115 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Xu J, Liu JL, Medeiros LJ, Huang W, Khoury JD, McDonnell TJ, Tang G, Schlette E, Yin CC, Bueso-Ramos CE, Lin P, Li S. MYC Rearrangement and MYC/BCL2 Double Expression but not Cell-of-Origin Predict Prognosis in R-CHOP-Treated Diffuse Large B Cell Lymphoma. European Journal of Haematology. PMID 31944390 DOI: 10.1111/Ejh.13384  0.385
2019 Westin JR, Nastoupil LJ, Fayad L, Hagemeister FB, Oki Y, Turturro F, Ahmed S, Rodriguez MA, Lee HJ, Steiner RE, Nair R, Parmar S, Young KH, McDonnell TJ, Chuang H, et al. Smart Start: Rituximab, Lenalidomide, and Ibrutinib Alone and in Combination with Standard Chemotherapy for Patients with Newly Diagnosed Diffuse Large B-Cell Lymphoma: Final Phase II Results Blood. 134: 1581-1581. DOI: 10.1182/Blood-2019-128475  0.307
2016 Ishizawa J, Kojima K, Chachad D, Ruvolo P, Ruvolo V, Jacamo RO, Borthakur G, Mu H, Zeng Z, Tabe Y, Allen JE, Wang Z, Ma W, Lee HC, Orlowski R, ... ... McDonnell T, et al. ATF4 induction through an atypical integrated stress response to ONC201 triggers p53-independent apoptosis in hematological malignancies. Science Signaling. 9: ra17. PMID 26884599 DOI: 10.1126/Scisignal.Aac4380  0.531
2016 Westin JR, Oki Y, Fayad L, Nastoupil LJ, Turturro F, Hagemeister FB, Sathyanarayanan V, Young KH, McDonnell T, Chuang H, Zhou S, Neelapu SS, Davis RE. Rituximab, lenalidomide, and ibrutinib alone and combined with dose adjusted chemotherapy for patients with high risk diffuse large B-cell lymphoma. Journal of Clinical Oncology. 34: TPS7575-TPS7575. DOI: 10.1200/Jco.2016.34.15_Suppl.Tps7575  0.32
2016 Issa A, Sathyanarayanan V, Fanale MA, Oki Y, Hagemeister FB, Neelapu SS, Nastoupil LJ, Fowler NH, Turturro F, Noorani M, Ahmed MA, Davis RE, Rodriguez MA, Wang M, Feng L, ... ... McDonnell T, et al. Outcomes of diffuse large b-cell lymphoma with MYC and/or BCL2 protein expression treated with intensive chemotherapy. Journal of Clinical Oncology. 34: 7563-7563. DOI: 10.1200/Jco.2016.34.15_Suppl.7563  0.36
2015 Xu-Monette ZY, Dabaja BS, Wang X, Tu M, Manyam GC, Tzankov A, Xia Y, Zhang L, Sun R, Visco C, Dybkaer K, Yin L, Chiu A, Orazi A, Zu Y, ... ... McDonnell TJ, et al. Clinical features, tumor biology, and prognosis associated with MYC rearrangement and Myc overexpression in diffuse large B-cell lymphoma patients treated with rituximab-CHOP. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 26541272 DOI: 10.1038/Modpathol.2015.118  0.415
2015 Teo AE, Chen Z, Miranda RN, McDonnell T, Medeiros LJ, McCarty N. Differential PAX5 levels promote malignant B cell, infiltration, progression and drug resistance and, predict a poor prognosis in MCL patients independent, of CCND1. Leukemia. PMID 26073757 DOI: 10.1038/Leu.2015.140  0.325
2015 Ishizawa J, Kojima K, Chachad D, Ruvolo P, Ruvolo V, Jacamo RO, Borthakur G, Mu H, Zeng Z, Tabe Y, Allen J, Wang Z, Ma W, Lee H, Orlowski RZ, ... ... McDonnell TJ, et al. ONC201 Induces p53-Independent Apoptosis and Abrogates Stem Cell Function in Hematological Malignancies By Induction of ATF4 through Integrated Stress Response Blood. 126: 2051-2051. DOI: 10.1182/Blood.V126.23.2051.2051  0.506
2015 Ishizawa J, Kojima K, Chachad D, Ruvolo P, Ruvolo V, Jacamo RO, Borthakur G, Mu H, Zeng Z, Tabe Y, Allen JE, Wang Z, Ma W, Lee HC, Orlowski R, ... ... McDonnell T, et al. First-in-class Anti-tumor Agent ONC201 Induces Apoptosis in Hematological Malignancies with Wild Type and Mutant p53 Clinical Lymphoma Myeloma and Leukemia. 15: S73. DOI: 10.1016/J.Clml.2015.07.149  0.305
2014 Yoshimura M, Ishizawa J, Ruvolo V, Dilip A, Quintás-Cardama A, McDonnell TJ, Neelapu SS, Kwak LW, Shacham S, Kauffman M, Tabe Y, Yokoo M, Kimura S, Andreeff M, Kojima K. Induction of p53-mediated transcription and apoptosis by exportin-1 (XPO1) inhibition in mantle cell lymphoma. Cancer Science. 105: 795-801. PMID 24766216 DOI: 10.1111/Cas.12430  0.538
2014 Tzankov A, Xu-Monette ZY, Gerhard M, Visco C, Dirnhofer S, Gisin N, Dybkaer K, Orazi A, Bhagat G, Richards KL, Hsi ED, Choi WW, van Krieken JH, Ponzoni M, Ferreri AJ, ... ... McDonnell T, et al. Rearrangements of MYC gene facilitate risk stratification in diffuse large B-cell lymphoma patients treated with rituximab-CHOP. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 27: 958-71. PMID 24336156 DOI: 10.1038/Modpathol.2013.214  0.388
2014 Ishizawa J, Kojima K, Chachad D, Ruvolo PP, Ruvolo VR, Jacamo R, Dilip A, Mu H, Zeng Z, Matre P, Allen JE, Neelapu SS, McDonnell TJ, Miranda RN, Kwak LW, et al. ONC201 Induces p53-Independent Apoptosis and Cell Cycle Arrest in Hematological Malignancies and Leukemic Stem/Progenitor Cells By Inducing ER Stress and mTOR Inhibition Blood. 124: 3122-3122. DOI: 10.1182/Blood.V124.21.3122.3122  0.516
2013 Chari NS, Romano RA, Koster MI, Jaks V, Roop D, Flores ER, Teglund S, Sinha S, Gruber W, Aberger F, Medeiros LJ, Toftgard R, McDonnell TJ. Interaction between the TP63 and SHH pathways is an important determinant of epidermal homeostasis. Cell Death and Differentiation. 20: 1080-8. PMID 23686138 DOI: 10.1038/Cdd.2013.41  0.394
2013 Ishizawa J, Kojima K, Dilip A, Ruvolo VR, Carter BZ, Allen JE, Neelapu SS, McDonnell TJ, Talekar MK, El-Deiry WS, Kwak LW, Andreeff M. ONC201 Exerts p53-Independent Cytotoxicity Through TRAIL and DR5 Induction In Mantle Cell Lymphomas Blood. 122: 3822-3822. DOI: 10.1182/Blood.V122.21.3822.3822  0.52
2013 Xu-Monette ZY, Dabaja BS, Tzankov A, Visco C, Miranda RN, Dybkaer K, Chiu A, Orazi A, Zu Y, Bhagat G, Richards KL, Hsi ED, Choi WL, Krieken JHJMV, Huh J, ... ... McDonnell TJ, et al. Radiation Therapy Significantly Improves Survival Of Patients With Diffuse Large B-Cell Lymphoma Associated With MYC Translocation: A Report From The International DLBCL Rituximab-CHOP Consortium Program Blood. 122: 213-213. DOI: 10.1182/Blood.V122.21.213.213  0.331
2013 Fitzgerald A, Osman A, Neskey D, Patel A, Skinner H, McDonnell T, Myers J. Abstract 432: Reactive oxygen species and p21Waf1/Cip1are essential for radiation-induced accelerated senescence of head and neck cancer cells. Cancer Research. 73: 432-432. DOI: 10.1158/1538-7445.Am2013-432  0.501
2012 Xu-Monette ZY, Jeffrey Medeiros L, Li Y, Orlowski RZ, Andreeff M, Bueso-Ramos CE, Greiner TC, McDonnell TJ, Young KH. Dysfunction of the TP53 tumor suppressor gene in lymphoid malignancies Blood. 119: 3668-3683. PMID 22275381 DOI: 10.1182/Blood-2011-11-366062  0.477
2012 Samaniego F, Wise JF, Tao R, Zhu H, Ao X, Chen Z, Zhuang W, Braun FK, Mathur R, Romaguera JE, Fayad L, Wang M, McLaughlin P, McDonnell TJ, Patel KP, et al. Regulation of Fas-mediated Apoptosis in B-Cell Lymphomas by Nucleolin. Blood. 120: 2406-2406. DOI: 10.1182/Blood.V120.21.2406.2406  0.52
2011 Piya S, White EJ, Klein SR, Jiang H, McDonnell TJ, Gomez-Manzano C, Fueyo J. The E1B19K oncoprotein complexes with Beclin 1 to regulate autophagy in adenovirus-infected cells. Plos One. 6: e29467. PMID 22242123 DOI: 10.1371/Journal.Pone.0029467  0.433
2011 Kadowaki Y, Chari NS, Teo AE, Hashi A, Spurgers KB, McDonnell TJ. PI3 Kinase inhibition on TRAIL-induced apoptosis correlates with androgen-sensitivity and p21 expression in prostate cancer cells. Apoptosis : An International Journal On Programmed Cell Death. 16: 627-35. PMID 21437722 DOI: 10.1007/S10495-011-0591-3  0.797
2010 Jiang H, Martin V, Gomez-Manzano C, Johnson DG, Alonso M, White E, Xu J, McDonnell TJ, Shinojima N, Fueyo J. The RB-E2F1 pathway regulates autophagy. Cancer Research. 70: 7882-93. PMID 20807803 DOI: 10.1158/0008-5472.Can-10-1604  0.466
2010 Liang M, Han X, Vadhan-Raj S, Nguyen M, Zhang YH, Fernandez M, Drakos E, Konoplev SN, Yin CC, Miranda RN, McDonnell TJ, Medeiros LJ, Bueso-Ramos CE. HDM4 is overexpressed in mantle cell lymphoma and its inhibition induces p21 expression and apoptosis. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 23: 381-91. PMID 20062013 DOI: 10.1038/modpathol.2009.170  0.429
2010 Chari NS, Teo AEK, Medeiros LJ, McDonnell TJ. Abstract 5168: Interaction of sonic hedgehog and TP53/TP63 networks in lymphoma cells Cancer Research. 70: 5168-5168. DOI: 10.1158/1538-7445.Am10-5168  0.492
2010 Jiang H, Martin V, Gomez-Manzano C, Johnson DG, Alonso M, White EJ, Xu J, McDonnell TJ, Shinojima N, Fueyo J. Abstract 4836: RB/E2F1 in the crossroad of autophagy and apoptosis Cancer Research. 70: 4836-4836. DOI: 10.1158/1538-7445.Am10-4836  0.53
2009 Tsavachidou D, McDonnell TJ, Wen S, Wang X, Vakar-Lopez F, Pisters LL, Pettaway CA, Wood CG, Do KA, Thall PF, Stephens C, Efstathiou E, Taylor R, Menter DG, Troncoso P, et al. Selenium and vitamin E: cell type- and intervention-specific tissue effects in prostate cancer. Journal of the National Cancer Institute. 101: 306-20. PMID 19244175 DOI: 10.1093/Jnci/Djn512  0.369
2009 Chari NS, Pinaire NL, Thorpe L, Medeiros LJ, Routbort MJ, McDonnell TJ. The p53 tumor suppressor network in cancer and the therapeutic modulation of cell death. Apoptosis : An International Journal On Programmed Cell Death. 14: 336-47. PMID 19229632 DOI: 10.1007/S10495-009-0327-9  0.709
2009 Chari NS, Teo AEK, Medeiros LJ, McDonnell TJ. Simultaneous Targeting of SHH/ p53 Pathways in Large B Cell Lymphomas. Blood. 114: 1730-1730. DOI: 10.1182/Blood.V114.22.1730.1730  0.505
2008 McDonnell TJ, Chari NS, Cho-Vega JH, Troncoso P, Wang X, Bueso-Ramos CE, Coombes K, Brisbay S, Lopez R, Prendergast G, Logothetis C, Do KA. Biomarker expression patterns that correlate with high grade features in treatment naive, organ-confined prostate cancer. Bmc Medical Genomics. 1: 1. PMID 18237448 DOI: 10.1186/1755-8794-1-1  0.388
2008 Wergeland L, Spurgers KB, Oveland E, Høiby T, Cascallo M, Honda T, Lorens JB, Lozano G, McDonnell TJ, Gjertsen BT. Bcl-2 Protects against p53-Induced Apoptosis through Hdm2 Blood. 112: 5333-5333. DOI: 10.1182/Blood.V112.11.5333.5333  0.773
2007 Cho-Vega JH, Tsavachidis S, Do KA, Nakagawa J, Medeiros LJ, McDonnell TJ. Dicarbonyl/L-xylulose reductase: a potential biomarker identified by laser-capture microdissection-micro serial analysis of gene expression of human prostate adenocarcinoma. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 16: 2615-22. PMID 18086765 DOI: 10.1158/1055-9965.EPI-07-0684  0.322
2007 Kim J, Tsavachidou D, Do K, Wen S, Babaian R, Pisters L, Pettaway C, Troncoso P, Logothetis C, McDonnell T. Differential gene expression in preoperative study of selenium and vitamin E chemoprevention in prostate cancer Journal of Clinical Oncology. 25: 1523-1523. DOI: 10.1200/Jco.2007.25.18_Suppl.1523  0.398
2006 Wang J, Do KA, Wen S, Tsavachidis S, McDonnell TJ, Logothetis CJ, Coombes KR. Merging microarray data, robust feature selection, and predicting prognosis in prostate cancer. Cancer Informatics. 2: 87-97. PMID 19458761 DOI: 10.4137/Cin.S0  0.31
2006 Khor LY, Desilvio M, Li R, McDonnell TJ, Hammond ME, Sause WT, Pilepich MV, Okunieff P, Sandler HM, Pollack A. Bcl-2 and bax expression and prostate cancer outcome in men treated with radiotherapy in Radiation Therapy Oncology Group protocol 86-10. International Journal of Radiation Oncology, Biology, Physics. 66: 25-30. PMID 16814949 DOI: 10.1016/J.Ijrobp.2006.03.056  0.459
2006 Spurgers KB, Gold DL, Coombes KR, Bohnenstiehl NL, Mullins B, Meyn RE, Logothetis CJ, McDonnell TJ. Identification of cell cycle regulatory genes as principal targets of p53-mediated transcriptional repression. The Journal of Biological Chemistry. 281: 25134-42. PMID 16798743 DOI: 10.1074/Jbc.M513901200  0.772
2006 Spurgers KB, Chari NS, Bohnenstiehl NL, McDonnell TJ. Molecular mediators of cell death in multistep carcinogenesis: a path to targeted therapy. Cell Death and Differentiation. 13: 1360-70. PMID 16763617 DOI: 10.1038/Sj.Cdd.4401986  0.768
2006 Kim J, Wang X, Babaian R, Pisters L, Pettaway C, Wood C, Sabichi A, McDonnell T, Logothetis C, Troncoso P. A preoperative model evaluating the tissue effects of chemopreventive agents in low-volume prostate cancer Journal of Clinical Oncology. 24: 1007-1007. DOI: 10.1200/Jco.2006.24.18_Suppl.1007  0.366
2005 Cho-Vega JH, Troncoso P, Do KA, Rago C, Wang X, Tsavachidis S, Medeiros LJ, Spurgers K, Logothetis C, McDonnell TJ. Combined laser capture microdissection and serial analysis of gene expression from human tissue samples. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 18: 577-84. PMID 15529182 DOI: 10.1038/Modpathol.3800327  0.747
2004 Cho-Vega JH, Rassidakis GZ, Admirand JH, Oyarzo M, Ramalingam P, Paraguya A, McDonnell TJ, Amin HM, Medeiros LJ. MCL-1 expression in B-cell non-Hodgkin's lymphomas. Human Pathology. 35: 1095-100. PMID 15343511 DOI: 10.1016/J.Humpath.2004.04.018  0.436
2004 Amin HM, McDonnell TJ, Ma Y, Lin Q, Fujio Y, Kunisada K, Leventaki V, Das P, Rassidakis GZ, Cutler C, Medeiros LJ, Lai R. Selective inhibition of STAT3 induces apoptosis and G(1) cell cycle arrest in ALK-positive anaplastic large cell lymphoma. Oncogene. 23: 5426-34. PMID 15184887 DOI: 10.1038/Sj.Onc.1207703  0.505
2004 Majumder PK, Febbo PG, Bikoff R, Berger R, Xue Q, McMahon LM, Manola J, Brugarolas J, McDonnell TJ, Golub TR, Loda M, Lane HA, Sellers WR. mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways. Nature Medicine. 10: 594-601. PMID 15156201 DOI: 10.1038/Nm1052  0.47
2004 Pisters LL, Pettaway CA, Troncoso P, McDonnell TJ, Stephens LC, Wood CG, Do KA, Brisbay SM, Wang X, Hossan EA, Evans RB, Soto C, Jacobson MG, Parker K, Merritt JA, et al. Evidence that transfer of functional p53 protein results in increased apoptosis in prostate cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 2587-93. PMID 15102659  0.396
2004 Honda T, Coppola S, Ghibelli L, Cho SH, Kagawa S, Spurgers KB, Brisbay SM, Roth JA, Meyn RE, Fang B, McDonnell TJ. GSH depletion enhances adenoviral bax-induced apoptosis in lung cancer cells. Cancer Gene Therapy. 11: 249-55. PMID 15002033 DOI: 10.1038/Sj.Cgt.7700684  0.773
2004 Rosser CJ, Tanaka M, Pisters LL, Tanaka N, Levy LB, Hoover DC, Grossman HB, McDonnell TJ, Kuban DA, Meyn RE. Adenoviral-mediated PTEN transgene expression sensitizes Bcl-2-expressing prostate cancer cells to radiation. Cancer Gene Therapy. 11: 273-9. PMID 14765130 DOI: 10.1038/Sj.Cgt.7700673  0.501
2004 Drakos E, Rassidakis GZ, Lai R, Herling M, O'Connor SL, Schmitt-Graeff A, McDonnell TJ, Medeiros LJ. Caspase-3 activation in systemic anaplastic large-cell lymphoma. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 17: 109-16. PMID 14657946 DOI: 10.1038/Modpathol.3800039  0.497
2004 Spurgers KB, Coombes KR, Meyn RE, Gold DL, Logothetis CJ, Johnson TJ, McDonnell TJ. A comprehensive assessment of p53-responsive genes following adenoviral-p53 gene transfer in Bcl-2-expressing prostate cancer cells. Oncogene. 23: 1712-23. PMID 14647426 DOI: 10.1038/Sj.Onc.1207293  0.776
2004 Bigelow RL, Chari NS, Unden AB, Spurgers KB, Lee S, Roop DR, Toftgard R, McDonnell TJ. Transcriptional regulation of bcl-2 mediated by the sonic hedgehog signaling pathway through gli-1. The Journal of Biological Chemistry. 279: 1197-205. PMID 14555646 DOI: 10.1074/Jbc.M310589200  0.734
2004 Kew Y, McDonnell TJ. Role of Chemokine Receptor, CXCR4, Expression in Directing Neural Stem Cell Vectors in Brain Tumor Therapy Advances in Anatomic Pathology. 11: 327-328. DOI: 10.1097/01.Pap.0000146225.71670.8A  0.302
2003 Amin HM, Medeiros LJ, Ma Y, Feretzaki M, Das P, Leventaki V, Rassidakis GZ, O'Connor SL, McDonnell TJ, Lai R. Inhibition of JAK3 induces apoptosis and decreases anaplastic lymphoma kinase activity in anaplastic large cell lymphoma. Oncogene. 22: 5399-407. PMID 12934099 DOI: 10.1038/Sj.Onc.1206849  0.426
2003 Rassidakis GZ, Jones D, Lai R, Ramalingam P, Sarris AH, McDonnell TJ, Medeiros LJ. BCL-2 family proteins in peripheral T-cell lymphomas: correlation with tumour apoptosis and proliferation. The Journal of Pathology. 200: 240-8. PMID 12754745 DOI: 10.1002/Path.1346  0.462
2003 Amin HM, McDonnell TJ, Medeiros LJ, Rassidakis GZ, Leventaki V, O'Connor SL, Keating MJ, Lai R. Characterization of 4 mantle cell lymphoma cell lines. Archives of Pathology & Laboratory Medicine. 127: 424-31. PMID 12683869 DOI: 10.1043/0003-9985(2003)127<0424:Comclc>2.0.Co;2  0.383
2003 Sah NK, Munshi A, Kurland JF, McDonnell TJ, Su B, Meyn RE. Translation inhibitors sensitize prostate cancer cells to apoptosis induced by tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) by activating c-Jun N-terminal kinase. The Journal of Biological Chemistry. 278: 20593-602. PMID 12663665 DOI: 10.1074/Jbc.M211010200  0.382
2003 Pollack A, Cowen D, Troncoso P, Zagars GK, von Eschenbach AC, Meistrich ML, McDonnell T. Molecular markers of outcome after radiotherapy in patients with prostate carcinoma: Ki-67, bcl-2, bax, and bcl-x. Cancer. 97: 1630-8. PMID 12655519 DOI: 10.1002/Cncr.11230  0.403
2003 Aranha O, Grignon R, Fernandes N, McDonnell TJ, Wood DP, Sarkar FH. Suppression of human prostate cancer cell growth by ciprofloxacin is associated with cell cycle arrest and apoptosis. International Journal of Oncology. 22: 787-94. PMID 12632069 DOI: 10.3892/Ijo.22.4.787  0.431
2003 Rassidakis GZ, Claret FX, Lai R, Zhang Q, Sarris AH, McDonnell TJ, Medeiros LJ. Expression of p27(Kip1) and c-Jun activation binding protein 1 are inversely correlated in systemic anaplastic large cell lymphoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 1121-8. PMID 12631617  0.332
2003 Bruckheimer EM, Spurgers K, Weigel NL, Logothetis C, McDonnell TJ. Regulation of Bcl-2 expression by dihydrotestosterone in hormone sensitive LNCaP-FGC prostate cancer cells. The Journal of Urology. 169: 1553-7. PMID 12629413 DOI: 10.1097/01.ju.0000055140.91204.c7  0.752
2003 DuHadaway JB, Lynch FJ, Brisbay S, Bueso-Ramos C, Troncoso P, McDonnell T, Prendergast GC. Immunohistochemical analysis of Bin1/Amphiphysin II in human tissues: diverse sites of nuclear expression and losses in prostate cancer. Journal of Cellular Biochemistry. 88: 635-42. PMID 12532338 DOI: 10.1002/Jcb.10380  0.337
2003 Khoury JD, Medeiros LJ, Rassidakis GZ, McDonnell TJ, Abruzzo LV, Lai R. Expression of Mcl-1 in mantle cell lymphoma is associated with high-grade morphology, a high proliferative state, and p53 overexpression. The Journal of Pathology. 199: 90-7. PMID 12474231 DOI: 10.1002/Path.1254  0.484
2003 Lai R, Rassidakis GZ, Medeiros LJ, Leventaki V, Keating M, McDonnell TJ. Expression of STAT3 and its phosphorylated forms in mantle cell lymphoma cell lines and tumours. The Journal of Pathology. 199: 84-9. PMID 12474230 DOI: 10.1002/Path.1253  0.359
2003 McDonnell TJ, O'Connor S. A potential biomarker for endometrial cancer Advances in Anatomic Pathology. 10: 49-50. DOI: 10.1097/00125480-200301000-00009  0.329
2002 Rassidakis GZ, Medeiros LJ, Vassilakopoulos TP, Viviani S, Bonfante V, Nadali G, Herling M, Angelopoulou MK, Giardini R, Chilosi M, Kittas C, McDonnell TJ, Bonadonna G, Gianni AM, Pizzolo G, et al. BCL-2 expression in Hodgkin and Reed-Sternberg cells of classical Hodgkin disease predicts a poorer prognosis in patients treated with ABVD or equivalent regimens. Blood. 100: 3935-41. PMID 12433696 DOI: 10.1182/Blood.V100.12.3935  0.414
2002 Dong QG, Sclabas GM, Fujioka S, Schmidt C, Peng B, Wu T, Tsao MS, Evans DB, Abbruzzese JL, McDonnell TJ, Chiao PJ. The function of multiple IkappaB : NF-kappaB complexes in the resistance of cancer cells to Taxol-induced apoptosis. Oncogene. 21: 6510-9. PMID 12226754 DOI: 10.1038/Sj.Onc.1205848  0.451
2002 Rassidakis GZ, Jones D, Thomaides A, Sen F, Lai R, Cabanillas F, McDonnell TJ, Medeiros LJ. Apoptotic rate in peripheral T-cell lymphomas. A study using a tissue microarray with validation on full tissue sections. American Journal of Clinical Pathology. 118: 328-34. PMID 12219774 DOI: 10.1309/Hkmv-Vmpp-0Ch8-3Dpq  0.368
2002 Honda T, Kagawa S, Spurgers KB, Gjertsen BT, Roth JA, Fang B, Lowe SL, Norris JS, Meyn RE, McDonnell TJ. A recombinant adenovirus expressing wild-type Bax induces apoptosis in prostate cancer cells independently of their Bcl-2 status and androgen sensitivity. Cancer Biology & Therapy. 1: 163-7. PMID 12170776 DOI: 10.4161/Cbt.63  0.786
2002 Cho S, O'Connor SL, McDonnell TJ. Evidence that nucleotide excision repair is attenuated in bax-deficient mammalian cells following ultraviolet irradiation. Experimental Cell Research. 278: 158-65. PMID 12169271 DOI: 10.1006/Excr.2002.5572  0.473
2002 Bubb RS, Komaki R, Hachiya T, Milas I, Ro JY, Langford L, Sawaya R, Putnam JB, Allen P, Cox JD, McDonnell TJ, Brock W, Hong WK, Roth JA, Milas L. Association of Ki-67, p53, and bcl-2 expression of the primary non-small-cell lung cancer lesion with brain metastatic lesion. International Journal of Radiation Oncology, Biology, Physics. 53: 1216-24. PMID 12128123 DOI: 10.1016/S0360-3016(02)02861-4  0.361
2002 Lai R, McDonnell TJ, O'Connor SL, Medeiros LJ, Oudat R, Keating M, Morgan MB, Curiel TJ, Ford RJ. Establishment and characterization of a new mantle cell lymphoma cell line, Mino Leukemia Research. 26: 849-855. PMID 12127561 DOI: 10.1016/S0145-2126(02)00013-9  0.396
2002 Rassidakis GZ, Lai R, McDonnell TJ, Cabanillas F, Sarris AH, Medeiros LJ. Overexpression of Mcl-1 in anaplastic large cell lymphoma cell lines and tumors. The American Journal of Pathology. 160: 2309-10. PMID 12057933 DOI: 10.1016/S0002-9440(10)61178-9  0.4
2002 Fizazi K, Martinez LA, Sikes CR, Johnston DA, Stephens LC, McDonnell TJ, Logothetis CJ, Trapman J, Pisters LL, Ordoñez NG, Troncoso P, Navone NM. The association of p21((WAF-1/CIP1)) with progression to androgen-independent prostate cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 8: 775-81. PMID 11895908  0.387
2001 Honda T, Gjertsen BT, Spurgers KB, Briones F, Lee SJ, Hobbs ML, Meyn RE, Roth JA, Logothetis C, McDonnell TJ. Restoration of bax in prostate cancer suppresses tumor growth and augments therapeutic cell death induction. Anticancer Research. 21: 3141-6. PMID 11848465  0.779
2001 Lowe SL, Rubinchik S, Honda T, McDonnell TJ, Dong JY, Norris JS. Prostate-specific expression of Bax delivered by an adenoviral vector induces apoptosis in LNCaP prostate cancer cells. Gene Therapy. 8: 1363-71. PMID 11571575 DOI: 10.1038/Sj.Gt.3301531  0.456
2001 Kurland JF, Kodym R, Story MD, Spurgers KB, McDonnell TJ, Meyn RE. NF-kappaB1 (p50) homodimers contribute to transcription of the bcl-2 oncogene. The Journal of Biological Chemistry. 276: 45380-6. PMID 11567031 DOI: 10.1074/Jbc.M108294200  0.773
2001 Gomez-Manzano C, Mitlianga P, Fueyo J, Lee HY, Hu M, Spurgers KB, Glass TL, Koul D, Liu TJ, McDonnell TJ, Yung WK. Transfer of E2F-1 to human glioma cells results in transcriptional up-regulation of Bcl-2. Cancer Research. 61: 6693-7. PMID 11559537  0.734
2001 Rassidakis GZ, Sarris AH, Herling M, Ford RJ, Cabanillas F, McDonnell TJ, Medeiros LJ. Differential Expression of BCL-2 Family Proteins in ALK-Positive and ALK-Negative Anaplastic Large Cell Lymphoma of T/Null-Cell Lineage American Journal of Pathology. 159: 527-535. PMID 11485911 DOI: 10.1016/S0002-9440(10)61724-5  0.487
2001 Fernandez A, Udagawa T, Schwesinger C, Beecken WD, Achilles-Gerte E, McDonnell TJ, D'Amato RJ. Angiogenic potential of prostate carcinoma cells overexpressing bcl-2 Journal of the National Cancer Institute. 93: 208-213. PMID 11158189 DOI: 10.1093/Jnci/93.3.208  0.497
2001 Pataer A, Smythe WR, Yu R, Fang B, McDonnell T, Roth JA, Swisher SG. Adenovirus-mediated Bak gene transfer induces apoptosis in mesothelioma cell lines. The Journal of Thoracic and Cardiovascular Surgery. 121: 61-7. PMID 11135160 DOI: 10.1067/Mtc.2001.111419  0.475
2001 McDonnell T, Cowen D, Troncoso P, Zagars G, von Eschenbach A, Meistrich M, Pollack A. Molecular markers of patient outcome in prostate cancer treated with radiotherapy: Ki-67, Bcl-2, Bax, and Bcl-x International Journal of Radiation Oncology*Biology*Physics. 51: 112-113. DOI: 10.1016/S0360-3016(01)02030-2  0.395
2000 Blutt SE, McDonnell TJ, Polek TC, Weigel NL. Calcitriol-Induced Apoptosis in LNCaP Cells Is Blocked By Overexpression of Bcl-21. Endocrinology. 141: 10-17. PMID 28200857 DOI: 10.1210/endo.141.1.7289  0.355
2000 Bruckheimer EM, Brisbay S, Johnson DJ, Gingrich JR, Greenberg N, McDonnell TJ. Bcl-2 accelerates multistep prostate carcinogenesis in vivo. Oncogene. 19: 5251-8. PMID 11077442 DOI: 10.1038/Sj.Onc.1203881  0.384
2000 Bruckheimer EM, Cho S, Brisbay S, Johnson DJ, Gingrich JR, Greenberg N, McDonnell TJ. The impact of bcl-2 expression and bax deficiency on prostate homeostasis in vivo. Oncogene. 19: 2404-12. PMID 10828882 DOI: 10.1038/Sj.Onc.1203571  0.433
2000 Liu G, McDonnell TJ, Montes de Oca Luna R, Kapoor M, Mims B, El-Naggar AK, Lozano G. High metastatic potential in mice inheriting a targeted p53 missense mutation. Proceedings of the National Academy of Sciences of the United States of America. 97: 4174-9. PMID 10760284 DOI: 10.1073/Pnas.97.8.4174  0.315
2000 Kagawa S, Pearson SA, Ji L, Xu K, McDonnell TJ, Swisher SG, Roth JA, Fang B. A binary adenoviral vector system for expressing high levels of the proapoptotic gene bax. Gene Therapy. 7: 75-9. PMID 10680019 DOI: 10.1038/Sj.Gt.3301048  0.426
2000 Fueyo J, Gomez-Manzano C, Alemany R, Lee PS, McDonnell TJ, Mitlianga P, Shi YX, Levin VA, Yung WK, Kyritsis AP. A mutant oncolytic adenovirus targeting the Rb pathway produces anti-glioma effect in vivo. Oncogene. 19: 2-12. PMID 10644974 DOI: 10.1038/Sj.Onc.1203251  0.502
2000 Spurgers K, Briones F, McDonnell TJ. Prostate cancer: another piece to the molecular puzzle. Advances in Anatomic Pathology. 7: 9-12. PMID 10640197 DOI: 10.1097/00125480-200007010-00003  0.724
2000 McDonnell TJ, Montes de Oca Luna R, Cho S, Amelse LL, Chavez-Reyes A, Lozano G. Loss of one but not two mdm2 null alleles alters the tumour spectrum in p53 null mice. The Journal of Pathology. 188: 322-8. PMID 10419603 DOI: 10.1002/(Sici)1096-9896(199907)188:3<322::Aid-Path372>3.0.Co;2-F  0.323
1999 Pisters LL, Pettaway CA, Hossan E, Evans R, Steiner MS, Wood CG, Troncoso P, McDonnell TJ, Fenstenmacher MJ, Logothetis CJ. Intraprostatic AD-p53 gene therapy followed by radical prostatectomy: feasibility and preliminary results. Prostate Cancer and Prostatic Diseases. 2. PMID 12496806 DOI: 10.1038/Sj.Pcan.4500352  0.305
1999 Logsdon MD, Meyn RE, Besa PC, Pugh WC, Stephens LC, Peters LJ, Milas L, Cox JD, Cabanillas F, Brisbay S, Andersen M, McDonnell TJ. Apoptosis and the Bcl-2 gene family -- patterns of expression and prognostic value in stage I and II follicular center lymphoma. International Journal of Radiation Oncology, Biology, Physics. 44: 19-29. PMID 10219790 DOI: 10.1016/S0360-3016(98)00455-6  0.384
1998 Gjertsen BT, Logothetis CJ, McDonnell TJ. Molecular regulation of cell death and therapeutic strategies for cell death induction in prostate carcinoma. Cancer and Metastasis Reviews. 17: 345-351. PMID 10453278 DOI: 10.1023/A:1006170332301  0.511
1998 Herrmann JL, Briones F, Brisbay S, Logothetis CJ, McDonnell TJ. Prostate carcinoma cell death resulting from inhibition of proteasome activity is independent of functional Bcl-2 and P53 Oncogene. 17: 2889-2899. PMID 9879995 DOI: 10.1038/Sj.Onc.1202221  0.472
1998 Beham AW, Sarkiss MG, Brisbay S, Tu S, Eschenbach ACv, McDonnell TJ. Molecular correlates of bcl-2-enhanced growth following androgen-ablation in prostate carcinoma cells in vivo. International Journal of Molecular Medicine. 1: 953-962. PMID 9852630 DOI: 10.3892/Ijmm.1.6.953  0.51
1998 Yu D, Jing T, Liu B, Yao J, Tan M, McDonnell TJ, Hung MC. Overexpression of ErbB2 blocks Taxol-induced apoptosis by upregulation of p21Cip1, which inhibits p34Cdc2 kinase. Molecular Cell. 2: 581-91. PMID 9844631 DOI: 10.1016/S1097-2765(00)80157-4  0.468
1998 Bruckheimer EM, Cho SH, Sarkiss MG, Herrmann J, McDonnell TJ. The Bcl-2 gene family and apoptosis Advances in Biochemical Engineering \/ Biotechnology. 62: 75-105. PMID 9755641 DOI: 10.1007/Bfb0102306  0.423
1998 Tormo M, Tari AM, McDonnell TJ, Cabanillas F, Garcia-Conde J, Lopez-Berestein G. Apoptotic induction in transformed follicular lymphoma cells by Bcl-2 downregulation. Leukemia & Lymphoma. 30: 367-79. PMID 9713967 DOI: 10.3109/10428199809057548  0.441
1998 Fueyo J, Gomez-Manzano C, Yung WK, Liu TJ, Alemany R, McDonnell TJ, Shi X, Rao JS, Levin VA, Kyritsis AP. Overexpression of E2F-1 in glioma triggers apoptosis and suppresses tumor growth in vitro and in vivo. Nature Medicine. 4: 685-90. PMID 9623977 DOI: 10.1038/Nm0698-685  0.477
1998 Voehringer DW, McConkey DJ, McDonnell TJ, Brisbay S, Meyn RE. Bcl-2 expression causes redistribution of glutathione to the nucleus. Proceedings of the National Academy of Sciences of the United States of America. 95: 2956-60. PMID 9501197 DOI: 10.1073/Pnas.95.6.2956  0.448
1998 Rodríguez-Villanueva J, Greenhalgh D, Wang XJ, Bundman D, Cho S, Delehedde M, Roop D, McDonnell TJ. Human keratin-1.bcl-2 transgenic mice aberrantly express keratin 6, exhibit reduced sensitivity to keratinocyte cell death induction, and are susceptible to skin tumor formation Oncogene. 16: 853-863. PMID 9484776 DOI: 10.1038/Sj.Onc.1201610  0.471
1998 Beham A, Schumacher G, McDonnell TJ, Marin MC, Jauch KW. Bcl-2 hemmt p53 induzierte Apoptose nach genotoxischer Schädigung durch Inhibition des nuklearen Imports von p53. Langenbecks Archiv FüR Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft FüR Chirurgie. Kongress. 115: 113-117. DOI: 10.1007/978-3-642-72182-3_25  0.352
1997 Westin P, Lo P, Marin M, Fernandez A, Sarkiss M, Tu S, Brisbay S, Voneschenbach A, McDonnell T. bcl-2 expression confers androgen independence in androgen sensitive prostatic carcinoma. International Journal of Oncology. 10: 113-118. PMID 21533353 DOI: 10.3892/Ijo.10.1.113  0.451
1997 Beham A, Marin MC, Fernandez A, Herrmann J, Brisbay S, Tari AM, Lopez-Berestein G, Lozano G, Sarkiss M, McDonnell TJ. Bcl-2 inhibits p53 nuclear import following DNA damage. Oncogene. 15: 2767-72. PMID 9419967 DOI: 10.1038/Sj.Onc.1201464  0.478
1997 Mirkovic N, Voehringer DW, Story MD, McConkey DJ, McDonnell TJ, Meyn RE. Resistance to radiation-induced apoptosis in Bcl-2-expressing cells is reversed by depleting cellular thiols Oncogene. 15: 1461-1470. PMID 9333022 DOI: 10.1038/Sj.Onc.1201310  0.451
1997 Herrmann JL, Menter DG, Beham A, Eschenbach Av, McDonnell TJ. Regulation of lipid signaling pathways for cell survival and apoptosis by bcl-2 in prostate carcinoma cells. Experimental Cell Research. 234: 442-451. PMID 9260915 DOI: 10.1006/Excr.1997.3653  0.482
1997 Gomez-Manzano C, Fueyo J, Kyritsis AP, McDonnell TJ, Steck PA, Levin VA, Yung WK. Characterization of p53 and p21 functional interactions in glioma cells en route to apoptosis. Journal of the National Cancer Institute. 89: 1036-44. PMID 9230885 DOI: 10.1093/Jnci/89.14.1036  0.472
1997 Logsdon MD, McDonnell TJ, Pugh WC, Besa PC, Cox JD, Cabanillas F, Stephens L, Meyn RE. 81 Apoptosis, mitosis, BCL-2, bax, and BCL-X as predictors of tumor response in stage I and II follicular lymphoma International Journal of Radiation Oncology*Biology*Physics. 39: 175. DOI: 10.1016/S0360-3016(97)80639-6  0.343
1996 Xie K, Huang S, Wang Y, Beltran PJ, Juang SH, Dong Z, Reed JC, McDonnell TJ, McConkey DJ, Fidler IJ. Bcl-2 protects cells from cytokine-induced nitric-oxide-dependent apoptosis Cancer Immunology, Immunotherapy. 43: 109-115. PMID 8954145 DOI: 10.1007/S002620050310  0.492
1996 Roth JA, Nguyen D, Lawrence DD, Kemp BL, Carrasco CH, Ferson DZ, Hong WK, Komaki R, Lee JJ, Nesbitt JC, Pisters KM, Putnam JB, Schea R, Shin DM, Walsh GL, ... ... McDonnell TJ, et al. Retrovirus-mediated wild-type p53 gene transfer to tumors of patients with lung cancer. Nature Medicine. 2: 985-91. PMID 8782455 DOI: 10.1038/Nm0996-985  0.437
1996 Steck K, McDonnell TJ, Sneige N, El-Naggar AK. Flow cytometric analysis of apoptosis and BCL‐2 in primary breast carcinomas: Clinical and biological implications Cytometry. 24: 116-122. PMID 8725660 DOI: 10.1002/(Sici)1097-0320(19960601)24:2<116::Aid-Cyto3>3.0.Co;2-H  0.44
1996 Sarkiss M, Hsu B, El-Naggar AK, McDonnell TJ. The Clinical Relevance and Assessment of Apoptotic Cell Death Advances in Anatomic Pathology. 3: 205-211. DOI: 10.1097/00125480-199607000-00001  0.513
1996 Tu SM, McConnell K, Marin MC, Campbell ML, Fernandez A, Von Eschenbach AC, McDonnell TJ. Corrigendum: Combination adriamycin and suramin induces apoptosis in bcl-2 expressing prostate carcinoma cells (Cancer Letters (1995) 93 (147-155)) Cancer Letters. 99: 247. DOI: 10.1016/0304-3835(95)04094-3  0.5
1995 Rodríguez‐Villanueva J, McDonnell TJ. Induction of apoptotic cell death in non‐melanoma skin cancer by interferon‐α International Journal of Cancer. 61: 110-114. PMID 7705922 DOI: 10.1002/Ijc.2910610119  0.395
1995 Marin MC, Hsu B, Stephens LC, Brisbay S, McDonnell TJ. The functional basis of c-myc and bcl-2 complementation during multistep lymphomagenesis in vivo. Experimental Cell Research. 217: 240-7. PMID 7698223 DOI: 10.1006/Excr.1995.1083  0.399
1995 Steck KD, McDonnell TJ, El‐Naggar AK. Flow cytometric analysis of apoptosis and BCL‐2 in human solid neoplasms Cytometry. 20: 154-161. PMID 7664626 DOI: 10.1002/Cyto.990200208  0.467
1995 Hsu B, Marin MC, McDonnell TJ. Cell death regulation during multistep lymphomagenesis Cancer Letters. 94: 17-23. PMID 7621440 DOI: 10.1016/0304-3835(95)03836-L  0.451
1995 Tu SM, McConnell K, Marin MC, Campbell ML, Fernandez A, von Eschenbach AC, McDonnell TJ. Combination adriamycin and suramin induces apoptosis in bcl-2 expressing prostate carcinoma cells. Cancer Letters. 93: 147-55. PMID 7621422 DOI: 10.1016/0304-3835(95)03795-X  0.477
1995 McDonnell TJ, Meyn RE, Robertson LE. Implications of apoptotic cell death regulation in cancer therapy Seminars in Cancer Biology. 6: 53-60. PMID 7548842 DOI: 10.1006/Scbi.1995.0007  0.502
1993 McDonnell TJ. Cell division versus cell death: a functional model of multistep neoplasia Molecular Carcinogenesis. 8: 209-213. PMID 8280368 DOI: 10.1002/Mc.2940080402  0.427
1993 McDonnell TJ, Marin MC, Hsu B, Brisbay SM, McConnell K, Tu S, Campbell ML, Rodriguez-Villanueva J. The bcl-2 oncogene: Apoptosis and neoplasia Radiation Research. 136: 307-312. DOI: 10.2307/3578541  0.479
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