Louis M. Staudt - Publications

Affiliations: 
The George Washington University, Washington, DC, United States 
 1988- National Cancer Institute, Rockville, MD, United States 
Area:
Oncology, Cell Biology
Website:
https://ccr.cancer.gov/Lymphoid-Malignancies-Branch/louis-m-staudt

367 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Scheich S, Chen J, Liu J, Schnutgen F, Enssle JC, Ceribelli M, Thomas CJ, Choi J, Morris V, Hsiao T, Nguyen H, Wang B, Bolomsky A, Phelan JD, Corcoran S, ... ... Staudt LM, et al. Targeting N-linked Glycosylation for the Therapy of Aggressive Lymphomas. Cancer Discovery. PMID 37141112 DOI: 10.1158/2159-8290.CD-22-1401  0.349
2021 Ishio T, Kumar S, Shimono J, Daenthanasanmak A, Dubois S, Lin Y, Bryant BR, Petrus MN, Bachy E, Huang DW, Yang Y, Green PL, Hasegawa H, Maeda M, Goto H, ... ... Staudt LM, et al. Genome-wide CRISPR screen identifies CDK6 as a therapeutic target in Adult T-cell leukemia/lymphoma. Blood. PMID 34818414 DOI: 10.1182/blood.2021012734  0.305
2021 Pighi C, Cheong TC, Compagno M, Patrucco E, Arigoni M, Olivero M, Wang Q, López C, Bernhart SH, Grande BM, Poggio T, Langellotto F, Bonello L, Dall'Olio R, Martínez-Martín S, ... ... Staudt LM, et al. Frequent mutations of FBXO11 highlight BCL6 as a therapeutic target in Burkitt lymphoma. Blood Advances. 5: 5239-5257. PMID 34625792 DOI: 10.1182/bloodadvances.2021005682  0.365
2021 Chiodin G, Allen JD, Bryant D, Rock P, Martino EA, Valle-Argos B, Duriez PJ, Watanabe Y, Henderson I, Blachly JS, McCann KJ, Strefford JC, Packham G, Geijtenbeek TB, Figdor C, ... ... Staudt LM, et al. Insertion of atypical glycans into the tumor antigen-binding site identifies DLBCLs with distinct origin and behavior. Blood. PMID 34424958 DOI: 10.1182/blood.2021012052  0.354
2021 Ruiz Cuevas MV, Hardy MP, Hollý J, Bonneil É, Durette C, Courcelles M, Lanoix J, Côté C, Staudt LM, Lemieux S, Thibault P, Perreault C, Yewdell JW. Most non-canonical proteins uniquely populate the proteome or immunopeptidome. Cell Reports. 34: 108815. PMID 33691108 DOI: 10.1016/j.celrep.2021.108815  0.47
2020 Wilke AC, Doebele C, Zindel A, Lee KS, Rieke SA, Ceribelli M, Comoglio F, Phelan JD, Wang JQ, Pikman Y, Jahn D, Häupl B, Schneider C, Scheich S, Tosto FA, ... ... Staudt LM, et al. SHMT2 inhibition disrupts the TCF3 transcriptional survival program in Burkitt lymphoma. Blood. PMID 34624079 DOI: 10.1182/blood.2021012081  0.31
2020 Dersh D, Phelan JD, Gumina ME, Wang B, Arbuckle JH, Holly J, Kishton RJ, Markowitz TE, Seedhom MO, Fridlyand N, Wright GW, Huang DW, Ceribelli M, Thomas CJ, Lack JB, ... ... Staudt LM, et al. Genome-wide Screens Identify Lineage- and Tumor-Specific Genes Modulating MHC-I- and MHC-II-Restricted Immunosurveillance of Human Lymphomas. Immunity. PMID 33271120 DOI: 10.1016/j.immuni.2020.11.002  0.55
2020 Fish K, Comoglio F, Shaffer AL, Ji Y, Pan KT, Scheich S, Oellerich A, Doebele C, Ikeda M, Schaller SJ, Nguyen H, Muppidi J, Wright GW, Urlaub H, Serve H, ... Staudt LM, et al. Rewiring of B cell receptor signaling by Epstein-Barr virus LMP2A. Proceedings of the National Academy of Sciences of the United States of America. PMID 33020271 DOI: 10.1073/pnas.2007946117  0.37
2020 Pittaluga S, Nicolae A, Wright GW, Melani C, Roschewski M, Steinberg S, Huang D, Staudt LM, Jaffe ES, Wilson WH. Gene Expression Profiling of Mediastinal Gray Zone Lymphoma and Its Relationship to Primary Mediastinal B-cell Lymphoma and Classical Hodgkin Lymphoma. Blood Cancer Discovery. 1: 155-161. PMID 32914098 DOI: 10.1158/2643-3230.BCD-20-0009  0.398
2020 Venturutti L, Teater M, Zhai A, Chadburn A, Babiker L, Kim D, Béguelin W, Lee TC, Kim Y, Chin CR, Yewdell WT, Raught B, Phillip JM, Jiang Y, Staudt LM, et al. TBL1XR1 Mutations Drive Extranodal Lymphoma by Inducing a Pro-tumorigenic Memory Fate. Cell. PMID 32619424 DOI: 10.1016/J.Cell.2020.05.049  0.452
2020 Wright GW, Huang DW, Phelan JD, Coulibaly ZA, Roulland S, Young RM, Wang JQ, Schmitz R, Morin RD, Tang J, Jiang A, Bagaev A, Plotnikova O, Kotlov N, Johnson CA, ... ... Staudt LM, et al. A Probabilistic Classification Tool for Genetic Subtypes of Diffuse Large B Cell Lymphoma with Therapeutic Implications. Cancer Cell. 37: 551-568.e14. PMID 32289277 DOI: 10.1016/J.Ccell.2020.03.015  0.376
2020 Phelan JD, Staudt LM. CRISPR-based technology to silence the expression of IncRNAs. Proceedings of the National Academy of Sciences of the United States of America. PMID 32245807 DOI: 10.1073/Pnas.2003702117  0.332
2020 Choi J, Phelan JD, Wright GW, Häupl B, Huang DW, Shaffer AL, Young RM, Wang Z, Zhao H, Yu X, Oellerich T, Staudt LM. Regulation of B cell receptor-dependent NF-κB signaling by the tumor suppressor KLHL14. Proceedings of the National Academy of Sciences of the United States of America. PMID 32127472 DOI: 10.1073/Pnas.1921187117  0.467
2020 Ennishi D, Healy S, Bashashati A, Saberi S, Hother C, Mottok A, Chan FC, Chong L, Abraham L, Kridel R, Boyle M, Meissner B, Aoki T, Takata K, Woolcock BW, ... ... Staudt LM, et al. TMEM30A loss-of-function mutations drive lymphomagenesis and confer therapeutically exploitable vulnerability in B-cell lymphoma. Nature Medicine. PMID 32094924 DOI: 10.1038/S41591-020-0757-Z  0.464
2019 Amador C, Greiner TC, Heavican TB, Smith LM, Galvis KT, Lone WG, Bouska A, D'amore F, Bjerregård Pedersen M, Pileri SA, Agostinelli C, Feldman AL, Rosenwald A, Ott G, Mottok A, ... ... Staudt LM, et al. Reproducing the Molecular Subclassification of Peripheral T-cell Lymphoma-NOS by Immunohistochemistry. Blood. PMID 31562134 DOI: 10.1182/Blood.2019000779  0.379
2019 Young RM, Phelan JD, Wilson WH, Staudt LM. Pathogenic B-cell receptor signaling in lymphoid malignancies: New insights to improve treatment. Immunological Reviews. 291: 190-213. PMID 31402495 DOI: 10.1111/Imr.12792  0.469
2019 Bartlett NL, Wilson WH, Jung SH, Hsi ED, Maurer MJ, Pederson LD, Polley MC, Pitcher BN, Cheson BD, Kahl BS, Friedberg JW, Staudt LM, Wagner-Johnston ND, Blum KA, Abramson JS, et al. Dose-Adjusted EPOCH-R Compared With R-CHOP as Frontline Therapy for Diffuse Large B-Cell Lymphoma: Clinical Outcomes of the Phase III Intergroup Trial Alliance/CALGB 50303. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO1801994. PMID 30939090 DOI: 10.1200/Jco.18.01994  0.327
2019 Younes A, Sehn LH, Johnson P, Zinzani PL, Hong X, Zhu J, Patti C, Belada D, Samoilova O, Suh C, Leppä S, Rai S, Turgut M, Jurczak W, Cheung MC, ... ... Staudt LM, et al. Randomized Phase III Trial of Ibrutinib and Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone in Non-Germinal Center B-Cell Diffuse Large B-Cell Lymphoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO1802403. PMID 30901302 DOI: 10.1200/Jco.18.02403  0.43
2019 Heavican TB, Bouska A, Yu J, Lone W, Amador C, Gong Q, Zhang W, Li Y, Dave BJ, Nairismägi ML, Greiner TC, Vose J, Weisenburger DD, Lachel C, Wang C, ... ... Staudt LM, et al. Genetic drivers of oncogenic pathways in molecular subgroups of peripheral T-cell lymphoma. Blood. PMID 30782609 DOI: 10.1182/Blood-2018-09-872549  0.44
2019 Wei J, Kishton RJ, Angel M, Conn CS, Dalla-Venezia N, Marcel V, Vincent A, Catez F, Ferré S, Ayadi L, Marchand V, Dersh D, Gibbs JS, Ivanov IP, Fridlyand N, ... ... Staudt LM, et al. Ribosomal Proteins Regulate MHC Class I Peptide Generation for Immunosurveillance. Molecular Cell. PMID 30712990 DOI: 10.1016/J.Molcel.2018.12.020  0.506
2019 Grande BM, Gerhard DS, Jiang A, Griner NB, Abramson JS, Alexander TB, Allen H, Ayers LW, Bethony JM, Bhatia K, Bowen J, Casper C, Choi JK, Culibrk L, Davidsen TM, ... ... Staudt LM, et al. Genome-wide discovery of somatic coding and non-coding mutations in pediatric endemic and sporadic Burkitt lymphoma. Blood. PMID 30617194 DOI: 10.1182/Blood-2018-09-871418  0.429
2019 Melani C, Lakhotia R, Pittaluga S, Miljkovic M, Portell C, Farah R, Juanitez A, Chou L, Steinberg S, Jaffe E, Staudt L, Roschewski M, Wilson W. PHASE 1B STUDY OF ViPOR (VENETOCLAX, IBRUTINIB, PREDNISONE, OBINUTUZUMAB, LENALIDOMIDE) IN RELAPSED/REFRACTORY B-CELL LYMPHOMA: SAFETY, EFFICACY AND MOLECULAR ANALYSIS Hematological Oncology. 37: 332-333. DOI: 10.1182/Blood-2019-125990  0.373
2019 Roschewski M, Izumi R, Hamdy A, Patel MR, Arkenau H, de Vos S, Reagan PM, Zinzani PL, Davies A, Pagel JM, Vose JM, Bitman B, Brock G, Clark E, Frigault MM, ... ... Staudt L, et al. PRISM: A Platform Protocol for the Treatment of Relapsed/Refractory Aggressive Non-Hodgkin Lymphoma Blood. 134: 2869-2869. DOI: 10.1182/Blood-2019-125939  0.324
2019 Choi J, Phelan JD, Young RM, Oellerich T, Huang DW, Shaffer AL, Staudt L. KLHL14 Is a Tumor Suppressor in Diffuse Large B-Cell Lymphoma Blood. 134: 2766-2766. DOI: 10.1182/Blood-2019-125137  0.508
2019 Ishio T, Shimono J, Kumar S, Lin Y, Bachy E, Petrus MN, Yang Y, Maeda M, Goto H, Hashino S, Teshima T, Waldmann TA, Staudt L, Nakagawa M. Genome-Wide CRISPR Library Screening Identifies CDK6 As Genetic Vulnerability in Adult T-Cell Leukemia/Lymphoma Blood. 134: 3781-3781. DOI: 10.1182/Blood-2019-124670  0.474
2019 Johnson P, Balasubramanian S, Hodkinson B, Schaffer M, Parisi L, Shreeve SM, Sun S, Vermeulen J, Sehn LH, Staudt L, Younes A, Wilson W. Clinical Impact of Ibrutinib with R-CHOP in Untreated Non-GCB DLBCL Co-Expressing BCL2 and MYC Genes in the Phase 3 Phoenix Trial Blood. 134: 354-354. DOI: 10.1182/Blood-2019-124443  0.332
2019 Roschewski M, Melani C, Dunleavy K, Holdhoff M, Swinnen LJ, Glantz M, Portell CA, Svoboda J, Farah R, Lionakis MS, Staudt L, Wilson W. Reponse-Adapted Study of Ibrutinib with Temozolomide, Etoposide, Doxil, Dexamethasone, and Rituximab (TEDDI-R) in Aggressive B-Cell Lymphomas with Secondary Involvement of the CNS Blood. 134: 2875-2875. DOI: 10.1182/Blood-2019-123552  0.369
2019 Balasubramanian S, Wang S, Major C, Hodkinson B, Schaffer M, Sehn L, Johnson P, Zinzani P, Carey J, Liu G, Loefgren C, Shreeve M, Sun S, Zhuang S, Vermeulen J, ... Staudt L, et al. CONCORDANCE BETWEEN IMMUNOHISTOCHEMISTRY AND GENE EXPRESSION PROFILING SUBTYPING FOR DIFFUSE LARGE B-CELL LYMPHOMA IN THE PHASE 3 PHOENIX TRIAL Hematological Oncology. 37: 140-142. DOI: 10.1002/Hon.99_2629  0.436
2018 Dadashian EL, McAuley EM, Liu D, Shaffer AL, Young RM, Iyer JR, Kruhlak MJ, Staudt LM, Wiestner A, Herman SEM. TLR signaling is activated in lymph-node resident CLL cells and is only partially inhibited by ibrutinib. Cancer Research. PMID 30498085 DOI: 10.1158/0008-5472.Can-18-0781  0.391
2018 Corces MR, Granja JM, Shams S, Louie BH, Seoane JA, Zhou W, Silva TC, Groeneveld C, Wong CK, Cho SW, Satpathy AT, Mumbach MR, Hoadley KA, Robertson AG, Sheffield NC, ... ... Staudt LM, et al. The chromatin accessibility landscape of primary human cancers. Science (New York, N.Y.). 362. PMID 30361341 DOI: 10.1126/Science.Aav1898  0.481
2018 Mottok A, Wright G, Rosenwald A, Ott G, Ramsower C, Campo E, Braziel RM, Delabie J, Weisenburger DD, Song JY, Chan WC, Cook JR, Fu K, Greiner T, Smeland E, ... ... Staudt LM, et al. Molecular classification of primary mediastinal large B-cell lymphoma using routinely available tissue specimens. Blood. PMID 30257882 DOI: 10.1182/Blood-2018-05-851154  0.43
2018 Wright GW, Wilson WH, Staudt LM. Genetics of Diffuse Large B-Cell Lymphoma. The New England Journal of Medicine. 379: 493-494. PMID 30067933 DOI: 10.1056/Nejmc1806191  0.396
2018 Nakagawa M, Shaffer AL, Ceribelli M, Zhang M, Wright G, Huang DW, Xiao W, Powell J, Petrus MN, Yang Y, Phelan JD, Kohlhammer H, Dubois SP, Yoo HM, Bachy E, ... ... Staudt LM, et al. Targeting the HTLV-I-Regulated BATF3/IRF4 Transcriptional Network in Adult T Cell Leukemia/Lymphoma. Cancer Cell. PMID 30057145 DOI: 10.1182/Blood.V130.Suppl_1.731.731  0.437
2018 Phelan JD, Young RM, Webster DE, Roulland S, Wright GW, Kasbekar M, Shaffer AL, Ceribelli M, Wang JQ, Schmitz R, Nakagawa M, Bachy E, Huang DW, Ji Y, Chen L, ... ... Staudt LM, et al. A multiprotein supercomplex controlling oncogenic signalling in lymphoma. Nature. PMID 29925955 DOI: 10.1038/S41586-018-0290-0  0.471
2018 Clot G, Jares P, Giné E, Navarro A, Royo C, Pinyol M, Martín-Garcia D, Demajo S, Espinet B, Salar A, Ferrer A, Muntañola A, Aymerich M, Rauert-Wunderlich H, Jaffe ES, ... ... Staudt LM, et al. A new molecular assay and genomic complexity predict outcome in conventional and leukemic non-nodal mantle cell lymphoma. Blood. PMID 29769262 DOI: 10.1182/Blood-2018-03-838136  0.371
2018 Schmitz R, Wright GW, Huang DW, Johnson CA, Phelan JD, Wang JQ, Roulland S, Kasbekar M, Young RM, Shaffer AL, Hodson DJ, Xiao W, Yu X, Yang Y, Zhao H, ... ... Staudt LM, et al. Genetics and Pathogenesis of Diffuse Large B-Cell Lymphoma. The New England Journal of Medicine. 378: 1396-1407. PMID 29641966 DOI: 10.1056/Nejmoa1801445  0.469
2017 Pongas GN, Annunziata CM, Staudt LM. PI3Kδ inhibition causes feedback activation of PI3Kα in the ABC subtype of diffuse large B-cell lymphoma. Oncotarget. 8: 81794-81802. PMID 29137222 DOI: 10.18632/Oncotarget.20864  0.459
2017 Karube K, Enjuanes A, Dlouhy I, Jares P, Martin-Garcia D, Nadeu F, Ordóñez GR, Rovira J, Clot G, Royo C, Navarro A, Gonzalez-Farre B, Vaghefi A, Castellano G, Rubio-Perez C, ... ... Staudt LM, et al. Integrating genomic alterations in diffuse large B-cell lymphoma identifies new relevant pathways and potential therapeutic targets. Leukemia. PMID 28804123 DOI: 10.1182/Blood.V128.22.152.152  0.463
2017 Bouska A, Bi C, Lone W, Zhang W, Kedwaii A, Heavican T, Lachel CM, Yu J, Ferro R, Eldorghamy N, Greiner TC, Vose J, Weisenburger DD, Gascoyne RD, Rosenwald A, ... ... Staudt LM, et al. Adult High Grade B-cell Lymphoma with Burkitt Lymphoma Signature: Genomic features and Potential Therapeutic Targets. Blood. PMID 28801451 DOI: 10.1182/Blood-2017-02-767335  0.444
2017 Jais JP, Molina TJ, Ruminy P, Gentien D, Reyes C, Scott DW, Rimsza LM, Wright G, Gascoyne RD, Staudt LM, Haioun C, Tilly H, Gaulard P, Salles GA, Jardin F, et al. Reliable subtype classification of diffuse large B-Cell lymphoma samples from GELA LNH2003 trials using the Lymph2Cx gene expression assay. Haematologica. PMID 28679653 DOI: 10.3324/Haematol.2017.166827  0.436
2017 Lionakis MS, Dunleavy K, Roschewski M, Widemann BC, Butman JA, Schmitz R, Yang Y, Cole DE, Melani C, Higham CS, Desai JV, Ceribelli M, Chen L, Thomas CJ, Little RF, ... ... Staudt LM, et al. Inhibition of B Cell Receptor Signaling by Ibrutinib in Primary CNS Lymphoma. Cancer Cell. PMID 28552327 DOI: 10.1016/J.Ccell.2017.04.012  0.39
2017 Souroullas GP, Fedoriw Y, Staudt LM, Sharpless NE. Lkb1 deletion in murine B lymphocytes promotes cell death and cancer. Experimental Hematology. PMID 28435024 DOI: 10.1016/J.Exphem.2017.04.005  0.457
2017 Czuczman MS, Trněný M, Davies A, Rule SA, Linton K, Wagner-Johnston N, Gascoyne RD, Slack G, Brousset P, Eberhard DA, Hernandez-Ilizaliturri FJ, Salles G, Witzig TE, Zinzani PL, Wright GW, ... Staudt LM, et al. A Phase 2/3 Multicenter, Randomized, Open-Label Study of Lenalidomide vs Investigator's Choice in Patients with Relapsed or Refractory Diffuse Large B-Cell Lymphoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28381416 DOI: 10.1158/1078-0432.Ccr-16-2818  0.36
2017 Jerkeman M, Hallek M, Dreyling M, Thieblemont C, Kimby E, Staudt L. Targeting of B-cell receptor signalling in B-cell malignancies. Journal of Internal Medicine. 282: 415-428. PMID 28295729 DOI: 10.1111/Joim.12600  0.407
2017 Scott DW, Abrisqueta P, Wright GW, Slack GW, Mottok A, Villa D, Jares P, Rauert-Wunderlich H, Royo C, Clot G, Pinyol M, Boyle M, Chan FC, Braziel RM, Chan WC, ... ... Staudt LM, et al. New Molecular Assay for the Proliferation Signature in Mantle Cell Lymphoma Applicable to Formalin-Fixed Paraffin-Embedded Biopsies. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2016707901. PMID 28291392 DOI: 10.1200/Jco.2016.70.7901  0.394
2017 Grande BM, Gerhard DS, Griner NB, Casper C, Namirembe C, Omoding A, Orem J, Mbulaiteye SM, Mullighan CG, Sandlund JT, Alexander T, Choi JK, Abramson JS, Gross TG, Noy A, ... ... Staudt LM, et al. Burkitt Lymphoma Genome Sequencing Project (BLGSP): Integrative Genomic and Transcriptomic Characterization of Burkitt Lymphoma Blood. 130: 39-39. DOI: 10.1182/Blood.V130.Suppl_1.39.39  0.415
2017 Webster DE, Phelan JD, Kasbekar M, Shaffer AL, Staudt LM. Abstract PR13: CRISPRi screening with targeted therapeutics classifies functional long non-coding RNAs in DLBCL Molecular Cancer Therapeutics. 16. DOI: 10.1158/1538-8514.Synthleth-Pr13  0.353
2017 Mottok A, Wright G, Rosenwald A, Ott G, Ramsower C, Campo E, Braziel R, Delabie J, Weisenburger D, Song J, Chan J, Cook J, Fu K, Greiner T, Smeland E, ... ... Staudt L, et al. MOLECULAR CLASSIFICATION OF PRIMARY MEDIASTINAL LARGE B CELL LYMPHOMA USING FORMALIN-FIXED, PARAFFIN-EMBEDDED TISSUE SPECIMENS - AN LLMPP PROJECT Hematological Oncology. 35: 59-60. DOI: 10.1002/Hon.2437_46  0.367
2017 Young R, Phelan J, Webster D, Roulland S, Wright G, Huang D, Schmitz R, Staudt L. CRISPR-CAS9 GENETIC SCREENS UNCOVER A B CELL RECEPTOR-MYD88 SUPERPATHWAY IN DIFFUSE LARGE B CELL LYMPHOMA Hematological Oncology. 35: 25-25. DOI: 10.1002/Hon.2437_4  0.42
2016 Walter R, Pan KT, Doebele C, Comoglio F, Tomska K, Bohnenberger H, Young RM, Jacobs L, Keller U, Bönig H, Engelke M, Rosenwald A, Urlaub H, Staudt LM, Serve H, et al. HSP90 promotes Burkitt lymphoma cell survival by maintaining tonic B cell receptor signaling. Blood. PMID 28064214 DOI: 10.1182/Blood-2016-06-721423  0.452
2016 Grajkowska LT, Ceribelli M, Lau CM, Warren ME, Tiniakou I, Nakandakari Higa S, Bunin A, Haecker H, Mirny LA, Staudt LM, Reizis B. Isoform-Specific Expression and Feedback Regulation of E Protein TCF4 Control Dendritic Cell Lineage Specification. Immunity. PMID 27986456 DOI: 10.1016/J.Immuni.2016.11.006  0.36
2016 Ceribelli M, Hou ZE, Kelly PN, Huang DW, Wright G, Ganapathi K, Evbuomwan MO, Pittaluga S, Shaffer AL, Marcucci G, Forman SJ, Xiao W, Guha R, Zhang X, Ferrer M, ... ... Staudt LM, et al. A Druggable TCF4- and BRD4-Dependent Transcriptional Network Sustains Malignancy in Blastic Plasmacytoid Dendritic Cell Neoplasm. Cancer Cell. 30: 764-778. PMID 27846392 DOI: 10.1182/Blood.V128.22.1513.1513  0.391
2016 Rui L, Drennan AC, Ceribelli M, Zhu F, Wright GW, Huang DW, Xiao W, Li Y, Grindle KM, Lu L, Hodson DJ, Shaffer AL, Zhao H, Xu W, Yang Y, ... Staudt LM, et al. Epigenetic gene regulation by Janus kinase 1 in diffuse large B-cell lymphoma. Proceedings of the National Academy of Sciences of the United States of America. PMID 27799566 DOI: 10.1073/Pnas.1610970113  0.48
2016 Bouska A, Zhang W, Gong Q, Iqbal J, Scuto A, Vose J, Ludvigsen M, Fu K, Weisenburger DD, Greiner TC, Gascoyne RD, Rosenwald A, Ott G, Campo E, Rimsza LM, ... ... Staudt LM, et al. Combined copy number and mutation analysis identifies oncogenic pathways associated with transformation of follicular lymphoma. Leukemia. PMID 27389057 DOI: 10.1038/Leu.2016.175  0.42
2016 Yang Y, Kelly P, Shaffer AL, Schmitz R, Yoo HM, Liu X, Huang da W, Webster D, Young RM, Nakagawa M, Ceribelli M, Wright GW, Yang Y, Zhao H, Yu X, ... ... Staudt LM, et al. Targeting Non-proteolytic Protein Ubiquitination for the Treatment of Diffuse Large B Cell Lymphoma. Cancer Cell. 29: 494-507. PMID 27070702 DOI: 10.1016/J.Ccell.2016.03.006  0.444
2016 Knittel G, Liedgens P, Korovkina D, Seeger JM, Al-Baldawi Y, Al-Maarri M, Fritz C, Vlantis K, Bezhanova S, Scheel AH, Wolz OO, Reimann M, Möller P, López C, Schlesner M, ... ... Staudt LM, et al. B cell-specific conditional expression of Myd88p.L252P leads to the development of diffuse large B cell lymphoma in mice. Blood. PMID 27048211 DOI: 10.1182/Blood-2015-11-684183  0.457
2016 Hodson DJ, Shaffer AL, Xiao W, Wright GW, Schmitz R, Phelan JD, Yang Y, Webster DE, Rui L, Kohlhammer H, Nakagawa M, Waldmann TA, Staudt LM. Regulation of normal B-cell differentiation and malignant B-cell survival by OCT2. Proceedings of the National Academy of Sciences of the United States of America. PMID 26993806 DOI: 10.1073/Pnas.1600557113  0.522
2016 Dekker JD, Park D, Shaffer AL, Kohlhammer H, Deng W, Lee BK, Ippolito GC, Georgiou G, Iyer VR, Staudt LM, Tucker HO. Subtype-specific addiction of the activated B-cell subset of diffuse large B-cell lymphoma to FOXP1. Proceedings of the National Academy of Sciences of the United States of America. PMID 26787899 DOI: 10.1073/Pnas.1524677113  0.538
2016 Leroy K, Jais J, Ruminy P, Gentien D, Reyes C, Scott DW, Rimsza LM, Wright G, Gascoyne RD, Staudt LM, Haioun C, Tilly H, Gaulard P, Salles GA, Molina T, et al. Classification of diffuse large b-cell lymphoma (DLBCL) FFPE samples of the GELA LNH2003 program, using Lymph2Cx assay on the nCounter analysis system. Journal of Clinical Oncology. 34: 7547-7547. DOI: 10.1200/Jco.2016.34.15_Suppl.7547  0.39
2016 Scott DW, Abrisqueta P, Wright G, Jares P, Slack GW, Mottok A, Royo C, Clot G, Pinyol M, Boyle M, Villa D, Steidl C, Connors JM, Rosenwald A, Staudt LM, et al. Prognostic significance of the proliferation signature in mantle cell lymphoma measured using digital gene expression in formalin-fixed paraffin-embedded tissue biopsies. Journal of Clinical Oncology. 34: 7510-7510. DOI: 10.1200/Jco.2016.34.15_Suppl.7510  0.459
2016 Wilson WH, sin-Ho J, Pitcher BN, Hsi ED, Friedberg J, Cheson B, Bartlett NL, Smith S, Johnston NW, Kahl BS, Staudt LM, Blum K, Abramson J, Press OW, Fisher RI, et al. Phase III Randomized Study of R-CHOP Versus DA-EPOCH-R and Molecular Analysis of Untreated Diffuse Large B-Cell Lymphoma: CALGB/Alliance 50303 Blood. 128: 469-469. DOI: 10.1182/Blood.V128.22.469.469  0.362
2016 Yoo HM, Schmitz R, Yu X, Huang DW, Phelan JD, Webster DE, Staudt LM. Genome-Scale ORF Screen for Mediators of NF-κb Activation in DLBCL Blood. 128: 4102-4102. DOI: 10.1182/Blood.V128.22.4102.4102  0.44
2016 Heavican TB, Yu J, Bouska A, Greiner TC, Lachel CM, Wang C, Dave BJ, Amador CC, Fu K, Vose JM, Weisenburger DD, Gascoyne RD, Hartmann S, Pedersen MB, Wilcox R, ... ... Staudt L, et al. Molecular Subgroups of Peripheral T-Cell Lymphoma Evolve By Distinct Genetic Pathways Blood. 128: 4096-4096. DOI: 10.1182/Blood.V128.22.4096.4096  0.365
2016 Bouska A, Bi C, Lone W, Zhang W, Kedwaii A, Heavican TB, Lachel CM, Yu J, Fu K, Ferro RA, Eldorghamy N, Greiner TC, Vose JM, Weisenburger DD, Gascoyne RD, ... ... Staudt LM, et al. Comprehensive Genomic Analysis of Adult Burkitt Lymphoma Identifies the B-Cell Receptor Signaling Pathway As a Potential Therapeutic Target Blood. 128: 4095-4095. DOI: 10.1182/Blood.V128.22.4095.4095  0.394
2016 Gerhard DS, Grande B, Griner N, Casper C, Gerdts SE, Omoding A, Orem J, Mbulaiteye SM, Ogwang MD, Reynolds SJ, Bhatia K, Ayers L, Choi JK, Mullighan CG, Sandlund JT, ... ... Staudt LM, et al. Burkitt Lymphoma Genome Sequencing Project (BLGSP): Introduction Blood. 128: 1760-1760. DOI: 10.1182/Blood.V128.22.1760.1760  0.386
2015 Rohr J, Guo S, Huo J, Bouska A, Lachel C, Li Y, Simone PD, Zhang W, Gong Q, Wang C, Cannon A, Heavican T, Mottok A, Hung S, Rosenwald A, ... ... Staudt LM, et al. Recurrent activating mutations of CD28 in peripheral T-cell lymphomas. Leukemia. PMID 26719098 DOI: 10.1038/Leu.2015.357  0.345
2015 Kelly PN, Romero DL, Yang Y, Shaffer AL, Chaudhary D, Robinson S, Miao W, Rui L, Westlin WF, Kapeller R, Staudt LM. Selective interleukin-1 receptor-associated kinase 4 inhibitors for the treatment of autoimmune disorders and lymphoid malignancy. The Journal of Experimental Medicine. PMID 26621451 DOI: 10.1084/Jem.20151074  0.387
2015 Young RM, Wu T, Schmitz R, Dawood M, Xiao W, Phelan JD, Xu W, Menard L, Meffre E, Chan WC, Jaffe ES, Gascoyne RD, Campo E, Rosenwald A, Ott G, ... ... Staudt LM, et al. Survival of human lymphoma cells requires B-cell receptor engagement by self-antigens. Proceedings of the National Academy of Sciences of the United States of America. 112: 13447-54. PMID 26483459 DOI: 10.1073/Pnas.1514944112  0.451
2015 Kendrick S, Tus K, Wright G, Jaffe ES, Rosenwald A, Campo E, Chan WC, Connors JM, Braziel RM, Ott G, Delabie J, Cook JR, Weisenburger DD, Greiner TC, Fu K, ... Staudt LM, et al. Diffuse large B-cell lymphoma cell-of-origin classification using the Lymph2Cx assay in the context of BCL2 and MYC expression status. Leukemia & Lymphoma. 1-4. PMID 26437080 DOI: 10.3109/10428194.2015.1072767  0.462
2015 Hathcock KS, Padilla-Nash HM, Camps J, Shin DM, Triner D, Shaffer AL, Maul RW, Steinberg SM, Gearhart PJ, Staudt LM, Morse HC, Ried T, Hodes RJ. ATM deficiency in absence of T cells promotes development of NF-kB-dependent murine B cell lymphomas that resemble human ABC DLBCL. Blood. PMID 26400962 DOI: 10.1182/Blood-2015-06-654749  0.48
2015 Wang C, McKeithan TW, Gong Q, Zhang W, Bouska A, Rosenwald A, Gascoyne RD, Wu X, Wang J, Muhammad Z, Jiang B, Rohr J, Cannon A, Steidl C, Fu K, ... ... Staudt LM, et al. IDH2R172 mutations define a unique subgroup of patients with angioimmunoblastic T-cell lymphoma. Blood. PMID 26268241 DOI: 10.1182/Blood-2015-05-644591  0.426
2015 Scott DW, Mottok A, Ennishi D, Wright GW, Farinha P, Ben-Neriah S, Kridel R, Barry GS, Hother C, Abrisqueta P, Boyle M, Meissner B, Telenius A, Savage KJ, Sehn LH, ... ... Staudt LM, et al. Prognostic Significance of Diffuse Large B-Cell Lymphoma Cell of Origin Determined by Digital Gene Expression in Formalin-Fixed Paraffin-Embedded Tissue Biopsies. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 33: 2848-56. PMID 26240231 DOI: 10.1200/Jco.2014.60.2383  0.469
2015 Bunin A, Sisirak V, Ghosh HS, Grajkowska LT, Hou ZE, Miron M, Yang C, Ceribelli M, Uetani N, Chaperot L, Plumas J, Hendriks W, Tremblay ML, Häcker H, Staudt LM, et al. Protein Tyrosine Phosphatase PTPRS Is an Inhibitory Receptor on Human and Murine Plasmacytoid Dendritic Cells. Immunity. PMID 26231120 DOI: 10.1016/J.Immuni.2015.07.009  0.325
2015 Wilson WH, Young RM, Schmitz R, Yang Y, Pittaluga S, Wright G, Lih CJ, Williams PM, Shaffer AL, Gerecitano J, de Vos S, Goy A, Kenkre VP, Barr PM, Blum KA, ... ... Staudt LM, et al. Targeting B cell receptor signaling with ibrutinib in diffuse large B cell lymphoma. Nature Medicine. PMID 26193343 DOI: 10.1038/Nm.3884  0.459
2015 Yuan J, Wright G, Rosenwald A, Steidl C, Gascoyne RD, Connors JM, Mottok A, Weisenburger DD, Greiner TC, Fu K, Smith L, Rimsza LM, Jaffe ES, Campo E, Martinez A, ... ... Staudt LM, et al. Identification of Primary Mediastinal Large B-cell Lymphoma at Nonmediastinal Sites by Gene Expression Profiling. The American Journal of Surgical Pathology. PMID 26135560 DOI: 10.1097/Pas.0000000000000473  0.372
2015 Malecka A, Tierens A, Østlie I, Schmitz R, Trøen G, Spetalen S, Staudt LM, Smeland E, Holte H, Delabie J. Primary diffuse large B-cell lymphoma associated with clonally-related monoclonal B lymphocytosis indicates a common precursor cell. Haematologica. 100: e415-8. PMID 26001788 DOI: 10.3324/Haematol.2015.126656  0.41
2015 Roschewski M, Dunleavy K, Pittaluga S, Moorhead M, Pepin F, Kong K, Shovlin M, Jaffe ES, Staudt LM, Lai C, Steinberg SM, Chen CC, Zheng J, Willis TD, Faham M, et al. Circulating tumour DNA and CT monitoring in patients with untreated diffuse large B-cell lymphoma: a correlative biomarker study. The Lancet. Oncology. 16: 541-9. PMID 25842160 DOI: 10.1016/S1470-2045(15)70106-3  0.395
2015 Weinstock DM, Dalla-Favera R, Gascoyne RD, Leonard JP, Levy R, Lossos IS, Melnick AM, Nowakowski GS, Press OW, Savage KJ, Shipp MA, Staudt LM. A roadmap for discovery and translation in lymphoma. Blood. 125: 2175-7. PMID 25814490 DOI: 10.1182/Blood-2015-01-623777  0.358
2015 Young RM, Shaffer AL, Phelan JD, Staudt LM. B-cell receptor signaling in diffuse large B-cell lymphoma. Seminars in Hematology. 52: 77-85. PMID 25805587 DOI: 10.1053/J.Seminhematol.2015.01.008  0.485
2015 Yang Y, Staudt LM. Protein ubiquitination in lymphoid malignancies. Immunological Reviews. 263: 240-56. PMID 25510281 DOI: 10.1111/Imr.12247  0.381
2015 Iqbal J, Shen Y, Huang X, Liu Y, Wake L, Liu C, Deffenbacher K, Lachel CM, Wang C, Rohr J, Guo S, Smith LM, Wright G, Bhagavathi S, Dybkaer K, ... ... Staudt LM, et al. Global microRNA expression profiling uncovers molecular markers for classification and prognosis in aggressive B-cell lymphoma. Blood. 125: 1137-45. PMID 25498913 DOI: 10.1182/Blood-2014-04-566778  0.42
2015 Wang X, Wang H, Bi C, Zhang X, Huang X, Zhang X, Iqbal J, Wright GW, Staudt LM, Chan WC, McKeithan TW, Wang P, Zhang H, Fu K. Microrna-17~92 Cluster Upregulates NF-KB Activity Via Suppressing Multiple NF-KB Negative Regulators Mediating Ubiquitination Blood. 126: 3638-3638. DOI: 10.1182/Blood.V126.23.3638.3638  0.338
2015 Staudt LM. Abstract IA09: Therapy of lymphoma inspired by functional and structural genomics Cancer Research. 75. DOI: 10.1158/1538-7445.Transcagen-Ia09  0.444
2015 Nakagawa M, Schmitz R, Xiao W, Goldman CK, Xu W, Yang Y, Yu X, Waldmann TA, Staudt LM. Abstract 3936: Frequent gain-of-function CCR4 mutations in adult T-cell leukemia/lymphoma (ATLL) Cancer Research. 75: 3936-3936. DOI: 10.1158/1538-7445.Am2015-3936  0.409
2015 Wang X, Wang H, Bi C, Zhang X, Huang X, Zhang X, Iqbal J, Wright G, Staudt L, Chan W, McKeithan T, Wang P, Zhang H, Fu K. 296P miR-17 ∼ 92 activates the canonical NF-&kgr;B signaling by targeting TNFAIP3, CYLD and Rnf11 in ABC-DLBCL lymphoma Annals of Oncology. 26: ix85. DOI: 10.1093/Annonc/Mdv526.12  0.322
2014 Nakagawa M, Schmitz R, Xiao W, Goldman CK, Xu W, Yang Y, Yu X, Waldmann TA, Staudt LM. Gain-of-function CCR4 mutations in adult T cell leukemia/lymphoma. The Journal of Experimental Medicine. 211: 2497-505. PMID 25488980 DOI: 10.1084/Jem.20140987  0.372
2014 Qian J, Wang Q, Dose M, Pruett N, Kieffer-Kwon KR, Resch W, Liang G, Tang Z, Mathé E, Benner C, Dubois W, Nelson S, Vian L, Oliveira TY, Jankovic M, ... ... Staudt L, et al. B cell super-enhancers and regulatory clusters recruit AID tumorigenic activity. Cell. 159: 1524-37. PMID 25483777 DOI: 10.1016/J.Cell.2014.11.013  0.439
2014 Muppidi JR, Schmitz R, Green JA, Xiao W, Larsen AB, Braun SE, An J, Xu Y, Rosenwald A, Ott G, Gascoyne RD, Rimsza LM, Campo E, Jaffe ES, Delabie J, ... ... Staudt LM, et al. Loss of signalling via Gα13 in germinal centre B-cell-derived lymphoma. Nature. 516: 254-8. PMID 25274307 DOI: 10.1038/Nature13765  0.324
2014 Kendrick SL, Redd L, Muranyi A, Henricksen LA, Stanislaw S, Smith LM, Perry AM, Fu K, Weisenburger DD, Rosenwald A, Ott G, Gascoyne RD, Jaffe ES, Campo E, Delabie J, ... ... Staudt LM, et al. BCL2 antibodies targeted at different epitopes detect varying levels of protein expression and correlate with frequent gene amplification in diffuse large B-cell lymphoma. Human Pathology. 45: 2144-53. PMID 25090918 DOI: 10.1016/J.Humpath.2014.06.005  0.448
2014 Ceribelli M, Kelly PN, Shaffer AL, Wright GW, Xiao W, Yang Y, Mathews Griner LA, Guha R, Shinn P, Keller JM, Liu D, Patel PR, Ferrer M, Joshi S, Nerle S, ... ... Staudt LM, et al. Blockade of oncogenic IκB kinase activity in diffuse large B-cell lymphoma by bromodomain and extraterminal domain protein inhibitors. Proceedings of the National Academy of Sciences of the United States of America. 111: 11365-70. PMID 25049379 DOI: 10.1073/Pnas.1411701111  0.455
2014 Wilson WH, Pittaluga S, Nicolae A, Camphausen K, Shovlin M, Steinberg SM, Roschewski M, Staudt LM, Jaffe ES, Dunleavy K. A prospective study of mediastinal gray-zone lymphoma. Blood. 124: 1563-9. PMID 25024303 DOI: 10.1182/Blood-2014-03-564906  0.393
2014 Ghosh HS, Ceribelli M, Matos I, Lazarovici A, Bussemaker HJ, Lasorella A, Hiebert SW, Liu K, Staudt LM, Reizis B. ETO family protein Mtg16 regulates the balance of dendritic cell subsets by repressing Id2. The Journal of Experimental Medicine. 211: 1623-35. PMID 24980046 DOI: 10.1084/Jem.20132121  0.331
2014 Iqbal J, Wright G, Wang C, Rosenwald A, Gascoyne RD, Weisenburger DD, Greiner TC, Smith L, Guo S, Wilcox RA, Teh BT, Lim ST, Tan SY, Rimsza LM, Jaffe ES, ... ... Staudt LM, et al. Gene expression signatures delineate biological and prognostic subgroups in peripheral T-cell lymphoma. Blood. 123: 2915-23. PMID 24632715 DOI: 10.1182/Blood-2013-11-536359  0.455
2014 Ippolito GC, Dekker JD, Wang YH, Lee BK, Shaffer AL, Lin J, Wall JK, Lee BS, Staudt LM, Liu YJ, Iyer VR, Tucker HO. Dendritic cell fate is determined by BCL11A. Proceedings of the National Academy of Sciences of the United States of America. 111: E998-1006. PMID 24591644 DOI: 10.1073/Pnas.1319228111  0.422
2014 Schmitz R, Ceribelli M, Pittaluga S, Wright G, Staudt LM. Oncogenic mechanisms in Burkitt lymphoma. Cold Spring Harbor Perspectives in Medicine. 4. PMID 24492847 DOI: 10.1101/Cshperspect.A014282  0.519
2014 Yang Y, Schmitz R, Mitala J, Whiting A, Xiao W, Ceribelli M, Wright GW, Zhao H, Yang Y, Xu W, Rosenwald A, Ott G, Gascoyne RD, Connors JM, Rimsza LM, ... ... Staudt LM, et al. Essential role of the linear ubiquitin chain assembly complex in lymphoma revealed by rare germline polymorphisms. Cancer Discovery. 4: 480-93. PMID 24491438 DOI: 10.1158/2159-8290.Cd-13-0915  0.406
2014 Mathews Griner LA, Guha R, Shinn P, Young RM, Keller JM, Liu D, Goldlust IS, Yasgar A, McKnight C, Boxer MB, Duveau DY, Jiang JK, Michael S, Mierzwa T, Huang W, ... ... Staudt LM, et al. High-throughput combinatorial screening identifies drugs that cooperate with ibrutinib to kill activated B-cell-like diffuse large B-cell lymphoma cells. Proceedings of the National Academy of Sciences of the United States of America. 111: 2349-54. PMID 24469833 DOI: 10.1073/Pnas.1311846111  0.416
2014 Scott DW, Wright GW, Williams PM, Lih CJ, Walsh W, Jaffe ES, Rosenwald A, Campo E, Chan WC, Connors JM, Smeland EB, Mottok A, Braziel RM, Ott G, Delabie J, ... ... Staudt LM, et al. Determining cell-of-origin subtypes of diffuse large B-cell lymphoma using gene expression in formalin-fixed paraffin-embedded tissue. Blood. 123: 1214-7. PMID 24398326 DOI: 10.1182/Blood-2013-11-536433  0.477
2014 Roschewski M, Staudt LM, Wilson WH. Diffuse large B-cell lymphoma-treatment approaches in the molecular era. Nature Reviews. Clinical Oncology. 11: 12-23. PMID 24217204 DOI: 10.1038/Nrclinonc.2013.197  0.408
2014 Bouska A, McKeithan TW, Deffenbacher KE, Lachel C, Wright GW, Iqbal J, Smith LM, Zhang W, Kucuk C, Rinaldi A, Bertoni F, Fitzgibbon J, Fu K, Weisenburger DD, Greiner TC, ... ... Staudt LM, et al. Genome-wide copy-number analyses reveal genomic abnormalities involved in transformation of follicular lymphoma. Blood. 123: 1681-90. PMID 24037725 DOI: 10.1182/Blood-2013-05-500595  0.301
2014 Younes A, Zinzani PL, Sehn LH, Johnson PWM, Gascoyne RD, Ahmadi T, Bellew KM, Vermeulen J, Zhuang SH, Sun S, Staudt LM, Wilson WH. A randomized, double-blind, placebo-controlled phase 3 study of ibrutinib in combination with rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) in subjects with newly diagnosed nongerminal center B-cell subtype of diffuse large B-cell lymphoma (DLBCL). Journal of Clinical Oncology. 32: TPS8615-TPS8615. DOI: 10.1200/Jco.2014.32.15_Suppl.Tps8615  0.425
2014 Czuczman MS, Davies A, Linton KM, Wagner-Johnston N, Gascoyne RD, Eberhard DA, Salles G, Witzig TE, Zinzani PL, Wright GW, Staudt LM, Repici J, Song D, Manzke O, Lewis ID. A Phase 2/3 Multicenter, Randomized Study Comparing the Efficacy and Safety of Lenalidomide Versus Investigator’s Choice in Relapsed/Refractory DLBCL Blood. 124: 628-628. DOI: 10.1182/Blood.V124.21.628.628  0.302
2014 Dunleavy K, Fanale M, LaCasce A, Noy A, Caimi P, Parekh S, Hayslip JW, Jagadeesh D, Lord RS, Lechowicz MJ, Gaur R, Lucas A, Staudt LM, Steinberg SM, Kahl B, et al. Preliminary Report of a Multicenter Prospective Phase II Study of DA-EPOCH-R in MYC-Rearranged Aggressive B-Cell Lymphoma Blood. 124: 395-395. DOI: 10.1182/Blood.V124.21.395.395  0.348
2014 Shirley CM, Chu SH, Yang Y, Wright GW, Staudt LM, Small D. Genetic and Pharmacologic Notch4 Inhibition Synergizes with FLT3 Tyrosine Kinase Inhibition in Vitro to More Effectively Eliminate FLT3/ITD-Positive Leukemia Cells Blood. 124: 3583-3583. DOI: 10.1182/Blood.V124.21.3583.3583  0.427
2014 Nakagawa M, Schmitz R, Xiao W, Goldman CK, Xu W, Yang Y, Waldmann TA, Staudt LM. A Gain-of-Function CCR4 Mutations in Adult T-Cell Leukemia/Lymphoma (ATLL) Enhance the Chemotactic Abilities and PI3K/AKT Activation Blood. 124: 3566-3566. DOI: 10.1182/Blood.V124.21.3566.3566  0.395
2014 Scott DW, Wright GW, Williams M, Lih J, Jaffe ES, Rosenwald A, Campo E, Chan W(C, Connors JM, Smeland E, Braziel RM, Ott G, Delabie J, Weisenburger DD, Cook JR, ... ... Staudt LM, et al. Accurate Diagnosis of Aggressive B Cell Non-Hodgkin Lymphomas Using Gene Expression Profiling of Formalin-Fixed, Paraffin-Embedded Tissues Blood. 124: 3016-3016. DOI: 10.1182/Blood.V124.21.3016.3016  0.363
2014 Rohr J, Guo S, Hu D, Bouska A, Gascoyne RD, Rosenwald A, Simone P, Zhang W, Xiao W, Wang C, Fu K, Greiner TC, Weisenburger DD, Vose JM, Staudt LM, et al. CD28 Mutations in Peripheral T-Cell Lymphomagenesis and Progression Blood. 124: 1681-1681. DOI: 10.1182/Blood.V124.21.1681.1681  0.327
2014 Kendrick SL, Tus K, Scott DW, Wright G, Jaffe ES, Rosenwald A, Campo E, Chan WC, Connors JM, Braziel RM, Ott G, Delabie J, Cook JR, Weisenburger DD, Greiner TC, ... ... Staudt LM, et al. Cell-of-Origin Subtype Classification of Diffuse Large B-Cell Lymphoma Using the Lymph2Cx Assay Retains Relevance in the Context of BCL2 and MYC Expression Status Blood. 124: 1667-1667. DOI: 10.1182/Blood.V124.21.1667.1667  0.373
2014 Scott DW, Mottok A, Ennishi D, Wright GW, Farinha P, Ben-Neriah S, Kridel R, Barry GS, Hother CE, Savage KJ, Sehn LH, Staudt LM, Connors JM, Rimsza LM, Gascoyne RD. Cell-of-Origin Assignment in Diffuse Large B-Cell Lymphoma Determined By Gene Expression in Formalin-Fixed Paraffin-Embedded Tissue Has Prognostic Significance Independent of IPI and MYC/BCL2 Immunohistochemistry Blood. 124: 1624-1624. DOI: 10.1182/Blood.V124.21.1624.1624  0.406
2014 Roschewski M, Dunleavy K, Pittaluga S, Kong K, Shovlin M, Jaffe ES, Staudt LM, Lai C, Chen CC, Zheng J, Willis TD, Faham M, Wilson WH. Monitoring of Circulating Tumor DNA As Minimal Residual Disease in Diffuse Large B-Cell Lymphoma Blood. 124: 139-139. DOI: 10.1182/Blood.V124.21.139.139  0.317
2014 Kelly PN, Chaudhary D, Young RM, Shaffer A, Robinson S, Romero DL, Kapeller R, Staudt LM. Abstract LB-112: Highly potent and selective interleukin-1 receptor-associated kinase 4 inhibitors for the therapy of lymphoid malignancies Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Lb-112  0.375
2013 Huang X, Meng B, Iqbal J, Ding BB, Perry AM, Cao W, Smith LM, Bi C, Jiang C, Greiner TC, Weisenburger DD, Rimsza L, Rosenwald A, Ott G, Delabie J, ... ... Staudt LM, et al. Activation of the STAT3 signaling pathway is associated with poor survival in diffuse large B-cell lymphoma treated with R-CHOP. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 31: 4520-8. PMID 24220563 DOI: 10.1200/Jco.2012.45.6004  0.418
2013 Sawai CM, Sisirak V, Ghosh HS, Hou EZ, Ceribelli M, Staudt LM, Reizis B. Transcription factor Runx2 controls the development and migration of plasmacytoid dendritic cells. The Journal of Experimental Medicine. 210: 2151-9. PMID 24101375 DOI: 10.1084/Jem.20130443  0.385
2013 Enjuanes A, Albero R, Clot G, Navarro A, Beà S, Pinyol M, Martín-Subero JI, Klapper W, Staudt LM, Jaffe ES, Rimsza L, Braziel RM, Delabie J, Cook JR, Tubbs RR, et al. Genome-wide methylation analyses identify a subset of mantle cell lymphoma with a high number of methylated CpGs and aggressive clinicopathological features International Journal of Cancer. 133: 2852-2863. PMID 23754783 DOI: 10.1002/Ijc.28321  0.37
2013 Dunleavy K, Pittaluga S, Maeda LS, Advani R, Chen CC, Hessler J, Steinberg SM, Grant C, Wright G, Varma G, Staudt LM, Jaffe ES, Wilson WH. Dose-adjusted EPOCH-rituximab therapy in primary mediastinal B-cell lymphoma. The New England Journal of Medicine. 368: 1408-16. PMID 23574119 DOI: 10.1056/Nejmoa1214561  0.408
2013 Lamy L, Ngo VN, Emre NC, Shaffer AL, Yang Y, Tian E, Nair V, Kruhlak MJ, Zingone A, Landgren O, Staudt LM. Control of autophagic cell death by caspase-10 in multiple myeloma. Cancer Cell. 23: 435-49. PMID 23541952 DOI: 10.1016/J.Ccr.2013.02.017  0.768
2013 Sanda T, Tyner JW, Gutierrez A, Ngo VN, Glover J, Chang BH, Yost A, Ma W, Fleischman AG, Zhou W, Yang Y, Kleppe M, Ahn Y, Tatarek J, Kelliher MA, ... ... Staudt LM, et al. TYK2-STAT1-BCL2 pathway dependence in T-cell acute lymphoblastic leukemia. Cancer Discovery. 3: 564-77. PMID 23471820 DOI: 10.1158/2159-8290.Cd-12-0504  0.401
2013 Young RM, Staudt LM. Targeting pathological B cell receptor signalling in lymphoid malignancies. Nature Reviews. Drug Discovery. 12: 229-43. PMID 23449308 DOI: 10.1038/Nrd3937  0.417
2013 Chiorazzi M, Rui L, Yang Y, Ceribelli M, Tishbi N, Maurer CW, Ranuncolo SM, Zhao H, Xu W, Chan WC, Jaffe ES, Gascoyne RD, Campo E, Rosenwald A, Ott G, ... ... Staudt LM, et al. Related F-box proteins control cell death in Caenorhabditis elegans and human lymphoma. Proceedings of the National Academy of Sciences of the United States of America. 110: 3943-8. PMID 23431138 DOI: 10.1073/Pnas.1217271110  0.382
2013 Barlow JH, Faryabi RB, Callén E, Wong N, Malhowski A, Chen HT, Gutierrez-Cruz G, Sun HW, McKinnon P, Wright G, Casellas R, Robbiani DF, Staudt L, Fernandez-Capetillo O, Nussenzweig A. Identification of early replicating fragile sites that contribute to genome instability. Cell. 152: 620-32. PMID 23352430 DOI: 10.1016/J.Cell.2013.01.006  0.349
2013 Yeung CL, Ngo VN, Grohar PJ, Arnaldez FI, Asante A, Wan X, Khan J, Hewitt SM, Khanna C, Staudt LM, Helman LJ. Loss-of-function screen in rhabdomyosarcoma identifies CRKL-YES as a critical signal for tumor growth. Oncogene. 32: 5429-38. PMID 23318429 DOI: 10.1038/Onc.2012.590  0.351
2013 Lim KH, Staudt LM. Toll-like receptor signaling. Cold Spring Harbor Perspectives in Biology. 5: a011247. PMID 23284045 DOI: 10.1101/Cshperspect.A011247  0.309
2013 Kucuk C, Jiang B, Hu X, Gaulard P, Zhang W, Xiao W, Staudt LM, Iqbal J, Zhang W, Cornish A, Kavak P, Alkan C, Gong Q, Yang Q, Sun H, et al. Frequent Activating Mutations Of JAK-STAT Pathway Genes In Natural Killer Cell Lymphomas Blood. 122: 812-812. DOI: 10.1182/Blood.V122.21.812.812  0.423
2013 Scott DW, Wright GW, Williams M, Lih J, Walsh W, Jaffe ES, Rosenwald A, Campo E, Chan WC, Connors JM, Smeland EB, Mottok A, Braziel RM, Ott G, Delabie J, ... ... Staudt LM, et al. Determining Cell-Of-Origin Subtypes In Diffuse Large B-Cell Lymphoma Using Gene Expression Profiling On Formalin-Fixed Paraffin-Embedded Tissue – An L.L.M.P.P. Project Blood. 122: 73-73. DOI: 10.1182/Blood.V122.21.73.73  0.428
2013 Dunleavy K, Pittaluga S, Shovlin M, Pack S, Steinberg SM, Lai CE, Grant C, Hsi ED, Staudt LM, Jaffe ES, Wilson WH. Concurrent Expression Of MYC/BCL2 Protein In Newly Diagnosed DLBCL Is Not Associated With An Inferior Survival Following EPOCH-R Therapy Blood. 122: 3029-3029. DOI: 10.1182/Blood.V122.21.3029.3029  0.393
2013 Roschewski M, Pittaluga S, Dunleavy K, Kong K, Shovlin M, Jaffe ES, Staudt LM, Zheng J, Willis T, Faham M, Wilson WH. DNA Sequencing-Based Monitoring Of Serum Predicts Clinical Relapse Before CT Imaging in Diffuse Large B-Cell Lymphoma Blood. 122: 1767-1767. DOI: 10.1182/Blood.V122.21.1767.1767  0.313
2013 Mathews LA, Guha R, Shinn P, Young RM, Lim K, Keller J, Liu D, Yasgar A, McKnight C, Boxer MB, Duveau DY, Jiang J, Michael S, Mott BT, Patel PR, ... ... Staudt L, et al. Abstract 4543: High-throughput combination screening identifies novel drug-drug pairings for a Bruton's tyrosine kinase inhibitor against the ABC subtype of diffuse large B-cell lymphomas. Cancer Research. 73: 4543-4543. DOI: 10.1158/1538-7445.Am2013-4543  0.382
2013 Kim MKH, Wright G, Staudt L, Annunziata C. Abstract 3144: shRNA library screening by dual shRNA technique identifies CHEK1 as a synthetic lethal gene in the absence of IKKε in ovarian cancer. Cancer Research. 73: 3144-3144. DOI: 10.1158/1538-7445.Am2013-3144  0.374
2013 Lim K, Barton GM, Staudt LM. Abstract 2332: OncogenicMYD88mutants require Toll-like receptors. Cancer Research. 73: 2332-2332. DOI: 10.1158/1538-7445.Am2013-2332  0.377
2012 Young RM, Staudt LM. A new "brew" of MALT1 inhibitors. Cancer Cell. 22: 706-7. PMID 23238011 DOI: 10.1016/J.Ccr.2012.11.011  0.455
2012 Snow AL, Xiao W, Stinson JR, Lu W, Benjamin CD, Zheng L, Pittaluga S, Matthews HF, Schmitz R, Jhavar S, Kuchen S, Kardava L, Wang W, Lamborn IT, Jing H, ... ... Staudt LM, et al. Congenital B cell lymphocytosis explained by novel germline CARD11 mutations Journal of Experimental Medicine. 209: 2247-2261. PMID 23129749 DOI: 10.1084/Jem.20120831  0.46
2012 Shaffer AL, Staudt LM. The case of the missing c-Myc. Nature Immunology. 13: 1029-31. PMID 23080195 DOI: 10.1038/Ni.2455  0.431
2012 Wan X, Yeung C, Kim SY, Dolan JG, Ngo VN, Burkett S, Khan J, Staudt LM, Helman LJ. Identification of FoxM1/Bub1b signaling pathway as a required component for growth and survival of rhabdomyosarcoma. Cancer Research. 72: 5889-99. PMID 23002205 DOI: 10.1158/0008-5472.Can-12-1991  0.35
2012 Sanda T, Lawton LN, Barrasa MI, Fan ZP, Kohlhammer H, Gutierrez A, Ma W, Tatarek J, Ahn Y, Kelliher MA, Jamieson CH, Staudt LM, Young RA, Look AT. Core transcriptional regulatory circuit controlled by the TAL1 complex in human T cell acute lymphoblastic leukemia. Cancer Cell. 22: 209-21. PMID 22897851 DOI: 10.1016/J.Ccr.2012.06.007  0.357
2012 Schmitz R, Young RM, Ceribelli M, Jhavar S, Xiao W, Zhang M, Wright G, Shaffer AL, Hodson DJ, Buras E, Liu X, Powell J, Yang Y, Xu W, Zhao H, ... ... Staudt LM, et al. Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics. Nature. 490: 116-20. PMID 22885699 DOI: 10.1038/Nature11378  0.501
2012 Johnson NA, Slack GW, Savage KJ, Connors JM, Ben-Neriah S, Rogic S, Scott DW, Tan KL, Steidl C, Sehn LH, Chan WC, Iqbal J, Meyer PN, Lenz G, Wright G, ... ... Staudt LM, et al. Concurrent expression of MYC and BCL2 in diffuse large B-cell lymphoma treated with rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 30: 3452-9. PMID 22851565 DOI: 10.1200/Jco.2011.41.0985  0.445
2012 Perry AM, Cardesa-Salzmann TM, Meyer PN, Colomo L, Smith LM, Fu K, Greiner TC, Delabie J, Gascoyne RD, Rimsza L, Jaffe ES, Ott G, Rosenwald A, Braziel RM, Tubbs R, ... ... Staudt LM, et al. A new biologic prognostic model based on immunohistochemistry predicts survival in patients with diffuse large B-cell lymphoma. Blood. 120: 2290-6. PMID 22740447 DOI: 10.1182/Blood-2012-05-430389  0.408
2012 Huang X, Di Liberto M, Jayabalan D, Liang J, Ely S, Bretz J, Shaffer AL, Louie T, Chen I, Randolph S, Hahn WC, Staudt LM, Niesvizky R, Moore MA, Chen-Kiang S. Prolonged early G(1) arrest by selective CDK4/CDK6 inhibition sensitizes myeloma cells to cytotoxic killing through cell cycle-coupled loss of IRF4. Blood. 120: 1095-106. PMID 22718837 DOI: 10.1182/Blood-2012-03-415984  0.381
2012 Yang Y, Shaffer AL, Emre NC, Ceribelli M, Zhang M, Wright G, Xiao W, Powell J, Platig J, Kohlhammer H, Young RM, Zhao H, Yang Y, Xu W, Buggy JJ, ... ... Staudt LM, et al. Exploiting synthetic lethality for the therapy of ABC diffuse large B cell lymphoma. Cancer Cell. 21: 723-37. PMID 22698399 DOI: 10.1016/J.Ccr.2012.05.024  0.811
2012 Kentsis A, Reed C, Rice KL, Sanda T, Rodig SJ, Tholouli E, Christie A, Valk PJ, Delwel R, Ngo V, Kutok JL, Dahlberg SE, Moreau LA, Byers RJ, Christensen JG, ... ... Staudt LM, et al. Autocrine activation of the MET receptor tyrosine kinase in acute myeloid leukemia. Nature Medicine. 18: 1118-22. PMID 22683780 DOI: 10.1038/Nm.2819  0.402
2012 Chen E, Staudt LM, Green AR. Janus kinase deregulation in leukemia and lymphoma. Immunity. 36: 529-41. PMID 22520846 DOI: 10.1016/J.Immuni.2012.03.017  0.329
2012 Lim KH, Yang Y, Staudt LM. Pathogenetic importance and therapeutic implications of NF-κB in lymphoid malignancies. Immunological Reviews. 246: 359-78. PMID 22435566 DOI: 10.1111/J.1600-065X.2012.01105.X  0.366
2012 Deffenbacher KE, Iqbal J, Sanger W, Shen Y, Lachel C, Liu Z, Liu Y, Lim MS, Perkins SL, Fu K, Smith L, Lynch J, Staudt LM, Rimsza LM, Jaffe E, et al. Molecular distinctions between pediatric and adult mature B-cell non-Hodgkin lymphomas identified through genomic profiling. Blood. 119: 3757-66. PMID 22374697 DOI: 10.1182/Blood-2011-05-349662  0.436
2012 Shaffer AL, Young RM, Staudt LM. Pathogenesis of human B cell lymphomas. Annual Review of Immunology. 30: 565-610. PMID 22224767 DOI: 10.1146/Annurev-Immunol-020711-075027  0.504
2012 Rao E, Jiang C, Ji M, Huang X, Iqbal J, Lenz G, Wright G, Staudt LM, Zhao Y, McKeithan TW, Chan WC, Fu K. The miRNA-17 ∼ 92 cluster mediates chemoresistance and enhances tumor growth in mantle cell lymphoma via PI3K/AKT pathway activation Leukemia. 26: 1064-1072. PMID 22116552 DOI: 10.1038/Leu.2011.305  0.319
2012 Staudt LM. Chronic Active B-Cell Receptor Signaling in Lymphoma Blood. 120: SCI-26-SCI-26. DOI: 10.1182/Blood.V120.21.Sci-26.Sci-26  0.454
2012 Wilson WH, Gerecitano JF, Goy A, de Vos S, Kenkre VP, Barr PM, Blum KA, Shustov AR, Advani RH, Lih J, Williams M, Schmitz R, Yang Y, Pittaluga S, Wright G, ... ... Staudt LM, et al. The Bruton's Tyrosine Kinase (BTK) Inhibitor, Ibrutinib (PCI-32765), Has Preferential Activity in the ABC Subtype of Relapsed/Refractory De Novo Diffuse Large B-Cell Lymphoma (DLBCL): Interim Results of a Multicenter, Open-Label, Phase 2 Study Blood. 120: 686-686. DOI: 10.1182/Blood.V120.21.686.686  0.423
2012 Lim K, Romero DL, Chaudhary D, Robinson SD, Staudt LM. IRAK4 Kinase As A Novel Therapeutic Target in the ABC Subtype of Diffuse Large B Cell Lymphoma Blood. 120: 62-62. DOI: 10.1182/Blood.V120.21.62.62  0.439
2012 Böodöor C, Vera G, Kohlmann A, Tan K, Okosun J, Popov N, Araf S, Marzec J, O‘Riain C, Lee A, Clear AJ, Montoto S, Matthews J, Iqbal S, Rajnai H, ... ... Staudt LM, et al. High Incidence of EZH2 Mutations with Variable Mutation Load in Follicular Lymphoma and Its Consequences for EZH2 Targeted Therapy Blood. 120: 545-545. DOI: 10.1182/Blood.V120.21.545.545  0.304
2012 Bouska A, McKeithan T, Deffenbacher KE, Lachel C, Wright GW, Iqbal J, Smith LM, Liu Z, Kucuk C, Bertoni F, Rinaldi A, Fitzgibbon J, Fu K, Weisenburger DD, Greiner TC, ... ... Staudt LM, et al. Genetic Abnormalities in Follicular Lymphoma and Transformed Follicular Lymphoma. Blood. 120: 2648-2648. DOI: 10.1182/Blood.V120.21.2648.2648  0.359
2012 Sanda T, Tyner JW, Gutierrez A, Ngo VN, Glover JM, Chang BH, Yost AJ, Weng AP, Ma W, Tatarek J, Fleischman AG, Ahn Y, Yang Y, Zhou W, Neuberg DS, ... ... Staudt LM, et al. TYK2-STAT1 Pathway Positively Regulates BCL2 Gene Expression in T-Cell Acute Lymphoblastic Leukemia Blood. 120: 1470-1470. DOI: 10.1182/Blood.V120.21.1470.1470  0.426
2012 Staudt LM. Abstract IA19: New therapeutic strategies for lymphomas inspired by functional and structural genomics Cancer Research. 72: IA19-IA19. DOI: 10.1158/1538-7445.Nonrna12-Ia19  0.347
2011 Leich E, Zamo A, Horn H, Haralambieva E, Puppe B, Gascoyne RD, Chan WC, Braziel RM, Rimsza LM, Weisenburger DD, Delabie J, Jaffe ES, Fitzgibbon J, Staudt LM, Mueller-Hermelink HK, et al. MicroRNA profiles of t(14;18)-negative follicular lymphoma support a late germinal center B-cell phenotype. Blood. 118: 5550-8. PMID 21960592 DOI: 10.1182/Blood-2011-06-361972  0.348
2011 Iqbal J, Meyer PN, Smith LM, Johnson NA, Vose JM, Greiner TC, Connors JM, Staudt LM, Rimsza L, Jaffe E, Rosenwald A, Ott G, Delabie J, Campo E, Braziel RM, et al. BCL2 predicts survival in germinal center B-cell-like diffuse large B-cell lymphoma treated with CHOP-like therapy and rituximab. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 7785-95. PMID 21933893 DOI: 10.1158/1078-0432.Ccr-11-0267  0.458
2011 Morton LM, Cerhan JR, Hartge P, Vasef MA, Neppalli VT, Natkunam Y, Dogan A, Dave BJ, Jain S, Levy R, Lossos IS, Cozen W, Davis S, Schenk MJ, Maurer MJ, ... ... Staudt LM, et al. Immunostaining to identify molecular subtypes of diffuse large B-cell lymphoma in a population-based epidemiologic study in the pre-rituximab era. International Journal of Molecular Epidemiology and Genetics. 2: 245-52. PMID 21915363  0.33
2011 Cardesa-Salzmann TM, Colomo L, Gutierrez G, Chan WC, Weisenburger D, Climent F, González-Barca E, Mercadal S, Arenillas L, Serrano S, Tubbs R, Delabie J, Gascoyne RD, Connors JM, Mate JL, ... ... Staudt L, et al. High microvessel density determines a poor outcome in patients with diffuse large B-cell lymphoma treated with rituximab plus chemotherapy. Haematologica. 96: 996-1001. PMID 21546504 DOI: 10.3324/Haematol.2010.037408  0.44
2011 Eberle FC, Rodriguez-Canales J, Wei L, Hanson JC, Killian JK, Sun HW, Adams LG, Hewitt SM, Wilson WH, Pittaluga S, Meltzer PS, Staudt LM, Emmert-Buck MR, Jaffe ES. Methylation profiling of mediastinal gray zone lymphoma reveals a distinctive signature with elements shared by classical Hodgkin's lymphoma and primary mediastinal large B-cell lymphoma. Haematologica. 96: 558-66. PMID 21454882 DOI: 10.1182/Blood.V116.21.747.747  0.417
2011 Steidl C, Shah SP, Woolcock BW, Rui L, Kawahara M, Farinha P, Johnson NA, Zhao Y, Telenius A, Neriah SB, McPherson A, Meissner B, Okoye UC, Diepstra A, van den Berg A, ... ... Staudt LM, et al. MHC class II transactivator CIITA is a recurrent gene fusion partner in lymphoid cancers. Nature. 471: 377-81. PMID 21368758 DOI: 10.1038/Nature09754  0.488
2011 Rimsza LM, Wright G, Schwartz M, Chan WC, Jaffe ES, Gascoyne RD, Campo E, Rosenwald A, Ott G, Cook JR, Tubbs RR, Braziel RM, Delabie J, Miller TP, Staudt LM. Accurate classification of diffuse large B-cell lymphoma into germinal center and activated B-cell subtypes using a nuclease protection assay on formalin-fixed, paraffin-embedded tissues Clinical Cancer Research. 17: 3727-3732. PMID 21364035 DOI: 10.1158/1078-0432.Ccr-10-2573  0.448
2011 Ngo VN, Young RM, Schmitz R, Jhavar S, Xiao W, Lim KH, Kohlhammer H, Xu W, Yang Y, Zhao H, Shaffer AL, Romesser P, Wright G, Powell J, Rosenwald A, ... ... Staudt LM, et al. Oncogenically active MYD88 mutations in human lymphoma. Nature. 470: 115-9. PMID 21179087 DOI: 10.1038/Nature09671  0.415
2011 Meyer PN, Fu K, Greiner T, Smith L, Delabie J, Gascoyne R, Ott G, Rosenwald A, Braziel R, Campo E, Vose J, Lenz G, Staudt L, Chan W, Weisenburger DD. The stromal cell marker SPARC predicts for survival in patients with diffuse large B-cell lymphoma treated with rituximab. American Journal of Clinical Pathology. 135: 54-61. PMID 21173124 DOI: 10.1309/Ajcpjx4Bjv9Nlqhy  0.44
2011 Annunziata CM, Hernandez L, Davis RE, Zingone A, Lamy L, Lam LT, Hurt EM, Shaffer AL, Kuehl WM, Staudt LM. A mechanistic rationale for MEK inhibitor therapy in myeloma based on blockade of MAF oncogene expression. Blood. 117: 2396-404. PMID 21163924 DOI: 10.1182/Blood-2010-04-278788  0.401
2011 Meyer PN, Fu K, Greiner TC, Smith LM, Delabie J, Gascoyne RD, Ott G, Rosenwald A, Braziel RM, Campo E, Vose JM, Lenz G, Staudt LM, Chan WC, Weisenburger DD. Immunohistochemical methods for predicting cell of origin and survival in patients with diffuse large B-cell lymphoma treated with rituximab. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 200-7. PMID 21135273 DOI: 10.1200/Jco.2010.30.0368  0.413
2011 Martinez-Garcia E, Popovic R, Min DJ, Sweet SM, Thomas PM, Zamdborg L, Heffner A, Will C, Lamy L, Staudt LM, Levens DL, Kelleher NL, Licht JD. The MMSET histone methyl transferase switches global histone methylation and alters gene expression in t(4;14) multiple myeloma cells. Blood. 117: 211-20. PMID 20974671 DOI: 10.1182/Blood-2010-07-298349  0.355
2011 Pérez-Galán P, Mora-Jensen H, Weniger MA, Shaffer AL, Rizzatti EG, Chapman CM, Mo CC, Stennett LS, Rader C, Liu P, Raghavachari N, Stetler-Stevenson M, Yuan C, Pittaluga S, Maric I, ... ... Staudt LM, et al. Bortezomib resistance in mantle cell lymphoma is associated with plasmacytic differentiation. Blood. 117: 542-52. PMID 20956803 DOI: 10.1182/Blood-2010-02-269514  0.396
2011 Schmitz R, Jhavar S, Xiao W, Liu X, Powell J, Wright GW, Chan WC, Jaffe ES, Gascoyne RD, Campo E, Rosenwald A, Ott G, Delabie J, Rimsza LM, Staudt LM. Recurrent Oncogenic Mutations in CCND3 in Aggressive Lymphomas Blood. 118: 435-435. DOI: 10.1182/Blood.V118.21.435.435  0.468
2011 Staudt LM, Dunleavy K, Buggy JJ, Hedrick E, Lucas N, Pittaluga S, Jhavar S, Schmitz R, Williams M, Lih J, Jaffe ES, Wilson WH. The Bruton's Tyrosine Kinase (Btk) Inhibitor PCI-32765 Modulates Chronic Active BCR Signaling and Induces Tumor Regression in Relapsed/Refractory ABC DLBCL Blood. 118: 2716-2716. DOI: 10.1182/Blood.V118.21.2716.2716  0.402
2011 Kentsis A, Sanda T, Reed C, Rodig SJ, Tholouli E, Ngo V, Kutok JL, Dahlberg SE, Moreau LA, Vande Woude G, Christensen J, Byers R, Kung AL, Staudt LM, Look T. Combined Targeting of the MET and FGF Receptor Tyrosine Kinases Induces Sustained AML Cell Death by Preventing Compensatory Upregulation of HGF in Response to MET Kinase Inhibition Blood. 118: 1405-1405. DOI: 10.1182/Blood.V118.21.1405.1405  0.379
2011 Emre NCT, Shaffer AL, Wright GW, Kohlhammer H, Staudt LM. Abstract LB-248: IRF4 as a critical regulator and potential therapeutic target in ABC type diffuse large B-cell lymphoma Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Lb-248  0.515
2011 Sanda T, Tyner JW, Gutierrez A, Ngo VN, Moriggl R, Ahn Y, Glover J, Chang BH, Willis SG, Zhou W, Gray NS, Staudt LM, Druker BJ, Look AT. Abstract 2809: Pathway dependence on the tyrosine kinase TYK2 in T-cell acute lymphoblastic leukemia Cancer Research. 71: 2809-2809. DOI: 10.1158/1538-7445.Am2011-2809  0.403
2010 Rui L, Emre NC, Kruhlak MJ, Chung HJ, Steidl C, Slack G, Wright GW, Lenz G, Ngo VN, Shaffer AL, Xu W, Zhao H, Yang Y, Lamy L, Davis RE, ... ... Staudt LM, et al. Cooperative epigenetic modulation by cancer amplicon genes. Cancer Cell. 18: 590-605. PMID 21156283 DOI: 10.1016/J.Ccr.2010.11.013  0.786
2010 Wang Y, Ngo VN, Marani M, Yang Y, Wright G, Staudt LM, Downward J. Critical role for transcriptional repressor Snail2 in transformation by oncogenic RAS in colorectal carcinoma cells. Oncogene. 29: 4658-70. PMID 20562906 DOI: 10.1038/Onc.2010.218  0.358
2010 Milhollen MA, Traore T, Adams-Duffy J, Thomas MP, Berger AJ, Dang L, Dick LR, Garnsey JJ, Koenig E, Langston SP, Manfredi M, Narayanan U, Rolfe M, Staudt LM, Soucy TA, et al. MLN4924, a NEDD8-activating enzyme inhibitor, is active in diffuse large B-cell lymphoma models: rationale for treatment of NF-{kappa}B-dependent lymphoma. Blood. 116: 1515-23. PMID 20525923 DOI: 10.1182/Blood-2010-03-272567  0.449
2010 Staudt LM. Oncogenic activation of NF-kappaB. Cold Spring Harbor Perspectives in Biology. 2: a000109. PMID 20516126 DOI: 10.1101/Cshperspect.A000109  0.404
2010 Hartmann EM, Campo E, Wright G, Lenz G, Salaverria I, Jares P, Xiao W, Braziel RM, Rimsza LM, Chan WC, Weisenburger DD, Delabie J, Jaffe ES, Gascoyne RD, Dave SS, ... ... Staudt LM, et al. Pathway discovery in mantle cell lymphoma by integrated analysis of high-resolution gene expression and copy number profiling. Blood. 116: 953-61. PMID 20421449 DOI: 10.1182/Blood-2010-01-263806  0.424
2010 Steidl C, Lee T, Shah SP, Farinha P, Han G, Nayar T, Delaney A, Jones SJ, Iqbal J, Weisenburger DD, Bast MA, Rosenwald A, Muller-Hermelink HK, Rimsza LM, Campo E, ... ... Staudt LM, et al. Tumor-associated macrophages and survival in classic Hodgkin's lymphoma New England Journal of Medicine. 362: 875-885. PMID 20220182 DOI: 10.1056/Nejmoa0905680  0.355
2010 Davis RE, Ngo VN, Lenz G, Tolar P, Young RM, Romesser PB, Kohlhammer H, Lamy L, Zhao H, Yang Y, Xu W, Shaffer AL, Wright G, Xiao W, Powell J, ... ... Staudt LM, et al. Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma. Nature. 463: 88-92. PMID 20054396 DOI: 10.1038/Nature08638  0.47
2010 Sanda T, Tyner JW, Gutierrez A, Ngo VN, Moriggl R, Ahn Y, Glover JM, Chang BH, Willis SG, Staudt LM, Druker BJ, Look AT. Pathway Dependence on the Tyrosine Kinase TYK2 and Its Mediator STAT1 In T-Cell Acute Lymphoblastic Leukemia Blood. 116: 3155-3155. DOI: 10.1182/Blood.V116.21.3155.3155  0.402
2010 Johnson NA, Connors JM, Ben-Neriah S, Rogic S, Savage KJ, Steidl C, Horsman DE, Slack GW, Sehn L, Chan W, Iqbal J, Meyer PN, Lenz G, Wright GW, Rimsza LM, ... ... Staudt LM, et al. Concurrent BCL2 and MYC Protein Expression by Immunohistochemistry Determines Clinical Outcome In DLBCL Patients Treated with R-CHOP Blood. 116: 2005-2005. DOI: 10.1182/Blood.V116.21.2005.2005  0.412
2010 Kentsis A, Sanda T, Ngo V, Rodig SJ, Kutok J, Tholouli E, Byers R, Woude GV, Kung AL, Staudt LM, Look AT. Aberrant Expression of Hepatocyte Growth Factor Induces Autocrine MET Activation Providing a Novel Therapeutic Target In Acute Myeloid Leukemia. Blood. 116: 1042-1042. DOI: 10.1182/Blood.V116.21.1042.1042  0.429
2010 Ranuncolo SM, Ngo V, Xiao W, Wright G, Staudt LM. Abstract 3898: Octamer Binding Protein-2 (Oct-2): A non-oncogene addiction in germinal center derived lymphomas and a promising therapeutic target Cancer Research. 70: 3898-3898. DOI: 10.1158/1538-7445.Am10-3898  0.508
2009 Hailfinger S, Lenz G, Ngo V, Posvitz-Fejfar A, Rebeaud F, Guzzardi M, Penas EM, Dierlamm J, Chan WC, Staudt LM, Thome M. Essential role of MALT1 protease activity in activated B cell-like diffuse large B-cell lymphoma. Proceedings of the National Academy of Sciences of the United States of America. 106: 19946-51. PMID 19897720 DOI: 10.1073/Pnas.0907511106  0.446
2009 Mozos A, Royo C, Hartmann E, De Jong D, Baró C, Valera A, Fu K, Weisenburger DD, Delabie J, Chuang SS, Jaffe ES, Ruiz-Marcellan C, Dave S, Rimsza L, Braziel R, ... ... Staudt LM, et al. SOX11 expression is highly specific for mantle cell lymphoma and identifies the cyclin D1-negative subtype. Haematologica. 94: 1555-62. PMID 19880778 DOI: 10.3324/Haematol.2009.010264  0.466
2009 Wilkinson ST, Fernandez DR, Murphy SP, Braziel RM, Campo E, Chan WC, Delabie J, Gascoyne RD, Staudt LM, Jaffe ES, Rosenwald A, Rimsza LM. Decreased major histocompatibility complex class II expression in diffuse large B-cell lymphoma does not correlate with CpG methylation of class II transactivator promoters III and IV. Leukemia & Lymphoma. 50: 1875-8. PMID 19814686 DOI: 10.3109/10428190903297531  0.399
2009 Taylor JG, Cheuk AT, Tsang PS, Chung JY, Song YK, Desai K, Yu Y, Chen QR, Shah K, Youngblood V, Fang J, Kim SY, Yeung C, Helman LJ, Mendoza A, ... ... Staudt LM, et al. Identification of FGFR4-activating mutations in human rhabdomyosarcomas that promote metastasis in xenotransplanted models. The Journal of Clinical Investigation. 119: 3395-407. PMID 19809159 DOI: 10.1172/Jci39703  0.393
2009 Choi WW, Weisenburger DD, Greiner TC, Piris MA, Banham AH, Delabie J, Braziel RM, Geng H, Iqbal J, Lenz G, Vose JM, Hans CP, Fu K, Smith LM, Li M, ... ... Staudt LM, et al. A new immunostain algorithm classifies diffuse large B-cell lymphoma into molecular subtypes with high accuracy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 5494-502. PMID 19706817 DOI: 10.1158/1078-0432.Ccr-09-0113  0.441
2009 O'Riain C, O'Shea DM, Yang Y, Le Dieu R, Gribben JG, Summers K, Yeboah-Afari J, Bhaw-Rosun L, Fleischmann C, Mein CA, Crook T, Smith P, Kelly G, Rosenwald A, Ott G, ... ... Staudt LM, et al. Array-based DNA methylation profiling in follicular lymphoma. Leukemia. 23: 1858-66. PMID 19587707 DOI: 10.1038/Leu.2009.114  0.347
2009 Leich E, Salaverria I, Bea S, Zettl A, Wright G, Moreno V, Gascoyne RD, Chan WC, Braziel RM, Rimsza LM, Weisenburger DD, Delabie J, Jaffe ES, Lister A, Fitzgibbon J, ... Staudt LM, et al. Follicular lymphomas with and without translocation t(14;18) differ in gene expression profiles and genetic alterations. Blood. 114: 826-34. PMID 19471018 DOI: 10.1182/Blood-2009-01-198580  0.372
2009 Shaffer AL, Emre NC, Romesser PB, Staudt LM. IRF4: Immunity. Malignancy! Therapy? Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 2954-61. PMID 19383829 DOI: 10.1158/1078-0432.Ccr-08-1845  0.806
2009 Dunleavy K, Pittaluga S, Czuczman MS, Dave SS, Wright G, Grant N, Shovlin M, Jaffe ES, Janik JE, Staudt LM, Wilson WH. Differential efficacy of bortezomib plus chemotherapy within molecular subtypes of diffuse large B-cell lymphoma. Blood. 113: 6069-76. PMID 19380866 DOI: 10.1182/Blood-2009-01-199679  0.466
2009 Faumont N, Durand-Panteix S, Schlee M, Grömminger S, Schuhmacher M, Hölzel M, Laux G, Mailhammer R, Rosenwald A, Staudt LM, Bornkamm GW, Feuillard J. c-Myc and Rel/NF-κB are the two master transcriptional systems activated in the latency III program of Epstein-Barr virus-immortalized B cells Journal of Virology. 83: 5014-5027. PMID 19264782 DOI: 10.1128/Jvi.02264-08  0.446
2009 Rimsza LM, Chan WC, Gascoyne RD, Campo E, Jaffe ES, Staudt LM, Delabie J, Rosenwald A, Murphy SP. CIITA or RFX coding region loss of function mutations occur rarely in diffuse large B-cell lymphoma cases and cell lines with low levels of major histocompatibility complex class II expression. Haematologica. 94: 596-8. PMID 19229048 DOI: 10.3324/Haematol.2008.000752  0.456
2009 Bidère N, Ngo VN, Lee J, Collins C, Zheng L, Wan F, Davis RE, Lenz G, Anderson DE, Arnoult D, Vazquez A, Sakai K, Zhang J, Meng Z, Veenstra TD, ... Staudt LM, et al. Casein kinase 1alpha governs antigen-receptor-induced NF-kappaB activation and human lymphoma cell survival. Nature. 458: 92-6. PMID 19118383 DOI: 10.1038/Nature07613  0.424
2009 Meragelman TL, Scudiero DA, Davis RE, Staudt LM, McCloud TG, Cardellina JH, Shoemaker RH. Inhibitors of the NF-κB activation pathway from cryptocarya rugulosa Journal of Natural Products. 72: 336-339. PMID 19093800 DOI: 10.1021/Np800350X  0.357
2009 Martinez-Garcia E, Popovic R, Min D, Will C, Meyer J, Staudt LM, Lamy L, Lauring J, Cheng Z, Patel D, Licht JD. The MMSET Histone Methyl Transferase Alters Chromatin Structure and Gene Expression in t(4;14) Multiple Myeloma Cells. Blood. 114: 675-675. DOI: 10.1182/Blood.V114.22.675.675  0.423
2009 Rimsza LM, Wright G, Schwartz M, Chan WC, Jaffe ES, Gascoyne RD, Campo E, Rosenwald A, Ott G, Cook JR, Tubbs RR, Braziel RM, Delabie J, Miller TP, Fisher RI, ... Staudt LM, et al. Accurate Classification of Diffuse Large B Cell Lymphoma Into Germinal Center and Activated B Cell Subtypes Using a Nuclease Protection Assay On Formalin Fixed Paraffin Embedded Tissue: A Study From the Lymphoma and Leukemia Molecular Profiling Project. Blood. 114: 620-620. DOI: 10.1182/Blood.V114.22.620.620  0.417
2009 Ranuncolo SM, Ngo V, Lenz G, Xiao W, Wright G, Staudt LM. OCT2 (Octamer Binding Protein 2): An Essential Role in Germinal Center B Cell Differentiation and the “Achilles Heel” of Derived Lymphomas. Blood. 114: 362-362. DOI: 10.1182/Blood.V114.22.362.362  0.511
2009 Deffenbacher KE, Iqbal J, Liu Z, Perkins SL, Lim MS, Fu K, Shen Y, Staudt LM, Rimsza LM, Jaffe ES, Rosenwald A, Ott G, Delabie J, Campo E, Gascoyne RD, et al. Chromosomal Alterations in Gene Expression-Defined Pediatric Aggressive B-Cell Non-Hodgkin Lymphoma (B-NHL). Blood. 114: 2922-2922. DOI: 10.1182/Blood.V114.22.2922.2922  0.45
2009 Perez Galan P, Jensen HM, Weniger MA, Chapman CM, Liu P, Raghavachari N, Shaffer AL, Staudt LM, Wiestner A. Bortezomib Resistance in Mantle Cell Lymphoma Is Associated with Expression of a Plasmacytoid Differentiation Program. Blood. 114: 287-287. DOI: 10.1182/Blood.V114.22.287.287  0.425
2009 Cardesa-Salzmann TM, Colomo L, Climent F, Gonzalez-Barca E, López-Guillermo A, Gutierrez G, Mercadal S, Gascoyne RD, Connors JM, Rimsza LM, Braziel RM, Cook JR, Tubbs RR, Rosenwald A, Ott G, ... ... Staudt LM, et al. High Microvascular Density Correlates with Poor Outcome in Patients with Diffuse Large B-Cell Lymphoma (DLBCL) Treated with Rituximab Plus Chemotherapy (R-CT). Blood. 114: 1948-1948. DOI: 10.1182/Blood.V114.22.1948.1948  0.407
2009 Johnson NA, Ben-Neriah S, Savage KJ, Lee T, Horsman DE, Connors JM, Chan WC, Lenz G, Wright G, Rimsza LM, Braziel RM, Cook JR, Tubbs RR, Weisenburger DD, Campo E, ... ... Staudt LM, et al. MYC Translocations and Expression Are Clinically Important in R-CHOP Treated Patients with De Novo DLBCL. Blood. 114: 1100-1100. DOI: 10.1182/Blood.V114.22.1100.1100  0.444
2009 Dunleavy K, Pittaluga S, Tay K, Grant N, Chen CC, Shovlin M, Steinberg S, Staudt LM, Jaffe ES, Janik JE, Wilson WH. Comparative Clinical and Biological Features of Primary Mediastinal B-Cell Lymphoma (PMBL) and Mediastinal Grey Zone Lymphoma (MGZL). Blood. 114: 106-106. DOI: 10.1182/Blood.V114.22.106.106  0.359
2009 Kuehl W, Demchenko Y, Glebov O, Zingone A, Staudt L, Brents L, Weiss B, Barlogie B, Shaughnessy J, Bergsagel P. B557 Molecular Pathogenesis of MGUS and Multiple Myeloma Clinical Lymphoma and Myeloma. 9: S149. DOI: 10.1016/S1557-9190(11)70771-5  0.343
2008 Lam LT, Davis RE, Ngo VN, Lenz G, Wright G, Xu W, Zhao H, Yu X, Dang L, Staudt LM. Compensatory IKKalpha activation of classical NF-kappaB signaling during IKKbeta inhibition identified by an RNA interference sensitization screen. Proceedings of the National Academy of Sciences of the United States of America. 105: 20798-803. PMID 19104039 DOI: 10.1073/Pnas.0806491106  0.419
2008 Lenz G, Wright G, Dave SS, Xiao W, Powell J, Zhao H, Xu W, Tan B, Goldschmidt N, Iqbal J, Vose J, Bast M, Fu K, Weisenburger DD, Greiner TC, ... ... Staudt LM, et al. Stromal gene signatures in large-B-cell lymphomas. The New England Journal of Medicine. 359: 2313-23. PMID 19038878 DOI: 10.1056/Nejmoa0802885  0.472
2008 Lenz G, Wright GW, Emre NC, Kohlhammer H, Dave SS, Davis RE, Carty S, Lam LT, Shaffer AL, Xiao W, Powell J, Rosenwald A, Ott G, Muller-Hermelink HK, Gascoyne RD, ... ... Staudt LM, et al. Molecular subtypes of diffuse large B-cell lymphoma arise by distinct genetic pathways. Proceedings of the National Academy of Sciences of the United States of America. 105: 13520-5. PMID 18765795 DOI: 10.1073/Pnas.0804295105  0.823
2008 Salaverria I, Zettl A, Beà S, Hartmann EM, Dave SS, Wright GW, Boerma EJ, Kluin PM, Ott G, Chan WC, Weisenburger DD, Lopez-Guillermo A, Gascoyne RD, Delabie J, Rimsza LM, ... ... Staudt LM, et al. Chromosomal alterations detected by comparative genomic hybridization in subgroups of gene expression-defined Burkitt's lymphoma. Haematologica. 93: 1327-34. PMID 18698080 DOI: 10.3324/Haematol.13071  0.439
2008 O'Shea D, O'Riain C, Taylor C, Waters R, Carlotti E, Macdougall F, Gribben J, Rosenwald A, Ott G, Rimsza LM, Smeland EB, Johnson N, Campo E, Greiner TC, Chan WC, ... ... Staudt LM, et al. The presence of TP53 mutation at diagnosis of follicular lymphoma identifies a high-risk group of patients with shortened time to disease progression and poorer overall survival. Blood. 112: 3126-9. PMID 18628487 DOI: 10.1182/Blood-2008-05-154013  0.358
2008 Shaffer AL, Emre NC, Lamy L, Ngo VN, Wright G, Xiao W, Powell J, Dave S, Yu X, Zhao H, Zeng Y, Chen B, Epstein J, Staudt LM. IRF4 addiction in multiple myeloma. Nature. 454: 226-31. PMID 18568025 DOI: 10.1038/Nature07064  0.813
2008 Young KH, Leroy K, Møller MB, Colleoni GW, Sánchez-Beato M, Kerbauy FR, Haioun C, Eickhoff JC, Young AH, Gaulard P, Piris MA, Oberley TD, Rehrauer WM, Kahl BS, Malter JS, ... ... Staudt LM, et al. Structural profiles of TP53 gene mutations predict clinical outcome in diffuse large B-cell lymphoma: an international collaborative study. Blood. 112: 3088-98. PMID 18559976 DOI: 10.1182/Blood-2008-01-129783  0.368
2008 McKean D, Huppi K, Bell M, Staudt L, Gerhard W, Weigert M. Pillars article: Generation of antibody diversity in the immune response of BALB/c mice to influenza virus hemagglutinin. Proc. Natl. Acad. Sci. USA, 81: 3180-3184, May 1984 Journal of Immunology (Baltimore, Md. : 1950). 180: 5765-5769. PMID 18424692  0.525
2008 Wilson WH, Dunleavy K, Pittaluga S, Hegde U, Grant N, Steinberg SM, Raffeld M, Gutierrez M, Chabner BA, Staudt L, Jaffe ES, Janik JE. Phase II study of dose-adjusted EPOCH and rituximab in untreated diffuse large B-cell lymphoma with analysis of germinal center and post-germinal center biomarkers. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 26: 2717-24. PMID 18378569 DOI: 10.1200/Jco.2007.13.1391  0.419
2008 Lenz G, Davis RE, Ngo VN, Lam L, George TC, Wright GW, Dave SS, Zhao H, Xu W, Rosenwald A, Ott G, Muller-Hermelink HK, Gascoyne RD, Connors JM, Rimsza LM, ... ... Staudt LM, et al. Oncogenic CARD11 mutations in human diffuse large B cell lymphoma. Science (New York, N.Y.). 319: 1676-9. PMID 18323416 DOI: 10.1126/Science.1153629  0.478
2008 Baskar S, Kwong KY, Hofer T, Levy JM, Kennedy MG, Lee E, Staudt LM, Wilson WH, Wiestner A, Rader C. Unique cell surface expression of receptor tyrosine kinase ROR1 in human B-cell chronic lymphocytic leukemia. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 396-404. PMID 18223214 DOI: 10.1158/1078-0432.Ccr-07-1823  0.457
2008 Lam LT, Wright G, Davis RE, Lenz G, Farinha P, Dang L, Chan JW, Rosenwald A, Gascoyne RD, Staudt LM. Cooperative signaling through the signal transducer and activator of transcription 3 and nuclear factor-{kappa}B pathways in subtypes of diffuse large B-cell lymphoma. Blood. 111: 3701-13. PMID 18160665 DOI: 10.1182/Blood-2007-09-111948  0.401
2008 Xie Y, Deng S, Thomas CJ, Liu Y, Zhang YQ, Rinderspacher A, Huang W, Gong G, Wyler M, Cayanis E, Aulner N, Többen U, Chung C, Pampou S, Southall N, ... ... Staudt LM, et al. Identification of N-(quinolin-8-yl)benzenesulfonamides as agents capable of down-regulating NFkappaB activity within two separate high-throughput screens of NFkappaB activation. Bioorganic & Medicinal Chemistry Letters. 18: 329-35. PMID 18024113 DOI: 10.1016/J.Bmcl.2007.10.100  0.308
2008 Steidl C, Lee T, Shah SP, Han G, Nayar T, Delaney A, Jones S, Chan WC, Rosenwald A, Rimsza LM, Campo E, Jaffe ES, Staudt LM, Lenz G, Connors JM, et al. Genome-Wide Expression Profiling Predicts Treatment Outcome in Classical Hodgkin Lymphoma Blood. 112: 520-520. DOI: 10.1182/Blood.V112.11.520.520  0.43
2008 Lenz G, Wright G, Dave S, Xiao W, Powell J, Zhao H, Xu W, Tan B, Goldschmidt N, Iqbal J, Vose J, Bast MA, Fu K, Weisenburger DD, Greiner TC, ... ... Staudt LM, et al. Molecular Signatures Implicate Innate Immune Cells, Fibrosis, and Angiogenesis in Survival Following R-CHOP Treatment of Diffuse Large B Cell Lymphoma Blood. 112: 475-475. DOI: 10.1182/BLOOD.V112.11.475.475  0.343
2008 Rao E, McKeithan T, Jiang C, Ji M, Iqbal J, Wright G, Staudt LM, Zhao Y, Chan WC, Fu K. The Mir-17~92 Cluster Enhances Cell Growth and Resistance to Chemotherapy in Mantle Cell Lymphoma by Down-Regulating PTEN, PHLPP2 and BIM Blood. 112: 373-373. DOI: 10.1182/Blood.V112.11.373.373  0.313
2008 Deffenbacher KE, Wright G, Iqbal J, Geng H, O’Shea D, Lister TA, Fitzgibbon J, Fu K, Liu Z, Weisenburger D, Greiner TC, Gascoyne RD, Rosenwald A, Campo E, Rimsza LM, ... ... Staudt LM, et al. Genetic Abnormalities Involved in the Development and Progression of Follicular Lymphoma. Blood. 112: 2049-2049. DOI: 10.1182/Blood.V112.11.2049.2049  0.341
2008 Wilkinson ST, Fernandez DR, Murphy SP, Chan WC, Gascoyne RD, Campo E, Jaffe ES, Staudt LM, Delabie J, Rosenwald A, Rimsza LM. Loss of CIITA and MHC Class II Expression in Diffuse Large B-Cell Lymphoma Is Not Explained by Methylation of CIITA Promoters III and IV. Blood. 112: 1786-1786. DOI: 10.1182/Blood.V112.11.1786.1786  0.368
2008 Lam LT, Davis RE, Ngo V, Wright G, Lenz G, Zhao H, Yu X, Dang L, Staudt LM. Abstract LB-239: An rnai sensitization screen identifies compensatory IKKα activation during IKKβ inhibition Cancer Research. 68. DOI: 10.1158/1538-7445.Am2008-Lb-239  0.444
2007 Wan F, Anderson DE, Barnitz RA, Snow A, Bidere N, Zheng L, Hegde V, Lam LT, Staudt LM, Levens D, Deutsch WA, Lenardo MJ. Ribosomal protein S3: a KH domain subunit in NF-kappaB complexes that mediates selective gene regulation. Cell. 131: 927-39. PMID 18045535 DOI: 10.1016/J.Cell.2007.10.009  0.356
2007 Young KH, Weisenburger DD, Dave BJ, Smith L, Sanger W, Iqbal J, Campo E, Delabie J, Gascoyne RD, Ott G, Rimsza L, Müller-Hermelink HK, Jaffe ES, Rosenwald A, Staudt LM, et al. Mutations in the DNA-binding codons of TP53, which are associated with decreased expression of TRAILreceptor-2, predict for poor survival in diffuse large B-cell lymphoma. Blood. 110: 4396-405. PMID 17881637 DOI: 10.1182/Blood-2007-02-072082  0.386
2007 Kimm LR, deLeeuw RJ, Savage KJ, Rosenwald A, Campo E, Delabie J, Ott G, Muller-Hermelink HK, Jaffe ES, Rimsza LM, Weisenburger DD, Chan WC, Staudt LM, Connors JM, Gascoyne RD, et al. Frequent occurrence of deletions in primary mediastinal B-cell lymphoma. Genes, Chromosomes & Cancer. 46: 1090-7. PMID 17823928 DOI: 10.1002/Gcc.20495  0.34
2007 Hystad ME, Myklebust JH, Bø TH, Sivertsen EA, Rian E, Forfang L, Munthe E, Rosenwald A, Chiorazzi M, Jonassen I, Staudt LM, Smeland EB. Characterization of early stages of human B cell development by gene expression profiling. Journal of Immunology (Baltimore, Md. : 1950). 179: 3662-71. PMID 17785802 DOI: 10.4049/Jimmunol.179.6.3662  0.475
2007 Annunziata CM, Davis RE, Demchenko Y, Bellamy W, Gabrea A, Zhan F, Lenz G, Hanamura I, Wright G, Xiao W, Dave S, Hurt EM, Tan B, Zhao H, Stephens O, ... ... Staudt LM, et al. Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma. Cancer Cell. 12: 115-30. PMID 17692804 DOI: 10.1016/J.Ccr.2007.07.004  0.391
2007 Iqbal J, Greiner TC, Patel K, Dave BJ, Smith L, Ji J, Wright G, Sanger WG, Pickering DL, Jain S, Horsman DE, Shen Y, Fu K, Weisenburger DD, Hans CP, ... ... Staudt LM, et al. Distinctive patterns of BCL6 molecular alterations and their functional consequences in different subgroups of diffuse large B-cell lymphoma. Leukemia. 21: 2332-43. PMID 17625604 DOI: 10.1038/Sj.Leu.2404856  0.478
2007 Dunleavy K, Staudt LM, Wilson WH. The BCL-2 biomarker in the era of molecular diagnosis of diffuse large B-cell lymphoma. Leukemia & Lymphoma. 48: 1061-3. PMID 17577765 DOI: 10.1080/10428190701420467  0.403
2007 Cuadros M, Dave SS, Jaffe ES, Honrado E, Milne R, Alves J, Rodríguez J, Zajac M, Benitez J, Staudt LM, Martinez-Delgado B. Identification of a proliferation signature related to survival in nodal peripheral T-cell lymphomas. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 25: 3321-9. PMID 17577022 DOI: 10.1200/Jco.2006.09.4474  0.454
2007 Kuo TC, Shaffer AL, Haddad J, Choi YS, Staudt LM, Calame K. Repression of BCL-6 is required for the formation of human memory B cells in vitro. The Journal of Experimental Medicine. 204: 819-30. PMID 17403935 DOI: 10.1084/Jem.20062104  0.431
2007 Davis RE, Zhang YQ, Southall N, Staudt LM, Austin CP, Inglese J, Auld DS. A cell-based assay for IkappaBalpha stabilization using a two-color dual luciferase-based sensor. Assay and Drug Development Technologies. 5: 85-103. PMID 17355202 DOI: 10.1089/Adt.2006.048  0.41
2007 Lenz G, Nagel I, Siebert R, Roschke AV, Sanger W, Wright GW, Dave SS, Tan B, Zhao H, Rosenwald A, Muller-Hermelink HK, Gascoyne RD, Campo E, Jaffe ES, Smeland EB, ... ... Staudt LM, et al. Aberrant immunoglobulin class switch recombination and switch translocations in activated B cell-like diffuse large B cell lymphoma. The Journal of Experimental Medicine. 204: 633-43. PMID 17353367 DOI: 10.1182/Blood.V108.11.356.356  0.45
2007 Staudt LM. A closer look at follicular lymphoma. The New England Journal of Medicine. 356: 741-2. PMID 17301308 DOI: 10.1056/Nejmcibr067155  0.365
2007 Wiestner A, Tehrani M, Chiorazzi M, Wright G, Gibellini F, Nakayama K, Liu H, Rosenwald A, Muller-Hermelink HK, Ott G, Chan WC, Greiner TC, Weisenburger DD, Vose J, Armitage JO, ... ... Staudt LM, et al. Point mutations and genomic deletions in CCND1 create stable truncated cyclin D1 mRNAs that are associated with increased proliferation rate and shorter survival. Blood. 109: 4599-606. PMID 17299095 DOI: 10.1182/Blood-2006-08-039859  0.34
2007 Salaverria I, Zettl A, Beà S, Moreno V, Valls J, Hartmann E, Ott G, Wright G, Lopez-Guillermo A, Chan WC, Weisenburger DD, Gascoyne RD, Grogan TM, Delabie J, Jaffe ES, ... ... Staudt LM, et al. Specific secondary genetic alterations in mantle cell lymphoma provide prognostic information independent of the gene expression-based proliferation signature. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 25: 1216-22. PMID 17296973 DOI: 10.1200/Jco.2006.08.4251  0.382
2007 Davies AJ, Rosenwald A, Wright G, Lee A, Last KW, Weisenburger DD, Chan WC, Delabie J, Braziel RM, Campo E, Gascoyne RD, Jaffe ES, Muller-Hermelink K, Ott G, Calaminici M, ... ... Staudt LM, et al. Transformation of follicular lymphoma to diffuse large B-cell lymphoma proceeds by distinct oncogenic mechanisms. British Journal of Haematology. 136: 286-93. PMID 17278262 DOI: 10.1111/j.1365-2141.2006.06439.x  0.336
2007 Schlee M, Hölzel M, Bernard S, Mailhammer R, Schuhmacher M, Reschke J, Eick D, Marinkovic D, Wirth T, Rosenwald A, Staudt LM, Eilers M, Baran-Marszak F, Fagard R, Feuillard J, et al. c-MYC activation impairs the NF-κB and the interferon response: Implications for the pathogenesis of Burkitt's lymphoma International Journal of Cancer. 120: 1387-1395. PMID 17211884 DOI: 10.1002/Ijc.22372  0.441
2007 Dunleavy K, Davis RE, Landgren O, Staudt LM, Wilson WH. BCL-6 and rituximab in diffuse large B-cell lymphoma: where are we? Blood. 109: 843-4; discussion 84. PMID 17210865 DOI: 10.1182/Blood-2006-07-038000  0.413
2007 Lenz G, Davis RE, Ngo VN, Lam LT, George T, Wright GW, Dave SS, Zhao H, Xu W, Rosenwald A, Muller-Hermelink H, Gascoyne RD, Connors JM, Campo E, Jaffe ES, ... ... Staudt LM, et al. CARD11 as an Oncogene in Diffuse Large B Cell Lymphoma. Blood. 110: 692-692. DOI: 10.1182/Blood.V110.11.692.692  0.469
2007 Lenz G, Wright G, Dave S, Kohlmann A, Xiao W, Powell J, Zhao H, Xu W, Gascoyne RD, Connors JM, May L, Weisenburger DD, Greiner T, Vose J, Armitage JO, ... ... Staudt LM, et al. Gene Expression Signatures Predict Overall Survial in Diffuse Large B Cell Lymphoma Treated with Rituximab and Chop-Like Chemotherapy. Blood. 110: 348-348. DOI: 10.1182/Blood.V110.11.348.348  0.432
2007 Lenz G, Wright GW, Dave S, Xiao W, Powell J, Rosenwald A, Muller-Hermelink H, Gascoyne RD, Connors JM, Campo E, Jaffe ES, Delabie J, Smeland EB, Rimsza L, Fisher RI, ... ... Staudt LM, et al. Distinct Genetic Aberrations in Molecular Subtypes of Diffuse Large B Cell Lymphoma Detected by Array CGH. Blood. 110: 2631-2631. DOI: 10.1182/Blood.V110.11.2631.2631  0.491
2006 Mestre-Escorihuela C, Rubio-Moscardo F, Richter JA, Siebert R, Climent J, Fresquet V, Beltran E, Agirre X, Marugan I, Marín M, Rosenwald A, Sugimoto KJ, Wheat LM, Karran EL, García JF, ... ... Staudt LM, et al. Homozygous deletions localize novel tumor suppressor genes in B-cell lymphomas. Blood. 109: 271-80. PMID 16960149 DOI: 10.1182/Blood-2006-06-026500  0.511
2006 Sciammas R, Shaffer AL, Schatz JH, Zhao H, Staudt LM, Singh H. Graded expression of interferon regulatory factor-4 coordinates isotype switching with plasma cell differentiation. Immunity. 25: 225-36. PMID 16919487 DOI: 10.1016/J.Immuni.2006.07.009  0.611
2006 Dave SS, Fu K, Wright GW, Lam LT, Kluin P, Boerma EJ, Greiner TC, Weisenburger DD, Rosenwald A, Ott G, Müller-Hermelink HK, Gascoyne RD, Delabie J, Rimsza LM, Braziel RM, ... ... Staudt LM, et al. Molecular diagnosis of Burkitt's lymphoma. The New England Journal of Medicine. 354: 2431-42. PMID 16760443 DOI: 10.1056/Nejmoa055759  0.433
2006 Liu H, Ippolito GC, Wall JK, Niu T, Probst L, Lee BS, Pulford K, Banham AH, Stockwin L, Shaffer AL, Staudt LM, Das C, Dyer MJ, Tucker PW. Functional studies of BCL11A: characterization of the conserved BCL11A-XL splice variant and its interaction with BCL6 in nuclear paraspeckles of germinal center B cells. Molecular Cancer. 5: 18. PMID 16704730 DOI: 10.1186/1476-4598-5-18  0.476
2006 Shaffer AL, Wright G, Yang L, Powell J, Ngo V, Lamy L, Lam LT, Davis RE, Staudt LM. A library of gene expression signatures to illuminate normal and pathological lymphoid biology. Immunological Reviews. 210: 67-85. PMID 16623765 DOI: 10.1111/J.0105-2896.2006.00373.X  0.484
2006 Spence SL, Shaffer AL, Staudt LM, Amde S, Manney S, Terry C, Weisz K, Nissley P. Transformation of late passage insulin-like growth factor-I receptor null mouse embryo fibroblasts by SV40 T antigen. Cancer Research. 66: 4233-9. PMID 16618746 DOI: 10.1158/0008-5472.Can-05-2257  0.325
2006 Ngo VN, Davis RE, Lamy L, Yu X, Zhao H, Lenz G, Lam LT, Dave S, Yang L, Powell J, Staudt LM. A loss-of-function RNA interference screen for molecular targets in cancer. Nature. 441: 106-10. PMID 16572121 DOI: 10.1038/Nature04687  0.49
2006 Roberts RA, Wright G, Rosenwald AR, Jaramillo MA, Grogan TM, Miller TP, Frutiger Y, Chan WC, Gascoyne RD, Ott G, Muller-Hermelink HK, Staudt LM, Rimsza LM. Loss of major histocompatibility class II gene and protein expression in primary mediastinal large B-cell lymphoma is highly coordinated and related to poor patient survival. Blood. 108: 311-8. PMID 16543468 DOI: 10.1182/Blood-2005-11-4742  0.374
2006 Greiner TC, Dasgupta C, Ho VV, Weisenburger DD, Smith LM, Lynch JC, Vose JM, Fu K, Armitage JO, Braziel RM, Campo E, Delabie J, Gascoyne RD, Jaffe ES, Muller-Hermelink HK, ... ... Staudt LM, et al. Mutation and genomic deletion status of ataxia telangiectasia mutated (ATM) and p53 confer specific gene expression profiles in mantle cell lymphoma. Proceedings of the National Academy of Sciences of the United States of America. 103: 2352-7. PMID 16461462 DOI: 10.1073/Pnas.0510441103  0.403
2006 Iqbal J, Neppalli VT, Wright G, Dave BJ, Horsman DE, Rosenwald A, Lynch J, Hans CP, Weisenburger DD, Greiner TC, Gascoyne RD, Campo E, Ott G, Müller-Hermelink HK, Delabie J, ... ... Staudt LM, et al. BCL2 expression is a prognostic marker for the activated B-cell-like type of diffuse large B-cell lymphoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 24: 961-8. PMID 16418494 DOI: 10.1200/Jco.2005.03.4264  0.472
2006 Rimsza LM, Roberts RA, Campo E, Grogan TM, Bea S, Salaverria I, Zettl A, Rosenwald A, Ott G, Muller-Hermelink HK, Delabie J, Fisher RI, Unger JM, Leblanc M, Staudt LM, et al. Loss of major histocompatibility class II expression in non-immune-privileged site diffuse large B-cell lymphoma is highly coordinated and not due to chromosomal deletions. Blood. 107: 1101-7. PMID 16239429 DOI: 10.1182/Blood-2005-04-1510  0.452
2006 Roberts RA, Rimsza LM, Staudt L, Rosenwald A, Chan W, Dave S, Gascoyne RD, Connors JM, Smeland EB, Muller-Hermelink H, Campo E, Jaffe ES, Wilson W, Tan BK, Fisher RI, et al. Gene Expression Differences between Low and High Stage Diffuse Large B Cell Lymphoma (DLBCL). Blood. 108: 809-809. DOI: 10.1182/Blood.V108.11.809.809  0.342
2006 Lenz G, Nagel I, Siebert R, Sanger W, Wright GW, Zhao H, Rosenwald A, Muller-Hermelink H, Gascoyne RD, Campo E, Jaffe ES, Smeland EB, Fisher RI, Kuehl WM, Chan WC, ... Staudt LM, et al. Aberrant Immunoglobulin Class Switch Recombination and Switch Translocations in Activated B Cell-Like Diffuse Large B-Cell Lymphoma. Blood. 108: 356-356. DOI: 10.1182/BLOOD.V108.11.356.356  0.355
2006 Dunleavy K, Pittaluga S, Janik J, Grant N, Shovlin M, Steinberg S, Raffeld M, Staudt L, Jaffe ES, Wilson WH. Primary Mediastinal Large B-Cell Lymphoma (PMBL) Outcome May Be Significantly Improved by the Addition of Rituximab to Dose-Adjusted (DA)-EPOCH and Obviates the Need for Radiation: Results from a Prospective Study of 44 Patients. Blood. 108: 209-209. DOI: 10.1182/Blood.V108.11.209.209  0.303
2006 Wilson WH, Dunleavy K, Pittaluga S, Grant N, Shovlin M, Steinberg S, Raffeld M, Staudt L, Jaffe ES, Janik J. DA-EPOCH-R Is Highly Effective in Both BCL-6+ and BCL-6− Untreated De Novo Diffuse Large B-Cell Lymphoma (DLBCL): Study Update and Analysis of Survival Outcomes for Multiple Biomarkers. Blood. 108: 206-206. DOI: 10.1182/Blood.V108.11.206.206  0.391
2006 Hystad ME, Bo TH, Rian E, Myklebust JH, Sivertsen E, Forfang L, Chiorazzi M, Rosenwald A, Jonassen I, Staudt LM, Smeland EB. Characterization of Early Human B Cell Development by Gene Expression Profiling. Blood. 108: 1352-1352. DOI: 10.1182/Blood.V108.11.1352.1352  0.452
2005 Han SS, Shaffer AL, Peng L, Chung ST, Lim JH, Maeng S, Kim JS, McNeil N, Ried T, Staudt LM, Janz S. Molecular and cytological features of the mouse B-cell lymphoma line iMycEmu-1. Molecular Cancer. 4: 40. PMID 16277667 DOI: 10.1186/1476-4598-4-40  0.496
2005 Fu K, Weisenburger DD, Greiner TC, Dave S, Wright G, Rosenwald A, Chiorazzi M, Iqbal J, Gesk S, Siebert R, De Jong D, Jaffe ES, Wilson WH, Delabie J, Ott G, ... ... Staudt LM, et al. Cyclin D1-negative mantle cell lymphoma: a clinicopathologic study based on gene expression profiling. Blood. 106: 4315-21. PMID 16123218 DOI: 10.1182/Blood-2005-04-1753  0.336
2005 Staudt LM, Dave S. The biology of human lymphoid malignancies revealed by gene expression profiling Advances in Immunology. 87: 163-208. PMID 16102574 DOI: 10.1016/S0065-2776(05)87005-1  0.524
2005 Rubio-Moscardo F, Blesa D, Mestre C, Siebert R, Balasas T, Benito A, Rosenwald A, Climent J, Martinez JI, Schilhabel M, Karran EL, Gesk S, Esteller M, deLeeuw R, Staudt LM, et al. Characterization of 8p21.3 chromosomal deletions in B-cell lymphoma: TRAIL-R1 and TRAIL-R2 as candidate dosage-dependent tumor suppressor genes. Blood. 106: 3214-22. PMID 16051735 DOI: 10.1182/Blood-2005-05-2013  0.42
2005 Bea S, Zettl A, Wright G, Salaverria I, Jehn P, Moreno V, Burek C, Ott G, Puig X, Yang L, Lopez-Guillermo A, Chan WC, Greiner TC, Weisenburger DD, Armitage JO, ... ... Staudt LM, et al. Diffuse large B-cell lymphoma subgroups have distinct genetic profiles that influence tumor biology and improve gene-expression-based survival prediction. Blood. 106: 3183-90. PMID 16046532 DOI: 10.1182/Blood-2005-04-1399  0.46
2005 Mestre C, Rubio-Moscardo F, Rosenwald A, Climent J, Dyer MJ, Staudt L, Pinkel D, Siebert R, Martinez-Climent JA. Homozygous deletion of SOCS1 in primary mediastinal B-cell lymphoma detected by CGH to BAC microarrays. Leukemia. 19: 1082-4. PMID 15815722 DOI: 10.1038/Sj.Leu.2403741  0.433
2005 Lam LT, Davis RE, Pierce J, Hepperle M, Xu Y, Hottelet M, Nong Y, Wen D, Adams J, Dang L, Staudt LM. Small molecule inhibitors of IkappaB kinase are selectively toxic for subgroups of diffuse large B-cell lymphoma defined by gene expression profiling. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 28-40. PMID 15671525  0.386
2005 Dunleavy K, Pittaluga S, Janik J, Grant N, Steinberg S, Staudt L, Jaffe E, Wilson WH. Primary Mediastinal Large B-Cell Lymphoma (PMBL) Outcome Is Significantly Improved by the Addition of Rituximab to Dose Adjusted (DA)-EPOCH and Overcomes the Need for Radiation. Blood. 106: 929-929. DOI: 10.1182/Blood.V106.11.929.929  0.348
2005 Martinez-Delgado B, Bahl M, Cuadros M, Fernandez V, Benitez J, Jaffe ES, Staudt L. Biological Differences in Peripheral T-Cell Lymphomas Identified by DNA Microarrays. Blood. 106: 3012-3012. DOI: 10.1182/Blood.V106.11.3012.3012  0.42
2005 Iqbal J, Greiner TC, Patel K, Ji J, Dave BJ, Horsman DE, Shen Y, Weisenburger DD, Campo E, Rosenwald A, Gascoyne RD, Jaffe ES, Ott G, Delabie J, Rimsza L, ... ... Staudt LM, et al. Distinctive Patterns of BCL6 Molecular Alterations in Different Subsets of Diffuse Large B-Cell Lymphoma and Their Functional Consequences. Blood. 106: 160-160. DOI: 10.1182/Blood.V106.11.160.160  0.366
2004 Ho L, Davis RE, Conne B, Chappuis R, Berczy M, Mhawech P, Staudt LM, Schwaller J. MALT1 and the API2-MALT1 fusion act between CD40 and IKK and confer NF-kappa B-dependent proliferative advantage and resistance against FAS-induced cell death in B cells. Blood. 105: 2891-9. PMID 15598810 DOI: 10.1182/Blood-2004-06-2297  0.468
2004 Dave SS, Wright G, Tan B, Rosenwald A, Gascoyne RD, Chan WC, Fisher RI, Braziel RM, Rimsza LM, Grogan TM, Miller TP, LeBlanc M, Greiner TC, Weisenburger DD, Lynch JC, ... ... Staudt LM, et al. Prediction of survival in follicular lymphoma based on molecular features of tumor-infiltrating immune cells. The New England Journal of Medicine. 351: 2159-69. PMID 15548776 DOI: 10.1056/Nejmoa041869  0.358
2004 Staudt LM. Cancer: negative feedback for B cells. Nature. 431: 919-20. PMID 15496906 DOI: 10.1038/431919A  0.383
2004 Shen Y, Iqbal J, Xiao L, Lynch RC, Rosenwald A, Staudt LM, Sherman S, Dybkaer K, Zhou G, Eudy JD, Delabie J, McKeithan TW, Chan WC. Distinct gene expression profiles in different B-cell compartments in human peripheral lymphoid organs. Bmc Immunology. 5: 20. PMID 15369600 DOI: 10.1186/1471-2172-5-20  0.457
2004 Shaffer AL, Shapiro-Shelef M, Iwakoshi NN, Lee AH, Qian SB, Zhao H, Yu X, Yang L, Tan BK, Rosenwald A, Hurt EM, Petroulakis E, Sonenberg N, Yewdell JW, Calame K, ... ... Staudt LM, et al. XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation. Immunity. 21: 81-93. PMID 15345222 DOI: 10.1016/J.Immuni.2004.06.010  0.622
2004 Tunyaplin C, Shaffer AL, Angelin-Duclos CD, Yu X, Staudt LM, Calame KL. Direct repression of prdm1 by Bcl-6 inhibits plasmacytic differentiation. Journal of Immunology (Baltimore, Md. : 1950). 173: 1158-65. PMID 15240705 DOI: 10.4049/Jimmunol.173.2.1158  0.4
2004 de Leeuw RJ, Davies JJ, Rosenwald A, Bebb G, Gascoyne RD, Dyer MJ, Staudt LM, Martinez-Climent JA, Lam WL. Comprehensive whole genome array CGH profiling of mantle cell lymphoma model genomes. Human Molecular Genetics. 13: 1827-37. PMID 15229187 DOI: 10.1093/Hmg/Ddh195  0.349
2004 Iqbal J, Sanger WG, Horsman DE, Rosenwald A, Pickering DL, Dave B, Dave S, Xiao L, Cao K, Zhu Q, Sherman S, Hans CP, Weisenburger DD, Greiner TC, Gascoyne RD, ... ... Staudt LM, et al. BCL2 translocation defines a unique tumor subset within the germinal center B-cell-like diffuse large B-cell lymphoma. The American Journal of Pathology. 165: 159-66. PMID 15215171 DOI: 10.1016/S0002-9440(10)63284-1  0.443
2004 Rosenwald A, Staudt LM. Gene expression profiling of diffuse large B-cell lymphoma. Leukemia & Lymphoma. S41-7. PMID 15202524 DOI: 10.1080/10428190310001623775  0.522
2004 Weller S, Braun MC, Tan BK, Rosenwald A, Cordier C, Conley ME, Plebani A, Kumararatne DS, Bonnet D, Tournilhac O, Tchernia G, Steiniger B, Staudt LM, Casanova JL, Reynaud CA, et al. Human blood IgM "memory" B cells are circulating splenic marginal zone B cells harboring a prediversified immunoglobulin repertoire. Blood. 104: 3647-54. PMID 15191950 DOI: 10.1182/Blood-2004-01-0346  0.429
2004 Rosenwald A, Chuang EY, Davis RE, Wiestner A, Alizadeh AA, Arthur DC, Mitchell JB, Marti GE, Fowler DH, Wilson WH, Staudt LM. Fludarabine treatment of patients with chronic lymphocytic leukemia induces a p53-dependent gene expression response. Blood. 104: 1428-34. PMID 15138159 DOI: 10.1182/Blood-2003-09-3236  0.426
2004 Cahir-McFarland ED, Carter K, Rosenwald A, Giltnane JM, Henrickson SE, Staudt LM, Kieff E. Role of NF-kappa B in cell survival and transcription of latent membrane protein 1-expressing or Epstein-Barr virus latency III-infected cells. Journal of Virology. 78: 4108-19. PMID 15047827 DOI: 10.1128/Jvi.78.8.4108-4119.2004  0.472
2004 Hurt EM, Wiestner A, Rosenwald A, Shaffer AL, Campo E, Grogan T, Bergsagel PL, Kuehl WM, Staudt LM. Overexpression of c-maf is a frequent oncogenic event in multiple myeloma that promotes proliferation and pathological interactions with bone marrow stroma. Cancer Cell. 5: 191-9. PMID 14998494 DOI: 10.1016/S1535-6108(04)00019-4  0.318
2004 Rimsza LM, Roberts RA, Miller TP, Unger JM, LeBlanc M, Braziel RM, Weisenberger DD, Chan WC, Muller-Hermelink HK, Jaffe ES, Gascoyne RD, Campo E, Fuchs DA, Spier CM, Fisher RI, ... ... Staudt LM, et al. Loss of MHC class II gene and protein expression in diffuse large B-cell lymphoma is related to decreased tumor immunosurveillance and poor patient survival regardless of other prognostic factors: a follow-up study from the Leukemia and Lymphoma Molecular Profiling Project. Blood. 103: 4251-8. PMID 14976040 DOI: 10.1182/Blood-2003-07-2365  0.409
2004 Orchard JA, Ibbotson RE, Davis Z, Wiestner A, Rosenwald A, Thomas PW, Hamblin TJ, Staudt LM, Oscier DG. ZAP-70 expression and prognosis in chronic lymphocytic leukaemia. Lancet. 363: 105-11. PMID 14726163 DOI: 10.1016/S0140-6736(03)15260-9  0.395
2004 Wiestner A, Staudt LM. Towards molecular diagnosis and targeted therapy of lymphoid malignancies. Seminars in Hematology. 40: 296-307. PMID 14582080 DOI: 10.1016/S0037-1963(03)00194-X  0.494
2004 Hans CP, Weisenburger DD, Greiner TC, Gascoyne RD, Delabie J, Ott G, Müller-Hermelink HK, Campo E, Braziel RM, Jaffe ES, Pan Z, Farinha P, Smith LM, Falini B, Banham AH, ... ... Staudt LM, et al. Confirmation of the molecular classification of diffuse large B-cell lymphoma by immunohistochemistry using a tissue microarray. Blood. 103: 275-82. PMID 14504078 DOI: 10.1182/Blood-2003-05-1545  0.43
2004 Wiestner A, Chiorazzi M, Lai R, Rosenwald A, Muller-Hermelink HK, Ott G, Chan WC, Greiner TC, Weisenburger DD, Vose J, Armitage JO, Gascoyne RD, Connors JM, Campo E, Montserrat E, ... ... Staudt LM, et al. High Cyclin D1 Expression Is Associated with Increased Proliferation Rate and Decreased Survival in Mantle Cell Lymphoma (MCL) and Is Caused by Genomic Deletions and Mutations that Enhance Stability of Cyclin D1 mRNA. Blood. 104: 697-697. DOI: 10.1182/Blood.V104.11.697.697  0.368
2004 Zettl A, Bea S, Wright G, Salaverria I, Jehn P, Ott G, Chan W, Jaffe E, Weisenburger D, Greiner T, Armitage J, Gascoyne R, Connors J, Grogan T, Miller T, ... ... Staudt L, et al. Chromosomal Imbalances in Germinal Center B-Cell-Like and Activated B-Cell-Like Diffuse Large B-Cell Lymphoma Influence Gene Expression Signatures and Improve Gene Expression-Based Survival Prediction(the First Two Authors Contributed Equally to This Work). Blood. 104: 415-415. DOI: 10.1182/Blood.V104.11.415.415  0.425
2004 Lee A, Davies A, Clear A, Calaminici M, Matthews J, Norton A, Wright G, Staudt LM, Fitzgibbon J, Lister TA, Goff L. Tissue Microarray Is a Useful Tool in the Evaluation of Genes Implicated in Transformation of Follicular Lymphoma. Blood. 104: 2267-2267. DOI: 10.1182/Blood.V104.11.2267.2267  0.349
2004 Wilson WH, Dunleavy K, Pittaluga S, Grant N, Steinberg S, Raffeld M, Chabner B, Grossbard M, Jaffe E, Staudt L, Janik J. Dose-Adjusted EPOCH-Rituximab Is Highly Effective in the GCB and ABC Subtypes of Untreated Diffuse Large B-Cell Lymphoma. Blood. 104: 159-159. DOI: 10.1182/Blood.V104.11.159.159  0.383
2004 Zettl A, Bea S, Rosenwald A, Jehn P, Salaverria I, Ott G, Staudt L, Müller-Hermelink H, Campo E. Germinal center B-cell-like and activated B-cell like diffuse large B-cell lymphoma are genetically distinct Pathology - Research and Practice. 200: 343. DOI: 10.1016/S0344-0338(04)80725-8  0.331
2003 McConnell MJ, Chevallier N, Berkofsky-Fessler W, Giltnane JM, Malani RB, Staudt LM, Licht JD. Growth suppression by acute promyelocytic leukemia-associated protein PLZF is mediated by repression of c-myc expression. Molecular and Cellular Biology. 23: 9375-88. PMID 14645547 DOI: 10.1128/Mcb.23.24.9375-9388.2003  0.391
2003 Rosenwald A, Wright G, Leroy K, Yu X, Gaulard P, Gascoyne RD, Chan WC, Zhao T, Haioun C, Greiner TC, Weisenburger DD, Lynch JC, Vose J, Armitage JO, Smeland EB, ... ... Staudt LM, et al. Molecular diagnosis of primary mediastinal B cell lymphoma identifies a clinically favorable subgroup of diffuse large B cell lymphoma related to Hodgkin lymphoma. The Journal of Experimental Medicine. 198: 851-62. PMID 12975453 DOI: 10.1084/Jem.20031074  0.506
2003 Wright G, Tan B, Rosenwald A, Hurt EH, Wiestner A, Staudt LM. A gene expression-based method to diagnose clinically distinct subgroups of diffuse large B cell lymphoma. Proceedings of the National Academy of Sciences of the United States of America. 100: 9991-6. PMID 12900505 DOI: 10.1073/Pnas.1732008100  0.49
2003 Pan Z, Shen Y, Du C, Zhou G, Rosenwald A, Staudt LM, Greiner TC, McKeithan TW, Chan WC. Two newly characterized germinal center B-cell-associated genes, GCET1 and GCET2, have differential expression in normal and neoplastic B cells. The American Journal of Pathology. 163: 135-44. PMID 12819018 DOI: 10.1016/S0002-9440(10)63637-1  0.514
2003 Staudt LM. Molecular diagnosis of the hematologic cancers. The New England Journal of Medicine. 348: 1777-85. PMID 12724484 DOI: 10.1056/Nejmra020067  0.357
2003 Rosenwald A, Wright G, Wiestner A, Chan WC, Connors JM, Campo E, Gascoyne RD, Grogan TM, Muller-Hermelink HK, Smeland EB, Chiorazzi M, Giltnane JM, Hurt EM, Zhao H, Averett L, ... ... Staudt LM, et al. The proliferation gene expression signature is a quantitative integrator of oncogenic events that predicts survival in mantle cell lymphoma. Cancer Cell. 3: 185-97. PMID 12620412 DOI: 10.1016/S1535-6108(03)00028-X  0.45
2003 Wiestner A, Rosenwald A, Barry TS, Wright G, Davis RE, Henrickson SE, Zhao H, Ibbotson RE, Orchard JA, Davis Z, Stetler-Stevenson M, Raffeld M, Arthur DC, Marti GE, Wilson WH, ... ... Staudt LM, et al. ZAP-70 expression identifies a chronic lymphocytic leukemia subtype with unmutated immunoglobulin genes, inferior clinical outcome, and distinct gene expression profile. Blood. 101: 4944-51. PMID 12595313 DOI: 10.1182/Blood-2002-10-3306  0.401
2003 Nasr R, Rosenwald A, El-Sabban ME, Arnulf B, Zalloua P, Lepelletier Y, Bex F, Hermine O, Staudt L, de Thé H, Bazarbachi A. Arsenic/interferon specifically reverses 2 distinct gene networks critical for the survival of HTLV-1-infected leukemic cells. Blood. 101: 4576-82. PMID 12560223 DOI: 10.1182/Blood-2002-09-2986  0.432
2003 Sanchez-Izquierdo D, Buchonnet G, Siebert R, Gascoyne RD, Climent J, Karran L, Marin M, Blesa D, Horsman D, Rosenwald A, Staudt LM, Albertson DG, Du MQ, Ye H, Marynen P, et al. MALT1 is deregulated by both chromosomal translocation and amplification in B-cell non-Hodgkin lymphoma. Blood. 101: 4539-46. PMID 12560219 DOI: 10.1182/Blood-2002-10-3236  0.445
2003 Shaffer AL, Rosenwald A, Staudt LM. Lymphoid malignancies: the dark side of B-cell differentiation. Nature Reviews. Immunology. 2: 920-32. PMID 12461565 DOI: 10.1038/Nri953  0.479
2003 Staudt LM, Wilson WH. Focus on lymphomas. Cancer Cell. 2: 363-6. PMID 12450791 DOI: 10.1016/S1535-6108(02)00178-2  0.375
2002 Kalaitzidis D, Davis RE, Rosenwald A, Staudt LM, Gilmore TD. The human B-cell lymphoma cell line RC-K8 has multiple genetic alterations that dysregulate the Rel/NF-kappaB signal transduction pathway. Oncogene. 21: 8759-68. PMID 12483529 DOI: 10.1038/Sj.Onc.1206033  0.411
2002 Shaffer AL, Lin KI, Kuo TC, Yu X, Hurt EM, Rosenwald A, Giltnane JM, Yang L, Zhao H, Calame K, Staudt LM. Blimp-1 orchestrates plasma cell differentiation by extinguishing the mature B cell gene expression program. Immunity. 17: 51-62. PMID 12150891 DOI: 10.1016/S1074-7613(02)00335-7  0.495
2002 Staudt LM. It's ALL in the diagnosis. Cancer Cell. 1: 109-10. PMID 12086866 DOI: 10.1016/S1535-6108(02)00036-3  0.345
2002 Rosenwald A, Wright G, Chan WC, Connors JM, Campo E, Fisher RI, Gascoyne RD, Muller-Hermelink HK, Smeland EB, Giltnane JM, Hurt EM, Zhao H, Averett L, Yang L, Wilson WH, ... ... Staudt LM, et al. The use of molecular profiling to predict survival after chemotherapy for diffuse large-B-cell lymphoma. The New England Journal of Medicine. 346: 1937-47. PMID 12075054 DOI: 10.1056/Nejmoa012914  0.499
2002 Rosenwald A, Staudt LM. Clinical translation of gene expression profiling in lymphomas and leukemias. Seminars in Oncology. 29: 258-63. PMID 12063678 DOI: 10.1053/Sonc.2002.32901  0.472
2002 Davis RE, Staudt LM. Molecular diagnosis of lymphoid malignancies by gene expression profiling. Current Opinion in Hematology. 9: 333-8. PMID 12042708 DOI: 10.1097/00062752-200207000-00011  0.487
2002 Wilson WH, Grossbard ML, Pittaluga S, Cole D, Pearson D, Drbohlav N, Steinberg SM, Little RF, Janik JE, Gutierrez M, Raffeld M, Staudt L, Cheson BD, Longo DL, Harris N, et al. Dose-adjusted EPOCH chemotherapy for untreated large B-cell lymphomas: a pharmacodynamic approach with high efficacy Blood. 99: 2685-2693. PMID 11929754 DOI: 10.1182/Blood.V99.8.2685  0.369
2002 Huang JZ, Sanger WG, Greiner TC, Staudt LM, Weisenburger DD, Pickering DL, Lynch JC, Armitage JO, Warnke RA, Alizadeh AA, Lossos IS, Levy R, Chan WC. The t(14;18) defines a unique subset of diffuse large B-cell lymphoma with a germinal center B-cell gene expression profile. Blood. 99: 2285-90. PMID 11895757 DOI: 10.1182/Blood.V99.7.2285  0.465
2002 Staudt LM. Gene expression profiling of lymphoid malignancies. Annual Review of Medicine. 53: 303-18. PMID 11818476 DOI: 10.1146/Annurev.Med.53.082901.103941  0.479
2002 Boldrick JC, Alizadeh AA, Diehn M, Dudoit S, Liu CL, Belcher CE, Botstein D, Staudt LM, Brown PO, Relman DA. Stereotyped and specific gene expression programs in human innate immune responses to bacteria. Proceedings of the National Academy of Sciences of the United States of America. 99: 972-7. PMID 11805339 DOI: 10.1073/Pnas.231625398  0.311
2002 van der Pouw Kraan T, van Gaalen F, Kasperkovitz P, Verbeet N, Alizadeh A, Fero M, Huizinga T, Pieterman E, Breedveld F, Staudt L, Botstein D, Brown P, Verweij C. Arthritis Research. 4: 28. DOI: 10.1186/Ar468  0.356
2001 Davis RE, Brown KD, Siebenlist U, Staudt LM. Constitutive nuclear factor kappaB activity is required for survival of activated B cell-like diffuse large B cell lymphoma cells. The Journal of Experimental Medicine. 194: 1861-74. PMID 11748286 DOI: 10.1084/Jem.194.12.1861  0.518
2001 Rosenwald A, Alizadeh AA, Widhopf G, Simon R, Davis RE, Yu X, Yang L, Pickeral OK, Rassenti LZ, Powell J, Botstein D, Byrd JC, Grever MR, Cheson BD, Chiorazzi N, ... ... Staudt LM, et al. Relation of gene expression phenotype to immunoglobulin mutation genotype in B cell chronic lymphocytic leukemia. The Journal of Experimental Medicine. 194: 1639-47. PMID 11733578 DOI: 10.1084/Jem.194.11.1639  0.485
2001 Shaffer AL, Rosenwald A, Hurt EM, Giltnane JM, Lam LT, Pickeral OK, Staudt LM. Signatures of the immune response Immunity. 15: 375-385. PMID 11567628 DOI: 10.1016/S1074-7613(01)00194-7  0.491
2001 Siebert R, Rosenwald A, Staudt LM, Morris SW. Molecular features of B-cell lymphoma. Current Opinion in Oncology. 13: 316-24. PMID 11555707 DOI: 10.1097/00001622-200109000-00002  0.465
2001 Boehm J, He Y, Greiner A, Staudt L, Wirth T. Regulation of BOB.1/OBF.1 stability by SIAH. The Embo Journal. 20: 4153-62. PMID 11483518 DOI: 10.1093/Emboj/20.15.4153  0.76
2001 Staudt LM. Gene expression physiology and pathophysiology of the immune system. Trends in Immunology. 22: 35-40. PMID 11286690 DOI: 10.1016/S1471-4906(00)01792-0  0.377
2001 Feske S, Giltnane J, Dolmetsch R, Staudt LM, Rao A. Gene regulation mediated by calcium signals in T lymphocytes Nature Immunology. 2: 316-324. PMID 11276202 DOI: 10.1038/86318  0.408
2001 Ma C, Staudt LM. Molecular definition of the germinal centre stage of B-cell differentiation. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 356: 83-9. PMID 11205335 DOI: 10.1098/Rstb.2000.0752  0.475
2000 Hastie T, Tibshirani R, Eisen MB, Alizadeh A, Levy R, Staudt L, Chan WC, Botstein D, Brown P. 'Gene shaving' as a method for identifying distinct sets of genes with similar expression patterns. Genome Biology. 1: RESEARCH0003. PMID 11178228 DOI: 10.1186/Gb-2000-1-2-Research0003  0.362
2000 Shaffer AL, Yu X, He Y, Boldrick J, Chan EP, Staudt LM. BCL-6 represses genes that function in lymphocyte differentiation, inflammation, and cell cycle control. Immunity. 13: 199-212. PMID 10981963 DOI: 10.1016/S1074-7613(00)00020-0  0.784
2000 Meffre E, Davis E, Schiff C, Cunningham-Rundles C, Ivashkiv LB, Staudt LM, Young JW, Nussenzweig MC. Circulating human B cells that express surrogate light chains and edited receptors. Nature Immunology. 1: 207-13. PMID 10973277 DOI: 10.1038/79739  0.418
2000 Lossos IS, Alizadeh AA, Eisen MB, Chan WC, Brown PO, Botstein D, Staudt LM, Levy R. Ongoing immunoglobulin somatic mutation in germinal center B cell-like but not in activated B cell-like diffuse large cell lymphomas. Proceedings of the National Academy of Sciences of the United States of America. 97: 10209-13. PMID 10954754 DOI: 10.1073/Pnas.180316097  0.511
2000 Staudt LM, Brown PO. Genomic views of the immune system Annual Review of Immunology. 18: 829-859. PMID 10837077 DOI: 10.1146/Annurev.Immunol.18.1.829  0.388
2000 Alizadeh AA, Staudt LM. Genomic-scale gene expression profiling of normal and malignant immune cells. Current Opinion in Immunology. 12: 219-25. PMID 10712950 DOI: 10.1016/S0952-7915(99)00078-3  0.423
2000 Alizadeh AA, Eisen MB, Davis RE, Ma C, Lossos IS, Rosenwald A, Boldrick JC, Sabet H, Tran T, Yu X, Powell JI, Yang L, Marti GE, Moore T, Hudson J, ... ... Staudt LM, et al. Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature. 403: 503-11. PMID 10676951 DOI: 10.1038/35000501  0.507
2000 Staudt LM, Dent AL, Shaffer AL, Yu X. Regulation of lymphocyte cell fate decisions and lymphomagenesis by BCL-6. International Reviews of Immunology. 18: 381-403. PMID 10626250 DOI: 10.3109/08830189909088490  0.489
1999 Alizadeh A, Eisen M, Davis RE, Ma C, Sabet H, Tran T, Powell JI, Yang L, Marti GE, Moore DT, Hudson JR, Chan WC, Greiner T, Weisenburger D, Armitage JO, ... ... Staudt LM, et al. The lymphochip: a specialized cDNA microarray for the genomic-scale analysis of gene expression in normal and malignant lymphocytes. Cold Spring Harbor Symposia On Quantitative Biology. 64: 71-8. PMID 11232339 DOI: 10.1101/Sqb.1999.64.71  0.356
1999 Iyer VR, Eisen MB, Ross DT, Schuler G, Moore T, Lee JC, Trent JM, Staudt LM, Hudson J, Boguski MS, Lashkari D, Shalon D, Botstein D, Brown PO. The transcriptional program in the response of human fibroblasts to serum. Science (New York, N.Y.). 283: 83-7. PMID 9872747 DOI: 10.1126/Science.283.5398.83  0.312
1999 Cossman J, Annunziata CM, Barash S, Staudt L, Dillon P, He W, Ricciardi-Castagnoli P, Rosen CA, Carter KC. Reed-Sternberg Cell Genome Expression Supports a B-Cell Lineage Blood. 94: 411-416. DOI: 10.1182/Blood.V94.2.411.414K47_411_416  0.469
1999 Cossman J, Annunziata CM, Barash S, Staudt L, Dillon P, He W, Ricciardi-Castagnoli P, Rosen CA, Carter KC. Reed-Sternberg Cell Genome Expression Supports a B-Cell Lineage Blood. 94: 411-416. DOI: 10.1182/blood.V94.2.411  0.365
1999 Yang L, Powell J, Alizadeh A, Davis RE, Ma C, Sabet H, Tran T, Staudt LM. Building lymphochip-computational algorithms for selecting clones highly expressed in B cell cDNA libraries Nature Genetics. 23: 83-83. DOI: 10.1038/14431  0.352
1999 Cossman J, Vockley J, Carter K, Ruben S, Staudt L, Barash S, Birse C, Rosen C, Dolginow D, Lennon G. Genome-wide gene expression of the rare, malignant Reed-Sternberg cellof Hodgkin lymphoma Nature Genetics. 23: 40-40. DOI: 10.1038/14289  0.466
1999 Alizadeh A, Eisen MB, Davis RE, Powell JI, Yang L, Hart RR, Sabet H, Tran TH, Yu X, Ma C, Chan WC, Greiner TC, Weisenburger DD, Armitage JO, Lossos I, ... ... Staudt LM, et al. Analysis of gene expression in normal and malignant lymphocytes using the Lymphochip cDNA microarray Nature Genetics. 23: 30-31. DOI: 10.1038/14260  0.384
1999 Staudt LM. Analysis of gene expression in lymphoid malignancies using the Lymphochip cDNA microarray Nature Genetics. 23: 22-22. DOI: 10.1038/14242  0.377
1998 Alizadeh A, Eisen M, Botstein D, Brown PO, Staudt LM. Probing lymphocyte biology by genomic-scale gene expression analysis Journal of Clinical Immunology. 18: 373-379. PMID 9857281 DOI: 10.1023/A:1023293621057  0.438
1998 Dent AL, Hu-Li J, Paul WE, Staudt LM. T helper type 2 inflammatory disease in the absence of interleukin 4 and transcription factor STAT6. Proceedings of the National Academy of Sciences of the United States of America. 95: 13823-8. PMID 9811885 DOI: 10.1073/Pnas.95.23.13823  0.317
1997 Yin L, Schwartzberg P, Scharton-kerstenj TM, Staudt L, Lenardo M. Immune responses in mice deficient in Ly-GDI, a lymphoid-specific regulator of Rho GTPases Molecular Immunology. 34: 481-491. PMID 9307064 DOI: 10.1016/S0161-5890(97)00053-9  0.377
1997 Dent AL, Shaffer AL, Yu X, Allman D, Staudt LM. Control of inflammation, cytokine expression, and germinal center formation by BCL-6. Science (New York, N.Y.). 276: 589-92. PMID 9110977 DOI: 10.1126/Science.276.5312.589  0.406
1996 Behrens TW, Kearns GM, Rivard JJ, Bernstein HD, Yewdell JW, Staudt LM. Carboxyl-terminal targeting and novel post-translational processing of JAW1, a lymphoid protein of the endoplasmic reticulum Journal of Biological Chemistry. 271: 23528-23534. PMID 8798562 DOI: 10.1074/Jbc.271.38.23528  0.468
1996 Vigano MA, Staudt LM. Transcriptional activation by Oct-3: evidence for a specific role of the POU-specific domain in mediating functional interaction with Oct-1. Nucleic Acids Research. 24: 2112-8. PMID 8668543 DOI: 10.1093/Nar/24.11.2112  0.344
1996 Seyfert VL, Allman D, He Y, Staudt LM. Transcriptional repression by the proto-oncogene BCL-6. Oncogene. 12: 2331-42. PMID 8649773  0.726
1996 Dent A, Yewdell J, Puvion-Dutilleul F, Koken M, de The H, Staudt L. LYSP100-associated nuclear domains (LANDs): description of a new class of subnuclear structures and their relationship to PML nuclear bodies Blood. 88: 1423-1426. DOI: 10.1182/Blood.V88.4.1423.Bloodjournal8841423  0.519
1996 Ma C, Staudt L. LAF-4 encodes a lymphoid nuclear protein with transactivation potential that is homologous to AF-4, the gene fused to MLL in t(4;11) leukemias Blood. 87: 734-745. DOI: 10.1182/Blood.V87.2.734.Bloodjournal872734  0.409
1996 Allman D, Jain A, Dent A, Maile R, Selvaggi T, Kehry M, Staudt L. BCL-6 expression during B-cell activation Blood. 87: 5257-5268. DOI: 10.1182/Blood.V87.12.5257.Bloodjournal87125257  0.45
1995 Staudt LM, Dent A, Ma C, Allman D, Powell J, Maile R, Scherle P, Behrens T. Rapid identification of novel human lymphoid-restricted genes by automated DNA sequencing of subtracted cDNA libraries. Current Topics in Microbiology and Immunology. 194: 155-61. PMID 7895489 DOI: 10.1007/978-3-642-79275-5_19  0.45
1993 Scherle P, Behrens T, Staudt LM. Ly-GDI, a GDP-dissociation inhibitor of the RhoA GTP-binding protein, is expressed preferentially in lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. 90: 7568-72. PMID 8356058 DOI: 10.1073/Pnas.90.16.7568  0.391
1992 Kang SM, Tsang W, Doll S, Scherle P, Ko HS, Tran AC, Lenardo MJ, Staudt LM. Induction of the POU domain transcription factor Oct-2 during T-cell activation by cognate antigen. Molecular and Cellular Biology. 12: 3149-54. PMID 1620122 DOI: 10.1128/Mcb.12.7.3149  0.398
1991 Kavaler J, Caton AJ, Staudt LM, Gerhard W. A B cell population that dominates the primary response to influenza virus hemagglutinin does not participate in the memory response. European Journal of Immunology. 21: 2687-95. PMID 1936117 DOI: 10.1002/Eji.1830211107  0.663
1991 Staudt LM, Lenardo MJ. Immunoglobulin gene transcription. Annual Review of Immunology. 9: 373-98. PMID 1910683 DOI: 10.1146/Annurev.Iy.09.040191.002105  0.401
1991 Caton AJ, Stark SE, Kavaler J, Staudt LM, Schwartz D, Gerhard W. Many variable region genes are utilized in the antibody response of BALB/c mice to the influenza virus A/PR/8/34 hemagglutinin. Journal of Immunology (Baltimore, Md. : 1950). 147: 1675-86. PMID 1908881  0.599
1990 Clarke S, Rickert R, Wloch MK, Staudt L, Gerhard W, Weigert M. The BALB/c secondary response to the Sb site of influenza virus hemagglutinin: Nonrandom silent mutation and unequal numbers of VH and Vk mutations Journal of Immunology. 145: 2286-2296. PMID 2398280  0.609
1990 Kavaler J, Caton AJ, Staudt LM, Schwartz D, Gerhard W. A set of closely related antibodies dominates the primary antibody response to the antigenic site CB of the A/PR/8/34 influenza virus hemagglutinin. Journal of Immunology (Baltimore, Md. : 1950). 145: 2312-21. PMID 2118933  0.604
1990 Clarke SH, Staudt LM, Kavaler J, Schwartz D, Gerhard WU, Weigert MG. V region gene usage and somatic mutation in the primary and secondary responses to influenza virus hemagglutinin. Journal of Immunology (Baltimore, Md. : 1950). 144: 2795-801. PMID 2108213  0.588
1990 Rosner MH, Vigano MA, Ozato K, Timmons PM, Poirier F, Rigby PW, Staudt LM. A POU-domain transcription factor in early stem cells and germ cells of the mammalian embryo. Nature. 345: 686-92. PMID 1972777 DOI: 10.1038/345686A0  0.397
1990 Petryniak B, Staudt LM, Postema CE, McCormack WT, Thompson CB. Characterization of chicken octamer-binding proteins demonstrates that POU domain-containing homeobox transcription factors have been highly conserved during vertebrate evolution. Proceedings of the National Academy of Sciences of the United States of America. 87: 1099-103. PMID 1967834 DOI: 10.1073/Pnas.87.3.1099  0.363
1989 Lenardo MJ, Staudt L, Robbins P, Kuang A, Mulligan RC, Baltimore D. Repression of the IgH enhancer in teratocarcinoma cells associated with a novel octamer factor. Science (New York, N.Y.). 243: 544-6. PMID 2536195 DOI: 10.1126/Science.2536195  0.636
1988 Staudt LM, Clerc RG, Singh H, LeBowitz JH, Sharp PA, Baltimore D. Cloning of a lymphoid-specific cDNA encoding a protein binding the regulatory octamer DNA motif Science. 241: 577-580. PMID 3399892 DOI: 10.1126/Science.3399892  0.664
1988 LeBowitz JH, Kobayashi T, Staudt L, Baltimore D, Sharp PA. Octamer-binding proteins from B or HeLa cells stimulate transcription of the immunoglobulin heavy-chain promoter in vitro Genes &Amp; Development. 2: 1227-1237. PMID 3264542 DOI: 10.1101/Gad.2.10.1227  0.518
1987 Wirth T, Staudt L, Baltimore D. An octamer oligonucleotide upstream of a TATA motif is sufficient for lymphoid-specific promoter activity. Nature. 329: 174-8. PMID 3627254 DOI: 10.1038/329174A0  0.493
1986 Staudt LM, Singh H, Sen R, Wirth T, Sharp PA, Baltimore D. A lymphoid-specific protein binding to the octamer motif of immunoglobulin genes. Nature. 323: 640-3. PMID 3095662 DOI: 10.1038/323640A0  0.588
1986 Caton AJ, Brownlee GG, Staudt LM, Gerhard W. Structural and functional implications of a restricted antibody response to a defined antigenic region on the influenza virus hemagglutinin. The Embo Journal. 5: 1577-87. PMID 2427335 DOI: 10.1002/J.1460-2075.1986.Tb04399.X  0.618
1985 Clarke SH, Huppi K, Ruezinsky D, Staudt L, Gerhard W, Weigert M. Inter- and intraclonal diversity in the antibody response to influenza hemagglutinin Journal of Experimental Medicine. 161: 687-704. PMID 3920342 DOI: 10.1084/Jem.161.4.687  0.616
1984 Huppi K, Julius M, Staudt L, Gerhard W, Weigert M. The idiotypes of Vκ21 light chains Annales De L'Institut Pasteur/Actualites. 135: 181-185. PMID 6424552 DOI: 10.1016/S0769-2625(84)80030-6  0.555
1984 McKean D, Huppi K, Bell M, Staudt L, Gerhard W, Weigert M. Generation of antibody diversity in the immune response of BALB/c mice to influenza virus hemagglutinin Proceedings of the National Academy of Sciences of the United States of America. 81: 3180-3184. PMID 6203114 DOI: 10.1073/Pnas.81.10.3180  0.607
1983 Staudt LM, Gerhard W. Generation of antibody diversity in the immune response of BALB/c mice to influenza virus hemagglutinin. I. Significant variation in repertoire expression between individual mice. The Journal of Experimental Medicine. 157: 687-704. PMID 6600489 DOI: 10.1084/Jem.157.2.687  0.587
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