IS, McConkey DJ, Dinney CPN. Differential expression of FOXF1 in bladder cancer metastases and association with established bladder cancer subtypes. Journal of Clinical Oncology. 34: 464-464. DOI: 10.1200/Jco.2016.34.2_Suppl.464 |
0.383 |
|
2016 |
Lee S, Bondaruk J, Lee S, Lee JG, Majewski T, Choi W, Guo C, Dinney C, Zhang L, Baggerly K, Behringer R, McConkey D, Czerniak B. Abstract 5172: Forerunner genes contribute to bladder carcinogenesis by altering the basal to luminal urothelial transition program Cancer Research. 76: 5172-5172. DOI: 10.1158/1538-7445.Am2016-5172 |
0.355 |
|
2015 |
Abbosh PH, McConkey DJ, Plimack ER. Targeting Signaling Transduction Pathways in Bladder Cancer. Current Oncology Reports. 17: 58. PMID 26472299 DOI: 10.1007/S11912-015-0477-6 |
0.303 |
|
2015 |
McConkey DJ, Choi W, Shen Y, Lee IL, Porten S, Matin SF, Kamat AM, Corn P, Millikan RE, Dinney C, Czerniak B, Siefker-Radtke AO. A Prognostic Gene Expression Signature in the Molecular Classification of Chemotherapy-naïve Urothelial Cancer is Predictive of Clinical Outcomes from Neoadjuvant Chemotherapy: A Phase 2 Trial of Dose-dense Methotrexate, Vinblastine, Doxorubicin, and Cisplatin with Bevacizumab in Urothelial Cancer. European Urology. PMID 26343003 DOI: 10.1016/J.Eururo.2015.08.034 |
0.346 |
|
2015 |
Matin SF, McConkey DJ. Bridging the Gap in Upper Tract Urothelial Carcinoma. European Urology. 68: 978-9. PMID 26298210 DOI: 10.1016/J.Eururo.2015.08.009 |
0.321 |
|
2015 |
Plimack ER, Dunbrack RL, Brennan TA, Andrake MD, Zhou Y, Serebriiskii IG, Slifker M, Alpaugh K, Dulaimi E, Palma N, Hoffman-Censits J, Bilusic M, Wong YN, Kutikov A, Viterbo R, ... ... McConkey DJ, et al. Defects in DNA Repair Genes Predict Response to Neoadjuvant Cisplatin-based chemotherapy in Muscle-invasive Bladder Cancer. European Urology. PMID 26238431 DOI: 10.1016/J.Eururo.2015.07.009 |
0.302 |
|
2015 |
McConkey DJ, Choi W, Dinney CP. Genetic subtypes of invasive bladder cancer. Current Opinion in Urology. 25: 449-58. PMID 26218634 DOI: 10.1097/Mou.0000000000000200 |
0.312 |
|
2015 |
McConkey DJ, Choi W, Ochoa A, Siefker-Radtke A, Czerniak B, Dinney CP. Therapeutic opportunities in the intrinsic subtypes of muscle-invasive bladder cancer. Hematology/Oncology Clinics of North America. 29: 377-94, x-xi. PMID 25836941 DOI: 10.1016/J.Hoc.2014.11.003 |
0.369 |
|
2015 |
McConkey D, Choi W, Dinney C. Reply to Mattias Aine, Fredrik Liedberg, Gottfrid Sjödahl, and Mattias Höglund's Letter to the Editor re: David J. McConkey, Woonyoung Choi, Colin P.N. Dinney. New insights into subtypes of invasive bladder cancer: considerations of the clinician. Eur Urol 2014;66:609-10. European Urology. 67: e76-8. PMID 25199718 DOI: 10.1016/J.Eururo.2014.08.064 |
0.357 |
|
2015 |
Kardos J, Melquist JJ, Chism DD, Choi W, Cockerill K, Paluri RK, Moses KA, Sonpavde G, McConkey DJ, Kim WY, Dinney CPN, Milowsky MI. Evaluation of basal and luminal subtypes of urothelial carcinoma in African American and non-African American patients. Journal of Clinical Oncology. 33: 305-305. DOI: 10.1200/Jco.2015.33.7_Suppl.305 |
0.327 |
|
2015 |
Siefker-Radtke AO, Choi W, Porten S, Shen Y, Kamat AM, Matin SF, Millikan RE, Dinney CPN, Czerniak B, McConkey DJ. The basal subtype to predict clinical benefit from neoadjuvant chemotherapy: Final results from a phase II clinical trial of DDMVAC + bevacizumab. Journal of Clinical Oncology. 33: 4531-4531. DOI: 10.1200/Jco.2015.33.7_Suppl.291 |
0.337 |
|
2015 |
Seiler R, Choi W, Lam LL, Erho N, Buerki C, Davicioni E, Thalmann GN, McConkey DJ, Black PC. Association of p53-ness with chemo-resistance in urothelial cancers treated with neoadjuvant gemcitabine plus cisplatin. Journal of Clinical Oncology. 33: 4512-4512. DOI: 10.1200/Jco.2015.33.15_Suppl.4512 |
0.369 |
|
2015 |
Ochoa AE, Zhang J, Choi W, Malouf GG, Thompson EJ, Weinstein JN, Tannir NM, Dinney C, McConkey DJ, Su X. Abstract A1-68: The long noncoding RNA SNHG18 promotes PPARγ function and luminal gene expression in muscle-invasive bladder cancer Cancer Research. 75. DOI: 10.1158/1538-7445.Transcagen-A1-68 |
0.329 |
|
2015 |
Dadhania V, Guo CG, Majewski T, Zhang L, Bondaruk J, Zhang S, Choi W, McConkey D, Dinney C, Baggerly K, Czerniak BA. Abstract 4809: Validation of molecular subtypes of urothelial carcinoma of bladder in multi-institutional and public cohorts Cancer Research. 75: 4809-4809. DOI: 10.1158/1538-7445.Am2015-4809 |
0.364 |
|
2015 |
Schroeder RD, Hong D, McConkey DJ. Abstract 4427: Apoptosis, autophagy and ATP: The dynamic interaction of cellular ATP and drug resistance in MET amplified gastric cancer Cancer Research. 75: 4427-4427. DOI: 10.1158/1538-7445.Am2015-4427 |
0.482 |
|
2015 |
Jayaratna I, Porten S, Roth B, Cheng T, Melquist J, Choi W, Pretzsch S, Bondaruk J, Guo C, Czerniak B, McConkey D, Dinney C. PI-06 TCF21, A NOVEL METASTASIS SUPPRESSOR, PROMOTES THE ACQUISITION OF A LUMINAL PHENOTYPE IN HUMAN BLADDER CANCER Journal of Urology. 193. DOI: 10.1016/J.Juro.2015.02.2905 |
0.36 |
|
2015 |
Ochoa A, Zhang J, Choi W, Malouf G, Thompson E, Weinstein J, Tannir N, Dinney C, McConkey D, Su X. MP72-06 THE LONG NON-CODING RNA SNHG18 PROMOTES PPARγ FUNCTION AND “LUMINAL” GENE EXPRESSION IN MUSCLE-INVASIVE BLADDER CANCER Journal of Urology. 193. DOI: 10.1016/J.Juro.2015.02.2640 |
0.315 |
|
2014 |
Dinney CP, Hansel D, McConkey D, Shipley W, Hagan M, Dreicer R, Lerner S, Czerniak B, Waldman F, Groshen S, True LD, Petricoin E, Theodorescu D, Hruszkewycz A, Bajorin D. Novel neoadjuvant therapy paradigms for bladder cancer: results from the National Cancer Center Institute Forum. Urologic Oncology. 32: 1108-15. PMID 25443274 DOI: 10.1016/J.Urolonc.2013.10.021 |
0.314 |
|
2014 |
Choi W, Czerniak B, Ochoa A, Su X, Siefker-Radtke A, Dinney C, McConkey DJ. Intrinsic basal and luminal subtypes of muscle-invasive bladder cancer. Nature Reviews. Urology. 11: 400-10. PMID 24960601 DOI: 10.1038/Nrurol.2014.129 |
0.392 |
|
2014 |
McConkey DJ, Choi W, Dinney CP. New insights into subtypes of invasive bladder cancer: considerations of the clinician. European Urology. 66: 609-10. PMID 24877661 DOI: 10.1016/J.Eururo.2014.05.006 |
0.391 |
|
2014 |
Choi W, Porten S, Kim S, Willis D, Plimack ER, Hoffman-Censits J, Roth B, Cheng T, Tran M, Lee IL, Melquist J, Bondaruk J, Majewski T, Zhang S, Pretzsch S, ... ... McConkey DJ, et al. Identification of distinct basal and luminal subtypes of muscle-invasive bladder cancer with different sensitivities to frontline chemotherapy. Cancer Cell. 25: 152-65. PMID 24525232 DOI: 10.1016/J.Ccr.2014.01.009 |
0.387 |
|
2014 |
Weinstein JN, Akbani R, Broom BM, Wang W, Verhaak RGW, McConkey D, Lerner S, Morgan M, Creighton CJ, Smith C, Cherniack AD, Kim J, Pedamallu CS, Noble MS, Al-Ahmadie HA, et al. Comprehensive molecular characterization of urothelial bladder carcinoma Nature. 507: 315-322. PMID 24476821 DOI: 10.1038/Nature12965 |
0.346 |
|
2014 |
Siefker-Radtke AO, Choi W, Melquist J, Shen Y, Kamat A, Matin S, Millikan R, Dinney CP, Czernial BA, McConkey DJ. Abstract CT241: Gene expression profiling in the context of neoadjuvant chemotherapy with DDMVAC+B (dose dense methotrexate, vinblastine, doxorubicin, cisplatin, and bevacizumab) can predict clinical outcomes and tumor biology Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Ct241 |
0.349 |
|
2014 |
Czerniak BA, Lee S, Bondaruk J, Lee S, Majewski T, Zhang S, Shen L, Liu Y, Guo C, Dinney C, Grossman HB, Zhang W, Bar-Eli M, Baggerly K, Behringer R, ... McConkey D, et al. Abstract 5256: Mechanism of field cancerization Cancer Research. 74: 5256-5256. DOI: 10.1158/1538-7445.Am2014-5256 |
0.372 |
|
2014 |
Roth B, Cheng T, Choi W, Dinney CP, McConkey DJ. MP21-12 WITHDRAWN: A PPARGAMMA-CHOP TRANSCRIPTIONAL NETWORK CONTROLS DIFFERENTIAL EGFR VERSUS FGFR3 DEPENDENCY IN HUMAN BLADDER CANCER CELLS. Journal of Urology. 191. DOI: 10.1016/J.Juro.2014.02.840 |
0.44 |
|
2014 |
Porten S, Roth B, Melquist J, Choi W, Pretzsch S, Bondaruk J, Guo C, Czerniak B, McConkey D, Dinney C. MP61-19 A NOVEL ROLE OF THE TRANSCRIPTION FACTOR TCF21 AS A SUPPRESSOR OF BLADDER CANCER METASTASIS Journal of Urology. 191. DOI: 10.1016/J.Juro.2014.02.1896 |
0.331 |
|
2014 |
Choi W, Porten S, Kim S, Roth B, Chang T, Willis D, Tran M, Lee I, Melquist J, Bondaruk J, Majewski T, Zhang S, Pretzsch S, Baggerly K, Plimack E, ... ... McConkey D, et al. MP61-07 IDENTIFICATION OF DISTINCT BASAL AND LUMINAL SUBSETS OF HUMAN BLADDER CANCERS WITH DIFFERENT SENSITIVITIES TO FRONTLINE CHEMOTHERAPY Journal of Urology. 191. DOI: 10.1016/J.Juro.2014.02.1884 |
0.361 |
|
2013 |
Gerald J, Laing N, Choi W, McConkey DJ, Kamat AM. Augmentation of urothelial cancer cells' response to gemcitabine and cisplatin by a Smac mimetic. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 31: 261. PMID 28136864 DOI: 10.1200/Jco.2013.31.6_Suppl.261 |
0.376 |
|
2013 |
Qi W, White MC, Choi W, Guo C, Dinney C, McConkey DJ, Siefker-Radtke A. Inhibition of inducible heat shock protein-70 (hsp72) enhances bortezomib-induced cell death in human bladder cancer cells. Plos One. 8: e69509. PMID 23874968 DOI: 10.1371/Journal.Pone.0069509 |
0.482 |
|
2013 |
Lee EK, Jinesh G G, Laing NM, Choi W, McConkey DJ, Kamat AM. A Smac mimetic augments the response of urothelial cancer cells to gemcitabine and cisplatin. Cancer Biology & Therapy. 14: 812-22. PMID 23792592 DOI: 10.4161/Cbt.25326 |
0.453 |
|
2013 |
Gust KM, McConkey DJ, Awrey S, Hegarty PK, Qing J, Bondaruk J, Ashkenazi A, Czerniak B, Dinney CP, Black PC. Fibroblast growth factor receptor 3 is a rational therapeutic target in bladder cancer. Molecular Cancer Therapeutics. 12: 1245-54. PMID 23657946 DOI: 10.1158/1535-7163.Mct-12-1150 |
0.441 |
|
2013 |
Jäger W, Horiguchi Y, Shah J, Hayashi T, Awrey S, Gust KM, Hadaschik BA, Matsui Y, Anderson S, Bell RH, Ettinger S, So AI, Gleave ME, Lee IL, Dinney CP, ... ... McConkey DJ, et al. Hiding in plain view: genetic profiling reveals decades old cross contamination of bladder cancer cell line KU7 with HeLa. The Journal of Urology. 190: 1404-9. PMID 23500642 DOI: 10.1016/J.Juro.2013.03.009 |
0.362 |
|
2013 |
Cheng T, Roth B, Choi W, Black PC, Dinney C, McConkey DJ. Fibroblast growth factor receptors-1 and -3 play distinct roles in the regulation of bladder cancer growth and metastasis: implications for therapeutic targeting. Plos One. 8: e57284. PMID 23468956 DOI: 10.1371/Journal.Pone.0057284 |
0.479 |
|
2013 |
Dinney CP, Choi W, Porten SP, Roth B, Cheng T, Willis DL, Tran MN, Lee IC, Bondaruk JE, Majewski T, Zhang S, Pretzsch SM, Baggerly KA, Siefker-Radtke AO, Czerniak B, ... McConkey DJ, et al. A STAT3- and p63-dependent transcriptional network to define a lethal basal subset of human bladder cancers. Journal of Clinical Oncology. 31: 4538-4538. DOI: 10.1200/Jco.2013.31.15_Suppl.4538 |
0.451 |
|
2013 |
Czerniak BA, Lee S, Wang Y, Bondaruk J, Majewski T, Choi W, McConkey D, Behringer RR. Abstract 307: Germline ablation of candidate forerunner gene, P2RY5, in a mouse model. Cancer Research. 73: 307-307. DOI: 10.1158/1538-7445.Am2013-307 |
0.365 |
|
2013 |
Maxwell DS, Sun D, Peng Z, Qi W, McConkey D, Abbruzzese JL, Bornmann WG. Abstract B101: Design and optimization of a new series of HSP70 inhibitors for use in the treatment of pancreatic cancer. Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Targ-13-B101 |
0.366 |
|
2012 |
McConkey DJ, White M, Yan W. HDAC inhibitor modulation of proteotoxicity as a therapeutic approach in cancer. Advances in Cancer Research. 116: 131-63. PMID 23088870 DOI: 10.1016/B978-0-12-394387-3.00004-5 |
0.412 |
|
2012 |
Braeuer RR, Zigler M, Kamiya T, Dobroff AS, Huang L, Choi W, McConkey DJ, Shoshan E, Mobley AK, Song R, Raz A, Bar-Eli M. Galectin-3 contributes to melanoma growth and metastasis via regulation of NFAT1 and autotaxin Cancer Research. 72: 5757-5766. PMID 22986745 DOI: 10.1158/0008-5472.Can-12-2424 |
0.392 |
|
2012 |
Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, ... ... McConkey DJ, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 8: 445-544. PMID 22966490 DOI: 10.4161/Auto.19496 |
0.583 |
|
2012 |
Dickstein RJ, Nitti G, Dinney CP, Davies BR, Kamat AM, McConkey DJ. Autophagy limits the cytotoxic effects of the AKT inhibitor AZ7328 in human bladder cancer cells. Cancer Biology & Therapy. 13: 1325-38. PMID 22895070 DOI: 10.4161/Cbt.21793 |
0.432 |
|
2012 |
Marquis L, Tran M, Choi W, Lee IL, Huszar D, Siefker-Radtke A, Dinney C, McConkey DJ. p63 expression correlates with sensitivity to the Eg5 inhibitor ZD4877 in bladder cancer cells. Cancer Biology & Therapy. 13: 477-86. PMID 22361733 DOI: 10.4161/Cbt.19590 |
0.497 |
|
2012 |
Choi W, Shah JB, Tran M, Svatek R, Marquis L, Lee IL, Yu D, Adam L, Wen S, Shen Y, Dinney C, McConkey DJ, Siefker-Radtke A. p63 expression defines a lethal subset of muscle-invasive bladder cancers. Plos One. 7: e30206. PMID 22253920 DOI: 10.1371/Journal.Pone.0030206 |
0.311 |
|
2012 |
Liu H, Zhang T, Chen R, McConkey DJ, Ward JF, Curley SA. Multiple kinase pathways involved in the different de novo sensitivity of pancreatic cancer cell lines to 17-AAG. The Journal of Surgical Research. 176: 147-53. PMID 22099584 DOI: 10.1016/J.Jss.2011.09.017 |
0.457 |
|
2012 |
Millward M, Price T, Townsend A, Sweeney C, Spencer A, Sukumaran S, Longenecker A, Lee L, Lay A, Sharma G, Gemmill RM, Drabkin HA, Lloyd GK, Neuteboom ST, McConkey DJ, et al. Phase 1 clinical trial of the novel proteasome inhibitor marizomib with the histone deacetylase inhibitor vorinostat in patients with melanoma, pancreatic and lung cancer based on in vitro assessments of the combination. Investigational New Drugs. 30: 2303-17. PMID 22080430 DOI: 10.1007/S10637-011-9766-6 |
0.381 |
|
2012 |
Kim MP, Truty MJ, Choi W, Kang Y, Chopin-Lally X, Gallick GE, Wang H, McConkey DJ, Hwang R, Logsdon C, Abbruzzesse J, Fleming JB. Molecular profiling of direct xenograft tumors established from human pancreatic adenocarcinoma after neoadjuvant therapy. Annals of Surgical Oncology. 19: S395-403. PMID 21701930 DOI: 10.1245/S10434-011-1839-4 |
0.391 |
|
2012 |
Cheng T, Roth B, McConkey DJ. Abstract 4578: Identification of a gene expression signature that is associated with dependency on FGFR3 rather than EGFR in bladder cancer cells Cancer Research. 72: 4578-4578. DOI: 10.1158/1538-7445.Am2012-4578 |
0.488 |
|
2012 |
Freitas GS, das A, White M, McConkey D. Abstract 4098: COX-2 expression in human pancreatic cancer cells is associated with an epithelial phenotype Cancer Research. 72: 4098-4098. DOI: 10.1158/1538-7445.Am2012-4098 |
0.47 |
|
2011 |
Ni Chonghaile T, Sarosiek KA, Vo TT, Ryan JA, Tammareddi A, Moore Vdel G, Deng J, Anderson KC, Richardson P, Tai YT, Mitsiades CS, Matulonis UA, Drapkin R, Stone R, Deangelo DJ, ... McConkey DJ, et al. Pretreatment mitochondrial priming correlates with clinical response to cytotoxic chemotherapy. Science (New York, N.Y.). 334: 1129-33. PMID 22033517 DOI: 10.1126/Science.1206727 |
0.432 |
|
2011 |
McConkey DJ. RAIDDing ER stress for oncolytic viral therapy. Cancer Cell. 20: 416-8. PMID 22014566 DOI: 10.1016/J.Ccr.2011.10.002 |
0.418 |
|
2011 |
Santos FP, Kantarjian H, McConkey D, O'Brien S, Faderl S, Borthakur G, Ferrajoli A, Wright J, Cortes J. Pilot study of bortezomib for patients with imatinib-refractory chronic myeloid leukemia in chronic or accelerated phase. Clinical Lymphoma, Myeloma & Leukemia. 11: 355-60. PMID 21816374 DOI: 10.1016/J.Clml.2011.06.004 |
0.465 |
|
2011 |
Kim MP, Fleming JB, Wang H, Abbruzzese JL, Choi W, Kopetz S, McConkey DJ, Evans DB, Gallick GE. ALDH activity selectively defines an enhanced tumor-initiating cell population relative to CD133 expression in human pancreatic adenocarcinoma. Plos One. 6: e20636. PMID 21695188 DOI: 10.1371/Journal.Pone.0020636 |
0.408 |
|
2011 |
Janku F, McConkey DJ, Hong DS, Kurzrock R. Autophagy as a target for anticancer therapy Nature Reviews Clinical Oncology. 8: 528-539. PMID 21587219 DOI: 10.1038/Nrclinonc.2011.71 |
0.421 |
|
2011 |
Chiong E, Lee IL, Dadbin A, Sabichi AL, Harris L, Urbauer D, McConkey DJ, Dickstein RJ, Cheng T, Grossman HB. Effects of mTOR inhibitor everolimus (RAD001) on bladder cancer cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 2863-73. PMID 21415218 DOI: 10.1158/1078-0432.Ccr-09-3202 |
0.467 |
|
2011 |
Shah JB, McConkey DJ, Dinney CP. New strategies in muscle-invasive bladder cancer: on the road to personalized medicine. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 2608-12. PMID 21415213 DOI: 10.1158/1078-0432.Ccr-10-2770 |
0.331 |
|
2011 |
Potts BC, Albitar MX, Anderson KC, Baritaki S, Berkers C, Bonavida B, Chandra J, Chauhan D, Cusack JC, Fenical W, Ghobrial IM, Groll M, Jensen PR, Lam KS, Lloyd GK, ... ... McConkey DJ, et al. Marizomib, a proteasome inhibitor for all seasons: preclinical profile and a framework for clinical trials. Current Cancer Drug Targets. 11: 254-84. PMID 21247382 DOI: 10.2174/156800911794519716 |
0.42 |
|
2011 |
Black PC, Brown GA, Dinney CP, Kassouf W, Inamoto T, Arora A, Gallagher D, Munsell MF, Bar-Eli M, McConkey DJ, Adam L. Receptor heterodimerization: a new mechanism for platelet-derived growth factor induced resistance to anti-epidermal growth factor receptor therapy for bladder cancer. The Journal of Urology. 185: 693-700. PMID 21168861 DOI: 10.1016/J.Juro.2010.09.082 |
0.347 |
|
2011 |
Lopez G, Torres K, Liu J, Hernandez B, Young E, Belousov R, Bolshakov S, Lazar AJ, Slopis JM, McCutcheon IE, McConkey D, Lev D. Autophagic survival in resistance to histone deacetylase inhibitors: novel strategies to treat malignant peripheral nerve sheath tumors. Cancer Research. 71: 185-96. PMID 21084276 DOI: 10.1158/0008-5472.Can-10-2799 |
0.474 |
|
2011 |
Czerniak B, Majewski T, Chung W, Limei H, Cogdell D, Bondaruk J, Zhang S, Lee S, Lee S, Shen L, Wei C, Yoo SY, Choi W, McConkey D, Weinstein J, et al. Abstract 4837: Integrated genome sequence, epigenome, and transcriptome map of bladder cancer development Cancer Research. 71: 4837-4837. DOI: 10.1158/1538-7445.Am2011-4837 |
0.339 |
|
2011 |
Gust KM, McConkey DJ, Hegarty PK, Bondaruk JE, Czerniak BA, Dinney CP, Black PC. Abstract 234: Fibroblast growth factor receptor (FGFR)-3 as a suitable target in bladder cancer Cancer Research. 71: 234-234. DOI: 10.1158/1538-7445.Am2011-234 |
0.447 |
|
2011 |
Gust KM, McConkey DJ, Hegarty PK, Bondaruk JE, Czerniak BA, Dinney CP, Black PC. 1363 TARGETING FIBROBLAST GROWTH FACTOR RECEPTOR (FGFR)-3 IN BLADDER CANCER: PRE-CLINICAL PROOF OF PRINCIPLE Journal of Urology. 185. DOI: 10.1016/J.Juro.2011.02.1185 |
0.331 |
|
2010 |
Tran MN, Goodwin Jinesh G, McConkey DJ, Kamat AM. Bladder cancer stem cells. Current Stem Cell Research & Therapy. 5: 387-95. PMID 20955163 DOI: 10.2174/157488810793351640 |
0.399 |
|
2010 |
Metwalli AR, Khanbolooki S, Jinesh G, Sundi D, Shah JB, Shrader M, Choi W, Lashinger LM, Chunduru S, McConkey DJ, McKinlay M, Kamat AM. Smac mimetic reverses resistance to TRAIL and chemotherapy in human urothelial cancer cells. Cancer Biology & Therapy. 10: 885-92. PMID 20814238 DOI: 10.4161/Cbt.10.9.13237 |
0.803 |
|
2010 |
McConkey D. Proteasome and HDAC: who's zooming who? Blood. 116: 308-9. PMID 20651078 DOI: 10.1182/Blood-2010-04-278507 |
0.419 |
|
2010 |
McConkey DJ, Lee S, Choi W, Tran M, Majewski T, Lee S, Siefker-Radtke A, Dinney C, Czerniak B. Molecular genetics of bladder cancer: Emerging mechanisms of tumor initiation and progression. Urologic Oncology. 28: 429-40. PMID 20610280 DOI: 10.1016/J.Urolonc.2010.04.008 |
0.388 |
|
2010 |
Svatek RS, Shah JB, Xing J, Chang D, Lin J, McConkey DJ, Wu X, Dinney CP. A multiplexed, particle-based flow cytometric assay identified plasma matrix metalloproteinase-7 to be associated with cancer-related death among patients with bladder cancer. Cancer. 116: 4513-9. PMID 20572047 DOI: 10.1002/Cncr.25401 |
0.301 |
|
2010 |
Zhu K, Dunner K, McConkey DJ. Proteasome inhibitors activate autophagy as a cytoprotective response in human prostate cancer cells. Oncogene. 29: 451-62. PMID 19881538 DOI: 10.1038/Onc.2009.343 |
0.822 |
|
2010 |
Chen M, Lerner S, McConkey D, Gu J, Kamat A, Grossman HB, Dinney CP, Wu X. Abstract 894: Genetic variations in the angiogenesis pathway modulate clinical outcomes of bladder cancer Cancer Research. 70: 894-894. DOI: 10.1158/1538-7445.Am10-894 |
0.325 |
|
2010 |
Levin PA, Arumugam T, McConkey DJ, Reddy S, Logsdon CD. Abstract 3920: EphA2 transcription is regulated by activation of Ras / MEK2 / cytoplasmic ERK pathway in pancreatic cancer Cancer Research. 70: 3920-3920. DOI: 10.1158/1538-7445.Am10-3920 |
0.392 |
|
2010 |
Pino MS, Shrader M, Baker CH, Cognetti F, Xiong HQ, Abbruzzese JL, McConkey D. Correction: Transforming growth factor α expression drives constitutive epidermal growth factor receptor pathway activation and sensitivity to gefitinib (Iressa) in human pancreatic cancer cell lines (Cancer Research (2006) 66, 7, (3802-3812)) Cancer Research. 70: 852-853. DOI: 10.1158/0008-5472.Can-09-4221 |
0.779 |
|
2010 |
Svatek R, Xing J, Chang D, Shah J, Lin J, McConkey D, Wu X, Dinney C. 1713 A MULTIPLEXED, PARTICLE BASED FLOW CYTOMETRIC ASSAY IDENTIFIED MMP7 TO BE ASSOCIATED WITH CANCER RELATED DEATH AMONG PATIENTS WITH BLADDER CANCER Journal of Urology. 183. DOI: 10.1016/J.Juro.2010.02.1560 |
0.331 |
|
2009 |
McConkey DJ, Dinney C. Urological cancers. Preface. Cancer Metastasis Reviews. 28: 267. PMID 20013034 DOI: 10.1007/S10555-009-9191-X |
0.33 |
|
2009 |
McConkey DJ, Choi W, Marquis L, Martin F, Williams MB, Shah J, Svatek R, Das A, Adam L, Kamat A, Siefker-Radtke A, Dinney C. Role of epithelial-to-mesenchymal transition (EMT) in drug sensitivity and metastasis in bladder cancer. Cancer Metastasis Reviews. 28: 335-44. PMID 20012924 DOI: 10.1007/S10555-009-9194-7 |
0.429 |
|
2009 |
McConkey DJ, Dinney CP. The molecular, the bad, and the ugly: preventing bladder cancer via mTOR inhibition. Cancer Prevention Research (Philadelphia, Pa.). 2: 1001-2. PMID 19952365 DOI: 10.1158/1940-6207.Capr-09-0235 |
0.365 |
|
2009 |
Adam L, Zhong M, Choi W, Qi W, Nicoloso M, Arora A, Calin G, Wang H, Siefker-Radtke A, McConkey D, Bar-Eli M, Dinney C. miR-200 expression regulates epithelial-to-mesenchymal transition in bladder cancer cells and reverses resistance to epidermal growth factor receptor therapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 5060-72. PMID 19671845 DOI: 10.1158/1078-0432.Ccr-08-2245 |
0.406 |
|
2009 |
Arumugam T, Ramachandran V, Fournier KF, Wang H, Marquis L, Abbruzzese JL, Gallick GE, Logsdon CD, McConkey DJ, Choi W. Epithelial to mesenchymal transition contributes to drug resistance in pancreatic cancer. Cancer Research. 69: 5820-8. PMID 19584296 DOI: 10.1158/0008-5472.Can-08-2819 |
0.429 |
|
2009 |
Lopez G, Liu J, Ren W, Wei W, Wang S, Lahat G, Zhu QS, Bornmann WG, McConkey DJ, Pollock RE, Lev DC. Combining PCI-24781, a novel histone deacetylase inhibitor, with chemotherapy for the treatment of soft tissue sarcoma Clinical Cancer Research. 15: 3472-3483. PMID 19417021 DOI: 10.1158/1078-0432.Ccr-08-2714 |
0.324 |
|
2009 |
Zhu K, Chan W, Heymach J, Wilkinson M, McConkey DJ. Control of HIF-1alpha expression by eIF2 alpha phosphorylation-mediated translational repression. Cancer Research. 69: 1836-43. PMID 19244104 DOI: 10.1158/0008-5472.Can-08-4103 |
0.774 |
|
2009 |
Fisher MB, Zhang XQ, McConkey DJ, Benedict WF. Measuring soluble forms of extracellular cytokeratin 18 identifies both apoptotic and necrotic mechanisms of cell death produced by adenoviral-mediated interferon α: PPPossible use as a surrogate marker Cancer Gene Therapy. 16: 567-572. PMID 19197325 DOI: 10.1038/Cgt.2009.2 |
0.42 |
|
2009 |
Haddad Y, Choi W, McConkey DJ. Delta-crystallin enhancer binding factor 1 controls the epithelial to mesenchymal transition phenotype and resistance to the epidermal growth factor receptor inhibitor erlotinib in human head and neck squamous cell carcinoma lines. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 532-42. PMID 19147758 DOI: 10.1158/1078-0432.Ccr-08-1733 |
0.788 |
|
2009 |
Raut CP, Takamori RK, Davis DW, Sweeney-Gotsch B, O'Reilly MS, McConkey DJ. Direct effects of recombinant human endostatin on tumor cell IL-8 production are associated with increased endothelial cell apoptosis in an orthotopic model of human pancreatic cancer (Cancer Biology and Therapy (2004) 3, 7, (679-87) Cancer Biology & Therapy. 8. DOI: 10.4161/Cbt.8.10.9069 |
0.448 |
|
2009 |
Fournier K, Choi W, Maarquis L, McConkey DJ. Abstract B70: Histone deacetylase inhibitors reverse EMT phenotype and chemoresistance in pancreatic cancer cell lines Molecular Cancer Therapeutics. 8. DOI: 10.1158/1535-7163.Targ-09-B70 |
0.468 |
|
2009 |
Shah JB, Marquis LM, Svatek RS, Papadopoulos JN, Dinney CP, McConkey DJ. THE MITOTOIC SPINDLE APPARATUS INHIBITOR AZD4877 HOLDS PROMISE AS A NOVEL THERAPEUTIC OPTION AGAINST HUMAN BLADDER CANCER Journal of Urology. 181: 410-410. DOI: 10.1016/S0022-5347(09)61165-4 |
0.484 |
|
2008 |
Pan X, Arumugam T, Yamamoto T, Levin PA, Ramachandran V, Ji B, Lopez-Berestein G, Vivas-Mejia PE, Sood AK, McConkey DJ, Logsdon CD. Nuclear factor-kappaB p65/relA silencing induces apoptosis and increases gemcitabine effectiveness in a subset of pancreatic cancer cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 8143-51. PMID 19088029 DOI: 10.1158/1078-0432.Ccr-08-1539 |
0.483 |
|
2008 |
McConkey DJ, Zhu K. Mechanisms of proteasome inhibitor action and resistance in cancer. Drug Resistance Updates : Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy. 11: 164-79. PMID 18818117 DOI: 10.1016/J.Drup.2008.08.002 |
0.824 |
|
2008 |
Kim KB, Eton O, Davis DW, Frazier ML, McConkey DJ, Diwan AH, Papadopoulos NE, Bedikian AY, Camacho LH, Ross MI, Cormier JN, Gershenwald JE, Lee JE, Mansfield PF, Billings LA, et al. Phase II trial of imatinib mesylate in patients with metastatic melanoma. British Journal of Cancer. 99: 734-40. PMID 18728664 DOI: 10.1038/Sj.Bjc.6604482 |
0.363 |
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2008 |
Pino MS, Balsamo M, Di Modugno F, Mottolese M, Alessio M, Melucci E, Milella M, McConkey DJ, Philippar U, Gertler FB, Natali PG, Nisticò P. Human Mena+11a isoform serves as a marker of epithelial phenotype and sensitivity to epidermal growth factor receptor inhibition in human pancreatic cancer cell lines. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 4943-50. PMID 18676769 DOI: 10.1158/1078-0432.Ccr-08-0436 |
0.459 |
|
2008 |
Zhou J, Zhang XQ, Ashoori F, McConkey DJ, Knowles MA, Dong L, Benedict WF. Early RB94-produced cytotoxicity in cancer cells is independent of caspase activation or 50 kb DNA fragmentation. Cancer Gene Therapy. 16: 13-9. PMID 18654611 DOI: 10.1038/Cgt.2008.54 |
0.498 |
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2008 |
Nawrocki ST, Carew JS, Maclean KH, Courage JF, Huang P, Houghton JA, Cleveland JL, Giles FJ, McConkey DJ. Myc regulates aggresome formation, the induction of Noxa, and apoptosis in response to the combination of bortezomib and SAHA. Blood. 112: 2917-26. PMID 18641367 DOI: 10.1182/Blood-2007-12-130823 |
0.691 |
|
2008 |
Kassouf W, Brown GA, Black PC, Fisher MB, Inamoto T, Luongo T, Gallagher D, Bar-Eli M, McConkey DJ, Adam L, Dinney CP. Is vascular endothelial growth factor modulation a predictor of the therapeutic efficacy of gefitinib for bladder cancer? The Journal of Urology. 180: 1146-53. PMID 18639280 DOI: 10.1016/J.Juro.2008.05.001 |
0.368 |
|
2008 |
McConkey DJ. A novel role for a familiar protein in apoptosis induced by proteasome inhibition. Cancer Cell. 14: 1-2. PMID 18598936 DOI: 10.1016/J.Ccr.2008.06.011 |
0.483 |
|
2008 |
Majewski T, Lee S, Jeong J, Yoon DS, Kram A, Kim MS, Tuziak T, Bondaruk J, Lee S, Park WS, Tang KS, Chung W, Shen L, Ahmed SS, Johnston DA, ... ... McConkey DJ, et al. Understanding the development of human bladder cancer by using a whole-organ genomic mapping strategy. Laboratory Investigation; a Journal of Technical Methods and Pathology. 88: 694-721. PMID 18458673 DOI: 10.1038/Labinvest.2008.27 |
0.304 |
|
2008 |
Black PC, Brown GA, Inamoto T, Shrader M, Arora A, Siefker-Radtke AO, Adam L, Theodorescu D, Wu X, Munsell MF, Bar-Eli M, McConkey DJ, Dinney CP. Sensitivity to epidermal growth factor receptor inhibitor requires E-cadherin expression in urothelial carcinoma cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 1478-86. PMID 18316572 DOI: 10.1158/1078-0432.Ccr-07-1593 |
0.761 |
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2008 |
Cultrera JL, Rosenberg L, McConkey DJ, Pro B. The Histone Deacetylase Inhibitor Vorinostat Induces Apoptosis in T-Cell Lymphoma Cell Lines and Synergizes with Bortezomib. Blood. 112: 1587-1587. DOI: 10.1182/Blood.V112.11.1587.1587 |
0.454 |
|
2008 |
Inamoto T, Black PC, Fisher MB, Hegarty PK, Arora A, Adam L, McConkey DJ, Dinney CP. E-CADHERIN EXPRESSION POTENTIATES ERLOTINIB TREATMENT IN BLADDER CANCER Journal of Urology. 179: 372-372. DOI: 10.1016/S0022-5347(08)61088-5 |
0.401 |
|
2008 |
Inamoto T, Papineni S, Chintharlapalli S, Cho S, Black PC, McConkey DJ, Dinney CP, Safe SH, Kamat AM. A NOVEL ACTIVATOR OF THE ORPHAN NUCLEAR RECEPTOR Nurr1 INHIBITS BLADDER TUMOR GROWTH Journal of Urology. 179: 369-369. DOI: 10.1016/S0022-5347(08)61081-2 |
0.343 |
|
2007 |
McConkey DJ. Therapy-induced apoptosis in primary tumors. Advances in Experimental Medicine and Biology. 608: 31-51. PMID 17993231 DOI: 10.1007/978-0-387-74039-3_3 |
0.462 |
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2007 |
Agarwal PK, Black PC, McConkey DJ, Dinney CP. Emerging drugs for targeted therapy of bladder cancer. Expert Opinion On Emerging Drugs. 12: 435-48. PMID 17874971 DOI: 10.1517/14728214.12.3.435 |
0.389 |
|
2007 |
Lee S, Jeong J, Majewski T, Scherer SE, Kim MS, Tuziak T, Tang KS, Baggerly K, Grossman HB, Zhou JH, Shen L, Bondaruk J, Ahmed SS, Samanta S, Spiess P, ... ... McConkey D, et al. Forerunner genes contiguous to RB1 contribute to the development of in situ neoplasia. Proceedings of the National Academy of Sciences of the United States of America. 104: 13732-7. PMID 17702869 DOI: 10.1073/Pnas.0701771104 |
0.331 |
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2007 |
Villares GJ, Zigler M, Blehm K, Bogdan C, McConkey D, Colin D, Bar-Eli M. Targeting EGFR in bladder cancer. World Journal of Urology. 25: 573-9. PMID 17690890 DOI: 10.1007/S00345-007-0202-7 |
0.381 |
|
2007 |
Papageorgiou A, Dinney CP, McConkey DJ. Interferon-alpha induces TRAIL expression and cell death via an IRF-1-dependent mechanism in human bladder cancer cells. Cancer Biology & Therapy. 6: 872-9. PMID 17617740 DOI: 10.4161/Cbt.6.6.4088 |
0.512 |
|
2007 |
Adam L, Black PC, Kassouf W, Eve B, McConkey D, Munsell MF, Benedict WF, Dinney CP. Adenoviral mediated interferon-alpha 2b gene therapy suppresses the pro-angiogenic effect of vascular endothelial growth factor in superficial bladder cancer. The Journal of Urology. 177: 1900-6. PMID 17437845 DOI: 10.1016/J.Juro.2007.01.003 |
0.376 |
|
2007 |
Miller CP, Ban K, Dujka ME, McConkey DJ, Munsell M, Palladino M, Chandra J. NPI-0052, a novel proteasome inhibitor, induces caspase-8 and ROS-dependent apoptosis alone and in combination with HDAC inhibitors in leukemia cells. Blood. 110: 267-77. PMID 17356134 DOI: 10.1182/Blood-2006-03-013128 |
0.488 |
|
2007 |
Shrader M, Pino MS, Lashinger L, Bar-Eli M, Adam L, Dinney CP, McConkey DJ. Gefitinib reverses TRAIL resistance in human bladder cancer cell lines via inhibition of AKT-mediated X-linked inhibitor of apoptosis protein expression. Cancer Research. 67: 1430-5. PMID 17308080 DOI: 10.1158/0008-5472.Can-06-1224 |
0.838 |
|
2007 |
Shrader M, Pino MS, Brown G, Black P, Adam L, Bar-Eli M, Dinney CP, McConkey DJ. Molecular correlates of gefitinib responsiveness in human bladder cancer cells. Molecular Cancer Therapeutics. 6: 277-85. PMID 17237287 DOI: 10.1158/1535-7163.Mct-06-0513 |
0.793 |
|
2007 |
Pino SM, Xiong HQ, McConkey D, Abbruzzese JL. Novel therapies for pancreatic adenocarcinoma. Current Oncology Reports. 6: 199-206. PMID 15066231 DOI: 10.1007/S11912-004-0050-1 |
0.41 |
|
2007 |
Abbruzzese J, Kurzrock R, McConkey D, Xie K, Safe S, Halder G, Hung M, Evans D. 149 INVITED Are there rational novel targets for pancreatic cancer therapeutics? Observations from the M.D. Anderson Cancer Center SPORE in Pancreatic Cancer European Journal of Cancer Supplements. 5: 41. DOI: 10.1016/S1359-6349(07)70263-X |
0.335 |
|
2006 |
Papageorgiou A, Kamat A, Benedict WF, Dinney C, McConkey DJ. Combination therapy with IFN-alpha plus bortezomib induces apoptosis and inhibits angiogenesis in human bladder cancer cells. Molecular Cancer Therapeutics. 5: 3032-41. PMID 17172406 DOI: 10.1158/1535-7163.Mct-05-0474 |
0.486 |
|
2006 |
Zhang X, Yang Z, Dong L, Papageorgiou A, McConkey DJ, Benedict WF. Adenoviral-mediated interferon alpha overcomes resistance to the interferon protein in various cancer types and has marked bystander effects. Cancer Gene Therapy. 14: 241-50. PMID 17096027 DOI: 10.1038/Sj.Cgt.7701011 |
0.447 |
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2006 |
Walterscheid JP, Nghiem DX, Kazimi N, Nutt LK, McConkey DJ, Norval M, Ullrich SE. Cis-urocanic acid, a sunlight-induced immunosuppressive factor, activates immune suppression via the 5-HT2A receptor. Proceedings of the National Academy of Sciences of the United States of America. 103: 17420-5. PMID 17085585 DOI: 10.1073/Pnas.0603119103 |
0.694 |
|
2006 |
Khanbolooki S, Nawrocki ST, Arumugam T, Andtbacka R, Pino MS, Kurzrock R, Logsdon CD, Abbruzzese JL, McConkey DJ. Nuclear factor-kappaB maintains TRAIL resistance in human pancreatic cancer cells. Molecular Cancer Therapeutics. 5: 2251-60. PMID 16985059 DOI: 10.1158/1535-7163.Mct-06-0075 |
0.829 |
|
2006 |
Canfield SE, Zhu K, Williams SA, McConkey DJ. Bortezomib inhibits docetaxel-induced apoptosis via a p21-dependent mechanism in human prostate cancer cells. Molecular Cancer Therapeutics. 5: 2043-50. PMID 16928825 DOI: 10.1158/1535-7163.Mct-05-0437 |
0.821 |
|
2006 |
Blehm KN, Spiess PE, Bondaruk JE, Dujka ME, Villares GJ, Zhao YJ, Bogler O, Aldape KD, Grossman HB, Adam L, McConkey DJ, Czerniak BA, Dinney CP, Bar-Eli M. Mutations within the kinase domain and truncations of the epidermal growth factor receptor are rare events in bladder cancer: implications for therapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 4671-7. PMID 16899617 DOI: 10.1158/1078-0432.Ccr-06-0407 |
0.316 |
|
2006 |
Ruiz S, Krupnik Y, Keating M, Chandra J, Palladino M, McConkey D. The proteasome inhibitor NPI-0052 is a more effective inducer of apoptosis than bortezomib in lymphocytes from patients with chronic lymphocytic leukemia. Molecular Cancer Therapeutics. 5: 1836-43. PMID 16891470 DOI: 10.1158/1535-7163.Mct-06-0066 |
0.823 |
|
2006 |
Trevino JG, Gray MJ, Nawrocki ST, Summy JM, Lesslie DP, Evans DB, Sawyer TK, Shakespeare WC, Watowich SS, Chiao PJ, McConkey DJ, Gallick GE. Src activation of Stat3 is an independent requirement from NF-kappaB activation for constitutive IL-8 expression in human pancreatic adenocarcinoma cells. Angiogenesis. 9: 101-10. PMID 16871430 DOI: 10.1007/S10456-006-9038-9 |
0.603 |
|
2006 |
Pino MS, Shrader M, Baker CH, Cognetti F, Xiong HQ, Abbruzzese JL, McConkey DJ. Transforming growth factor alpha expression drives constitutive epidermal growth factor receptor pathway activation and sensitivity to gefitinib (Iressa) in human pancreatic cancer cell lines. Cancer Research. 66: 3802-12. PMID 16585207 DOI: 10.1158/0008-5472.Can-05-3753 |
0.794 |
|
2006 |
Nawrocki ST, Carew JS, Pino MS, Highshaw RA, Andtbacka RHI, Dunner K, Pal A, Bornmann WG, Chiao PJ, Huang P, Xiong H, Abbruzzese JL, McConkey DJ. Aggresome disruption: A novel strategy to enhance bortezomib-induced apoptosis in pancreatic cancer cells Cancer Research. 66: 3773-3781. PMID 16585204 DOI: 10.1158/0008-5472.Can-05-2961 |
0.715 |
|
2006 |
Carew JS, Nawrocki ST, Krupnik YV, Dunner K, McConkey DJ, Keating MJ, Huang P. Targeting endoplasmic reticulum protein transport: a novel strategy to kill malignant B cells and overcome fludarabine resistance in CLL. Blood. 107: 222-31. PMID 16144803 DOI: 10.1182/Blood-2005-05-1923 |
0.671 |
|
2006 |
Zhu K, Pino M, Siefker-Radtke AO, Shalinsky D, Hu-Lowe D, McConkey DJ. AG-013736, a novel VEGF receptor and PDGF receptor inhibitor with potent activity against human bladder carcinoma in vitro and in vivo. Journal of Clinical Oncology. 24: 13109-13109. DOI: 10.1200/Jco.2006.24.18_Suppl.13109 |
0.804 |
|
2006 |
Yazbeck VY, Georgakis GV, Li Y, McConkey D, Andreeff M, Younes A. Inhibition of the Pan-Bcl-2 Family by the Small Molecule GX15-070 Induces Apoptosis in Mantle Cell Lymphoma (MCL) Cells and Enhances the Activity of Two Proteasome Inhibitors (NPI-0052 and Bortezomib), and Doxorubicin Chemotherapy. Blood. 108: 2532-2532. DOI: 10.1182/Blood.V108.11.2532.2532 |
0.494 |
|
2006 |
Pino M, Balsamo M, Di Modugno F, Conidi A, McConkey D, Cognetti F, Natali P, Miella M, Nisticò P. 558 POSTER Epithelial mesenchymal transition (EMT) and hMena expression as determinants of sensitivity of pancreatic adenocarcinoma (PDAC) cell lines to EGFR tyrosine kinase Inhibitors (TKI) European Journal of Cancer Supplements. 4: 169. DOI: 10.1016/S1359-6349(06)70563-8 |
0.376 |
|
2006 |
McConkey D, Shrader M, Pino M, Adam L, Dinney C. 478 POSTER Gefitinib reverses TRAIL resistance in human bladder cancer cell lines via inhibition of AKT-mediated XIAP expression European Journal of Cancer Supplements. 4: 146. DOI: 10.1016/S1359-6349(06)70483-9 |
0.804 |
|
2006 |
Pino M, Milella M, Gelibter A, Felici A, Cognetti F, McConkey D. 425 POSTER Biological role of the CREB/COX-2 pathway in the regulation of human pancreatic cancer proliferation and survival European Journal of Cancer Supplements. 4: 130. DOI: 10.1016/S1359-6349(06)70430-X |
0.365 |
|
2006 |
Adam L, Black P, Brown G, Munsell M, Kassouf W, Nicola P, Dinney C, McConkey D, Bar-Eli M. 206 POSTER EGFR and PDGFR crosstalk may dictate the resistance to EGFR therapy in bladder cancer European Journal of Cancer Supplements. 4: 64. DOI: 10.1016/S1359-6349(06)70211-7 |
0.347 |
|
2006 |
Davis D, McConkey D, Heymach J, Desai J, George S, DePrimo S, Bello C, Baum C, Demetri G. 57 POSTER Correlation of receptor tyrosine kinase (RTK) activity and paoptosis with response to sunitinib treatment in patients with gastrointestinal stromal tumor (GIST) European Journal of Cancer Supplements. 4: 21-22. DOI: 10.1016/S1359-6349(06)70063-5 |
0.313 |
|
2006 |
Adam L, Kassouf W, McConkey D, Munsell MF, Benedict W, Dinney CP. 838: Adenoviral-Mediated IFNα2B Expression Suppresses Proangiogenic Factors in Bladder Cancer Journal of Urology. 175: 270-270. DOI: 10.1016/S0022-5347(18)33074-X |
0.373 |
|
2005 |
Davis DW, McConkey DJ, Heymach JV, Desai J, George S, Jackson J, Bello CL, Baum C, Shalinsky DR, Demetri GD. Pharmacodynamic analysis of target receptor tyrosine kinase activity and apoptosis in GIST tumors responding to therapy with SU11248. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 23: 3006. PMID 27945727 DOI: 10.1200/Jco.2005.23.16_Suppl.3006 |
0.362 |
|
2005 |
Trent JC, Choi H, Hunt K, Macapinlac H, McConkey D, Charnsangravej C, Abbruzzese J, Benjamin RS, Davis D. Apoptotic and anti-vascular activity of imatinib in GIST patients. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 23: 9001. PMID 27945517 DOI: 10.1200/Jco.2005.23.16_Suppl.9001 |
0.355 |
|
2005 |
Nawrocki ST, Carew JS, Pino MS, Highshaw RA, Dunner K, Huang P, Abbruzzese JL, McConkey DJ. Bortezomib sensitizes pancreatic cancer cells to endoplasmic reticulum stress-mediated apoptosis. Cancer Research. 65: 11658-66. PMID 16357177 DOI: 10.1158/0008-5472.Can-05-2370 |
0.689 |
|
2005 |
Nawrocki ST, Carew JS, Dunner K, Boise LH, Chiao PJ, Huang P, Abbruzzese JL, McConkey DJ. Bortezomib inhibits PKR-like endoplasmic reticulum (ER) kinase and induces apoptosis via ER stress in human pancreatic cancer cells. Cancer Research. 65: 11510-9. PMID 16357160 DOI: 10.1158/0008-5472.Can-05-2394 |
0.677 |
|
2005 |
Pino MS, Nawrocki ST, Cognetti F, Abruzzese JL, Xiong HQ, McConkey DJ. Prostaglandin E2 drives cyclooxygenase-2 expression via cyclic AMP response element activation in human pancreatic cancer cells. Cancer Biology & Therapy. 4: 1263-9. PMID 16319525 DOI: 10.4161/Cbt.4.11.2138 |
0.671 |
|
2005 |
Kassouf W, Dinney CP, Brown G, McConkey DJ, Diehl AJ, Bar-Eli M, Adam L. Uncoupling between epidermal growth factor receptor and downstream signals defines resistance to the antiproliferative effect of Gefitinib in bladder cancer cells. Cancer Research. 65: 10524-35. PMID 16288045 DOI: 10.1158/0008-5472.Can-05-1536 |
0.416 |
|
2005 |
Lashinger LM, Zhu K, Williams SA, Shrader M, Dinney CP, McConkey DJ. Bortezomib abolishes tumor necrosis factor-related apoptosis-inducing ligand resistance via a p21-dependent mechanism in human bladder and prostate cancer cells. Cancer Research. 65: 4902-8. PMID 15930312 DOI: 10.1158/0008-5472.Can-04-3701 |
0.825 |
|
2005 |
McConkey D, Nawrocki ST, Andtbacka R. Velcade displays promising activity in primary effusion lymphoma cells. Cancer Biology & Therapy. 4: 491-2. PMID 15908793 DOI: 10.4161/Cbt.4.4.1645 |
0.668 |
|
2005 |
Nutt LK, Gogvadze V, Uthaisang W, Mirnikjoo B, McConkey DJ, Orrenius S. Indirect effects of Bax and Bak initiate the mitochondrial alterations that lead to cytochrome c release during arsenic trioxide-induced apoptosis. Cancer Biology & Therapy. 4: 459-67. PMID 15846091 DOI: 10.4161/Cbt.4.4.1652 |
0.749 |
|
2005 |
Miller CP, Ban K, Ruiz SL, Neuteboom S, Palladino M, McConkey D, Chandra J. The Novel, Orally Active Proteasome Inhibitor, NPI-0052, Induces Apoptosis in Leukemia Lymphoma Cell Lines and Patient Specimens. Blood. 106: 241-241. DOI: 10.1182/Blood.V106.11.241.241 |
0.832 |
|
2004 |
Papageorgiou A, Lashinger L, Millikan R, Grossman HB, Benedict W, Dinney CP, McConkey DJ. Role of tumor necrosis factor-related apoptosis-inducing ligand in interferon-induced apoptosis in human bladder cancer cells. Cancer Research. 64: 8973-9. PMID 15604261 DOI: 10.1158/0008-5472.Can-04-1909 |
0.786 |
|
2004 |
Carew JS, Nawrocki ST, Xu RH, Dunner K, McConkey DJ, Wierda WG, Keating MJ, Huang P. Increased mitochondrial biogenesis in primary leukemia cells: the role of endogenous nitric oxide and impact on sensitivity to fludarabine. Leukemia. 18: 1934-40. PMID 15483672 DOI: 10.1038/Sj.Leu.2403545 |
0.603 |
|
2004 |
Raut CP, Nawrocki S, Lashinger LM, Davis DW, Khanbolooki S, Xiong H, Ellis LM, McConkey DJ. Celecoxib inhibits angiogenesis by inducing endothelial cell apoptosis in human pancreatic tumor xenografts. Cancer Biology & Therapy. 3: 1217-24. PMID 15477758 DOI: 10.4161/Cbt.3.12.1221 |
0.796 |
|
2004 |
Benedict WF, Tao Z, Kim CS, Zhang X, Zhou JH, Adam L, McConkey DJ, Papageorgiou A, Munsell M, Philopena J, Engler H, Demers W, Maneval DC, Dinney CP, Connor RJ. Intravesical Ad-IFNalpha causes marked regression of human bladder cancer growing orthotopically in nude mice and overcomes resistance to IFN-alpha protein. Molecular Therapy : the Journal of the American Society of Gene Therapy. 10: 525-32. PMID 15336652 DOI: 10.1016/J.Ymthe.2004.05.027 |
0.393 |
|
2004 |
Davis DW, Inoue K, Dinney CP, Hicklin DJ, Abbruzzese JL, McConkey DJ. Regional effects of an antivascular endothelial growth factor receptor monoclonal antibody on receptor phosphorylation and apoptosis in human 253J B-V bladder cancer xenografts. Cancer Research. 64: 4601-10. PMID 15231672 DOI: 10.1158/0008-5472.Can-2879-2 |
0.391 |
|
2004 |
Raut CP, Takamori RK, Davis DW, Sweeney-Gotsch B, O'Reilly MS, McConkey DJ. Direct effects of recombinant human endostatin on tumor cell IL-8 production are associated with increased endothelial cell apoptosis in an orthotopic model of human pancreatic cancer. Cancer Biology & Therapy. 3: 679-87. PMID 15197351 DOI: 10.4161/Cbt.3.7.967 |
0.42 |
|
2004 |
Cortes J, Thomas D, Koller C, Giles F, Estey E, Faderl S, Garcia-Manero G, McConkey D, Ruiz SL, Patel G, Guerciolini R, Wright J, Kantarjian H. Phase I study of bortezomib in refractory or relapsed acute leukemias. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 3371-6. PMID 15161691 DOI: 10.1158/1078-0432.Ccr-03-0508 |
0.77 |
|
2004 |
Zheng B, Georgakis GV, Li Y, Bharti A, McConkey DJ, Aggarwal BB, Younes A. Induction of cell cycle arrest and apoptosis by the proteasome inhibitor PS-341 in Hodgkin disease cell lines is independent of inhibitor of nuclear factor-κB mutations or activation of the CD30, CD40, and RANK receptors Clinical Cancer Research. 10: 3207-3215. PMID 15131062 DOI: 10.1158/1078-0432.Ccr-03-0494 |
0.479 |
|
2004 |
McConkey DJ, Nutt L. Measurement of changes in intracellular calcium during apoptosis. Methods in Molecular Biology (Clifton, N.J.). 282: 117-30. PMID 15105560 DOI: 10.1385/1-59259-812-9:117 |
0.712 |
|
2004 |
Kamat AM, Karashima T, Davis DW, Lashinger L, Bar-Eli M, Millikan R, Shen Y, Dinney CP, McConkey DJ. The proteasome inhibitor bortezomib synergizes with gemcitabine to block the growth of human 253JB-V bladder tumors in vivo. Molecular Cancer Therapeutics. 3: 279-90. PMID 15026548 |
0.738 |
|
2004 |
Nawrocki ST, Sweeney-Gotsch B, Takamori R, McConkey DJ. The proteasome inhibitor bortezomib enhances the activity of docetaxel in orthotopic human pancreatic tumor xenografts. Molecular Cancer Therapeutics. 3: 59-70. PMID 14749476 |
0.686 |
|
2004 |
McConkey DJ, Orrenius S. Signal transduction pathways to apoptosis. Trends in Cell Biology. 4: 370-5. PMID 14731626 DOI: 10.1016/0962-8924(94)90087-6 |
0.353 |
|
2004 |
Faderl S, Rai KR, Gribben J, Flinn I, Byrd JC, McConkey D, Schenkein D, Esseltine D, Browning ML, Keating MJ. Phase 2 Study of Three Doses of Single Agent Bortezomib in Patients with Fludarabine-Refractory B-Cell CLL. Blood. 104: 4841-4841. DOI: 10.1182/Blood.V104.11.4841.4841 |
0.315 |
|
2003 |
Williams S, Pettaway C, Song R, Papandreou C, Logothetis C, McConkey DJ. Differential effects of the proteasome inhibitor bortezomib on apoptosis and angiogenesis in human prostate tumor xenografts. Molecular Cancer Therapeutics. 2: 835-43. PMID 14555702 |
0.405 |
|
2003 |
Pahler JC, Ruiz S, Niemer I, Calvert LR, Andreeff M, Keating M, Faderl S, McConkey DJ. Effects of the proteasome inhibitor, bortezomib, on apoptosis in isolated lymphocytes obtained from patients with chronic lymphocytic leukemia. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 4570-7. PMID 14555532 |
0.781 |
|
2003 |
Davis DW, McConkey DJ, Abbruzzese JL, Herbst RS. Surrogate markers in antiangiogenesis clinical trials. British Journal of Cancer. 89: 8-14. PMID 12838293 DOI: 10.1038/Sj.Bjc.6601035 |
0.3 |
|
2003 |
Yang P, Collin P, Madden T, Chan D, Sweeney-Gotsch B, McConkey DJ, Newman RA. Inhibition of proliferation of PC3 cells by the branched‐chain fatty acid, 12‐methyltetradecanoic acid, is associated with inhibition of 5‐lipoxygenase The Prostate. 55: 281-291. PMID 12712407 DOI: 10.1002/Pros.10243 |
0.475 |
|
2003 |
Davis DW, Buchholz TA, Hess KR, Sahin AA, Valero V, McConkey DJ. Automated quantification of apoptosis after neoadjuvant chemotherapy for breast cancer: early assessment predicts clinical response. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 955-60. PMID 12631592 |
0.336 |
|
2003 |
Buchholz TA, Davis DW, McConkey DJ, Symmans WF, Valero V, Jhingran A, Tucker SL, Pusztai L, Cristofanilli M, Esteva FJ, Hortobagyi GN, Sahin AA. Chemotherapy-induced apoptosis and Bcl-2 levels correlate with breast cancer response to chemotherapy. Cancer Journal (Sudbury, Mass.). 9: 33-41. PMID 12602766 DOI: 10.1097/00130404-200301000-00007 |
0.404 |
|
2003 |
Zhang X, Multani AS, Zhou JH, Shay JW, McConkey D, Dong L, Kim CS, Rosser CJ, Pathak S, Benedict WF. Adenoviral-mediated retinoblastoma 94 produces rapid telomere erosion, chromosomal crisis, and caspase-dependent apoptosis in bladder cancer and immortalized human urothelial cells but not in normal urothelial cells Cancer Research. 63: 760-765. PMID 12591722 |
0.372 |
|
2002 |
Cao XX, Mohuiddin I, Chada S, Mhashilkar AM, Ozvaran MK, McConkey DJ, Miller SD, Daniel JC, Smythe WR. Adenoviral transfer of mda-7 leads to BAX up-regulation and apoptosis in mesothelioma cells, and is abrogated by over-expression of BCL-XL. Molecular Medicine (Cambridge, Mass.). 8: 869-76. PMID 12606823 DOI: 10.1007/Bf03402093 |
0.446 |
|
2002 |
Nawrocki ST, Bruns CJ, Harbison MT, Bold RJ, Gotsch BS, Abbruzzese JL, Elliott P, Adams J, McConkey DJ. Effects of the proteasome inhibitor ps-341 on apoptosis and angiogenesis in orthotopic human pancreatic tumor xenografts Molecular Cancer Therapeutics. 1: 1243-1253. PMID 12516957 |
0.66 |
|
2002 |
Bondar VM, Sweeney-Gotsch B, Andreeff M, Mills GB, McConkey DJ. Inhibition of the phosphatidylinositol 3'-kinase-AKT pathway induces apoptosis in pancreatic carcinoma cells in vitro and in vivo. Molecular Cancer Therapeutics. 1: 989-97. PMID 12481421 |
0.374 |
|
2002 |
Windham TC, Parikh NU, Siwak DR, Summy JM, McConkey DJ, Kraker AJ, Gallick GE. Src activation regulates anoikis in human colon tumor cell lines. Oncogene. 21: 7797-807. PMID 12420216 DOI: 10.1038/Sj.Onc.1205989 |
0.474 |
|
2002 |
Herbst RS, Mullani NA, Davis DW, Hess KR, McConkey DJ, Charnsangavej C, O'Reilly MS, Kim HW, Baker C, Roach J, Ellis LM, Rashid A, Pluda J, Bucana C, Madden TL, et al. Development of biologic markers of response and assessment of antiangiogenic activity in a clinical trial of human recombinant endostatin. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 20: 3804-14. PMID 12228200 DOI: 10.1200/Jco.2002.05.102 |
0.31 |
|
2002 |
Herbst RS, Hess KR, Tran HT, Tseng JE, Mullani NA, Charnsangavej C, Madden T, Davis DW, McConkey DJ, O'Reilly MS, Ellis LM, Pluda J, Hong WK, Abbruzzese JL. Phase I study of recombinant human endostatin in patients with advanced solid tumors. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 20: 3792-803. PMID 12228199 DOI: 10.1200/Jco.2002.11.061 |
0.315 |
|
2002 |
Termuhlen PM, Sweeney-Gotsch BM, Berman RS, Ellis LM, Bucana C, Shen Y, Cleary KR, McConkey DJ. Increased apoptosis in metastatic human colonic adenocarcinomas. Cancer Biology & Therapy. 1: 58-63. PMID 12170764 DOI: 10.4161/Cbt.1.1.43 |
0.488 |
|
2002 |
Guo Z, Clydesdale G, Cheng J, Kim K, Gan L, McConkey DJ, Ullrich SE, Zhuang Y, Su B. Disruption of Mekk2 in mice reveals an unexpected role for MEKK2 in modulating T-cell receptor signal transduction. Molecular and Cellular Biology. 22: 5761-8. PMID 12138187 DOI: 10.1128/Mcb.22.16.5761-5768.2002 |
0.326 |
|
2002 |
Santamaria AB, Davis DW, Nghiem DX, McConkey DJ, Ullrich SE, Kapoor M, Lozano G, Ananthaswamy HN. p53 and Fas ligand are required for psoralen and UVA-induced apoptosis in mouse epidermal cells. Cell Death and Differentiation. 9: 549-60. PMID 11973613 DOI: 10.1038/Sj.Cdd.4401007 |
0.412 |
|
2002 |
Bondar VM, McConkey DJ. Anoikis is regulated by BCL-2-independent pathways in human prostate carcinoma cells. The Prostate. 51: 42-9. PMID 11920957 DOI: 10.1002/Pros.10070 |
0.445 |
|
2002 |
Nutt LK, Chandra J, Pataer A, Fang B, Roth JA, Swisher SG, O'Neil RG, McConkey DJ. Bax-mediated Ca2+ mobilization promotes cytochrome c release during apoptosis. The Journal of Biological Chemistry. 277: 20301-8. PMID 11909872 DOI: 10.1074/Jbc.M201604200 |
0.727 |
|
2002 |
Nutt LK, Pataer A, Pahler J, Fang B, Roth J, McConkey DJ, Swisher SG. Bax and Bak promote apoptosis by modulating endoplasmic reticular and mitochondrial Ca2+ stores. The Journal of Biological Chemistry. 277: 9219-25. PMID 11741880 DOI: 10.1074/Jbc.M106817200 |
0.774 |
|
2001 |
Cao XX, Mohuiddin I, Ece F, McConkey DJ, Smythe WR. Histone deacetylase inhibitor downregulation of bcl-xl gene expression leads to apoptotic cell death in mesothelioma. American Journal of Respiratory Cell and Molecular Biology. 25: 562-8. PMID 11713097 DOI: 10.1165/Ajrcmb.25.5.4539 |
0.44 |
|
2001 |
Bold RJ, Virudachalam S, McConkey DJ. BCL2 expression correlates with metastatic potential in pancreatic cancer cell lines. Cancer. 92: 1122-9. PMID 11571724 DOI: 10.1002/1097-0142(20010901)92:5<1122::Aid-Cncr1429>3.0.Co;2-H |
0.471 |
|
2001 |
Bold RJ, Virudachalam S, McConkey DJ. Chemosensitization of pancreatic cancer by inhibition of the 26S proteasome. The Journal of Surgical Research. 100: 11-7. PMID 11516199 DOI: 10.1006/Jsre.2001.6194 |
0.444 |
|
2001 |
Nyormoi O, Wang Z, Doan D, Ruiz M, McConkey D, Bar-Eli M. Transcription Factor AP-2α Is Preferentially Cleaved by Caspase 6 and Degraded by Proteasome during Tumor Necrosis Factor Alpha-Induced Apoptosis in Breast Cancer Cells Molecular and Cellular Biology. 21: 4856-4867. PMID 11438643 DOI: 10.1128/Mcb.21.15.4856-4867.2001 |
0.344 |
|
2001 |
McConkey DJ, Nutt LK. Calcium flux measurements in apoptosis. Methods in Cell Biology. 66: 229-46. PMID 11396005 DOI: 10.1016/S0091-679X(01)66011-4 |
0.73 |
|
2001 |
Liu W, Davis DW, Ramirez K, McConkey DJ, Ellis LM. Endothelial cell apoptosis is inhibited by a soluble factor secreted by human colon cancer cells. International Journal of Cancer. Journal International Du Cancer. 92: 26-30. PMID 11279602 DOI: 10.1002/1097-0215(200102)9999:9999<::Aid-Ijc1151>3.0.Co;2-T |
0.481 |
|
2001 |
Pathak S, Multani AS, McConkey DJ, Imam AS, Amoss MS. Spontaneous regression of cutaneous melanoma in sinclair swine is associated with defective telomerase activity and extensive telomere erosion. International Journal of Oncology. 17: 1219-24. PMID 11078808 DOI: 10.3892/Ijo.17.6.1219 |
0.351 |
|
2000 |
Multani AS, Ozen M, Narayan S, Kumar V, Chandra J, McConkey DJ, Newman RA, Pathak S. Caspase-dependent apoptosis induced by telomere cleavage and TRF2 loss. Neoplasia (New York, N.Y.). 2: 339-45. PMID 11005568 DOI: 10.1038/Sj.Neo.7900105 |
0.451 |
|
2000 |
Davis DW, Weidner DA, Holian A, McConkey DJ. Nitric oxide-dependent activation of p53 suppresses bleomycin-induced apoptosis in the lung. The Journal of Experimental Medicine. 192: 857-69. PMID 10993916 DOI: 10.1084/Jem.192.6.857 |
0.352 |
|
2000 |
Bruns CJ, Liu W, Davis DW, Shaheen RM, McConkey DJ, Wilson MR, Bucana CD, Hicklin DJ, Ellis LM. Vascular endothelial growth factor is an in vivo survival factor for tumor endothelium in a murine model of colorectal carcinoma liver metastases. Cancer. 89: 488-99. PMID 10931447 DOI: 10.1002/1097-0142(20000801)89:3<488::Aid-Cncr3>3.0.Co;2-X |
0.3 |
|
2000 |
McConkey DJ, Lin Y, Nutt LK, Ozel HZ, Newman RA. Cardiac glycosides stimulate Ca2+ increases and apoptosis in androgen-independent, metastatic human prostate adenocarcinoma cells. Cancer Research. 60: 3807-12. PMID 10919654 |
0.741 |
|
2000 |
Jean D, Tellez C, Huang S, Davis DW, Bruns CJ, McConkey DJ, Hinrichs SH, Bar-Eli M. Inhibition of tumor growth and metastasis of human melanoma by intracellular anti-ATF-1 single chain Fv fragment. Oncogene. 19: 2721-30. PMID 10851072 DOI: 10.1038/Sj.Onc.1203569 |
0.459 |
|
2000 |
Ouhtit A, Muller HK, Davis DW, Ullrich SE, McConkey D, Ananthaswamy HN. Temporal events in skin injury and the early adaptive responses in ultraviolet-irradiated mouse skin. The American Journal of Pathology. 156: 201-7. PMID 10623668 DOI: 10.1016/S0002-9440(10)64720-7 |
0.381 |
|
2000 |
McConkey DJ. Apoptosis and Cancer Chemotherapy. John A. Hickman , Caroline Dive The Quarterly Review of Biology. 75: 367-368. DOI: 10.1086/393618 |
0.315 |
|
1999 |
Bold RJ, Hess KR, Pearson AS, Grau AM, Sinicrope FA, Jennings M, McConkey DJ, Bucana CD, Cleary KR, Hallin PA, Chiao PJ, Abbruzzese JL, Evans DB. Prognostic Factors in Resectable Pancreatic Cancer: p53 and Bcl-2 Journal of Gastrointestinal Surgery. 3: 263-277. PMID 10481119 DOI: 10.1016/S1091-255X(99)80068-7 |
0.357 |
|
1999 |
McConkey DJ, Chandra J. Protease activation and glucocorticoid-induced apoptosis in chronic lymphocytic leukemia. Leukemia & Lymphoma. 33: 421-31. PMID 10342570 DOI: 10.3109/10428199909058447 |
0.444 |
|
1999 |
Bold RJ, Chandra J, McConkey DJ. Gemcitabine-induced programmed cell death (apoptosis) of human pancreatic carcinoma is determined by Bcl-2 content. Annals of Surgical Oncology. 6: 279-85. PMID 10340887 DOI: 10.1007/S10434-999-0279-X |
0.426 |
|
1999 |
Diaz C, Lee AT, McConkey DJ, Schroit AJ. Phosphatidylserine externalization during differentiation-triggered apoptosis of erythroleukemic cells. Cell Death and Differentiation. 6: 218-26. PMID 10200572 DOI: 10.1038/Sj.Cdd.4400484 |
0.435 |
|
1999 |
McConkey DJ. Biochemical determinants of apoptosis and necrosis. Toxicology Letters. 99: 157-68. PMID 9862281 DOI: 10.1016/S0378-4274(98)00155-6 |
0.427 |
|
1998 |
Bouvet M, Bold RJ, Lee J, Evans DB, Abbruzzese JL, Chiao PJ, McConkey DJ, Chandra J, Chada S, Fang B, Roth JA. Adenovirus-mediated wild-type p53 tumor suppressor gene therapy induces apoptosis and suppresses growth of human pancreatic cancer [seecomments]. Annals of Surgical Oncology. 5: 681-8. PMID 9869513 DOI: 10.1007/Bf02303477 |
0.395 |
|
1998 |
Jean D, Harbison M, McConkey DJ, Ronai Z, Bar-Eli M. CREB and its associated proteins act as survival factors for human melanoma cells. The Journal of Biological Chemistry. 273: 24884-90. PMID 9733794 DOI: 10.1074/Jbc.273.38.24884 |
0.475 |
|
1998 |
Bold RJ, Termuhlen PM, McConkey DJ. Apoptosis, cancer and cancer therapy. Surgical Oncology. 6: 133-42. PMID 9576629 DOI: 10.1016/S0960-7404(97)00015-7 |
0.476 |
|
1998 |
Voehringer DW, McConkey DJ, McDonnell TJ, Brisbay S, Meyn RE. Bcl-2 expression causes redistribution of glutathione to the nucleus. Proceedings of the National Academy of Sciences of the United States of America. 95: 2956-60. PMID 9501197 DOI: 10.1073/Pnas.95.6.2956 |
0.432 |
|
1998 |
Chandra J, Niemer I, Gilbreath J, Kliche K, Andreeff M, Freireich EJ, Keating M, McConkey DJ. Proteasome Inhibitors Induce Apoptosis in Glucocorticoid-Resistant Chronic Lymphocytic Leukemic Lymphocytes Blood. 92: 4220-4229. DOI: 10.1182/Blood.V92.11.4220 |
0.456 |
|
1997 |
McConkey DJ, Orrenius S. The role of calcium in the regulation of apoptosis. Biochemical and Biophysical Research Communications. 239: 357-66. PMID 9344835 DOI: 10.1006/Bbrc.1997.7409 |
0.393 |
|
1997 |
Mirkovic N, Voehringer DW, Story MD, McConkey DJ, McDonnell TJ, Meyn RE. Resistance to radiation-induced apoptosis in Bcl-2-expressing cells is reversed by depleting cellular thiols Oncogene. 15: 1461-1470. PMID 9333022 DOI: 10.1038/Sj.Onc.1201310 |
0.458 |
|
1997 |
Xie K, Wang Y, Huang S, Xu L, Bielenberg D, Salas T, McConkey DJ, Jiang W, Fidler IJ. Nitric oxide-mediated apoptosis of K-1735 melanoma cells is associated with downregulation of Bcl-2. Oncogene. 15: 771-9. PMID 9266963 DOI: 10.1038/Sj.Onc.1201239 |
0.421 |
|
1997 |
McConkey DJ, Orrenius S. Signal transduction pathways in apoptosis. Stem Cells (Dayton, Ohio). 14: 619-31. PMID 8948020 DOI: 10.1002/Stem.140619 |
0.387 |
|
1997 |
Chandra J, Gilbreath J, Freireich EJ, Kliche K, Andreeff M, Keating M, McConkey DJ. Protease Activation Is Required for Glucocorticoid-Induced Apoptosis in Chronic Lymphocytic Leukemic Lymphocytes Blood. 90: 3673-3681. DOI: 10.1182/Blood.V90.9.3673 |
0.434 |
|
1996 |
Fernandez A, McConkey D, Ananthaswamy H. Resistance to tumor necrosis factor-induced apoptosis in mouse fibroblasts is a genetically dominant phenotype International Journal of Oncology. 8: 169-173. PMID 21544346 DOI: 10.3892/Ijo.8.1.169 |
0.446 |
|
1996 |
Gossett R, Kier AB, Schroeder F, McConkey D, Fadok V, Amoss MS. Cycloheximide-induced apoptosis in melanoma cells derived from regressing cutaneous tumours of Sinclair swine Journal of Comparative Pathology. 115: 353-372. PMID 9004078 DOI: 10.1016/S0021-9975(96)80071-5 |
0.465 |
|
1996 |
Xie K, Huang S, Wang Y, Beltran PJ, Juang SH, Dong Z, Reed JC, McDonnell TJ, McConkey DJ, Fidler IJ. Bcl-2 protects cells from cytokine-induced nitric-oxide-dependent apoptosis Cancer Immunology, Immunotherapy. 43: 109-115. PMID 8954145 DOI: 10.1007/S002620050310 |
0.476 |
|
1996 |
McConkey DJ. Calcium-dependent, interleukin 1-converting enzyme inhibitor-insensitive degradation of lamin B1 and DNA fragmentation in isolated thymocyte nuclei. The Journal of Biological Chemistry. 271: 22398-406. PMID 8798402 DOI: 10.1074/Jbc.271.37.22398 |
0.381 |
|
1996 |
McConkey DJ, Zhivotovsky B, Orrenius S. Apoptosis--molecular mechanisms and biomedical implications. Molecular Aspects of Medicine. 17: 1-110. PMID 8783196 DOI: 10.1016/0098-2997(95)00006-2 |
0.391 |
|
1996 |
Xue Y, Murdjeva M, Okret S, McConkey D, Kiuossis D, Jondal M. Inhibition of I-Ad-, but not Db-restricted peptide-induced thymic apoptosis by glucocorticoid receptor antagonist RU486 in T cell receptor transgenic mice. European Journal of Immunology. 26: 428-34. PMID 8617314 DOI: 10.1002/Eji.1830260224 |
0.338 |
|
1996 |
Warren A, Patel K, McConkey D, Palacios R. CD98: a type II transmembrane glycoprotein expressed from the beginning of primitive and definitive hematopoiesis may play a critical role in the development of hematopoietic cells Blood. 87: 3676-3687. DOI: 10.1182/Blood.V87.9.3676.Bloodjournal8793676 |
0.379 |
|
1996 |
McConkey DJ, Orrenius S. The role of calcium in the regulation of apoptosis Journal of Leukocyte Biology. 59: 775-783. DOI: 10.1002/Jlb.59.6.775 |
0.362 |
|
1996 |
Trent JC, McConkey DJ, Loughlin SM, Harbison MT, Fernandez A, Ananthaswamy HN. Ras signaling in tumor necrosis factor-induced apoptosis. The Embo Journal. 15: 4497-4505. DOI: 10.1002/J.1460-2075.1996.Tb00827.X |
0.389 |
|
1995 |
McConkey DJ, Jondal M, Orrenius S. The regulation of apoptosis in thymocytes. Biochemical Society Transactions. 22: 606-10. PMID 7821647 DOI: 10.1042/Bst0220606 |
0.374 |
|
1995 |
McConkey DJ, Nicotera P, Orrenius S. Signalling and chromatin fragmentation in thymocyte apoptosis. Immunological Reviews. 142: 343-63. PMID 7698800 DOI: 10.1111/J.1600-065X.1994.Tb00896.X |
0.326 |
|
1995 |
McConkey DJ, Orrenius S. Calcium and cyclosporin A in the regulation of apoptosis. Current Topics in Microbiology and Immunology. 200: 95-105. PMID 7634840 DOI: 10.1007/978-3-642-79437-7_7 |
0.326 |
|
1995 |
McConkey DJ, Fernandez A, Trent J, Ananthaswamy HN. Oncogene regulation of endonuclease activation in apoptosis. Cancer Letters. 94: 9-16. PMID 7621450 DOI: 10.1016/0304-3835(95)03835-K |
0.428 |
|
1993 |
McConkey DJ, Orrenius S, Okret S, Jondal M. Cyclic AMP potentiates glucocorticoid-induced endogenous endonuclease activation in thymocytes. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 7: 580-5. PMID 8386120 DOI: 10.1096/Fasebj.7.6.8386120 |
0.394 |
|
1993 |
Moingeon P, Rodewald H, McConkey D, Mildonian A, Awad K, Reinherz E. Generation of natural killer cells from both Fc gamma RII/III+ and Fc gamma RII/III- murine fetal liver progenitors Blood. 82: 1453-1462. DOI: 10.1182/Blood.V82.5.1453.1453 |
0.317 |
|
1991 |
Orrenius S, McConkey DJ, Nicotera P. Role of calcium in toxic and programmed cell death. Advances in Experimental Medicine and Biology. 283: 419-25. PMID 1648868 DOI: 10.1007/978-1-4684-5877-0_57 |
0.331 |
|
1990 |
McConkey DJ, Chow SC, Orrenius S, Jondal M. NK cell-induced cytotoxicity is dependent on a Ca2+ increase in the target. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 4: 2661-4. PMID 2347464 DOI: 10.1096/Fasebj.4.9.2347464 |
0.373 |
|
1990 |
McConkey DJ, Orrenius S, Jondal M. Cellular signalling in programmed cell death (apoptosis). Immunology Today. 11: 120-1. PMID 2187468 DOI: 10.1016/0167-5699(90)90048-E |
0.353 |
|
1990 |
McConkey DJ, Hartzell P, Orrenius S. Rapid turnover of endogenous endonuclease activity in thymocytes: effects of inhibitors of macromolecular synthesis. Archives of Biochemistry and Biophysics. 278: 284-7. PMID 2157360 DOI: 10.1016/0003-9861(90)90261-V |
0.382 |
|
1990 |
Perotti M, Toddei F, Mirabelli F, Vairetti M, Bellomo G, McConkey DJ, Orrenius S. Calcium-dependent DNA fragmentation in human synovial cells exposed to cold shock. Febs Letters. 259: 331-4. PMID 2152884 DOI: 10.1016/0014-5793(90)80040-P |
0.432 |
|
1989 |
Nicotera P, McConkey DJ, Dypbukt JM, Jones DP, Orrenius S. Ca2+-activated mechanisms in cell killing. Drug Metabolism Reviews. 20: 193-201. PMID 2680379 DOI: 10.3109/03602538909103536 |
0.321 |
|
1989 |
Orrenius S, McConkey DJ, Bellomo G, Nicotera P. Role of Ca2+ in toxic cell killing. Trends in Pharmacological Sciences. 10: 281-5. PMID 2672472 DOI: 10.1016/0165-6147(89)90029-1 |
0.343 |
|
1989 |
McConkey DJ, Orrenius S. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) kills glucocorticoid-sensitive thymocytes in vivo. Biochemical and Biophysical Research Communications. 160: 1003-8. PMID 2543382 DOI: 10.1016/S0006-291X(89)80101-9 |
0.319 |
|
1989 |
McConkey DJ, Nicotera P, Hartzell P, Bellomo G, Wyllie AH, Orrenius S. Glucocorticoids activate a suicide process in thymocytes through an elevation of cytosolic Ca2+ concentration. Archives of Biochemistry and Biophysics. 269: 365-70. PMID 2537063 DOI: 10.1016/0003-9861(89)90119-7 |
0.329 |
|
1989 |
McConkey DJ, Hartzell P, Nicotera P, Orrenius S. Calcium-activated DNA fragmentation kills immature thymocytes. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 3: 1843-9. PMID 2497041 DOI: 10.1096/Fasebj.3.7.2497041 |
0.363 |
|
1988 |
McConkey DJ, Hartzell P, Duddy SK, Håkansson H, Orrenius S. 2,3,7,8-Tetrachlorodibenzo-p-dioxin kills immature thymocytes by Ca2+-mediated endonuclease activation. Science (New York, N.Y.). 242: 256-9. PMID 3262923 DOI: 10.1126/Science.3262923 |
0.34 |
|
1988 |
McConkey DJ, Hartzell P, Nicotera P, Wyllie AH, Orrenius S. Stimulation of endogenous endonuclease activity in hepatocytes exposed to oxidative stress. Toxicology Letters. 42: 123-30. PMID 2841775 DOI: 10.1016/0378-4274(88)90069-0 |
0.352 |
|
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